TANAKA Junya 田中潤也

… Alternative Names

田中潤也タナカジユンヤ

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Researcher Number	70217040
Other IDs
External Links
Affiliation (Current)	2022: 愛媛大学, 医学系研究科, 教授
Affiliation (based on the past Project Information) *help	2020: 愛媛大学, 医学系研究科, 教授 2016 – 2018: 愛媛大学, 医学系研究科, 教授 2015 – 2016: 愛媛大学, 大学院医学系研究科, 教授 2013 – 2015: 愛媛大学, 医学(系)研究科(研究院), 教授 2013: 愛媛大学, 大学院・医学系研究科, 教授 … More 2013: 愛媛大学, 大学院医学系研究科, 教授 2009 – 2012: Ehime University, プロテオ医学研究センター, 教授 2007: Ehime University, Graduate School of Medicine, Professor 2006: 愛媛大学, 大学院医学系研究科, 教授 1999 – 2005: MEDICINE, EHIME UNIV, PROFESSOR, 医学部, 教授 1998: 愛媛大学, 医学部, 助教授 1989 – 1993: 大阪大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Cerebral neurosurgery / Orthopaedic surgery / General physiology / Neuroscience in general / Urology / Neurochemistry/Neuropharmacology / Medium-sized Section 46:Neuroscience and related fields Except Principal Investigator Cerebral neurosurgery / Pediatrics / Cerebral neurosurgery … More / General medical chemistry / 医学一般 / Neurosurgery / 分子細胞生物学 / Neurochemistry/Neuropharmacology Less
Keywords	Principal Investigator マイクログリア / アストロサイト / microglia / 神経細胞 / BINCs / astrocyte / 脳梗塞 / マクロファージ / 骨髄 / 脳損傷 … More / 神経系前駆細胞 / オリゴデンドロサイト / 分化転換 / 神経組織再生 / 脊髄損傷 / transdifferentiation / neuron / oligodendrocyte / トランスジェニックマウス / NG2 / 細胞移植 / MICROGLIA / ASTROCYTES / NEURON / L-Ser / GFAP / phagocytosis / regeneration / spinal cord / ProMGB / Ibal / NG2プロテオグリカン / 幹細胞 / アストログリオーシス / HSV-tk / 損傷修復 / 脳虚血 / Cre / Arf6 / ナトリウムイオン/プロトン交換輸送体1 / NHE1 / NHE1阻害剤 / 神経膠腫浸潤 / がん浸潤抑制剤 / アクチン細胞骨格再構成 / 細胞内局在 / 神経膠腫 / 細胞浸潤 / AMAP1 / 星状細胞 / 分化多能性 / 神経細胞保護作用 / 単球 / パーキンソン病 / 新規治療法 / 幹細胞性 / Iba1 / サイトカイン / 分化誘導 / アポトーシス / 細胞死抑制 / APOPTOSIS / INHIBITION OF CELL DEATH / testosterone / estradiol / Aquaprin / apolipoprotein E / progesterone / テストステロン / 性ホルモン受容体 / プロゲステロン / RT-PCR / 脳の性差形成 / アクアポーリン / アンドロゲン / アクアポーリン4 / 細胞の生存率 / タンパク質キナーゼC / ESTOSTERONE / AQUAPORIN / APOLIPOPROTEINE / 多能性幹細胞 / NG2コンドロイチン硫酸プロテオグリカン / NG2コンドロイチン硫酸ブロテオグリカン / regenerative medicine / nestin / circadian / sleep / synapse / noradrenaline / EEG / eat-me signal / シナプス / 貪食 / 睡眠覚醒リズム / 入眠覚醒リズム / グルタミン酸 / ノルアドレナリン / 社会行動 / ラット / 恋愛 / 前頭前皮質 / ミクログリア / cFos / RNAseq / sexual communication / synaptic pruning / prefrontal cortex … More Except Principal Investigator アクチン / カルデスモン / カルスペクチン / アネキシンVI / 海馬 / シナプシンI / Actin / Bcl-x_L / トロポミオシン / 細胞膜骨格 / エリスロポエチン / スナネズミ / 脳虚血 / 受動的回避学習実験 / 熱性けいれん / 内側側頭葉てんかん / てんかん / 脳梗塞 / 細胞骨格 / Caldesmon / Calspectin / アポトーシス / Cerebral ischemia / ミオシン / src遺伝子産物 / 神経成長円錐 / カルシウムイオン / ゲルゾリン / 細胞接着 / スプライシング / プロモーター / 神経細胞 / マイクログリア / 遅発性神経細胞死 / けいれん重積 / サイトカイン / 動物モデル / 熱性痙攣重積 / ラット / 熱性痙攣 / HMGB1 / カルパクチンI / エクソサイト-シス / Calpactin I / Exocytosis / 燐脂質 / シナプス小胞 / Annexin VI / 一酸化窒素 / Bax / RT-PCR / ウエスタンブロット / 一過性前脳虚血 / bcl-2 / apoptosis / Stat3 / cerebral ischemia / SOCS3 / Neural stem cell / Neurogenesis / 動的接着構造 / 形質変換 / 動的接着部 / アネキシンII / p60^<c-src> / PC12 / アクチンフィラメント / ラウス肉腫ウイルス / 細胞運動 / 細胞運動性 / L-セリン / グリシン / Bcl-w / アストロサイト / 神経栄養因子 / 3フォスフォグリセリン酸脱水素酵素 / エリスロポエチン由来ペプチド / 海馬硬化症 / 温熱誘導痙攣 / てんかん原性 / 炎症性サイトカイン / 幼弱脳 / 温熱誘発痙攣 / ケトン体エステル / 脱随疾患 / ケトン食療法 / EAEマウスモデル / ケトン体 / EAEモデル / NG2コンドロイチン硫酸プロテオグリカン / TGF-β1 / TGFβ1 / 側頭葉てんかん / HMGB－１ / 分子標的 / 脳波 / アストログリア / 後天性てんかん / アストログリオーシス / ヌクレオカイン / 海馬細胞障害 / 細胞骨格蛋白質 / 生化学的解析 / 超微細形態学的解析 / αーアクチニン / 細胞骨格架橋蛋白質 / 急速凍結ディ-プエッチ法 / 免疫電顕法 / Cytoskeletal Protein / Biochemical Analysis / Ultrastructural Analysis / Synapsin 1 / カルモジュリン / 平滑筋 / 形態変化 / 染色体 / オルタナティブスプライシング / hーカルデスモン / lーカルデスモン / cDNA / 平滑筋細胞の分化・脱分化 / ゲノムDNA / Calumodulin / Tropomyosin / Smooth muscle / Phenotyptic modulation / Chromosome / Alternative splicing / Ca^<2+>チャンネル / Ca^<2+>ポンプ / Membrane Skeleton / Calcium Ion / Phospholipid / 間接螢光抗体法 / 細胞内局在 / Myosin / Cytoskeleton / 平滑筋細胞 / 平滑筋細胞形質転換 / アクチン-ミオシン相互作用 / 遺伝子構造 / 転写制御 / 接着因子 / 平滑筋細胞分化 / アクトミオシン系制御 / エンハンサー / Smooth muscle cells / Phenotypic modulation / Actomyosin system / Genomic structure / Splicing / Promoter / Transcriptional regulation / カルシウム制御 / カルシウム / Membrane skeleton / Calcium regulation / Annexins / SynapsinI / Phospholipids / クリンプロスト / TEI-7165 / 乳酸脱水素酵素 / PC12細胞 / アラマーブルー / 脳卒中易発症高血圧自然発症ラット / 中大脳動脈皮質枝永久閉塞 / 場所学習障害 / Prostaglandin I2 analog / Brain ischemia / Passive avoidance task / Delayed neuronal death / Apoptosis / 細胞死 / 虚血傷害 / 低酸素傷害 / 海馬CA1領域 / 細胞死関連遺伝子群 / Erythropoietin / Cell death / 神経細胞二次変性 / プロサポシン関連ペプチド / 神経細胞の二次変性 / インターロイキン3 / ジンセノサイドRb_1 / secondary neuronal degeneration / gerbil / hippocampus / prosaposin-related peptide / passive avoidance experiment / 微小循環 / 酸素輸送 / 赤血球レオロジー / 人工微小流路 / 脳血流 / 神経組織 / 誘発電位 / 画像処理 / 酸素放出 / 赤血球集合 / 重力 / 血流量 / 微小血管 / 脳循環 / トリグリセリド / 腸間膜微小血管網 / 赤血球 / 酸素飽和度 / Microcirculation / Oxygen transport / Red blood cell rheology / Artificial micro-flow channel / Cerebral blood flow / Nervous tissues / Evoked potential / Image processing / 神経細胞死 / cytokine / Neuronal death / Neurigenesis / neurogenesis / neural stem cell / クロマフィン顆粒 / 副腎髄質 / 神経シナプス / エクソサイトーシス / Ca^<2+>結合蛋白質 / カルモデュリン / Ca^<2+>制御 / Synaptic vesicles / Chromaffin granules / Synapsis 1 / 膠芽腫 / グリオーマ / Oct-3/4 / 化合物スクリーニング / 腫瘍幹細胞 / 浸潤 / 薬剤耐性 / MGMT / テモゾロミド / DNAメチル化 / ABCトランスポーター / Toll様受容体 / リポ多糖 / PolyI:C / 炎症性メディエーター / 分子標的療法 / 神経免疫 / オキシトシン受容体 / オキシトシン Less

Heterosexual communication and microglial synaptic pruningPrincipal Investigator
- Principal Investigator
  
  田中潤也
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 46:Neuroscience and related fields
- Research Institution
  Ehime University
Toll様受容体を介す熱性痙攣と続発性てんかんの病態解明と新規分子標的療法の開発
- Principal Investigator
  
  福田光成
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Ehime University
Development of Oct-3/4 targeting drug for malignant glioma treatment
- Principal Investigator
  
  Takahashi Hisaaki
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  Hokuriku University
  Asahikawa Medical College
Involvement of microglial cells in the sleep/wake cyclePrincipal Investigator
- Principal Investigator
  
  Tanaka Junya
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Ehime University
Expression of oxytocin receptor in a rat stroke model
- Principal Investigator
  
  Sugimoto Kana
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurosurgery
- Research Institution
  Osaka University
High mobility group box 1 enhanced febrile seizures and acquired epilepsy in a rodent model of infantile febrile seizures
- Principal Investigator
  
  Fukuda Mitsumasa
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Ehime University
Activated microglia in a rat stroke model express NG2 proteoglycan in peri-infarct tissue through the involvement of TGF-beta1
- Principal Investigator
  
  SUGIMOTO Kana
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Osaka University
  Ehime University
Protective effects of Ketone-bodies against demyelinating disease
- Principal Investigator
  
