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Sonehara Kyuto  曽根原 究人

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曽根原 究人  ソネハラ キュウト

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Researcher Number 60975358
Other IDs
Affiliation (Current) 2025: 東京大学, 大学院医学系研究科(医学部), 客員研究員
Affiliation (based on the past Project Information) *help 2025: 東京大学, 大学院医学系研究科(医学部), 助教
2023: 東京大学, 大学院医学系研究科(医学部), 助教
Review Section/Research Field
Principal Investigator
Basic Section 48040:Medical biochemistry-related
Keywords
Principal Investigator
全ゲノムシーケンス / 構造多型 / ゲノムワイド関連解析 / ロングリードシーケンス / 遺伝統計学
  • Research Projects

    (2 results)
  • Research Products

    (12 results)
  • Co-Researchers

    (1 People)
  •  ロングリード技術を用いたMHC領域の構造多様性・機能的意義解明Principal Investigator

    • Principal Investigator
      曽根原 究人
    • Project Period (FY)
      2025 – 2026
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 48040:Medical biochemistry-related
    • Research Institution
      The University of Tokyo
  •  Genome-wide elucidation of disease susceptibility structural variation using short- and long-read sequencingPrincipal Investigator

    • Principal Investigator
      曽根原 究人
    • Project Period (FY)
      2023 – 2024
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 48040:Medical biochemistry-related
    • Research Institution
      The University of Tokyo

All 2024 2023

All Journal Article Presentation

  • [Journal Article] Genetic drivers of heterogeneity in type 2 diabetes pathophysiology2024

    • Author(s)
      Suzuki Ken、Hatzikotoulas Konstantinos、Southam Lorraine、Taylor Henry J.、Yin Xianyong、Lorenz Kim M.、Mandla Ravi、Huerta-Chagoya Alicia、Melloni Giorgio E. M.、Kanoni Stavroula、Rayner Nigel W.、Bocher Ozvan、Arruda Ana Luiza、Sonehara Kyuto et al.
    • Journal Title

      Nature

      Volume: 627 Issue: 8003 Pages: 347-357

    • DOI

      10.1038/s41586-024-07019-6

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K14451, KAKENHI-PROJECT-21H04850, KAKENHI-PROJECT-21H03206
  • [Journal Article] Genome-wide association study identifies risk loci within the major histocompatibility complex region for Hunner-type interstitial cystitis2023

    • Author(s)
      Akiyama Y、Sonehara K、Maeda D、Katoh H、Naito T、Yamamoto K、Morisaki T、Ishikawa S、Ushiku T、Kume H、Homma Y、Okada Y
    • Journal Title

      Cell Reports Medicine

      Volume: 4 Issue: 7 Pages: 101114-101114

    • DOI

      10.1016/j.xcrm.2023.101114

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K16788, KAKENHI-PROJECT-23K14451, KAKENHI-PROJECT-22K07538, KAKENHI-PROJECT-22H00476
  • [Journal Article] Extracting immunological and clinical heterogeneity across autoimmune rheumatic diseases by cohort-wide immunophenotyping2023

    • Author(s)
      Tanaka Hiroaki、Okada Yukinori、Nakayamada Shingo、Miyazaki Yusuke、Sonehara Kyuto et al.
    • Journal Title

      Annals of the Rheumatic Diseases

      Volume: 83 Issue: 2 Pages: 242-252

    • DOI

      10.1136/ard-2023-224537

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K14451, KAKENHI-PROJECT-22H00476, KAKENHI-PROJECT-23K24465
  • [Journal Article] Pan-cancer and cross-population genome-wide association studies dissect shared genetic backgrounds underlying carcinogenesis2023

    • Author(s)
      Sato Go、Shirai Yuya、Namba Shinichi、Edahiro Ryuya、Sonehara Kyuto et al.
    • Journal Title

      Nature Communications

      Volume: 14 Issue: 1 Pages: 3671-3671

    • DOI

      10.1038/s41467-023-39136-7

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K14451, KAKENHI-PROJECT-22K07538, KAKENHI-PROJECT-23K08128, KAKENHI-PROJECT-22H00476
  • [Journal Article] Reconstruction of the personal information from human genome reads in gut metagenome sequencing data2023

