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KUNUGI Shigeru  功刀 滋

ORCIDConnect your ORCID iD *help
… Alternative Names

功刃 滋  クヌギ シゲル

功刀 滋  クヌギ シゲル

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Researcher Number 70111929
Other IDs
External Links
Affiliation (based on the past Project Information) *help 2010 – 2011: 京都工芸繊維大学, 工芸科学研究科, 教授
2009: Kyoto Institute of Technology, 法人本部, 副学長
2004 – 2005: 京都工芸繊維大学, 副学長
1998 – 2003: 京都工芸繊維大学, 繊維学部, 教授
1994 – 1995: 京都工芸繊維大学, 繊維学部, 教授 … More
1990 – 1992: Kyoto Institute of Technology, Faculty of Textile Science Professor, 繊維学部, 教授
1987 – 1989: 福井大学, 工学部, 助教授
1985: 福井大学, 工, 助教授 Less
Review Section/Research Field
Principal Investigator
Chemistry related to living body / 生物・生体工学 / 高分子合成 / 高分子構造・物性(含繊維) / 高分子合成 / 高分子物性
Except Principal Investigator
高分子構造・物性(含繊維)
Keywords
Principal Investigator
高圧力 / 高圧 / タンパク質 / 高次構造 / High pressure / 有機溶媒 / プロテアーゼ / 分子認識 / 化学修飾 / オルガネラ … More / 生体膜 / High Pressure / 人工条件 / Chemical Modification / 酵素 / 低温変性 / アミノ酸置換 / 蛍光 / 酵素活性 / 変性 / 生体高分子 / 差分化修飾 / モデル / 構造化 / 膜タンパク質 / Organic Solvent / Cotrol of Function / Polypeptides / Enzyme / 加水分解 / 圧力依存性 / ペプチド合成 / サーモライシン / カルボキシペプチダーゼ / 高pH / 高塩濃度 / 圧力 / 機能制御 / ポリペプチド / Chaperone / Refolding / Synthetic polymer / Protein / シャペロン / 高次構造修復 / 合成高分子 / Photofuctinality / Polymer Blends / Block-copolymerization / Polymer Films / Polymer Gels / Dymanics / Polymer Materials / Self-organixation / 光機能化 / 高分子ブレンド / ブロック共重合 / 高分子フィルム / 高分子ゲル / ダイナミズム / 高分子材料 / 自己組織化 / Designed polypeptide / Structural change / Artificial conditions / Higher-order structures / Thermoresponsive polymers / Bio-model polymers / 繰り返し配列ポリペプチド / 構造変化 / 感温性高分子 / バイオモデル高分子 / Organic Solvents / Screening Procedures / Artificial Conditions / Induction / High Temperature / Tolerant Enzyme / スクリーニング / 誘導 / 高温 / 耐性酵素 / Proteins / Denaturation / Nucleases / Proteoses / Biopolymers / 電子伝達 / タンパク質分解酵素 / ヌクレア-ゼ / プロテア-ゼ / 固定化 / プレポリマー / アクリルアミドゲル / バクテリオロドプシン / 電場 / 再構成 / 薄膜 / 応答挙動 / ポリアクリルアミド / 異方性 / 非対称性 / 荷電膜 / 固定化酵素 / 酵素膜 / 蛍光プローブ / 塩基性ペプチド / 細胞内移送 / リガーゼ / トポイソメラーゼ / 超螺旋 / 安定性 / 高次構造転移 / 核酸 / 生体モデル高分子 / フレキシビリティー / 部位特異的蛍光標識 / システイン / クレアチンキナーゼ / 蛋白質 / メディエーター / 液晶 / ブロテアーゼ / メディエ-タ- / 牛血清アルブミン / 酸化還元酵素 / バクテリオロプシン / 配向化 … More
Except Principal Investigator
超分子構造 / ポリアクリロニトリル系ゲル繊維 / 人工筋肉材料 / 光制御機能 / microemulsion / poly(N-isopropyl acrylamide) / polyampholyte / high pressure / dynamic light scattering / small-angle neutron scattering / micelle / gel / 両親媒性高分子 / マイクロエマルション / ポリ(N-イソプロピルアクリルアミド) / 両新媒性高分子 / 高圧物性 / 動的光散乱 / 小角中性子散乱 / ミセル / ゲル / バクテリオロドプシンの配向 / 生体膜のエネルギー変換系 / NAD再生とアルコール脱水素酵素反応との共役 / 固定化酵素-半導体系 / バクテリオロドプシン / 生体膜エネルギー変換系 / 固定化酵素 / 光感応性物質 Less
  • Research Projects

