Oue Shiro 大上史朗

… Alternative Names

大上史朗オオウエシロウ

OHUE Shiro 大上史朗

OHUE Shiroh 大上史朗

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Researcher Number	70213626
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2016 – 2017: 愛媛大学, 医学系研究科, 准教授 2015: 愛媛大学, 医学(系)研究科(研究院), 准教授 2015: 愛媛大学, 大学院医学系研究科, 准教授 2013: 愛媛大学, 医学部附属病院, 講師 2003 – 2004: 愛媛大学, 医学部附属病院, 講師 … More 1998: 愛媛大学, 医学部・附属病院, 講師 1998: Ehime University Hospital, Assistant Professor, 医学部附属病院, 講師 1997: 愛媛大学, 医学部, 助手 1995: Ehime University, School of Medicine Lecture, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Neurosurgery / Cerebral neurosurgery Except Principal Investigator Cerebral neurosurgery / Neurosurgery
Keywords	Principal Investigator Bcl family / mitochondria / Tunnel / apotosis / cytochrome c / cerebral vessel / vasospasm / subarachnoid hemorrahge / 集束超音波 / drug delivery system … More / 血液脳関門 / 悪性グリオーマ / ラット / 血管平滑筋 / 脳血管攣縮 / くも膜下出血 / cytochrom c / vasospsam / subarachnoid hemorrhage / Bcl familly … More Except Principal Investigator thalamus / ciliary neurotrophic factor / neurotrophic factor / water maze test / growth associated protein-43 / cerebral ischemia / 視床 / 毛様体神経栄養因子 / 神経栄養因子 / グリオーマ / グリオーマ幹細胞 / microRNA / 膠芽腫 / バイオマーカー / エクソソーム / regeneration / 神経再生 / 脳高次機能 / 脳虚血 / neuronal regeneration / intraventricular infusion / Morris water maze test / focal cerebral ischemia / 脳室内持続注入 / 塩基好性線維芽細胞成長因子 / コリンアセチルトランスフェラーゼ / マイネルト核 / モリス水迷路学習 / 実験的脳虚血 / 脳室内注入 / 水迷路学習 / 虚血脳 / 腫瘍発生 / 腫瘍幹細胞 / PLAT / 腫瘍浸潤 / 腫瘍増殖 / 癌幹細胞 / 浸潤 / 悪性グリオーマ Less

The establishment of a novel therapy and biomarker based on expression profiles of glioma specific microRNA
- Principal Investigator
  
  Kohno Shohei
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  Ehime University
集束超音波による血液脳関門解放下での遺伝子導入による新たなグリオーマ治療の開発Principal Investigator
- Principal Investigator
  
  大上史朗
- Project Period (FY)
  2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  Ehime University
Development of novel therapy for malignant gliomas based on the Comprehensive analysis of microRNA
- Principal Investigator
  
  Onishi Takanori
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  Ehime University
Apototic or necrotic changes in pathogeneseis of cerebral vasospasm after subarachnoid hemorrhagePrincipal Investigator
- Principal Investigator
  
  OHUE Shiro
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Ehime University
Role of neurotrophic factor for cerebral ischemia
- Principal Investigator
  
  KUMON Yoshiaki
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Ehime University
The of the neurotrophic factor to the ischemic brain (in the aspect of the spatial learning ability)
- Principal Investigator
  
  KUMON Yoshiaki
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Ehime University School of Medicine

All 2016 2015 2013 2004

All Journal Article Presentation Patent

[Journal Article] グリオーマ幹細胞特異的microRNAの同定と診断・治療への応用における意義2016
- Author(s)
  山下大介, 末廣諭, 高野昌平, 大上史朗, 大西丘倫
- Journal Title
  
  愛媛医学
  
  Volume: 35 Pages: 6-11
- Data Source
  KAKENHI-PROJECT-15K10335
[Journal Article] グリオーマ幹細胞特異的microRNAの同定と診断・治療への応用における意義2016
- Author(s)
  山下大介、末廣　諭、高野昌平、大上史朗、大西丘倫
- Journal Title
  
