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KOBAYASHI Michihiko  小林 達彦

ORCIDConnect your ORCID iD *help
… Alternative Names

小林 逹彦  コバヤシ ミチヒコ

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Researcher Number 70221976
Other IDs
External Links
Affiliation (Current) 2025: 筑波大学, 生命環境系, 教授
Affiliation (based on the past Project Information) *help 2011 – 2024: 筑波大学, 生命環境系, 教授
2010: University of Tsukuba, 生命環境科学研究科, 教授
2007 – 2010: University of Tsukuba, 大学院・生命環境科学研究科, 教授
2009: 筑波大学, 大学院生命環境科学研究科, 教授
2006: University of Tsukuba, Graduate School of Life and Environmental Sciences, Professor, 大学院生命環境科学研究科, 教授 … More
2004 – 2005: University of Tsukuba, Graduate School of Life and Envirolmental Sciences, Professor, 大学院・生命環境科学研究科, 教授
1999 – 2003: Tsukuba Univ. Div. of Appl. Biochem., Professor, 応用生物化学系, 教授
1998: 京大, (連合)農学研究科, 講師
1997 – 1998: KYOTO UNIVERSITY,Graduate School of Agriculture, Lecturer, 農学研究科, 講師
1996: 京都大学。農学部, 講師
1993 – 1996: Fac.Agric.Kyoto Univ.Lec., 農学部, 講師
1991 – 1992: Kyoto University, Dept. Agric. Chem. Assistant Professor, 農学部, 助手 Less
Review Section/Research Field
Principal Investigator
Applied microbiology / 応用微生物学・応用生物化学 / Applied molecular and cellular biology / Medium-sized Section 38:Agricultural chemistry and related fields / Science and Engineering / Applied biochemistry / Environmental technology/Environmental materials / Applied molecular and cellular biology
Except Principal Investigator
応用微生物学・応用生物化学 / 応用微生物学・発酵学 … More / Applied molecular and cellular biology / Environmental engineering and reduction of environmental burden / Complex systems / Basic Section 38060:Applied molecular and cellular biology-related / Boundary agriculture / Biophysics / Applied biochemistry / Environmental technology/Environmental materials / Biofunction/Bioprocess Less
Keywords
Principal Investigator
微生物 / 酵素 / 遺伝子 / ニトリルヒドラターゼ / 代謝 / Rhodococcus / ニトリル / コバルト / 発現 / アミド … More / Gene / アミダーゼ / Nitrilase / ニトリラーゼ / Amide / Nitrile hydratase / プロモーター / イソニトリル / 精製 / トランスポーター / 塩基配列 / Amidase / イソニトリルヒドラターゼ / Expression / Promoter / 誘導 / N-置換ホルムアミド / 重金属 / ロドコッカス / N-substituted formamide / Nitrile / N-substituted formamide deformylase / Isonitrile hydtratase / Aldoxime dehydratase / アシド / イソニトリルヒドラーゼ / ニトリルイソニトリル / N-置換ホルムアシド分解酵素 / アルドキシムデヒドラターゼ / アシルCoA合成酵素 / N-置換ホルムアミド分解酵素 / Isonitvile hydratase / Isonitvile / Nitvile / 加水分解酵素 / アシダーゼ / Auxin / Indoleacetic acid / Plant hormone / オーキシン / インドール酢酸 / 植物ホルモン / Induction / promoter / イソバレロニトリル / Sequence / 転写開始点 / クロトンアミド / トランスポザ-ゼ / アミダ-セ / 細菌 / 分解 / バイオテクノロジー / ホロタンパク質 / アポタンパク質 / 成熟化 / タンパク質 / 大量発現 / CCA付加酵素 / ポリA付加酵素 / RNA末端形成システム / アーキア / D-システイン / D-アミノ酸 / 膜タンパク / 輸送タンパク / トランスポータ / 輸送タンパク質 / ニッケル / 立体特異性 / Rhodococcus rhodochrous … More
Except Principal Investigator
微生物 / 酵素 / Mortierella alpina / Fusarium oxysporum / 高度不飽和脂肪酸 / アラキドン酸 / ラクトナーゼ / パントラクトン / polyunsaturated fatty acid / 代謝 / SPring-8 / Brevibacterium / ニトリルヒドラターゼ / Desaturase / 不飽和化酵素 / Lactonase / Pantolactone / arachidonic acid / ジホモ-γ-リノレン酸 / Sporobolomyces salmonicolor / ニトリラーゼ / 応用微生物学 / 廃棄物処理 / 精製 / 圃場 / オミクス / 微生物機能 / Biofilm / Treatment technology / Alkali-tolerant bacteria / Degrading-bacteria / micrcystin / Water bloom / Eutrophic lake / Aquatic environment / nodularin / ラン藻由来有毒物 / 生物膜 / アルカリ耐性菌 / microcystin / ラン藻由来有毒物質 / バイオフィルム / 処理技術 / 耐アルカリ性菌 / 分解菌 / micocystin / アオコ / 富栄養化湖沼 / 水環境 / Site-directed mutant protein / Large-angle Oscillation Technique / Four-dimensional Crystallography / Photo-activation / Nitrile Hydratase / イソニトリルヒドラターゼ / 小型カッパーゴニオメータ / SPning-8 / 部位特異的変異体 / 大角度回転結晶法 / 4次元結晶構造解析 / 光活性化過程 / Cytochrome b5 / γ-Linolenic acid / Arachidsnic acid / Poly unsaturated fatty acid / desaturase-mutant / desaturase / γ-linolenic acid / シトクロームb5 / シトクロームb_5 / γ-リノレン酸 / Lacfonase / stereo specificity / Lactone-ring-cleaving enzyme / 立体選択的 / Brevibacterium protophormiae / 開裂酵素 / ラクトン / 結晶構造解析 / Fusarium / 立体選択性 / ラクトン環開裂酵素 / beta-oyanoalanine / nitrilase / beta-cyanoalanine synthase / nitrile hydratase / C1 compound / Cyanide / PLP / Pseudomonas ovalis / Cl化合物 / β-シアノアラニン / β-シアノアラニン合成酵素 / C1化合物 / シアン / Immobilized enzyme / Enzymatic resolution / 固定化酵素 / 酵素的光学分割 / Docosahexaenoic acid / Furan fatty acid / Ca channel blocker / Curcumin / Propyl gallate / Inhibitor / 不飽和脂肪酸 / 不飽和化酸素 / ドコサヘキサエン酸 / フラン環含有脂肪酸 / カルシウム拮抗薬 / クルクミン / プロピルガ-レート / 阻害剤 / Single cell oil / Functional lipid / Polyunsaturated fatty acid / Mead acid / Arachidonic acid / Moritierella alpina / Single Cell Oil / 機能性油脂 / シングルセルオイル / シンブルセルオイル / 機能性脂質 / ミ-ド酸 / High-mannose sugarchain / Optical resolution / ハイマンノース型糖鎖 / 光学分割 / dihomo- -linolenic acid / ジホモ-γ-リルン酸 / 4-halo-3-hydroxybutanoaic / Aldehyde reductase / L-carnitine / アルデヒド還元酵素 / R-(-)-4-ハロ-3-ヒドロキシブタン酸エステル / 酵素的不斉合成 / 4-ハロ-3-ヒドロキシブタン酸エステル / Sporoboromyces salmonicolor / アルデヒドレダクターゼ / 4-ハロ-3ヒドロキシブタン酸エステル / Spovoboromyces salmonicdor / L-カルニチン / aromatic acylarylamidase / optically active amines / optically acitive amino acids / N-carbamoylamino acid amidohydrolase / nucleoside oxidase / dihydropyrimidinase / hydantoinase / 光学活性アミン / 光学活性アミノ酸 / ヒダントイン / Nーカルバモイルアミノ酸 / ジヒドロピリミジナ-ゼ / ヒダントイナ-ゼ / ニトリル / アミン / N-署換ホルムアミド / イソニトリル / 分解 / 油滴小胞 / 脂肪酸分泌 / 分泌機構 / Rhodococcus rhodochrous / キメラ酵素 / インドールアセトニトリル / Alcaligenes faecalis / インドール酢酸 Less
  • Research Projects

