KUNUGI Shigeru 功刀滋

… Alternative Names

功刃滋クヌギシゲル

功刀滋クヌギシゲル

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Researcher Number	70111929
Other IDs
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Affiliation (based on the past Project Information) *help	2010 – 2011: 京都工芸繊維大学, 工芸科学研究科, 教授 2009: Kyoto Institute of Technology, 法人本部, 副学長 2004 – 2005: 京都工芸繊維大学, 副学長 1998 – 2003: 京都工芸繊維大学, 繊維学部, 教授 1994 – 1995: 京都工芸繊維大学, 繊維学部, 教授 … More 1990 – 1992: Kyoto Institute of Technology, Faculty of Textile Science Professor, 繊維学部, 教授 1987 – 1989: 福井大学, 工学部, 助教授 1985: 福井大学, 工, 助教授 Less
Review Section/Research Field	Principal Investigator 生物・生体工学 / Chemistry related to living body / 高分子物性 / 高分子合成 / 高分子構造・物性(含繊維) / 高分子合成 Except Principal Investigator 高分子構造・物性(含繊維)
Keywords	Principal Investigator 高圧力 / 高圧 / 高次構造 / タンパク質 / 生体膜 / オルガネラ / 化学修飾 / 分子認識 / プロテアーゼ / 有機溶媒 … More / High pressure / 膜タンパク質 / 構造化 / モデル / 差分化修飾 / 生体高分子 / 変性 / 酵素活性 / 蛍光 / アミノ酸置換 / 低温変性 / 酵素 / Chemical Modification / 人工条件 / High Pressure / 配向化 / バクテリオロプシン / 酸化還元酵素 / 牛血清アルブミン / メディエ-タ- / ブロテアーゼ / 液晶 / メディエーター / 蛋白質 / クレアチンキナーゼ / システイン / 部位特異的蛍光標識 / フレキシビリティー / 生体モデル高分子 / 核酸 / 高次構造転移 / 安定性 / 超螺旋 / トポイソメラーゼ / リガーゼ / 細胞内移送 / 塩基性ペプチド / 蛍光プローブ / 酵素膜 / 固定化酵素 / 荷電膜 / 非対称性 / 異方性 / ポリアクリルアミド / 応答挙動 / 薄膜 / 再構成 / 電場 / バクテリオロドプシン / アクリルアミドゲル / プレポリマー / 固定化 / プロテア-ゼ / ヌクレア-ゼ / タンパク質分解酵素 / 電子伝達 / Biopolymers / Proteoses / Nucleases / Denaturation / Proteins / 耐性酵素 / 高温 / 誘導 / スクリーニング / Tolerant Enzyme / High Temperature / Induction / Artificial Conditions / Screening Procedures / Organic Solvents / バイオモデル高分子 / 感温性高分子 / 構造変化 / 繰り返し配列ポリペプチド / Bio-model polymers / Thermoresponsive polymers / Higher-order structures / Artificial conditions / Structural change / Designed polypeptide / 自己組織化 / 高分子材料 / ダイナミズム / 高分子ゲル / 高分子フィルム / ブロック共重合 / 高分子ブレンド / 光機能化 / Self-organixation / Polymer Materials / Dymanics / Polymer Gels / Polymer Films / Block-copolymerization / Polymer Blends / Photofuctinality / 合成高分子 / 高次構造修復 / シャペロン / Protein / Synthetic polymer / Refolding / Chaperone / ポリペプチド / 機能制御 / 圧力 / 高塩濃度 / 高pH / カルボキシペプチダーゼ / サーモライシン / ペプチド合成 / 圧力依存性 / 加水分解 / Enzyme / Polypeptides / Cotrol of Function / Organic Solvent … More Except Principal Investigator 光制御機能 / 人工筋肉材料 / ポリアクリロニトリル系ゲル繊維 / 超分子構造 / 光感応性物質 / 固定化酵素 / 生体膜エネルギー変換系 / バクテリオロドプシン / 固定化酵素-半導体系 / NAD再生とアルコール脱水素酵素反応との共役 / 生体膜のエネルギー変換系 / バクテリオロドプシンの配向 / ゲル / ミセル / 小角中性子散乱 / 動的光散乱 / 高圧物性 / 両新媒性高分子 / ポリ(N-イソプロピルアクリルアミド) / マイクロエマルション / 両親媒性高分子 / gel / micelle / small-angle neutron scattering / dynamic light scattering / high pressure / polyampholyte / poly(N-isopropyl acrylamide) / microemulsion Less