  愛媛医学
  
  Volume: 35 Pages: 6-11
- Data Source
  KAKENHI-PROJECT-25462266
[Journal Article] miR340 Suppresses the Stem-like Cell Function of Glioma-Initiating Cells by Targeting Tissue Plasminogen Activator2015
- Author(s)
  Daisuke Yamashita, Toru Kondo, Shiro Ohue, Hisaaki Takahashi, Madoka Ishikawa, Ryo Matoba, Satoshi Suehiro, Shohei Kohno, Hironobu Harada, Junya Tanaka, Takanori Ohnishi
- Journal Title
  
  Cancer Research
  
  Volume: 75 Issue: 6 Pages: 1123-1133
- DOI
  10.1158/0008-5472.can-14-0938
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K14351, KAKENHI-PROJECT-25462266
[Journal Article] The Changes of Bcl-family Protein in the Vascular Wall Cell After Subarachnoid Hemorrhage. Rat Double Hemorrhage Model.2004
- Author(s)
  Tomohiro Abe, Shiro Ohue, Shinsuke Ohta, Yoshiaki Kumon, Takanori Ohnishi
- Journal Title
  
  Vasospasm 19
  
  Pages: 47-50
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591530
[Journal Article] くも膜下出血後の攣縮血管壁細胞におけるBcl-fammilyの変化2004
- Author(s)
  安部智宏, 大上史朗, 大田信介, 他
- Journal Title
  
  脳血管攣縮 19
  
  Pages: 47-50
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591530
[Journal Article] くも膜下出血後の攣縮血管壁細胞におけるBcl-familyの変化2004
- Author(s)
  安部智則, 大上史朗, 大田信介, 他
- Journal Title
  
  脳血管攣縮 19
  
  Pages: 47-50
- Data Source
  KAKENHI-PROJECT-15591530
[Patent] グリオーマの形成・増殖阻害作用を有するmicroRNA､及びそれを用いたグリオーマ治療薬2013
- Inventor(s)
  大西丘倫、大上史朗、山下大介
- Industrial Property Rights Holder
  大西丘倫、大上史朗、山下大介
- Industrial Property Rights Type
  特許
- Filing Date
  2013
- Data Source
  KAKENHI-PROJECT-25462266
[Presentation] Identification of GIC specific microRNA (miRNA), using miRNA profiling in extracellular vesicles2016
- Author(s)
  Yamashita D, Suehiro S, Nishikawa M, Seno T, Kohno S, Ohue S, Kunieda T, Ohnishi T
- Organizer
  13th Asian Society for Neuro-Oncology Meeting & 9th COGNO Annual Scientific Meeting
- Place of Presentation
  Sheraton on the Park（Sydney, Australia）
- Year and Date
  2016-09-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10335
[Presentation] 体液中エクソソーム内に存在するグリオーマ幹細胞特異的microRNAの同定－新規診断マーカーおよび治療薬としての可能性－2016
- Author(s)
  山下大介、末廣諭、西川真弘、瀬野利太、高野昌平、大上史朗、國枝武治、大西丘倫
- Organizer
  第75回日本脳神経外科学会学術総会
- Place of Presentation
  福岡国際会議場（福岡県福岡市）
- Year and Date
  2016-09-29
- Data Source
  KAKENHI-PROJECT-15K10335
[Presentation] エクソソーム内microRNAプロファイリングによるグリオーマ幹細胞特異的microRNAの同定2015
- Author(s)
  山下大介、末廣諭、高野昌平、大上史朗、近藤亨、大西丘倫
- Organizer
  第33回日本脳腫瘍学会学術集会
- Place of Presentation
  グランドプリンスホテル京都、京都府京都市左京区
- Year and Date
  2015-12-06
- Data Source
  KAKENHI-PROJECT-15K10335
[Presentation] miR-340 acts as a tumor suppressor in tumorigenesis of human glioma-initiating cells by targeting tissue2015
- Author(s)
  Yamashita D, Kondo T, Takahashi H, Suehiro S, Kohno S, Ohue S, Ohnishi T
- Organizer
  20th Annual Scientific Meeting and Education Day of the Society for Neuro-Oncology
- Place of Presentation
  San ANtonio,USA
- Year and Date
  2015-11-20
- Data Source
  KAKENHI-PROJECT-25462266
[Presentation] エキソーム内microRNAプロファイリングによるグリオーマ幹細胞特異的microRNAの同定2015
- Author(s)
  山下大介、末廣諭、高野昌平、大上史朗、近藤亨、大西丘倫
- Organizer
  第33回日本脳腫瘍学会学術集会
- Place of Presentation
  京都府京都市　グランドプリンスホテル京都
- Year and Date
  2015-12-08
- Data Source
  KAKENHI-PROJECT-25462266
[Presentation] Glioma形成に関わる新規microRNAの機能解析及びその標的遺伝子の同定2013
- Author(s)
  山下大介、近藤亨、高野昌平、大上史朗、大西丘倫
- Organizer
  第31回日本脳腫瘍学会学術集会
- Place of Presentation
  宮崎市
- Data Source
  KAKENHI-PROJECT-25462266
[Presentation] Identification and characterization of a novel microRNA involved in gliomagenesis2013
- Author(s)
  Yamashita D, Kondo T, Inoue A, Kohno S, Ohue S, Ohnishi T
- Organizer
  4th Quadrennial Meeting of the World Federation of Neuro-Oncology
- Place of Presentation
  San Francisco, CA
- Data Source
  KAKENHI-PROJECT-25462266

