KAITO Masahiko 垣内雅彦

Researcher Number	70214244
External Links
Affiliation (based on the past Project Information) *help	2007: 三重大, 医学(系)研究科(研究院), 助教授 2007: Mie University, Graduate School of Medicine, Associate Professor 2006: 三重大学, 大学院医学系研究科, 助教授 2005: 三重大学, 大学院・医学系研究科, 助教授 1997 – 2002: 三重大学, 医学部, 講師 1992 – 1996: 三重大学, 医学部, 助手 1994: 三重大学。医学部, 助手
Review Section/Research Field	Principal Investigator Gastroenterology / Gastroenterology Except Principal Investigator Gastroenterology / Gastroenterology
Keywords	Principal Investigator ELECTRON MICROSCOPE / HEPATITIS C VIRUS / 電子顕微鏡 / C型肝炎ウイルス / ウイルス粒子 / PLASMA / PCR METHOD / VIRUS PARTICLE / GPT / 血漿 … More / モノクローナル抗体 / PCR法 / 金コロイド / 免疫電子顕微鏡 / IRON RESTRICTION / LACTOFERRIN / VIRUS VECTOR / IMMUNOHISTOCHEMISTRY / IMMUNOELECTRON MICROSCOPY / CELL CULTURE / 鉄製限食 / 鉄制限食 / ラクトフェリン / ウイルスベクター / 免疫組織化学 / 培養細胞 / COREPARTICLE / MONOCLONALANTIBODY / COLLOIDALGOLD / コア粒子 / ALANITE AMINOTRANSFERASE / MONOCLONAL ANTIBODY / COLLOIDAL GOLD / 局在 / 肝細胞 / C型肝炎ウイルス(HCV) … More Except Principal Investigator C型肝炎ウイルス / IMY細胞 / immunogold electron microscopy / hepatitis C virus (HCV) / 金コロイド免疫電顕法 / C型肝炎ウイルス(HCV) / immunoelectron microscopy / COS cell / Huh7.5 cell / IMY-N9 cell / in vitro multiplication / hepatitis C virus / COS7細胞 / 免疫電子顕微鏡 / COS細胞 / Huh7.5細胞 / IMY-N9細胞 / 試験管内増殖 / IMY cell / HCV virion / HCV core particle / HCV RNA / HCVコア蛋白質 / RTD-PCR / 回転焼付け法 / 金コロイド免疫電子顕微鏡法 / HCVビリオン / HCVコア粒子 / HCVRNA / virus-like particle / non-C hepatitis / HCV particle / hepatitis C / ウイルス様粒子 / 非C型肝炎 / HCV粒子 / C型肝炎 Less

B型肝炎ウイルスレプリコン導入によるウイルス粒子と細胞傷害に関する超微形態的研究Principal Investigator
- Principal Investigator
  
  垣内雅彦
- Project Period (FY)
  2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Mie University
Immuno-ultrastructural study on in vitro multiplication of hepatitis C virus
- Principal Investigator
  
  WATANABE Shozo
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Mie University
ANALISES OF PROPAGATION PROCESS OF HEPATITIS C VIRUS IN CULTURED LIVER CELL AND APPLICATIONS FOR ANTI-VIRUS DRUGS.Principal Investigator
- Principal Investigator
  
  KAITO Masahiko
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Mie University
Ultrastructural study on the virion morphogenesis in the hepatitis C virus-infected cells
- Principal Investigator
  
  WATANABE Shozo
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Mie University
IMMUNOELECTRON MICROSCOPIC STUDY ON NEUTRALIZATION OF HEPATITIS C VIRUSPrincipal Investigator
- Principal Investigator
  
  KAITO Masahiko
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  MIE UNIVERSITY
Study on virus particle (s) in the blood of patients with hepatitis C : an evaluation of its pleomorphism
- Principal Investigator
  
  WATANABE Shozo
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Mie University
HEPATITIS C VIRUS PARTICLE DETECTED BY IMMUNOELECTRON MICROSCOPIC STUDYPrincipal Investigator
- Principal Investigator
  
  KAITO Masahiko
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  MIE UNIVERSITY
C型肝炎ウイルスの肝細胞内局在に関する免疫電子顕微鏡的研究Principal Investigator
- Principal Investigator
  
  垣内雅彦
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Mie University

All 2008 2007 2006 2005

All Journal Article Presentation

[Journal Article] Hepcidin expression in the liver:relatively low level in patients with chronic hepatitis C.2008
- Author(s)
  Fujita N, Watanabe S, Kaito M, et. al.
- Journal Title
  
  Molecular Medicine 13
  
  Pages: 97-104
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590632
[Journal Article] Ultrastructural demonstration of hepatitis Bvirus production in amouse model produced by hydrodynamic transfection.2007
- Author(s)
  Konishi M, Kaito M, WatanabeS, et. al.
- Journal Title
  
