NEGORO Takaharu 根来孝治

Researcher Number	70218270
Other IDs
Affiliation (based on the past Project Information) *help	2017: 帝京平成大学, 薬学部, 講師 2016 – 2017: 帝京平成大学, 薬学部, 教授 2009 – 2015: Showa University, 薬学部, 講師 2013: 昭和大学, 薬学部、薬学研究科, 講師 2011: 昭和大学, 薬学部, 准教授 2003 – 2005: 昭和大学, 薬学部, 助手
Review Section/Research Field	Principal Investigator 膠原病・アレルギー・感染症内科学 / Collagenous pathology/Allergology Except Principal Investigator Experimental pathology / Biological pharmacy / Pharmacology in pharmacy / Medical pharmacy / 膠原病・アレルギー・感染症内科学 / Respiratory organ internal medicine
Keywords	Principal Investigator 制御性T細胞 / カルシウム / カルシウム応答性 / FOXP3 splicing variants / 制御性Ｔ細胞 / アレルギー・ぜんそく / 気管支喘息 / 調節性T細胞 / FOXP3スプライスバリアント / イギリス：スペイン：アメリカ … More / CRACチャネル / 免疫抑制 / カルシウムイオン / カルシウムチャネル / アレルギー疾患 / イギリス：スペイン / 国際情報交換 / ERK / ペルオキシレドキシン / 酸化ストレス / RACK1 / adiponectin Tgマウス / 肥満 / Th17 / 抗炎症 / 関節リウマチ / adiponectin / B細胞 / adiponectin Tg mouse / 炎症性サイトカイン / 酸応答性チャネル / マクロファージ / 炎症 / アディポネクチン / 炎症学 … More Except Principal Investigator TRPM2 / マクロファージ / アディポネクチン / 炎症 / 活性酸素 / anergy / 生活習慣病 / ＴＲＰＭ２ / 低アディポネクチン血症 / 易炎症性 / 高分子量アディポネクチン / 心臓 / 心臓機能 / ADP-ribose / マウス / 心拍数 / 虚血再灌流 / 不整脈 / 心機能 / TRPM2チャネル / obesity / adipocyte / inflammation / coronary artery disease / diabetes mellitus / gelatin-binding / HMW (high-molecular weight) / adiponectin / HMW(high-modecular weight) / 肥満 / 脂肪細胞 / 冠動脈疾患 / 糖尿病 / ゼラチン結合性 / HMV(high-molecular weight) / Ca^<2+> responses / asthma / CD25^<high>CD4+Tregs / CD25^<high>Treg / 不応答(anergy) / アレルギー反応 / 喘息 / Ca流入 / Treg / CD25^<high>CD4^+CD45RO^+T細胞 / Ca^<2+>不応答性 / CD45RO^+ T細胞 / CD25^<high>CD4^+ T細胞 / Tregs / regulatory T cells / 制御性T細胞 / 低アディポネクチン血漿 / アディポネクチントランスジェニックマウス / 未病状態 / ケモカイン / 腫瘍関連マクロファージ / 悪性腫瘍 / 腫瘍 / TRPM2 チャネル / 血管新生 / サイトカイン / カルシウムイオン / 固形がん / エピジェネティクス / エピジェティクス / 虚血-再灌流障害 / Ca2+透過性チャネル / 好中球 / カルシムイオン / 虚血再灌流障害 / Ca^<2+> / Th2細胞 / Th1細胞 / 単球 / 酸化ストレス / 過酸化水素 / カルシウムイン / 単核球 / 気管支喘息 Less

Localization and role of TRPM2 channel in the heart
- Principal Investigator
  
  Shimizu Shunichi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pharmacology in pharmacy
- Research Institution
  Teikyo Heisei University
転写因子FOXP3スプライシングバリアントの機能とアレルギー疾患への関与Principal Investigator
- Principal Investigator
  
  根来孝治
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Collagenous pathology/Allergology
- Research Institution
  Teikyo Heisei University
  Showa University
The pathophysiology in hypoadiponectinemia
- Principal Investigator
  
  NAKANO Yasuko
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Yokohama College of Pharmacy
  Showa University
Attenuation of tumor growth in TRPM2 knockout mice and its mechanism
- Principal Investigator
  
