FUKUI Kazuhiro 福井一博

Researcher Number	70034171
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2004 – 2007: OKAYAMA UNIVERSITY, Graduate School of Medicine and Dentistry, Professor, 大学院・医歯薬学総合研究科, 教授 2005 – 2006: 岡山大学, 大学院医歯薬学総合研究科, 教授 2001 – 2004: 岡山大学, 大学院・医歯学総合研究科, 教授 2003: 岡山大学, 大学院・医歯学研究科, 教授 1992 – 2000: 岡山大学, 歯学部, 教授 1986 – 1991: 岡山大学, 歯学部, 助教授
Review Section/Research Field	Principal Investigator Morphological basic dentistry / Pathobiological dentistry/Dental radiology / Functional basic dentistry / Conservative dentistry Except Principal Investigator Morphological basic dentistry / Morphological basic dentistry / Pathobiological dentistry/Dental radiology / Functional basic dentistry
Keywords	Principal Investigator GTF-I / Streptococcus sobrinus / 不溶性グルカン合成酵素 / Streptococcus / PCR / glucosyltransferase / catalytic domain / oral streptococci / 触媒ドメイン / デキストラン … More / 口腔連鎖球菌 / 16SrDNA / 口腔細菌 / Helicobacter pylori / water-insoluble glucan / GTF / グルカン合成酵素 / Streptococcus mutans / ミュータンスレンサ球菌 / dextran binding domain / cloning / glucosyltransferase gene / スクラーゼ / 蔗糖 / グルコシールトランスフェレース遺伝子のクローニング / スクラ-ゼ / ショ糖 / クロ-ニング / グルコシ-ルトランスフェレ-ス / 不溶性グネカン合成酵素 / クローニング / デキストラン結合能 / グルコシルトランスフェレース / 水溶性グルカン合成酵素遺伝子 / Infectious Disease / Biofilm / Metagenome / Bacteria / ゲノム / 感染症 / バイオフィルム / メタゲノム / 細菌 / dextran-binding domain / domain interaction / insoluble glucan synthetase / エンタルピー / 等温滴定熱測定 / デキストラン結合ドメイン / ドメイン間相互作用 / crystallization / secondary structure / dextran / insoluble glucan synthease / 立体構造 / 大量発現系 / X線結晶解析 / 立体構造解析 / 口腔レンサ球菌 / 結晶化 / 二次構造 / 水不溶性グルカン合成酵素 / periodontal bacteria / dental caries / bacterial community / 16S rRNA / genotype / 齲蝕 / 歯周病原細菌 / う蝕 / 細菌叢 / chemostat culture / morphologic conversion / duodenal ulcer / gastric ulcer / 生態学 / ケモスタット / 球状体 / 胃潰瘍・十二指腸潰瘍 / ヘリコバクター・ピロリ / dextran-dependent / alpha-1,3 glucan / function asd structure / グルカン合成酵素遺伝子 / streptococcus mutans / GTF遺伝子 / 不溶性グルカン / Glucosyltransferase / water-soluble glucan synthesis / cloning GTF gene / Streptococcous cricetus / GTF-S gene / α-1,6 glucan synthase / glucosyltransferase-S / dextransucrase / mutans streptococci / う蝕原性細菌 / 遺伝子クローニング / 水溶性グルカン合成酵素 / 診断法開発 / 口腔病態検査 / 口腔内細菌叢 / 口腔内気体成分 … More Except Principal Investigator Actinobacillus actinomycetemcomitans / 歯周病 / A.actinomycetemcomitans / 白血球毒素 / 歯周病細菌 / Actinobacillus / Porphyromonas gingivalis / Leukotoxin / Streptococcus mutans / バイオフィルム / amphipathic substance / liooteichoic acid / Streprococcus pyogenes / TNF誘導活性 / TNF / Streptococcus pyogens / 両親媒性物質・腫瘍壊死因子の誘導 / リポタイコ酸 / 化膿レンサ球菌 / periodontal disease / leukotoxin / cell-cell aggregation / adherence / exopolysaccharide / fimbriae / biofilm / 菌体表層多糖 / 初期付着 / ミクロコロニー / 自己凝集 / 付着 / 菌体外多糖 / 線毛 / development for new anitibiotics / bacterial iron binding protein / X-ray crystal structure analysis / X線結晶構造解析 / 蛋白質結晶化 / リコンビナント蛋白 / 病原細菌 / フェリチン / Dps / Streptococcus pneumoniae / Staphylococcus aureus / Actihobacillus actinomycetemcomitans / 細菌鉄結合蛋白 / Actinobacillus actinornycetemcomitans / 細菌 / 新規抗菌薬探求 / 鉄結合蛋白 / X線結晶解析 / bacterial genes / in vivo-expressing / periodontopathic bacteria / 遺伝子解析 / Actimobacillus actinomycetemcomitans / 細菌遺伝子 / 生体内発現 / Periodontal disease / A. actinomycetemcomitans / Periodontitis / A.actinomycetem-comitans / A・actinomycetemcomitans / H^+-ATPase / energy metabolism / ATP utilization / ATP generation / エネルギ-代謝 / エネルギー代謝 / ATP / Streptococcus Mutans / Mip様遺伝子 / サブトラクティブハイブリダイゼーション法 / プロテオミクス / ゲノム / 発現様態 / 病原因子 Less

