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CHIKIRA Makoto  千喜良 誠

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千喜良 誠  チキラ マコト

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Researcher Number 70006328
Other IDs
Affiliation (based on the past Project Information) *help 2009 – 2011: Chuo University, 理工学部, 教授
2000 – 2003: 中央大学, 理工学部, 教授
1993 – 1998: 中央大学, 理工学部, 教授
1991: 中央大学, 理工学部, 教授
Review Section/Research Field
Principal Investigator
Inorganic chemistry / 機能・物性・材料 / Inorganic chemistry
Keywords
Principal Investigator
DNA / ESR / フェナントロリン / EPR / NMR / DNA切断反応 / DNAファイバーESR / デグリコペプロマイシン / DNA-fiber ESR / シッフ塩基錯体 … More / DNAファイバー / 2D-NMR / 二核錯体 / 水溶性ポルフィリン / ブレオマイシン / phenanthroline zinc complex / Schiff-base complex / peptide copper complex / hydrolysis / oxidative cleaving / polynuclear metal complex / SOD活性 / ヒスチジン / アメリカ / 国際情報交換 / テトラペプチド / 銅(II)錯体 / フェナントロリン亜鉛錯体 / ペプチド銅錯体 / 加水分解 / 酸化的切断 / 複核金属錯体 / tripeptide / Ni(III) complex / oligonucleotide / phenathroline Pt(II) complex / phenathroline copper(II) complex / DNA cleaving reaction / DNA fiber ESR / Ni(III)錯体 / ポリアミン銅(II)錯体 / ペプチド銅(II)錯体 / 金属錯体 / ペプチドNi(III)錯体 / フェナントロリン白金(II)錯体 / トリペプチド / ニッケル(III)錯体 / オリゴヌクレオチド / 白金(II)錯体 / フェナントロリン銅(II)錯体 / DNA-fiber / porphyrin / polyamine / acridine / deglycopepromycin / bleomycin / エチレンジアミン / ポリフィリン / 複合配位子 / トリアミン銅錯体 / ポルフィリン / ポリアミン銅錯体 / アクリジン / water-soluble porphyrin / Schiff-base / phenanthroline / peptide-containing metal complexes / DNA-base sequences / specific recognition / ペプチド複合錯体 / 大環状ポリアミン / フェナントロリン錯体 / ぺプチド複合錯体 / 塩基配列特異性 / シッフ塩基 / DNA-ファイバーESR / 含ペプチド金属錯体 / DNA塩基配列 / 特異的認識 / プロテインスプライシング反応 / カチオン性シッフ塩基錯体 / 複合化金属錯体 / 一塩基多形 / 抗癌活性 / DNAコンジュゲート / 多核錯体 / 複合金属錯体 / DNA-ファイバー / ニトロシル鉄(II)錯体 / 不安定原子価金属錯体 … More
Except Principal Investigator
分子動力学 / XAFS / 距離幾何学 / ペプチド錯体 / NOESY / 亜鉛 / サイトコア / ジンクフィンガー / NMR / 人工金属蛋白質 / MerR / Zinc Finger / DNA結合蛋白質 Less
  • Research Projects

    (8 results)
  • Research Products

    (36 results)
  • Co-Researchers

    (3 People)
  •  Synthesis and characterization of composite metal complexes aiming at regulations of genetic informationPrincipal Investigator

    • Principal Investigator
      CHIKIRA Makoto
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Inorganic chemistry
    • Research Institution
      Chuo University
  •  DNA base recognition and reaction with polynuclear metal complexesPrincipal Investigator

    • Principal Investigator
      CHIKIRA Makoto
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      機能・物性・材料
    • Research Institution
      CHUO UNIVERSITY
  •  Regulation of orientation and the dynamic behavior of metal complexes bound to DNAPrincipal Investigator

    • Principal Investigator
      CHIKIRA Makoto
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      機能・物性・材料
    • Research Institution
      Chuo University
  •  Novel Binding Structures and Reactions of Metal Complexes of Some Combired LigandsPrincipal Investigator

    • Principal Investigator
      CHIKIRA Makoto
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Inorganic chemistry
    • Research Institution
      CHUO UNIVERSITY
  •  不安定原子価金属錯体とDNAとの結合構造解析Principal Investigator

    • Principal Investigator
      千喜良 誠
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Inorganic chemistry
    • Research Institution
      Chuo University
  •  Design of peptide-containing chelate metal complexes for recognition of specific base sequences in DNAPrincipal Investigator