  International Journal of Molecular Medicine 20
  
  Pages: 31-36
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590632
[Journal Article] Unidentified viruslike particles are detected in plasma with elevatedALT levels:are they significant of etiological agent(s) of non-B, non-Chepatitis2007
- Author(s)
  Kaito M, Konisbi M, WatanabeS, et. al.
- Journal Title
  
  Medical Molecular Morphology 40
  
  Pages: 23-28
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590632
[Journal Article] Ultrastructural demonstration of hepatitis B virus production in a mouse model produced by hydrodynamic transfection.2007
- Author(s)
  Konishi M, Kaito M, Watanabe S, et. al.
- Journal Title
  
  International Journal of Molecular Medicine 20
  
  Pages: 31-36
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590632
[Journal Article] Hepcidin expression in the liver: relatively low level in patients with chronic hepatitis C.2007
- Author(s)
  Fujita N, Watanabe S, Kaito M, et. al.
- Journal Title
  
  Molecular Medicine 13
  
  Pages: 97-104
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590632
[Journal Article] Unidentified virus-like particles are detected in plasma with elevated ALT levels: are they significant of etiological agent(s) of non-B, non-C hepatitis?2007
- Author(s)
  Kaito M, Konishi M, Watanabe S, et. al.
- Journal Title
  
  Medical Molecular Morphology 40
  
  Pages: 23-28
- NAID
  10024379400
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590632
[Journal Article] Hepcidin expression in Molecular the liver : relatively low level in patients with chronic hepatitis C2007
- Author(s)
  Fujita, N, Watanabe, S, Kaito, M, et. al.
- Journal Title
  
  Molecular Medicine 13
  
  Pages: 97-104
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590632
[Journal Article] Unidentified virus-like particles are detected in plasma with elevated ALT levels : are they significant of etiological affend(s) of non-B non-C hepatitis?2007
- Author(s)
  Kaito, M, Konishi, M, Watanabe, S, et. al.
- Journal Title
  
  Medical Molecular Morphology 40
  
  Pages: 23-28
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590632
[Journal Article] Ultrastructural produced by hydrodynamic transfection2007
- Author(s)
  Konishi, M, Kaito, M, Watanabe, S, et. al.
- Journal Title
  
  International Journal of Molecular demonstration of hepatitis B virus production in a mouse model Medicine 20
  
  Pages: 31-36
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590632
[Journal Article] Immune complex of hepatitis C virus particles detected by immunogold electron microscopy2006
- Author(s)
  Kaito, M, Watanabe, S, et. al.
- Journal Title
  
  Journal of Gastroenterology 41
  
  Pages: 807-808
- NAID
  10018256182
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590632
[Journal Article] Morphological identification of hepatitis C virus El and E2 envelope, glycoproteins on the virion surface using immunogold electron microscopy2006
- Author(s)
  Kaito, M, Watanabe, S, Konishi, M, et. al.
- Journal Title
  
  International Journal of Molecular Medicine 18
  
  Pages: 673-678
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590632
[Journal Article] Circulating level of large splice variants of tenascin-C is a marker of piecemeal necrosis activity in patients with chronic hepatitis C.2006
- Author(s)
  Tanaka H, Kaito M, Watanabe S, et al.
- Journal Title
  
  Liver International 26(3)
  
  Pages: 311-318
- Data Source
  KAKENHI-PROJECT-17590632
[Journal Article] siRNA-resistance in treated HCV replicon cells is correlated with the development of specific HCV mutations.2006
- Author(s)
  Konishi M, Kaito M, Watanabe S, et. al.
- Journal Title
  
  Journal of Viral Hepatitis 13
  
  Pages: 756-761
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590632
[Journal Article] Morphology of hepatitis C and hepatitis B virus particles as detected by immunogold electron microscopy2006
- Author(s)
  Kaito, M, Konishi, M, Watanabe, S, et. al.
- Journal Title
  
  Medical Molecular Morphology 39
  
  Pages: 63-71
- NAID
  10020337947
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590632
[Journal Article] Elevation of 8-isoprostane in patients with hepatitis C virus infection undergoing hemodialysis.2006
- Author(s)
  Ishihara T, Kaito M, et al.
- Journal Title
  
  Journal of Clinical Virology 37(3)
  
  Pages: 231-232
- Data Source
  KAKENHI-PROJECT-17590632
[Journal Article] Morphology of hepatitis C and hepatitis B virus particles as detected by immunogold electron microscopy.2006
- Author(s)
  Kaito M, Konishi M, Watanabe S, et. al.
- Journal Title
  