口腔内気体成分組成と口腔内細菌叢の統合的解析に基づく口腔病態検査・診断法の開発Principal Investigator
- Principal Investigator
  
  福井一博
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Okayama University
New Approach to the Study on Oral Biofilm Infectious Diseases by Metagenomic AnalysisPrincipal Investigator
- Principal Investigator
  
  FUKUI Kazuhiro
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Okayama University
バイオフィルムにおける歯周病細菌病原因子発現様態のゲノム-プロテオミクス解析
- Principal Investigator
  
  KOKEGUCHI Susumu
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Okayama University
X-ray Crystal Structural Analysis of Bacterial Iron Binding Protein and Development for New Antibiotics
- Principal Investigator
  
  KOKEGUCHI Susumu
- Project Period (FY)
  2003 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  OKYAMA UNIVERSITY
Regulation of gene expression of periodontal virulence factors during biofilm formation
- Principal Investigator
  
  INOUE Tetsuyoshi
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  OKAYAMA UNIVERSITY
Three-dimensional structural analysis and development of new inhibitors of glucan synthetase produced by cariogenic oral streptococciPrincipal Investigator
- Principal Investigator
  
  FUKUI Kazuhiro
- Project Period (FY)
  2001 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Conservative dentistry
- Research Institution
  OKAYAMA UNIVERSITY
Investigation and characterization for the periodontopathic bacterial genes specifically expressing in vivo
- Principal Investigator
  
  KOKEGUCHI Susumu
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Okayama University
Analysis of domain interaction in insoluble glucan synthetase of oral streptococciPrincipal Investigator
- Principal Investigator
  
  FUKUI Kazuhiro
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Okayama University
Molecular biological analysis of oral bacterial population dynamicsPrincipal Investigator
- Principal Investigator
  
  FUKUI Kazuhiro
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Okayama University
Ecological analysis of Helicobacter pylori in oral cavitiesPrincipal Investigator
- Principal Investigator
  
  FUKUI Kazuhiro
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Okayama University
Function and structure of glucosyltransferase of Streptococcus sobrinusPrincipal Investigator
- Principal Investigator
  
  FUKUI Kazuhiro
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Okayama University
Regulation of leukotoxin synthesis in Actinobacillus actinomycetemcomitans
- Principal Investigator
  
  OHTA Hiroyuki
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  OKAYAMA UNIVERSITY DENTAL SCHOOL
Effects of environment conditions on the production of leukotoxin by Actinobacillus actinomycetemcomitans
- Principal Investigator
  
  OHTA Hiroyuki
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Okayama University Dental School
Function and structure of Streptococus sobrinus glucosyltransferase responsible for water-soluble glucan synthesisPrincipal Investigator
- Principal Investigator
  
  FUKUI Kazuhiro
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Okayama University
ATP metabolism in Streptococcus mutans
- Principal Investigator
  
  KODAMA Takao
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  OKAYAMA UNIVERSITY
Cloning of the gene encoding glucosyltransferase from Streptococcus sobrinusPrincipal Investigator
- Principal Investigator
  
  FUKUI Kazuhiro
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Okayama University
Production, cheracterization and purification of liporeichoic acide capable of inducting tumor recrosis factor (TNF)
- Principal Investigator
  
  KATO Keijito
- Project Period (FY)
  1986 – 1987
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Okayama Univwersity

