taniai tomohiko 谷合智彦

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Taniai Tomohiko 谷合智彦

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Researcher Number	60961860
Other IDs
Affiliation (Current)	2025: 東京慈恵会医科大学, 医学部, 助教
Affiliation (based on the past Project Information) *help	2022 – 2025: 東京慈恵会医科大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 55020:Digestive surgery-related / 0901:Oncology and related fields Except Principal Investigator Basic Section 55020:Digestive surgery-related / Basic Section 55010:General surgery and pediatric surgery-related
Keywords	Principal Investigator 酸性セラミダーゼ / 産生セラミダーゼ / リン脂質代謝 / 肝転移 / 膵臓癌 / VETC / MYC / 癌免疫微小環境 / 複合免疫療法 / 癌微小環境 / 肝細胞癌 … More Except Principal Investigator … More 肝細胞癌 / 癌微小環境 / オートファジー / 膵臓癌 / 血管新生阻害薬 / microRNA / エクソソーム / 血管内皮細胞 / 癌免疫 / レンバチニブ / 薬剤耐性 / 分子標的薬 / マイトファジー / レンバチニブ耐性 / リキッドバイオプシー / 獲得耐性メカニズム / ミトコンドリア / ライソゾーム / 肝癌 / GPR15 / 複合免疫療法 / MHCクラスI / 腫瘍免疫 / 免疫回避機構 / Lysosome酵素 Less

肝癌におけるGPR15の分子生物学的機能解明および革新的癌免疫療法の開発
- Principal Investigator
  
  堀内尭
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Jikei University School of Medicine
肝細胞癌におけるライソゾームとミトコンドリアの関連に注目した革新的治療法の開発
- Principal Investigator
  
  坂本太郎
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Jikei University School of Medicine
Elucidation of mechanisms of chemotherapy resistance through epigenetic analysis of pancreatic cancer and development of innovative treatment methods
- Principal Investigator
  
  宇和川匡
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Jikei University School of Medicine
癌微小環境に着目した肝細胞癌の分子標的薬耐性メカニズム解明と革新的治療法の開発
- Principal Investigator
  
  恩田真二
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Jikei University School of Medicine
肝細胞癌の宿主免疫回避機構の解明に基づく新たな治療戦略の開発
- Principal Investigator
  
  池上徹
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Jikei University School of Medicine
肝癌微小環境における癌関連血管内皮細胞の分子生物学的機能解明と革新的治療法開発
- Principal Investigator
  
  春木孝一郎
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Jikei University School of Medicine
リン脂質代謝酵素酸性セラミダーゼに着目した膵癌肝転移の機序解明と革新的治療法開発Principal Investigator
- Principal Investigator
  
  谷合智彦
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Jikei University School of Medicine
Analysis of lysosome enzymes in pancreatic cancer specific immune evasion system
- Principal Investigator
  
  白井祥睦
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Jikei University School of Medicine
  University of Toyama
免疫微小環境を標的とした高悪性度肝細胞癌に対する統合的治療戦略の開発
- Principal Investigator
  
  古川賢英
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Jikei University School of Medicine
The tumor microenvironment and the novel therapy of MYC-associated hepatocellular carcinomaPrincipal Investigator
- Principal Investigator
  
  Taniai Tomohiko
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0901:Oncology and related fields
- Research Institution
  Jikei University School of Medicine

All 2024 2023 2022

All Journal Article Presentation

[Journal Article] Identification and clinical implications of endogenous retrovirus elements suppressed by SETDB1 in hepatocellular carcinoma2024
- Author(s)
  Igarashi Y, Akiyama Y, Shimada S, Watanabe S, Hatano M, Kodera K, Okazaki K, Tanji Y, Tsukihara S, Taniai T, Nara A, Yamane M, Kamachi A, Umemura K, Yasukawa K, Ono H, Akahoshi K, Tanabe M, Haruki K, Furukawa K, Ikegami T, Tanaka S.
- Journal Title
  
  JHEP Reports
  
  Volume: 7 Issue: 3 Pages: 101307-101307
- DOI
  10.1016/j.jhepr.2024.101307
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K27670, KAKENHI-PROJECT-24K02320, KAKENHI-PROJECT-24K11898
[Journal Article] Short-term Outcomes of Laparoscopic<i>Versus</i>Open Liver Resection in the Elderly: A Propensity Score-matched Analysis2024
- Author(s)
  IGARASHI YOSUKE、HARUKI KOICHIRO、FURUKAWA KENEI、TANIAI TOMOHIKO、YANAGAKI MITSURU、OKUI NORIMITSU、SHIRAI YOSHIHIRO、TSUNEMATSU MASASHI、SAKAMOTO TARO、IKEGAMI TORU
- Journal Title
  