    (21 results)
  • Research Products

    (14 results)
  • Co-Researchers

    (18 People)
  •  Intracellular protein delivery by high pressure modulationPrincipal Investigator

    • Principal Investigator
      KUNUGI Shigeru
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Chemistry related to living body
    • Research Institution
      Kyoto Institute of Technology
  •  Development of new restoration system for functional structures of proteinsPrincipal Investigator

    • Principal Investigator
      KUNUGI Shigeru
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Chemistry related to living body
    • Research Institution
      Kyoto Institute of Technology
  •  Pressure Effects on the Structure and Dynamics of Soft Condensed Matter

    • Principal Investigator
      SHIBAYAMA Mitsuhiro
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      高分子構造・物性(含繊維)
    • Research Institution
      The University of Tokyo
  •  酵素反応をメモリー装置とする核酸の超高次構造転移の解析Principal Investigator

    • Principal Investigator
      功刀 滋
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      生物・生体工学
    • Research Institution
      Kyoto Institute of Technology
  •  タンパク質のフレキシビリティーが標的分子認識機能において果す役割の解析とその制御Principal Investigator

    • Principal Investigator
      功刀 滋
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Kyoto Institute of Technology
  •  タンパク質フレキシビリティーが標的認識分子機能において果す役割の解析とその制御Principal Investigator

    • Principal Investigator
      功刀 滋
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Kyoto Institute of Technology
  •  Formation and Control of Higher-order Functional Structures of Biomodel PolymersPrincipal Investigator

    • Principal Investigator
      KUNUGI Shigeru
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      高分子合成
    • Research Institution
      Kyoto Institute of Technology
  •  Dynamic Studies of Self-organizing Polymeric MaterialsPrincipal Investigator

    • Principal Investigator
      KUNUGI Shigeru
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      高分子構造・物性(含繊維)
    • Research Institution
      Kyoto Institute of Technology
  •  タンパク質のフレキシビリティーが標的分子認識機能において果す役割の解析とその制御Principal Investigator

    • Principal Investigator
      功刀 滋
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Kyoto Institute of Technology
  •  DEVELOPMENTS OF ENZYME SYSTEMS TOLERANT TO ARTIFICIAL CONDITIONS AND ANALYSIS OF THEIR FUNCTIONSPrincipal Investigator

    • Principal Investigator
      KUNUGI Shigeru
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      生物・生体工学
    • Research Institution
      KYOTO INSTITUTE OF TECHNOLOGY
  •  差分化修飾によって調製した生体高分子性メディエーターの反応特性Principal Investigator

    • Principal Investigator
      功刃 滋
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto Institute of Technology
  •  差分化修飾によって調製した生体高分子性メディエーターの反応特性Principal Investigator

    • Principal Investigator
      功刀 滋
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto Institute of Technology
  •  構造化された生体膜・オルガネラモデル系における機能発現Principal Investigator

    • Principal Investigator
      功刀 滋
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto Institute of Technology
  •  構造化された生体膜・オルガネラモデル系における機能発現Principal Investigator

    • Principal Investigator
      功刀 滋
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto Institute of Technology
  •  構造化された生体膜・オルガネラモデル系における機能発現Principal Investigator