  SHIMIZU Shunichi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Yokohama College of Pharmacy
  Showa University
Mechanisms of impaired function of CD4+CD25+FOXP3+ T cells in patients of asthmaPrincipal Investigator
- Principal Investigator
  
  NEGORO TAKAHARU
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  Showa University
The pathophysiology in hypoadiponectinemia
- Principal Investigator
  
  NAKANO Yasuko
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Showa University
Aggravation mechanism of cardiac ischemia-reperfusion injury through oxidative stress-sensitive channel TRPM2
- Principal Investigator
  
  SHIMIZU Shunichi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Showa University
The effect of low level of adiponectin on inflammation in vivoPrincipal Investigator
- Principal Investigator
  
  NEGORO Takaharu
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  Showa University
Study of adiponectin, structure, functions and clinical meanings.
- Principal Investigator
  
  NAKANO Yasuko
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Showa University
新規活性酸素感受性チャネルTRPM2の喘息への関与及び診断の指標としての可能性
- Principal Investigator
  
  SHIMIZU Shunichi
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Showa University
Molecular biological approach to allergy disease medical treatment
- Principal Investigator
  
  TOBE Takashi
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  Showa University

All 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2006 Other

All Journal Article Presentation Book

[Book] Bronchial asthma-Emerging therapeutic strategies Chapter 4; Immunomechanisms of childhood asthma2012
- Author(s)
  T Negoro, Y Yamamoto, S Shimizu, AH Banham, G Roncador, H Wakabayashi, T Osabe, T Yanai, H Akiyama, K Itabashi and Y Nakano
- Total Pages
  260
- Publisher
  InTech
- Data Source
  KAKENHI-PROJECT-24591471
[Book] Bronchial asthma-Emerging therapeutic strategies, chapter 4 Immune mechanisms of childhood asthma2012
- Author(s)
  T Negoro, Y Yamamoto, S Shimizu, AH Banham, G Roncador, H Wakabayashi, T
- Total Pages
  260
- Publisher
  InTech
- Data Source
  KAKENHI-PROJECT-23590474
[Book] Bronchial asthma-Emerging therapeutic strategies、chapter 4 Immune mechanisms of childhood asthma, ISBN; 978-953-51-0140-62602012
- Author(s)
  Negoro T, Yamamoto Y, Shimizu S, Banham AH, Roncador G, Wakabayashi H, Osabe T, Yanai T, Akiyama H, Itabashi K, Nakano Y, (Editor; Elizabeth Sapey)
- Publisher
  InTech
- Data Source
  KAKENHI-PROJECT-23590474
[Book] 範囲血液・尿化学検査、免疫学的検査 -その数値をどう読むか-【第7版】共同著2010
- Author(s)
  根来孝治、中野泰子
- Publisher
  日本臨床
- Data Source
  KAKENHI-PROJECT-21591288
[Journal Article] Higher Adiponectin expression suppresses neointimal hyperplasia by attenuating the inflammatory response following acceleration of endothelialization in damaged areas in adiponectin transgenic mice2017
- Author(s)
  Omori Y, Suzuki H, Saito K, Shoji M, ISO Y, Negoro T, Koba S, Nakano Y, Kobayashi Y
- Journal Title
  
  Showa Univ. J. Med. Sci.
  
  Volume: 29 Pages: 107-117
- NAID
  130006100252
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09557
[Journal Article] Higher Adiponectin Expression Suppresses Neointimal Hyperplasia by Attenuating the Inflammatory Response Following Acceleration of Endothelialization in Damaged Areas in Adiponectin Transgenic Mice2017
- Author(s)
  Omori Y, Suzuki H, Saito K, Shoji M, Iso Y, Negoro T, Koba S, Nakano Y, Kobayashi Y
- Journal Title
  
  The Showa University Journal of Medical Sciences
  
  Volume: 29 Issue: 2 Pages: 107-117
- DOI
  10.15369/sujms.29.107
- NAID
  130006100252
- ISSN
  0915-6380, 2185-0968
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26460494
[Journal Article] Tyrphostin AG-related compounds attenuate H2O2-induced TRPM2-dependent and -independent cellular responses.2017
- Author(s)
  Shinichiro Yamamoto, Takahiro Toda, Ryo Yonezawa, Takaharu Negoro, Shunichi Shimizu
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: in press Issue: 1 Pages: 68-74
- DOI
  10.1016/j.jphs.2017.05.001
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H01409, KAKENHI-PROJECT-15K09557
[Journal Article] Suppressive Effects of Glucose-Dependent Insulinotropic Polypeptide on Cardiac Hypertrophy and Fibrosis in Angiotensin II-Infused Mouse Models2016
- Author(s)
  Hiromura M., Mori Y., Kohashi K., Terasaki M., Shinmura K., Negoro T., Kawashima H., Kogure M., Wachi T., Watanabe R., Sato K., Kushima H., Tomoyasu M., Nakano Y., Yamada Y., Watanabe T. and Hirano T.
- Journal Title
  