    • Author(s)
      Tomofuji Yoshihiko、Sonehara Kyuto et al.
    • Journal Title

      Nature Microbiology

      Volume: 8 Issue: 6 Pages: 1079-1094

    • DOI

      10.1038/s41564-023-01381-3

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K14451, KAKENHI-PROJECT-22H00476
  • [Journal Article] Estimating gene-level false discovery probability improves eQTL statistical fine-mapping precision2023

    • Author(s)
      Wang Qingbo S、Edahiro Ryuya、Namkoong Ho、Hasegawa Takanori、Shirai Yuya、Sonehara Kyuto et al.
    • Journal Title

      NAR Genomics and Bioinformatics

      Volume: 5 Issue: 4

    • DOI

      10.1093/nargab/lqad090

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K14451
  • [Journal Article] Single-cell analyses and host genetics highlight the role of innate immune cells in COVID-19 severity2023

    • Author(s)
      Japan COVID-19 Task Force
    • Journal Title

      Nature Genetics

      Volume: 55 Issue: 5 Pages: 753-767

    • DOI

      10.1038/s41588-023-01375-1

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K16624, KAKENHI-PROJECT-23K14451, KAKENHI-PROJECT-22K08283, KAKENHI-PROJECT-23K11300, KAKENHI-PROJECT-21K09068, KAKENHI-PROJECT-22K15493, KAKENHI-PROJECT-22H00476, KAKENHI-PROJECT-23K27671
  • [Journal Article] Analysis of gut microbiome, host genetics, and plasma metabolites reveals gut microbiome-host interactions in the Japanese population2023

    • Author(s)
      Tomofuji Yoshihiko、Kishikawa Toshihiro、Sonehara Kyuto et al.
    • Journal Title

      Cell Reports

      Volume: 42 Issue: 11 Pages: 113324-113324

    • DOI

      10.1016/j.celrep.2023.113324

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K14451, KAKENHI-PROJECT-21K08344, KAKENHI-PROJECT-22H00476
  • [Presentation] Genome-wide association and HLA fine-mapping analysis of Hunner-type interstitial cystitis identify predisposing class II HLA variants.2023

    • Author(s)
      Kyuto Sonehara, Yoshiyuki Akiyama, Daichi Maeda, Hiroto Katoh, Tatsuhiko Naito, Kenichi Yamamoto, Biobank Japan Project, Takayuki Morisaki, Shumpei Ishikawa, Tetsuo Ushiku, Haruki Kume, Yukio Homma, Yukinori Okada
    • Organizer
      The 14th International Workshop on Advanced Genomics
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K14451
  • [Presentation] 頭蓋内胚細胞腫瘍のゲノムワイド関連解析は遺伝的背景の解明を通じ 、病因と疫学の理解に貢献する2023

    • Author(s)
      曽根原 究人, 木村 由依, 中野 嘉子, 小澤 達也, 藤井 隆司, 富山 新太, 鈴木 智成, 山口 秀, 三輪 点, 大江 直行, 深井 順也, 河村 淳史, 市村 幸一, 西川 亮, 岡田 随象, 寺島 慶太
    • Organizer
      第82回日本癌学会学術総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-23K14451
  • [Presentation] Genome-wide association and HLA fine-mapping analysis of Hunner-type interstitial cystitis identify predisposing class II HLA variants.2023

    • Author(s)
      Kyuto Sonehara, Yoshiyuki Akiyama, Daichi Maeda, Hiroto Katoh, Tatsuhiko Naito, Kenichi Yamamoto, Biobank Japan Project, Takayuki Morisaki, Shumpei Ishikawa, Tetsuo Ushiku, Haruki Kume, Yukio Homma, Yukinori Okada
    • Organizer
      The American Society of Human Genetics Annual Meeting 2023
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K14451
  • [Presentation] Genome-wide association and HLA fine-mapping analysis of Hunner-type interstitial cystitis identify risk HLA variants.2023

    • Author(s)
      Kyuto Sonehara, Yoshiyuki Akiyama, Daichi Maeda, Hiroto Katoh, Tatsuhiko Naito, Kenichi Yamamoto, Biobank Japan Project, Takayuki Morisaki, Shumpei Ishikawa, Tetsuo Ushiku, Haruki Kume, Yukio Homma, Yukinori Okada
    • Organizer
      Human Genetics Asia 2023
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K14451
  • 1.  秋山 佳之
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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