  SUZUKI Yuka
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Ehime University
Determination of cell type(s) that should be transplanted into lesion core of the brain for better outcomePrincipal Investigator
- Principal Investigator
  
  TANAKA Junya
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Ehime University
Multipotential stem cell-like nature of bone marrow-derived macrophages accumulated in lesion core of acute and severe brain injuries.Principal Investigator
- Principal Investigator
  
  TANAKA Junya
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General physiology
- Research Institution
  Ehime University
Mechanism and prevention strategy for mesial temporallobe epilepsy following febrile status convulsion
- Principal Investigator
  
  FUKUDA Mitsumasa
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Ehime University
神経膠腫細胞浸潤におけるArf6依存性および非依存性の意義Principal Investigator
- Principal Investigator
  
  田中潤也
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Ehime University
The effects of SOCS3 on neural stem cell fate and feasibility of the SOCS3-overexpressingneural stem cells for stake therapy
- Principal Investigator
  
  HATA Ryuji
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Ehime University
トランスジェニックマウスを用いたマイクログリアによる脳損傷修復システムの解明Principal Investigator
- Principal Investigator
  
  田中潤也
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Ehime University
Development of novel therapeutic means to regenerating spinal cord injury using microglia/macrophagesPrincipal Investigator
- Principal Investigator
  
  TANAKA Junya
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  EHIME UNIVERSITY
Molecular mechanism of cerebral ischemia through Jak-Stat signaling
- Principal Investigator
  
  HATA Ryuji
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Ehime University
革命的脊髄損傷治療法の開発:骨髄細胞あるいは末梢血から中枢神経組織を作るPrincipal Investigator
- Principal Investigator
  
  田中潤也
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Ehime University
エリスロポエチン由来ペプチドの神経細胞死抑止効果と作用機構解析
- Principal Investigator
  
  阪中雅広
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Ehime University
The role of sex steroid on the generation of sex differences in the brain development with special attention to androgen.Principal Investigator
- Principal Investigator
  
  TANAKA Junya
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Urology
- Research Institution
  Ehime University
L-セリンとグリシンの神経細胞死抑止機序解明と神経疾患治療への応用可能性の検討
- Principal Investigator
  
  SAKANAKA Masahiro
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Ehime University
Comprehensive analyses of blood circulation, oxygen transport and neural activity in microcirculatory level of brain
- Principal Investigator
  
  MAEDA Nobuji
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Ehime University
Protective effects of erythropoietin on ischemic brain
- Principal Investigator
  
  SAKANAKA Masahiro
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Ehime University
Development of factors that prevent secondary neuronal degeneration
- Principal Investigator
  
  DESAKI Junzo
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Ehime University
Protection of the ischemic brain by a new prostaglandin I2 analog clinprost
- Principal Investigator
  
  SAKANAKA Masahiro
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Ehime University
PURIFICATION AND CHARACTERZATION OF GLIA-DERIVED NEUROPROTECTIVE FACTORSPrincipal Investigator
- Principal Investigator
  
  TANAKA Junya
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neuroscience in general
- Research Institution
  EHIME UNIVERSITY
がん細胞に特有な細胞接着構造の分子構築の解明
- Principal Investigator
  
  祖父江憲治
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Osaka University
細胞骨格系による中枢シナプス機能発現の分子機作に関する研究
- Principal Investigator
  
  祖父江憲治
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
Molecular Mechanism of the differentiation of smooth muscle cells
- Principal Investigator
  
  SOBUE Kenji
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Osaka University
Interaction of annexins with membrane skeletal proteins in brain
- Principal Investigator
  
  INUI Makoto
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Osaka University
細胞骨格系による中枢シナプス機能発現に分子機作に関する研究
- Principal Investigator
  
  祖父江憲治
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
Analyzes of dynamic molecular organization of the membrane skeleton
- Principal Investigator
  
  SOBUE Kenji
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  医学一般
- Research Institution
  Osaka University
癌細胞動的接着部の分子構築の解析
- Principal Investigator
  
  祖父江憲治
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Osaka University
Analysis for the Expressional Change of Caldesmon Isoforms during Phenotyptic Modulation of Smooth Muscle Cells
- Principal Investigator
  
  SOBUE Kenji
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Osaka University
Interaction between ion channels and membrane skeleton
- Principal Investigator
  
  INUI Makoto
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  分子細胞生物学
- Research Institution
  Osaka University
がん細胞接着部における細胞接着因子と細胞膜裏打ち構造の役割
- Principal Investigator
  
  SOBUE Kenji
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Osaka University
A New Method for the Analyses of Cytoskeletal and Their Related Proteins
- Principal Investigator
  
  SOBUE Kenji
- Project Period (FY)
  1989 – 1991
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research
- Research Field
  
  医学一般
- Research Institution
  Osaka University
Role of Cytoskeletal System and its Regulation by Ca^<2+> in Exocytosis
- Principal Investigator
  
  SOBUE Kenji
- Project Period (FY)
  1988 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Osaka University

[Journal Article] Snapshot of microglial physiological functions2021
- Author(s)
  Verkhratsky Alexei、Sun Dandan、Tanaka Junya
- Journal Title
  
  Neurochemistry International
  
  Volume: 144 Pages: 104960-104960
- DOI
  10.1016/j.neuint.2021.104960
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21465
[Journal Article] Generation of CSF-1 independent ramified microglia from leptomeninges in vitro.2021
- Author(s)
  Tanaka J, Takahashi H, Yano H, Nakanishi H.
- Journal Title
  
  Cells
  
  Volume: 10 Pages: 24-24
- DOI
  10.3390/cells10010024
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09333, KAKENHI-PROJECT-20K21465, KAKENHI-PROJECT-18K19650
[Journal Article] Synaptic elimination by microglia and disturbed higher brain functions2021
- Author(s)
  Miyanishi Kazuya、Sato Arisa、Kihara Nanako、Utsunomiya Ryo、Tanaka Junya
- Journal Title
  
  Neurochemistry International
  
  Volume: 142 Pages: 104901-104901
- DOI
  10.1016/j.neuint.2020.104901
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K21465
[Journal Article] Microglial metabolic disturbances and neuroinflammation in cerebral infarction2021
- Author(s)
  Takeda Haruna、Yamaguchi Teruaki、Yano Hajime、Tanaka Junya
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 145 Pages: 130-139
- DOI
  10.1016/j.jphs.2020.11.007
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21465
[Journal Article] CD44 expression in the tumor periphery predicts the responsiveness to bevacizumab in the treatment of recurrent glioblastoma2021
- Author(s)
  Nishikawa Masahiro、Inoue Akihiro、Ohnishi Takanori、Yano Hajime、Kanemura Yonehiro、Kohno Shohei、Ohue Shiro、Ozaki Saya、Matsumoto Shirabe、Suehiro Satoshi、Nakamura Yawara、Shigekawa Seiji、Watanabe Hideaki、Kitazawa Riko、Tanaka Junya、Kunieda Takeharu
- Journal Title
  
  Cancer Medicine
  
  Volume: 10 Pages: 2013-2025
- DOI
  10.1002/cam4.3767
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08997, KAKENHI-PROJECT-20K21465
[Journal Article] Lister hooded rats as a novel animal model of attention-deficit/hyperactivity disorder2020
- Author(s)
  Jogamoto Toshihiro、Utsunomiya Ryo、Sato Arisa、Kihara Nanako、Choudhury Mohammed E.、Miyanishi Kazuya、Kubo Madoka、Nagai Masahiro、Nomoto Masahiro、Yano Hajime、Shimizu Yusuke I.、Fukuda Mitsumasa、Ishii Eiichi、Eguchi Mariko、Tanaka Junya
- Journal Title
  
  Neurochemistry International
  
  Volume: 141 Pages: 104857-104857
- DOI
  10.1016/j.neuint.2020.104857
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08866, KAKENHI-PROJECT-20K06856, KAKENHI-PROJECT-20K21465
[Journal Article] Activated microglia-derived macrophage-like cells exacerbate brain edema after ischemic stroke correlate with astrocytic expression of aquaporin-4 and interleukin-1 alpha release2020
- Author(s)
  Murata Yukie、Sugimoto Kana、Yang Chihpin、Harada Kazuo、Gono Rina、Harada Teiji、Miyashita Yohei、Higashisaka Kazuma、Katada Ryuichi、Tanaka Junya、Matsumoto Hiroshi
- Journal Title
  
  Neurochemistry International
  
  Volume: 140 Pages: 104848-104848
- DOI
  10.1016/j.neuint.2020.104848
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K10125, KAKENHI-PROJECT-19K09456, KAKENHI-PROJECT-20K21465
[Journal Article] Microglia and Macrophages in the Pathological Central and Peripheral Nervous Systems2020
- Author(s)
  Abe N, Nishihara T, Yorozuya T, Tanaka J
- Journal Title
  
  Cells
  
  Volume: 9 Pages: 2132-2132
- DOI
  10.3390/cells9092132
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09436, KAKENHI-PROJECT-20K21465
[Journal Article] Significance of Glioma Stem-Like Cells in the Tumor Periphery That Express High Levels of CD44 in Tumor Invasion, Early Progression, and Poor Prognosis in Glioblastoma.2018
- Author(s)
  Masahiro Nishikawa, Akihiro Inoue, Takanori Ohnishi, Shohei Kohno, Shiro Ohue, Shirabe Matsumoto, Satoshi Suehiro, Daisuke Yamashita, Saya Ozaki, Hideaki Watanabe, Hajime Yano, Hisaaki Takahashi, Riko Kitazawa, Junya Tanaka, Takeharu Kunieda
- Journal Title
  
  Stem Cells Int.
  
