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ISOZAKI Shotaro  磯崎 翔太郎

… Alternative Names

Isozaki Shotaro  磯崎 翔太郎

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Researcher Number 60834504
Other IDs
  • ORCIDhttps://orcid.org/0000-0003-4847-4291
Affiliation (Current) 2025: 東海大学, 医学部, 講師
Affiliation (based on the past Project Information) *help 2024: 東海大学, 医学部, 講師
2022 – 2023: 東海大学, 医学部, 助教
2019 – 2021: 旭川医科大学, 大学病院, 医員
Review Section/Research Field
Principal Investigator
Basic Section 58040:Forensics medicine-related
Except Principal Investigator
Basic Section 58040:Forensics medicine-related
Keywords
Principal Investigator
物理化学的皮膚障害 / 凍傷 / 受傷機序推定 / βカテニン / 熱傷 / DNA / 法医遺伝学 / 法医学 / 年齢推定 / LNA / 人工核酸 / メチル化 / Locked Nucleic Acid … More
Except Principal Investigator
… More CTNNA3 / MYH1 / プロテオーム / 突然死 / 異方性 / タンパク質 / 質量分析 / 心肥大 / 心臓性突然死 Less
  • Research Projects

    (3 results)
  • Research Products

    (38 results)
  • Co-Researchers

    (6 People)
  •  Anisotropic proteomic profiling in sudden cardiac death

    • Principal Investigator
      垣本 由布
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 58040:Forensics medicine-related
    • Research Institution
      Tokai University
  •  特異的シグナル伝達経路解析に基づく革新的な法医学的皮膚病変評価法の確立Principal Investigator

    • Principal Investigator
      磯崎 翔太郎
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 58040:Forensics medicine-related
    • Research Institution
      Tokai University
  •  DNA methylation-based forensic age prediction in Japanese populations using locked nucleic acid.Principal Investigator

    • Principal Investigator
      Isozaki Shotaro
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 58040:Forensics medicine-related
    • Research Institution
      Asahikawa Medical College

All 2024 2023 2022 2021 2020 2019

All Journal Article Presentation Patent

  • [Journal Article] Unexpected sudden death on arrival in a healthy middle-aged man associated with COVID-19-related diffuse cardiac injury: A case report2024

    • Author(s)
      Isozaki Shotaro、Kakimoto Yu、Ikeda Haruka、Matsushima Yutaka、Tsuboi Akio、Osawa Motoki
    • Journal Title

      Heliyon

      Volume: 10 Issue: 1 Pages: e23460-e23460

    • DOI

      10.1016/j.heliyon.2023.e23460

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K17411
  • [Journal Article] DNA methylation-based age estimation and quantification of the degradation levels of bisulfite-converted DNA2024

    • Author(s)
      Shiga Mihiro、Asari Masaru、Takahashi Yuta、Isozaki Shotaro、Hoshina Chisato、Mori Kanae、Namba Ryo、Okuda Katsuhiro、Shimizu Keiko
    • Journal Title

      Legal Medicine

      Volume: 67 Pages: 102336-102336

    • DOI

      10.1016/j.legalmed.2023.102336

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K17411
  • [Journal Article] Assessment of maxillary sinus fluid volume for postmortem diagnosis of drowning2024

    • Author(s)
      Kakimoto Y.、Ohno S.、Saito T.、Isozaki S.、Ikeda H.、Matsushima Y.、Ueda A.、Tsuboi A.、Osawa M.
    • Journal Title

      Radiography

      Volume: 30 Issue: 1 Pages: 308-312

    • DOI

      10.1016/j.radi.2023.12.001

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K17411
  • [Journal Article] A case of a motor vehicle collision suspected as associated with development of angiosarcoma2024

    • Author(s)
      Ikeda Haruka、Isozaki Shotaro、Kakimoto Yu、Ueda Atsushi、Tsuboi Akio、Osawa Motoki
    • Journal Title

      Legal Medicine

      Volume: 67 Pages: 102332-102332

    • DOI

      10.1016/j.legalmed.2023.102332

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K17411
  • [Journal Article] 人工核酸LNAを用いた高感度なDNAメチル化率測定法2023

    • Author(s)
      磯崎翔太郎
    • Journal Title

      犯罪学雑誌

      Volume: 89 Pages: 10-14

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K17411
  • [Journal Article] Proteomic profiling of sudden cardiac death with acquired cardiac hypertrophy2023