  Circ J
  
  Volume: 80 Issue: 9 Pages: 1988-1997
- DOI
  10.1253/circj.CJ-16-0152
- NAID
  130005406847
- ISSN
  1346-9843, 1347-4820
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09557
[Journal Article] The TAR-RNA binding protein is required for immunoresponses triggered by Cardiovirus infection2016
- Author(s)
  Komuro A., Homma Y., Negoro T., Barber G.N. and Horvath C.M.
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 480 Issue: 2 Pages: 187-193
- DOI
  10.1016/j.bbrc.2016.10.023
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09557
[Journal Article] TRPM2 channels in alveolar epithelial cells mediate bleomycin-induced lung inflammation2016
- Author(s)
  Yonezawa R, Yamamoto S, Takenaka M, Kage Y, Negoro T, Toda T, Ohbayashi M, Numata T, Nakano Y, Yamamoto T, Mori Y, Ishii M, Shimizu S
- Journal Title
  
  Free Radic Biol Med
  
  Volume: 90 Pages: 101-113
- DOI
  10.1016/j.freeradbiomed.2015.11.021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09557, KAKENHI-PROJECT-25462899, KAKENHI-PROJECT-26460494, KAKENHI-PLANNED-26111004, KAKENHI-PROJECT-24249017, KAKENHI-PROJECT-15K08197
[Journal Article] Sensitization of H2O2-induced TRPM2 activation and subsequent interleukin-8 (CXCL8) production by intracellular Fe2+ in human monocytic U937 cells.2015
- Author(s)
  Shimizu S, Yonezawa R, Negoro T, Yamamoto S, Numata T, Ishii M, Mori Y, Toda T.
- Journal Title
  
  The International Journal of Biochemistry & Cell Biology
  
  Volume: 68 Pages: 119-127
- DOI
  10.1016/j.biocel.2015.09.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08197, KAKENHI-PROJECT-15K09557
[Journal Article] Elevated receptor for activated C kinase 1 expression is involved in intracellular Ca2+ influx and potentially associated with compromised regulatory T cell function in patients with asthma2014
- Author(s)
  Negoro T, Shimizu S, Narushima M, Banham AH, Wakabayashi H, Takayanagi R, Hagiwara T, Roncador R, Osabe T, Yanai T, Kin T, Ikeda K, Endo A, Akiyama H, Nakano Y
- Journal Title
  
  Clin Exp Allergy
  
  Volume: 44 Issue: 9 Pages: 1154-1169
- DOI
  10.1111/cea.12375
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24591471, KAKENHI-PROJECT-25462899, KAKENHI-PROJECT-26460494
[Journal Article] Potentiated macrophage activation by acid sensing under low adiponectin levels.2014
- Author(s)
  Negoro T, Kin M, Takuma A, Saito K, Shimizu S, Nakano Y
- Journal Title
  
  Mol Immunol
  
  Volume: 57 Issue: 2 Pages: 141-150
- DOI
  10.1016/j.molimm.2013.08.015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590474, KAKENHI-PROJECT-24591471, KAKENHI-PROJECT-25462899
[Journal Article] A simple smart amplification assay for the rapid detection of human cytomegalovirus in the urine of neonates2014
- Author(s)
  Kohda C, Chiba N, Shimokoba K, Mizuno K, Negoro T, Nakano Y, Tanaka K
- Journal Title
  
  J Virol Methods
  
  Volume: 208 Pages: 160-165
- DOI
  10.1016/j.jviromet.2014.07.034
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24591471, KAKENHI-PROJECT-25462899, KAKENHI-PROJECT-26460494, KAKENHI-PROJECT-26461928
[Journal Article] Inhibitory effects of AG490 on H2O2-induced TRPM2-mediated Ca(2+) entry2014
- Author(s)
  Shimizu S, Yonezawa R, Hagiwara T, Yoshida T, Takahashi N, Hamano S, Negoro T, Toda T, Wakamori M, Mori Y, Ishii M
- Journal Title
  
