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IMAWARI Michio  井廻 道夫

ORCIDConnect your ORCID iD *help
Researcher Number 70134228
External Links
Affiliation (based on the past Project Information) *help 2008: 昭和大学・医学部・教授, 医学部, 教授
2006 – 2008: 昭和大学, 医学部, 教授
2003 – 2004: Showa Univ., School of Medicine, Professor, 医学部, 教授
1993 – 2002: Jichi Medical School, Medicine, Professor, 医学部, 教授
1991 – 1992: University of Tokyo Faculty of Medicine Assistant professor, 医学部(病), 助教授 … More
1990: 東京大学, 医学部・附属病院, 講師
1989: 東京大学, 医学部(病), 講師
1988: 東京大学, 医学部, 講師
1987: ditto of Toky,Faculty of Medicine, 医学部(病), 助手
1986: 東大, 医学部(内科学), 助手
1986: 東大, 医学部, 助手
1985: 東京大学, 医学部, 助手 Less
Review Section/Research Field
Principal Investigator
Gastroenterology
Except Principal Investigator
Radiation science / Gastroenterology / Gastroenterology
Keywords
Principal Investigator
細胞障害性T細胞 / C型肝炎 / C型肝炎ウイルス / hepatitis C virus / ヘルパーT細胞 / HLAB44 / C型肝炎ウイルスコア抗原 / cytotoxic T cell / HLA B44 / HLA-A24 … More / ELISpot / epitope / cytotoxic T lymphocyte / hepatitis C / インターロイキン4 / インターフェロンγ / TNF / Fas / エピトープ / helper T cell / 肝癌 / 抗原エピトープ / interferon / インターフェロン / interleukin-10 / interleukin-4 / interferon-γ / immunology / C型肝炎ウイルスNS3蛋白 / C型肝炎ウイルスコア蛋白 / HCV抗原 / インターロイキン10 / 免疫 / DNA vaccine / インターロイン12 / ワクチン / GM-CSF / DNAワクチン / perforin / パ-フォリン / 変異 / パーフォリン / antigen epitope / Antibody / T cell receptor / Cytotoxic T cell / Hepatitis C virus / Hepatitis C / 抗体 / T細胞受容体 / tumor-associated antigen / killer T-cell / hepatoma / 細胞傷害性T細胞 / 腫瘍抗原 / キラ-T細胞 / ラット肝細胞 / 肝細胞増殖因子 / フィブロネクチンフラグメント / フィブロネクチン / 肝細胞増殖 / アポリポ蛋白 / cDNAクローニング / 先天性リポ蛋白異常症 / アポB / アポc-【III】 / アポA-【I】 / RFLP / 遺伝子 / チンパンジー / 抗原エピト-プ … More
Except Principal Investigator
MRI / HCV / Woodchuck / Tumor thrombus / Regeneration nodules / Liver cirrhosis / Hepatocellular carcinoma / 肝硬変 / MRI(核磁気共鳴CT) / MRI造形剤 / ウッドチャック / 腫瘍栓 / 再生結節 / 肝硬変症 / 肝細胞癌 / Immune response / 免疫応答 / 肝炎ウイルス / B細胞感染 / C型肝炎ウイルス / IRES依存性RNA翻訳 / リンパ増殖性疾患 / B細胞トロピズム / ウイルス / 感染症 / 消化器内科 / 内科 Less
  • Research Projects

    (16 results)
  • Research Products

    (21 results)
  • Co-Researchers

    (15 People)
  •  Analysis for mechanism of IRES dependent translation and pathogenesis of hepatitis C virus in B cells

    • Principal Investigator
      ITO Takayoshi
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Showa University
  •  Research on cytotoxic T cell responses to hepatitis C virus infectionPrincipal Investigator

    • Principal Investigator
      IMAWARI Michio
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Showa University
      Jichi Medical University
  •  The Function of HCV specific TGF-β-producing helper T cell in chronic hepatitis C patient

    • Principal Investigator
      NAKAMURA Ikuo
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      JICHI MEDICAL SCHOOL
  •  Analysis of cellular immune responses in perihperal blood and liver tissues in HCV infectionPrincipal Investigator

    • Principal Investigator
      IMAWARI Michio
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Jichi Medical School
  •  Molecular and immunological study on the pathogenesis of hepatitis CPrincipal Investigator