Intracellular protein delivery by high pressure modulationPrincipal Investigator
- Principal Investigator
  
  KUNUGI Shigeru
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemistry related to living body
- Research Institution
  Kyoto Institute of Technology
Development of new restoration system for functional structures of proteinsPrincipal Investigator
- Principal Investigator
  
  KUNUGI Shigeru
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Chemistry related to living body
- Research Institution
  Kyoto Institute of Technology
Pressure Effects on the Structure and Dynamics of Soft Condensed Matter
- Principal Investigator
  
  SHIBAYAMA Mitsuhiro
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  高分子構造・物性(含繊維)
- Research Institution
  The University of Tokyo
酵素反応をメモリー装置とする核酸の超高次構造転移の解析Principal Investigator
- Principal Investigator
  
  功刀滋
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  生物・生体工学
- Research Institution
  Kyoto Institute of Technology
タンパク質のフレキシビリティーが標的分子認識機能において果す役割の解析とその制御Principal Investigator
- Principal Investigator
  
  功刀滋
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kyoto Institute of Technology
タンパク質フレキシビリティーが標的認識分子機能において果す役割の解析とその制御Principal Investigator
- Principal Investigator
  
  功刀滋
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kyoto Institute of Technology
Formation and Control of Higher-order Functional Structures of Biomodel PolymersPrincipal Investigator
- Principal Investigator
  
  KUNUGI Shigeru
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  高分子合成
- Research Institution
  Kyoto Institute of Technology
Dynamic Studies of Self-organizing Polymeric MaterialsPrincipal Investigator
- Principal Investigator
  
  KUNUGI Shigeru
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  高分子構造・物性(含繊維)
- Research Institution
  Kyoto Institute of Technology
タンパク質のフレキシビリティーが標的分子認識機能において果す役割の解析とその制御Principal Investigator
- Principal Investigator
  
  功刀滋
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kyoto Institute of Technology
DEVELOPMENTS OF ENZYME SYSTEMS TOLERANT TO ARTIFICIAL CONDITIONS AND ANALYSIS OF THEIR FUNCTIONSPrincipal Investigator
- Principal Investigator
  
  KUNUGI Shigeru
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  生物・生体工学
- Research Institution
  KYOTO INSTITUTE OF TECHNOLOGY
差分化修飾によって調製した生体高分子性メディエーターの反応特性Principal Investigator
- Principal Investigator
  
  功刃滋
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto Institute of Technology
差分化修飾によって調製した生体高分子性メディエーターの反応特性Principal Investigator
- Principal Investigator
  
  功刀滋
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto Institute of Technology
構造化された生体膜・オルガネラモデル系における機能発現Principal Investigator
- Principal Investigator
  
  功刀滋
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto Institute of Technology
構造化された生体膜・オルガネラモデル系における機能発現Principal Investigator
- Principal Investigator
  
  功刀滋
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto Institute of Technology
構造化された生体膜・オルガネラモデル系における機能発現Principal Investigator
- Principal Investigator
  
  功刀滋
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto Institute of Technology
エネルギー変換機能をもつ材料の構築に関する研究
- Principal Investigator
  
  田中渥夫
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
Biopolymer Functions under High PressurePrincipal Investigator
- Principal Investigator
  
  KUNUGI Shigeru
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  高分子物性
- Research Institution
  Kyoto Institute of Technology
  University of Fukui
エネルギー変換機能をもつ材料の構築に関する研究
- Principal Investigator
  
  田中渥夫
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
超分子構造を制御した生体素子を有する機能性材料の設計Principal Investigator
- Principal Investigator
  
  功刀滋
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  University of Fukui
New Synthesis of Polypeptides by Enzyme Systems Cotrolled by Chemical and Physical MethodsPrincipal Investigator
- Principal Investigator
  