  Eur J Pharmacol
  
  Volume: 742 Pages: 22-30
- DOI
  10.1016/j.ejphar.2014.08.023
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591471, KAKENHI-PROJECT-25670785
[Journal Article] Metformin modulates GLP-1- and GIP-mediated intracellular signaling under normoglycemic conditions.2013
- Author(s)
  Shinmura K, Negoro T, Shimizu S, Roncador G, Hirano T, Nakano Y.
- Journal Title
  
  Open J Endocri Metab Dis
  
  Volume: 3 Pages: 263-270
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590474
[Journal Article] Metformin modulates GLP-1- and GIP-mediated intracellular signaling under normoglycemic conditions2013
- Author(s)
  Shinmura K, Negoro T, Shimizu S, Roncador G, Hirano T, Nakano Y
- Journal Title
  
  Open J Endocri Metab Dis
  
  Volume: vol.3 Pages: 263-270
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590474
[Journal Article] Metformin modulates GLP-1- and GIP-mediated intracellular signaling under normoglycemic conditions2013
- Author(s)
  K Shinmura, T Negoro, S Shimizu, G Roncador, T Hirano, Y Nakano
- Journal Title
  
  Open J Endocr and Metab Dis
  
  Volume: 3 Issue: 07 Pages: 263-270
- DOI
  10.4236/ojemd.2013.37036
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591471
[Journal Article] Neutrophil TRPM2 channels are implicated in the exacerbation of myocardial ischaemia/reperfusion injury2013
- Author(s)
  Hiroi T, Wajima T, Negoro T, Ishii M, Yasuko Nakano, Kiuchi K, Mori Y, and Shimizu S
- Journal Title
  
  Cardiovasc Res
  
  Volume: vol.97 Issue: 2 Pages: 271-281
- DOI
  10.1093/cvr/cvs332
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590474, KAKENHI-PROJECT-24249017, KAKENHI-PROJECT-24591471, KAKENHI-PUBLICLY-23117709
[Journal Article] Adiponectin enhances calcium-dependency of mouse bladder contraction mediated by protein kinase Cα expression.2013
- Author(s)
  Nobe K, Fujii A, Saito K, Negoro T, Ogawa Y, Nakano Y, Hashimoto T, Honda K.
- Journal Title
  
  J Pharmacol Exp Ther
  
  Volume: 345 Issue: 1 Pages: 62-68
- DOI
  10.1124/jpet.112.202028
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590474, KAKENHI-PROJECT-24591471, KAKENHI-PROJECT-25462899
[Journal Article] Low HCMV DNA Copies Can Establish Infection and Result in Significant Symptoms in Extremely Preterm Infants: A Prospective Study.2012
- Author(s)
  Wakabayashi H, Mizuno K, Kohda C, Negoro T, Maekawa C, Sawato S, Tanaka K, Nakano Y, Murayama J, Taki M, Miyazawa T, Murase M, Aizawa M, Nakano Y, Sakurai M, Takahashi K, Itabashi K.
- Journal Title
  
  Am J Perinatol
  
  Volume: 29 Issue: 05 Pages: 377-382
- DOI
  10.1055/s-0031-1300971
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590474, KAKENHI-PROJECT-23591876, KAKENHI-PROJECT-24591471
[Journal Article] Impaired Ca^<2+> regulation of CD^<4+> CD^<25+> regulatory T cells from pediatric asthma.2011
- Author(s)
  Y. Yamamoto, T. Negoro, A. Hoshi, A. Wakagi, S. Shimizu, A. H. Banham, M. Ishii, H. Akiyama, Y. Kiuchi, S. Sunaga, T. Tobe, G. Roncador, K. Itabashi, and Y. Nakano
- Journal Title
  
  Int Arch Allergy Immunol
  
  Volume: 156 Pages: 148-158
- Data Source
  KAKENHI-PROJECT-21591288
[Journal Article] Impaired Ca2+ regulation of CD4+CD25+ regulatory T cells from pediatric asthma2011
- Author(s)
  Yamamoto Y
- Journal Title
  