    • Principal Investigator
      IMAWARI Michio
    • Project Period (FY)
      1995 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Gastroenterology
    • Research Institution
      Jichi Medical School
  •  Development of T-cell vaccine for hepatitis C virusPrincipal Investigator

    • Principal Investigator
      IMAWARI Michio
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Gastroenterology
    • Research Institution
      Jichi Medical School
  •  チンパンジーにおけるC型肝炎ウイルス特異的細胞障害性T細胞応答の研究Principal Investigator

    • Principal Investigator
      井廻 道夫
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Jichi Medical University
  •  C型肝炎ウイルスの特異的細胞障害性T細胞により認識される抗原エピトープの解析Principal Investigator

    • Principal Investigator
      井廻 道夫
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      The University of Tokyo
  •  Studies on the Immunopathogenesis of Viral Hepatitis CPrincipal Investigator

    • Principal Investigator
      IMAWARI Michio
    • Project Period (FY)
      1992 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Jichi Medical School
      The University of Tokyo
  •  C型肝炎ウイルスの特異的細胞障害性T細胞により認識される抗原エピト-プの解析Principal Investigator

    • Principal Investigator
      井廻 道夫
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      The University of Tokyo
  •  Production of antibodies to inhibit the cytotoxic activities of hepatitis C virus-specific cytotoxic T cellsPrincipal Investigator

    • Principal Investigator
      IMAWARI Michio
    • Project Period (FY)
      1991 – 1993
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Jichi Medical School
      The University of Tokyo
  •  Molecular biological studies on a hepatoma-associated target antigen for a human killer T-cell clonePrincipal Investigator

    • Principal Investigator
      IMAWARI Michio
    • Project Period (FY)
      1989 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      University of Tokyo
  •  肝癌細胞株の分泌する肝細胞増殖因子の精製・純化Principal Investigator

    • Principal Investigator
      井廻 道夫
    • Project Period (FY)
      1987 – 1988
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      The University of Tokyo
  •  フィブロネクチンフラグメントの肝細胞増殖促進作用に関する研究Principal Investigator

    • Principal Investigator
      井廻 道夫
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      The University of Tokyo
  •  先天性リポ蛋白異常症におけるアポ蛋白構造遺伝子異常とその治療Principal Investigator

    • Principal Investigator
      井廻 道夫
    • Project Period (FY)
      1985
    • Research Category
      Grant-in-Aid for Special Project Research
    • Research Institution
      The University of Tokyo
  •  Diagnosis and evaluation of hepatocellular carcinoma and precancerous states using magnetic resonance imaging

    • Principal Investigator
      ITAI Yuji
    • Project Period (FY)
      1985 – 1987
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Radiation science
    • Research Institution
      University of Toky,Faculty of Medicine.

All 2009 2008 2007 2006

All Journal Article Presentation

  • [Journal Article] Infection of B Cells with Hepatitis C Virus for the Development of Lymphoproliferative2009

    • Author(s)
      Inokuchi M, Ito T, Uchikoshi M, Shimozuma Y, Morikawa K, Nozawa H,Shimazaki T,Hiroishi K, Miyakawa Y and Imawari M
    • Journal Title

      Disorders in Patients with Chronic Hepatitis C. J Med Virol.81

      Pages: 619-627

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590749
  • [Journal Article] Magnitude of CD8+ T-cell responses against hepatitis C virus and severity of hepatitis do not necessarily determine outcomes in acute hepatitis C virus infection.2009

    • Author(s)
      Doi H, Hiroishi K, Shimazaki T, Eguchi J, Baba T, Ito T, Matsumura T, Nozawa H, Morikawa K, Ishii S, Hiraide A, Sakaki M, Imawari M.
    • Journal Title

      Hepatology Research 39

      Pages: 256-265

    • NAID

      10025324889

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590749
  • [Journal Article] Infection of B Cells with Hepatitis C Virus for the Development of Lymphoproliferative Disorders in Patients with Chronic Hepatitis C.2009

    • Author(s)
      Inokuchi M, Ito T, Uchikoshi M, Shimozuma Y, Morikawa K, Nozawa H, Shimazaki T, Hiroishi K, Miyakawa Y, Imawari M.
    • Journal Title

      Journal of Medical Virology 81

      Pages: 619-627

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590749
  • [Journal Article] Magnitude of CD8+ T-cell responses against hepatitis C virus and severity of hepatitis do not necessarily determine outcomes in acute hepatitis C virus infection2009