    • Author(s)
      Kakimoto Yu、Ueda Atsushi、Ito Masatoshi、Tanaka Masayuki、Kubota Tomoko、Isozaki Shotaro、Osawa Motoki
    • Journal Title

      International Journal of Legal Medicine

      Volume: 137 Issue: 5 Pages: 1453-1461

    • DOI

      10.1007/s00414-023-03038-6

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K17411, KAKENHI-PROJECT-20K10565
  • [Journal Article] Bioprotective role of platelet-derived microvesicles in hypothermia: Insight into the differential characteristics of peripheral and splenic platelets2023

    • Author(s)
      Horioka Kie、Tanaka Hiroki、Okaba Keisuke、Yamada Shinnosuke、Hayakawa Akira、Ishii Namiko、Motomura Ayumi、Inoue Hiroyuki、Takauji Shuhei、Isozaki Shotaro、Ogawa Katsuhiro、Yajima Daisuke、Druid Henrik、Pakanen Lasse、Porvari Katja
    • Journal Title

      Thrombosis Research

      Volume: 223 Pages: 155-167

    • DOI

      10.1016/j.thromres.2023.01.006

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K17411, KAKENHI-PROJECT-21K17328, KAKENHI-PROJECT-22K17412, KAKENHI-PROJECT-23K16376
  • [Journal Article] 乳幼児突然死にけるブチリルコリンエステラーゼの変異解析2023

    • Author(s)
      上田篤, 磯崎翔太郎, 垣本由布, 内藤春顕, 大澤資樹
    • Journal Title

      DNA多型

      Volume: 31 Pages: 124-127

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K17411
  • [Journal Article] Age prediction by methylation analysis of small amounts of <scp>DNA</scp> using locked nucleic acids2022

    • Author(s)
      Takahashi Yuta、Asari Masaru、Isozaki Shotaro、Hoshina Chisato、Okuda Katsuhiro、Mori Kanae、Namba Ryo、Ochiai Wataru、Shimizu Keiko
    • Journal Title

      Journal of Forensic Sciences

      Volume: 68 Issue: 1 Pages: 267-274

    • DOI

      10.1111/1556-4029.15144

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K17411
  • [Journal Article] Soluble thrombomodulin ameliorates aberrant hemostasis after rewarming in a rat accidental hypothermia model2022

    • Author(s)
      Takauji Shuhei、Tanaka Hiroki、Hayakawa Mineji、Horioka Kie、Isozaki Shotaro、Konishi Hiroaki
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 587 Pages: 1-8

    • DOI

      10.1016/j.bbrc.2021.11.086

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K19477, KAKENHI-PROJECT-19K16484, KAKENHI-PROJECT-21K17328, KAKENHI-PROJECT-19KK0225
  • [Journal Article] Probiotic-derived heptelidic acid exerts antitumor effects on extraintestinal melanoma through glyceraldehyde-3-phosphate dehydrogenase activity control2022

    • Author(s)
      Isozaki Shotaro、Konishi Hiroaki、Tanaka Hiroki、Yamamura Chikage、Moriichi Kentaro、Ogawa Naoki、Fujiya Mikihiro
    • Journal Title

      BMC Microbiology

      Volume: 22 Issue: 1 Pages: 110-110

    • DOI

      10.1186/s12866-022-02530-0

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K16484, KAKENHI-PROJECT-19KK0225, KAKENHI-PROJECT-21K07929, KAKENHI-PROJECT-22K17411
  • [Journal Article] Hypoxia-induced nuclear translocation of β-catenin in the healing process of frostbite2022

    • Author(s)
      Isozaki Shotaro、Tanaka Hiroki、Horioka Kie、Konishi Hiroaki、Kashima Shin、Takauji Shuhei、Fujiya Mikihiro、Druid Henrik
    • Journal Title

      Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

      Volume: 1868 Issue: 6 Pages: 166385-166385

    • DOI

      10.1016/j.bbadis.2022.166385

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K19477, KAKENHI-PROJECT-19K16484, KAKENHI-PROJECT-21K17328, KAKENHI-PROJECT-19KK0225, KAKENHI-PROJECT-22K17411
  • [Journal Article] Multidirectional analysis for a colchicine poisoning case revealed detail cause of death and its mechanism2022