  International Archives of Allergy and Immunology
  
  Volume: 156 Issue: 2 Pages: 148-158
- DOI
  10.1159/000322845
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591288, KAKENHI-PROJECT-23590474
[Journal Article] Participation of Th17 and Treg cells in pediatric bronchial asthma2010
- Author(s)
  Y. Yamamoto, T. Negoro, A. Wakagi, A. Hoshi, A. H. Banham, Gi. Roncador, H. Akiyama, T. Tobe, S. Sunaga, Y. Nakano, and K. Itabashi
- Journal Title
  
  J. Health. Sci
  
  Volume: 56 Pages: 589-597
- NAID
  130000425095
- Data Source
  KAKENHI-PROJECT-21591288
[Journal Article] Participation of Th17 and Treg cells in pediatric bronchial asthma2010
- Author(s)
  Yamamoto Y, Negoro T, et al.
- Journal Title
  
  Journal of Health Science
  
  Volume: 56 Pages: 589-597
- NAID
  130000425095
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591288
[Journal Article] A novel enzyme-linked immunosorbent assay specific for high-molecular weight adiponection.2006
- Author(s)
  Nakano Y, Tajima S, Yoshimi A, Akiyama H, Tsushima M, Tanioka T, Negoro T, Tomita M, Tobe T.
- Journal Title
  
  J.Lipid Research (e-pub ahead、印刷中)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590122
[Journal Article] A novel enzyme-linked immunosorbent assay specific for high-molecular weight adiponectin.2006
- Author(s)
  Nakano Y, Tajima S, Yoshimi A, Akiyama H, Tsushima M, Tanioka T, Negoro T, Tomita M, Tobe T.
- Journal Title
  
