Kinugasa Yasuha 衣笠泰葉

Researcher Number	60852118
Other IDs	https://orcid.org/0000-0002-1119-1493
Affiliation (Current)	2025: 医療法人徳洲会野崎徳洲会病院(附属研究所), 研究所, 独立研究員
Affiliation (based on the past Project Information) *help	2025: 医療法人徳洲会野崎徳洲会病院(附属研究所), 研究所, 独立研究員 2023: 国立研究開発法人医薬基盤・健康・栄養研究所, 医薬基盤研究所ヘルス・メディカル微生物研究センター, 研究員 2022: 国立研究開発法人医薬基盤・健康・栄養研究所, 医薬基盤研究所ワクチン・アジュバント研究センター, 研究員 2019 – 2021: 広島大学, 原爆放射線医科学研究所, 助教
Review Section/Research Field	Principal Investigator Basic Section 48030:Pharmacology-related / Basic Section 43010:Molecular biology-related / 0701:Biology at molecular to cellular levels, and related fields Except Principal Investigator Medium-sized Section 63:Environmental analyses and evaluation and related fields
Keywords	Principal Investigator クロマチン / Rad51 / DNA損傷修復 / 相同組換え修復 / DNA損傷 / 核構造 / ラミン / イメージング / ESCRTIII / CLEM … More / 生細胞イメージング / 脂質 / 小胞体膜 / 核膜 / ESCRT-III / Lnp1 / Lem2 … More Except Principal Investigator ハイスループット解析技術 / バイオマーカー / 医療放射線 / ゲノムダメージ / 放射線被ばく Less

RNAウイルス感染におけるヒストン修飾を介した遺伝子発現制御機構Principal Investigator
- Principal Investigator
  
  衣笠泰葉
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 48030:Pharmacology-related
- Research Institution
  医療法人徳洲会野崎徳洲会病院(附属研究所)
Natural history of genome damage
- Principal Investigator
  
  田代聡
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 63:Environmental analyses and evaluation and related fields
- Research Institution
  Hiroshima University
The role of nucleoskeleton proteins in DNA damage repair foci formationPrincipal Investigator
- Principal Investigator
  
  Kinugasa Yasuha
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 43010:Molecular biology-related
- Research Institution
  National Institutes of Biomedical Innovation, Health and Nutrition
  Hiroshima University
Nuclear membrane maintenance by nuclear membrane protein Lem2 and Lnp1Principal Investigator
- Principal Investigator
  
  Kinugasa Yasuha
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0701:Biology at molecular to cellular levels, and related fields
- Research Institution
  Hiroshima University

All 2023 2022 2021 2020 2019

All Journal Article Presentation

[Journal Article] Klotho protects chromosomal DNA from radiation-induced damage2023
- Author(s)
  Nakayama Shinya、Sun Jiying、Horikoshi Yasunori、Kamimura Yoshitaka、Ike Takeshi、Fujino Shu、Kinugasa Yasuha、Sasaki Kensuke、Nakashima Ayumu、Masaki Takao、Tashiro Satoshi
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: online Issue: 5 Pages: 375-382
- DOI
  10.1093/jb/mvad001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K15017, KAKENHI-PROJECT-21H04927, KAKENHI-PROJECT-22K07212
[Journal Article] Post-Coronavirus Disease 2019 Syndrome in Japan: An Observational Study Using a Medical Database2023
- Author(s)
  Yasuha Kinugasa, Mara Anais Llamas-Covarrubias, Katsuhiko Ozaki, Yoshiaki Fujimura, Takeki Ohashi, Kou Fukuda, Shinichi Higashiue, Yusuke Nakamura, Yumiko Imai
- Journal Title
  
  JMA Journal
  
  Volume: 6 Issue: 4 Pages: 416-425
- DOI
  10.31662/jmaj.2023-0048
- ISSN
  2433-328X, 2433-3298
- Year and Date
  2023-10-16
- Language
  English
- Data Source
  KAKENHI-PROJECT-21K15017
[Journal Article] Inner nuclear membrane proteins Lem2 and Bqt4 interact with different lipid synthesis enzymes in fission yeast2023
- Author(s)
  Hirano Yasuhiro、Kinugasa Yasuha、Kubota Yoshino、Obuse Chikashi、Haraguchi Tokuko、Hiraoka Yasushi
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: online Issue: 1 Pages: 33-46
- DOI
  10.1093/jb/mvad017
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K15017, KAKENHI-PLANNED-20H05891, KAKENHI-PROJECT-19H03156, KAKENHI-PLANNED-18H05528, KAKENHI-PLANNED-18H05532, KAKENHI-PLANNED-18H05533, KAKENHI-PROJECT-23K05636, KAKENHI-PUBLICLY-22H05599, KAKENHI-PROJECT-20H00454, KAKENHI-PROJECT-23K23810
[Journal Article] 低線量放射線の生体影響2022
- Author(s)
  田代　聡、衣笠　泰葉
- Journal Title
  