    • Author(s)
      Okuda Katsuhiro、Isozaki Shotaro、Asari Masaru、Tanaka Hiroki、Horioka Kie、Takahashi Yuta、Hoshina Chisato、Yamada Hiromi、Mori Kanae、Namba Ryo、Shiono Hiroshi、Ogawa Katsuhiro、Shimizu Keiko
    • Journal Title

      Legal Medicine

      Volume: 58 Pages: 102092-102092

    • DOI

      10.1016/j.legalmed.2022.102092

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K17411
  • [Journal Article] An instance of homicide by electrocution with hand-made electrode plates2022

    • Author(s)
      Kakimoto Yu、Ikeda Haruka、Matsushima Yutaka、Tsuboi Akio、Ueda Atsushi、Isozaki Shotaro、Osawa Motoki
    • Journal Title

      Forensic Science, Medicine and Pathology

      Volume: - Issue: 4 Pages: 568-572

    • DOI

      10.1007/s12024-022-00566-2

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K17411
  • [Journal Article] Probiotic derived polyphosphate accelerates intestinal epithelia wound healing through inducing platelet-derived mediators.2021

    • Author(s)
      Isozaki S, Konishi H, Fujiya M, Tanaka H, Murakami Y, Kashima S, Ando K, Ueno N, Moriichi K, Okumura T.
    • Journal Title

      Mediators of Inflammation

      Volume: 2021:5582943 Pages: 1-14

    • DOI

      10.1155/2021/5582943

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07927, KAKENHI-PROJECT-19K16484, KAKENHI-PROJECT-19K19477, KAKENHI-PROJECT-19KK0225, KAKENHI-PROJECT-19K17419
  • [Journal Article] Treatment of hepatocellular carcinoma with autologous platelets encapsulating sorafenib or lenvatinib: A novel therapy exploiting tumor‐platelet interactions2021

    • Author(s)
      Tanaka Hiroki、Horioka Kie、Hasebe Takumu、Sawada Koji、Nakajima Shunsuke、Konishi Hiroaki、Isozaki Shotaro、Goto Masanori、Fujii Yumiko、Kamikokura Yuki、Ogawa Katsuhiro、Nishikawa Yuji
    • Journal Title

      International Journal of Cancer

      Volume: 150 Issue: 10 Pages: 1640-1653

    • DOI

      10.1002/ijc.33915

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K19477, KAKENHI-PROJECT-21K07167, KAKENHI-PROJECT-19K16484, KAKENHI-PROJECT-21K17328, KAKENHI-PROJECT-19KK0225, KAKENHI-PROJECT-22K17411
  • [Journal Article] The Optimal Dose of Tacrolimus in Combination Therapy with an Anti-TNFα Antibody in a Mouse Colitis Model2021

    • Author(s)
      Murakami Yuki、Fujiya Mikihiro、Konishi Hiroaki、Isozaki Shotaro、Sugiyama Yuya、Kobayashi Yu、Sasaki Takahiro、Kunogi Takehito、Takahashi Keitaro、Ando Katsuyoshi、Ueno Nobuhiro、Kashima Shin、Moriichi Kentaro、Tanabe Hiroki、Okumura Toshikatsu
    • Journal Title

      Biological and Pharmaceutical Bulletin

      Volume: 44 Issue: 4 Pages: 564-570

    • DOI

      10.1248/bpb.b20-00916

    • NAID

      130008014301

    • ISSN
      0918-6158, 1347-5215
    • Year and Date
      2021-04-01
    • Language
      English
    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K16484, KAKENHI-PROJECT-19K19477, KAKENHI-PROJECT-19K17419
  • [Journal Article] Polyphosphate, derived from the probiotic Lactobacillus brevis, modulates the intestinal microbiome and attenuates acute pancreatitis.2021

    • Author(s)
      Takauji S, Konishi H, Fujiya M, Ueno N, Tanaka H, Sato H, Isozaki S, Kashima S, Moriichi K, Mizukami Y, Okumura T.
    • Journal Title

      Dig Dis Sci

      Volume: - Issue: 11 Pages: 1-1

    • DOI

      10.1007/s10620-020-06747-9

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07927, KAKENHI-PROJECT-19K16484, KAKENHI-PROJECT-19K17480, KAKENHI-PROJECT-19K19477, KAKENHI-PROJECT-18K08906, KAKENHI-PROJECT-20H03655
  • [Journal Article] Probiotic Aspergillus oryzae produces anti-tumor mediator and exerts anti-tumor effects in pancreatic cancer through the p38 MAPK signaling pathway.2021

