Goshima Fumi 五島典

… Alternative Names

GOSHIMA Fumi 五島典

五島典

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Researcher Number	70201499
Other IDs
Affiliation (based on the past Project Information) *help	2017 – 2020: 名古屋大学, 医学系研究科, 講師 2017: 名古屋大学, 大学院・医学系研究科・ウイルス学, 講師 2016: 名古屋大学, 医学系研究科, 助教 2012 – 2014: 名古屋大学, 医学(系)研究科(研究院), 助教 2013: 名古屋大学, 大学院医学系研究科, 助教 … More 2011: 名古屋大学, 医学系研究科, 助教 2010: 名古屋大学, 大学院・医学系研究科, 助教 2004 – 2005: 名古屋大学, 大学院・医学系研究科, 助手 2001: Graduate School of Medicine, Nagano University Research associate, 大学院・医学研究科, 助手 1995 – 2000: 名古屋大学, 医学部, 助手 1988: 名古屋大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Tumor therapeutics / Virology / Clinical oncology Except Principal Investigator Virology / Otorhinolaryngology / Pediatrics / Pediatrics / Virology
Keywords	Principal Investigator HSV / アンプリコン / 遠隔転移 / 遠隔転移腫瘍 / 単純ヘルペスウイルス / 腫瘍溶解療法 / 転移性腫瘍 / 乳癌 / HF10 / 抗腫瘍ウイルス … More / central nervous system / trigeminal nerve / olfactory nerve / prenylation / US2 / 中枢神経 / 中枢神経系 / 三叉神経 / 嗅神経 / プレニル化 / US2遺伝子産物 / 癌 / ウイルス / 遺伝子治療 … More Except Principal Investigator 単純ヘルペスウイルス / 抗腫瘍ウイルス / 腫瘍溶解ウイルス療法 / HHV-6 / ウイルス増殖機構 / 遺伝子機能 / 扁平上皮癌 / 抗腫瘍ウイルス療法 / 頭頸部扁平上皮癌 / 唾液腺癌細胞 / 5FU / HF10 / 単純ヘルペス・ウイルス / 腫瘍溶解ウイルス / 5-FU / 唾液腺癌 / cell proliferation / reactivation / primary infection / BrdU / 非RI / 細胞増殖反応 / 再活性化 / 初感染 / mechanism of viral replication / protein kinase / function of viral proteins / accessory gene / herpes simplex virus / アポトーシス / US3 / 非必須遺伝子 / プロテインキナーゼ / アクセサリー遺伝子 / Pathogenicity / Virus genes / Host defense system / Human cytomegalovirus / Herpes simplex virus / 病原性 / ウイルス遺伝子 / 宿主防御機構 / ヒトサイトメガロウイルス / 細胞内輸送 / ノイラミニダーゼ / 温度感受性変異株 / インフルエンザウイルス / 母子間ﾏｲｸﾛｷﾒﾘｽﾞﾑ / EBウイルス / 免疫寛容 / 母子間マイクロキメリズム / 慢性活動性EBV感染症 / 細胞療法 / 宿主因子 / 単樹ヘルペスウイルス Less

Oncolytic virotherapy for salivary carcinoma
- Principal Investigator
  
  Esaki Shinichi
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Nagoya City University
Antitumor activity of oncolytic virus for metastatic cancerPrincipal Investigator
- Principal Investigator
  
  Goshima Fumi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor therapeutics
- Research Institution
  Nagoya University
Oncolytic activity of HF10 for head and neck squamous cell carcinomas
- Principal Investigator
  
  Esaki Shinichi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Nagoya City University
HSV-1 amplicon as a novel vector for gene transfer into refractory tumorsPrincipal Investigator
- Principal Investigator
  
  GOSHIMA Fumi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Clinical oncology
- Research Institution
  Nagoya University
Cell therapy against intractable EB virus infection using immunological tolerance
- Principal Investigator
  
  KIMURA Hiroshi
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Pediatrics
- Research Institution
  Nagoya University
単純ヘルペスウイルスの増殖を制御する宿主因子の同定とその役割の解明
- Principal Investigator
  
  NISHIYAMA Yukihiro
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Virology
- Research Institution
  Nagoya University
Functional Analysis of US2 Gene Product of Herpes Simplex Virus Type 2Principal Investigator
- Principal Investigator
  
  GOSHIMA Fumi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  Nagoya University
Analysis of pathogenesis of primary infection and reactivation of HHV-6
- Principal Investigator
  