  J.Lipid Research (e-pub ahead and in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590122
[Presentation] 経口免疫寛容誘導時における減感作状態のEXiLE法を用いた評価2018
- Author(s)
  秋山晴代、西村光平、中村亮介、堀雅之、甲斐茂美、松藤寛、根来孝治、宮澤眞紀、松原康策
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-15K09557
[Presentation] 舌下免疫療法実施時における血清中中和抗体活性のin vitro評価法の開発2017
- Author(s)
  秋山晴代、中村亮介、櫻井大樹、平野吉彬、根来孝治、岡本美孝
- Organizer
  第66回日本アレルギー学会学術大会
- Data Source
  KAKENHI-PROJECT-15K09557
[Presentation] 喘息患者における各FOXP3バリアント発現とその機能との関係2017
- Author(s)
  山本佳樹、根来孝治、成島道昭、秋山　晴代、清水　俊一、山本　伸一郎、戸田　雄大、高柳隆章、板橋稼頭央
- Organizer
  第66回日本アレルギー学会学術大会
- Data Source
  KAKENHI-PROJECT-15K09557
[Presentation] 易炎症性マウスを用いた未病に関与するターゲット因子の探索2016
- Author(s)
  秋山晴代、長部隆広、根来孝治、荒木真由美、瀬戸山央、青木信義、渡邊裕子、甲斐茂美、中野泰子、宮澤眞紀
- Organizer
  日本薬学会
- Place of Presentation
  横浜
- Year and Date
  2016-03-26
- Data Source
  KAKENHI-PROJECT-26460494
[Presentation] アディポネクチンアンチセンス、センストランスジェニックマウスの表現型解析2016
- Author(s)
  中野泰子、秋山晴代、目加田和之、若菜茂晴、齊藤清美、巖本三壽、吉木淳、根来孝治
- Organizer
  第８９回日本生化学会大会
- Place of Presentation
  仙台
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-26460494
[Presentation] 喘息患者における各FOXP3バリアント発現とその機能との関係2016
- Author(s)
  山本佳樹、根来孝治、成島道昭、秋山　晴代、清水　俊一、山本　伸一郎、戸田　雄大、高柳隆章、板橋稼頭央
- Organizer
  第65回日本アレルギー学会学術大会
- Place of Presentation
  東京国際フォーラム（東京都）
- Year and Date
  2016-06-17
- Data Source
  KAKENHI-PROJECT-15K09557
[Presentation] Involvement of RNAi accessory factors in MDA5/LGP2-mediated cellular responses by Cardiovirus infection2016
- Author(s)
  Komuro Akihikko, Negoro Takaharu, Barber Glen, Horvath Curt
- Organizer
  第45回日本免疫学会学術総会
- Place of Presentation
  沖縄コンベンションセンター（沖縄）
- Year and Date
  2016-12-05
- Data Source
  KAKENHI-PROJECT-15K09557
[Presentation] アディポネクチンアンチセンス、センストランスジェニックマウスの表現型解析2016
- Author(s)
  中野泰子、秋山晴代、目加田和之、若菜茂晴、齊藤清美、巖本三壽、吉木淳、根来孝治
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  仙台国際センター（仙台）
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-15K09557
[Presentation] CD4+CD25high T細胞の小児期における表面抗原解析と喘息患者における参加ストレス応答の検討2016
- Author(s)
  山本　佳樹、成島　道昭、根来　孝治、高柳　隆章、板橋　稼頭央
- Organizer
  第65回日本アレルギー学会学術大会
- Place of Presentation
  東京国際フォーラム
- Year and Date
  2016-06-17
- Data Source
  KAKENHI-PROJECT-15K09557
[Presentation] メトホルミンによる膵β細胞のインクレチン刺激細胞内シグナル制御機構の検討2013
- Author(s)
  新村京子,根来孝治,中野泰子,平野勉
- Organizer
  第56回日本糖尿病学会年次学術集会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-23590474
[Presentation] Modulation of incretin actions in pancreatic β-cells by metformin.2013
- Author(s)
  Kyoko Shinmura, Takaharu Negoro, Yasuko Nakano, Tsutomu Hirano
- Organizer
  49th Annual meeting of the European association for the study of diabetes
- Place of Presentation
  Barcelona, Spain
- Data Source
  KAKENHI-PROJECT-23590474
[Presentation] アディポネクチンによる抗炎症作用の解析2013
- Author(s)
  谷岡利裕，躰長義直，山田倫世，根来孝治，中野泰子
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23590474
[Presentation] メトホルミンによる膵β細胞のインクレチン刺激細胞内シグナル制御機構の検討2013
- Author(s)
  新村京子，根来孝治，中野泰子，平野勉
- Organizer
  第56回　日本糖尿病学会年次学術集会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-23590474
[Presentation] Modulation of incretin actions in pancreaticβ-cells by metformin2013
- Author(s)
  Shinmura K, Negoro T, Nakano Y, Hirano T
- Organizer
  49th Annual meeting of the European association for the study of diabetes
- Place of Presentation
  スペイン
- Data Source
  KAKENHI-PROJECT-23590474
[Presentation] アディポネクチンによる抗炎症作用の解析2013
- Author(s)
  谷岡利裕,躰長義直,山田倫世,根来孝治,中野泰子
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23590474
[Presentation] Potentiated macrophage activation by acid sensing under low adiponectin levels2012
- Author(s)
  Negoro T, Akiyama H, Tanioka T, Saito K, Shimizu S, and Nakano Y
- Organizer
  The 64th Fujihara Seminar International Symposium on Adiponectin Biology and Medicine
- Place of Presentation
  苫小牧
- Data Source
  KAKENHI-PROJECT-23590474
[Presentation] Potentiated macrophage activation by acid sensing under low adiponectin levels2012
- Author(s)
  T Negoro, H Akiyama, T Tanioka, K Saito, S Shimiz
- Organizer
  The 64th Fujihara Seminar
- Place of Presentation
  北海道苫小牧市
- Data Source
  KAKENHI-PROJECT-24591471
[Presentation] 関節リウマチにおけるアディポネクチンの生理的機能解明2012
- Author(s)
  秋山晴代,嶋田紘也,齊藤清美,根来孝治,中野泰子
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23590474
[Presentation] 関節リウマチにおけるアディポネクチンの生理的機能解明2012
- Author(s)
  秋山晴代，嶋田紘也，齊藤清美，根来孝治，中野泰子
- Organizer
  第35回　日本分子生物学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23590474
[Presentation] アディポネクチンにより誘導されるIRF-7が破骨細胞分化を制御する2012
- Author(s)
  谷岡　利裕、石直　南、杉原　希美、平川　琴美、石原　伸恵、根来　孝治、中野　泰子
- Organizer
  第85回　日本生化学会大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23590474
[Presentation] アディポネクチンにより誘導されるIRF-7が破骨細胞分化を制御する2012
- Author(s)
  谷岡利裕、石直南、杉原希美、平川琴美、石原伸恵、根来孝治、中野泰子
