Wada Hideho 和田秀穂

… Alternative Names

WADA Hideho 和田秀穂

和田秀穂ワダヒデホ

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Researcher Number	70191830
Other IDs
External Links
Affiliation (Current)	2025: 川崎医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2010: 川崎医科大学, 医学部, 教授 2004: 川崎医科大学, 医学部・血液内科学, 助教授 2002 – 2004: 川崎医科大学, 医学部(血液内科学), 助教授 2002: 川崎医科大学, 医学部, 助教授 1994 – 2002: 川崎医科大学, 医学部, 講師 1992: 川崎医科大学, 医学部, 助手 1987: 川崎医科大学, 医学部・内科学教室, 助手
Review Section/Research Field	Principal Investigator Hematology Except Principal Investigator Hematology / Pathological medical chemistry / Experimental pathology / Human pathology
Keywords	Principal Investigator band3 / 5'-CpG-3' sites / Epo / UT-7 / β-spectrin / protein 4.2 / red cell membrane / promoter / DNA methylation / 5'-CpG-3'sites … More / protein4.2 / methylation / β-sectrin / DNA meth lation / band 3 / 分子細胞生物遺伝学 / ヒト赤芽球 / 赤血球膜蛋白 … More Except Principal Investigator 遺伝性球状赤血球症 / Band 3 / Hereditary spherocytosis / Spectrin / 遺伝子解析 / 赤血球膜 / Gene analysis / Red cell membrane / Band3 / Gene methylation / 分子電顕学 / Protein 4.2 / band3 / スペクトリン / 細胞骨格 / 赤血球膜異常症 / アンキリン / Morphogenesis / 遺伝性楕円赤血球症 / protein 4.2 / Gene expression / gene methylation / 遺伝子発現 / Molecular electron microscopy / Protein4.2 / Cytoskeleton / 形態形成 / 電顕学的検索 / spectrin / 溶血性貧血 / Red cell membrane disorders / プロテイン4.2 / 遺伝子のメチル化 / 遺伝子発現調節 / 赤血球膜蛋白質 / methylation / 5'-CpG-3' sites / Protein expression / Red cell membrane protein / Band 3 gene / Erythroblast / Protein 4.2 deficiency / Isoform / Protein 4.2 gene / Ankyrin / molecular electron microscopy / 遺伝子制御 / 膜超微構造 / 遺伝子メチル化 / 分子電顕 / CpG site / Hereditary elliptocytosis / Red cell membrane proteins / β-spectrin / band 3 / 免疫電顕 / Band4.2 / Band 4.2 / スペクトリン遺伝性楕円赤血球症 / 膜蛋白分画4.2 / 赤血球膜異常 / Control of gene expression / Hemolytic anemia / Molecular electron microsopy / Control of nege expression / red cell membrane proteins / 赤芽球分化 / 遺伝子の発現調節 / 膜蛋白質 / プロテイン分画4.2 / バンド3 / b-spectrin / gene expression / red cell membrane abnormality / red cell membrane / bisulfite method / protein 4.2 gene / AE1 gene / β-spectrin gene / promoter / 5'-CpG-3'sites / メチル化 / 膜蛋白発現調節異常 / 先天性膜蛋白異常症 / protein4.2 / 遺伝性メチル化 / 遺伝子球状赤血球症 / Cytoskeletal network / Allele 4.1 (-) Madrid / allele 4.1(-)Madrid / allele4.1(-)Madrid / Band 4.1 / Band4.1 / Liver / Spleen / Erythropoetin / Liposome / Erythropoiesis / Macrophage / 造血微小環境 / C-kit ligand / エリスロポエチン / 造血環境 / マウス / 肝臓 / 脾臓 / RT-PCR / サイトカイン / リポソーム / 赤芽球造血 / マクロファージ / Electron microscopy / Membrane rheology / Microelectrongraphy / Gene mutation / 膜物性 / Electronmicroscopy / band 4.2 / Electron micrography / Membrane proteins / 構造蛋白 / 細胞骨格蛋白 / リアルタイムRT-PCR / 血管内皮細胞 / レセプター / 免疫組織化学 / 細胞運動 / シグナリング / スフィンゴシン-1-リン酸 / 成人T細胞白血病リンパ腫 / 病理学 / protein phophatase 2A / Akt / FTY720 / マントル細胞リンパ腫 / 細胞遊走 / sphingosine-1-phosphate receptor / 血液 / 膜間粒子 / band4.2 Less