    (49 results)
  • Research Products

    (103 results)
  • Co-Researchers

    (31 People)
  •  Elucidation of diverse curcumin metabolism by microorganismsPrincipal Investigator

    • Principal Investigator
      小林 達彦
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 38:Agricultural chemistry and related fields
    • Research Institution
      University of Tsukuba
  •  Elucidation and application of diverse catechin metabolism by microorganismsPrincipal Investigator

    • Principal Investigator
      小林 達彦
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Challenging Research (Pioneering)
    • Review Section
      Medium-sized Section 38:Agricultural chemistry and related fields
    • Research Institution
      University of Tsukuba
  •  Functional analysis of novel microbial curcumin metabolism

    • Principal Investigator
      HASHIMOTO Yoshiteru
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 38060:Applied molecular and cellular biology-related
    • Research Institution
      University of Tsukuba
  •  Functional analysis of the flavonoid-converting machineryPrincipal Investigator

    • Principal Investigator
      小林 達彦
    • Project Period (FY)
      2019 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Science and Engineering
    • Research Institution
      University of Tsukuba
  •  Modeling the post-Koch ecosystem

    • Principal Investigator
      高谷 直樹
    • Project Period (FY)
      2019 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Complex systems
    • Research Institution
      University of Tsukuba
  •  Functional analyses of enzymes and the accessory proteins involved in industrial production of amide compounds

    • Principal Investigator
      HASHIMOTO Yoshiteru
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Applied molecular and cellular biology
    • Research Institution
      University of Tsukuba
  •  Turmeric degradation by microorganisms from soil

    • Principal Investigator
      HASHIMOTO Yoshiteru
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Biofunction/Bioprocess
    • Research Institution
      University of Tsukuba
  •  Studies on unique inducible protein expression system for streptomycetesPrincipal Investigator

    • Principal Investigator
      KOBAYASHI Michihiko
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Applied microbiology
    • Research Institution
      University of Tsukuba
  •  Microbial degradation of bioactive substance from turmericPrincipal Investigator

    • Principal Investigator
      KOBAYASHI Michihiko
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Applied microbiology
    • Research Institution
      University of Tsukuba
  •  Studies on microbial degradation of a nitrogen-containing environmentally hazardous compound

    • Principal Investigator
      HASHIMOTO Yoshiteru
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Environmental engineering and reduction of environmental burden
    • Research Institution
      University of Tsukuba
  •  Characterization of an N3 compound-degrading enzymePrincipal Investigator

    • Principal Investigator
      KOBAYASHI Michihiko
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Applied microbiology
    • Research Institution
      University of Tsukuba
  •  Comprehensive elucidation and application of the function of enzymes involved in cleavage and synthesis of a carbon-nitrogen bondPrincipal Investigator

    • Principal Investigator
      KOBAYASHI Michihiko
    • Project Period (FY)
      2011 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Applied biochemistry
    • Research Institution
      University of Tsukuba
  •  ニトリル代謝関連酵素群の分子機能解析と有用物質生産への利用Principal Investigator

    • Principal Investigator
      小林 達彦
    • Project Period (FY)
      2011
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Applied microbiology
    • Research Institution
      University of Tsukuba
  •  イソニトリル代謝酵素群の分子機能解析

    • Principal Investigator
      橋本 義輝
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Applied molecular and cellular biology
    • Research Institution
      University of Tsukuba
  •  N3化合物分解代謝に関わる酵素の機能解析Principal Investigator

