Sonehara Kyuto 曽根原究人

… Alternative Names

曽根原究人ソネハラキュウト

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Researcher Number	60975358
Other IDs
Affiliation (Current)	2025: 東京大学, 大学院医学系研究科(医学部), 客員研究員
Affiliation (based on the past Project Information) *help	2025: 東京大学, 大学院医学系研究科(医学部), 客員研究員 2023: 東京大学, 大学院医学系研究科(医学部), 助教
Review Section/Research Field	Principal Investigator Basic Section 48040:Medical biochemistry-related Except Principal Investigator Basic Section 56030:Urology-related
Keywords	Principal Investigator 構造多型 / ロングリードシーケンス / 遺伝統計学 / MHC領域 / HLA遺伝子 / 全ゲノムシーケンス / ゲノムワイド関連解析 Except Principal Investigator シングルセル解析 / 全ゲノム関連解析 / リピドミクス解析 / オミクス解析 / ハンナ型間質性膀胱炎

横断的オミクス解析と機械学習による間質性膀胱炎の治療標的とバイオマーカーの開発
- Principal Investigator
  
  秋山佳之
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Shinshu University
Elucidating structural diversity and functional significance of the MHC region using long-read sequencingPrincipal Investigator
- Principal Investigator
  
  曽根原究人
- Project Period (FY)
  2025 – 2026
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  The University of Tokyo
Genome-wide elucidation of disease susceptibility structural variation using short- and long-read sequencingPrincipal Investigator
- Principal Investigator
  
  曽根原究人
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  The University of Tokyo

All 2024 2023

All Journal Article Presentation

[Journal Article] Genetic drivers of heterogeneity in type 2 diabetes pathophysiology2024
- Author(s)
  Suzuki Ken、Hatzikotoulas Konstantinos、Southam Lorraine、Taylor Henry J.、Yin Xianyong、Lorenz Kim M.、Mandla Ravi、Huerta-Chagoya Alicia、Melloni Giorgio E. M.、Kanoni Stavroula、Rayner Nigel W.、Bocher Ozvan、Arruda Ana Luiza、Sonehara Kyuto et al.
- Journal Title
  
  Nature
  
  Volume: 627 Issue: 8003 Pages: 347-357
- DOI
  10.1038/s41586-024-07019-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K14451, KAKENHI-PROJECT-21H04850, KAKENHI-PROJECT-21H03206
[Journal Article] Genome-wide association study identifies risk loci within the major histocompatibility complex region for Hunner-type interstitial cystitis2023
- Author(s)
  Akiyama Y、Sonehara K、Maeda D、Katoh H、Naito T、Yamamoto K、Morisaki T、Ishikawa S、Ushiku T、Kume H、Homma Y、Okada Y
- Journal Title
  
  Cell Reports Medicine
  
  Volume: 4 Issue: 7 Pages: 101114-101114
- DOI
  10.1016/j.xcrm.2023.101114
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K16788, KAKENHI-PROJECT-23K14451, KAKENHI-PROJECT-22K07538, KAKENHI-PROJECT-22H00476
[Journal Article] Extracting immunological and clinical heterogeneity across autoimmune rheumatic diseases by cohort-wide immunophenotyping2023
- Author(s)
  Tanaka Hiroaki、Okada Yukinori、Nakayamada Shingo、Miyazaki Yusuke、Sonehara Kyuto et al.
- Journal Title
  
  Annals of the Rheumatic Diseases
  
  Volume: 83 Issue: 2 Pages: 242-252
- DOI
  10.1136/ard-2023-224537
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K14451, KAKENHI-PROJECT-22H00476, KAKENHI-PROJECT-23K24465
[Journal Article] Pan-cancer and cross-population genome-wide association studies dissect shared genetic backgrounds underlying carcinogenesis2023
- Author(s)
  Sato Go、Shirai Yuya、Namba Shinichi、Edahiro Ryuya、Sonehara Kyuto et al.
- Journal Title
  
  Nature Communications
  
  Volume: 14 Issue: 1 Pages: 3671-3671
- DOI
  10.1038/s41467-023-39136-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K14451, KAKENHI-PROJECT-22K07538, KAKENHI-PROJECT-23K08128, KAKENHI-PROJECT-22H00476
[Journal Article] Reconstruction of the personal information from human genome reads in gut metagenome sequencing data2023
- Author(s)
  Tomofuji Yoshihiko、Sonehara Kyuto et al.
- Journal Title
  
  Nature Microbiology
  
  Volume: 8 Issue: 6 Pages: 1079-1094
- DOI
  10.1038/s41564-023-01381-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K14451, KAKENHI-PROJECT-22H00476
[Journal Article] Estimating gene-level false discovery probability improves eQTL statistical fine-mapping precision2023
- Author(s)
  Wang Qingbo S、Edahiro Ryuya、Namkoong Ho、Hasegawa Takanori、Shirai Yuya、Sonehara Kyuto et al.
- Journal Title
  
  NAR Genomics and Bioinformatics
  
  Volume: 5 Issue: 4
- DOI
  10.1093/nargab/lqad090
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K14451
[Journal Article] Single-cell analyses and host genetics highlight the role of innate immune cells in COVID-19 severity2023
- Author(s)
  Japan COVID-19 Task Force
- Journal Title
  