    • Principal Investigator
      CHIKIRA Makoto
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Inorganic chemistry
    • Research Institution
      Chuo University
  •  DNA結合蛋白質に関連したHg・Znペプチド錯体の合成・NOESY・XAFS

    • Principal Investigator
      山村 剛士
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tokyo University of Science
  •  DNA結合蛋白質に関連したHg・Znペプチド錯体の合成・NOESY・XAFS

    • Principal Investigator
      山村 剛士
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tokyo University of Science

All 2012 2011 2010 2009 2004

All Journal Article Presentation

  • [Journal Article] DNA molecular recognition and cellular selectivity of anticancer metal (II) complexes of ethylenediaminediacetate and phenanthroline : multiple targets2012

    • Author(s)
      Sze-Tin Von, Hoi-Ling Seng, Hong-Boon Lee, Seik-Weng Ng, Yusuke Kitamura, Makoto Chikira, Chew-Hee Ng
    • Journal Title

      J.Inorg.Biol.Chem.

      Volume: 17 Issue: 1 Pages: 57-69

    • DOI

      10.1007/s00775-011-0829-0

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21550070
  • [Journal Article] DNA molecular recognition and cellular selectivity of anticancer metal(II) complexes of ethylenediaminediacetate and phenanthroline : multiple targets2012

    • Author(s)
      Sze-Tin Von、Hoi-Ling Seng、Hong-Boon Lee、Seik-Weng Ng、Yusuke Kitamura、Makoto Chikira、Chew-Hee Ng
    • Journal Title

      J. Inorg. Biol. Chem.

      Volume: Vol.17 No.1 Pages: 57-69

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21550070
  • [Journal Article] Conformational change of ternary copper (II) complexes of cationlc Schiff-bases and N-heteroaromatic amines induced by intercalative binding to DNA2011

    • Author(s)
      Yusuke Iwasaki, Masato Kimura, Atsushi Yamada, Yuichiro Mutoh, Maiko Tateishi, Hidekazu Arii, Yusuke Kitamura, Makoto Chikira
    • Journal Title

      Inorganic Chemistry Communications

      Volume: 14 Issue: 9 Pages: 1461-1464

    • DOI

      10.1016/j.inoche.2011.05.047

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21550070, KAKENHI-PUBLICLY-23105543, KAKENHI-PROJECT-23550082
  • [Journal Article] Conformational change of ternary copper(II) complexes of cationic Schiff-bases and N-heteroaromatic amines induced by intercalative binding to DNA Inorg2011

    • Author(s)
      Yusuke Iwasaki、Masato Kimura、Atsushi Yamada、Yuichiro Mutoh、Maiko Tateishi、Hidekazu Arii、Yusuke Kitamura、Makoto Chikira
    • Journal Title

      Chem. Commun.

      Volume: Vol.14 Pages: 1461-1464

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21550070
  • [Journal Article] Copper(II) complexes of methylated glycine derivatives : Effect of methyl substituent on their DNA binding and nucleolytic property2009

    • Author(s)
      Hoi Ling Seng、Kong Wai Tan、Mohd Jamil Maah、Wee Tee Tan、Hirokazu Hamada、Makoto Chikira、Chew Hee Ng
    • Journal Title

      Polyhedron

      Volume: Vol.28, No.11 Pages: 2219-2227

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21550070
  • [Journal Article] Effect of a conjugated acridine moiety on the binding and reactivity of Cu(II)[9-acridinylmethyl-1,4,7-triazacyclononane] with DNA2004

    • Author(s)
      Tomoya Hirohama, Hidekazu Arii, Makoto Chikira
    • Journal Title

      J.Inorg.Biochem. vol.98

      Pages: 1778-1786

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14540541
  • [Journal Article] EPR study of the dynamic behavior of cis,cis-1,3,5-triaminocyclohexane Cu(II) complex on B-form DNA-fibers2004

    • Author(s)
      Tomoya Hirohama, Akiko Chiba, Makoto Chikira
    • Journal Title

      J.Inorg.Biochem. vol.98

      Pages: 371-376

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14540541
  • [Presentation] Synthesis of the DNA conjugates with metal chelator through cysteine moiety and the application to SNPs analysis2011

    • Author(s)
      Yuji Sakurai、Atsushi Nakano、Ayami Nogami、Toshihiro Ihara、Yusuke Kitamura、Makoto Chikira
    • Organizer
      3rd Asian Conference on Coordination Chemistry
    • Place of Presentation
      New Delhi、India
    • Year and Date
      2011-10-19
    • Data Source
      KAKENHI-PROJECT-21550070
  • [Presentation] N-メチルピリジニウムシッフ塩基銅(II)錯体の合成とDNAとの相互作用の評価2011