    • Principal Investigator
      小林 達彦
    • Project Period (FY)
      2010
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Environmental technology/Environmental materials
    • Research Institution
      University of Tsukuba
  •  新規酵素翻訳後修飾機構の解析

    • Principal Investigator
      橋本 義輝
    • Project Period (FY)
      2010 – 2011
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Applied biochemistry
    • Research Institution
      University of Tsukuba
  •  微生物酵素の新規活性化機構の解析Principal Investigator

    • Principal Investigator
      小林 達彦
    • Project Period (FY)
      2009
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Applied microbiology
    • Research Institution
      University of Tsukuba
  •  Analyses of the N-substituted formamide metabolic pathway and their applications to the production of useful compoundsPrincipal Investigator

    • Principal Investigator
      KOBAYASHI Michihiko
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Applied microbiology
    • Research Institution
      University of Tsukuba
  •  微生物によるN3化合物分解代謝

    • Principal Investigator
      橋本 義輝
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Environmental technology/Environmental materials
    • Research Institution
      University of Tsukuba
  •  新規タンパク質成熟化機構の解明Principal Investigator

    • Principal Investigator
      小林 達彦
    • Project Period (FY)
      2007
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Applied molecular and cellular biology
    • Research Institution
      University of Tsukuba
  •  アーキアにおけるRNA末端形成システムの解明Principal Investigator

    • Principal Investigator
      小林 達彦
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Applied microbiology
    • Research Institution
      University of Tsukuba
  •  Establishment of Treatment Technique of Cyanobacterial Toxin using Function by Microbial Community

    • Principal Investigator
      SUGIURA Norio
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Boundary agriculture
    • Research Institution
      University of Tsukuba
  •  大腸菌がD体のアミノ酸を単一炭素源として利用する!Principal Investigator

    • Principal Investigator
      小林 達彦
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      応用微生物学・応用生物化学
    • Research Institution
      University of Tsukuba
  •  Functional analysis of non-proteolytic enzymes involved in carbon-nitrogen bond cleavagePrincipal Investigator

    • Principal Investigator
      KOBAYASHI Michihiko
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      応用微生物学・応用生物化学
    • Research Institution
      University of Tsukuba
  •  Four-Dimensional Protein Crystallography of Nitrile Hydratase Reaction

    • Principal Investigator
      KAMIYA Nobuo
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biophysics
    • Research Institution
      RIKEN
  •  Development of Rhodococcus promoter for utilization in actinomycetesPrincipal Investigator

    • Principal Investigator
      KOBAYASHI Michihiko
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      応用微生物学・応用生物化学
    • Research Institution
      University of Tsukuba
  •  重金属コバルトをターゲティングするタンパク質の分子認識機構の解明と応用Principal Investigator

    • Principal Investigator
      小林 達彦
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      University of Tsukuba
  •  脂質分泌生産機構の解明と応用

    • Principal Investigator
      清水 昌
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      応用微生物学・応用生物化学
    • Research Institution
      Kyoto University
  •  コバルト輸送タンパク質の構造と機能解析Principal Investigator

    • Principal Investigator
      小林 達彦
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Applied molecular and cellular biology
    • Research Institution
      University of Tsukuba
  •  Analysis of reaction mechanisums and molecular evolution of C-N hydrolasesPrincipal Investigator

    • Principal Investigator
      KOBAYASHI Mikihiko
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      応用微生物学・応用生物化学
    • Research Institution
      University of Tsukuba
  •  コバルト輸送タンパク質の構造と機能解析Principal Investigator

    • Principal Investigator
      小林 達彦
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      応用微生物学・応用生物化学
    • Research Institution
      Kyoto University
  •  Molecular breeding of filamenfous fungi for usefile lipid production

    • Principal Investigator
      SHIMIZ Sakayu
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      応用微生物学・応用生物化学
    • Research Institution
      KYOTO UNIVERSITY
  •  インドール酢酸生合成酵素の分子機能解析

    • Principal Investigator
      清水 昌
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      応用微生物学・応用生物化学
    • Research Institution
      Kyoto University
  •  Development of production process of useful compounds from cyanide.Principal Investigator

    • Principal Investigator
      OGAWA Jun, 小林 達彦
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      応用微生物学・応用生物化学
    • Research Institution
      KYOTO UNIVERSITY
  •  Analysis of stereospecificity control mechanism in microbial lactonohydrolase.

    • Principal Investigator
      KATAOKA Michihiko
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      応用微生物学・応用生物化学
    • Research Institution
      KYOTO UNIVERSITY
  •  重金属含有酵素・ニトリルヒドラターゼの構造機能解析Principal Investigator

    • Principal Investigator
      小林 達彦
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto University
  •  コバルトトランスポータの構造と機能Principal Investigator

    • Principal Investigator
      小林 逹彦
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto University
  •  Screening, functional analysis and application of polyunsaturated fatty acid-desaturase inhibitors

    • Principal Investigator
      SHIMIZU Sakayu
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      応用微生物学・応用生物化学
    • Research Institution
      KYOTO UNIVERSITY
  •  Studies on enzymes and genes involved in biosynthesis of plant hormone, auxinPrincipal Investigator

    • Principal Investigator
      KOBAYASHI Michihiko
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Applied molecular and cellular biology
    • Research Institution
      KYOTO UNIVERSITY
  •  Development of enzymatic resolution process of pantolactone by fungal lactonase

    • Principal Investigator
      SHIMIZU Sakayu
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      応用微生物学・応用生物化学
    • Research Institution
      KYOTO UNIVERSITY
  •  重金属トランスポーターの構造と機能Principal Investigator

    • Principal Investigator
      小林 達彦
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto University
  •  Development of novel expression vectors utilizing gene promoters involved in nitrile metabolismPrincipal Investigator