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23590474
[Presentation] Effect of Lower adiponectin concentration exert a harmful influence2012
- Author(s)
  Saito K, Negoro T, Sato H, Nakano Y
- Organizer
  The 64th Fujihara Seminar International Symposium on Adiponectin Biology and Medicine
- Place of Presentation
  苫小牧
- Data Source
  KAKENHI-PROJECT-23590474
[Presentation] 関節リウマチにおけるアディポネクチンの生理的機能解明2012
- Author(s)
  秋山晴代，嶋田紘也，齊藤清美，根来孝治，中野泰子
- Organizer
  第35回　日本分子生物学会年会
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-24591471
[Presentation] Effect of RACK1 on impaired functions of CD4+CD25+ regulatory T cells from asthma subjects2011
- Author(s)
  Negoro T, Shimizu S, Narushima M, Endo A, Tanioka T, Nakano Y
- Organizer
  第40回日本免疫学会学術集会
- Place of Presentation
  幕張
- Data Source
  KAKENHI-PROJECT-23590474
[Presentation] Effect of RACK1 on impaired functions of CD4+CD25+ regulatory T cells from asthma subjects2011
- Author(s)
  根来孝治
- Organizer
  第40回日本免疫学会学術集会
- Place of Presentation
  幕張
- Year and Date
  2011-11-28
- Data Source
  KAKENHI-PROJECT-21591288
[Presentation] アディポネクチンによる破骨細胞分化抑制機構の解明2011
- Author(s)
  石直南、谷岡利裕、平川琴美、根来孝治、中野泰子
- Organizer
  第55回日本薬学会関東支部大会
- Place of Presentation
  千葉
- Year and Date
  2011-10-08
- Data Source
  KAKENHI-PROJECT-23590474
[Presentation] iNOS Promotes Proteasome-Dependent Degradation of IRS-2 by Activating GSK-3βin Pancreaticβ-cells2011
- Author(s)
  Tanioka T, Tamura Y, Mao J, Kitamura T, Negoro T, Nakano Y, Kaneki M
- Organizer
  第84回日本生化学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23590474
[Presentation] マウス心臓の虚血-再灌流の進展におけるTRPM2チャネルの関与2010
- Author(s)
  廣井理人、輪島輝明、香西大輔、根来孝治、木内祐二、森泰生、清水俊一
- Organizer
  第83回日本薬理学会年会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-21590104
[Presentation] マウス心臓の虚血-再灌流障害の進展におけるTRPM2チャネルの関与2010
- Author(s)
  清水俊一, 根来孝治
- Organizer
  第83回日本薬理学会年会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2010-03-16
- Data Source
  KAKENHI-PROJECT-21590104
[Presentation] Effect of adiponectin on macrophage viae pH-sensor2010
- Author(s)
  Negoro Takaharu
- Organizer
  14^<th> International Congress of Immunology
- Place of Presentation
  Kobe
- Year and Date
  2010-08-25
- Data Source
  KAKENHI-PROJECT-21591288
[Presentation] Effect of adiponectin on macrophage via the pH sensor2010
- Author(s)
  Takaharu Negoro, 他
- Organizer
  14th ICI 2010 annual meeting
- Place of Presentation
  Kobe, Japan
- Data Source
  KAKENHI-PROJECT-21591288
[Presentation] 炎症性疾患の発症と進展におけるTRPM2の役割2009
- Author(s)
  廣井理人、山本伸一郎、輪島輝明、根来孝治、木内祐二、森泰生、清水俊一
- Organizer
  第5回TRPチャネル研究会
- Place of Presentation
  岡崎
- Year and Date
  2009-06-05
- Data Source
  KAKENHI-PROJECT-21590104
[Presentation] 非定型抗精神病薬の糖尿病病態発症機構の解明
- Author(s)
  秋山晴代、細野由佳、鈴木　彩、須佐友美、柴田理映、杉原希美、根来孝治、中野泰子
- Organizer
  第84回　日本生化学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23590474
[Presentation] Adiponectin preferentially inhibit LPS-induced IL-1βexpression on macrophage.
- Author(s)
  Tanioka T, Tainaga Y, Yamada Y, Negoro T, Nakano Y.
- Organizer
  The 22nd International Symposium on Molecular Cell Biology of Macrophages
- Place of Presentation
  神戸
- Year and Date
  2014-06-01 – 2014-06-03
- Data Source
  KAKENHI-PROJECT-26460494
[Presentation] 喘息患者における制御性Ｔ細胞の機能低下へのRACK1分子の関与
- Author(s)
  Negoro Takaharu, Shimizu Shunichi, Narushima Michiaki, Endo Atsushi, Tanioka Toshihiro, Nakano Yasuko
- Organizer
  第40回　日本免疫学会学術集会
- Place of Presentation
  幕張
- Data Source
  KAKENHI-PROJECT-23590474
[Presentation] アディポネクチンによる破骨細胞分化抑制機構の解明
- Author(s)
  石直　南、谷岡　利裕、平川　琴美、根来　孝治、中野　泰子
- Organizer
  第55回日本薬学会関東支部大会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-23590474
[Presentation] 極低出生体重児における経母乳サイトメガロウィルス（CMV）感染予防に対する研究第1報
- Author(s)
  水野克己、高橋兼一郎、中野有也、宮沢篤生、村瀬正彦、桜井基一郎、相沢まどか、板橋家頭夫、幸田　力、田中和生、中野泰子、根来孝治、前川千亜紀、若林仁美
- Organizer
  第47回　日本周産期・新生児医学会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23590474
[Presentation] アディポネクチンによる炎症性サイトカイン抑制作用の解析
- Author(s)
  谷岡利裕、躰長義直、山田倫世、根来孝治、中野泰子
- Organizer
  第35回日本炎症・再生医学会
- Place of Presentation
  沖縄
- Year and Date
  2014-07-01 – 2014-07-04
- Data Source
  KAKENHI-PROJECT-26460494
[Presentation] iNOS Promotes Proteasome-Dependent Degradation of IRS-2 by Activating GSK-3β in Pancreatic β-cells.
- Author(s)
  T. Tanioka, Y. Tamura, J. Mao, T. Kitamura, T. Negoro, Y. Nakano, M. Kaneki.
- Organizer
  第84回日本生化学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23590474
[Presentation] Detection of Human cytomegalovirus DNA in the urine from infants by Real-Time PCR
- Author(s)
  Chikara Kohda, Kazuo Tanaka, Katsumi Mizuno, Yasuko Nakano,　Takaharu Negoro, Chiaki Maekawa
- Organizer
  IUMS 2011
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23590474