  KUNUGI Shigeru
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  高分子合成
- Research Institution
  Fukui University
非対称荷電中に配向したタンパク質を有する薄膜の合成とその応答挙動Principal Investigator
- Principal Investigator
  
  功刀滋
- Project Period (FY)
  1985
- Research Category
  
  Grant-in-Aid for Special Project Research
- Research Institution
  University of Fukui

All 2011 2006 2005 Other

All Journal Article

[Journal Article] The mechanism of fibril formation of a non-inhibitory serpin ovalbumin revealed by the identification of amyloidogenic core regions2011
- Author(s)
  N.Tanaka, Y.Morimoto, Y.Noguchi, T.Tada, T.Waku, S.Kunugi, T.Morii, Y-F.Lee, T.Konno, N.Takahashi
- Journal Title
  
  The Journal of Biological Chemistry
  
  Volume: 286 Pages: 5884-5894
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21550154
[Journal Article] The Mechanism of Fibril Formation of a Non-inhibitory Serpin Ovalbumin Revealed by the Identification of Amyloidogenic Core Regions2011
- Author(s)
  Naoti Tanaka, Yumi Morimoto, Yurika Noguchi, Tomoko Tada, Tomonori Waku, Shigeru Kunugi, Takashi Morii, Yin-Fai Lee, Takashi Konno, Nobuyuki Takahashi
- Journal Title
  
  The Journal of Biological Chemistry
  
  Volume: 286 Pages: 5884-5894
- DOI
  10.1074/jbc.m110.176396
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21550154
[Journal Article] The mechanism of fibril formation of a non-inhibitory serpin ovalbumin revealed by the identification of amyloidogenic core regions2011
- Author(s)
  Tanaka N., Morimoto Y., Noguchi Y., Tada T., Waku T., Kunugi S., Morii T., Lee Y-F., Konno T., Takahashi N.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 286 Pages: 5884-5889
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21550154
[Journal Article] Synergetic Effects of Pressure and Chemical Denaturant on Protein Unfolding : Stability of a Serine-type Carboxyl Protease, kumamolisin2006
- Author(s)
  Fujimoto Y., Ikeuchi H., Tada T., Oyama H., Oda K., Kunugi S.
- Journal Title
  
  Biochim.Biophys.Acta Proteins & Proteomics (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15350103
[Journal Article] Synergetic Effects of Pressure and Chemical Denaturant on Protein Unfolding :Stability of a Serine-type Carboxyl Protease, kumamolisin2006
- Author(s)
  Fujimoto Y., Ikeuchi H., Tada T., Oyama H., Oda K., Kunugi S.
- Journal Title
  
  Biochim.Biophys.Acta Proteins & Proteomics doi:10.1016/j.bba pap.2005.12.010(in press)
- Data Source
  KAKENHI-PROJECT-15350103
[Journal Article] Pre-incubation under High Pressure Accelerates Amyloid Formation from Insulin.2006
- Author(s)
  Fujimoto Y., Tanaka N., Kunugi S.
- Journal Title
  
  Polymer J. 38(3)
  
  Pages: 302-305
- NAID
  10017315208
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15350103
[Journal Article] Pre-incubation under High Pressure Accelerates Amyloid Formation from Insulin2006
- Author(s)
  Fujimoto Y., Tanaka N., Kunugi S.
- Journal Title
  
  Polymer J. 38(3)
  
  Pages: 302-305
- NAID
  10017315208
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15350103
[Journal Article] Synergetic Effects of Pressure and Chemical Denaturant on Protein Unfolding : Stability of a Serine-type Carboxyl Protease, kumamolisin.2006
- Author(s)
  Fujimoto Y., Ikeuchi H., Tada T., Oyama H., Oda K., Kunugi S.
- Journal Title
  
  Biochim.Biophys.Acta Proteins & Proteomics (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15350103
[Journal Article] Differences in the Pressure and Temperature Transitions : Proteins and Polymer Gels.2005
- Author(s)
  Kunugi S., Kameyama K., Tada T., Tanaka N., Shibayama M., Akashi M.
- Journal Title
  
  Braz.J.Med.Biol.Res. 38(8)
  
