Kohno Hiroki 河野大輝

Researcher Number	60846773
Other IDs
Affiliation (Current)	2025: 東京大学, 大学院理学系研究科(理学部), 助教
Affiliation (based on the past Project Information) *help	2019 – 2024: 東京大学, 大学院理学系研究科(理学部), 助教
Review Section/Research Field	Principal Investigator Basic Section 45020:Evolutionary biology-related / Basic Section 44050:Animal physiological chemistry, physiology and behavioral biology-related / 0702:Biology at cellular to organismal levels, and related fields Except Principal Investigator Medium-sized Section 45:Biology at organismal to population levels and anthropology, and related fields / Sections That Are Subject to Joint Review: Basic Section45010:Genetics-related ,Basic Section45020:Evolutionary biology-related / Basic Section 45010:Genetics-related / Basic Section 45020:Evolutionary biology-related
Keywords	Principal Investigator ケニヨン細胞 / キノコ体 / セイヨウミツバチ / ゲノム編集 / 社会性行動 / ハチ目 / 進化発生学 / カブラハバチ / ノックイン / mKast … More Except Principal Investigator … More ケニヨン細胞 / キノコ体 / シングルセルRNA-seq / シロアリ / ミツバチ / 記憶・学習 / シングルセル RNA-seq解析 / ゴキブリ / 分子進化動態 / 脳 / ハチ目 Less

Analysis of molecular bases of evolution of Kenyon cell types in the brains of hymenopteran insects.
- Principal Investigator
  
  久保健雄
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 45020:Evolutionary biology-related
  Basic Section 45010:Genetics-related
  Sections That Are Subject to Joint Review: Basic Section45010:Genetics-related ,Basic Section45020:Evolutionary biology-related
- Research Institution
  The University of Tokyo
Analysis of molecular and neural basis of the brain correlated with behavioral characteristics of cockroaches
- Principal Investigator
  
  久保健雄
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 45:Biology at organismal to population levels and anthropology, and related fields
- Research Institution
  The University of Tokyo
進化発生学的解析によるハチ目のキノコ体の進化に寄与した分子基盤の解明Principal Investigator
- Principal Investigator
  
  河野大輝
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 45020:Evolutionary biology-related
- Research Institution
  The University of Tokyo
Development of a knock-in method and functional analysis of Kenyon cell subtypes in the mushroom bodies of the honey bee.Principal Investigator
- Principal Investigator
  
  Kohno Hiroki
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 44050:Animal physiological chemistry, physiology and behavioral biology-related
- Research Institution
  The University of Tokyo
Analyses of mKast functions for regulation of honeybee behavior using genome editing.Principal Investigator
- Principal Investigator
  
  Kohno Hiroki
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0702:Biology at cellular to organismal levels, and related fields
- Research Institution
  The University of Tokyo

All 2024 2023 2022 2021 2020 2019

All Journal Article Presentation

[Journal Article] Unique spatially and temporary-regulated/sex-specific expression of a long ncRNA, Nb-1, suggesting its pleiotropic functions associated with honey bee lifecycle.2024
- Author(s)
  Tadano H, Kohno H, Takeuchi H, Kubo T
- Journal Title
  
  Scientific Reports
  
  Volume: 14 Issue: 1 Pages: 8701-8701
- DOI
  10.1038/s41598-024-59494-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K18148, KAKENHI-PROJECT-23K05875
[Journal Article] Possible functions of ecdysone signaling reiteratively used in the adult honey bee brain.2023
- Author(s)
  Matsumura Y, Kohno H, and Kubo T
- Journal Title
  
  Frontiers in Bee Science
  
  Volume: 1 Pages: 1251714-1251714
- DOI
  10.3389/frbee.2023.1251714
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K18148, KAKENHI-PROJECT-23K05875
[Journal Article] Identification of ecdysone receptor target genes in the worker honey bee brains during foraging behavior.2023
- Author(s)
  Iino S, Oya S, Kakutani T, Kohno H, and Kubo T
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 10491-10491
- DOI
  10.1038/s41598-023-37001-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K18148, KAKENHI-PROJECT-23K05875
[Journal Article] Analysis of Antennal Responses to Motion Stimuli in the Honey Bee by Automated Tracking Using DeepLabCut.2023
- Author(s)
  Kohno H, Kamata S and Kubo T
- Journal Title
  
  Journal of Insect Behavior
  
  Volume: 36 Issue: 4 Pages: 332-346
- DOI
  10.1007/s10905-023-09845-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K18148, KAKENHI-PROJECT-23K05875
[Journal Article] Evolutionary dynamics of mushroom body Kenyon cell types in hymenopteran brains from multi-functional type to functionally specialized types.2023
- Author(s)
  Takayoshi Kuwabara, Hiroki Kohno, Masatsugu Hatakeyama, Takeo Kubo
- Journal Title
  
