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Yamazaki Hiroya  山崎 啓也

ORCIDConnect your ORCID iD *help
Researcher Number 60888105
Other IDs
Affiliation (Current) 2025: 東京大学, 大学院理学系研究科(理学部), 助教
Affiliation (based on the past Project Information) *help 2021 – 2025: 東京大学, 大学院理学系研究科(理学部), 助教
Review Section/Research Field
Principal Investigator
Basic Section 43030:Functional biochemistry-related / Transformative Research Areas, Section (III)
Keywords
Principal Investigator
トランスポゾン / 相分離 / piRNA / 生殖細胞 / メチル化 / 生殖顆粒 / 液液相分離
  • Research Projects

    (3 results)
  • Research Products

    (9 results)
  •  メゾ複雑体顆粒による生殖細胞のゲノムインテグリティ維持機構の解明Principal Investigator

    • Principal Investigator
      山崎 啓也
    • Project Period (FY)
      2024 – 2025
    • Research Category
      Grant-in-Aid for Transformative Research Areas (A)
    • Review Section
      Transformative Research Areas, Section (III)
    • Research Institution
      The University of Tokyo
  •  生殖細胞でのトランスポゾン抑制において低流動性顆粒がH3K9me3を保護する機構の解明Principal Investigator

    • Principal Investigator
      山崎 啓也
    • Project Period (FY)
      2023 – 2024
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 43030:Functional biochemistry-related
    • Research Institution
      The University of Tokyo
  •  Analysis of the function of arginine methylation of the RNA helicase Vasa in germ granule formation and localizationPrincipal Investigator

    • Principal Investigator
      Yamazaki Hiroya
    • Project Period (FY)
      2021 – 2022
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 43030:Functional biochemistry-related
    • Research Institution
      The University of Tokyo

All 2023 2022 2021

All Journal Article Presentation

  • [Journal Article] Bombyx Vasa sequesters transposon mRNAs in nuage via phase separation requiring RNA binding and self-association2023

    • Author(s)
      Yamazaki Hiroya、Namba Yurika、Kuriyama Shogo、Nishida Kazumichi M.、Kajiya Asako、Siomi Mikiko C.
    • Journal Title

      Nature Communications

      Volume: 14 Issue: 1 Pages: 1942-1942

    • DOI

      10.1038/s41467-023-37634-2

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K15039, KAKENHI-PROJECT-19H05466
  • [Journal Article] Cell cycle-specific phase separation regulated by protein charge blockiness2022

    • Author(s)
      Yamazaki H、Takagi M、Kosako H、Hirano T、Yoshimura SH.
    • Journal Title

      Nature Cell Biology

      Volume: - Issue: 5 Pages: 625-632

    • DOI

      10.1038/s41556-022-00903-1

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K15039, KAKENHI-PROJECT-20K06628, KAKENHI-PROJECT-20K06649, KAKENHI-PLANNED-20H05938, KAKENHI-PROJECT-18H05276
  • [Presentation] Charge block-driven liquid-liquid phase separation and its regulation by mitotic protein phosphorylation 電荷ブロック駆動型液 - 液相分離とタンパク質リン酸化によるその制御2023

    • Author(s)
      Yamazaki H、Takagi M、Kosako H、Hirano T、Yoshimura SH.
    • Organizer
      日本放射線影響学会第66回大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-23K14141
  • [Presentation] 電荷ブロックによる液液相分離のメカニズムとその細胞分裂期タンパク質リン酸化による制御2023

    • Author(s)
      Yamazaki H、Takagi M、Kosako H、Hirano T、Yoshimura SH.
    • Organizer
      第96回日本生化学会大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-23K14141
  • [Presentation] Germline-specific DEAD-box RNA helicase Vasa sequesters transposon mRNAs in nuage via phase separation requiring RNA binding and self-association2023

    • Author(s)
      Yamazaki H, Namba Y, Kuriyama S, Nishida KM, Kajiya A, Siomi MC.
    • Organizer
      The 28th Annual Meeting of the RNA Society
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K14141
  • [Presentation] Characterization of the germline-specific DEAD-box RNA helicase Vasa in LLPS-mediated formation of germ granules2022

    • Author(s)
      Yamazaki H, Namba Y, Nishida KM, Murakami R, Kuriyama S, Kajiya A, Siomi MC.
    • Organizer
      第23回日本RNA学会年会
    • Data Source
      KAKENHI-PROJECT-21K15039
  • [Presentation] Characterization of DEAD-box RNA helicase Vasa in LLPS-mediated nuage formation in ovarian germ cells2021

    • Author(s)
      Yamazaki H, Nishida KM, Murakami R, Kuriyama S, Kajiya A, Siomi MC.
    • Organizer
      第22回日本RNA学会年会
    • Data Source
      KAKENHI-PROJECT-21K15039
  • [Presentation] Characterization of the DEAD-box RNA helicase Vasa in LLPS-mediated formation of germ granules2021

    • Author(s)
      Yamazaki H, Nishida KM, Murakami R, Kuriyama S, Kajiya A, Siomi MC.
    • Organizer
      EMBL Symposium: The Non-Coding Genome
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K15039
  • [Presentation] Characterization of the DEAD-box RNA helicase Vasa in LLPS-mediated formation of germ granule, which is the piRNA biogenesis center in ovarian germ cells2021

    • Author(s)
      Yamazaki H, Nishida KM, Murakami R, Kuriyama S, Kajiya A, Siomi MC.
    • Organizer
      第44回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-21K15039

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