  Volume: 23 Pages: 5387041-5387041
- DOI
  10.1155/2018/5387041
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08997, KAKENHI-PROJECT-15K10324
[Journal Article] Truncated CD200 stimulates tumor immunity leading to fewer lung metastases in a novel Wistar rat metastasis model.2018
- Author(s)
  Kuwabara Jun、Umakoshi Akihiro、Abe Naoki、Sumida Yutaro、Ohsumi Shota、Usa Eika、Taguchi Kana、Choudhury Mohammed E.、Yano Hajime、Matsumoto Shirabe、Kunieda Takeharu、Takahashi Hisaaki、Yorozuya Toshihiro、Watanabe Yuji、Tanaka Junya
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 496 Pages: 542-548
- DOI
  10.1016/j.bbrc.2018.01.065
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K10809, KAKENHI-PROJECT-16K20014, KAKENHI-PROJECT-18K16587, KAKENHI-PROJECT-17K16650, KAKENHI-PROJECT-15K10324
[Journal Article] High mobility group box 1 enhances hyperthermia-induced seizures and secondary epilepsy associated with prolonged hyperthermia-induced seizures in developing rats2017
- Author(s)
  Ito Masanori、Takahashi Hisaaki、Yano Hajime、Shimizu Yusuke I.、Yano Yoshiaki、Ishizaki Yoshito、Tanaka Junya、Ishii Eiichi、Fukuda Mitsumasa
- Journal Title
  
  Metabolic Brain Disease
  
  Volume: 32 Pages: 2095-2104
- DOI
  10.1007/s11011-017-0103-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10809, KAKENHI-PROJECT-16K09990
[Journal Article] Blood vessels expressing CD90 in human and rat brain tumors.2016
- Author(s)
  Akihiro Inoue, Junya Tanaka, Hisaaki Takahashi, Shohei Kohno, Shiro Ohue, Akihiro Umakoshi, Katsuhiro Gotoh, Takanori Ohnishi
- Journal Title
  
  Neuropathology
  
  Volume: 36 Pages: 168-180
- DOI
  10.1111/neup.12244
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K14351, KAKENHI-PROJECT-15K10324
[Journal Article] Treadmill exercise ameliorates ischemia-induced brain edema while suppressing Na(+)/H(+) exchanger 1 expression2016
- Author(s)
  Ryutaro Nishioka, Kana Sugimoto, Hitomi Aono, Ayano Mise, Mohammed E. Choudhury, Kazuya Miyanishi, Afsana Islam, Takahiro Fujita, Haruna Takeda, Hisaaki Takahashi, Hajime Yano, Junya Tanaka
- Journal Title
  
  Exp Neurol.
  
  Volume: 277 Pages: 150-161
- DOI
  10.1016/j.expneurol.2015.12.016
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K10809, KAKENHI-PROJECT-15K14351, KAKENHI-PROJECT-26861150, KAKENHI-PROJECT-15K10324, KAKENHI-PROJECT-16K10721
[Journal Article] A Truncated form of CD200 (CD200S) Expressed on Glioma Cells Prolonged Survival in a Rat Glioma Model by Induction of a Dendritic Cell-Like Phenotype in Tumor-Associated Macrophages2016
- Author(s)
  Kana Kobayashi, Hajime Yano, Akihiro Umakoshi, Shirabe Matsumoto, Ayano Mise, Yu Funahashi, Yoshitomo Ueno, Yoshiaki Kamei, Yasutsugu Takada, Yoshiaki Kumon, Takanori Ohnishi, and Junya Tanaka*
- Journal Title
  
  NEOPLASIA
  
  Volume: 18 Pages: 229-241
- DOI
  10.1016/j.neo.2016.02.006
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K14351, KAKENHI-PROJECT-15K10809
[Journal Article] The hypnotic bromovalerylurea ameliorates 6-hydroxydopamine-induced dopaminergic neuron loss while suppressing expression of interferon regulatory factors by microglia.2016
- Author(s)
  Hiromi Higaki, Mohammed Emamussalehin Choudhury, Chisato Kawamoto, Keisuke Miyamoto, Afsana Islam, Yurika Ishii, Kazuya Miyanishi, Haruna Takeda, Naoto Seo, Kana Sugimoto, Hisaaki Takahashi, Hajime Yano and Junya Tanaka
- Journal Title
  
  Neurochem Int.
  
  Volume: 99 Pages: 158-168
- DOI
  10.1016/j.neuint.2016.06.013
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K14351, KAKENHI-PROJECT-26861150, KAKENHI-PROJECT-15K10324, KAKENHI-PROJECT-15K10809, KAKENHI-PROJECT-16K10721
[Journal Article] miR340 suppresses the stem-like cell function of glioma-initiating cells by targeting tissue plasminogen activator2015
- Author(s)
  Daisuke Yamashita, Toru Kondo, Shiro Ohue, Hisaaki Takahashi, Madoka Ishikawa, Ryo Matoba, Satoshi Suehiro, Shohei Kohno, Hironobu Harada, Junya Tanaka, Takanori Ohnishi
- Journal Title
  
  Cancer Research
  
  Volume: 75 Pages: 1123-1133
- DOI
  10.1158/0008-5472.can-14-0938
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K14351, KAKENHI-PROJECT-25462266
[Journal Article] CD200+ and CD200- macrophages accumulated in ischemic lesions of rat brain: the two populations cannot be classified as either M1 or M2 macrophages2015
- Author(s)
  Shirabe Matsumoto, Junya Tanaka, Hajime Yano, Hisaaki Takahashi, Kana Sugimoto, Shiro Ohue, Akihiro Inoue, Hitomi Aono, Akari Kusakawa, Hideaki Watanabe, Yoshiaki Kumon, Takanori Ohnishi
- Journal Title
  
  J Neuroimmunol
  
  Volume: 282 Pages: 7-20
- DOI
  10.1016/j.jneuroim.2015.03.013
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26462162, KAKENHI-PROJECT-26861150, KAKENHI-PROJECT-15K10324, KAKENHI-PROJECT-15K10809, KAKENHI-PROJECT-15K14351
[Journal Article] miR-340 acts as atumor suppressor in tumorigenesis of human glioma-initiating cells by targeting plasminogen activator, tissue.2015
- Author(s)
  Yamashita D, Kondo T, Ohue S, Takahashi H, Ishikawa M, Matoba R, Suehiro A, Inoue A, Kohno S, Harada H, Tanaka J, Ohnishi T
- Journal Title
  
  Cancer Research
  
  Volume: 75 Pages: 1123-1133
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K10324
[Journal Article] Anti-inflammatory effects of noradrenaline on LPS-treated microglial cells: Suppression of NFkB nuclear translocation and subsequent STAT1 phosphorylation2015
- Author(s)
  Ishii Y, Yamaizumi A, Kawakami A, Islam A, Choudhury ME, Takahashi H, Yano H, Tanaka J
- Journal Title
  
  Neurochemistry International
  
  Volume: 90 Pages: 56-66
- DOI
  10.1016/j.neuint.2015.07.010
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K10324, KAKENHI-PROJECT-15K10809, KAKENHI-PROJECT-15K14351
[Journal Article] The ameliorative effects of a hypnotic bromvalerylurea in sepsis2015
- Author(s)
  Kikuchi S, Nishihara T, Kawasaki S, Abe N, Kuwabara J, Choudhury ME, Takahashi H, Yano H, Nagaro T, Watanabe Y, Aibiki M, Tanaka J
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 459 Pages: 319-326
- DOI
  10.1016/j.bbrc.2015.02.111
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K10324, KAKENHI-PROJECT-15K10809, KAKENHI-PROJECT-15K14351, KAKENHI-PROJECT-15K20343
[Journal Article] Oct-3/4 promotes tumor angiogenesis through VEGF production in glioblastoma2015
- Author(s)
  Takahashi H, Inoue A,　Kawabe Y, et al.
- Journal Title
  
  BrainTumor Pathology
  
  Volume: ３２ Pages: 31-40
- DOI
  10.1007/s10014-014-0203-3
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25861280, KAKENHI-PROJECT-26861150, KAKENHI-PROJECT-15K10324, KAKENHI-PROJECT-15K14351
[Journal Article] Oct-3/4 modulates the drug-resistant phenotype of glioblastoma cells through expression of ATP binding cassette transporter G2.2015
- Author(s)
  Hosokawa Y, Takahashi H, Inoue A,　et al.
- Journal Title
  
  Biochim Biophys Acta.
  
  Volume: １８５０ Pages: 1197-1205
- DOI
  10.1016/j.bbagen.2015.01.017
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25861280, KAKENHI-PROJECT-26861150, KAKENHI-PROJECT-15K10324, KAKENHI-PROJECT-15K14351
[Journal Article] Activated Microglia in a Rat Stroke Model Express NG2 Proteoglycan in Peri-Infarct Tissue Through the Involvement of TGF-β12014
- Author(s)
  Kana Sugimoto, Ryutaro Nishioka, Airi Ikeda, Ayano Mise, Hisaaki Takahashi, Hajime Yano, Yoshiaki Kumon, Takanori Ohnishi, Junya Tanaka
- Journal Title
  
  GLIA
  
  Volume: vol. 62, No.2 Pages: 185-198
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791507
[Journal Article] Activated microglia in a rat stroke model express NG2 proteoglycan in peri-infarct tissue through the involvement of TGF-β1.2014
- Author(s)
  SUGIMOTO Kana, NISHIOKA Ryutaro, IKEDA Airi, MISE Ayano, TAKAHASHI Hisaaki, YANO Hajime, KUMON Yoshiaki, OHNISHI Takanori, TANAKA Junya
- Journal Title
  
  GLIA
  
  Volume: 62 Pages: 185-198
- DOI
  10.1002/glia.22598
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592092, KAKENHI-PROJECT-23592130, KAKENHI-PROJECT-24791507
[Journal Article] Expression of MCP-1 and fractalkine on endothelial cells and astrocytes may contribute to the invasion and migration of brain macrophages in ischemic rat brain lesions.2013
- Author(s)
  Nari Tei
- Journal Title
  
  J. Neurosci. Res.
  
  Volume: 91 Pages: 681693-681693
- DOI
  10.1002/jnr.23202
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390037, KAKENHI-PROJECT-22591590, KAKENHI-PROJECT-23592092, KAKENHI-PROJECT-23592129, KAKENHI-PROJECT-23592130, KAKENHI-PROJECT-23659688, KAKENHI-PROJECT-24791507
[Journal Article] Expression of MCP-1 and fractalkine on endothelial cells and astrocytes may contribute to the invasion and migration of brain macrophages in ischemic rat brain lesions2013
- Author(s)
  Nari Tei, Junya Tanaka, Kana Sugimoto, Tasuku Nishihara, Ryutaro Nishioka, Hisaaki Takahashi, Hajime Yano, Shirabe Matsumoto, Shiro Ohue, Hideaki Watanabe, Yoshiaki Kumon, Takanori Ohnishi
- Journal Title
  
  J Neurosci Res
  
  Volume: 91 Pages: 681-693
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659688
[Journal Article] Expression of MCP-1 and fractalkine on endothelial cells and astrocytes may contribute to the invasion and migration of brain macrophages in ischemic rat brain lesions2013
- Author(s)
  Nari Tei, Junya Tanaka, Kana Sugimoto, Tasuku Nishihara, Ryutaro Nishioka, Hisaaki Takahashi, Hajime Yano, Shirabe Matsumoto, Shiro Ohue, Hideaki Watanabe, Yoshiaki Kumon, Takanori Ohnishi
- Journal Title
  
  J Neurosci Res
  
  Volume: 91 Pages: 681-693
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390037
[Journal Article] Expression of MCP-1 and Fractalkine on Endothelial Cells and Astrocytes May Contribute to the Invasion and Migration of Brain Macrophages in Ischemic Rat Brain Lesions2013
- Author(s)
  Nari Tei, Junya Tanaka, Kana Sugimoto, Tasuku Nishihara, Ryutaro Nishioka, Hisaaki Takahashi, Hajime Yano, Shirabe Matsumoto, Shiro Ohue, Hideaki Watanabe, Yoshiaki Kumon, Takanori Ohnishi
- Journal Title
  