  Science Advances
  
  Volume: Add4210 Issue: 18
- DOI
  10.1126/sciadv.add4201
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03300, KAKENHI-PROJECT-20K15839, KAKENHI-PROJECT-23K05875, KAKENHI-PROJECT-22KJ0594
[Journal Article] Mblk-1/E93, an ecdysone related-transcription factor, targets synaptic plasticity-related genes in the honey bee mushroom bodies2022
- Author(s)
  Matsumura Yasuhiro、To Taiko Kim、Kunieda Takekazu、Kohno Hiroki、Kakutani Tetsuji、Kubo Takeo
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 21367-21367
- DOI
  10.1038/s41598-022-23329-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H00995, KAKENHI-PROJECT-20H03300, KAKENHI-PROJECT-20K15839
[Journal Article] ミツバチ脳における脱皮ホルモンシグナル関連転写因子Mblk-1の発現解析2021
- Author(s)
  松村泰宏、河野大輝、久保健雄
- Journal Title
  
  昆虫と自然
  
  Volume: 56 Pages: 30-33
- NAID
  40022469603
- Data Source
  KAKENHI-PROJECT-19K23740
[Journal Article] Developmental stage-specific distribution and phosphorylation of Mblk-1, a transcription factor involved in ecdysteroid-signaling in the honey bee brain2020
- Author(s)
  Kumagai Hitomi、Kunieda Takekazu、Nakamura Korefumi、Matsumura Yasuhiro、Namiki Manami、Kohno Hiroki、Kubo Takeo
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 8735-8735
- DOI
  10.1038/s41598-020-65327-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K15839, KAKENHI-PROJECT-20H03300, KAKENHI-PROJECT-19K23740
[Journal Article] ミツバチ脳における脱皮ホルモンシグナル関連転写因子Mblk-1の発現解析2020
- Author(s)
  松村泰宏、河野大輝、久保健雄
- Journal Title
  
  昆虫と自然
  
  Volume: 56 Pages: 30-33
- NAID
  40022469603
- Data Source
  KAKENHI-PROJECT-20K15839
[Journal Article] Genetics in the Honey Bee: Achievements and Prospects toward the Functional Analysis of Molecular and Neural Mechanisms Underlying Social Behaviors.2019
- Author(s)
  Kohno H , Kubo T
- Journal Title
  
  Insects
  
  Volume: 10 Issue: 10 Pages: 348-348
- DOI
  10.3390/insects10100348
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K23740
[Journal Article] ミツバチの社会性行動の分子生物学遺伝子から探るミツバチの脳の仕組み (特集ミツバチ新時代)2019
- Author(s)
  河野大輝 , 久保健雄
- Journal Title
  