    • Principal Investigator
      功刀 滋
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto Institute of Technology
  •  エネルギー変換機能をもつ材料の構築に関する研究

    • Principal Investigator
      田中 渥夫
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto University
  •  Biopolymer Functions under High PressurePrincipal Investigator

    • Principal Investigator
      KUNUGI Shigeru
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      高分子物性
    • Research Institution
      Kyoto Institute of Technology
      University of Fukui
  •  エネルギー変換機能をもつ材料の構築に関する研究

    • Principal Investigator
      田中 渥夫
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto University
  •  超分子構造を制御した生体素子を有する機能性材料の設計Principal Investigator

    • Principal Investigator
      功刀 滋
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      University of Fukui
  •  New Synthesis of Polypeptides by Enzyme Systems Cotrolled by Chemical and Physical MethodsPrincipal Investigator

    • Principal Investigator
      KUNUGI Shigeru
    • Project Period (FY)
      1987 – 1988
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      高分子合成
    • Research Institution
      Fukui University
  •  非対称荷電中に配向したタンパク質を有する薄膜の合成とその応答挙動Principal Investigator

    • Principal Investigator
      功刀 滋
    • Project Period (FY)
      1985
    • Research Category
      Grant-in-Aid for Special Project Research
    • Research Institution
      University of Fukui

All 2011 2006 2005 Other

All Journal Article

  • [Journal Article] The mechanism of fibril formation of a non-inhibitory serpin ovalbumin revealed by the identification of amyloidogenic core regions2011

    • Author(s)
      N.Tanaka, Y.Morimoto, Y.Noguchi, T.Tada, T.Waku, S.Kunugi, T.Morii, Y-F.Lee, T.Konno, N.Takahashi
    • Journal Title

      The Journal of Biological Chemistry

      Volume: 286 Pages: 5884-5894

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21550154
  • [Journal Article] The Mechanism of Fibril Formation of a Non-inhibitory Serpin Ovalbumin Revealed by the Identification of Amyloidogenic Core Regions2011

    • Author(s)
      Naoti Tanaka, Yumi Morimoto, Yurika Noguchi, Tomoko Tada, Tomonori Waku, Shigeru Kunugi, Takashi Morii, Yin-Fai Lee, Takashi Konno, Nobuyuki Takahashi
    • Journal Title

      The Journal of Biological Chemistry

      Volume: 286 Issue: 7 Pages: 5884-5894

    • DOI

      10.1074/jbc.m110.176396

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21550154
  • [Journal Article] The mechanism of fibril formation of a non-inhibitory serpin ovalbumin revealed by the identification of amyloidogenic core regions2011

    • Author(s)
      Tanaka N., Morimoto Y., Noguchi Y., Tada T., Waku T., Kunugi S., Morii T., Lee Y-F., Konno T., Takahashi N.
    • Journal Title

      J. Biol. Chem.

      Volume: 286 Pages: 5884-5889

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21550154
  • [Journal Article] Synergetic Effects of Pressure and Chemical Denaturant on Protein Unfolding : Stability of a Serine-type Carboxyl Protease, kumamolisin2006

    • Author(s)
      Fujimoto Y., Ikeuchi H., Tada T., Oyama H., Oda K., Kunugi S.
    • Journal Title

      Biochim.Biophys.Acta Proteins & Proteomics (in press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15350103
  • [Journal Article] Synergetic Effects of Pressure and Chemical Denaturant on Protein Unfolding :Stability of a Serine-type Carboxyl Protease, kumamolisin2006

    • Author(s)
      Fujimoto Y., Ikeuchi H., Tada T., Oyama H., Oda K., Kunugi S.
    • Journal Title

      Biochim.Biophys.Acta Proteins & Proteomics doi:10.1016/j.bba pap.2005.12.010(in press)

    • Data Source
      KAKENHI-PROJECT-15350103
  • [Journal Article] Pre-incubation under High Pressure Accelerates Amyloid Formation from Insulin.2006

