MIZUHARA MASAHIRO 水原正博

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Mizuhara Masahiro 水原正博

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Researcher Number	60845402
Other IDs
Affiliation (Current)	2025: 九州歯科大学, 歯学部, 助教
Affiliation (based on the past Project Information) *help	2025: 九州歯科大学, 歯学部, 助教 2020 – 2023: 九州歯科大学, 歯学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 57070:Developmental dentistry-related Except Principal Investigator Basic Section 57070:Developmental dentistry-related
Keywords	Principal Investigator VNUT / クロドロン酸 / アデノシン三リン酸 / 歯科矯正学 / 骨リモデリング / 疼痛 / ビスホスホネート / 小胞型ヌクレオチドトランスポーター Except Principal Investigator 歯根吸収 / FGFR2 … More / 顎下腺 / 分枝形態形成 / 上皮間葉相互作用 / Apert症候群 / 歯髄細胞 / VNUT / ATP / 幹細胞性 / 低酸素 / 歯髄幹細胞 / ＦＧＦ / 矯正学的歯の移動 / 歯根膜線維芽細胞 / ヒト歯根膜線維芽細胞 / FGF2 / FGF2（ｂFGF） / CAP / CEMP1 / メカニカルストレス / Piezo / Piezoチャネル / 疼痛 / 歯科矯正 / PIEZO Less

必須脂肪酸のエイコサペンタエン酸は矯正歯科治療における新規鎮痛薬となりうるか？Principal Investigator
- Principal Investigator
  
  水原正博
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57070:Developmental dentistry-related
- Research Institution
  Kyushu Dental College
矯正歯科治療時の歯根吸収におけるATPを介した新規制御機構の解明
- Principal Investigator
  
  郡司掛香織
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57070:Developmental dentistry-related
- Research Institution
  Kyushu Dental College
Apert症候群モデルマウスを用いた唾液分泌能および上皮間葉相互作用の解析
- Principal Investigator
  
  川元龍夫
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57070:Developmental dentistry-related
- Research Institution
  Kyushu Dental College
小胞型ヌクレオチドトランスポーター(VNUT)は骨リモデリングに関与するのか？Principal Investigator
- Principal Investigator
  
  水原正博
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 57070:Developmental dentistry-related
- Research Institution
  Kyushu Dental College
Elucidation of the mechanism of pain caused by tooth movement via Piezo channels
- Principal Investigator
  
  Sago Misa
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57070:Developmental dentistry-related
- Research Institution
  Kyushu Dental College
Basic research for development of prevention and treatment methods for root resorption applying bFGF
- Principal Investigator
  
  Kuroishi Kayoko
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57070:Developmental dentistry-related
- Research Institution
  Kyushu Dental College
Investigation of the development of pain during orthodontic tooth movement with adenosine triphosphatePrincipal Investigator
- Principal Investigator
  
  Mizuhara Masahiro
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 57070:Developmental dentistry-related
- Research Institution
  Kyushu Dental College

All 2024 2023 2022 2020

All Journal Article Presentation

[Journal Article] Ser252Trp mutation in fibroblast growth factor receptor 2 promotes branching morphogenesis in mouse salivary glands2024
- Author(s)
  Iwata Daiki、Kometani-Gunjigake Kaori、Nakao-Kuroishi Kayoko、Mizuhara Masahiro、Nakatomi Mitsushiro、Moriyama Keiji、Ono Kentaro、Kawamoto Tatsuo
- Journal Title
  
  Journal of Oral Biosciences
  
  Volume: 66 Issue: 1 Pages: 90-97
- DOI
  10.1016/j.job.2024.01.001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K10277
[Journal Article] PIEZO1 promotes ATP release from periodontal ligament cells following compression force2023
- Author(s)
  Horie Seiwa、Nakatomi Chihiro、Ito-Sago Misa、Morii Aoi、Orimoto Ai、Ikeda Hiroshi、Hsu Chia-Chien、Naniwa Mako、Mizuhara Masahiro、Gunjigake Kaori、Kawamoto Tatsuo、Ono Kentaro
- Journal Title
  
  European Journal of Orthodontics
  
  Volume: 45 Issue: 5 Pages: 565-574
- DOI
  10.1093/ejo/cjad052
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K09910, KAKENHI-PROJECT-21K10168
[Journal Article] Fibrillin-1 regulates periostin expression during maintenance of periodontal homeostasis.2022
- Author(s)
  Yoshikazu Manabe, Momotoshi Shiga, Kaori K Gunjigake, Kayoko Nakao-Kuroishi, Masahiro Mizuhara, Takashi Toyono, Yuji Seta, Tatsuo Kawamoto.
- Journal Title
  
  J Dent Sci.
  
