HIRAI Keiji 平井恵二

Researcher Number	70156628
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2007: Tokyo Medical and Dental University, 難治疾患研究所, 准教授 2004 – 2006: 東京医科歯科大学, 難治疾患研究所, 助教授 1991 – 2002: 東京医科歯科大学, 難治疾患研究所, 助教授 1991: 東京医科歯科大学, 難治疾患研究所・自律生理部門, 助教授 1991: Tokyo Medcial and Dental University, Medical Research Institute, Dept. of Autono, 難活疾患研究所・自律生理部門, 助教授 … More 1990: 東京医科歯科大学難治疾患研究所, 自律生理部門, 助手 1989: 東京医科歯科大学, 難治疾患研究所・自律生理部門, 助手 1988 – 1989: 東京医科歯科大学, 難治疾患研究所, 助手 Less
Review Section/Research Field	Principal Investigator Ophthalmology Except Principal Investigator Neuroscience in general / 睡眠学 / Ophthalmology / 睡眠学 / General physiology / 計測・制御工学
Keywords	Principal Investigator Nucleotide receptor / Fura-2 / fura-2 / Inositol triphosphate / Uridine triphosphate / Adenosine triphosphate / Calcium homeostasis / Intracellular calcium concentration / Suprachoroid / カルシウムイオン … More / furaー2 / 細胞内情報伝達系 / ATP / 細胞内カルシウム濃度 / nucleotide receptor / イノシトール三燐酸(IP3) / ウリジン三燐酸(UTP) / アデノシン三燐酸(ATP) / カルシウムホメオスタシス / 細胞内カルシウムイオン動態 / 脈絡上板 / Ca依存性Kチャネル / 電位依存性Caチャネル / 膜電位固定法 / 細胞内電位記録 / シナプス後電位 / 細胞内Caイオン濃度 / マイスナ-神経叢細胞 … More Except Principal Investigator 成長円錐 / 腸神経系 / モチリン / オレキシン / VIP / Motilin / Ghrelin / グレリン / REM sleep / 睡眠 / 脳 / ナルコレプシー / レム睡眠 / ノンレム睡眠 / Mechanosensitivity / 神経成長円錐 / カルシウムチャネル / 近接場光学顕微鏡 / 機械受容性 / 微分干渉顕微鏡 / 光学技術 / 光ピンセット / シナプス / Growth cone / Synaptic transmission / Enteric nervous system / Distributed control system / カルシウム / 神経伝達 / ニューラルネット / シナプス伝達 / 分散制御システム / 成長錐 / 神経活性物質 / 生理活性物質 / 感覚ニューロン / 一次求心路 / Ca^<2+>-uptake / Gap junction / Fura-2 / Interfibroblastic space / Suprachoroid / Choroidal fibroblast / Choroidal melanocyte / dye-couplingの動的観察 / 膜電位 / 細胞外線維 / 細胞内カルシウムイオン / ionーcoupling / 微粒子炭素懸濁液 / uveoscleral outflow / ギャップ結合 / カルシウム取り込み機構 / furaー2 / ATP / 電顕的形態 / Furaー2 / 免疫電顕法 / カルシウムイオン取り込み機構 / gap junction / 細胞内カルシウムイオン濃度 / intertibroblastic Space / 脈絡膜上板 / 脈絡膜線維芽細胞 / 脈絡膜メラニン細胞 / Parkinson's Disease / Orexin / Food intake / Non-REM sleep / Sleep disorder / ドーパミン / ドパミン / パーキンソン病 / オレキシ / 摂食 / 睡眠障害 / Electrophysiology / Neuropeptide Y / Orexins / Enteric Nervous System / Gut Functions / Sleep-Wake / 電気生理学 / ニューロペプチドY / 腸管機能 / 睡眠・覚醒 / histamine / narcolepsy / wakefulness / non-REM sleep / orexin / 脳波 / モルモット / ラット / 睡眠覚醒調節 / ヒスタミン / 覚醒 / fluorescence staining / cell adhesion / growth cones / cultured neurons / cooled CCD camera / evanescent light field / total internal reflection fluorescence microscopy / laser light beam / 蛍光標識 / 落射蛍光顕微鏡 / レーザー・ビーム / 脊髄後根神経節細胞 / 接着 / 免疫染色法 / 三叉神経節細胞 / 脊髄後根神経節 / 近接陽光 / 蛍光標識法 / 細胞接着 / 培養細胞 / 冷却CCDカメラ / 近接場光 / 光全反射 / レーザー光線 / Transmitter release / Adhesivity / Galvanotropism / Calcium concentration / Calcium channel / Chloride channel / Nerve growth cone / 走査型電子顕微鏡 / 免疫学的方法 / コリンエステラーゼ / 伝達物質放出 / 接着性 / 電場感受性 / 細胞内カルシウム / クロライドチャネル / Electric field / Ion channel / Optical technology / Neurotransmitter / Synapse / Neuron / ホールセルパッチクランプ / 神経成長因子 / 神経伝達物質 / 電場 / イオンチャネル / 先端的光学技術 / 伝達物質 / 神経細胞 / membrane protein molecule / gold particle / video-image processing / DIC-microscope / optical technology / nano-meter measuring / laser beam / optical tweezers / 神経生理学 / ナノメートル計測 / 膜蛋白分子 / 金コロイド粒子 / ビデオ画像処理 / ナノ・メートル計測 / レーザー光 / Membrane pump / Transmembrane signal transduction / Neural network / Neurons / Autonomic nervous system / 分散型制御システム / 神経回路 / シナプス形成 / ナトリウムポンプ / 分散型制御 / ポンプ機能 / 細胞内情報伝達 / ニューロン / 自律神経系 / Neural net / Neuroactive substances / Submucous plexus / Myenteric plexus / GTP結合蛋白 / マイスナー神経叢 / アウェルバッハ神経叢 / 粘膜下神経叢 / 筋層間神経叢 / 神経細胞培養 / C-AMP / 節状神経節 / 後根神経節 / 化学受容性 / 機能構築 / サブスタンスP / カルシウム依存性カリウム・チャネル Less