    • Author(s)
      Fujimoto Y., Tanaka N., Kunugi S.
    • Journal Title

      Polymer J. 38(3)

      Pages: 302-305

    • NAID

      10017315208

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15350103
  • [Journal Article] Pre-incubation under High Pressure Accelerates Amyloid Formation from Insulin2006

    • Author(s)
      Fujimoto Y., Tanaka N., Kunugi S.
    • Journal Title

      Polymer J. 38(3)

      Pages: 302-305

    • NAID

      10017315208

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15350103
  • [Journal Article] Synergetic Effects of Pressure and Chemical Denaturant on Protein Unfolding : Stability of a Serine-type Carboxyl Protease, kumamolisin.2006

    • Author(s)
      Fujimoto Y., Ikeuchi H., Tada T., Oyama H., Oda K., Kunugi S.
    • Journal Title

      Biochim.Biophys.Acta Proteins & Proteomics (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15350103
  • [Journal Article] Differences in the Pressure and Temperature Transitions : Proteins and Polymer Gels.2005

    • Author(s)
      Kunugi S., Kameyama K., Tada T., Tanaka N., Shibayama M., Akashi M.
    • Journal Title

      Braz.J.Med.Biol.Res. 38(8)

      Pages: 1233-1238

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15350103
  • [Journal Article] Temperature- and pressure-responsive properties of L- and DL- forms of poly(N-(1-hydroxymethyl)propylmethacrylamide in aqueous solutions2005

    • Author(s)
      Seto Y., Aoki T., Kunugi S.
    • Journal Title

      Colloid Polym.Sci. 283(10)

      Pages: 1137-1142

    • Data Source
      KAKENHI-PROJECT-15350103
  • [Journal Article] Temperature- and pressure-responsive properties of L- and DL- forms of poly(N-(1-hydroxymethyl)propylmethacrylamide in aqueous solutions2005

    • Author(s)
      Seto Y., Aoki, T., Kunugi S.
    • Journal Title

      Colloid Polym.Sci. 283(10)

      Pages: 1137-1142

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15350103
  • [Journal Article] Temperature- and pressure-responsive properties of L- and DL- forms of poly(N-(1-hydroxymethyl) propylmethacrylamide in aqueous solutions.2005

    • Author(s)
      Seto Y., Aoki T., Kunugi S.
    • Journal Title

      Colloid Polym.Sci. 283(10)

      Pages: 1137-1142

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15350103
  • [Journal Article] Differences in the Pressure and Temperature Transitions :Proteins and Polymer Gels.2005

    • Author(s)
      Kunugi S., Kameyama K., Tada T., Tanaka N., Shibayama M., Akashi M.
    • Journal Title

      Braz.J.Med.Biol.Res. 38(8)

      Pages: 1233-1238

    • Data Source
      KAKENHI-PROJECT-15350103
  • [Journal Article] Differences in the Pressure and Temperature Transitions : Proteins and Polymer Gels

    • Author(s)
      Kunugi S.
    • Journal Title

      Brazilian Journal of Biology and Medicine (in press)

    • Data Source
      KAKENHI-PROJECT-15350103
  • 1.  TANAKA Naoki (60243127)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 7 results
  • 2.  伊藤 伸哉 (90213066)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 3.  奥居 徳昌 (20111651)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  YAMAOKA Tetsuji (50243126)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  SHIBAYAMA Mitsuhiro (00175390)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  田中 渥夫 (80026088)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  NOMURA Akihiko (10001041)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  HIRAGA Kazumi (50252549)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  KIMURA Yoshiharu (10132276)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  SAKURAI Shinichi (90215682)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  ITAYA Akira (80035071)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  TSUTSUMI Naoto (50172036)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  MIYATA Takaaki (50188827)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  NAGAO Michihiro (90301150)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  SETO Hideki (60216546)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  吉田 絵里 (60263175)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  KAWAI Shouji
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  松本 雅光
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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