  Anticancer Research
  
  Volume: 44 Issue: 6 Pages: 2731-2736
- DOI
  10.21873/anticanres.17081
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24K11920
[Journal Article] Proposal for Prognosis-Oriented Definition of Borderline Resectable Hepatocellular Carcinoma.2024
- Author(s)
  Haruki K, Harimoto N, Furukawa K, Taniai T, Yanagaki M, Igarashi Y, Tsunematsu M, Shirai Y, Shirabe K, Ikegami T
- Journal Title
  
  J Am Coll Surg.
  
  Volume: 238 Issue: 6 Pages: 1137-1147
- DOI
  10.1097/xcs.0000000000001032
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24K11898, KAKENHI-PROJECT-24K11920
[Journal Article] The postoperative platelet-to-lymphocyte ratio predicts the outcome of patients undergoing pancreaticoduodenectomy for pancreatic head cancer2023
- Author(s)
  Shirai Yoshihiro、Hamura Ryoga、Tanji Yoshiaki、Taniai Tomohiko、Yanagaki Mitsuru、Haruki Koichiro、Furukawa Kenei、Onda Shinji、Sakamoto Taro、Gocho Takeshi、Ikegami Toru
- Journal Title
  
  Surgery Today
  
  Volume: 54 Issue: 3 Pages: 247-257
- DOI
  10.1007/s00595-023-02727-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K08202
[Journal Article] Open Thoracic Drainage Followed by Proximal Splenic Artery Embolization for Massive Hydrothorax Before Living Donor Liver Transplantation2023
- Author(s)
  Taniai Tomohiko、Haruki Koichiro、Furukawa Kenei、Yanagaki Mitsuru、Hamura Ryoga、Akaoka Munetoshi、Tsunematsu Masashi、Onda Shinji、Shirai Yoshihiro、Uwagawa Tadashi、Ikegami Toru
- Journal Title
  
  Transplantation Proceedings
  
  Volume: 55 Issue: 4 Pages: 884-887
- DOI
  10.1016/j.transproceed.2023.03.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08805, KAKENHI-PROJECT-22K20804
[Journal Article] Multimodal Management for Refractory Biliary Stricture After Living Donor Liver Transplantation2023
- Author(s)
  Taniai Tomohiko、Furukawa Kenei、Haruki Koichiro、Yanagaki Mitsuru、Hamura Ryoga、Akaoka Munetoshi、Tsunematsu Masashi、Onda Shinji、Shirai Yoshihiro、Uwagawa Tadashi、Ikegami Toru
- Journal Title
  
  Transplantation Proceedings
  
  Volume: 55 Issue: 4 Pages: 940-944
- DOI
  10.1016/j.transproceed.2023.04.001
- Data Source
  KAKENHI-PROJECT-22K20804
[Journal Article] Dynamics of the prognostic nutritional index in preoperative chemotherapy in patients with colorectal liver metastases.2023
- Author(s)
  Taniai T, Furukawa K, Igarashi Y, Shirai Y, Haruki K, Onda S, Iwase R, Matsumoto M, Fujioka S, Ikegami T.
- Journal Title
  
  Surg Oncol.
  
  Volume: 49 Pages: 101966-101966
- DOI
  10.1016/j.suronc.2023.101966
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08718, KAKENHI-PROJECT-22K20804
[Journal Article] Superior mesenteric vein/portal vein contact in preoperative imaging indicates biological malignancy in anatomically resectable pancreatic cancer2023
- Author(s)
  Shirai Yoshihiro、Onda Shinji、Tanji Yoshiaki、Hamura Ryoga、Matsumoto Michinori、Yanagaki Mitsuru、Tsunematsu Masashi、Taniai Tomohiko、Haruki Kochiro、Furukawa Kenei、Abe Kyohei、Sakamoto Taro、Gocho Takeshi、Uwagawa Tadashi、Ikegami Toru
- Journal Title
  