Studies of neurophysiological regulation of sleep-wake states using animal models for sleep research
- Principal Investigator
  
  HONDA Kazuki
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  睡眠学
- Research Institution
  Tokyo Medical and Dental University
Sleep and Gut Functions : Electrophysiological Actions of Sleep-Related Peptides in the Enteric Nervous System
- Principal Investigator
  
  KATAYAMA Yoshifumi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  睡眠学
- Research Institution
  Tokyo Medical and Dental University
Role of orexin in the regulation of sleep-wakefulness in rats
- Principal Investigator
  
  HONDA Kazuki
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  睡眠学
- Research Institution
  Tokyo Medical and Dental University
TRIAL FOR A MULTI-MODE MICROSCOPE WITH EVANECSENT OPTICS
- Principal Investigator
  
  KATAYAMA Yoshifumi
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General physiology
- Research Institution
  TOKYO MEDICAL AND DENTAL UNIVERSITY
Dynamics of Nerve Growth Cone Guidance and Adhesion
- Principal Investigator
  
  KATAYAMA Yoshifumi
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (A).
- Research Field
  
  Neuroscience in general
- Research Institution
  Tokyo Medical and Dental University
Mobility of neuronal growth-cones and formation of synapses
- Principal Investigator
  
  KATAYAMA Yoshifumi
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Field
  
  Neuroscience in general
- Research Institution
  Tokyo Medical and Dental University
Ultramicromanipulation system with laser optical tweezer
- Principal Investigator
  
  KATAYAMA Yoshifumi
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Neuroscience in general
- Research Institution
  Tokyo Medical and Dental University
一次求心性ニューロンの電気生理学的特性と化学受容性:一次求心路の機能構築との関連
- Principal Investigator
  
  片山芳文
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokyo Medical and Dental University
一次求心系ニューロンの電気生理学的特性と化学受容性:一次求心路の機能構築とその関連
- Principal Investigator
  
  KATAYAMA Yoshifumi
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokyo Medical and Dental University
Autonomous Distributed Control Systems in the Enteric Nervous System
- Principal Investigator
  
  KATAYAMA Yoshifumi
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Tokyo Medical and Dental University
Autonomous ditributed control system in the autonomic nervous system : Physiological and bio-engineering approaches
- Principal Investigator
  
  KATAYAMA Yoshifumi
- Project Period (FY)
  1992 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  計測・制御工学
- Research Institution
  Tokyo Medical and Dental University
Investigations on physiological functions of rabbit eye suprachoroid.Principal Investigator
- Principal Investigator
  
  HIRAI Keiji
- Project Period (FY)
  1991 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Ophthalmology
- Research Institution
  Tokyo Medical and Dental University
細胞応答発現時の細胞内カルシウムイオン動態とそのセカンドメッセンジャ-機能の解析Principal Investigator
- Principal Investigator
  
  平井恵二
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokyo Medical and Dental University
A Morphological and Functional Study of Choroidal Melanocytes
- Principal Investigator
  
  TOKORO Takashi
- Project Period (FY)
  1988 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  Ophthalmology
- Research Institution
  Tokyo Medical and Dental University

All 2007 2006 2005

All Journal Article Presentation

[Journal Article] A histamine. synthesis inhibitor, alpha-fluoromethyl histidine, inhibits orexin-induced wakefulness in rats2007
- Author(s)
  Honda K, Seki Y, Kotani M, Akanmu MA, Hirai K, Katayama Y, Yanai K
- Journal Title
  