    • Principal Investigator
      KOBAYASHI Michihiko
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Applied molecular and cellular biology
    • Research Institution
      KYOTO UNIVERSITY
  •  Structure and function of a novel fungal enzyme, lactonohydrolase, and its application to optical resolution of pantolactone

    • Principal Investigator
      SHIMIZU Sakayu
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      応用微生物学・応用生物化学
    • Research Institution
      KYOTO UNIVERSITY
  •  Production of functional single cell oils

    • Principal Investigator
      SHIMIZU Sakaya
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      応用微生物学・応用生物化学
    • Research Institution
      KYOTO UNIVERSITY
  •  Molecular functional analysis of gene cluster involved in nitrile metabolismPrincipal Investigator

    • Principal Investigator
      KOBAYASHI Michihiko
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      応用微生物学・応用生物化学
    • Research Institution
      KYOTO UNIVERSITY
  •  アミド分解および合成酵素の構造解析とその応用Principal Investigator

    • Principal Investigator
      小林 達彦
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      応用微生物学・応用生物化学
    • Research Institution
      Kyoto University
  •  Production of polyunsaturated fatty acids by microorganisms

    • Principal Investigator
      SHIMIZU Sakayu
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      応用微生物学・発酵学
    • Research Institution
      KYOTO UNIVERSITY
  •  Enzymatic synthesis of L-carnitine and related alcohols

    • Principal Investigator
      SHIMIZU Sakayu, 山田 秀明
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      応用微生物学・発酵学
    • Research Institution
      KYOTO UNIVERSITY
  •  Production of optically active amino acids and their derivatives by microbial hydantoinase

    • Principal Investigator
      SHIMIZU Sakayu
    • Project Period (FY)
      1990 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      応用微生物学・発酵学
    • Research Institution
      Kyoto University

All 2021 2020 2019 2017 2016 2015 2014 2013 2011 2010 2009 2008 2007 2005 2004 2003 2002 Other

All Journal Article Presentation Book

  • [Book] 構造生物学-ポストゲノム時代のタンパク質研究-"自然界から有用酵素を収集する方法:イソニトリル代謝関連酵素群"2007

    • Author(s)
      橋本義輝、小林達彦
    • Publisher
      共立出版
    • Data Source
      KAKENHI-PROJECT-19208008
  • [Journal Article] Metal chaperone, NhpC, involved in the metallocenter biosynthesis of nitrile hydratase2021

    • Author(s)
      Hashimoto Yoshiteru、Ube Yuko、Doi Shiori、Kumano Takuto、Kobayashi Michihiko
    • Journal Title

      J. Gen. Appl. Microbiol.

      Volume: 67 Issue: 1 Pages: 24-32

    • DOI

      10.2323/jgam.2020.03.003

    • NAID

      130008025417

    • ISSN
      0022-1260, 1349-8037
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H03962
  • [Journal Article] Amide compound synthesis by adenylation domain of bacillibactin synthetase2017

    • Author(s)
      Abe, T., Hashimoto, Y., Sugimoto, S., Kobayashi, K., Kumano, T., & Kobayashi, M.
    • Journal Title

      J. Antibiot.,

      Volume: 70 Issue: 4 Pages: 435-442

    • DOI

      10.1038/ja.2016.117

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-23228002
  • [Journal Article] New function of aldoxime dehydratase: Redox catalysis and the formation of an expected product2017

    • Author(s)
      Yamada, M., Hashimoto, Y., Kumano, T., Tsujimura, S. & Kobayashi, M.
    • Journal Title

      PLOS ONE

      Volume: 12 Issue: 4 Pages: e0175846-e0175846

    • DOI

      10.1371/journal.pone.0175846

    • NAID

      120007129139

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-23228002
  • [Journal Article] Peptide Bond Synthesis by a Mechanism Involving an Enzymatic Reaction and a Subsequent Chemical Reaction2016

    • Author(s)
      Abe, T., Hashimoto, Y., Zhuang, Y., Ge, Y., Kumano, T., & Kobayashi, M.
    • Journal Title

      J. Biol. Chem.,

      Volume: 291 Issue: 4 Pages: 1735-1750

    • DOI

      10.1074/jbc.m115.700989

    • NAID

      120007128491

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-23228002
  • [Journal Article] Crystal structure of aldoxime dehydratase and its catalytic mechanism involved in carbon-nitrogen triple-bond synthesis2013

    • Author(s)
      Nomura, J., Hashimoto, H., Ohta, T., Hashimoto, Y., Wada, K., Naruta, Y., Oinuma, K-I., & Kobayashi, M.
    • Journal Title

      Proc. Natl. Acad. Sci. USA

      Volume: 110 Issue: 8 Pages: 2810-2815

    • DOI

      10.1073/pnas.1200338110

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23228002, KAKENHI-PROJECT-24550080, KAKENHI-PROJECT-24657076, KAKENHI-PUBLICLY-23121524
  • [Journal Article] Unique biogenesis of high-molecular mass multimeric metalloenzyme nitrile hydratase : Intermediates and a proposed mechanism for self-subunit swapping maturation2010

    • Author(s)
      Zhou, Z., Hashimoto, Y., Cui, T., Washizawa, Y., Mino, H., Kobayashi, M.
    • Journal Title

      Biochemistry

      Volume: 49 Pages: 9638-9648

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22658033
  • [Journal Article] ニトリルヒドラターゼの新しい成熟化機構の発見2010

    • Author(s)
      橋本義輝、小林達彦
    • Journal Title

      バイオサイエンスとインダスハグー

      Volume: 68 Pages: 113-116

    • NAID

      10026195063

    • Data Source
      KAKENHI-PROJECT-22658033
  • [Journal Article] Novel isonitrile hydratase involved in isonitrile metabolism2010

    • Author(s)
      Sato, H., Hashimoto, Y., Fukatsu, H., Kobayashi, M.
    • Journal Title

      J.Biol.Chem.