    • Author(s)
      Konishi H, Isozaki S, Kashima S, Moriichi K, Ichikawa S, Yamamoto K, Yamamura C, Ando K, Ueno N, Akutsu H, Ogawa N, Fujiya M.
    • Journal Title

      Sci Rep

      Volume: 11 Issue: 1 Pages: 11070-11070

    • DOI

      10.1038/s41598-021-90707-4

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07927, KAKENHI-PROJECT-19K19477, KAKENHI-PROJECT-19H03345, KAKENHI-PROJECT-19K16484, KAKENHI-PROJECT-19K17419
  • [Journal Article] Low temperature induces von-willebrand factor expression via increased early growth response 1 transcriptional activity in splenic sinusoidal endothelial cells.2020

    • Author(s)
      Horioka K, Tanaka H, Isozaki S, Konishi H, Addo L, Takauji S, Druid H.
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 526 Issue: 1 Pages: 239-245

    • DOI

      10.1016/j.bbrc.2020.03.073

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K16484, KAKENHI-PROJECT-19K19477, KAKENHI-PROJECT-19KK0225
  • [Journal Article] Rewarming from accidental hypothermia enhances whole blood clotting properties in a murine model2020

    • Author(s)
      Horioka Kie、Tanaka Hiroki、Isozaki Shotaro、Konishi Hiroaki、Addo Lynda、Takauji Shuhei、Druid Henrik
    • Journal Title

      Thrombosis Research

      Volume: 195 Pages: 114-119

    • DOI

      10.1016/j.thromres.2020.07.022

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K19477, KAKENHI-PROJECT-19KK0225
  • [Patent] 血小板凝集剤2020

    • Inventor(s)
      藤谷幹浩,小西弘晃,田中宏樹,磯崎翔太郎,大町佳宏,尾川直樹
    • Industrial Property Rights Holder
      藤谷幹浩,小西弘晃,田中宏樹,磯崎翔太郎,大町佳宏,尾川直樹
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2020-001319
    • Filing Date
      2020
    • Data Source
      KAKENHI-PROJECT-19K19477
  • [Presentation] 溺死診断における上顎洞内液体貯留の有用性2024

    • Author(s)
      磯崎翔太郎, 垣本由布, 大野将平, 齊藤卓也, 池田はるか, 松島裕, 上田篤, 坪井秋男, 大澤資樹
    • Organizer
      第25回法医画像勉強会
    • Data Source
      KAKENHI-PROJECT-22K17411
  • [Presentation] 凍傷の創傷治癒過程における角化細胞のβ-catenin核内移行と機能解析2023

    • Author(s)
      磯崎翔太郎, 田中 宏樹, 堀岡 希衣, 大澤 資樹, Henrik Druid
    • Organizer
      第53回日本創傷治癒学会
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K17411
  • [Presentation] 健常および肥大心における心筋三層のプロテオーム解析2023

    • Author(s)
      垣本由布、上田篤、池田はるか、木村弥生、秋山知子、磯崎翔太郎、大澤資樹
    • Organizer
      第113回日本病理学総会
    • Data Source
      KAKENHI-PROJECT-23K27868
  • [Presentation] Proteomic approach to sudden cardiac death with acquired cardiac hypertrophy.2023

    • Author(s)
      Y Kakimoto, A Ueda, M Ito, M Tanaka, T Kubota, S Isozaki, M Osawa.
    • Organizer
      10th Biennial Meeting of the Association for European Cardiovascular Pathology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K27868
  • [Presentation] 死亡前に高次脳機能障害が認められた脳出血の一例2023

    • Author(s)
      磯崎翔太郎, 池田はるか, 松島 裕, 坪井秋男, 上田 篤, 垣本由布, 大澤資樹
    • Organizer
      第107次日本法医学会学術全国集会
    • Data Source
      KAKENHI-PROJECT-22K17411
  • [Presentation] 有益微生物由来分子のDoxorubicin誘発慢性心不全モデルマウスへの影響2023

    • Author(s)
      磯崎翔太郎, 池田はるか, 垣本由布, 松島裕, 坪井秋男, 上田篤, 大澤資樹
    • Organizer
      第92回日本法医学会学術関東地方集会
    • Data Source
      KAKENHI-PROJECT-22K17411
  • [Presentation] PROBIOTIC-DERIVED HEPTELIDIC ACID EXERTS ANTITUMOR EFFECTS ON DISTANT MELANOMA THROUGH THE INHIBITION OF GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE ACTIVITY2022

