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OH-ISHI Sachiko
大石 幸子
Connect your ORCID iD
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Researcher Number
70050416
Affiliation (based on the past Project Information)
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1992 – 1999: 北里大学, 薬学部, 教授
1986 – 1989: 北里大学, 薬学部, 教授
1987: 北里大学, 薬学部・薬理学教室, 教授
Review Section/Research Field
Principal Investigator
Biological pharmacy
/
応用薬理学・医療系薬学
Except Principal Investigator
Biological pharmacy
/
物質生物化学
Keywords
Principal Investigator
キニノゲン欠損ラット / 高分子キニノゲン / 低分子キニノゲン / ブラジキニン / カリクレイン・キニン系 / カラゲニン胸膜炎 / エンドトキシン / PGE2 / キニノゲン / 点変異
…
More
/ 分泌異常 / 一アミノ酸変異 / 尿キニン / B / N・KatholieK rat / ブラウン・ノルウェイ・ラット / ワンポイントミューテーション / Brown Norway rat / 高血圧 / ブラジキニン・アンタゴニスト / 血管透過性亢進 / KININOGEN / KININOGEN-DEFICIENT RAT / A POINT MUTATION / SECRETION DEFECT / HIGH MOLECULAR WEIGHT KININOGEN / LLOW MOLECULAR WEIGHT KININOGEN / BRADYKININ / アラキドン酸 / COX-2 / PGE合成酵素 / PGI2 / マクロファージ / PGI_2 / ホスホリパーゼA_2 / シクロオキシゲナーゼ-1 / シクロオキシゲナーゼ-2 / プロスタグランジンE_2 / プロスタグランジンD_2 / トロンボキサンB_2 / リポポリサッカライド / Arachidonate Metabolites / Prostaglandins / Cyclooxygenase / PDE synthase / Inducible enzyme / Macrophages / T-キニノゲン / 炎症反応 / アラキドン酸代謝物 / ラジオイムノアッセイ / Tーキニノゲン / 急性相蛋白質 / 性差 / カプトプリル / カラゲニン足浮腫 / HMW-kininogen / LMW-kininogen / T-kininogen / Inflammation / Rat pleurisy / Kininogen-deficient rat / Eicosanoids / Radioimmunoassay
…
More
Except Principal Investigator
PAF / 肥満細胞 / 好中球 / アラキドン酸代謝 / マクロファージ / ホスホリパーゼA_2 / シクロオキシゲナーゼ / プロスタノイド / サイトカイン / ホスホリバーゼA_2 / 即時相 / 遅発相 / mast cells / neutrophils / arachidonic acid / macrophages / phospholipase A_2 / cyclooxygenase / prostaglandin / 血液凝固 / 開始反応 / キニン / 線溶系 / 接触反応 / Blood coagulation / initiation reaction / kinin release
Less
Research Projects
(
5
results)
Co-Researchers
(
16
People)
Project Start Year (Newest)
Project Start Year (Oldest)
Functional coupling of arachidonate metabolizing enzymes
Principal Investigator
Principal Investigator
OH-ISHI Sachiko
Project Period (FY)
1997 – 1999
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
応用薬理学・医療系薬学
Research Institution
Kitasato University
Studies on the regulation of arachidonic acid metabolism using mast cells and neutrophils as model systems
Principal Investigator
KUDO Ichiro
Project Period (FY)
1995 – 1997
Research Category
Grant-in-Aid for Scientific Research (A)
Research Field
Biological pharmacy
Research Institution
Showa University
STUDIES ON THE KALLIKREIN-KININ SYSTEM : ANALYSIS USING THE GENETICALLY KININOGEN-DEFICIENT RATS
Principal Investigator
Principal Investigator
OH-ISHI Sachiko
Project Period (FY)
1992 – 1994
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
Biological pharmacy
Research Institution
KITASATO UNIVERSITY
Biological role of kininogens; Studies using kininogen deficient rats.
Principal Investigator
Principal Investigator
OH-ISHI Sachiko
Project Period (FY)
1987 – 1989
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
Biological pharmacy
Research Institution
Kitasato University, School of Pharm.Sci.
The mechanism of the initiation ractions for the intrinsic blood coagulation,kinin release and fibrinolysis: the activation mechanism of the precursor of serine proteases by negatively-charged surfaces and gheir biological significance.
Principal Investigator
KATO Hisao
Project Period (FY)
1986 – 1987
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
物質生物化学
Research Institution
National Cardiovascular Center Research Institute
# of Projects (Dsc)
# of Projects (Asc)
1.
UTSUNOMIYA Iku
(70168722)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
2.
YAMAKI Kohji
(70174597)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
3.
HAYASHI Izumi
(90172999)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
4.
UENO Akinori
(00112657)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
5.
KUDO Ichiro
(30134612)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
6.
NARABA Hiroaki
(90296517)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
7.
MURAKAMI Makoto
(60276607)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
8.
KATO Hisao
(80029959)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
9.
MATSUDA Takehisa
(60142189)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
10.
ENJYOJI Kei-ichi
(00194027)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
11.
HAYASHI Masahiko
(20164965)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
12.
三田 征治
(90200039)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
13.
IKEDA Yuri
(10306657)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
14.
彌益 暁子
(80174697)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
15.
KITAGUCHI Nobuya
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
16.
KAMIMURA Takashi
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
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