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OH-ISHI Sachiko  大石 幸子

ORCIDConnect your ORCID iD *help
Researcher Number 70050416
Affiliation (based on the past Project Information) *help 1992 – 1999: 北里大学, 薬学部, 教授
1986 – 1989: 北里大学, 薬学部, 教授
1987: 北里大学, 薬学部・薬理学教室, 教授
Review Section/Research Field
Principal Investigator
Biological pharmacy / 応用薬理学・医療系薬学
Except Principal Investigator
物質生物化学 / Biological pharmacy
Keywords
Principal Investigator
PGE2 / エンドトキシン / カラゲニン胸膜炎 / カリクレイン・キニン系 / ブラジキニン / 低分子キニノゲン / 高分子キニノゲン / キニノゲン欠損ラット / Radioimmunoassay / Eicosanoids … More / Kininogen-deficient rat / Rat pleurisy / Inflammation / T-kininogen / LMW-kininogen / HMW-kininogen / カラゲニン足浮腫 / カプトプリル / 性差 / 急性相蛋白質 / Tーキニノゲン / ラジオイムノアッセイ / アラキドン酸代謝物 / 炎症反応 / T-キニノゲン / Macrophages / Inducible enzyme / PDE synthase / Cyclooxygenase / Prostaglandins / Arachidonate Metabolites / リポポリサッカライド / トロンボキサンB_2 / プロスタグランジンD_2 / プロスタグランジンE_2 / シクロオキシゲナーゼ-2 / シクロオキシゲナーゼ-1 / ホスホリパーゼA_2 / PGI_2 / マクロファージ / PGI2 / PGE合成酵素 / COX-2 / アラキドン酸 / BRADYKININ / LLOW MOLECULAR WEIGHT KININOGEN / HIGH MOLECULAR WEIGHT KININOGEN / SECRETION DEFECT / A POINT MUTATION / KININOGEN-DEFICIENT RAT / KININOGEN / 血管透過性亢進 / ブラジキニン・アンタゴニスト / 高血圧 / Brown Norway rat / ワンポイントミューテーション / ブラウン・ノルウェイ・ラット / N・KatholieK rat / B / 尿キニン / 一アミノ酸変異 / 分泌異常 / 点変異 / キニノゲン … More
Except Principal Investigator
PAF / kinin release / initiation reaction / Blood coagulation / 接触反応 / 線溶系 / キニン / 開始反応 / 血液凝固 / prostaglandin / cyclooxygenase / phospholipase A_2 / macrophages / arachidonic acid / neutrophils / mast cells / 遅発相 / 即時相 / ホスホリバーゼA_2 / サイトカイン / プロスタノイド / シクロオキシゲナーゼ / ホスホリパーゼA_2 / マクロファージ / アラキドン酸代謝 / 好中球 / 肥満細胞 Less
  • Research Projects

    (5 results)
  • Co-Researchers

    (16 People)
  •  Functional coupling of arachidonate metabolizing enzymesPrincipal Investigator

    • Principal Investigator
      OH-ISHI Sachiko
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      応用薬理学・医療系薬学
    • Research Institution
      Kitasato University
  •  Studies on the regulation of arachidonic acid metabolism using mast cells and neutrophils as model systems

    • Principal Investigator
      KUDO Ichiro
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Biological pharmacy
    • Research Institution
      Showa University
  •  STUDIES ON THE KALLIKREIN-KININ SYSTEM : ANALYSIS USING THE GENETICALLY KININOGEN-DEFICIENT RATSPrincipal Investigator

    • Principal Investigator
      OH-ISHI Sachiko
    • Project Period (FY)
      1992 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      KITASATO UNIVERSITY
  •  Biological role of kininogens; Studies using kininogen deficient rats.Principal Investigator

    • Principal Investigator
      OH-ISHI Sachiko
    • Project Period (FY)
      1987 – 1989
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      Kitasato University, School of Pharm.Sci.
  •  The mechanism of the initiation ractions for the intrinsic blood coagulation,kinin release and fibrinolysis: the activation mechanism of the precursor of serine proteases by negatively-charged surfaces and gheir biological significance.

    • Principal Investigator
      KATO Hisao
    • Project Period (FY)
      1986 – 1987
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      物質生物化学
    • Research Institution
      National Cardiovascular Center Research Institute
  • 1.  UTSUNOMIYA Iku (70168722)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 2.  YAMAKI Kohji (70174597)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 3.  HAYASHI Izumi (90172999)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  UENO Akinori (00112657)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  KUDO Ichiro (30134612)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  NARABA Hiroaki (90296517)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  MURAKAMI Makoto (60276607)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  KATO Hisao (80029959)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  MATSUDA Takehisa (60142189)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  ENJYOJI Kei-ichi (00194027)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  HAYASHI Masahiko (20164965)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  三田 征治 (90200039)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  IKEDA Yuri (10306657)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  彌益 暁子 (80174697)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  KITAGUCHI Nobuya
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  KAMIMURA Takashi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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