  J Sleep Res 15(supple 1)
  
  Pages: 140-141
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18603002
[Journal Article] Action of PACAP on submucosal neurons of guinea-pig caecum.2006
- Author(s)
  Okada, Y., Aikawa, Y., Hirai, K., Katayama, Y.
- Journal Title
  
  J. Physiol. Sci. 56
- NAID
  130005448473
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17605004
[Journal Article] A histamine synthesis inhibitor, alpha-fluoomethylhistidine, inhibits orexin-induced wakefulness in rats.2006
- Author(s)
  Honda K, Seki Y, Kotani M, Akanmu MA, Hirai K, Katayama Y, Yanai K
- Journal Title
  
  J.Sleep Research 15
  
  Pages: 140-141
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17605004
[Journal Article] Action of PACAP on submucosal neurons of guinea-pig caecum.2006
- Author(s)
  Okada Y, Aikawa Y, Hirai K, Katayama Y
- Journal Title
  
  J.Physiol.Science 56
- NAID
  130005448473
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17605004
[Journal Article] A histamine synthesis inhibitor, alpha-fluoromethyl histidine, inhibit s orexin-induced wakefulness in rats2006
- Author(s)
  Honda K, Seki Y, Kotani M, Akanmu MA, Hirai K, Katayama Y, Yanai K.
- Journal Title
  
  J Sleep Res 15(Supple1)
  
  Pages: 140-141
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18603002
[Journal Article] Action of PACAP on submucosal neurons of guinea-pig caecum.2006
- Author(s)
  Okada Y, Aikawa Y, Hirai K, Katayama Y
- Journal Title
  
  J. Physiol. Sci. 56(Supple)
- NAID
  130005448473
- Data Source
  KAKENHI-PROJECT-17605004
[Journal Article] A new cytochemical method for in situ detection of cholinergic synaptic transmission by staining of Cu^<2+> incorporated in frog neuromuscular junction during nerve stimulation.2006
- Author(s)
  Hirai, K., Tanaka, E., Motlica-Heino, I., Katayama, Y., Higashi, H., Tsuji S.
- Journal Title
  
  Biomedical Research 27
  
  Pages: 125-130
- NAID
  130004470658
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17605004
[Journal Article] A histamine synthesis inhibitor, alpha-fluormethylhistidibe, inhibits orexin-induced wakefulness in rats.2006
- Author(s)
  Honda, K., Seki, Y., Kotani, M., Akanmun, M.A., Hirai, K., Katayama, Y., Yanai, K.
- Journal Title
  
  J. Sleep Research 15
  
  Pages: 140-141
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17605004
[Journal Article] A histamine synthesis inhibitor, alpha-fluoromethy1 histidine, inhibits orexin-induced wakefulness in rats2006
- Author(s)
  Honda K, Seki Y, Kotani M, Akanmu MA, Hirai K, Katayama Y, Yanai K.
- Journal Title
  
  J Sleep Res 15(Supple.1)
  
  Pages: 140-141
- Data Source
  KAKENHI-PROJECT-18603002
[Journal Article] A new cytochemical method for in situ detection of cholinergic synaptic transmission by staining of Cu^<2+> incorporated in frog neuromuscular junction during nerve stimulation.2006
- Author(s)
  Hirai K, Tanaka E, Motelica-Heino I, Katayama Y, Higashi H, Tsuji S
- Journal Title
  
  Biomedical Research 27
  
  Pages: 125-130
- NAID
  130004470658
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17605004
[Journal Article] A new cytochemical method for in situ detection of cholinergic synaptic transmission by staining^<2+> incorporated in frog neuromuscular junction during nerve stimulation.2006
- Author(s)
  Hirai K, Tanaka E, Motelica-Heino I, Katayama Y, Higashi H, Tsuji S
- Journal Title
  
  Biomedical Journal 27
  
  Pages: 125-130
- Data Source
  KAKENHI-PROJECT-17605004
[Journal Article] Actions of ghrelin and motilin in the myenteric plexus of the guinea-pig small intestine.2005
- Author(s)
  Katayama, Y., Okada, Y., Hirai, K., Honda, K.
- Journal Title
  
  Autonomic Neuroscience; Basic ＆ Clinical 119
  
  Pages: 148-148
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17605004
[Journal Article] Actions of ghrelin and motilin in the myenteric plexus of the guinea-pig small intestine.2005
- Author(s)
  Katayama Y, Okada Y, Hirai K, Honda K
- Journal Title
  
  Autonomic Neuroscience : Basic and Clinical 119
  
  Pages: 148-148
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17605004
[Journal Article] Action of orexins on individual myenteric neurons of the gunea-pig ileum : orexin A or B?2005
- Author(s)
  Katayama Y, Hirai K, Homma T, Noda Y, Honda K.
- Journal Title
  