    • Author(s)
      Doi H, Hiroishi K, Shimazaki T, Eguchi J, Baba T, Ito T, Matsumura T, Nozawa H, Morikawa K, Ishii S, Hiraide A, Sakaki M, Imawari M
    • Journal Title

      Hepatology Research 39

      Pages: 256-265

    • NAID

      10025324889

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590749
  • [Journal Article] Evaluation of Serum B Cell Activating Factor (BAFF/BlyS) as an Immunological Marker for Lymphoproliferative Disorders Associated with Chronic Hepatitis C2009

    • Author(s)
      Uchikoshi M, Ito T, Shimozuma Y, Inokuchi T, Morikawa K, Nozawa H, Shimazaki T and M. Imawari
    • Journal Title

      The Showa University Journal of Medical Sciences (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590749
  • [Journal Article] Immune responses in hepatitis C virus infection and mechanisms of hepatitis C virus persistence2008

    • Author(s)
      Hiroishi K, Ito T and Imawari M
    • Journal Title

      Journal of Gastroenterol Hepatol 23

      Pages: 1473-1482

    • Data Source
      KAKENHI-PROJECT-18590749
  • [Journal Article] Intrahepatic status of regulatory T cells in autoimmune liver disease and chronic viral hepatitis2008

    • Author(s)
      Sakaki M, Hiroishi K, Baba T, Ito T, Hirayama Y, Saito K, Tonoike T, Kushima M and Imawari M
    • Journal Title

      Hepatology Research 38

      Pages: 354-361

    • NAID

      10024147832

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590749
  • [Journal Article] Intrahepatic status of regulatory T cells in autoimmune liver disease and chronic viral hepatitis.2008

    • Author(s)
      Sakaki M, Hiroishi K, Baba T, Ito T, Hirayama Y, Saito K, Tonoike T, Kushima M, Imawari M.
    • Journal Title

      Hepatology Research 38

      Pages: 354-361

    • NAID

      10024147832

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590749
  • [Journal Article] Clonal Expansion of B cells is identified in Japanese Patients Infected with Hepatitis C virus2008

    • Author(s)
      Inokuchi T, Ito T, Uchikoshi M, Shimozuma Y, Nozawa H, Shimazaki T and Imawari M
    • Journal Title

      The Showa University Journal of Medical Sciences 23

      Pages: 29-39

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590749
  • [Journal Article] Immune responses in hepatitis C virus infection and mechanisms of hepatitis C virus persistence.2008

    • Author(s)
      Hiroishi K, Ito T, Imawari M.
    • Journal Title

      Journal of Gastroenterol Hepatology 23

      Pages: 1473-1482

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590749
  • [Presentation] Infection of B Cells with Hepatitis C Virus for the Development of Lymphoproliferative Disorders in Patients with Chronic Hepatitis C.2008

    • Author(s)
      Inokuchi M, Ito T, Uchikoshi M, Shimozuma Y, Morikawa K, Nozawa H, Shimazaki T, Hiroishi K, Imawari M.
    • Organizer
      59th Annual Meeting of the American Association for the Study of Liver Disease
    • Place of Presentation
      San Francisco, USA
    • Data Source
      KAKENHI-PROJECT-18590749
  • [Presentation] C型慢性肝炎患者におけるB細胞HCV感染とリンパ増殖性疾患発症についての検討2008

    • Author(s)
      井口桃子, 伊藤敬義, 森川賢一, 打越学, 野沢妃佐子, 島崎とも江, 井廻道夫
    • Organizer
      第94回日本消化器病学会総会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-18590749
  • [Presentation] HCV関連リンパ増殖性疾患における血清B細胞増殖因子(BAFF/BLyS)2008

    • Author(s)
      打越学, 伊藤敬義, 井口桃子, 森川賢一, 下間祐, 井廻道夫
    • Organizer
      第44回日本肝臓学会総会
    • Place of Presentation
      松山
    • Data Source
      KAKENHI-PROJECT-18590749
  • [Presentation] Infection of B Cells with Hepatitis C Virus for the Development of Lymphoproliferative Disorders in Patients with Chronic Hepatitis C2008

