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ZHANG XU  張 旭

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Zhang Xu  張 旭

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Researcher Number 60892669
Affiliation (Current) 2025: 国際医療福祉大学, トランスレーショナルニューロサイエンスリサーチセンター, 特任助教
Affiliation (based on the past Project Information) *help 2024: 国際医療福祉大学, トランスレーショナルニューロサイエンスリサーチセンター, 特任助教
2021 – 2023: 国際医療福祉大学, トランスレーショナルニューロサイエンスセンター, 特任助教
Review Section/Research Field
Principal Investigator
Basic Section 52020:Neurology-related
Except Principal Investigator
Basic Section 52020:Neurology-related
Keywords
Principal Investigator
ランビエ絞輪 / 脱髄疾患 / 抗神経抗体 / 視神経脊髄炎 / 多発性硬化症 / 神経内科疾患 / 脱髄 / 神経免疫疾患 / 自己抗体 / Juxta-paranode … More / 自己免疫性ノドパチー / IgG4 / satellite glia / 後根神経節 / LGI4 / ノド抗体 / 慢性炎症性脱髄性多発神経炎 … More
Except Principal Investigator
自己抗体 / 慢性炎症性脱髄性多発神経炎 / 神経免疫疾患 / ノド抗体 / ランビエ絞輪 / 視神経脊髄炎 / 多発性硬化症 / 脱髄疾患 / peripheral nerve / node of Ranvier / autoantibody / demyelinaiton / multiple sclerosis Less
  • Research Projects

    (3 results)
  • Research Products

    (6 results)
  • Co-Researchers

    (10 People)
  •  Discovery of novel nodal antibodies in the central nervous system demyelinating diseases and elucidation of the mechanisms through an optic nerve demyelination modelPrincipal Investigator

    • Principal Investigator
      張 旭
    • Project Period (FY)
      2023 – 2024
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 52020:Neurology-related
    • Research Institution
      International University of Health and Welfare
  •  Elucidation of mechanisms of central and peripheral nervous system demyelination caused by newly discovered anti-nodal antibodies in autoimmune nodopathy

    • Principal Investigator
      吉良 潤一
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52020:Neurology-related
    • Research Institution
      International University of Health and Welfare
  •  Discovery of novel anti-LGI4 antibodies in chronic demyelinating polyneuropathy and elucidation of its mechanismPrincipal Investigator

    • Principal Investigator
      Zhang Xu
    • Project Period (FY)
      2021 – 2022
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 52020:Neurology-related
    • Research Institution
      International University of Health and Welfare

All 2023 2022 2021

All Journal Article Presentation

  • [Journal Article] Anti-LGI4 antibody is a novel juxtaparanodal autoantibody for chronic inflammatory demyelinating polyneuropathy2023

    • Author(s)
      Zhang X, Kira J, Ogata H, Imamura T, Mitsuishi M, Fujii T, Kobayashi M, Kitagawa K, Namihira Y, Ohya Y, Maimaitijiang G, Yamasaki R, Fukata Y, Fukata M, Isobe N, Nakamura Y.
    • Journal Title

      Neurology Neuroimmunology and Neuroinflammation

      Volume: 10(2) Issue: 2 Pages: 1-13

    • DOI

      10.1212/nxi.0000000000200081

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K07467, KAKENHI-PROJECT-21K19390, KAKENHI-PROJECT-22K15717, KAKENHI-PROJECT-20H00459, KAKENHI-PROJECT-20K16602, KAKENHI-PROJECT-21K15700, KAKENHI-PROJECT-21K15703, KAKENHI-PROJECT-20K22910, KAKENHI-PROJECT-23K23986, KAKENHI-PROJECT-23K18266, KAKENHI-PROJECT-22K07499
  • [Presentation] Clinical features and mechanism of LGI4-IgG4-positive inflammatory demyelinating polyneuropathy2022

    • Author(s)
      Xu Zhang, Jun-ichi Kira, Hidenori Ogata, Ayako Sakoda, Masaki Kobayashi, Kazuo Kitagawa, Yukihiro Namihira, Yusuke Ohya, Tomohiro Imamura, Guzailiayi Maimaitijiang, Ryo Yamasaki, Noriko Isobe, Yuri Nakamura
    • Organizer
      第63回日本神経学会学術大会
    • Data Source
      KAKENHI-PROJECT-21K15703
  • [Presentation] LGI4-IgG4はLGI4とADAM22の蛋白間相互作用を阻害して脱髄を起こすCIDPの新たなノド抗体である.2021

    • Author(s)
      張旭、緒方英紀、今村友裕、藤井敬之、山崎亮、磯部紀子、吉良潤一
    • Organizer
      第33回日本神経免疫学会学術集会
    • Data Source
      KAKENHI-PROJECT-21K15703
  • [Presentation] LGI4 is a novel autoantigen for nodopathy/paranodopathy type chronic inflammatory demyelinating polyneuropath2021

    • Author(s)
      Xu Zhang, Hidenori Ogata, Tomohiro Imamura, Takayuki Fujii, Ryo Yamasaki, Jun-ichi Kira
    • Organizer
      American Neurological Association 2021
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K15703
  • [Presentation] IgG4抗LGI4抗体はランビエ絞輪juxta-paranodeを標的とするCIDPの新たな自己抗体である.2021

    • Author(s)
      張旭、緒方英紀、今村友裕、藤井敬之、山崎亮、磯部紀子、吉良潤一
    • Organizer
      第32回日本末梢神経学会学術集会
    • Data Source
      KAKENHI-PROJECT-21K15703
  • [Presentation] LGI4 is a novel autoantigen for nodopathy type chronic inflammatory demyelinating polyneuropathy.2021

    • Author(s)
      Xu Zhang, Hidenori Ogata, Tomohiro Imamura, Takayuki Fujii, Ryo Yamasaki, Jun-ichi Kira
    • Organizer
      The 62nd Annual Meeting of the Japanese Society of Neurology
    • Data Source
      KAKENHI-PROJECT-21K15703
  • 1.  吉良 潤一 (40183305)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 2.  矢口 貴博 (30434947)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  今村 友裕 (30725122)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 4.  藤井 敬之 (30822481)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  中村 優理 (40822375)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 6.  磯部 紀子 (60452752)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  真崎 勝久 (90612903)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 8.  緒方 英紀 (90778838)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  Maimaitijiang Guzailiayi (60887107)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 10.  山崎 亮
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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