All 2008 2007 2006 2005

All Journal Article

[Journal Article] Rapid and simple detection of major eight periodontal pathogens by loop-mediated isothermal amplification method2008
- Author(s)
  Miyagawa, J., Maeda, H., Murauchi, T., Kokeguchi, S., Tanimoto, I., Nishimura, F., Fukui, K., Takashiba, S
- Journal Title
  
  FEMS Immunology and Medical Microbiology (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390502
[Journal Article] 歯学部学生のメチシリン耐性ブドウ球菌の保菌調査と院内感染に関する意識調査について2007
- Author(s)
  渡辺朱理, 佐藤法仁, 苔口進, 福井一博
- Journal Title
  
  日本歯科衛生学会雑誌 1巻・2号
  
  Pages: 25-33
- NAID
  40015392692
- Data Source
  KAKENHI-PROJECT-17390502
[Journal Article] Genome-wide screening of genes required for swarming motility in Escherichia coli K-122007
- Author(s)
  Inoue T, Shingaki R, Hirose S, Waki K, Mori H, Fukui K
- Journal Title
  
  J.Bacteriol. 189巻・3号
  
  Pages: 950-7
- Data Source
  KAKENHI-PROJECT-17390502
[Journal Article] Leukotoxin production by Actinobacillus actinomycetemcomitans2006
- Author(s)
  Inoue T, Fukui K, Ohta H
- Journal Title
  
  Toxin Reviews 25巻・1号
  
  Pages: 1-18
- Data Source
  KAKENHI-PROJECT-17659591
[Journal Article] Composition of the bacterial flora tonsilloliths2006
- Author(s)
  Tsuneishi M, Yamamoto T, Kokeguchi S, Tamaki N, Fukui K, Watanabe T
- Journal Title
  
  Microbes Infect. 8巻・9-10号
  
  Pages: 2384-9
- Data Source
  KAKENHI-PROJECT-17390502
[Journal Article] Composition of the bacterial flora in tonsilloliths2006
- Author(s)
  Tsuneishi M, Yamamoto T, Kokeguchi S, Tamaki N, Fukui K, Watanabe T.
- Journal Title
  
  Microbes Infect. 8巻・9-10号
  
  Pages: 2384-9
- Data Source
  KAKENHI-PROJECT-15390566
[Journal Article] Leukotoxin production by Actinobacillus actionmycetemcomitans2006
- Author(s)
  Inoue T, Fukui K, Ohta H
- Journal Title
  
  Toxin Reviews 25巻・1号
  
  Pages: 1-18
- Data Source
  KAKENHI-PROJECT-17390502
[Journal Article] Composition of the bacterial flora in tonsilloliths2006
- Author(s)
  Tsuneishi, M., Yamamoto, T., Kokeguchi, S., Tamaki, N., Fukui, K., Watanabe, T
- Journal Title
  
  Microbes Infect 8(9-10)
  
  Pages: 2384-2389
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390502
[Journal Article] Composition of the bacterial flora in tonsilloliths2006
- Author(s)
  Tsuneishi M, Yamamoto T, Kokeguchi S, Tamaki N, Fukui K, Watanabe T
- Journal Title
  
  Microbes Infect. 8巻・9-10号
  
  Pages: 2384-2389
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390566
[Journal Article] 難培微生物群集へのメタゲノム解析によるアプローチ2006
- Author(s)
  苔口進, 前田博史, 玉木直文, 福井一博
- Journal Title
  
  日本細菌学雑誌 60巻・3号
  
  Pages: 491-494
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390566
[Journal Article] Composition of the bacterial flora in tonsilloliths.2006
- Author(s)
  Tsuneishi M, Yamamoto T, Kokeguchi S, Tamaki N, Fukui K, Watanabe T.
- Journal Title
  
  Microbes Infect. 8(9-10)
  
  Pages: 2384-2389
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390566
[Journal Article] Composition of the bacterial flora in tonsilloliths2006
- Author(s)
  Tsuneishi M, Yamamoto T, Kokeguchi S, Tamaki N, Fukui K, Watanabe T
- Journal Title
  
  Microbes Infect. 8巻・9-10号
  
  Pages: 2384-2389
- Data Source
  KAKENHI-PROJECT-17659591
[Journal Article] 難培微生物群集へのメタゲノム解析によるアプローチ2005
- Author(s)
  苔口進, 前田博史, 玉木直文, 福井一博
- Journal Title
  