  YOSHIKAWA Tetsushi
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Nagoya University
Studies on the properties and functions of accessory gene products of herpes simplex virus
- Principal Investigator
  
  NISHIYAMA Yukihiro
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Virology
- Research Institution
  Nagoya University
Studies on the functions of herpesvirus genes involved in evading the host immune system
- Principal Investigator
  
  NISHIYAMA Yukihiro
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Virology
- Research Institution
  Nagoya University
B型インフルエンザts変異株ノイラミニダーゼの性格づけ
- Principal Investigator
  
  前野幸一郎
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  Nagoya University

All 2018 2017 2016 2014 2013 2012 2011 2010 2005 2004 Other

All Journal Article Presentation

[Journal Article] The efficacy of combination therapy with oncolytic herpes simplex virus HF10 and dacatbazine in a mouse melanoma model2017
- Author(s)
  Tanaka R,Goshima F, Esaki S, Sato Y, Murata T, Nishiyama Y, Watanabe D, Kimura H
- Journal Title
  
  Am J Cancer Res
  
  Volume: 7 Pages: 1693-1703
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07166
[Journal Article] Oncolytic viral therapy with a combination of HF10, a herpes simplex virus type 1 variant and granulocyte-macrophage colony-stimulating factor for murine ovarian cancer.2014
- Author(s)
  Goshima F, Esaki S, Luo C, Kamakura M, Kimura H, Nishiyama Y.
- Journal Title
  
  Int J Cancer.
  
  Volume: 134 Pages: 2865-2877
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24501351
[Journal Article] Oncolytic viral therapy with a combination of HF10, a herpes simplex virus type 1 variant and granulocyte-macrophage colony-stimulating factor for murine ovarian cancer2014
- Author(s)
  Goshima F1, Esaki S, Luo C, Kamakura M, Kimura H, Nishiyama Y
- Journal Title
  
  Int J Cancer
  
  Volume: 15 Issue: 12 Pages: 2865-77
- DOI
  10.1002/ijc.28631
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24501351
[Journal Article] Heat shock protein 90 inhibitors repress latent membrane protein 1 (LMP1) expression and proliferation of Epstein-Barr virus-positive natural killer cell lymphoma2013
- Author(s)
  Murata T, Iwata S, Siddiquey NA, Kanazawa T, Goshima F, Kimura H, Tsurumi T.
- Journal Title
  
  PLoS One
  
  Volume: 8 Issue: 5 Pages: e63566-e63566
- DOI
  10.1371/journal.pone.0063566
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659493
[Journal Article] Enhanced antitumoral activitiy of oncolytic herpes simplex virus with gemcitabine using colorectal tumor models.2012
- Author(s)
  Esaki S, Goshima F, Kimura H, Murakami S, Nishiyama Y.
- Journal Title
  
  International Journal of Cancer
  
  Volume: 132 Issue: 7 Pages: 1592-601
- DOI
  10.1002/ijc.27823
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24501351
[Journal Article] Herpes simplex virus induces the marked up-regulation of the zinc finger transcriptional factor INSM1, which modulates the expression and localization of the immediate early protein ICP02011
- Author(s)
  Kamakura M, Goshima F, Luo C, et al
- Journal Title
  
  Virology Journal
  
  Volume: 8 Issue: 1 Pages: 257-257
- DOI
  10.1186/1743-422x-8-257
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390088
[Journal Article] Auditory and vestibular defects induced by experimental labyrinthitis following herpes simplex virus in mice2011
- Author(s)
  Esaki S, Goshima F, Kimura H, et al
- Journal Title
  
  Acta Oto-Laryngologica
  
  Volume: 131 Issue: 7 Pages: 684-691
- DOI
  10.3109/00016489.2010.546808
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390088
[Journal Article] Apoptosis induction after herpes simplex virus infection differs according to cell type in vivo.2010
- Author(s)
  Esaki, S., Goshima, F., Katsumi, S., et.al.
- Journal Title
  
  Archieves of Virology
  
  Volume: 155 Pages: 1235-1245
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390088
[Journal Article] Intercellular trafficking activity of herpes simplex virus US11 gene product in the mouse brain.2005
- Author(s)
  Mori I, Koshizuka T, Goshima F et al.
- Journal Title
  