  Medical Molecular Morphology 39
  
  Pages: 63-71
- NAID
  10020337947
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590632
[Journal Article] siRNA-resistance in treated HCV replicon cells is correlated with the development of specific HCV mutations2006
- Author(s)
  Konishi, M, Kaito, M, Watanabe, S, et. al.
- Journal Title
  
  Journal of Viral Hepatitis 13
  
  Pages: 756-761
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590632
[Journal Article] Morphological identification of hepatitis C virus E1 and E2 envelope glycoproteins on the virion surface using immunogold electron microscopy.2006
- Author(s)
  Kaito M, Watanabe S, Konishi M, et al.
- Journal Title
  
  International Journal of Molecular Medicine 18(4)
  
  Pages: 673-678
- Data Source
  KAKENHI-PROJECT-17590632
[Journal Article] Iron reduction therapy by phlebotomy reduces lipid peroxidation and oxidative stress in patients with chronic hepatitis C.2006
- Author(s)
  Kaito M, Watanabe S, et al.
- Journal Title
  
  Journal of Gastroenterology 41(9)
  
  Pages: 919-922
- NAID
  10020626471
- Data Source
  KAKENHI-PROJECT-17590632
[Journal Article] Morphology of hepatitis C and hepatitis B virus particles as detected by immunogold electron microscopy.2006
- Author(s)
  Kaito M, Konishi M, Watanabe S, et al.
- Journal Title
  
  Medical Molecular Morphology 39(2)
  
  Pages: 63-71
- NAID
  10020337947
- Data Source
  KAKENHI-PROJECT-17590632
[Journal Article] Morphological identification of hepatitis C virus El and E2 envelope glycoproteins on the virion surface using immunogold electron microscopy.2006
- Author(s)
  Kaito M, Watanabe S, Konishi M, et. al.
- Journal Title
  
  International Journal of Molecular Medicine 18
  
  Pages: 673-678
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590632
[Journal Article] siRNA-resistance in treated HCV replicon cells is correlated with the development of specific HCV mutations.2006
- Author(s)
  Konishi M, Kaito M, Watanabe S, et al.
- Journal Title
  
  Journal of Viral Hepatitis 13(11)
  
  Pages: 756-761
- Data Source
  KAKENHI-PROJECT-17590632
[Journal Article] Immune complex of hepatitis C virus particles detected by immunogold electron microscopy.2006
- Author(s)
  Kaito M, Watanabe S, et al.
- Journal Title
  
  Journal of Gastroenterology 41(8)
  
  Pages: 807-808
- NAID
  10018256182
- Data Source
  KAKENHI-PROJECT-17590632
[Journal Article] Increased lipid peroxidation in patients with non-alcoholic fatty liver disease and chronic hepatitis C as measured by the plasma level of 8-isoprostane.2006
- Author(s)
  Konishi M, Watanabe S, Kaito M, et al.
- Journal Title
  
  Journal of Gastroenterology and Hepatology 21(12)
  
  Pages: 1821-1825
- Data Source
  KAKENHI-PROJECT-17590632
[Journal Article] Lactoferrin inhibits lipid peroxidation in patients with chronic hepatitis C.2006
- Author(s)
  Konishi Mq, Watanabe S, Kaito M, et al.
- Journal Title
  
  Hepatology Research 36(1)
  
  Pages: 27-32
- NAID
  10018774288
- Data Source
  KAKENHI-PROJECT-17590632
[Journal Article] Effects of bezafibrate in patients with chronic hepatitis C virus infection : combination with interferon and ribavirin.2006
- Author(s)
  Fujita N, Kaito M, Konishi M, Watanabe S, et al.
- Journal Title
  
  Journal of Viral Hepatitis 13(7)
  
  Pages: 441-448
- Data Source
  KAKENHI-PROJECT-17590632
[Journal Article] Accumulation of 8-nitroguanine in the liver of chronic hepatitis C patients without sustained virological response after completion of interferon therapy.2006
- Author(s)
  Kaito M, et al.
- Journal Title
  
  Journal of Gastroenterology 41(7)
  
  Pages: 713-714
- NAID
  10019282504
- Data Source
  KAKENHI-PROJECT-17590632
[Journal Article] Morphology of hepatitis C and hepatitis B virus particles as detected by nimmunogold electron microscopy.2006
- Author(s)
  M.Kaito, N.Fujita, M.Konishi, S.Watanabe, et al.
- Journal Title
  
  Medical Molecular Morphology (in press)
- Data Source
  KAKENHI-PROJECT-17590632
[Journal Article] Iron content and consumption of health foods by patients with chronic hepatitis C.2006
- Author(s)
  Iwata K, Watanabe S, Kaito M, et al.
- Journal Title
  
  Journal of Gastroenterology 41(9)
  
  Pages: 919-920
- NAID
  10020626466
- Data Source
  KAKENHI-PROJECT-17590632
[Journal Article] Immune complex of hepatitis C virus particles detected by immunogold electron microscopy.2006
- Author(s)
  Kaito M, Watanabe S, et. al.
- Journal Title
  