  Pages: 1233-1238
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15350103
[Journal Article] Temperature- and pressure-responsive properties of L- and DL- forms of poly(N-(1-hydroxymethyl)propylmethacrylamide in aqueous solutions2005
- Author(s)
  Seto Y., Aoki T., Kunugi S.
- Journal Title
  
  Colloid Polym.Sci. 283(10)
  
  Pages: 1137-1142
- Data Source
  KAKENHI-PROJECT-15350103
[Journal Article] Temperature- and pressure-responsive properties of L- and DL- forms of poly(N-(1-hydroxymethyl)propylmethacrylamide in aqueous solutions2005
- Author(s)
  Seto Y., Aoki, T., Kunugi S.
- Journal Title
  
  Colloid Polym.Sci. 283(10)
  
  Pages: 1137-1142
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15350103
[Journal Article] Temperature- and pressure-responsive properties of L- and DL- forms of poly(N-(1-hydroxymethyl) propylmethacrylamide in aqueous solutions.2005
- Author(s)
  Seto Y., Aoki T., Kunugi S.
- Journal Title
  
  Colloid Polym.Sci. 283(10)
  
  Pages: 1137-1142
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15350103
[Journal Article] Differences in the Pressure and Temperature Transitions :Proteins and Polymer Gels.2005
- Author(s)
  Kunugi S., Kameyama K., Tada T., Tanaka N., Shibayama M., Akashi M.
- Journal Title
  
  Braz.J.Med.Biol.Res. 38(8)
  
  Pages: 1233-1238
- Data Source
  KAKENHI-PROJECT-15350103
[Journal Article] Differences in the Pressure and Temperature Transitions : Proteins and Polymer Gels
- Author(s)
  Kunugi S.
- Journal Title
  
  Brazilian Journal of Biology and Medicine (in press)
- Data Source
  KAKENHI-PROJECT-15350103

1. TANAKA Naoki (60243127)

# of Collaborated Projects: 8 results

# of Collaborated Products: 7 results
2. 伊藤伸哉 (90213066)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. 奥居徳昌 (20111651)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. YAMAOKA Tetsuji (50243126)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. SHIBAYAMA Mitsuhiro (00175390)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 田中渥夫 (80026088)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. NOMURA Akihiko (10001041)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. HIRAGA Kazumi (50252549)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. KIMURA Yoshiharu (10132276)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. SAKURAI Shinichi (90215682)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. ITAYA Akira (80035071)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. TSUTSUMI Naoto (50172036)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. MIYATA Takaaki (50188827)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. NAGAO Michihiro (90301150)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. SETO Hideki (60216546)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 吉田絵里 (60263175)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. KAWAI Shouji

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 松本雅光

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

KUNUGI Shigeru 功刀 滋

功刃 滋 クヌギ シゲル

功刀 滋 クヌギ シゲル

Research Projects

Research Products

Co-Researchers

Intracellular protein delivery by high pressure modulationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of new restoration system for functional structures of proteinsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Pressure Effects on the Structure and Dynamics of Soft Condensed Matter

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

酵素反応をメモリー装置とする核酸の超高次構造転移の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

タンパク質のフレキシビリティーが標的分子認識機能において果す役割の解析とその制御Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

タンパク質フレキシビリティーが標的認識分子機能において果す役割の解析とその制御Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Formation and Control of Higher-order Functional Structures of Biomodel PolymersPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Dynamic Studies of Self-organizing Polymeric MaterialsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

タンパク質のフレキシビリティーが標的分子認識機能において果す役割の解析とその制御Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

DEVELOPMENTS OF ENZYME SYSTEMS TOLERANT TO ARTIFICIAL CONDITIONS AND ANALYSIS OF THEIR FUNCTIONSPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

差分化修飾によって調製した生体高分子性メディエーターの反応特性Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

差分化修飾によって調製した生体高分子性メディエーターの反応特性Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

構造化された生体膜・オルガネラモデル系における機能発現Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

構造化された生体膜・オルガネラモデル系における機能発現Principal Investigator

Principal Investigator

KUNUGI Shigeru 功刀滋

功刃滋クヌギシゲル

功刀滋クヌギシゲル