      Volume: 285 Pages: 34793-34802

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22380185
  • [Journal Article] ニトリルヒドラターゼの新しい成熟化機構の発見2010

    • Author(s)
      橋本義輝、小林達彦
    • Journal Title

      バイオサイエンスとインダストリー 65

      Pages: 113-116

    • NAID

      10026195063

    • Data Source
      KAKENHI-PROJECT-21658026
  • [Journal Article] Novel isonitrile hydratase involved in isonitrile metabolism2010

    • Author(s)
      Sato, H., Hashimoto, Y., Fukatsu, H. and Kobayashi, M
    • Journal Title

      J. Biol. Chem

      Volume: 285 Pages: 34793-34802

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19208008
  • [Journal Article] High-level expression of a novel amine-synthesizing enzyme, N-substituted formamide deformylase, in Streptomyces with a strong protein expression system2005

    • Author(s)
      Fukatsu, H., Herai, S., Hashimoto, Y., Maseda, H., Higashibata, H., Kobayashi, M.
    • Journal Title

      Protein Expr.Purif. 40

      Pages: 212-219

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14360047
  • [Journal Article] Optimum culture conditions for the production of N-substituted formamide deformylase by Arthrobacter pascens F1642005

    • Author(s)
      Fukatsu, H., Goda, M., Hashimoto, Y., Higashibata, H., Kobayashi, M.
    • Journal Title

      Biosci.Biotech.Biochem. 69

      Pages: 228-230

    • NAID

      130000030579

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14360047
  • [Journal Article] Identification of crucial histidines involved in carbon-nitrogen triple bond synthesis by aldoxime dehydratase2004

    • Author(s)
      Konishi, K., Ishida, K., Oinuma, K-I., Ohta, T., Hashimoto, Y., Higashibata, H., Kitagawa, T., Kobayashi, M.
    • Journal Title

      J.Biol.Chem. 279

      Pages: 47619-47625

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14360047
  • [Journal Article] Amine-synthesizing enzyme N-substituted formamide deformylase : Screening, purification, characterization and gene cloning2004

    • Author(s)
      Fukatsu, H., Hashimoto, Y., Goda, M., Higashibata, H., Kobayashi, M.
    • Journal Title

      Proc.Natl.Acad.Sci.USA 101

      Pages: 13726-13731

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14360047
  • [Journal Article] Novel aldoxime dehydratase involved in carbon-nitrogen triple bond synthesis of Pseudomonas chlororaphis B23 : Sequencing, gene expression, purification and characterization2003

    • Author(s)
      Oinuma, K-I., Hashimoto, Y., Konishi, K., Goda, M., Noguchi, T., Higashibata, H., Kobayashi, M.
    • Journal Title

      J.Biol.Chem. 278

      Pages: 29600-29608

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14360047
  • [Journal Article] Novel aldoxime dehydratase involved in carbon-nitrogen triple bond synthesis of Pseudomonas chlororaphis B23: Sequencing, gene expression, purification and characterization2003

    • Author(s)
      Oinuma, K-I., Hashimoto, Y., Konishi, K., Goda, M., Noguchi, T., Higashibata, H., Kobayashi, M.
    • Journal Title

      J. Biol. Chem. 278

      Pages: 29600-29608

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14380321
  • [Journal Article] A novel lipase from Pseudomonas fluorescens HU380 : Gene cloning, overproduction, renaturation-activation, two-step purification and characterization2003

    • Author(s)
      Kojima, Y., Kobayashi, M., Shimizu, S.
    • Journal Title

      J.Biosci.Bioeng. 96

      Pages: 242-249

    • NAID

      110002665185

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14360047
  • [Journal Article] Novel aldoxime dehydratase involved in carbon-nitrogen triple bond synthesis of Pseudomonas cholororaphis B23:Sequencing, gene expression, purification and characterization2003

    • Author(s)
      Oinuma, K-I., Hashimoto, Y., Konishi, K., Goda, M., Noguchi, T., Higashibata, H., Kobayashi, M.
    • Journal Title

      J.Biol.Chem. 278

      Pages: 29600-29608

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14380321
  • [Journal Article] Isonitrile hydratase from Pseudomonas putida N19-2 : Cloning, sequencing, gene expression, and identification of its active amino acid residue2002

    • Author(s)
      Goda, M., Hashimoto, Y., Takase M., Herai, S., Iwahara, Y., Higashibata, H., Kobayashi, M.
    • Journal Title

      J.Biol.Chem. 277

      Pages: 45860-45865

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14360047
  • [Journal Article] Site-directed mutagenesis for cysteine residues of cobalt-containing nitrile hydratase2002

    • Author(s)
      Hashimoto, Y., Sasaki, S., Herai.S., Oinuma, K,.Shimizu, S., Kobayashi, M.
    • Journal Title

      J.Inorg.Biochem. 91

      Pages: 70-77

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14360047
  • [Presentation] 土壌微生物におけるC-配糖体代謝の初発酵素反応2021

    • Author(s)
      渡辺 聖実、堀 早苗、寺下 柚子、橋本 義輝、熊野 匠人、小林 達彦
    • Organizer
      日本農芸化学会2021年度大会
    • Data Source
      KAKENHI-PLANNED-19H05687
  • [Presentation] C-配糖体代謝酵素の探索と解析2021

    • Author(s)
      堀 早苗、寺下 柚子、熊野 匠人、橋本 義輝、小林 達彦
    • Organizer
      日本農芸化学会2021年度大会
    • Data Source
      KAKENHI-PLANNED-19H05687
  • [Presentation] 鉄型ニトリルヒドラターゼの翻訳後活性化アクセサリータンパク質の解析2020