    • Author(s)
      高北翔大・三好正宣・朝日向晃良・北村裕介・千喜良誠
    • Organizer
      第61回錯体化学討論会
    • Place of Presentation
      岡山理科大学
    • Year and Date
      2011-09-17
    • Data Source
      KAKENHI-PROJECT-21550070
  • [Presentation] 新規カチオン性シッフ塩基銅(II)二核錯体のDNA結合親和性及び切断活性の評価2011

    • Author(s)
      原佳恵, 朝日向晃良, 北村裕介, 千喜良誠
    • Organizer
      第61回錯体化学討論会
    • Place of Presentation
      岡山理科大学
    • Year and Date
      2011-09-18
    • Data Source
      KAKENHI-PROJECT-21550070
  • [Presentation] 鋳型特異的にルテニウム-白金二核錯体を脱離する新規DNAブロープの設計とその遺伝子解析への応用2011

    • Author(s)
      戸田健太郎、富森岳、三田聡司、北村裕介、千喜良誠
    • Organizer
      日本分析化学会第60年会
    • Place of Presentation
      名古屋大学・東山ホール
    • Year and Date
      2011-09-15
    • Data Source
      KAKENHI-PROJECT-21550070
  • [Presentation] Effect of asymmetric bridging group on the binding of cationic salen type Schiff base complexes of nickel(II) to DNA2011

    • Author(s)
      Yoko Taruno、Yusuke Kitamura、Makoto Chikira
    • Organizer
      3rd Asian Conference on Coordination Chemistry
    • Place of Presentation
      New Delhi、India
    • Year and Date
      2011-10-19
    • Data Source
      KAKENHI-PROJECT-21550070
  • [Presentation] DNA cleavage activity of dipicolylamine copper (II) complex tethered to Schiff base copper (II) complex2011

    • Author(s)
      Akiyosi Asahina, Yusuke Kitamura, Makoto Chikira
    • Organizer
      3rd Asian Conference on Coordination Chemistry
    • Place of Presentation
      India Habitat Centre, New Delhi, India
    • Year and Date
      2011-10-17
    • Data Source
      KAKENHI-PROJECT-21550070
  • [Presentation] リンカー部位にシステインを有する金属配位性DNAコンジュゲートの合成とその一塩基多型解析への応用2011

    • Author(s)
      櫻井悠司、中野篤、野上礼美、井原敏博、北村裕介、千喜良誠
    • Organizer
      日本分析化学会第60年会
    • Place of Presentation
      名古屋大学・東山ホール
    • Year and Date
      2011-09-15
    • Data Source
      KAKENHI-PROJECT-21550070
  • [Presentation] DNA binding affinity and cleavage activity of dicopper(II) Schiff base complex with cationic substituents2011

    • Author(s)
      Yoshie Hara、Akiyoshi Asahina、Yusuke Kitamura、Makoto Chikira
    • Organizer
      3rd Asian Conference on Coordination Chemistry
    • Place of Presentation
      New Delhi、India
    • Year and Date
      2011-10-19
    • Data Source
      KAKENHI-PROJECT-21550070
  • [Presentation] Effect of cationic side chains on the DNA binding and cleavage activity of Schiff base Copper (II) complexes having heterocyclic ligands2011

    • Author(s)
      Masato Kimura, Yusuke Iwasaki, Yusuke Kitamura, Makoto Chikira
    • Organizer
      3rd Asian Conference on Coordination Chemistry
    • Place of Presentation
      India Habitat Centre, New Delhi, India
    • Year and Date
      2011-10-17
    • Data Source
      KAKENHI-PROJECT-21550070
  • [Presentation] DNA cleavage activity of dipicolylamine copper(II) complex tethered to Schiff base copper(II) complex2011

    • Author(s)
      Akiyosi Asahina、Yusuke Kitamura、Makoto Chikira
    • Organizer
      3rd Asian Conference on Coordination Chemistry
    • Place of Presentation
      New Delhi、India
    • Year and Date
      2011-10-19
    • Data Source
      KAKENHI-PROJECT-21550070
  • [Presentation] Synthesis of N-methylpyridinium Schiff base copper(II) complexes and evaluation of the interaction with DNA2011