  Journal of Neuroscience Research
  
  Volume: 91 Pages: 681-693
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791507
[Journal Article] Premetastatic vasculogenesis in oral squamous cell carcinoma xenograft-draining lymph nodes2012
- Author(s)
  Mayorca-Guiliani AE, Yano H, Nakashiro KI, Hamakawa H, Tanaka J
- Journal Title
  
  Oral Oncology
  
  Volume: 48 Pages: 663-670
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659688
[Journal Article] Zonisamide up-regulated them RNAs encoding astrocytic anti-oxidative and neurotrophic factors.2012
- Author(s)
  Choudhury ME, Sugimoto K, Kubo M, Iwaki H, Tsujii T, Kyaw WT, Nishikawa N, Nagai M, Tanaka J, Nomoto M
- Journal Title
  
  Eur J Pharmacol
  
  Volume: 689 Pages: 72-80
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659688
[Journal Article] Oct-3/4 promotes migration and invasion of glioblastoma cells.2012
- Author(s)
  Kobayashi K, Takahashi H, Inoue A, Harada H, Toshimori S, Kobayashi Y, Goto K, Sugimoto K, Yano H, Ohnishi T, Tanaka J.
- Journal Title
  
  J Cell Biochem
  
  Volume: 113 Pages: 508-517
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390037
[Journal Article] Premetastatic vasculogenesis in oral squamous cell carcinoma xenograft-draining lymph nodes.2012
- Author(s)
  Mayorca-Guiliani AE, Yano H, Nakashiro KI, Hamakawa H, Tanaka J.
- Journal Title
  
  Oral Oncology
  
  Volume: 48 Pages: 663-670
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390037
[Journal Article] Anticonvulsive effect of paeoniflorin on experimental febrile seizures in immature rats: possible application for febrile seizures in children.2012
- Author(s)
  Hino H, Takahashi H, Suzuki Y, Tanaka J, Ishii E, Fukuda M
- Journal Title
  
  PLoS ONE
  
  Volume: 7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591132
[Journal Article] Oct-3/4 promotes migration and invasion of glioblastoma cells2012
- Author(s)
  Kobayashi K, Takahashi H, Inoue A, Harada H, Toshimori S, Kobayashi Y, Goto K, Sugimoto K, Yano H, Ohnishi T, Tanaka J
- Journal Title
  
  J Cell Biochem
  
  Volume: 113 Pages: 508-517
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659688
[Journal Article] Zonisamide up-regulated them RNAs encoding astrocytic anti-oxidative and neurotrophic factors2012
- Author(s)
  Choudhury ME, Sugimoto K, Kubo M, Iwaki H, Tsujii T, Kyaw WT, Nishikawa N, Nagai M, Tanaka J, Nomoto M
- Journal Title
  
  Eur J Pharmacol
  
  Volume: 689 Pages: 72-80
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390037
[Journal Article] Anticonvulsive effect of paeoniflorin on experimental febrile seizures in immature rats: possible application for febrile seizures in children.2012
- Author(s)
  Hitomi Hino, Hisaaki Takahashi, Yuka Suzuki, Junya Tanaka, Eiichi Ishii, Mitsumasa Fukuda
- Journal Title
  
  PLoS One.
  
  Volume: 7
- DOI
  10.1371/journal.pone.0042920
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390037, KAKENHI-PROJECT-22591132, KAKENHI-PROJECT-23592129, KAKENHI-PROJECT-23659688
[Journal Article] Subcutaneous injection containing IL-3 and GM-CSF amelioratesstab wound-induced brain injury in rats2011
- Author(s)
  Nishihara T, Michihisa Ochi M, Kana Sugimoto K, Takahashi H, Yano H, Kumon Y, Ohnishi T, Tanaka J
- Journal Title
  
  Experimental Neurology
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390037
[Journal Article] Transient ischemia-induced paresis and complete paraplegia displayed distinct reactions of microglia and macrophages2011
- Author(s)
  NakataT, Kawachi K, Nagashima M, Yasugi T, Izutani H, Ryugo M, Okamura T, Shikata F, Imagawa H, Yano H, Takahashi H, Tanaka J
- Journal Title
  
  Brain Res
  
  Volume: 1420 Pages: 114-124
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659688
[Journal Article] Subcutaneous injection containing IL-3 and GM-CSF ameliorates stab wound-induced brain injury in rats. Tasuku2011
- Author(s)
  Hisaaki Takahashi, Hajime Yano, Yoshiaki Kumon, Takanori Ohnishi, Junya Tanaka.
- Journal Title
  
  Exp Neurol
  
  Volume: 229 Pages: 507-516
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390037
[Journal Article] Transient ischemia-induced paresis and complete paraplegia displayed distinct reactions of microglia and macrophages.2011
- Author(s)
  NakataT, Kawachi K, Nagashima M, Yasugi T, Izutani H, Ryugo M, Okamura T, Shikata F, Imagawa H, Yano H, Takahashi H, Tanaka J.
- Journal Title
  
  Brain Res
  
  Volume: 1420 Pages: 114-124
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390037
[Journal Article] Subcutaneous injection containing IL-3 and GM-CSF ameliorates stab wound-induced brain injury in rats2011
- Author(s)
  Nishihara, Michihisa Ochi, Kana Sugimoto, Hisaaki Takahashi, Hajime Yano, Yoshiaki Kumon, Takanori Ohnishi, Junya Tanaka
- Journal Title
  
  Exp Neurol
  
  Volume: 229 Pages: 507-516
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659688
[Journal Article] A cytokine mixture of GM‐CSF and IL‐3 that induces a neuroprotective phenotype of microglia leading to amelioration of (6‐OHDA)‐induced Parkinsonism of rats2011
- Author(s)
  Choudhury ME, Sugimoto K, Kubo M, Nagai M, Nomoto M, Takahashi H, Yano H, Tanaka J.
- Journal Title
  
  Brain Behav
  
  Volume: 1 Pages: 26-43
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390037
[Journal Article] A cytokine mixture of GM‐CSF and IL‐3 that induces a neuroprotective phenotype of microglia leading to amelioration of (6‐OHDA)‐induced Parkinsonism of rats2011
- Author(s)
  Choudhury ME, Sugimoto K, Kubo M, Nagai M, Nomoto M, Takahashi H, Yano H, Tanaka J
- Journal Title
  
  Brain Behav
  
  Volume: 1 Pages: 26-43
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659688
[Journal Article] Iba1(+)/NG2(+) macrophage-like cells expressing a variety of neuroprotective factors ameliorate ischemic damage of the brain2010
- Author(s)
  Smirkin, A.Matsumoto, H.Takahashi, H.Inoue, A.Tagawa, M.Ohue, S.Watanabe, H.Yano, H.Kumon, Y.Ohnishi, T.Tanaka, J.
- Journal Title
  
  Journal of Cerebral Blood Flow and Metabolism
  
  Volume: 30 Pages: 603-615
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390037
[Journal Article] Iba1+/NG2+ macrophage-like cells expressing a variety of neuroprotective factors ameliorate ischemic damage of the brain.2010
- Author(s)
  Anna Smirkin, Hiroaki Matsumoto, Hisaaki Takahashi, Akihiro Inoue, Masahiko Tagawa, Shiro Ohue, Hideaki Watanabe, Hajime Yano, Yoshiaki Kumon, Takanori Ohnishi and Junya TanakaJ
- Journal Title
  
  J Cereb Blood Flow Metab
  
  Volume: 30 Pages: 603-615
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390037
[Journal Article] Cancer stem-like cells of glioblastoma characteristically express MMP-13 and display highly invasive activity2010
- Author(s)
  Inoue A., Takahashi, H., Harada, H., Kohno, S., Ohue, S., Kobayashi, K., Yano, H., Tanaka, J., Ohnishi, T.
- Journal Title
  
  International journal of oncology
  
  Volume: 37 Pages: 1121-1131
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390037
[Journal Article] Cancer stem-like cells of glioblastoma characteristically express MMP-13 and display highly invasive activity.2010
- Author(s)
  Inoue, A., Takahashi, H., Harada, H., Kohno, S., Ohue, S., Kobayashi, K., Yano, H., Tanaka, J., Ohnishi, T.
- Journal Title
  
  Int J Oncol
  
  Volume: 37 Pages: 1121-1131
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390037
[Journal Article] Expression of CD200 by macrophage-like cells in ischemic core of rat brain after transient middle cerebral artery occlusion2007
- Author(s)
  H Matsumoto, Y Kumon, H Watanabe, T Ohnishi, H Takahashi, Y Imai, J Tanaka
- Journal Title
  
  Neuroscience Letters (In press)
- Data Source
  KAKENHI-PROJECT-17659448
[Journal Article] Antibodies to CD11b, CD68, and lectin label neutrophils rather than microglia in traumatic and ischemic brain lesions2007
- Author(s)
  H Matsumoto, Y Kumon, H Watanabe, T Ohnishi, M Shudou, C Ii, H Takahashi, Y Imai, J Tanaka
- Journal Title
  
  Journal of Neuroscience Research 85
  
  Pages: 994-1029
- Data Source
  KAKENHI-PROJECT-17659448
[Journal Article] Expression of heparanase in nestin-positive reactive astrocytes in ischemic lesions of rat brain after transient middle cerebral artery occlusion2007
- Author(s)
  H Takahashi, H Matsumoto, Y Kumon, T Ohnishi, C Freeman, Y Imai, J Tanaka
- Journal Title
  
  Neuroscience Letters (In press)
- Data Source
  KAKENHI-PROJECT-17659448
[Journal Article] Intravenous Infusion of Dihydroginsenoside Rbl Prevents Compressive Spinal Cord Injury and Ischemic Brain Damage through Upregulation of VEGF and Bcl-xL.2007
- Author(s)
  Sakanaka M, Zhu P, Zhang Bo, Wen TG, Cao F, Ma YJ, Samukawa K, Mitsuda N, Tanaka J, Kuramoto M, Uno H, Hata R.
- Journal Title
  
  Journal of Neurotrauma 24
  
  Pages: 1037-1054
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591594
[Journal Article] Intravenous Infusion of Dihydroginsenoside Rb 1 Prevents Compressive Spinal Cord Injury and Ischemic Brain Damage through Upregulation of VEGF and Bcl-xL2007
- Author(s)
  Sakanaka M, Zhu P, Zhang Bo, Wen TC, Cao F, Ma YJ, Samukawa K, Mitsuda N, Tanaka J, Kuramoto M, Uno H, Hata R.
- Journal Title
  