  Molecular Brain Research. 136
  
  Pages: 158-163
- Data Source
  KAKENHI-PROJECT-16590383
[Journal Article] Axonal injury in experimental herpes simplex encephalitis2005
- Author(s)
  Mori I, Goshima F, Mizuno T, et al.
- Journal Title
  
  Brain Reserch 1057
  
  Pages: 186-190
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590383
[Journal Article] Intercellular trafficking activity of herpes simplex virus US11 gene product in the mouse brain.2005
- Author(s)
  Mori I, Koshizuka T, Goshima F et al.
- Journal Title
  
  Molecular Brain research. 136
  
  Pages: 158-163
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590383
[Journal Article] The vomeronasal chemosensory system as a route of neuroinvasion by herpes simplex virus2005
- Author(s)
  Mori I, Goshima F, Ito H et al.
- Journal Title
  
  Virology 334
  
  Pages: 51-58
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590383
[Journal Article] Axonal injury in experimental herpes simplex encephalitis2005
- Author(s)
  Mori I, Goshima F, Mizuno T, et al.
- Journal Title
  
  Brain Research 1057
  
  Pages: 186-190
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590383
[Journal Article] HF10 an attenuated herpes simplex virus (HSV) type2 clone, lacks neuroinvasiveness and protects mice against lethal challenge with HSVtypes 1 and 22005
- Author(s)
  Mori I, Liu B, Goshima F et al.
- Journal Title
  
  Microbes and Infection 7
  
  Pages: 1492-1500
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590383
[Journal Article] HF10 an attenuated herpes simplex virus(HSV) type2 clone,lacks neuroinvasiveness and protects mice against lethal challenge with HSVtypes 1 and 22005
- Author(s)
  Mori I, Liu B, Goshima F et al.
- Journal Title
  
  Microbes and Infection 7
  
  Pages: 1492-1500
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590383
[Journal Article] HF10 an attenuated herpes simplex virus(HSV) type2 clone, lacks neuroinvasiveness and protects mice against lethal challenge with HSVtypes 1 and22005
- Author(s)
  Mori I, Liu B, Goshima F et al.
- Journal Title
  
  Microbes and Infection 7
  
  Pages: 1492-1500
- Data Source
  KAKENHI-PROJECT-16590383
[Journal Article] Intercellular trafficking activity of herpes simplex virus US11 gene product in the mouse brain2005
- Author(s)
  Mori I, Koshizuka T, Goshima F et al.
- Journal Title
  
  Molecular Brain Research 136
  
  Pages: 158-163
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590383
[Journal Article] Oncolytic viral therapy for breast cancer with herpes simplex virus type 1 mutant HF 102004
- Author(s)
  Teshigahara O, Goshima F, Takao K et al.
- Journal Title
  
  Journalof Surgical Oncology. 85
  
  Pages: 42-7
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590383
[Journal Article] Treatment of solid sarcomas in immunocompetent mice with novel, oncolytic herpes simplex viruses2004
- Author(s)
  Sugiura S, Goshima F, Takakuwa H
- Journal Title
  
  Otolaryngoly Head and Neck Surgery 130
  
  Pages: 470-478
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590383
[Journal Article] Oncolytic viral therapy for breast cancer with herpes simplex virus type 1 mutant HF 102004
- Author(s)
  Teshigahara O, Goshima F, Takao K et al.
- Journal Title
  
