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Lucena-Cacace Antonio  Lucena.Cacace Antonio

ORCIDConnect your ORCID iD *help
… Alternative Names

Lucena.Cacace Antonio  ルセナカカセ アントニオ

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Researcher Number 60832748
Other IDs
Affiliation (Current) 2025: 大阪大学, ヒューマン・メタバース疾患研究拠点, 特任准教授(常勤)
Affiliation (based on the past Project Information) *help 2024: 大阪大学, ヒューマン・メタバース疾患研究拠点, 特任准教授(常勤)
2022: 京都大学, iPS細胞研究所, 特命助教
2020 – 2022: 京都大学, iPS細胞研究所, 特定研究員
Review Section/Research Field
Principal Investigator
Basic Section 53020:Cardiology-related
Keywords
Principal Investigator
hiPSC-EPI / epicardium / heart / Cell Cycle / Cardiology / Regeneration / Reprogramming / hiPSC-CMs / cell cycle / regeneration … More / Heart / nanomedic / cellular bioengineering / stem cells / disease modeling / tissue bioengineering / eht / small molecules / tnni3 / cardiac maturation / Stem Cell Research / hiPSC-CM / TNNI3 / Cardiac maturation Less
  • Research Projects

    (3 results)
  • Research Products

    (5 results)
  •  Improving Functional Regeneration and Engraftment of Cardiomyocytes Derived from Human Induced Pluripotent Stem Cells by Brief Cycles of Transient ReprogrammingPrincipal Investigator

    • Principal Investigator
      Lucena.Cacace Antonio
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53020:Cardiology-related
    • Research Institution
      Osaka University
  •  Generation of highly regenerative human induced pluripotent stem cell-derived epicardial cells for cardiac repair and regenerationPrincipal Investigator

    • Principal Investigator
      Lucena.Cacace Antonio
    • Project Period (FY)
      2022 – 2023
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 53020:Cardiology-related
    • Research Institution
      Kyoto University
  •  Human induced pluripotent stem cell derived cardiomyocyte maturation by DNA integrative free-delivery of key regulatorsPrincipal Investigator

    • Principal Investigator
      Lucena-Cacace Antonio
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 53020:Cardiology-related
    • Research Institution
      Kyoto University

All 2022 2020

All Journal Article Presentation Patent

  • [Journal Article] Immunosuppressants Tacrolimus and Sirolimus revert the cardiac antifibrotic properties of p38-MAPK inhibition in 3D-multicellular human iPSC-heart organoids2022

    • Author(s)
      Yu Tian, Yuta Tsujisaka, Vanessa Y Li, Kanae Tani, Antonio Lucena-Cacace, Yoshinori Yoshida
    • Journal Title

      Front Cell Dev Biol

      Volume: 10

    • DOI

      10.3389/fcell.2022.1001453

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K17078
  • [Journal Article] CDH18 is a fetal epicardial biomarker regulating differentiation towards vascular smooth muscle cells2022

    • Author(s)
      Julia Junghof, Yuta Kogure, Tian Yu, Eva Maria Verdugo-Sivianes, Megumi Narita, Antonio Lucena-Cacace, Yoshinori Yoshida
    • Journal Title

      NPJ Regenerative Medicine

      Volume: 7 Issue: 1

    • DOI

      10.1038/s41536-022-00207-w

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K17078
  • [Journal Article] Analysis of Transcriptional Profiling of Chamber-Specific Human Cardiac Myocytes Derived from Pluripotent Stem Cells2022

    • Author(s)
      Antonio Lucena-Cacace, Yoshinori Yoshida
    • Journal Title

      Methods Mol Biol

      Volume: 2320 Pages: 219-232

    • DOI

      10.1007/978-1-0716-1484-6_20

    • ISBN
      9781071614839, 9781071614846
    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K17078
  • [Patent] Mature-cardiomyocyte production method2020

    • Inventor(s)
      Antonio Lucena-Cacace, etc
    • Industrial Property Rights Holder
      Antonio Lucena-Cacace, etc
    • Industrial Property Rights Type
      特許
    • Filing Date
      2020
    • Acquisition Date
      2021
    • Overseas
    • Data Source
      KAKENHI-PROJECT-20K17078
  • [Presentation] Maturation of human iPSC-derived cardiomyocytes2022

    • Author(s)
      Antonio Lucena-Cacace
    • Organizer
      Leducq Network: Towards Precision Medicine with Human iPSCs for Cardiac Channelopathies (Stanford University, USA)
    • Invited
    • Data Source
      KAKENHI-PROJECT-20K17078

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