  Nature Genetics
  
  Volume: 55 Issue: 5 Pages: 753-767
- DOI
  10.1038/s41588-023-01375-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K16624, KAKENHI-PROJECT-23K14451, KAKENHI-PROJECT-22K08283, KAKENHI-PROJECT-23K11300, KAKENHI-PROJECT-21K09068, KAKENHI-PROJECT-22K15493, KAKENHI-PROJECT-22H00476, KAKENHI-PROJECT-23K27671
[Journal Article] Analysis of gut microbiome, host genetics, and plasma metabolites reveals gut microbiome-host interactions in the Japanese population2023
- Author(s)
  Tomofuji Yoshihiko、Kishikawa Toshihiro、Sonehara Kyuto et al.
- Journal Title
  
  Cell Reports
  
  Volume: 42 Issue: 11 Pages: 113324-113324
- DOI
  10.1016/j.celrep.2023.113324
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K14451, KAKENHI-PROJECT-21K08344, KAKENHI-PROJECT-22H00476
[Presentation] Genome-wide association and HLA fine-mapping analysis of Hunner-type interstitial cystitis identify predisposing class II HLA variants.2023
- Author(s)
  Kyuto Sonehara, Yoshiyuki Akiyama, Daichi Maeda, Hiroto Katoh, Tatsuhiko Naito, Kenichi Yamamoto, Biobank Japan Project, Takayuki Morisaki, Shumpei Ishikawa, Tetsuo Ushiku, Haruki Kume, Yukio Homma, Yukinori Okada
- Organizer
  The 14th International Workshop on Advanced Genomics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K14451
[Presentation] 頭蓋内胚細胞腫瘍のゲノムワイド関連解析は遺伝的背景の解明を通じ、病因と疫学の理解に貢献する2023
- Author(s)
  曽根原究人, 木村由依, 中野嘉子, 小澤達也, 藤井隆司, 富山新太, 鈴木智成, 山口秀, 三輪点, 大江直行, 深井順也, 河村淳史, 市村幸一, 西川亮, 岡田随象, 寺島慶太
- Organizer
  第82回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-23K14451
[Presentation] Genome-wide association and HLA fine-mapping analysis of Hunner-type interstitial cystitis identify predisposing class II HLA variants.2023
- Author(s)
  Kyuto Sonehara, Yoshiyuki Akiyama, Daichi Maeda, Hiroto Katoh, Tatsuhiko Naito, Kenichi Yamamoto, Biobank Japan Project, Takayuki Morisaki, Shumpei Ishikawa, Tetsuo Ushiku, Haruki Kume, Yukio Homma, Yukinori Okada
- Organizer
  The American Society of Human Genetics Annual Meeting 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K14451
[Presentation] Genome-wide association and HLA fine-mapping analysis of Hunner-type interstitial cystitis identify risk HLA variants.2023
- Author(s)
  Kyuto Sonehara, Yoshiyuki Akiyama, Daichi Maeda, Hiroto Katoh, Tatsuhiko Naito, Kenichi Yamamoto, Biobank Japan Project, Takayuki Morisaki, Shumpei Ishikawa, Tetsuo Ushiku, Haruki Kume, Yukio Homma, Yukinori Okada
- Organizer
  Human Genetics Asia 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K14451

1. 秋山佳之 (20529135)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
2. 前田大地 (30585500)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 蔵野信 (60621745)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 新美文彩 (00376451)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 野里博和 (40435764)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Sonehara Kyuto 曽根原 究人

曽根原 究人 ソネハラ キュウト

Research Projects

Research Products

Co-Researchers

横断的オミクス解析と機械学習による間質性膀胱炎の治療標的とバイオマーカーの開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidating structural diversity and functional significance of the MHC region using long-read sequencingPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Genome-wide elucidation of disease susceptibility structural variation using short- and long-read sequencingPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Genetic drivers of heterogeneity in type 2 diabetes pathophysiology2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Genome-wide association study identifies risk loci within the major histocompatibility complex region for Hunner-type interstitial cystitis2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Extracting immunological and clinical heterogeneity across autoimmune rheumatic diseases by cohort-wide immunophenotyping2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Pan-cancer and cross-population genome-wide association studies dissect shared genetic backgrounds underlying carcinogenesis2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Reconstruction of the personal information from human genome reads in gut metagenome sequencing data2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Estimating gene-level false discovery probability improves eQTL statistical fine-mapping precision2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Single-cell analyses and host genetics highlight the role of innate immune cells in COVID-19 severity2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Analysis of gut microbiome, host genetics, and plasma metabolites reveals gut microbiome-host interactions in the Japanese population2023

Author(s)

Journal Title

DOI

Data Source

[Presentation] Genome-wide association and HLA fine-mapping analysis of Hunner-type interstitial cystitis identify predisposing class II HLA variants.2023

Author(s)

Organizer

Data Source

[Presentation] 頭蓋内胚細胞腫瘍のゲノムワイド関連解析は遺伝的背景の解明を通じ 、病因と疫学の理解に貢献する2023

Author(s)

Organizer

Data Source

[Presentation] Genome-wide association and HLA fine-mapping analysis of Hunner-type interstitial cystitis identify predisposing class II HLA variants.2023

Author(s)

Organizer

Data Source

[Presentation] Genome-wide association and HLA fine-mapping analysis of Hunner-type interstitial cystitis identify risk HLA variants.2023

Author(s)

Organizer

Data Source

Sonehara Kyuto 曽根原究人

曽根原究人ソネハラキュウト

[Presentation] 頭蓋内胚細胞腫瘍のゲノムワイド関連解析は遺伝的背景の解明を通じ、病因と疫学の理解に貢献する2023