takahashi jyunichi 高橋純一

… Alternative Names

Takahashi Junichi 高橋純一

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Researcher Number	60869569
Affiliation (Current)	2025: 九州大学, 医学研究院, 共同研究員
Affiliation (based on the past Project Information) *help	2023: 九州大学, 医学研究院, 共同研究員 2020 – 2022: 九州大学, 大学病院, 医員
Review Section/Research Field	Principal Investigator Basic Section 55020:Digestive surgery-related / Basic Section 50020:Tumor diagnostics and therapeutics-related
Keywords	Principal Investigator BAP1 / ドラッグリポジショニング / 肝内胆管癌 / リポジショニング・ドラッグ / 分子鎖アミノ酸（BCAA）活性 / 多層オミックス解析 / BCAT1/BCAT2 / mTOR / BCAA / 代謝産物 … More / オミックス解析 / AI(機械学習)創薬 / リポジショニング薬 / リポジショニング / 遺伝子変異 / 創薬 Less

肝内胆管癌多層オミックス解析と機械学習によるリポジショニング薬の同定Principal Investigator
- Principal Investigator
  
  高橋純一
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Kyushu University
Identification of repositioning drugs targeting BAP1 mutation specific to intrahepatic cholangiocarcinoma.Principal Investigator
- Principal Investigator
  
  Takahashi Junichi
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Kyushu University

All 2024 2023 2022 2021 2020

All Journal Article Presentation

[Journal Article] Tumor suppressive role of the epigenetic master regulator BRD3 in colorectal cancer.2024
- Author(s)
  Hashimoto M, Masuda T, Nakano Y, Tobo T, Saito H, Koike K, Takahashi J, Abe T, Ando Y, Ozato Y, Hosoda K, Higuchi S, Hisamatsu Y, Toshima T, Yonemura Y, Hata T, Uemura M, Eguchi H, Doki Y, Mori M, Mimori K.
- Journal Title
  
  Cancer Sci.
  
  Volume: - Issue: 6 Pages: 7538-7548
- DOI
  10.1111/cas.16129
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08826, KAKENHI-PROJECT-22K08894, KAKENHI-PROJECT-22K09006, KAKENHI-PROJECT-23K08215, KAKENHI-PROJECT-21K07179, KAKENHI-PROJECT-23K24164
[Journal Article] Successful multidisciplinary treatment with complete response to atezolizumab plus bevacizumab in a 90-year-old patient with hepatocellular carcinoma recurrence.2023
- Author(s)
  Hosoda K, Toshima T, Takahashi J, Yonemura Y, Hisamatsu Y, Hirose K, Masuda T, Motomura Y, Abe T, Ando Y, Dairaku K, Nakano Y, Hashimoto M, Hiraki Y, Soejima Y, Yoshizumi T, Mimori K.
- Journal Title
  
  Int Cancer Conf J.
  
  Volume: 12(4) Issue: 4 Pages: 274-278
- DOI
  10.1007/s13691-023-00618-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K07774, KAKENHI-PROJECT-22K08826, KAKENHI-PROJECT-22K08894, KAKENHI-PROJECT-23K08215, KAKENHI-PROJECT-21K07179, KAKENHI-PROJECT-23K24164
[Journal Article] Identification of the Minimum Combination of Serum microRNAs to Predict the Recurrence of Colorectal Cancer Cases.2023
- Author(s)
  Yoshikawa Y, Fukunaga M, Takahashi J, Shimizu D, Masuda T, Mizushima T, Yamada K, Mori M, Eguchi H, Doki Y, Ochiya T, Mimori K.
- Journal Title
  
  Ann Surg Oncol.
  