  Journal of Neurotrauma 24
  
  Pages: 1037-1054
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591594
[Journal Article] Intravenous Infusion of Dihydroginsenoside Rbl Prevents Compressive Spinal Cord Injury and Ischemic Brain Damage through Upregulation of VEGF and Bcl-xL2007
- Author(s)
  Sakanaka, M., Zhu, P., Zhang, Bo., Wen, TC., Cao, F., Ma, YJ., Samukawa, K., Mitsuda, N., Tanaka, J., Kuramoto, M., Uno, H., Hata, R
- Journal Title
  
  Journal of Neurotrauma 24
  
  Pages: 1037-1054
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591594
[Journal Article] NG2 proteoglycan-expressing microglia as multipotent neural progenitors in normal and pathologic brains2006
- Author(s)
  A Yokoyma, A Sakamoto, K Kameda, Y Imai, J Tanaka
- Journal Title
  
  Glia 53
  
  Pages: 754-768
- Data Source
  KAKENHI-PROJECT-17659448
[Journal Article] Overexpression of SOCS3 inhibits astrogliogenesis and promotes maintenance of neural stem cells2006
- Author(s)
  Cao, F., Hata, R., Zhu, P., Ma, Y.-J., Tanaka, J., Hanakawa, Y., Hashimoto, K., Niinobe M, Yoshikawa K, Sakanaka, M.
- Journal Title
  
  Journal of Neurochemistry 98
  
  Pages: 459-470
- Data Source
  KAKENHI-PROJECT-17659448
[Journal Article] NG2 proteoglycan-expressing microglia as multipotent neural progenitors in normal and pathologic brains2006
- Author(s)
  Yokoyma A, Sakamoto A, Kameda K, Imai Y, Tanaka J
- Journal Title
  
  Glia (in press)
- Data Source
  KAKENHI-PROJECT-16390442
[Journal Article] Overexpression of SOCS3 inhibits astrogliogenesis and promotes maintenance of neural stem cells2006
- Author(s)
  Cao, F., Hata, R., Zhu, P., Ma, YJ., Tanaka, J., Hanakawa, Y., Hashimoto, K., Niinobe, M., Yoshikawa, K., Sakanaka, M
- Journal Title
  
  J Neurochem 98
  
  Pages: 459-70
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591594
[Journal Article] Prevention of ischemic neuronal death by intravenous infusion of aginseng saponin,ginsenoside Rb(1),that upregulates Bcl-x(L)expression2006
- Author(s)
  Zhang B, Hata R, Zhu P, Sato K, Wen TC, Yang L, Fujita H, Mitsuda N, Tanaka J, Samukawa K, Maeda N, and Sakanaka M.
- Journal Title
  
  J Cereb Blood Flow Metab 26
  
  Pages: 708-721
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591594
[Journal Article] Overexpression of SOCS3 inhibits astrogliogenesis and promotes maintenance of neural stem cells.2006
- Author(s)
  Cao F, Hata R, Zhu P, Ma YJ, Tanaka J, Hanakawa Y, Hashimoto K, Niinobe M, Yoshikawa K, Sakanaka M.
- Journal Title
  
  J Neurochem. 98
  
  Pages: 459-70
- Data Source
  KAKENHI-PROJECT-18591594
[Journal Article] Prevention of ischemic neuronal death by intravenous infusion of a ginseng saponin, ginsenoside Rb(1), that upregulates Bcl-x(L) expression.2006
- Author(s)
  Zhang B, Hata R, Zhu P, Sato K, Wen TC, Yang L, Fujita H, Mitsuda N, Tanaka J, Samukawa K, Maeda N, Sakanaka M.
- Journal Title
  
  J Cereb Blood Flow Metab 26
  
  Pages: 708-721
- Data Source
  KAKENHI-PROJECT-18591594
[Journal Article] NG2 proteoglycan-expressing microglia as multipotent neural progenitors in normal and pathologic brains2006
- Author(s)
  Yokoyama A, Sakamoto A, Kameda K, Imai Y, Tanaka J
- Journal Title
  
  Glia 53
  
  Pages: 754-768
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390442
[Journal Article] Prevention of ischemic neuronal death by intravenous infusion of a ginseng saponin, ginsenoside Rb1, that upregulates Bcl-xL expression2006
- Author(s)
  Bo Zhang, Ryuji Hata, Pengxiang Zhu, Kohji Sato, Tong-Chun Wen, Lihua Yang, Hiroko Fujita, Noriaki Mitsuda, Junya Tanaka, Keiichi Samukawa, Nobuji Maeda, Masahiro Sakanaka
- Journal Title
  
  Journal of Cerebral Blood Flow & Metabolism 26
  
  Pages: 708-721
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390442
[Journal Article] Prevention of ischemic neuronal death by intravenous infusion of a ginseng saponin, ginsenoside Rb1, that upregulates Bcl-xL expression2006
- Author(s)
  Zhang B, Hata R, Zhu P, Sato K, Wen TC, Yang L, Fujita H, Mitsuda N, Tanaka J, Samukawa K, Maeda N, Sakanaka M
- Journal Title
  
  Journal of Cerebral Blood Flow & Metabolism (in press)
- Data Source
  KAKENHI-PROJECT-17659448
[Journal Article] Mapping a nucleolar targeting sequence of an RNA binding nucleolar protein, Nop252006
- Author(s)
  Fujiwara, T., Suzuki, S., Kanno, M., Sugiyama, H., Takahashi, H., Tanaka.J.
- Journal Title
  
  Experimental Cell Research 312
  
  Pages: 1703-1712
- Data Source
  KAKENHI-PROJECT-17659448
[Journal Article] NG2 proteoglycan-expressing microglia as multipotent neural progenitors in normal and pathologic brains2006
- Author(s)
  Yokoyma A, Sakamoto A, Kameda K, Imai Y, Tanaka J
- Journal Title
  
  Glia (in press)
- Data Source
  KAKENHI-PROJECT-17659448
[Journal Article] Prevention of ischemic neuronal death by intravenous infusion of a ginseng saponin,ginsenoside Rbl,that upregulates Bcl-xL expression2006
- Author(s)
  Zhang B, Hata R, Zhu P, Sato K, Wen TC, Yang L, Fujita H, Mitsuda N, Tanaka J, Samukawa K, Maeda N, Sakanaka M
- Journal Title
  
  Journal of Cerebral Blood Flow & Metabolism 26
  
  Pages: 708-721
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390442
[Journal Article] Prevention of ischemic neuronal death by intravenous infusion of a ginseng saponin, ginsenoside Rb1, that upregulates Bcl-xL expression2006
- Author(s)
  Zhang B, Hata R, Zhu P, Sato K, Wen TC, Yang L, Fujita H, Mitsuda N, Tanaka J, Samukawa K, Maeda N, Sakanaka M
- Journal Title
  
  Journal of Cerebral Blood Flow & Metabolism (in press)
- Data Source
  KAKENHI-PROJECT-16390442
[Journal Article] NG2 proteoglycan-expressing microglia as multipotent neural progenitors in normal and pathologic brains2006
- Author(s)
  Akiko Yokoyma, Aiko Sakamoto, Kenji Kameda, Yoshinori Imai, Junya Tanaka
- Journal Title
  
  Glia 53
  
  Pages: 754-768
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390442
[Journal Article] Prevention of ischemic neuronal death by intravenous infusion of a ginseng saponin, ginsenoside Rb(1), that upregulates Bcl-x(L) expression2006
- Author(s)
  Zhang, B., Hata, R., Zhu, P., Sato, K., Wen, TC., Yang, L., Fujita, H., Mitsuda, N., Tanaka, J., Samukawa, K., Maeda, N., Sakanaka, M
- Journal Title
  
  J Cereb Blood Flow Metab 26
  
  Pages: 708-721
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591594
[Journal Article] Prevention of ischemic neuronal death by intravenous infusion of a ginseng saponin, ginsenoside Rb1, that upregulates Bcl-xL expression2006
- Author(s)
  B Zhang, R Hata, P Zhu, K Sato, T-C Wen, L Yang, H Fujita, N Mitsuda, J Tanaka, K Samukawa, N Maeda, M Sakanaka
- Journal Title
  
  Journal of Cerebral Blood Flow ＆ Metabolism 26
  
  Pages: 708-721
- Data Source
  KAKENHI-PROJECT-17659448
[Journal Article] Molecular cloning and characterization of Nop25, a novel nucleolar RNA binding protein, highly conserved in vertebrate species2006
- Author(s)
  Suzuki, S., Kanno, M., Fujiwara, T., Sugiyama, H., Yokoyama, A., Takahashi, H., Tanaka, J.
- Journal Title
  
  Experimental Cell Research 312
  
  Pages: 1031-1041
- Data Source
  KAKENHI-PROJECT-17659448
[Journal Article] Overexpression of SOCS3 inhibits astrogliogenesis and promotes maintenance of neural stem cells2006
- Author(s)
  Cao F, Hata R, Zhu P, Ma YJ, Tanaka J, Hanakawa Y, Hashimoto K, Niinobe M, Yoshikawa K and Sakanaka M.
- Journal Title
  
  J Neurochem. 98
  
  Pages: 459-70
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591594
[Journal Article] Suppression of Stat3 promotes neurogenesis in cultured neural stem cells2005
- Author(s)
  Gu F, Hata R, Ma Yj, Tanaka J, Mitsuda N, Kumon Y, Hanakawa Y,, Hashimoto K, Nakajima K, Sakanaka M
- Journal Title
  
  Journal of Neuroscience Research 81
  
  Pages: 163-171
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390442
[Journal Article] Protein 4.1G localizes in rodent microglia2005
- Author(s)
  Nobuhiko Ohno, Nobuo Terada, Junya Tanaka, Akiko Yokoyama, Hisashi Yamakawa, Yasuhisa Fujii, Takeshi Baba, Osamu Ohara, Shinichi Ohno
- Journal Title
  
  Histochemistry and Cell Biology 124
  
  Pages: 477-486
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390442
[Journal Article] Suppression of Stat3 promotes neurogenesis in cultured neural stem cells2005
- Author(s)
  Feng Gu, Ryuji Hata, Yong-Jie Ma, Junya Tanaka, Noriaki Mitsuda, Yoshiaki Kumon, Yasushi Hanakawa, Koji Hashimoto, Koichi Nakajima, Masahiro Sakanaka
- Journal Title
  
  Journal of Neuroscience Research 81
  
  Pages: 163-171
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390442
[Journal Article] Suppression of Stat3 promotes neurogenesis in cultured neural stem cells2005
- Author(s)
  Gu F, Hata R, Ma YJ, Tanaka J, Mitsuda N, Kumon Y, Hanakawa Y, Hashimoto K, Nakajima K, Sakanaka M
- Journal Title
  