    • Author(s)
      橋本 義輝、宇部 優子、土居志織、熊野 匠人、小林 達彦
    • Organizer
      日本農芸化学会大会
    • Data Source
      KAKENHI-PROJECT-17H03962
  • [Presentation] 鉄型ニトリルヒドラターゼの翻訳後活性化因子の解析2019

    • Author(s)
      橋本 義輝、宇部 優子、熊野 匠人、小林 達彦
    • Organizer
      日本農芸化学会大会
    • Data Source
      KAKENHI-PROJECT-17H03962
  • [Presentation] Adenylate-forming superfamily酵素における新規ペプチド/アミド合成の反応機構解析2016

    • Author(s)
      橋本 義輝、安部 智子、熊野 匠人、荘 葉、葛 寅、小林 達彦
    • Organizer
      2016年度日本農芸化学会大会
    • Place of Presentation
      札幌コンベンションセンター、北海道・札幌市
    • Data Source
      KAKENHI-PROJECT-23228002
  • [Presentation] ニトリル前駆体アナログの微生物代謝2016

    • Author(s)
      石上 佳奈、橋本 義輝、熊野 匠人、小林 達彦
    • Organizer
      2016年度日本農芸化学会大会
    • Place of Presentation
      札幌コンベンションセンター、北海道・札幌市
    • Data Source
      KAKENHI-PROJECT-23228002
  • [Presentation] 枯草菌細胞壁合成に関与する酵素による新規ペプチド合成反応における反応機構解析2016

    • Author(s)
      安部 智子、橋本 義輝、荘 葉、熊野 匠人、葛 寅、小林 達彦
    • Organizer
      2016年度日本農芸化学会大会
    • Place of Presentation
      札幌コンベンションセンター、北海道・札幌市
    • Data Source
      KAKENHI-PROJECT-23228002
  • [Presentation] New synthetic formation of a carbon-nitrogen bond by unique enzyme function2015

    • Author(s)
      Michihiko Kobayashi
    • Organizer
      BIT’s 6th Annual Symposium of Enzyme & Biocatalysis 2015
    • Place of Presentation
      南京・中国
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23228002
  • [Presentation] アルドキシム脱水酵素の多機能性2015

    • Author(s)
      山田 優駿、橋本 義輝、熊野 匠人、小林 達彦
    • Organizer
      BMB2015(第 38回日本分子生物学会年会、第 88回日本生化学会大会 合同大会)
    • Place of Presentation
      神戸ポートアイランド、兵庫県・神戸市
    • Data Source
      KAKENHI-PROJECT-23228002
  • [Presentation] 微生物代謝および酵素の分子機構と機能開発2015

    • Author(s)
      小林 達彦
    • Organizer
      2015年度日本農芸化学会大会 日本農芸化学会賞受賞講演
    • Place of Presentation
      岡山県岡山市、岡山大学
    • Year and Date
      2015-03-26
    • Invited
    • Data Source
      KAKENHI-PROJECT-23228002
  • [Presentation] ニトリル合成酵素の多機能性2015

    • Author(s)
      山田 優駿、橋本 義輝、熊野 匠人、小林 達彦
    • Organizer
      2015年度日本農芸化学会大会
    • Place of Presentation
      岡山県岡山市、岡山大学
    • Year and Date
      2015-03-29
    • Data Source
      KAKENHI-PROJECT-23228002
  • [Presentation] Microbial degradation of an analog of nitrile precursor2015

    • Author(s)
      Yoshiteru Hashimoto, Suguru Ohsuka and Michihiko Kobayashi
    • Organizer
      2015 International Symposium on New Frontiers in Microbiology and Biotechnology
    • Place of Presentation
      無錫、中国
    • Year and Date
      2015-01-12
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23228002
  • [Presentation] 枯草菌細胞壁合成に関与する酵素を用いたペプチド合成の基質特異性2014

    • Author(s)
      荘 葉、橋本 義輝、安部 智子、葛 寅、熊野 匠人、小林 達彦
    • Organizer
      2014年度日本農芸化学会大会
    • Place of Presentation
      東京、明治大学
    • Year and Date
      2014-03-28
    • Data Source
      KAKENHI-PROJECT-23228002
  • [Presentation] Unique reaction of carbon-nitrogen triple bond synthetic enzyme2014

    • Author(s)
      Masatoshi Yamada, Yoshiteru Hashimoto, Takuto Kumano and Michihiko Kobayashi
    • Organizer
      2014 International Symposium on New Frontiers in Microbiology and Biotechnology
    • Place of Presentation
      Wuxi, China
    • Year and Date
      2014-03-14
    • Data Source
      KAKENHI-PROJECT-23228002
  • [Presentation] 枯草菌細胞壁合成に関与する酵素の基質特異性解析2014

    • Author(s)
      橋本 義輝、荘 葉、安部 智子、葛 寅、熊野 匠人、小林 達彦
    • Organizer
      第87回日本生化学会大会
    • Place of Presentation
      京都府京都市、国立京都国際会館
    • Year and Date
      2014-10-18
    • Data Source
      KAKENHI-PROJECT-23228002
  • [Presentation] Enzymatic dipeptide synthesis2014

    • Author(s)
      T.Abe,Y.Hashimoko,Y.Zhuang,Y.Ge,T.Kumano,M.Kobayashi
    • Organizer
      FEBS EMBO 2014 Conference
    • Place of Presentation
      Paris, France
    • Year and Date
      2014-09-09
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23228002
  • [Presentation] ニトリル前駆体アナログ分解菌の培養条件検討2014