  Volume: 30(1) Issue: 1 Pages: 233-243
- DOI
  10.1245/s10434-022-12355-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07179, KAKENHI-PROJECT-22K08826, KAKENHI-PROJECT-22K09006, KAKENHI-PROJECT-23K24164
[Journal Article] Transducin Beta-Like 2 is a Potential Driver Gene that Adapts to Endoplasmic Reticulum Stress to Promote Tumor Growth of Lung Adenocarcinoma.2023
- Author(s)
  Kosai K, Masuda T, Kitagawa A, Tobo T, Ono Y, Ando Y, Takahashi J, Haratake N, Kohno M, Takenaka T, Yoshizumi T, Mimori K.
- Journal Title
  
  Ann Surg Oncol.
  
  Volume: 30(12) Issue: 12 Pages: 7538-7548
- DOI
  10.1245/s10434-023-13864-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K08826, KAKENHI-PROJECT-22K09006, KAKENHI-PROJECT-22K16572
[Journal Article] Convergent genomic diversity and novel BCAA metabolism in intrahepatic cholangiocarcinoma2023
- Author(s)
  Kitagawa A, Osawa T,Noda M,Kobayashi Y, Aki S,Nakano Y,Saito T,Shimizu D,Komatsu H,Sugaya M,Takahashi J,...Mimori K.
- Journal Title
  
  Br J Cancer
  
  Volume: - Issue: 12 Pages: 22068-22068
- DOI
  10.1038/s41416-023-02256-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08826, KAKENHI-PROJECT-20H04281, KAKENHI-PROJECT-20K07260, KAKENHI-PROJECT-20K21832, KAKENHI-PUBLICLY-22H04839, KAKENHI-PROJECT-23K18234, KAKENHI-PROJECT-22K07774, KAKENHI-PROJECT-22K09006, KAKENHI-PROJECT-21K08745, KAKENHI-PLANNED-23H04938, KAKENHI-PROJECT-22H04925, KAKENHI-PROJECT-23K24164
[Journal Article] Fanconi Anemia Complementation Group E, a DNA Repair-Related Gene, Is a Potential Marker of Poor Prognosis in Hepatocellular Carcinoma.2022
- Author(s)
  Takahashi J, Masuda T, Kitagawa A, Tobo T, Nakano Y, Abe T, Ando Y, Kosai K, Kobayashi Y, Matsumoto Y, Yoshizumi T, Mori M, Mimori K.
- Journal Title
  
  Oncology.
  
  Volume: 100(2) Issue: 2 Pages: 101-113
- DOI
  10.1159/000520582
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09176, KAKENHI-PROJECT-19K09220, KAKENHI-PUBLICLY-20H05039, KAKENHI-PROJECT-19H03715, KAKENHI-PROJECT-22K08826, KAKENHI-PROJECT-22K09006, KAKENHI-PROJECT-20K08960, KAKENHI-PROJECT-23K24164
[Presentation] 24 網羅的ハブ遺伝子解析に基づく肝細胞癌におけるハブ遺伝子MFSD10発現の臨床的意義(会議録)2022
- Author(s)
  高橋純一(九州大学病院別府病院外科), 増田隆明, 橋本雅弘, 中野祐輔, 大楽勝司, 阿部正, 斉藤秀幸, 大里祐樹, 安東由貴, 中野貴文, 久松雄一, 戸島剛男, 米村祐輔, 吉住朋晴, 三森功士
- Organizer
  第122回日本外科学会定期学術集
- Data Source
  KAKENHI-PROJECT-22K08826
[Presentation] BAP1変異を有する肝内胆管癌（ICC）に有効なリポジショニング化合物の同定2022
- Author(s)
  高橋純一
- Organizer
  第31回日本癌病態治療研究会
- Data Source
  KAKENHI-PROJECT-20K16416
[Presentation] 肝内胆管癌における新規ドライバー遺伝子NTSR1の同定とその臨床的意義2022
- Author(s)
  内田博喜(中津市立中津市民病院外科), 北川彰洋, 高橋純一, 梅田健二, 江頭明典, 折田博之, 増田隆明, 三森功士
- Organizer
  第122回日本外科学会定期学術集
- Data Source
  KAKENHI-PROJECT-22K08826
[Presentation] 肝細胞癌でのDNA修復関連遺伝子FANCE発現の臨床的意義の研究2021
- Author(s)
  高橋純一、増田隆明、北川彰洋、内田博喜、森　正樹、三森功士
- Organizer
  第8回　がんと代謝研究会 in 佐渡
- Data Source
  KAKENHI-PROJECT-20K16416
[Presentation] FA経路遺伝子の一つであるFANCEは肝細胞癌診断の有望なバイオマーカーとなりうる2020
- Author(s)
  高橋純一、増田隆明、北川彰洋、小林雄太、高尾誠一朗、本村有史、安東由貴、大津甫、武石一樹、米村祐輔、森正樹、三森功士
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K16416
[Presentation] 肝細胞癌(HCC)におけるDNA修復関連遺伝子FANCE高発現の臨床的意義2020
- Author(s)
  高橋純一、増田隆明、北川彰洋、小林雄太、倉光正太郎、松本佳大、大津　甫、内田博喜、森　正樹、三森功士
- Organizer
  第75回日本消化器外科学会総会
- Data Source
  KAKENHI-PROJECT-20K16416
[Presentation] DNA修復関連遺伝子FANCEの高発現は肝細胞癌において予後不良マーカーである2020
- Author(s)
  高橋純一、増田隆明、北川彰洋、中野貴文、小斎啓祐、小林雄太、倉光正太郎、藤井昌志、野田美和、鶴田祐介、松本佳大、大津　甫、黒田陽介、内田博喜、森　正樹、三森功士
- Organizer
  第120回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-20K16416