  Journal of Neuroscience Research 81
  
  Pages: 163-171
- Data Source
  KAKENHI-PROJECT-17659448
[Journal Article] Protein 4.1G localizes in rodent microglia2005
- Author(s)
  Ohno N, Terada N, Tanaka J, Yokoyama A, Yamakawa H, Fujii Y, Baba T, Ohara O, Ohno S
- Journal Title
  
  Histochemistry and Cell Biology 124
  
  Pages: 477-486
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390442
[Journal Article] Suppression of Stat3 promotes neurogenesis in cultured neural star cells.2005
- Author(s)
  Gu F, Hata R, Ma YJ, Tanaka J, Mitsuda N, Kumon Y, Hanakawa Y, Hashimoto K, Nakajima K, Sakanaka M.
- Journal Title
  
  J Neurosci Res. 86
  
  Pages: 163-171
- Data Source
  KAKENHI-PROJECT-16591444
[Journal Article] Suppression of Stat3 promotes neurogenesis in cultured neural stem cells.2005
- Author(s)
  Gu F, Hata R, Ma YJ, Tanaka J, Mitsuda N, Kumon Y, Hanakawa Y, Hashimoto K, Nakajima K, Sakanaka M.
- Journal Title
  
  Neurosci Res. 86
  
  Pages: 163-171
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591444
[Journal Article] Suppression of Stat3 promotes neurogenesis in cultured neural stem cells2005
- Author(s)
  Gu F, Hata R, Ma YJ, Tanaka J, Mitsuda N, Kumon Y, Hanakawa Y, Hashimoto K, Nakajima K, Sakanaka M
- Journal Title
  
  Journal of Neuroscience Research 81
  
  Pages: 163-171
- Data Source
  KAKENHI-PROJECT-16390442
[Journal Article] Protein 4.1G localizes in rodent microglia2005
- Author(s)
  Ohno N, Terada N, Tanaka J, Yokoyama A, Yamakawa H, Fujii Y,. Baba T, Ohara O, Ohno S
- Journal Title
  
  Histochemistry and Cell Biology 124
  
  Pages: 477-486
- Data Source
  KAKENHI-PROJECT-17659448
[Journal Article] suppression of Stat3 promotes neurogenesis in cultured neural stem cells.2005
- Author(s)
  Gu F, Hata R, Ma YJ, Tanaka J, Mitsuda N, Kumo Y, Hanakawa Y, Hashimoto K, Nakajima K, Sakanaka M
- Journal Title
  
  J Neurosci Res. 86
  
  Pages: 163-171
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591444
[Journal Article] L-Serine-mediated release of apolipoprotein E and lipids from microglial cells.2004
- Author(s)
  Kohji Mori, Akiko Yokoyama, Lihua Yang, Limin Yang, Nobuji Maeda, Noriaki Mitsuda, Junya Tanaka
- Journal Title
  
  Experimental Neurology 185
  
  Pages: 220-231
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390442
[Journal Article] Microglia, a potential source of neurons, astrocytes, and oligodendrocytes.2004
- Author(s)
  Yokoyama A, Yang L, Itoh S, Mori K, Tanaka J
- Journal Title
  
  Glia 45
  
  Pages: 96-104
- Data Source
  KAKENHI-PROJECT-15659356
[Journal Article] Protective effect of vitamin E against focal brain ischemia and neuronal death through induction of target genes of hypoxia-inducible factor-1.2004
- Author(s)
  Zhang, B., Tanaka, J., Yang, L., Yang, L., Sakanaka, M., Hata, R., Maeda, N., Mitsuda, N.
- Journal Title
  
  Neuroscience 126
  
  Pages: 433-440
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390442
[Journal Article] Protective effect of vitamin B against focal brain ischemia and neuronal death through induction of target genes of hypoxia-inducible factor-1.2004
- Author(s)
  Zhang, B., Tanaka, J., Yang, L., Yang, L., Sakanaka, M., Hata, R., Maeda, N., Mitsuda, N.
- Journal Title
  
  Neuroscience 126
  
  Pages: 433-440
- Data Source
  KAKENHI-PROJECT-15659356
[Journal Article] Protective effect of vitamin E against focal brain ischemia and neuronal death through induction of target genes of hypoxia-inducible factor-12004
- Author(s)
  Zhang, B., Tanaka J., Yang L., Sakanaka M., Hata R., Maeda N., Mitsuda N
- Journal Title
  
  Neuroscience 126
  
  Pages: 433-440
- Data Source
  KAKENHI-PROJECT-16591444
[Journal Article] Microglia, a potential source of neurons, astrocytes, and oligodendrocytes.2004
- Author(s)
  Akiko Yokoyama, Lihua Yang, Suzuka Itoh, Kohji Mori, Junya Tanaka
- Journal Title
  
  Glia 45
  
  Pages: 96-104
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390442
[Journal Article] Protective effect of vitamin E against focal brain ischemia and neuronal death through induction of target genes of hypoxia-inducible factor-12004
- Author(s)
  Zhang, B., Tanaka J., Yang L., Sakanaka M., Hata R., bMaeda N., Mitsuda N.
- Journal Title
  
  Neuroscience 126
  
  Pages: 433-440
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591444
[Journal Article] L-Serine-mediated release of apolipoprotein E and lipids from microglial cells.2004
- Author(s)
  Mori K, Yokoyama A, Yang L, Yang L, Maeda N, Mitsuda N, Tanaka J
- Journal Title
  
  Experimental Neurology 185
  
  Pages: 220-231
- Data Source
  KAKENHI-PROJECT-16390442
[Journal Article] L-Serine-mediated release of apolipoprotein E and lipids from microglial cells.2004
- Author(s)
  Mori K, Yokoyama A, Yang L, Maeda N, Mitsda N, Tanaka J
- Journal Title
  
  Experimental Neurology 185
  
  Pages: 220-231
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390442
[Journal Article] L-Serine-mediated release of apolipoprotein E and lipids from microglial cells.2004
- Author(s)
  Mori K, Yokoyama A, Yang L, Yang L, Maeda N, Mitsuda N, Tanaka J
- Journal Title
  
  Experimental Neurology 185
  
  Pages: 220-231
- Data Source
  KAKENHI-PROJECT-15659356
[Journal Article] Microglia, a potential source of neurons, astrocytes, and oligodendrocytes.2004
- Author(s)
  Yokoyama A, Yang L, Itoh S, Mori K, Tanaka J
- Journal Title
  
  Glia 45
  
  Pages: 96-104
- Data Source
  KAKENHI-PROJECT-16390442
[Journal Article] Protective effect of vitamin E against focal brain ischemia and neuronal death through induction of target genes of hypoxia-inducible factor-12004
- Author(s)
  Zhang, B., Tanaka J., Yang L., Sakanaka M., Hata R., Maeda N., Mitsuda N.
- Journal Title
  
  Neuroscience 126
  
  Pages: 433-40
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591444
[Journal Article] Protective effect of vitamin E against focal brain ischemia and neuronal death through induction of target genes of hypoxia-inducible factor-l.2004
- Author(s)
  Zhang, B., Tanaka, J., Yang, L., Sakanaka, M., Hata, R., Maeda, N, Mitsuda, N
- Journal Title
  
  Neuroscience 126
  
  Pages: 433-440
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390442
[Journal Article] Microglia, a potential source of neurons, astrocytes, and oligodendrocytes.2004
- Author(s)
  Yokoyama A, Yang L, Itho S, Mori K, Tanaka J
- Journal Title
  
  Glia 45
  
  Pages: 96-104
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390442
[Journal Article] Prevention of ischemic neuronal death by intravenous infusion of a ginseng saponin, ginsenoside Rb(1), that upregulates Bcl-x(L) expression.
- Author(s)
  Zhang B, Hata R, Zhu P, Sato K, Wen TC, Yan L, Fujita H, Mitsuda N, Tanaka J, Samukawa K, Maeda N, Sakanaka M
- Journal Title
  