    • Author(s)
      大須賀 勝、橋本 義輝、熊野 匠人、小林 達彦
    • Organizer
      第87回日本生化学会大会
    • Place of Presentation
      京都府京都市、国立京都国際会館
    • Year and Date
      2014-10-18
    • Data Source
      KAKENHI-PROJECT-23228002
  • [Presentation] Substrate specificity in peptide synthetic reaction2014

    • Author(s)
      Y.Hashimoto,T.Abe,Y.Zhuang,Y.Ge,T.Kumano,M.Kobayashi
    • Organizer
      FEBS EMBO 2014 Conference
    • Place of Presentation
      Paris, France
    • Year and Date
      2014-09-09
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23228002
  • [Presentation] ニトリル前駆体アナログ分解菌のスクリーニング2013

    • Author(s)
      大須賀 勝、橋本 義輝、熊野 匠人、小林 達彦
    • Organizer
      第86回日本生化学会大会
    • Place of Presentation
      横浜、パシフィコ横浜
    • Year and Date
      2013-09-13
    • Data Source
      KAKENHI-PROJECT-23228002
  • [Presentation] アルドキシムデヒドラターゼの立体構造と反応機構解析2013

    • Author(s)
      野村 純平、橋本 博、太田 雄大、橋本 義輝、和田 浩一、成田 吉徳、老沼 研一、山田 優駿、小林 達彦
    • Organizer
      第86回日本生化学会大会
    • Place of Presentation
      横浜、パシフィコ横浜
    • Year and Date
      2013-09-11
    • Data Source
      KAKENHI-PROJECT-23228002
  • [Presentation] Microbial nitrile-synthetic enzyme involved in C-N triple bond formation: Unique function and reaction2013

    • Author(s)
      Junpei Nomura,Hiroshi Hashimoto,Takehiro Ohta,Yoshiteru Hashimoto and Michihiko Kobayashi
    • Organizer
      BioMicroWorld 2013
    • Place of Presentation
      Madrid, Spain
    • Year and Date
      2013-10-03
    • Data Source
      KAKENHI-PROJECT-23228002
  • [Presentation] Nitrile-synthetic enzyme involved in the formation of a carbon-nitrogen triple bond2013

    • Author(s)
      M.Kobayashi, J.Nomura and Y.Hashimoto
    • Organizer
      Experimental Biology 2013
    • Place of Presentation
      Boston, USA
    • Year and Date
      2013-04-23
    • Data Source
      KAKENHI-PROJECT-23228002
  • [Presentation] Unique heme-containing enzyme involved in formation of carbon-nitrogen triple bond: Expression, structural and mechanistic understanding and the potential for nitrile synthesis2013

    • Author(s)
      Junpei Nomura,Hiroshi Hashimoto,Takehiro Ohta,Yoshiteru Hashimoto, Michihiko Kobayashi
    • Organizer
      Enzyme Engineering XXII
    • Place of Presentation
      Toyama, Japan
    • Year and Date
      2013-09-26
    • Data Source
      KAKENHI-PROJECT-23228002
  • [Presentation] 枯草菌細胞壁合成に関与する酵素を利用したオリゴペプチド合成2013

    • Author(s)
      荘 葉、橋本 義輝、安部 智子、熊野 匠人、小林 達彦
    • Organizer
      第86回日本生化学会大会
    • Place of Presentation
      横浜、パシフィコ横浜
    • Year and Date
      2013-09-13
    • Data Source
      KAKENHI-PROJECT-23228002
  • [Presentation] 炭素-窒素3重結合形成に関わる酵素の構造機能解析2013

    • Author(s)
      小林 達彦
    • Organizer
      第86回日本生化学会大会
    • Place of Presentation
      横浜、パシフィコ横浜
    • Year and Date
      2013-09-13
    • Data Source
      KAKENHI-PROJECT-23228002
  • [Presentation] Unique enzyme reaction involved in the synthesis of a carbon-nitrogen bond2013

    • Author(s)
      Michihiko Kobayashi
    • Organizer
      2013 Annual Meeting of Society for Industrial Microbiology & Biotechnology (SIMB
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2013-08-12
    • Invited
    • Data Source
      KAKENHI-PROJECT-23228002
  • [Presentation] Arthrobacter F164株から発見した新規イソニトリルヒドラターゼ2011

    • Author(s)
      佐藤太祐、橋本義輝、小林達彦
    • Organizer
      日本農芸化学会大会
    • Place of Presentation
      京都女子大学
    • Year and Date
      2011-03-27
    • Data Source
      KAKENHI-PROJECT-22380185
  • [Presentation] アクリルアミド工業酵素のユニークな成熟化機構2011

    • Author(s)
      橋本義輝、崔天蔚、周哲敏、小林達彦
    • Organizer
      日本農芸化学会大会
    • Place of Presentation
      京都女子大学
    • Year and Date
      2011-03-27
    • Data Source
      KAKENHI-PROJECT-22658033
  • [Presentation] 新規イソニトリルヒドラターゼの生理的機能の解析2010

    • Author(s)
      佐藤太祐、橋本義輝、小林達彦
    • Organizer
      BMB2010
    • Place of Presentation
      神戸ポートアイランド
    • Year and Date
      2010-12-07
    • Data Source
      KAKENHI-PROJECT-22380185
  • [Presentation] "Self-Subunit Swapping"シャペロンの新たな2つの機能2010

    • Author(s)
      橋本義輝、周哲敏、小林達彦
    • Organizer
      日本農芸化学会大会
    • Place of Presentation
      東京
    • Year and Date
      2010-03-29
    • Data Source
      KAKENHI-PROJECT-21658026
  • [Presentation] 微生物酵素のユニークな生成機構:新規翻訳後修飾機構の発見2010

    • Author(s)
      周哲敏、崔天蔚、橋本義輝、小林達彦
    • Organizer
      日本農芸化学会関東支部2010年度第1回支部例会
    • Place of Presentation
      筑波大学
    • Year and Date
      2010-07-17
    • Data Source
      KAKENHI-PROJECT-22658033
  • [Presentation] Microbial nitrile metabolism : from biochemical and genetic studies toindustrial application2010