Expression of sphingosine-1-phosphate receptors in mantle cell lymphoma and its practical application
- Principal Investigator
  
  SADAHIRA Yoshito
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Kawasaki Medical School
Mechanism of Genetic and Phenotypic Expression in Hereditary Red Cell Membrane Disorders
- Principal Investigator
  
  YAWATA Yoshihito
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Kawasaki College of Allied Health Professions
Genotypic and Phenotypic Expressions in Red Cell Membrane Disorders
- Principal Investigator
  
  YAWATA Yoshihito
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Kawasaki College of Allied Health Professions
  Kawasaki Medical School
The state of DNA methylation in the promoter regions of the human red cell membrane protein genesPrincipal Investigator
- Principal Investigator
  
  WADA Hideho
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Kawasaki Medical School
Gene expression mechanism in normal and red cell membrane disorders
- Principal Investigator
  
  YAMADA Osamu, 神崎暁郎
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  KAWASAKI MEDICAL SCHOOL
A control mechanism of gene expression in red cell membranes
- Principal Investigator
  
  YAWATA Yoshihito
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Hematology
- Research Institution
  KAWASAKI MEDICAL SCHOOL
A Control Mechanism of Gene and Protein Expression in Normal and Abnormal Red Cell Membranes
- Principal Investigator
  
  YAWATA Yoshihito
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Field
  
  Hematology
- Research Institution
  KAWASAKI MEDICAL SCHOOL
Genotypic and phenotypic expressions of hereditary red cell membrane disorders
- Principal Investigator
  
  YAWATA Yoshihito
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Kawasaki Medical School
Study on gene expression control and pathophysiological mechanism of red cell membrane protein 4.2 in normal and disorders of hereditary hemolytic anemia
- Principal Investigator
  
  KANZAKI Akio
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  KAWASAKI MEDICAL SCHOOL
Molecular Genetics of Hereditary Red Cell Membrane Disorders
- Principal Investigator
  
  YAWATA Yoshihito
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  KAWASAKI MEDICAL SCHOOL
ヒト赤芽球を用いた細胞膜蛋白の発現と分化に関する分子細胞生物遺伝学的研究Principal Investigator
- Principal Investigator
  
  和田秀穂
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Hematology
- Research Institution
  Kawasaki Medical School
Cellular biochemistry and electron microscopy in hereditary red cell membrane disorders
- Principal Investigator
  
  YAWATA Yoshihito
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  KAWASAKI MEDICAL SCHOOL
Molecular biochemistry and electron microscopy in normal and abnormal human red cell membrane protein 4.2
- Principal Investigator
  
  KANZAKI Akio
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  KAWASAKI MEDICAL SCHOOL
Functional significance of erythroblastic island composed of a central macrophage and surrounding erythroblasts.
- Principal Investigator
  
  SADAHIRA Yoshito
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  KAWASAKI MEDICAL SCHOOL
分子病態から見たわが国の赤血球膜異常症の研究
- Principal Investigator
  
  八幡義人
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Kawasaki Medical School
Molecular Genetics of Hereditary Red Cell Membrane Disorders
- Principal Investigator
  
  YAWAYA Yoshihito
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Kawasaki Medical School
細胞骨格から見た赤血球膜異常症の病因・病態に関する分子生物学的研究
- Principal Investigator
  
  YAWAYA Yoshihito
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Kawasaki Medical School
Studies on molecular abnormalities of spectrin and cytoskeleton in red cell membrane disorders
- Principal Investigator
  
  YAWATA Yoshihito
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Kawasaki Medical School

All 2009 2005 2004 2002

All Journal Article Presentation

[Journal Article] DNA methylation in promoter regions of red cell membrane protein genes.2005
- Author(s)
  Remus, R., Kanzaki, A., Yawata, A., Nakanishi, H., Wada, H., Sugihara, T., Zeschnigk, M., Zuther, I., Schmitz, B., Naumann, F., Doerfler, W., Yawata, Y.
- Journal Title
  
  Int J Hematol (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370311
[Journal Article] A novel combined anomaly of glycophorin A and band 3 : Decreased glycosylation, impaired anion transport, markedly disrupted skeletal network with decreased deformability, a Tn syndrome, and uncompensated hereditary stomatocytosis with normal band 3 gene and mutated (L75I) glycophorin A gene.2005
- Author(s)
  Wada H, Kanzaki A, Yawata A, Fujimura K, Senoo T, Takahashi J, Uchikawa M, Yawata Y
- Journal Title
  