1. NAKANO Yasuko (20155790)

# of Collaborated Projects: 7 results

# of Collaborated Products: 45 results
2. SHIMIZU Shunichi (60196516)

# of Collaborated Projects: 5 results

# of Collaborated Products: 7 results
3. TANIOKA Toshihiro (80360585)

# of Collaborated Projects: 5 results

# of Collaborated Products: 15 results
4. TOBE Takashi (90102368)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
5. ISHII Masakazu (30307061)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. SAITO Kiyomi (70307065)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. NARUSHIMA Michiaki (30255856)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. KOBA Shinji (20276546)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. YATSUDUKA Masashi (20119275)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. NUMATA Tomohiro (20455223)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. 鈴木一 (80053891)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 木内祐二 (50204821)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 向後麻里 (70343499)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 戸田雄大 (30573852)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

NEGORO Takaharu 根来 孝治

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転写因子FOXP3スプライシングバリアントの機能とアレルギー疾患への関与Principal Investigator

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Mechanisms of impaired function of CD4+CD25+FOXP3+ T cells in patients of asthmaPrincipal Investigator

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The effect of low level of adiponectin on inflammation in vivoPrincipal Investigator

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[Book] Bronchial asthma-Emerging therapeutic strategies Chapter 4; Immunomechanisms of childhood asthma2012

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[Book] Bronchial asthma-Emerging therapeutic strategies, chapter 4 Immune mechanisms of childhood asthma2012

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[Book] Bronchial asthma-Emerging therapeutic strategies、chapter 4 Immune mechanisms of childhood asthma, ISBN; 978-953-51-0140-62602012

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[Book] 範囲 血液・尿化学検査、免疫学的検査 -その数値をどう読むか-【第7版】 共同著2010

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NEGORO Takaharu 根来孝治

[Book] 範囲血液・尿化学検査、免疫学的検査 -その数値をどう読むか-【第7版】共同著2010