  遺伝 : 生物の科学
  
  Volume: 73 Pages: 596-602
- NAID
  40022042698
- Data Source
  KAKENHI-PROJECT-19K23740
[Presentation] ミツバチの行動を司る脳基盤 -種間比較とゲノム編集によるアプローチ-2024
- Author(s)
  河野大輝
- Organizer
  第44回ミツバチ科学研究会
- Data Source
  KAKENHI-PROJECT-23K18148
[Presentation] ゲノム編集ミツバチの作出による成虫脳選択的に発現する遺伝子の機能解析2024
- Author(s)
  河野大輝
- Organizer
  日本昆虫学会第84回大会・第68回日本応用動物昆虫学会大会合同大会
- Data Source
  KAKENHI-PROJECT-23K05875
[Presentation] ミツバチのキノコ体を構成する新規ケニヨン細胞種の同定と解析2024
- Author(s)
  西川綾花、河野大輝、桑原嵩佳、久保健雄
- Organizer
  日本動物学会関東支部第76回大会
- Data Source
  KAKENHI-PROJECT-23K18148
[Presentation] ミツバチキノコ体ケニヨン細胞サブタイプの蛹期特異的な発生2024
- Author(s)
  鎌田周一、久保健雄、河野大輝
- Organizer
  日本動物学会関東支部第76回大会
- Data Source
  KAKENHI-PROJECT-23K05875
[Presentation] ミツバチキノコ体ケニヨン細胞サブタイプの蛹期特異的な発生2024
- Author(s)
  鎌田周一、久保健雄、河野大輝
- Organizer
  日本動物学会関東支部第76回大会
- Data Source
  KAKENHI-PROJECT-23K18148
[Presentation] ミツバチの行動を司る脳基盤 -種間比較とゲノム編集によるアプローチ-2024
- Author(s)
  河野大輝
- Organizer
  第44回ミツバチ科学研究会
- Invited
- Data Source
  KAKENHI-PROJECT-23K05875
[Presentation] ミツバチのキノコ体を構成する新規ケニヨン細胞種の同定と解析2024
- Author(s)
  西川綾花、河野大輝、桑原嵩佳、久保健雄
- Organizer
  日本動物学会関東支部第76回大会
- Data Source
  KAKENHI-PROJECT-23K05875
[Presentation] ゲノム編集ミツバチの作出による成虫脳選択的に発現する遺伝子の機能解析2023
- Author(s)
  河野大輝
- Organizer
  日本昆虫学会第84回大会・第68回日本応用動物昆虫学会大会合同大会
- Invited
- Data Source
  KAKENHI-PROJECT-23K18148
[Presentation] ハチ目における脳高次中枢キノコ体を構成するケニヨン細胞サブタイプの進化動態の解明2023
- Author(s)
  桑原嵩佳、河野大輝、畠山正統、久保健雄
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-23K05875
[Presentation] Application of scRNA-seq technology to explore the evolutionary dynamics of Kenyon cell types, which comprise the higher-order brain center, in Hymenoptera2023
- Author(s)
  Takayoshi Kuwabara, Hiroki Kohno, Masatsugu Hatakeyama, Takeo Kubo
- Organizer
  The CSHL Single Cell Analyses meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K05875
[Presentation] ミツバチのキノコ体ケニヨン細胞サブタイプの発生様式の解析2023
- Author(s)
  鎌田周一、河野大輝、久保健雄
- Organizer
  第22回東京大学生命科学シンポジウム
- Data Source
  KAKENHI-PROJECT-23K18148
[Presentation] Analyses of mKast functions in the mushroom bodies and optic lobes of the honey bee using knocked-out mutants produced by genome editing2023
- Author(s)
  Hiroki Kohno, Takeo Kubo
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-23K05875
[Presentation] ミツバチのキノコ体ケニヨン細胞サブタイプの発生様式の解析2023
- Author(s)
  鎌田周一、河野大輝、久保健雄
- Organizer
  第22回東京大学生命科学シンポジウム
- Data Source
  KAKENHI-PROJECT-23K05875
[Presentation] Analyses of mKast functions in the mushroom bodies and optic lobes of the honey bee using knocked-out mutants produced by genome editing2023
- Author(s)
  Hiroki Kohno, Takeo Kubo
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-23K18148
[Presentation] ハチ目昆虫の行動進化に伴い複雑化したケニヨン細胞タイプの進化動態解析2023
- Author(s)
  桑原嵩佳、河野大輝、畠山正統、久保健雄
- Organizer
  第34回高遠分子細胞生物学シンポジウム
- Data Source
  KAKENHI-PROJECT-23K18148
[Presentation] Analyses of mKast functions in the mushroom bodies and optic lobes of the honey bee using knocked-out mutants produced by genome editing2023
- Author(s)
  Hiroki Kohno, Takeo Kubo
- Organizer
  日本比較生理生化学会第45回大阪大会
- Data Source
  KAKENHI-PROJECT-23K05875
[Presentation] ハチ目昆虫の行動進化に伴い複雑化した脳キノコ体構成細胞の解析2023
- Author(s)
  桑原嵩佳、河野大輝、畠山正統、久保健雄
- Organizer
  生化学若い研究者の会第63回生命科学夏の学校
- Data Source
  KAKENHI-PROJECT-23K18148
[Presentation] ハチ目昆虫の行動進化に伴い複雑化した脳キノコ体構成細胞の解析2023
- Author(s)
  桑原嵩佳、河野大輝、畠山正統、久保健雄
- Organizer
  生化学若い研究者の会第63回生命科学夏の学校
- Data Source
  KAKENHI-PROJECT-23K05875
[Presentation] Application of scRNA-seq technology to explore the evolutionary dynamics of Kenyon cell types, which comprise the higher-order brain center, in Hymenoptera2023
- Author(s)
  Takayoshi Kuwabara, Hiroki Kohno, Masatsugu Hatakeyama, Takeo Kubo
- Organizer
  The CSHL Single Cell Analyses meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K18148
[Presentation] Investigation of the molecular basis of the development of Kenyon cell subtypes constituting the mushroom bodies of the honey bee brain2023
- Author(s)
  Shuichi Kamata, Takeo Kubo, Hiroki Kohno
- Organizer
  日本比較生理生化学会第45回大阪大会
- Data Source
  KAKENHI-PROJECT-23K18148
[Presentation] ハチ目昆虫の行動進化に伴い複雑化したケニヨン細胞タイプの進化動態解析2023
- Author(s)
  桑原嵩佳、河野大輝、畠山正統、久保健雄
- Organizer
  第34回高遠分子細胞生物学シンポジウム
- Data Source
  KAKENHI-PROJECT-23K05875
[Presentation] Investigation of the molecular basis of the development of Kenyon cell subtypes constituting the mushroom bodies of the honey bee brain2023
- Author(s)
  Shuichi Kamata, Takeo Kubo, Hiroki Kohno
- Organizer
  日本比較生理生化学会第45回大阪大会
- Data Source
  KAKENHI-PROJECT-23K05875
[Presentation] ハチ目における脳高次中枢キノコ体を構成するケニヨン細胞サブタイプの進化動態の解明2023
- Author(s)
  桑原嵩佳、河野大輝、畠山正統、久保健雄
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-23K18148
[Presentation] ミツバチのダンスコミュニケーションに関わる神経細胞種の探索　~ミツバチとマルハナバチの脳高次中枢の比較scRNA-seq解析~2022
- Author(s)
  桑原嵩佳、河野大輝、久保健雄
- Organizer
  シングルセルゲノミクス研究会2022
- Data Source
  KAKENHI-PROJECT-20K15839
[Presentation] 行動を司る脳進化の謎へ切り込む　~シンプルな脳を持つハチ目昆虫の種間比較解析より~2022
- Author(s)
  桑原嵩佳、河野大輝、畠山正統、久保健雄
- Organizer
  第7回ユニーク会
- Data Source
  KAKENHI-PROJECT-20K15839
[Presentation] Analysis and exploration of Kenyon cells increased with behavioral evolution in hymenopteran insects2022
- Author(s)
  Takayoshi Kuwabara, Hiroki Kohno, Masatsugu Hatakeyama, Takeo Kubo
- Organizer
  IUSSI2022 19th Congress of the International Union for the Study of Social Insects
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K15839
[Presentation] Identification of the pupal stages at which three Kenyon cell subtypes are generated in the mushroom bodies of the honey bee2022
- Author(s)
  Hiroki Kohno, Takeo Kubo
- Organizer
  日本発生生物学会第55回大会
- Data Source
  KAKENHI-PROJECT-20K15839
[Presentation] Functional analyses of mKast by producing knocked out worker honey bees using CRISPR/Cas92022
- Author(s)
  Hiroki Kohno, Takeo Kubo
- Organizer
  IUSSI2022 19th Congress of the International Union for the Study of Social Insects
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K15839
[Presentation] Functional analyses of mKast, which is preferentially expressed in middle-type Kenyon cells in mushroom bodies of the honey bee, by producing knocked-out workers2021
- Author(s)
  Hiroki Kohno, Takeo Kubo
- Organizer
  日本比較生理生化学会第43回札幌オンライン大会
- Data Source
  KAKENHI-PROJECT-20K15839
[Presentation] ゲノム編集によるミツバチの遺伝子機能解析2019
- Author(s)
  河野大輝
- Organizer
  ミツバチサミット2019
- Data Source
  KAKENHI-PROJECT-19K23740