  日本細菌学雑誌 60巻・3号
  
  Pages: 491-494
- Data Source
  KAKENHI-PROJECT-17390502
[Journal Article] 難培養微生物群集へのメタゲノム解析によるアプローチ2005
- Author(s)
  苔口進, 前田博史, 玉木直文, 福井一博
- Journal Title
  
  日本細菌学雑誌 60(3)
  
  Pages: 491-494
- NAID
  130001386150
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390502
[Journal Article] New approach to uncultivable microbial communities by metagenomic analysis2005
- Author(s)
  Kokeguchi, S., Maeda, H., Tamaki, N., Fukui, K
- Journal Title
  
  Nippon Saikingaku Zasshi 60(3)
  
  Pages: 491-494
- NAID
  130001386150
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390502
[Journal Article] 難培微生物群集へのメタゲノム解析によるアプローチ2005
- Author(s)
  苔口進, 前田博史, 玉木直文, 福井一博
- Journal Title
  
  日本細菌学雑誌 60巻・3号
  
  Pages: 491-494
- Data Source
  KAKENHI-PROJECT-16659499
[Journal Article] New approach to uncultivable microbial communities by metagenomic analysis.2005
- Author(s)
  Kokeguchi S, Maeda H, Tamaki N, Fukui K.
- Journal Title
  
  Nippon Saikingaku Zasshi. 60(3)
  
  Pages: 491-494
- NAID
  130001386150
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390566
[Journal Article] 初診時感染源除去法における歯周ポケット内細菌叢の変化2005
- Author(s)
  玉木直文, 苔口進, 恒石美登里, 山本龍生, 福井一博, 渡邊達夫
- Journal Title
  
  歯界展望 105(1)
  
  Pages: 269-269
- Data Source
  KAKENHI-PROJECT-17659591

1. KOKEGUCHI Susumu (10144776)

# of Collaborated Projects: 11 results

# of Collaborated Products: 15 results
2. INOUE Tetsuyoshi (20223258)

# of Collaborated Projects: 8 results

# of Collaborated Products: 0 results
3. OHTA Hiroyuki (80168947)

# of Collaborated Projects: 8 results

# of Collaborated Products: 0 results
4. MAEDA Hiroshi (00274001)

# of Collaborated Projects: 5 results

# of Collaborated Products: 7 results
5. SHINGAKI Ryuuji (40294417)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
6. TAKASHIBA Shogo (50226768)

# of Collaborated Projects: 4 results

# of Collaborated Products: 1 results
7. KODAMA Takao (30034200)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
8. OZAKI Miho (20271059)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
9. NISHIMURA Fusanori (80208222)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
10. TANIMOTO Ichiro (00280686)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
11. MIYAGI Atsushi (40243464)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. KATO Keijito (50028718)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. KARIYAMA Reiko (40112148)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
14. 玉木直文 (20335615)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
15. ARAI Hideo (70222718)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 山本龍生 (20252984)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
17. 恒石美登里 (50304324)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
18. 片岡洋行 (80127555)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 嶋本達家 (30170963)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 小西法文 (60243466)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 村山洋二 (50029972)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. YAMAMOTO Akihiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

FUKUI Kazuhiro 福井 一博

Research Projects

Research Products

Co-Researchers

口腔内気体成分組成と口腔内細菌叢の統合的解析に基づく口腔病態検査・診断法の開発Principal Investigator

Principal Investigator

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New Approach to the Study on Oral Biofilm Infectious Diseases by Metagenomic AnalysisPrincipal Investigator

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Three-dimensional structural analysis and development of new inhibitors of glucan synthetase produced by cariogenic oral streptococciPrincipal Investigator

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Analysis of domain interaction in insoluble glucan synthetase of oral streptococciPrincipal Investigator

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Molecular biological analysis of oral bacterial population dynamicsPrincipal Investigator

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Ecological analysis of Helicobacter pylori in oral cavitiesPrincipal Investigator

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Function and structure of glucosyltransferase of Streptococcus sobrinusPrincipal Investigator

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Function and structure of Streptococus sobrinus glucosyltransferase responsible for water-soluble glucan synthesisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

FUKUI Kazuhiro 福井一博