  Volume: 17 Issue: 4 Pages: 1714-1721
- DOI
  10.1016/j.jds.2022.02.015
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K10253
[Journal Article] Vesicular nucleotide transporter mediates adenosine triphosphate release in compressed human periodontal ligament fibroblast cells and participates in tooth movement-induced nociception in rats.2020
- Author(s)
  Mizuhara M, Kometani-Gunjigake K, Nakao-Kuroishi K, Toyono T, Hitomi S, Morii A, Shiga M, Seta Y, Ono K, Kawamoto T.
- Journal Title
  
  Arch Oral Biol
  
  Volume: 11 Pages: 104607-104607
- DOI
  10.1016/j.archoralbio.2019.104607
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10059, KAKENHI-PROJECT-19K10391, KAKENHI-PROJECT-20K18789
[Presentation] 矯正歯科治療を想定した機械的刺激下のヒト歯根膜細胞におけるFGF-2を介したCEMP1、CAPの発現2024
- Author(s)
  力丸早紀子、黒石加代子、郡司掛香織、水原正博、川元龍夫
- Organizer
  第19回九州矯正歯科学会学術大会
- Data Source
  KAKENHI-PROJECT-21K10191
[Presentation] 低酸素下でのヒト歯髄幹細胞の特性変化2023
- Author(s)
  中垣優那、郡司掛香織、黒石加代子、水原正博、豊野孝、瀬田祐司、川元龍夫
- Organizer
  第18回九州矯正歯科学会
- Data Source
  KAKENHI-PROJECT-22K10253
[Presentation] 機械的刺激下のヒト歯根膜細胞におけるFGF-2を介したCEMP1、CAPの発現2023
- Author(s)
  力丸早紀子、黒石加代子、郡司掛香織、水原正博、川元龍夫
- Organizer
  第82回日本矯正歯科学会学術大会
- Data Source
  KAKENHI-PROJECT-21K10191
[Presentation] Apert症候群モデルマウスにおける胎生期顎下腺の形態学的解析2022
- Author(s)
  岩田大季、郡司掛香織、黒石加代子、水原正博、中富満城、小野堅太郎、川元龍夫
- Organizer
  第81回日本矯正歯科学会学術大会
- Data Source
  KAKENHI-PROJECT-22K10277
[Presentation] 低酸素下でのヒト歯髄幹細胞の性質の変化2022
- Author(s)
  梶原優那、郡司掛香織、黒石加代子、水原正博、豊野孝、瀬田祐司、川元龍夫
- Organizer
  第17回九州矯正歯科学会学術大会
- Data Source
  KAKENHI-PROJECT-22K10253
[Presentation] 低酸素下でのヒト歯髄幹細胞の性質の変化2022
- Author(s)
  中垣優那、郡司掛香織、黒石加代子、水原正博、豊野孝、瀬田祐司、川元龍夫
- Organizer
  第81回九州歯科学会総会・学術大会
- Data Source
  KAKENHI-PROJECT-22K10253

1. Kuroishi Kayoko (60468303)

# of Collaborated Projects: 4 results

# of Collaborated Products: 8 results
2. 川元龍夫 (50323704)

# of Collaborated Projects: 4 results

# of Collaborated Products: 8 results
3. 郡司掛香織 (90448811)

# of Collaborated Projects: 4 results

# of Collaborated Products: 8 results
4. Sago Misa (40815825)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 森井葵 (20882046)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 白川智彦 (50908225)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 小野堅太郎 (40316154)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 折本愛

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 瀬田祐司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 豊野孝

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

MIZUHARA MASAHIRO 水原 正博

Mizuhara Masahiro 水原 正博

Research Projects

Research Products

Co-Researchers

必須脂肪酸のエイコサペンタエン酸は矯正歯科治療における新規鎮痛薬となりうるか？Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

矯正歯科治療時の歯根吸収におけるATPを介した新規制御機構の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Apert症候群モデルマウスを用いた唾液分泌能および上皮間葉相互作用の解析

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

小胞型ヌクレオチドトランスポーター(VNUT)は骨リモデリングに関与するのか？Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the mechanism of pain caused by tooth movement via Piezo channels

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Basic research for development of prevention and treatment methods for root resorption applying bFGF

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Investigation of the development of pain during orthodontic tooth movement with adenosine triphosphatePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Ser252Trp mutation in fibroblast growth factor receptor 2 promotes branching morphogenesis in mouse salivary glands2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] PIEZO1 promotes ATP release from periodontal ligament cells following compression force2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Fibrillin-1 regulates periostin expression during maintenance of periodontal homeostasis.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Vesicular nucleotide transporter mediates adenosine triphosphate release in compressed human periodontal ligament fibroblast cells and participates in tooth movement-induced nociception in rats.2020

Author(s)

Journal Title

DOI

Data Source

[Presentation] 矯正歯科治療を想定した機械的刺激下のヒト歯根膜細胞におけるFGF-2を介したCEMP1、CAPの発現2024

Author(s)

Organizer

Data Source

[Presentation] 低酸素下でのヒト歯髄幹細胞の特性変化2023

Author(s)

Organizer

Data Source

[Presentation] 機械的刺激下のヒト歯根膜細胞におけるFGF-2を介したCEMP1、CAPの発現2023

Author(s)

Organizer

Data Source

[Presentation] Apert症候群モデルマウスにおける胎生期顎下腺の形態学的解析2022

MIZUHARA MASAHIRO 水原正博

Mizuhara Masahiro 水原正博