  Surgical Oncology
  
  Volume: 51 Pages: 101998-101998
- DOI
  10.1016/j.suronc.2023.101998
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K08202
[Presentation] Vessels encapsulating tumor clusters陽性肝細胞癌の免疫細胞プロファイリング2024
- Author(s)
  谷合智彦，春木孝一郎，古川賢英，柳垣充，赤岡宗紀，恩田真二，白井祥睦，丹治芳明，五十嵐陽介，羽村凌雅，衛藤謙，池上徹
- Organizer
  第124回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-23K08222
[Presentation] 肝細胞癌切除例におけるオステオぺニア合併椎体骨折の臨床的意義2024
- Author(s)
  春木孝一郎，古川賢英，赤岡宗紀，柳垣　充，谷合智彦，恩田真二，奥井紀光，松本倫典，白井祥睦，池上　徹
- Organizer
  第124回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-24K11920
[Presentation] 肝細胞癌血管内皮細胞の細胞外小胞を介した腫瘍微小環境における相互作用の解析2024
- Author(s)
  柳垣　充，赤岡宗紀，春木孝一郎，古川賢英，谷合智彦，石崎俊太，奥井紀光，松本倫典，坂本太郎，後町武志，池上　徹
- Organizer
  第60回日本肝癌研究会
- Data Source
  KAKENHI-PROJECT-24K11920
[Presentation] 肝細胞癌における異常血管構造と癌微小環境免疫細胞に基づいた予後予測分類2024
- Author(s)
  谷合智彦，春木孝一郎，古川賢英，柳垣充，五十嵐陽介，白井祥睦，松本倫典，坂本太郎，後町武志，池上徹
- Organizer
  第22回日本消化器外科学会大会
- Data Source
  KAKENHI-PROJECT-23K08222
[Presentation] Vessels encapsulating tumor clusters is a poor prognostic factor in non-viral hepatocellular carcinoma2024
- Author(s)
  Tomohiko Taniai, Koichiro Haruki, Kenei Furukawa, Mitsuru Yanagaki, Munetoshi Akaoka, Norimitsu Okui, Michinori Matsumoto, Taro Sakamoto, Takeshi Gocho, Toru Ikegami
- Organizer
  第36回日本肝胆膵外科学会学術集会
- Data Source
  KAKENHI-PROJECT-23K08222
[Presentation] 肝細胞癌におけるPARK9阻害はミトコンドリア機能不全とフェロトーシスを誘導する2024
- Author(s)
  柳垣充，赤岡宗紀，春木孝一郎，古川賢英，谷合智彦，白井祥睦，奥井紀光，松本倫典，坂本太郎，後町武志，池上　徹
- Organizer
  第22回日本消化器外科学会大会
- Data Source
  KAKENHI-PROJECT-24K11920
[Presentation] MTM/VETC陽性肝がんの癌免疫微小環境及び臨床的特徴とマウスモデルを用いた免疫チェックポイント阻害剤の奏功2023
- Author(s)
  谷合智彦，島田周，春木孝一郎，秋山好光，五十嵐陽介，丹治芳明，古川賢英，後町武志，池上徹，田中真二
- Organizer
  第78回日本消化器外科学会総会
- Data Source
  KAKENHI-PROJECT-23K08222
[Presentation] 癌微小環境に着目した進行肝細胞癌に対する免疫療法2023
- Author(s)
  谷合智彦，島田周，秋山好光，丹治芳明，赤星径一，池上徹，田中真二
- Organizer
  第21回日本消化器外科学会大会
- Data Source
  KAKENHI-PROJECT-22K20804
[Presentation] 解剖学的切除可能膵癌におけるSMV/PV接触の生物学的意義2023
- Author(s)
  白井祥睦, 丹治芳明, 羽村凌雅, 後町武志, 恒松雅, 奥井紀光, 塩崎弘憲, 阿部恭平, 松本倫典, 坂本太郎, 五十嵐陽介, 谷合智彦, 柳垣充, 赤岡宗紀, 山畑勇統, 春木孝一郎, 安田淳吾, 古川賢英, 恩田真二, 池上徹
- Organizer
  JDDW2023
- Data Source
  KAKENHI-PROJECT-23K08202
[Presentation] Vessels encapsulating tumor clusters陽性肝細胞癌の臨床病理学的特徴と複合免疫療法奏功の可能性2023
- Author(s)
  谷合智彦，春木孝一郎，古川賢英，白井祥睦，安田淳吾，恩田真二，恒松雅，五十嵐陽介，坂本太郎，後町武志，松本倫典，池上徹
- Organizer
  第55回制癌剤適応研究会
- Data Source
  KAKENHI-PROJECT-22K20804
[Presentation] 癌微小環境に着目した高悪性度肝細胞癌の分子生物学的特徴及び免疫療法の奏功2023
- Author(s)
  谷合智彦，島田周，秋山好光，樺嶋綾乃，下川雅弘，丹治芳明，五十嵐陽介，月原秀，春木孝一郎，赤星径一，池上徹，田邊稔，大木隆生，田中真二
- Organizer
  第123回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-22K20804
[Presentation] The clinical significance and tumor microenvironment of vessels encapsulating tumor clusters (VETC)-positive hepatocellular carcinoma.2023
- Author(s)
  Tomohiko Taniai, Koichiro Haruki, Kenei Furukawa, Mitsuru Yanagaki, Muneetoshi Akaoka, Toru Ikegami.
- Organizer
  AASLD The Liver Meeting 2023.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K08222
[Presentation] The clinical significance and tumor microenvironment of vessels encapsulating tumor clusters (VETC)-positive hepatocellular carcinoma.2023
- Author(s)
  Tomohiko Taniai, Koichiro Haruki, Kenei Furukawa, Mitsuru Yanagaki, Muneetoshi Akaoka, Toru Ikegami
- Organizer
  AASLD The Liver Meeting 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K20804
[Presentation] MTM/VETC陽性肝がんの癌免疫微小環境及び臨床的特徴とマウスモデルを用いた免疫チェックポイント阻害剤の奏功2023
- Author(s)
  谷合智彦，島田周，春木孝一郎，秋山好光，五十嵐陽介，丹治芳明，古川賢英，後町武志，池上徹，田中真二．
- Organizer
  第78回日本消化器外科学会総会
- Data Source
  KAKENHI-PROJECT-22K20804
[Presentation] 予後不良型肝細胞癌における免疫微小環境の解明と免疫療法奏効の検討2022
- Author(s)
  谷合智彦，島田周，秋山好光，樺島綾乃，下川雅弘，田中真二
- Organizer
  第33回日本消化器癌発生学会総会
- Data Source
  KAKENHI-PROJECT-22K20804
[Presentation] 肝細胞癌におけるVETC/MTMの臨床的意義とマウスモデルを用いた免疫療法奏功の検討2022
- Author(s)
  谷合智彦，島田周，秋山好光，椛島綾乃，下川雅弘，八木宏平，赤星径一，春木孝一郎，田邊稔，池上徹，田中真二
- Organizer
  第60回日本癌治療学会学術集会
- Data Source
  KAKENHI-PROJECT-22K20804