    • Author(s)
      Shota Takakita、Masanobu Miyoshi、Akiyoshi Asahina、Yusuke Kitamura、Makoto Chikira
    • Organizer
      3rd Asian Conference on Coordination Chemistry
    • Place of Presentation
      New Delhi、India
    • Year and Date
      2011-10-19
    • Data Source
      KAKENHI-PROJECT-21550070
  • [Presentation] Synthesis of the DNA conjugates with metal chelator through cysteine moiety and the application to SNPs analysis2011

    • Author(s)
      Yuji Sakurai, Atsushi Nakano, Ayami Nogami, Toshihiro Ihara, Yusuke Kitamura, Makoto Chikira
    • Organizer
      3rd Asian Conference on Coordination Chemistry
    • Place of Presentation
      India Habitat Centre, New Delhi, India
    • Year and Date
      2011-10-17
    • Data Source
      KAKENHI-PROJECT-21550070
  • [Presentation] Effect of asymmetric bridging group on the binding of cationic salen type Schiff base complexes of nickel (II) to DNA2011

    • Author(s)
      Yoko Taruno, Yusuke Kitamura, Makoto Chikira
    • Organizer
      3rd Asian Conference on Coordination Chemistry
    • Place of Presentation
      India Habitat Centre, New Delhi, India
    • Year and Date
      2011-10-17
    • Data Source
      KAKENHI-PROJECT-21550070
  • [Presentation] DNA binding affinity and cleavage activity of dicopper (II) Schiff base complex with cationic substituents2011

    • Author(s)
      Yoshie Hara, Akiyoshi Asahina, Yusuke Kitamura, Makoto Chikira
    • Organizer
      3rd Asian Conference on Coordination Chemistry
    • Place of Presentation
      India Habitat Centre, New Delhi, India
    • Year and Date
      2011-10-19
    • Data Source
      KAKENHI-PROJECT-21550070
  • [Presentation] Effect of cationic side chains on the DNA binding and cleavage activity of Schiff base Copper(II) complexes having heterocyclic ligands2011

    • Author(s)
      Masato Kimura、Yusuke Iwasaki、Yusuke Kitamura、Makoto Chikira
    • Organizer
      3rd Asian Conference on Coordination Chemistry
    • Place of Presentation
      New Delhi、India
    • Year and Date
      2011-10-19
    • Data Source
      KAKENHI-PROJECT-21550070
  • [Presentation] Interaction of Salicylidene Amino Acid Schiff-base Oxovanadium(IV) Complexes with DNA2011

    • Author(s)
      Kazuya Takahashi、Asami Sano、Yusuke Kitamura、Makoto Chikira
    • Organizer
      3rd Asian Conference on Coordination Chemistry
    • Place of Presentation
      New Delhi、India
    • Year and Date
      2011-10-19
    • Data Source
      KAKENHI-PROJECT-21550070
  • [Presentation] Synthesis of N-methylpyridinium Schiff base copper (II) complexes an evaluation of the interaction with DNA2011

    • Author(s)
      Shota Takakita, Masanobu Miyoshi, Akiyoshi Asahina, Yusuke Kitamura, Makoto Chikira
    • Organizer
      3rd Asian Conference on Coordination Chemistry
    • Place of Presentation
      India Habitat Centre, New Delhi, India
    • Year and Date
      2011-10-17
    • Data Source
      KAKENHI-PROJECT-21550070
  • [Presentation] 架橋部位に不斉を有するカチオン性サレン型シッフ塩基ニッケル(II)錯体とDNAとの結合構造解析2011

    • Author(s)
      埀野陽子・北村裕介・千喜良誠
    • Organizer
      第61回錯体化学討論会
    • Place of Presentation
      岡山理科大学
    • Year and Date
      2011-09-17
    • Data Source
      KAKENHI-PROJECT-21550070
  • [Presentation] ジピコリルアミン銅(II)錯体を連結したシッフ塩基銅(II)三核錯体の合成とDNA切断活性の評価2011

    • Author(s)
      朝日向晃良・北村裕介・千喜良誠
    • Organizer
      第61回錯体化学討論会
    • Place of Presentation
      岡山理科大学
    • Year and Date
      2011-09-17
    • Data Source
      KAKENHI-PROJECT-21550070
  • [Presentation] DNA binding structure of zinc(II) and platinum(II) complexes with aromatic amine and edda2010

    • Author(s)
      Yusuke Nakamura、Hoi-Ling Seng、Chew-Hee Ng、Makoto Chikira
    • Organizer
      2010 International Chemical Congress of Pacific Basin Societies
    • Place of Presentation
      Honolulu、Hawaii
    • Year and Date
      2010-12-16
    • Data Source
      KAKENHI-PROJECT-21550070
  • [Presentation] Development of noble gene probes based on DNA-templated formation of platinum-ruthenium dinuclear complex2010