  生体の科学
  
  Volume: 73 Pages: 154-157
- Data Source
  KAKENHI-PROJECT-21H04927
[Journal Article] A Combination of Iohexol Treatment and Ionizing Radiation Exposure Enhances Kidney Injury in Contrast-Induced Nephropathy by Increasing DNA Damage2022
- Author(s)
  Fujino Shu、Sun Jying、Nakayama Shinya、Horikoshi Yasunori、Kinugasa Yasuha、Ishida Mari、Sakai Chiemi、Ike Takeshi、Doi Shigehiro、Masaki Takao、Tashiro Satoshi
- Journal Title
  
  Radiation Research
  
  Volume: 197 Issue: 4 Pages: 384-395
- DOI
  10.1667/rade-21-00178.1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K15017, KAKENHI-PROJECT-22K07212, KAKENHI-PROJECT-21H04927
[Journal Article] Piwi-piRNA complexes induce stepwise changes in nuclear architecture at target loci2021
- Author(s)
  Iwasaki Yuka W、Sriswasdi Sira、Kinugasa Yasuha、Adachi Jun、Horikoshi Yasunori、Shibuya Aoi、Iwasaki Wataru、Tashiro Satoshi、Tomonaga Takeshi、Siomi Haruhiko
- Journal Title
  
  The EMBO Journal
  
  Volume: 40 Issue: 18
- DOI
  10.15252/embj.2021108345
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-19H05749, KAKENHI-PLANNED-19H05753, KAKENHI-PUBLICLY-21H00259, KAKENHI-PROJECT-21H04927, KAKENHI-PROJECT-21K15017, KAKENHI-PROJECT-16H06279
[Journal Article] Evaluating Individual Radiosensitivity for the Prediction of Acute Toxicities of Chemoradiotherapy in Esophageal Cancer Patients2020
- Author(s)
  Imano Nobuki、Nishibuchi Ikuno、Kawabata Emi、Kinugasa Yasuha、Shi Lin、Sakai Chiemi、Ishida Mari、Sakane Hiroaki、Akita Tomoyuki、Ishida Takafumi、Kimura Tomoki、Murakami Yuji、Tanaka Kimio、Horikoshi Yasunori、Sun Jiying、Nagata Yasushi、Tashiro Satoshi
- Journal Title
  
  Radiation Research
  
  Volume: 195 Issue: 3 Pages: 244-252
- DOI
  10.1667/rade-20-00234.1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15551, KAKENHI-PROJECT-18H03373, KAKENHI-PROJECT-17K16447, KAKENHI-PROJECT-19K23725, KAKENHI-PROJECT-21H04927, KAKENHI-PROJECT-20K08494, KAKENHI-PROJECT-19K07641
[Journal Article] Roles of Remote and Contact Forces in Epithelial Cell Structure Formation2020
- Author(s)
  Nakano Tadashi、Okaie Yutaka、Kinugasa Yasuha、Koujin Takako、Suda Tatsuya、Hiraoka Yasushi、Haraguchi Tokuko
- Journal Title
  
  Biophysical Journal
  
  Volume: 118 Issue: 6 Pages: 1466-1478
- DOI
  10.1016/j.bpj.2020.01.037
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-18H05528, KAKENHI-PLANNED-18H05533, KAKENHI-PROJECT-17H00733, KAKENHI-PROJECT-17H01444, KAKENHI-PROJECT-17H03636, KAKENHI-PROJECT-19K23725
[Journal Article] Lem2 and Lnp1 maintain the membrane boundary between the nuclear envelope and endoplasmic reticulum2020
- Author(s)
  Hirano Yasuhiro、Kinugasa Yasuha、Osakada Hiroko、Shindo Tomoko、Kubota Yoshino、Shibata Shinsuke、Haraguchi Tokuko、Hiraoka Yasushi
- Journal Title
  