1. 白井祥睦 (10785364)

# of Collaborated Projects: 8 results

# of Collaborated Products: 11 results
2. 春木孝一郎 (60720894)

# of Collaborated Projects: 8 results

# of Collaborated Products: 15 results
3. 池上徹 (80432938)

# of Collaborated Projects: 8 results

# of Collaborated Products: 15 results
4. 古川賢英 (80624973)

# of Collaborated Projects: 8 results

# of Collaborated Products: 15 results
5. 柳垣充 (80979435)

# of Collaborated Projects: 7 results

# of Collaborated Products: 8 results
6. 恩田真二 (10459620)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
7. 羽村凌雅 (60894425)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
8. 奥井紀光 (60648864)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. 安田淳吾 (90896870)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. 嶋田洋太 (20560824)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 田中晴祥 (80793504)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 戸島剛男 (40608965)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 吉住朋晴 (80363373)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
14. 堀内尭 (00838774)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 恒松雅 (70912757)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 坂本太郎 (60366234)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 宇和川匡 (70287209)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 高橋数冴 (00909385)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 藤田雄 (10737133)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 秋山好光

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 波多野恵

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 田中真二

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 島田周

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

taniai tomohiko 谷合 智彦

Taniai Tomohiko 谷合 智彦

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リン脂質代謝酵素酸性セラミダーゼに着目した膵癌肝転移の機序解明と革新的治療法開発Principal Investigator

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The tumor microenvironment and the novel therapy of MYC-associated hepatocellular carcinomaPrincipal Investigator

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[Journal Article] Identification and clinical implications of endogenous retrovirus elements suppressed by SETDB1 in hepatocellular carcinoma2024

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[Journal Article] Short-term Outcomes of Laparoscopic<i>Versus</i>Open Liver Resection in the Elderly: A Propensity Score-matched Analysis2024

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[Journal Article] Proposal for Prognosis-Oriented Definition of Borderline Resectable Hepatocellular Carcinoma.2024

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[Journal Article] The postoperative platelet-to-lymphocyte ratio predicts the outcome of patients undergoing pancreaticoduodenectomy for pancreatic head cancer2023

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[Journal Article] Open Thoracic Drainage Followed by Proximal Splenic Artery Embolization for Massive Hydrothorax Before Living Donor Liver Transplantation2023

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taniai tomohiko 谷合智彦

Taniai Tomohiko 谷合智彦