  Journal of Surgical Oncology 85
  
  Pages: 42-47
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590383
[Presentation] Oncolytic effect of HF10 for breast cancer lung metastasi2018
- Author(s)
  Fumi Goshima, Shinichi Esaki, Yoshitaka Sato, Takayuki Murata, Hiroshi Kimura
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K07166
[Presentation] Antitumor effect of oncolytic HSV1 HF10 for metastatic breast cancer2018
- Author(s)
  Fumi Goshima, Shinichi Esaki, Gaku Takano, Takahiro Watanabe, Yoshitaka Sato, Takayuki Murata, Hiroshi Kimura
- Organizer
  第66回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-16K07166
[Presentation] Antitumor effect of the HSV1 HF10 for metastatic cancer2017
- Author(s)
  Goshima F, Esaki S, Takano G, Sato Y, Murata T, Nishiyama Y, Kimura H
- Organizer
  第65回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-16K07166
[Presentation] Combination therapy with oncolytic HSV HF10 and dacarbazine for malignant melanoma2016
- Author(s)
  Goshima F, Esaki S, Tanaka R, Sato Y, Murata T, Watanabe D, Kimura H
- Organizer
  10th International Oncolytic Virus Meeting, Vancouver
- Place of Presentation
  Vancouver (Canada)
- Year and Date
  2016-10-01
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07166
[Presentation] In vivo study of the antitumor effect of the IL2-HSV amplicon vector2016
- Author(s)
  Goshima F, Esaki S, Tanaka R, Sato Y, Murata T, Nishiyama Y, Kimura H
- Organizer
  第64回日本ウイルス学会学術集会
- Place of Presentation
  札幌コンベンションセンター（北海道札幌市）
- Year and Date
  2016-10-23
- Data Source
  KAKENHI-PROJECT-16K07166
[Presentation] マウス卵巣癌腹腔播種モデルにおけるHSV-1 HF10とマウスGM-CSFアンプリコンを用いた抗腫瘍効果の検討2013
- Author(s)
  五島典、江崎伸一、田中るい、村田貴之、渡辺大輔、木村宏、西山幸廣
- Organizer
  第61回日本ウイルス学会学術集会
- Place of Presentation
  神戸国際会議場(神戸市）
- Data Source
  KAKENHI-PROJECT-24501351
[Presentation] マウス卵巣癌腹膜播種モデルにおけるHSV-1　HF10とマウスGM-CSFアンプリコンを用いた治療効果の検討2012
- Author(s)
  五島典、江崎伸一、武藤義文、岩田誠子、鎌倉真紀、渡辺大輔、木村宏、西山幸廣
- Organizer
  日本ウイルス学会学術集会
- Place of Presentation
  大阪（グランキューブ大阪）
- Data Source
  KAKENHI-PROJECT-24501351
[Presentation] 単純ヘルペスウイルス(HSV)感染によるINSM1の発現変化とその役割2010
- Author(s)
  鎌倉真紀、牛島洋子、五島典, 他
- Organizer
  第58回日本ウイルス学会学術集会
- Place of Presentation
  あわぎんホール(徳島)
- Year and Date
  2010-11-09
- Data Source
  KAKENHI-PROJECT-22390088
[Presentation] マウス悪性黒色腫両側皮下モデルにおけるダカルバジンの併用療法
- Author(s)
  田中るい、五島典、江崎伸一、村田貴之、渡辺大輔、西山幸廣、木村宏
- Organizer
  ウイルス学会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2014-11-10 – 2014-11-12
- Data Source
  KAKENHI-PROJECT-24501351

1. KIMURA Hiroshi (30303621)

# of Collaborated Projects: 4 results

# of Collaborated Products: 14 results
2. ESAKI Shinichi (20620983)

# of Collaborated Projects: 4 results

# of Collaborated Products: 12 results
3. NISHIYAMA Yukihiro (60115615)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. KAMAKURA Maki (80437003)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
5. ITO Yoshinori (20373491)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. TSURUMI Tatsuya (90172072)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. DAIKOKU Tohru (80291409)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. YOSHIKAWA Tetsushi (80288472)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. SUGA Sadao (70257616)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. ASANO Yoshizo (40131180)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. TAKANO Gaku (00812744)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
12. 前野幸一郎 (00022773)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 渡邉大輔 (40324404)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
14. 濱島有喜 (30343403)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Goshima Fumi 五島 典

GOSHIMA Fumi 五島 典

五島 典

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Antitumor activity of oncolytic virus for metastatic cancerPrincipal Investigator

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HSV-1 amplicon as a novel vector for gene transfer into refractory tumorsPrincipal Investigator

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Functional Analysis of US2 Gene Product of Herpes Simplex Virus Type 2Principal Investigator

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[Journal Article] The efficacy of combination therapy with oncolytic herpes simplex virus HF10 and dacatbazine in a mouse melanoma model2017

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[Journal Article] Oncolytic viral therapy with a combination of HF10, a herpes simplex virus type 1 variant and granulocyte-macrophage colony-stimulating factor for murine ovarian cancer.2014

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[Journal Article] Oncolytic viral therapy with a combination of HF10, a herpes simplex virus type 1 variant and granulocyte-macrophage colony-stimulating factor for murine ovarian cancer2014

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[Journal Article] Heat shock protein 90 inhibitors repress latent membrane protein 1 (LMP1) expression and proliferation of Epstein-Barr virus-positive natural killer cell lymphoma2013

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Goshima Fumi 五島典

GOSHIMA Fumi 五島典

五島典