1. 久保健雄 (10201469)

# of Collaborated Projects: 2 results

# of Collaborated Products: 14 results
2. 角谷徹仁

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kohno Hiroki 河野 大輝

Research Projects

Research Products

Co-Researchers

Analysis of molecular bases of evolution of Kenyon cell types in the brains of hymenopteran insects.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of molecular and neural basis of the brain correlated with behavioral characteristics of cockroaches

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

進化発生学的解析によるハチ目のキノコ体の進化に寄与した分子基盤の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of a knock-in method and functional analysis of Kenyon cell subtypes in the mushroom bodies of the honey bee.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analyses of mKast functions for regulation of honeybee behavior using genome editing.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Unique spatially and temporary-regulated/sex-specific expression of a long ncRNA, Nb-1, suggesting its pleiotropic functions associated with honey bee lifecycle.2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Possible functions of ecdysone signaling reiteratively used in the adult honey bee brain.2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Identification of ecdysone receptor target genes in the worker honey bee brains during foraging behavior.2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Analysis of Antennal Responses to Motion Stimuli in the Honey Bee by Automated Tracking Using DeepLabCut.2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Evolutionary dynamics of mushroom body Kenyon cell types in hymenopteran brains from multi-functional type to functionally specialized types.2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Mblk-1/E93, an ecdysone related-transcription factor, targets synaptic plasticity-related genes in the honey bee mushroom bodies2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] ミツバチ脳における脱皮ホルモンシグナル関連転写因子Mblk-1の発現解析2021

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Developmental stage-specific distribution and phosphorylation of Mblk-1, a transcription factor involved in ecdysteroid-signaling in the honey bee brain2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] ミツバチ脳における脱皮ホルモンシグナル関連転写因子Mblk-1の発現解析2020

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Genetics in the Honey Bee: Achievements and Prospects toward the Functional Analysis of Molecular and Neural Mechanisms Underlying Social Behaviors.2019

Kohno Hiroki 河野大輝

[Journal Article] ミツバチの社会性行動の分子生物学遺伝子から探るミツバチの脳の仕組み (特集ミツバチ新時代)2019