  NeuroReport 16
  
  Pages: 745-749
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16614003
[Journal Article] Action of orexins on individual myenteric neurons of the gunea-pig ileum : orexin A or B?2005
- Author(s)
  Katayama Y, Hirai K, Homma T, Noda Y, Honda K
- Journal Title
  
  NeuroReport 16
  
  Pages: 745-749
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16614003
[Journal Article] Motilin inhibits ganglionic transmission in the myenteric plexus of the guinea-pig ileum.2005
- Author(s)
  Katayama, Y., Noda, Y., Hirai, K., Honda, K.
- Journal Title
  
  Neuroscience Research 53
  
  Pages: 156-160
- NAID
  10017130222
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17605004
[Journal Article] Excitatory actions of motilin on myenteric neurons of the guinea-pig small intestine.2005
- Author(s)
  Katayama Y., Ooishi K, Hirai K, Homma T, Noda Y
- Journal Title
  
  Autonomic Neuroscience : Basic and Clinical 118
  
  Pages: 88-92
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17605004
[Journal Article] Actions of orexins on individual myenteric neurons of the guinea-pig ileum : orexin A or B?2005
- Author(s)
  Katayama, Y., Hirai, K., Homma, T., Noda, Y., Honda, K.
- Journal Title
  
  NeuroReport 16
  
  Pages: 745-749
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17605004
[Journal Article] Motilin inhibits ganglionic transmission in the myenteric plexus of the guinea-pig ileum.2005
- Author(s)
  Katayama Y, Noda Y, Hirai K, Honda K
- Journal Title
  
  Neuroscience Research 53
  
  Pages: 156-160
- NAID
  10017130222
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17605004
[Journal Article] Actions of orexins on individual myenteric neurons of the guinea-pig ileum : orexin A or B?2005
- Author(s)
  Katayama Y, Hirai K, Homma T, Noda Y, Honda K
- Journal Title
  
  NeuroReport 16
  
  Pages: 745-749
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17605004
[Journal Article] Excitatory actions of motilin on myenteric neurons of the guinea-pig small intestine.2005
- Author(s)
  Katayama, Y., Ooishi, K., Hirai, K., Homma, T., Noda, Y.
- Journal Title
  
  Autonomic Neuroscience : Basic and Clinical 118
  
  Pages: 88-92
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17605004
[Journal Article] Action of orexins on individual myenteric neurons of the gunea-pigileum : orexin A or B?2005
- Author(s)
  Katayama Y, Hirai K, Homma T, Noda Y, Honda K
- Journal Title
  
  NeuroReport 16
  
  Pages: 745-749
- Data Source
  KAKENHI-PROJECT-16614003
[Presentation] A histamine synthesis inhibitor, alpha-fluoromethyl histidine, inhibits orexin-induced wakefulness in rats2006
- Author(s)
  Honda K, Seki Y, Kotani M, Akanmu MA, Hirai K, Katayama Y, Yanai K.
- Organizer
  18th Cong Eur Sleep Res Soc
- Place of Presentation
  Innsubruck
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18603002

1. KATAYAMA Yoshifumi (20014144)

# of Collaborated Projects: 13 results

# of Collaborated Products: 23 results
2. TATSUMI Hitoshi (20171720)

# of Collaborated Projects: 7 results

# of Collaborated Products: 0 results
3. FURUKAWA Tetsushi (80251552)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
4. HONDA Kazuki (70173656)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. FUNATA Midori (10143554)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. TOKORO Takashi (20013865)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. MIHARA Satoshi (40166103)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. 森田喜一郎 (20140642)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. TSUJI S.

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. MCCAIG C.D.

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. HOMMA Tommo (80242246)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. IWASAKI Yasuhiko (90280990)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. AKAZAWA Yoshihiko (70159317)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 西彰五郎 (00080557)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 長谷川豊 (10198731)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 窪田美幸 (50195509)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 鎌田光二 (50137048)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. MARTIN I.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. NORTH R.A.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. LEES G.M.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. MCCAING C.D.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. NISHI S.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. MIHARA S.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. HIRAI K.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. TATSUMI H.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. NORTH R A

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. TSUJI Shigeru

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. MCCAIG C. D.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 本田和樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 15 results

HIRAI Keiji 平井 恵二

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Investigations on physiological functions of rabbit eye suprachoroid.Principal Investigator

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細胞応答発現時の細胞内カルシウムイオン動態とそのセカンドメッセンジャ-機能の解析Principal Investigator

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[Journal Article] A histamine. synthesis inhibitor, alpha-fluoromethyl histidine, inhibits orexin-induced wakefulness in rats2007

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[Journal Article] Action of PACAP on submucosal neurons of guinea-pig caecum.2006

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HIRAI Keiji 平井恵二