1. Kono Shohei (70467851)

# of Collaborated Projects: 3 results

# of Collaborated Products: 9 results
2. Onishi Takanori (70233210)

# of Collaborated Projects: 3 results

# of Collaborated Products: 9 results
3. KUMON Yoshiaki (80127894)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. 山下大介 (30750492)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
5. KOHNO Kanehisa (60145076)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 善家喜一郎 (60236130)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 田中潤也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Oue Shiro 大上 史朗

大上 史朗 オオウエ シロウ

OHUE Shiro 大上 史朗

OHUE Shiroh 大上 史朗

Research Projects

Research Products

Co-Researchers

The establishment of a novel therapy and biomarker based on expression profiles of glioma specific microRNA

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

集束超音波による血液脳関門解放下での遺伝子導入による新たなグリオーマ治療の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of novel therapy for malignant gliomas based on the Comprehensive analysis of microRNA

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Apototic or necrotic changes in pathogeneseis of cerebral vasospasm after subarachnoid hemorrhagePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Role of neurotrophic factor for cerebral ischemia

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The of the neurotrophic factor to the ischemic brain (in the aspect of the spatial learning ability)

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] グリオーマ幹細胞特異的microRNAの同定と診断・治療への応用における意義2016

Author(s)

Journal Title

Data Source

[Journal Article] グリオーマ幹細胞特異的microRNAの同定と診断・治療への応用における意義2016

Author(s)

Journal Title

Data Source

[Journal Article] miR340 Suppresses the Stem-like Cell Function of Glioma-Initiating Cells by Targeting Tissue Plasminogen Activator2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The Changes of Bcl-family Protein in the Vascular Wall Cell After Subarachnoid Hemorrhage. Rat Double Hemorrhage Model.2004

Author(s)

Journal Title

Description

Data Source

[Journal Article] くも膜下出血後の攣縮血管壁細胞におけるBcl-fammilyの変化2004

Author(s)

Journal Title

Description

Data Source

[Journal Article] くも膜下出血後の攣縮血管壁細胞におけるBcl-familyの変化2004

Author(s)

Journal Title

Data Source

[Patent] グリオーマの形成・増殖阻害作用を有するmicroRNA､及びそれを用いたグリオーマ治療薬2013

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

Filing Date

Data Source

[Presentation] Identification of GIC specific microRNA (miRNA), using miRNA profiling in extracellular vesicles2016

Author(s)

Organizer

Place of Presentation

Oue Shiro 大上史朗

大上史朗オオウエシロウ

OHUE Shiro 大上史朗

OHUE Shiroh 大上史朗

[Presentation] 体液中エクソソーム内に存在するグリオーマ幹細胞特異的microRNAの同定－新規診断マーカーおよび治療薬としての可能性－2016