  J Cereb Blood Flow Metab (In press)
- Data Source
  KAKENHI-PROJECT-16591444
[Patent] 免疫細胞の活性化抑制剤およびその用途2012
- Inventor(s)
  田中潤也
- Industrial Property Rights Holder
  国立大学法人愛媛大学
- Industrial Property Number
  2012-173405
- Filing Date
  2012-08-03
- Data Source
  KAKENHI-PROJECT-22390037
[Patent] 免疫細胞の活性化抑制剤およびその用途2012
- Inventor(s)
  田中潤也
- Industrial Property Rights Holder
  国立大学法人愛媛大学
- Industrial Property Number
  2012-173405
- Filing Date
  2012-08-03
- Data Source
  KAKENHI-PROJECT-23659688
[Presentation] Oct-3/4を介したMGMT遺伝子発現調節とDNMT1の関連性2017
- Author(s)
  井上明宏、高野昌平、大上史朗、高橋寿明、田中潤也、大西丘倫、國枝武治
- Organizer
  第35回　日本脳腫瘍病理学会
- Data Source
  KAKENHI-PROJECT-15K10324
[Presentation] Expression of oxytocin receptor in ischemic lesions of rat brain: one protective mechanism of oxytocin for injured neurons2017
- Author(s)
  Kana Sugimoto, Yuki Mori, Hidekazu Tanaka, Yuichiro Hirata, Yu Kamakura, Makiko Takahashi, Ryuichi Katada, Hiroshi Matsumoto
- Organizer
  第94回日本生理学会大会
- Place of Presentation
  アクトシティ浜松（浜松）
- Year and Date
  2017-03-28
- Data Source
  KAKENHI-PROJECT-26861150
[Presentation] 膠芽腫におけるOct-3/4を介したMGMT遺伝子発現調節とDNMT1の関連性2017
- Author(s)
  井上明宏、高野昌平、西川真弘、末廣諭、高橋寿明、田中潤也、國枝武治
- Organizer
  日本脳神経外科学会第76回学術総会
- Data Source
  KAKENHI-PROJECT-15K10324
[Presentation] マイクログリアのラット脳におけるサーカディアンリズム：形態学的検討2016
- Author(s)
  武田遙奈、宮西和也、EM チョードリ、金久浩大、矢野元、田中潤也
- Organizer
  第93回日本生理学会大会
- Place of Presentation
  北海道札幌市
- Year and Date
  2016-03-22
- Data Source
  KAKENHI-PROJECT-15K14351
[Presentation] 膠芽腫におけるMGMT発現調節機構に対するOct-3/4を介したエピジェネティクスの制御2016
- Author(s)
  井上明宏、大上史朗、岩田真治、河野兼久、高野昌平、大西丘倫、高橋寿明、田中潤也
- Organizer
  日本脳神経外科学会第75回学術総会
- Place of Presentation
  福岡
- Year and Date
  2016-09-29
- Data Source
  KAKENHI-PROJECT-15K10324
[Presentation] Oct-3/4のMGMT発現調節機構への関与2016
- Author(s)
  井上明宏、高野昌平、大上史朗、大西丘倫、高橋寿明、田中潤也
- Organizer
  第34回日本脳腫瘍病理学会
- Place of Presentation
  東京
- Year and Date
  2016-05-27
- Data Source
  KAKENHI-PROJECT-15K10324
[Presentation] ラット脳におけるイオンチャネルの発現量に及ぼすエタノールの影響2016
- Author(s)
  杉本香奈，片田竜一，田中秀和，平田雄一郎，鎌倉悠宇，吉田原規，高橋真樹子, 望月薫，五十嵐一雄，松本博志
- Organizer
  第100次日本法医学会学術全国集会
- Place of Presentation
  きゅりあん（東京）
- Year and Date
  2016-06-15
- Data Source
  KAKENHI-PROJECT-26861150
[Presentation] Expression of oxytocin receptors in the peri-infarct tissue of rat brain: protection of oxytocin for injured neurons2016
- Author(s)
  Kana Sugimoto, Yuki Mori, Hidekazu Tanaka, Yuichiro Hirata, Yu Kamakura, Ryuichi Katada, Hiroshi Matsumoto
- Organizer
  第39回日本神経科学大会
- Place of Presentation
  パシフィコ横浜（横浜）
- Year and Date
  2016-07-20
- Data Source
  KAKENHI-PROJECT-26861150
[Presentation] High mobility group box 1 after infantile experimental prolonged febrile seizures enhances acquired epileptogenesis in adulthood2015
- Author(s)
  Ito M, Fukuda M, Yano H, Yano Y, Tanaka J, Ishii E
- Organizer
  第49回日本てんかん学会学術集会
- Place of Presentation
  長崎県長崎市
- Year and Date
  2015-10-30
- Data Source
  KAKENHI-PROJECT-25461553
[Presentation] 睡眠―覚醒リズムへのマイクログリア関与の可能性：青斑核ノルアドレナリンとの関連2015
- Author(s)
  宮西和也、EM チョードリ、金久浩大、武田遥奈、矢野元、田中潤也
- Organizer
  第25回　日本病態生理学会大会
- Place of Presentation
  愛媛県松山市
- Year and Date
  2015-08-02
- Data Source
  KAKENHI-PROJECT-15K14351
[Presentation] Effects of ethanol and psychotropic drugs on the signal transcription in the rat brain2014
- Author(s)
  Kana Sugimoto, Hidekazu Tanaka, Kazuo Igarashi, Motonori Yoshida, Ryuichi Katada, Hiroshi Matsumoto
- Organizer
  9th International Symposium on Advances in Legal Medicine
- Place of Presentation
  福岡国際会議場（福岡）
- Year and Date
  2014-06-18
- Data Source
  KAKENHI-PROJECT-26861150
[Presentation] Treadmill exercise as rehabilitation for stroke model; its effects through increased serum corticosterone level2014
- Author(s)
  Nishioka Ryutaro, Sugimoto Kana, Mise Ayano, Kojyo Katsura, Mohammed E Choudhury, Takahashi Hisaaki, Yano Hajime, Tanaka Junya
- Organizer
  第91回　日本生理学会
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-24791507
[Presentation] Response of glial cells to IL18 produced in the ischemic rat brains2014
- Author(s)
  Ayano Mise, Kana Sugimoto, Ryutaro Nishioka, Hisaaki Takahashi, Hajime Yano, Junya Tanaka
- Organizer
  第91回日本生理学
- Data Source
  KAKENHI-PROJECT-24791507
[Presentation] The light treadmill exercise after the cerebral infarction controls cellular edema: the involvement of aquaporin 4 and sodium/hydrogen exchanger 12014
- Author(s)
  Kojyo Katsura, Nishioka Ryutaro, Sugimoto Kana, Aono Hitomi, Mohammed E Choudhury, Takahashi Hisaaki, Yano Hajime, Tanaka Junya
- Organizer
  第91回　日本生理学会
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-24791507
[Presentation] The light treadmill exercise after the cerebral infarction controls cellular edema : the involvement of aquaporin 4 and sodium/ hydrogen exchanger12014
- Author(s)
  Katsura Kojyo, Ryutaro Nishioka, Kana Sugimoto, Hitomi Aono, Choudhury E Mohammed, Hisaaki Takahashi, Hajime Yano, Junya Tanaka
- Organizer
  第91回日本生理学
- Data Source
  KAKENHI-PROJECT-24791507
[Presentation] Treadmill exercise as rehabilitation for stroke model; its effects through increased serum corticosterone level2014
- Author(s)
  Ryutaro Nishioka, Kana Sugimoto, Ayano Mise, Katsura Kojyo, Choudhury E Mohammed, Hisaaki Takahashi, Hajime Yano, Junya Tanaka
- Organizer
  第91回日本生理学
- Data Source
  KAKENHI-PROJECT-24791507
[Presentation] Response of glial cells to IL18 produced in the ischemic rat brains2014
- Author(s)
  Mise Ayano, Sugimoto Kana, Nishioka Ryutaro, Takahashi Hisaaki, Yano Hajime, Tanaka Junya
- Organizer
  第91回　日本生理学会
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-24791507
[Presentation] Agents modulating neuroprotective and neurotoxic functions of microglia and their application to the pathologic brains2013
- Author(s)
  Junya Tanaka
- Organizer
  第90回日本生理学会大会
- Place of Presentation
  東京都
- Data Source
  KAKENHI-PROJECT-23659688
[Presentation] Treadmill exercise as rehabilitation for stroke model; its effects on brain edema and glial reactions2013
- Author(s)
  Ryutaro Nishioka, Kana Sugimoto, Ayano Mise, Hisaaki Takahashi, Hajime Yano, Junya Tanaka
- Organizer
  第90回日本生理学会大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24791507
[Presentation] ラット実験的脳梗塞巣におけるTGF-β1および IL-18 の発現とその病態生理学的意義2013
- Author(s)
  三瀬綾乃、杉本香奈、西岡龍太郎、高橋寿明、矢野元、久門良明、大西丘倫、田中潤也
- Organizer
  第65 回　日本生理学会中国四国地方会
- Place of Presentation
  川崎医科大学
- Data Source
  KAKENHI-PROJECT-24791507
[Presentation] 脳梗塞巣周辺領域に存在するNG2陽性マイクログリアの意義2013
- Author(s)
  杉本香奈、田中潤也、片田竜一、松本博志
- Organizer
  第60回　日本法医学会　学術近畿地方集会
- Place of Presentation
  近畿大学
- Data Source
  KAKENHI-PROJECT-24791507
[Presentation] Effects of TGFβ1 on microglia in the penumbra of ischemic rat brain2013
- Author(s)
  Kana Sugimoto, Ryutaro Nishioka, Ayano Mise, Yudai Oohara, Kohei Shiota, Hisaaki Takahashi, Hajime Yano, Junya Tanaka
- Organizer
  第90回日本生理学会大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24791507
[Presentation] 実験的ラット脳梗塞に対する急性期運動療法の浮腫抑制効果 : 副腎皮質ステロイドの関与2013
- Author(s)
  西岡龍太郎, 杉本香奈, 三瀬綾乃, 湖城桂, 青野仁美, 高橋寿明, 矢野元, 田中潤也
- Organizer
  第65回日本生理学会中国四国地方会
- Data Source
  KAKENHI-PROJECT-24791507
[Presentation] 実験的ラット脳梗塞に対する急性期運動療法の浮腫抑制効果:副腎皮質ステロイドの関与2013
- Author(s)
  西岡龍太郎、杉本香奈、三瀬綾乃、湖城桂、青野仁美、高橋寿明、矢野元、田中潤也
- Organizer
  第65 回　日本生理学会中国四国地方会
- Place of Presentation
  川崎医科大学
- Data Source
  KAKENHI-PROJECT-24791507
[Presentation] Invasion of monocytes/macrophages into ischemic lesion of rat brain: involvement of chemokines and their receptors2013
- Author(s)
  Yudai Ohara, Kana Sugimoto, Ryutaro Nishioka, Hisaaki Takahashi, Hajime Yano、Nari Tei, Yoshiaki Kumon, Takanori Ohnishi, Junya Tanaka
- Organizer
  第90回日本生理学会大会
- Place of Presentation
  東京都
- Data Source
  KAKENHI-PROJECT-22390037
[Presentation] ラット実験的脳梗塞巣におけるTGF-β1 およびIL-18 の発現とその病態生理学的意義2013
- Author(s)
  三瀬綾乃, 杉本香奈, 西岡龍太郎, 高橋寿明, 矢野元, 久門良明, 大西丘倫, 田中潤也
- Organizer
  第65回日本生理学会中国四国地方会
- Data Source
  KAKENHI-PROJECT-24791507
[Presentation] Treadmill exercise as rehabilitation for stroke model; its effects on brain edema and glial reactions2013
- Author(s)
  Ryutaro Nishioka, Kana Sugimoto, Ayano Mise, Hisaaki Takahashi, Hajime Yano, Junya Tanaka
- Organizer
  第90回日本生理学
- Data Source
  KAKENHI-PROJECT-24791507
[Presentation] Invasion of monocytes/macrophages into ischemic lesion of rat brain: involvement of chemokines and their receptors2013
- Author(s)
  Yudai Ohara, Kana Sugimoto, Ryutaro Nishioka, Hisaaki Takahashi, Hajime Yano and Nari Tei, Yoshiaki Kumon, Takanori Ohnishi, Junya Tanaka
- Organizer
  第90回日本生理学会大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24791507
[Presentation] Agents modulating neuroprotective and neurotoxic functions of microglia and their application to the pathologic brains2013
- Author(s)
  Junya Tanaka
- Organizer
  第90回日本生理学会大会
- Place of Presentation
  東京
- Invited
- Data Source
  KAKENHI-PROJECT-22390037
[Presentation] Agents modulating neuroprotective and neurotoxic functions of microglia and their application to the pathologic brains2013
