Yamazaki Hiroya 山崎啓也

Researcher Number	60888105
Other IDs
Affiliation (Current)	2025: 東京大学, 大学院理学系研究科(理学部), 助教
Affiliation (based on the past Project Information) *help	2021 – 2025: 東京大学, 大学院理学系研究科(理学部), 助教
Review Section/Research Field	Principal Investigator Basic Section 43030:Functional biochemistry-related / Transformative Research Areas, Section (III)
Keywords	Principal Investigator トランスポゾン / 相分離 / piRNA / 生殖細胞 / メチル化 / 生殖顆粒 / 液液相分離

Research Projects
(3 results)
Research Products
(9 results)

メゾ複雑体顆粒による生殖細胞のゲノムインテグリティ維持機構の解明Principal Investigator
- Principal Investigator
  
  山崎啓也
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  The University of Tokyo
生殖細胞でのトランスポゾン抑制において低流動性顆粒がH3K9me3を保護する機構の解明Principal Investigator
- Principal Investigator
  
  山崎啓也
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 43030:Functional biochemistry-related
- Research Institution
  The University of Tokyo
Analysis of the function of arginine methylation of the RNA helicase Vasa in germ granule formation and localizationPrincipal Investigator
- Principal Investigator
  
  Yamazaki Hiroya
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 43030:Functional biochemistry-related
- Research Institution
  The University of Tokyo

All 2023 2022 2021

All Journal Article Presentation

[Journal Article] Bombyx Vasa sequesters transposon mRNAs in nuage via phase separation requiring RNA binding and self-association2023
- Author(s)
  Yamazaki Hiroya、Namba Yurika、Kuriyama Shogo、Nishida Kazumichi M.、Kajiya Asako、Siomi Mikiko C.
- Journal Title
  
  Nature Communications
  
  Volume: 14 Issue: 1 Pages: 1942-1942
- DOI
  10.1038/s41467-023-37634-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K15039, KAKENHI-PROJECT-19H05466
[Journal Article] Cell cycle-specific phase separation regulated by protein charge blockiness2022
- Author(s)
  Yamazaki H、Takagi M、Kosako H、Hirano T、Yoshimura SH.
- Journal Title
  
  Nature Cell Biology
  
  Volume: - Issue: 5 Pages: 625-632
- DOI
  10.1038/s41556-022-00903-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K15039, KAKENHI-PROJECT-20K06628, KAKENHI-PROJECT-20K06649, KAKENHI-PLANNED-20H05938, KAKENHI-PROJECT-18H05276
[Presentation] Charge block-driven liquid-liquid phase separation and its regulation by mitotic protein phosphorylation 電荷ブロック駆動型液 - 液相分離とタンパク質リン酸化によるその制御2023
- Author(s)
  Yamazaki H、Takagi M、Kosako H、Hirano T、Yoshimura SH.
- Organizer
  日本放射線影響学会第66回大会
- Invited
- Data Source
  KAKENHI-PROJECT-23K14141
[Presentation] 電荷ブロックによる液液相分離のメカニズムとその細胞分裂期タンパク質リン酸化による制御2023
- Author(s)
  Yamazaki H、Takagi M、Kosako H、Hirano T、Yoshimura SH.
- Organizer
  第96回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-23K14141
[Presentation] Germline-specific DEAD-box RNA helicase Vasa sequesters transposon mRNAs in nuage via phase separation requiring RNA binding and self-association2023
- Author(s)
  Yamazaki H, Namba Y, Kuriyama S, Nishida KM, Kajiya A, Siomi MC.
- Organizer
  The 28th Annual Meeting of the RNA Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K14141
[Presentation] Characterization of the germline-specific DEAD-box RNA helicase Vasa in LLPS-mediated formation of germ granules2022
- Author(s)
  Yamazaki H, Namba Y, Nishida KM, Murakami R, Kuriyama S, Kajiya A, Siomi MC.
- Organizer
  第23回日本RNA学会年会
- Data Source
  KAKENHI-PROJECT-21K15039
[Presentation] Characterization of DEAD-box RNA helicase Vasa in LLPS-mediated nuage formation in ovarian germ cells2021
- Author(s)
  Yamazaki H, Nishida KM, Murakami R, Kuriyama S, Kajiya A, Siomi MC.
- Organizer
  第22回日本RNA学会年会
- Data Source
  KAKENHI-PROJECT-21K15039
[Presentation] Characterization of the DEAD-box RNA helicase Vasa in LLPS-mediated formation of germ granules2021
- Author(s)
  Yamazaki H, Nishida KM, Murakami R, Kuriyama S, Kajiya A, Siomi MC.
- Organizer
  EMBL Symposium: The Non-Coding Genome
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K15039
[Presentation] Characterization of the DEAD-box RNA helicase Vasa in LLPS-mediated formation of germ granule, which is the piRNA biogenesis center in ovarian germ cells2021
- Author(s)
  Yamazaki H, Nishida KM, Murakami R, Kuriyama S, Kajiya A, Siomi MC.
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K15039

Yamazaki Hiroya 山崎 啓也

Research Projects

Research Products

メゾ複雑体顆粒による生殖細胞のゲノムインテグリティ維持機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

生殖細胞でのトランスポゾン抑制において低流動性顆粒がH3K9me3を保護する機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of the function of arginine methylation of the RNA helicase Vasa in germ granule formation and localizationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Bombyx Vasa sequesters transposon mRNAs in nuage via phase separation requiring RNA binding and self-association2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cell cycle-specific phase separation regulated by protein charge blockiness2022

Author(s)

Journal Title

DOI

Data Source

[Presentation] Charge block-driven liquid-liquid phase separation and its regulation by mitotic protein phosphorylation 電荷ブロック駆動型液 - 液相分離とタンパク質リン酸化によるその制御2023

Author(s)

Organizer

Data Source

[Presentation] 電荷ブロックによる液液相分離のメカニズムとその細胞分裂期タンパク質リン酸化による制御2023

Author(s)

Organizer

Data Source

[Presentation] Germline-specific DEAD-box RNA helicase Vasa sequesters transposon mRNAs in nuage via phase separation requiring RNA binding and self-association2023

Author(s)

Organizer

Data Source

[Presentation] Characterization of the germline-specific DEAD-box RNA helicase Vasa in LLPS-mediated formation of germ granules2022

Author(s)

Organizer

Data Source

[Presentation] Characterization of DEAD-box RNA helicase Vasa in LLPS-mediated nuage formation in ovarian germ cells2021

Author(s)

Organizer

Data Source

[Presentation] Characterization of the DEAD-box RNA helicase Vasa in LLPS-mediated formation of germ granules2021

Author(s)

Organizer

Data Source

[Presentation] Characterization of the DEAD-box RNA helicase Vasa in LLPS-mediated formation of germ granule, which is the piRNA biogenesis center in ovarian germ cells2021

Author(s)

Organizer

Data Source

Yamazaki Hiroya 山崎啓也