    • Author(s)
      Isozaki S, Konishi H, Tanaka H, Yamamura C, Kobayashi Y, Sugiyama Y, Murakami Y, Sasaki T, Kunigi T, Takahashi K, Ando K, Ueno N, Kashima S, Moriichi K, Fujiya M
    • Organizer
      Digestive Disease Week
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K17411
  • [Presentation] COVID-19関連心筋炎と考えられた壮年男性の一剖検例2022

    • Author(s)
      磯崎翔太郎, 垣本由布, 池田はるか, 齊藤卓也, 松島裕, 坪井秋男, 大澤資樹
    • Organizer
      第5回日本法医病理学会学術全国集会
    • Data Source
      KAKENHI-PROJECT-22K17411
  • [Presentation] Molecular pathological elucidation of frostbite using mouse model.2022

    • Author(s)
      Isozaki S, Tanaka H, Horioka K, Konishi H, Hayakawa A, Kashima S, Druid H
    • Organizer
      The joint meeting of the 21st Nordic Conference on Forensic Medicine (NCFM) and the 6th Annual Meeting of the Nordic Association of Forensic Toxicologists (NAFT).
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K17411
  • [Presentation] Hypoxia-induced nuclear translocation of β-catenin provokes EMT in the healing process of frostbite2022

    • Author(s)
      磯崎翔太郎, 田中宏樹, 堀岡希衣, 小西弘晃, 嘉島 伸, 大澤資樹, Henrik Druid
    • Organizer
      第106次日本法医学会学術全国集会
    • Data Source
      KAKENHI-PROJECT-22K17411
  • [Presentation] 人工核酸導入Primerを用いた高感度メチル化解析と法医学的年齢推定2021

    • Author(s)
      磯崎翔太郎
    • Organizer
      日本DNA多型学会第30回学術集会
    • Data Source
      KAKENHI-PROJECT-19K19477
  • [Presentation] The assessment of cutaneous epithelium hypoxia in the murine frostbite model2021

    • Author(s)
      Shotaro Isozaki, Hiroki Tanaka, Kie Horioka, Hiroaki Konishi, Shin Kashima, Henrik Druid
    • Organizer
      第105次日本法医学会学術全国集会
    • Data Source
      KAKENHI-PROJECT-19K19477
  • [Presentation] The activation of Wnt signaling in the murine frostbite model2020

    • Author(s)
      Shotaro Isozaki, Hiroki Tanaka, Kie Horioka, Hiroaki Konishi, Shin Kashima, Henrik Druid
    • Organizer
      第104次日本法医学会学術全国集会
    • Data Source
      KAKENHI-PROJECT-19K19477
  • [Presentation] 乳酸菌由来長鎖ポリリン酸は血小板活性化を介して腸管上皮の創傷治癒を促進する2020

    • Author(s)
      磯崎翔太郎、藤谷幹浩、小西弘晃、田中宏樹、村上雄紀、杉山雄哉、 安藤勝祥、上野伸展、後藤拓磨、嘉島 伸、高氏修平、盛一健太郎、 田邊裕貴、水上裕輔、奥村利勝
    • Organizer
      第57回日本消化器免疫学会総会
    • Data Source
      KAKENHI-PROJECT-19K19477
  • [Presentation] PROBIOTIC-DERIVED POLYPHOSPHATE IMPROVES DAMAGED INTESTINAL EPITHELIA THROUGH INDUCING PLATELET-DERIVED CELL GROWTH MOLECULES2020

    • Author(s)
      Shotaro Isozaki , Mikihiro Fujiya , Hiroaki Konishi et al.
    • Organizer
      Digestive Disease Week 2020
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K19477
  • [Presentation] Primerへの人工核酸LNA導入によるCpG Islandにおける増幅効率改善効果の検討2019

    • Author(s)
      磯崎翔太郎, 小西弘晃
    • Organizer
      第88回日本法医学会学術関東地方集会
    • Data Source
      KAKENHI-PROJECT-19K19477
  • 1.  垣本 由布 (40734166)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 2.  上田 篤 (90728560)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 3.  UENO Nobuhiro
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results
  • 4.  藤谷 幹浩
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results
  • 5.  盛一 健太郎
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results
  • 6.  小西 弘晃
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 5 results

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