- Author(s)
  Junya Tanaka
- Organizer
  第90回日本生理学会大会
- Place of Presentation
  東京
- Invited
- Data Source
  KAKENHI-PROJECT-23659688
[Presentation] Response of glial cells in and around ischemic lesion of rats that were subjected to transient middle cerebral artery occlusion: the involvement of IL-182013
- Author(s)
  Ayano Mise, Kana Sugimoto, Ryutaro Nishioka, Hisaaki Takahashi, Hajime Yano, Junya Tanaka
- Organizer
  第90回日本生理学会大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24791507
[Presentation] Invasion of monocytes/macrophages into ischemic lesion of rat brain: involvement of chemokines and their receptors2013
- Author(s)
  Yudai Ohara, Kana Sugimoto, Ryutaro Nishioka, Hisaaki Takahashi, Hajime Yano、Nari Tei, Yoshiaki Kumon, Takanori Ohnishi, Junya Tanaka
- Organizer
  第90回日本生理学会大会
- Place of Presentation
  東京都
- Data Source
  KAKENHI-PROJECT-23659688
[Presentation] Response of glial cells in and around ischemic lesion of rats that were subjected to transient middle cerebral artery occlusion: the involvement of IL-182013
- Author(s)
  Ayano Mise, Kana Sugimoto, Ryutaro Nishioka, Hisaaki Takahashi, Hajime Yano, Junya Tanaka
- Organizer
  第90回日本生理学会大会
- Place of Presentation
  東京都
- Data Source
  KAKENHI-PROJECT-23659688
[Presentation] Invasion of monocytes/macrophages into the ischemic lesion of rat brain : involvement of chemokines and their receptors2013
- Author(s)
  Yudai Ohara, Kana Sugimoto, Ryutaro Nishioka, Hisaaki Takahashi, Hajime Yano, Junya Tanaka
- Organizer
  第90回日本生理学
- Data Source
  KAKENHI-PROJECT-24791507
[Presentation] 脳梗塞巣周辺領域に存在するNG2 陽性マイクログリアの意義2013
- Author(s)
  杉本香奈, 田中潤也, 片田竜一, 松本博志
- Organizer
  第60回日本法医学会学術近畿地方集会
- Data Source
  KAKENHI-PROJECT-24791507
[Presentation] Effects of TGF-β1 on microglia in the penumbra of ischemic rat brain2013
- Author(s)
  Kana Sugimoto, Ryutaro Nishioka, Ayano Mise, Yudai Ohara, Kohei Shiota, Hisaaki Takahashi, Hajime Yano, Junya Tanaka
- Organizer
  第90回日本生理学
- Data Source
  KAKENHI-PROJECT-24791507
[Presentation] Response of glial cells in and around ischemic lesion of rats that were subjected to transient middle cerebral artery occlusion : the involvement of IL-182013
- Author(s)
  Ayano Mise, Kana Sugimoto, Ryutaro Nishioka, Hisaaki Takahashi, Hajime Yano, Junya Tanaka
- Organizer
  第90回日本生理学
- Data Source
  KAKENHI-PROJECT-24791507
[Presentation] 脳梗塞モデルラットに対するトレッドミル運動の予後改善効果と脳梗塞巣におけるグリア細胞の反応について2012
- Author(s)
  西岡龍太郎、杉本香奈、高橋寿明、矢野元、田中潤也
- Organizer
  第64回日本生理学会中国四国地方会
- Place of Presentation
  高知
- Data Source
  KAKENHI-PROJECT-24791507
[Presentation] 脳梗塞巣核心部のマクロファージと周辺グリア細胞相互作用2012
- Author(s)
  三瀬綾乃、西岡龍太郎、杉本香奈、高橋寿明、矢野元、田中潤也
- Organizer
  第64回日本生理学会中国四国地方会
- Place of Presentation
  高知
- Data Source
  KAKENHI-PROJECT-24791507
[Presentation] 脳梗塞巣核心部のマクロファージと周辺グリア細胞の相互作用2012
- Author(s)
  三瀬綾乃, 西岡龍太郎, 杉本香奈, 高橋寿明, 矢野元, 田中潤也
- Organizer
  第64回日本生理学会中国四国地方会
- Data Source
  KAKENHI-PROJECT-24791507
[Presentation] A cytokine mixture containing GM-CSF and IL-3 targeting microglia ameliorates neurological deficits of Parkinson's disease model rats2012
- Author(s)
  Junya Tanaka, Mohammed E. Choudhury, Kana Sugimoto, Hisaaki Takahashi, Hajime Yano
- Organizer
  第89回日本生理学会大会
- Place of Presentation
  松本市
- Data Source
  KAKENHI-PROJECT-22390037
[Presentation] Paeoniflorin suppresses experimental febrile seizures and inhibits glutamate-mediated neuronal excitability and neuronal death.2012
- Author(s)
  Hino H, Takahashi H, Suzuki Y, Kikuchi C, Tanaka J, Ishii E, Fukuda M.
- Organizer
  12th International Child Neurology Congress - 11th Asian and Oceanian Congress of Child Neurology
- Place of Presentation
  Brisbane, Australia
- Year and Date
  2012-06-01
- Data Source
  KAKENHI-PROJECT-22591132
[Presentation] 脳梗塞巣に集積するマクロファージの役割とその治療的利用2012
- Author(s)
  田中潤也、杉本香奈、西原佑、高橋寿明、矢野元
- Organizer
  第22回日本病態生理学会
- Place of Presentation
  大分県由布市
- Data Source
  KAKENHI-PROJECT-23659688
[Presentation] Paeoniflorin suppresses experimental febrile seizures and inhibits glutamate-mediated neuronal excitability and neuronal death.2012
- Author(s)
  Hino H, Takahashi H, Suzuki Y, Kikuchi C, Tanaka J, Ishii E, Fukuda M.
- Organizer
  12th International Child Neurology Congress - 11th Asian and Oceanian Congress of Child Neurology.
- Place of Presentation
  Brisbane, Australia
- Data Source
  KAKENHI-PROJECT-22591132
[Presentation] 脳梗塞モデルラットに対するトレッドミル運動の予後改善効果と脳梗塞巣におけるグリア細胞の反応について2012
- Author(s)
  西岡龍太郎, 杉本香奈, 高橋寿明, 矢野元, 田中潤也
- Organizer
  第64回日本生理学会中国四国地方会
- Data Source
  KAKENHI-PROJECT-24791507
[Presentation] 脳梗塞巣に集積するマクロファージの役割とその治療的利用2012
- Author(s)
  田中潤也、杉本香奈、西原佑、高橋寿明、矢野元
- Organizer
  第22回日本病態生理学会
- Place of Presentation
  大分県由布市
- Data Source
  KAKENHI-PROJECT-22390037
[Presentation] A cytokine mixture containing GM-CSF and IL-3 targeting microglia ameliorates neurological deficits of Parkinson's disease model rats2012
- Author(s)
  Junya Tanaka, Mohammed E. Choudhury, Kana Sugimoto, Hisaaki Takahashi, Hajime Yano
- Organizer
  第89回日本生理学会大会
- Place of Presentation
  大分県由布市
- Data Source
  KAKENHI-PROJECT-23659688
[Presentation] 神経細胞傷害に対するグリア細胞の反応：ラット6-OHDA負荷パーキンソン病モデルを用いた検討2011
- Author(s)
  田中潤也　他
- Organizer
  第21回日本病態生理学会大会
- Place of Presentation
  東京都板橋区
- Data Source
  KAKENHI-PROJECT-23659688
[Presentation] 神経細胞傷害に対するグリア細胞の反応:ラット6-OHDA負荷パーキンソン病モデルを用いた検討2011
- Author(s)
  田中潤也, 他
- Organizer
  第21回日本病態生理学会大会
- Place of Presentation
  東京都板橋区
- Year and Date
  2011-08-20
- Data Source
  KAKENHI-PROJECT-22390037
[Presentation] A new therapeutic approach for severe brain damages utilizing Iba1+/NG2+ macrophage-like cells expressing a variety of neuroprotective factors2010
- Author(s)
  田中潤也, 他
- Organizer
  日本生理学会
- Place of Presentation
  盛岡市
- Year and Date
  2010-05-21
- Data Source
  KAKENHI-PROJECT-21659341
[Presentation] Generation of ramified microglia and other types of neural cells from leptomeninges2010
- Author(s)
  Kana Sugimoto, Hisaaki Takahashi, Hajime Yano, Junya Tanaka
- Organizer
  Neuro2010
- Place of Presentation
  神戸
- Year and Date
  2010-09-02
- Data Source
  KAKENHI-PROJECT-22390037
[Presentation] Macrophages expressing NG2 proteoglycan in the ischemic and traumatic rat brain lesions elicit neuroprotective effects through multiple ways2009
- Author(s)
  田中潤也, 他
- Organizer
  国際生理学会
- Place of Presentation
  京都市
- Year and Date
  2009-07-28
- Data Source
  KAKENHI-PROJECT-21659341
[Presentation] Ethanol-induced expression of ion channels in rat brain slices
- Author(s)
  Kana Sugimoto, Hidekazu Tanaka, Ryuichi Katada, Motonori Yoshida, Kazuo Igarashi, Hiroshi Matsumoto
- Organizer
  16th International Society of Addiction Medicine Annual Meeting
- Place of Presentation
  パシフィコ横浜（横浜）
- Year and Date
  2014-10-02 – 2014-10-06
- Data Source
  KAKENHI-PROJECT-26861150
[Presentation] Transcriptome analysis on ethanol-induced brain injury among primary cultures of brain cells and slices
- Author(s)
  Kana Sugimoto, Hidekazu Tanaka, Ryuichi Katada, Kazuo Igarashi, Motonori Yoshida, Hiroshi Matsumoto
- Organizer
  Neuroscience 2014
- Place of Presentation
  Washington (USA)
- Year and Date
  2014-11-15 – 2014-11-19
- Data Source
  KAKENHI-PROJECT-26861150
[Presentation] エタノールと向精神薬のラット脳の転写シグナルに及ぼす影響
- Author(s)
  杉本香奈、片田竜一、田中秀和、吉田原規、佐藤崇裕、中間健太郎、吉澤秀憲、五十嵐一雄、松本博志
- Organizer
  平成26年度　アルコール・薬物依存関連学会合同学術総会
- Place of Presentation
  パシフィコ横浜（横浜）
- Year and Date
  2014-10-03 – 2014-10-04
- Data Source
  KAKENHI-PROJECT-26861150
[Presentation] Role of brain cell components in ethanol-induced signal transcription in the brain
- Author(s)
  Kana Sugimoto, Ryuichi Katada, Hidekazu Tanaka, Kazuo Igarashi, Motonori Yoshida, Hiroshi Matsumoto
- Organizer
  Neuroscience 2014
- Place of Presentation
  パシフィコ横浜（横浜）
- Year and Date
  2014-09-11 – 2014-09-13
- Data Source
  KAKENHI-PROJECT-26861150

1. SOBUE Kenji (20112047)

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TANAKA Junya 田中 潤也

田中 潤也 タナカ ジユンヤ

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Heterosexual communication and microglial synaptic pruningPrincipal Investigator

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Involvement of microglial cells in the sleep/wake cyclePrincipal Investigator

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Determination of cell type(s) that should be transplanted into lesion core of the brain for better outcomePrincipal Investigator

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Multipotential stem cell-like nature of bone marrow-derived macrophages accumulated in lesion core of acute and severe brain injuries.Principal Investigator

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神経膠腫細胞浸潤におけるArf6依存性および非依存性の意義Principal Investigator

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トランスジェニックマウスを用いたマイクログリアによる脳損傷修復システムの解明Principal Investigator

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TANAKA Junya 田中潤也

田中潤也タナカジユンヤ