  (発表予定)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370311
[Journal Article] Relations between DNA methylation and expression in erythrocyte membrane protein (band 3, protein 4.2 and β-spectrin) genes during human erythroid development and differentiation.2005
- Author(s)
  Remus, R., Kanzaki, A., Yawata, A., Wada, H., Nakanishi, H., Sugihara, T., Zeschnigk, M., Zuther, I., Schmitz, B., Doerfler, W., Yawata, Y.
- Journal Title
  
  Int J Hematol (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370311
[Journal Article] Relations between DNA methylation and expression in erythrocyte membrane protein (band 3, protein 4.2 and β-spectrin) genes during human erythroid development and differentiation.2005
- Author(s)
  Remus, R., Kanzaki, A., Yawata, A., Wada, H., Nakanishi, H., Sugihara, T., Zeschnigk, M., Zuther, I., Schmitz, B., Doerfier, W., Yawata, Y.
- Journal Title
  
  Int J Hematol (in press)
- Data Source
  KAKENHI-PROJECT-14370311
[Journal Article] A novel combined anomaly of glycophorin A and band 3 : Decreased glycosylation, impaired anion transport, markedly disrupted skeletal network with decreased deformability, a Tn syndrome, and uncompensated hereditary stomatocytosis with normal band 3 gene and mutated (L75I) glycophorin A gene.2005
- Author(s)
  Wada H, Kanzaki A, Yawata A, Fujimura K, Senoo T, Takahashi J, Uchikawa M, Yawata Y
- Journal Title
  
  (In Preparation)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370311
[Journal Article] 「研究成果報告書概要(欧文)」より2005
- Author(s)
  Remus, R., Kanzaki, A., Yawata, A., Wada, H., Nakanishi, H., Sugihara, T., Zeschnigk, M., Zuther, I., Schmitz, B., Doerfler, W., Yawata, Y.
- Journal Title
  
  Int J Hematol (in press)
- Data Source
  KAKENHI-PROJECT-14370311
[Journal Article] A novel combined anomaly of glycophorin A and band 3 : Decreased glycosylation, impaired anion transport, markedly disrupted skeletal network with decreased deformability, a Tn syndrome, and uncompensated hereditary stomatocytosis with normal band 3 gene and mutated (L751) glycophorin A gene.2005
- Author(s)
  Wada, H., Kanzaki, A., Yawata, A., Fujimura, K., Senoo, T., Takahashi., Uchikawa, M., Yawata, Y.
- Journal Title
  
  (発表予定)
- Data Source
  KAKENHI-PROJECT-14370311
[Journal Article] DNA methylation in promoter regions of red cell membrane protein genes in normal individuals and hereditary membrane disorders.2005
- Author(s)
  Remus, R., Kanzaki, A., Yawata, A., Nakanishi, H., Wada, H., Sugihara, T., Zeschnigk, M., Zuther, I., Schmitz, B., Naumann, F., Doerfler, W., Yawata, Y.
- Journal Title
  
  Int J Hematol (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370311
[Journal Article] Monocyte/macrophage-specific marker CD163+ histiocytic sarcoma : Case report with clinical, morphologic, immunohistochemical, and molecular genetic studies.2004
- Author(s)
  Mikami, M., Sadahira, Y., Suetsugu, Y., Wada, H., Sugihara, T.
- Journal Title
  
  Int J Hematol 80
  
  Pages: 365-369
- NAID
  10014023092
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370311
[Journal Article] Multiple myeloma complicated by autoimmune hemolytic anemia.2004
- Author(s)
  Wada, H., Yata, K., Mikami, M., Suemori, S., Nakanishi, H., Kondo, T., Tsujioka, T., Suetsugu, Y., Otsuki, T., Sadahira, Y., Yawata, Y., Sugihara, T.
- Journal Title
  
  Int Med 43(7)
  
  Pages: 595-598
- NAID
  130000084921
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370311
[Journal Article] Multiple myeloma complicated by autoimmune hemolytic anemia.2004
- Author(s)
  Wada, H., Yata, K., Mikami, M., Suemori, S., Nakanishi, H., Kondo, T., Tsujioka, T., Suetsugu, Y., Otsuki, T., Sadahira, Y., Yawata, Y., Sugihara, T.
- Journal Title
  