1. 三森功士 (50322748)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
2. 岩田通夫 (60746642)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 本村有史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 増田隆明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

takahashi jyunichi 高橋 純一

Takahashi Junichi 高橋 純一

Research Projects

Research Products

Co-Researchers

肝内胆管癌多層オミックス解析と機械学習によるリポジショニング薬の同定Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification of repositioning drugs targeting BAP1 mutation specific to intrahepatic cholangiocarcinoma.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Tumor suppressive role of the epigenetic master regulator BRD3 in colorectal cancer.2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Successful multidisciplinary treatment with complete response to atezolizumab plus bevacizumab in a 90-year-old patient with hepatocellular carcinoma recurrence.2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Identification of the Minimum Combination of Serum microRNAs to Predict the Recurrence of Colorectal Cancer Cases.2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Transducin Beta-Like 2 is a Potential Driver Gene that Adapts to Endoplasmic Reticulum Stress to Promote Tumor Growth of Lung Adenocarcinoma.2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Convergent genomic diversity and novel BCAA metabolism in intrahepatic cholangiocarcinoma2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Fanconi Anemia Complementation Group E, a DNA Repair-Related Gene, Is a Potential Marker of Poor Prognosis in Hepatocellular Carcinoma.2022

Author(s)

Journal Title

DOI

Data Source

[Presentation] 24 網羅的ハブ遺伝子解析に基づく肝細胞癌におけるハブ遺伝子MFSD10発現の臨床的意義(会議録)2022

Author(s)

Organizer

Data Source

[Presentation] BAP1変異を有する肝内胆管癌（ICC）に有効なリポジショニング化合物の同定2022

Author(s)

Organizer

Data Source

[Presentation] 肝内胆管癌における新規ドライバー遺伝子NTSR1の同定とその臨床的意義2022

Author(s)

Organizer

Data Source

[Presentation] 肝細胞癌でのDNA修復関連遺伝子FANCE発現の臨床的意義の研究2021

Author(s)

Organizer

Data Source

[Presentation] FA経路遺伝子の一つであるFANCEは肝細胞癌診断の有望なバイオマーカーとなりうる2020

Author(s)

Organizer

Data Source

[Presentation] 肝細胞癌(HCC)におけるDNA修復関連遺伝子FANCE高発現の臨床的意義2020

Author(s)

Organizer

Data Source

[Presentation] DNA修復関連遺伝子FANCEの高発現は肝細胞癌において予後不良マーカーである2020

Author(s)

Organizer

Data Source

takahashi jyunichi 高橋純一

Takahashi Junichi 高橋純一