    • Author(s)
      Inokuchi M, Ito T, Uchikoshi M, Shimozuma Y, Nozawa H, Shimazaki T, Hiroishi K, Miyakawa Y and Imawari M
    • Organizer
      59th Annual Meeting of the American Association for the Study of Liver Disease
    • Place of Presentation
      San Francisco
    • Data Source
      KAKENHI-PROJECT-18590749
  • [Presentation] Evaluation of Serum B Cell Activating Factor (BAFF/BlyS)as an Immunological Marker for Lymphoproliferative Disorders Associated with Chronic Hepatitis C.2008

    • Author(s)
      Uchikoshi M, Ito T, Shimozuma Y, Inokuchi T, Morikawa K, Nozawa H, Shimazaki T, M, Imawari.
    • Organizer
      59th Annual Meeting of the American Association for the Study of Liver Diseas
    • Place of Presentation
      San Francisco, USA
    • Data Source
      KAKENHI-PROJECT-18590749
  • [Presentation] Evaluation of Serum B Cell Activating Factor (BAFF/BlyS) as an Immunological Marker for Lympho proliferative Disorders Associated with Chronic Hepatitis C2008

    • Author(s)
      Uchikoshi M, Ito T, Shimozuma Y, Inokuchi T, Morikawa K, Nozawa H, Shimazaki T and M. Imawari
    • Organizer
      59th Annual Meeting of the American Association for the Study of Liver Disease
    • Place of Presentation
      San Francisco
    • Data Source
      KAKENHI-PROJECT-18590749
  • [Presentation] HCV関連リンパ増殖性疾患における血清B細胞増殖因子(BAFF/BLyS)2008

    • Author(s)
      打越学, 伊藤敬義, 井口桃子, 森川賢一, 下間祐, 井廻道夫
    • Organizer
      第94回日本消化器病学会総会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-18590749
  • [Presentation] C型慢性肝炎患者におけるB細胞HCV感染とHCV関連リンパ増殖性疾患マーカーに対する抗ウイルス療法の効果2007

    • Author(s)
      井口桃子、伊藤敬義、打越学、野沢妃佐子、島崎とも江、井廻道夫
    • Organizer
      第43回日本肝臓学会総会、ワークショップ1「肝炎ウイルス研究の進歩」
    • Place of Presentation
      ホテルグランパシフィックメリディアン
    • Data Source
      KAKENHI-PROJECT-18590749
  • [Presentation] C型慢性肝炎患者におけるB細胞HCV感染と免疫グロブリン超可変領域遺伝子clonality発症の解析2007

    • Author(s)
      井口桃子、伊藤敬義、打越学、森川賢一、野沢妃佐子、島崎とも江、井廻道夫
    • Organizer
      第47回京都肝セルバイオロジー研究会
    • Place of Presentation
      ホテルオークラ京都
    • Year and Date
      2007-07-14
    • Data Source
      KAKENHI-PROJECT-18590749
  • [Presentation] C型慢性肝炎患者におけるリンパ球系細胞へのHCV感染及びその病態に及ぼす影響とIFN療法への反応性2006

    • Author(s)
      伊藤敬義, 井口桃子, 打越学, 野沢妃佐子, 島崎とも江, 井廻道夫
    • Organizer
      第42回日本肝臓学会総会、シンポジウム1「難治性ウイルス肝炎に対する新しい治療の基礎的臨床的検討」
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-18590749
  • [Presentation] C型肝炎ウィルス感染者におけるB細胞へのHCV感染とHCV関連clonalityの検討2006

    • Author(s)
      井口桃子, 伊藤敬義, 打越学, 野沢妃佐子, 島崎とも江, 井廻道夫
    • Organizer
      第42回日本肝臓学会総会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-18590749
  • 1.  MORIYAMA Takashi (10240706)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 0 results
  • 2.  KANEKO Takashi (10254913)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 3.  NAKAMURA Ikuo (40251243)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 4.  ITO Takayoshi (50317517)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 21 results
  • 5.  安藤 量基 (20265276)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  HIROISHI Kazumasa (80296996)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  ITAI Yuji (30010268)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  YOSHIKAWA Kohki (40114714)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  WATANABE Tokuko (40092382)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  SHIGA Junji (10110694)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  IIO Masahiro (80143486)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  大西 真 (00183236)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  GUNJI Toshiaki
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  NAKAGAMA Hitoshi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  中釜 斉
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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