    • Author(s)
      Yusuke Kitamura、Takeshi Tomimori、Satoshi Mita、Makoto Chikira
    • Organizer
      2010 International Chemical Congress of Pacific Basin Societies
    • Place of Presentation
      Honolulu、Hawaii
    • Year and Date
      2010-12-17
    • Data Source
      KAKENHI-PROJECT-21550070
  • [Presentation] Comparative study of the interactions of Schiffbase-N-heteroaromatic amine ternary complexes of Cr(III) and Cu(II) with DNA2010

    • Author(s)
      Shota Kitajima、Masato Kimura、Yusuke Kitamura、Makoto Chikira
    • Organizer
      2010 International Chemical Congress of Pacific Basin Societies
    • Place of Presentation
      Honolulu、Hawaii
    • Year and Date
      2010-12-16
    • Data Source
      KAKENHI-PROJECT-21550070
  • [Presentation] Template-directed formation of luminescent lanthanide complex using the DNA probes and application to gene analysis2010

    • Author(s)
      Nobuhiko Kaihara、Yusuke Kitamura、Takeshi Tomimori、Toshihiro Ihara、Makoto Chikira
    • Organizer
      2010 International Chemical Congress of Pacific Basin Societies
    • Place of Presentation
      Honolulu、Hawaii
    • Year and Date
      2010-12-17
    • Data Source
      KAKENHI-PROJECT-21550070
  • [Presentation] Effect of cationic side chains on the interaction between DNA and amino acid Schiff base copper(II) complexes having heterocyclic ligands2010

    • Author(s)
      Masato Kimura、Yusuke Iwasaki、Yusuke Kitamura、Makoto Chikira
    • Organizer
      60th Anniversary Conference on Coordination Chemistry in OSAKA、JAPAN
    • Place of Presentation
      Osaka、Japan
    • Year and Date
      2010-09-27
    • Data Source
      KAKENHI-PROJECT-21550070
  • [Presentation] Interaction of salicylideneamino acid Schiff base oxovanadium(IV) complexes with DNA2010

    • Author(s)
      Kazuya Takahashi、Asami Sano、Yusuke Kitamura、Makoto Chikira
    • Organizer
      60th Anniversary Conference on Coordination Chemistry in OSAKA、Japan
    • Place of Presentation
      Osaka、Japan
    • Year and Date
      2010-09-27
    • Data Source
      KAKENHI-PROJECT-21550070
  • [Presentation] The synthesis、chHaracterization and DNA modification of new dicopper Schiff-base complexes2010

    • Author(s)
      Jian Shi、Midori Tojo、Yusuke Kitamura、Makoto Chikira
    • Organizer
      2010 International Chemical Congress of Pacific Basin Societies
    • Place of Presentation
      Honolulu、Hawaii
    • Year and Date
      2010-12-16
    • Data Source
      KAKENHI-PROJECT-21550070
  • [Presentation] Interaction of Heterodinuclear Cationic Schiff Base Metal Complex with DNA2009

    • Author(s)
      Makoto Chikira
    • Organizer
      14^<th> International Conference on Biological Inorganic Chemistry
    • Place of Presentation
      Nagoya Congress Center,(Nagoya, Japan)
    • Year and Date
      2009-07-26
    • Data Source
      KAKENHI-PROJECT-21550070
  • [Presentation] Interaction of Dinuclear Cationic Schiff Base Metal Complexes with DNA2009

    • Author(s)
      Makoto Chikira
    • Organizer
      The Fourth Symposium on Advanced in Biological Inorganic Chemistry
    • Place of Presentation
      TIFR(Mumbai, India)
    • Year and Date
      2009-11-05
    • Data Source
      KAKENHI-PROJECT-21550070
  • [Presentation] Nucleolytic Properties of Dinuclear Cationic Schiff Base Cu(II)and Ni(II)Complexes2009

    • Author(s)
      Makoto Chikira
    • Organizer
      16th International SPACC Symposium
    • Place of Presentation
      Liaocheng Univ.(China)
    • Year and Date
      2009-10-29
    • Data Source
      KAKENHI-PROJECT-21550070
  • 1.  山村 剛士 (00114702)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 2.  KITAMURA Yusuke (80433019)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 29 results
  • 3.  ISHIZUKA Morio (50168241)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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