  Journal of Gastroenterology 41
  
  Pages: 807-808
- NAID
  10018256182
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590632
[Journal Article] Hepatitis C virus free-virion and immune-complex dynamics during interferon therapy with and without ribabirin in genotype-1b chronic hepatitis C patients.2006
- Author(s)
  N.Fujita, M.Kaito, M.Konishi, S.Watanabe, et al.
- Journal Title
  
  Journal of Viral Hepatitis 2006・1
  
  Pages: 190-198
- Data Source
  KAKENHI-PROJECT-17590632
[Presentation] Expression and regulation of transferin receptor 2 in hepatitis C virus gene- transfected Society of liver cells. (in Japanese)2007
- Author(s)
  Kobayashi, Y, Konishi, M, Kaito, M, Watanabe, S, et. al.
- Organizer
  37th West branch meeting of the Japan Society of Hepatology
- Place of Presentation
  Nagasaki
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590632
[Presentation] C型肝炎ウイルス遺伝子導入肝細胞におけるトランスフェリンレセプター2の発現調節2007
- Author(s)
  小林由直、小西正芳、垣内雅彦、渡邉省三、他
- Organizer
  第37回日本肝臓学会西部会
- Place of Presentation
  長崎市
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590632
[Presentation] C型肝炎ウイルス遺伝子導入肝細胞におけるトランスフェリンレセプター2の発現調節2007
- Author(s)
  小林由直、小西正芳、垣内雅彦、渡邉省三, 他
- Organizer
  第37回日本肝臓学会西部会
- Place of Presentation
  長崎ブリックホール
- Data Source
  KAKENHI-PROJECT-17590632
[Presentation] Suppression of HCV multiplication and appearance of mutant in target region by siRNA (examination using HCV replicon cells) (in Japanese)2005
- Author(s)
  Konishi, M, Kaito, M, Watanabe, S, et. al.
- Organizer
  41st General meeting of the Japan Society of Hepatology
- Place of Presentation
  Osaka
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590632
[Presentation] siRNAによるHCV増殖抑制効果とsiRNA標的領域のmutantの出現(HCVreplicon細胞を用いた検討)2005
- Author(s)
  小西正芳, 垣内雅彦、渡邉省三、他
- Organizer
  第41回日本肝臓学会総会
- Place of Presentation
  大阪市
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590632

1. WATANABE Shozo (20134934)

# of Collaborated Projects: 7 results

# of Collaborated Products: 34 results
2. IKOMA Jiro (80283521)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. KOHARA Michinori (10250218)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. KONISHI Masayoshi (00397514)

# of Collaborated Projects: 1 results

# of Collaborated Products: 24 results

KAITO Masahiko 垣内 雅彦

Research Projects

Research Products

Co-Researchers

B型肝炎ウイルスレプリコン導入によるウイルス粒子と細胞傷害に関する超微形態的研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Immuno-ultrastructural study on in vitro multiplication of hepatitis C virus

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ANALISES OF PROPAGATION PROCESS OF HEPATITIS C VIRUS IN CULTURED LIVER CELL AND APPLICATIONS FOR ANTI-VIRUS DRUGS.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Ultrastructural study on the virion morphogenesis in the hepatitis C virus-infected cells

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

IMMUNOELECTRON MICROSCOPIC STUDY ON NEUTRALIZATION OF HEPATITIS C VIRUSPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study on virus particle (s) in the blood of patients with hepatitis C : an evaluation of its pleomorphism

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

HEPATITIS C VIRUS PARTICLE DETECTED BY IMMUNOELECTRON MICROSCOPIC STUDYPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

C型肝炎ウイルスの肝細胞内局在に関する免疫電子顕微鏡的研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Hepcidin expression in the liver:relatively low level in patients with chronic hepatitis C.2008

Author(s)

Journal Title

Data Source

[Journal Article] Ultrastructural demonstration of hepatitis Bvirus production in amouse model produced by hydrodynamic transfection.2007

Author(s)

Journal Title

Data Source

[Journal Article] Unidentified viruslike particles are detected in plasma with elevatedALT levels:are they significant of etiological agent(s) of non-B, non-Chepatitis2007

Author(s)

Journal Title

Data Source

[Journal Article] Ultrastructural demonstration of hepatitis B virus production in a mouse model produced by hydrodynamic transfection.2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] Hepcidin expression in the liver: relatively low level in patients with chronic hepatitis C.2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] Unidentified virus-like particles are detected in plasma with elevated ALT levels: are they significant of etiological agent(s) of non-B, non-C hepatitis?2007

Author(s)

Journal Title

NAID

Description

Data Source

KAITO Masahiko 垣内雅彦