  Communications Biology
  
  Volume: 3 Issue: 1 Pages: 276-276
- DOI
  10.1038/s42003-020-0999-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06489, KAKENHI-PLANNED-18H05528, KAKENHI-PLANNED-18H05533, KAKENHI-PROJECT-20H00454, KAKENHI-PROJECT-19K22389, KAKENHI-PROJECT-18K14840, KAKENHI-PROJECT-19K23725
[Journal Article] The very-long-chain fatty acid elongase Elo2 rescues lethal defects associated with loss of the nuclear barrier function in fission yeast cells2019
- Author(s)
  Kinugasa Yasuha、Hirano Yasuhiro、Sawai Megumi、Ohno Yusuke、Shindo Tomoko、Asakawa Haruhiko、Chikashige Yuji、Shibata Shinsuke、Kihara Akio、Haraguchi Tokuko、Hiraoka Yasushi
- Journal Title
  
  Journal of Cell Science
  
  Volume: 132 Issue: 10 Pages: 229021-229021
- DOI
  10.1242/jcs.229021
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06489, KAKENHI-PROJECT-19K06660, KAKENHI-PROJECT-19K23725, KAKENHI-PLANNED-18H05528, KAKENHI-PLANNED-18H05533, KAKENHI-PROJECT-17H01444, KAKENHI-PROJECT-17H03636
[Presentation] Lem2による核膜形態維持機構とゲノム安定化における役割2019
- Author(s)
  平野泰弘、衣笠泰葉、原口徳子、平岡泰
- Organizer
  第37回染色体ワークショップ・第18回細胞核ダイナミクス研究会
- Data Source
  KAKENHI-PROJECT-19K23725
[Presentation] Lem2と Lnp1は Vps4-ESCRT-III複合体の機能を制御することで核膜-小胞体構造を維持する2019
- Author(s)
  平野泰弘、衣笠泰葉、原口徳子、平岡泰
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K23725
[Presentation] Lem2 and Lnp1 cooperatively maintain the nuclear membrane integrity through ESCRT-III functions2019
- Author(s)
  Hirano Y, Kinugasa Y, Osakada H, Shindo T, Kubota Y, Shibata S, Haraguchi T, Hiraoka Y
- Organizer
  The International Fission Yeast Meeting 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K23725
[Presentation] Very-long-chain fatty acid elongase Elo2 rescues chromosomal defects associated with loss of nuclear membrane protein Lem22019
- Author(s)
  Kinugasa Y, Hirano Y, Asakawa H, Chikashige Y, Haraguchi T, Hiraoka Y
- Organizer
  The International Fission Yeast Meeting 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K23725

1. 田代聡 (20243610)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
2. 堀越保則 (00719429)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 粟井和夫 (30294573)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 西淵いくの (70595834)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 孫継英 (80397926)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 太田邦史 (90211789)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. HIRANO Yasuhiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
8. HARAGUCHI Tokuko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 今野伸樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kinugasa Yasuha 衣笠 泰葉

Research Projects

Research Products

Co-Researchers

RNAウイルス感染におけるヒストン修飾を介した遺伝子発現制御機構Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Natural history of genome damage

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The role of nucleoskeleton proteins in DNA damage repair foci formationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Nuclear membrane maintenance by nuclear membrane protein Lem2 and Lnp1Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Klotho protects chromosomal DNA from radiation-induced damage2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Post-Coronavirus Disease 2019 Syndrome in Japan: An Observational Study Using a Medical Database2023

Author(s)

Journal Title

DOI

ISSN

Year and Date

Language

Data Source

[Journal Article] Inner nuclear membrane proteins Lem2 and Bqt4 interact with different lipid synthesis enzymes in fission yeast2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 低線量放射線の生体影響2022

Author(s)

Journal Title

Data Source

[Journal Article] A Combination of Iohexol Treatment and Ionizing Radiation Exposure Enhances Kidney Injury in Contrast-Induced Nephropathy by Increasing DNA Damage2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Piwi-piRNA complexes induce stepwise changes in nuclear architecture at target loci2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Evaluating Individual Radiosensitivity for the Prediction of Acute Toxicities of Chemoradiotherapy in Esophageal Cancer Patients2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Roles of Remote and Contact Forces in Epithelial Cell Structure Formation2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Lem2 and Lnp1 maintain the membrane boundary between the nuclear envelope and endoplasmic reticulum2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The very-long-chain fatty acid elongase Elo2 rescues lethal defects associated with loss of the nuclear barrier function in fission yeast cells2019

Author(s)

Journal Title

DOI

Data Source

Kinugasa Yasuha 衣笠泰葉