  Int Med 43
  
  Pages: 595-598
- NAID
  130000084921
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370311
[Journal Article] Interleukin 10 abolishes the growth inhibitory effects of alltrans retinoic acid on human myeloma cells.2002
- Author(s)
  Otsuki T, Yata K, Sakaguchi H, Kurebayashi J, Matsuo Y, Uno M, Fujii T, Eda S, Isozaki Y, Yawata Y, Yamada O, Wada H, Sugihara T, Ueki A
- Journal Title
  
  Br J Haematol 116
  
  Pages: 787-795
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370311
[Journal Article] Interleukin 10 abolishes the growth inhibitory effects of alltrans retinoic acid on human myeloma cells.2002
- Author(s)
  Otsuki T, Yata K, Sakaguchi H, Kurebayashi J, Matsuo Y, Uno M, Fujii T, Eda S, Isozaki Y, Yawata Y, Yamada O, Wada H, Sugihara T, Ueki A
- Journal Title
  
  Br J Haematol 116(4)
  
  Pages: 787-795
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370311
[Journal Article] Synergistic growth inhibition of YM 529 with biologic response modifiers (BRMs) in myeloma cells.2002
- Author(s)
  Yata K, Otsuki T, Yamada O, Wada H, Yawata Y, Sugihara T
- Journal Title
  
  Int J Hematol 75(5)
  
  Pages: 534-539
- NAID
  10008549463
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370311
[Journal Article] Synergistic growth inhibition of YM 529 with biologic response modifiers (BRMs) in myeloma cells.2002
- Author(s)
  Yata K, Otsuki T, Yamada O, Wada H, Yawata Y, Sugihara T
- Journal Title
  
  Int J Hematol 75
  
  Pages: 534-539
- NAID
  10008549463
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370311
[Presentation] 悪性リンパ腫におけるスフィンゴシン-1-リン酸レセプターの発現2009
- Author(s)
  定平吉都,西村広健,土山準二郎,和田秀穂,杉原尚
- Organizer
  第71回日本血液学会学術集会
- Place of Presentation
  京都
- Year and Date
  2009-10-23
- Data Source
  KAKENHI-PROJECT-20590357
[Presentation] 悪性リンパ腫におけるスフィンゴシン-1-リン酸レセプターの発現2009
- Author(s)
  定平吉都, 西村広健, 土山準二郎, 和田秀穂, 杉原尚
- Organizer
  第71回日本血液学会学術集会
- Place of Presentation
  京都国際会議場
- Year and Date
  2009-10-23
- Data Source
  KAKENHI-PROJECT-20590357

1. YAWAYA Yoshihito (70069011)

# of Collaborated Projects: 15 results

# of Collaborated Products: 14 results
2. YAMADA Osamu (50104790)

# of Collaborated Projects: 14 results

# of Collaborated Products: 0 results
3. KANZAKI Akio (40148698)

# of Collaborated Projects: 12 results

# of Collaborated Products: 0 results
4. SUGIHARA Takashi (60140505)

# of Collaborated Projects: 11 results

# of Collaborated Products: 0 results
5. INOUE Takafumi (60203238)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
6. KAKU Mayumi (20319940)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
7. SADAHIRA Yoshito (30178694)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
8. OKAMOTO Naoto (20204042)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
9. 矢田健一郎 (20299184)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
10. 阿多雄之 (50184180)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. DOERFLER Walter

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. TSUCHIYAMA Junjiro (50454806)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
13. HARANO Keiko (00069072)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. HARANO Teruo (60069028)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. YASUDA Tatsuji (30092357)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. MIKAMI Makoto (90309550)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. SUETSUGU Keisyu (60309549)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. FUJIWARA Yoshiro (70342293)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. HASHIMOTO Masashi (90148693)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 高橋美加 (10258212)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 白戸りさ (40187539)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. MORLE Laurette

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. ALLOISIO Nicole

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. DERAUNAY Jean

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. DELAUNAY Jea

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. ALLOISIO Nic

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. MORLE Lauret

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Wada Hideho 和田 秀穂

WADA Hideho 和田 秀穂

和田 秀穂 ワダ ヒデホ

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The state of DNA methylation in the promoter regions of the human red cell membrane protein genesPrincipal Investigator

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ヒト赤芽球を用いた細胞膜蛋白の発現と分化に関する分子細胞生物遺伝学的研究Principal Investigator

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Wada Hideho 和田秀穂

WADA Hideho 和田秀穂

和田秀穂ワダヒデホ