    • Author(s)
      Michihiko Kobayashi
    • Organizer
      International Symposium on New Frontiers in Microbioiogy and Biotechnology
    • Place of Presentation
      無錫、中国
    • Year and Date
      2010-09-28
    • Data Source
      KAKENHI-PROJECT-22658033
  • [Presentation] Arthrobacter属放線菌由来新規イソニトリルヒドラターゼと既知イソニトリルヒドラターゼとの比較2010

    • Author(s)
      佐藤太祐、橋本義輝、小林達彦
    • Organizer
      日本放線菌学会大会
    • Place of Presentation
      東邦大学
    • Year and Date
      2010-09-02
    • Data Source
      KAKENHI-PROJECT-22380185
  • [Presentation] ニトリルヒドラターゼの翻訳後成熟化中間体の発見2010

    • Author(s)
      橋本義輝、崔天蔚、周哲敏、小林達彦
    • Organizer
      BMB2010神戸
    • Place of Presentation
      神戸ポートアイランド
    • Year and Date
      2010-12-10
    • Data Source
      KAKENHI-PROJECT-22658033
  • [Presentation] N≡C結合開裂酵素に関する研究2010

    • Author(s)
      佐藤太祐、橋本義輝、小林達彦
    • Organizer
      酵素工学研究会
    • Place of Presentation
      東京大学
    • Year and Date
      2010-11-19
    • Data Source
      KAKENHI-PROJECT-22380185
  • [Presentation] Discovery of a novel isonitrile hydratase from Arthrobacter2010

    • Author(s)
      H.Sato, Y.Hashimoto, M.Kobayashi.
    • Organizer
      International Symposium on New Frontiers in Microbiology and Biotechnology
    • Place of Presentation
      無錫、中国
    • Year and Date
      2010-09-28
    • Data Source
      KAKENHI-PROJECT-22380185
  • [Presentation] Arthrobacter属放線菌由来の新規イソニトリルヒドラターゼの解析2010

    • Author(s)
      佐藤太祐、橋本義輝、小林達彦
    • Organizer
      日本農芸化学会大会
    • Place of Presentation
      東京大学駒場キャンパス
    • Year and Date
      2010-03-29
    • Data Source
      KAKENHI-PROJECT-19208008
  • [Presentation] 微生物のユニークかっ高性能な機能:遺伝子高度発現系の開発と新規翻訳後修飾機構の発見2010

    • Author(s)
      Zhemin Zhou, 橋本義輝, Tianwei Cui, 小林達彦
    • Organizer
      BMB2010神戸
    • Place of Presentation
      神戸ポートアイランド
    • Year and Date
      2010-12-10
    • Data Source
      KAKENHI-PROJECT-22658033
  • [Presentation] Arthrobacter属放線菌由来の新規イソニトリルヒドラターゼの解析2010

    • Author(s)
      佐藤太祐, 橋本義輝, 小林達彦
    • Organizer
      日本農芸化学会大会
    • Place of Presentation
      東京
    • Year and Date
      2010-03-29
    • Data Source
      KAKENHI-PROJECT-19208008
  • [Presentation] Novel isonitrile hydratase involved in isonitrile metabolism in Arthrobacter sp2010

    • Author(s)
      H.Sato, Y.Hashimoto, M.Kobayashi.
    • Organizer
      SIM 2010 Annual Meeting
    • Place of Presentation
      サンフランシスコ, USA
    • Year and Date
      2010-08-02
    • Data Source
      KAKENHI-PROJECT-22380185
  • [Presentation] Novel post-translational maturation of high-molecular-mass nitrile hydratase from the industrial strain, Rhodococcus rhododarous J12010

    • Author(s)
      Y.Hashimoto, Z.Zhou, T.Cui, H.Mina, M.Kobayashi
    • Organizer
      SIM 2010 Annual Meeting
    • Place of Presentation
      サンフランシスコ,USA
    • Year and Date
      2010-08-02
    • Data Source
      KAKENHI-PROJECT-22658033
  • [Presentation] Arthrobacter pascens F164株由来イソニトリルヒドラターゼの精製2009

    • Author(s)
      佐藤太祐, 橋本義輝, 深津寛, 小林達彦
    • Organizer
      日本農芸化学会
    • Place of Presentation
      福岡
    • Year and Date
      2009-03-29
    • Data Source
      KAKENHI-PROJECT-19208008
  • [Presentation] 新規イソニトリルヒドラターゼの発見と諸性質の解析2009

    • Author(s)
      佐藤太祐, 橋本義輝, 深津寛, 小林達彦
    • Organizer
      日本生化学会大会
    • Place of Presentation
      神戸
    • Year and Date
      2009-10-23
    • Data Source
      KAKENHI-PROJECT-19208008
  • [Presentation] Unique function of the enzyme involved in isonitrile metablism-A new synthetic route to N-benzylamides-2009

    • Author(s)
      M. Kobayashi, T. Sakashita, H. Fukatsu, and Y. Hashimoto
    • Organizer
      Biochemical Engineering XVI
    • Place of Presentation
      バーリントン(Burlington) USA
    • Year and Date
      2009-07-08
    • Data Source
      KAKENHI-PROJECT-19208008
  • [Presentation] Arthrobacter属放線菌由来イソニトリル分解酵素の諸性質の解析2009

    • Author(s)
      佐藤太祐, 橋本義輝, 深津寛, 小林達彦
    • Organizer
      日本放線菌学会
    • Place of Presentation
      秋田
    • Year and Date
      2009-07-16
    • Data Source
      KAKENHI-PROJECT-19208008
  • [Presentation] Rhodococcus rhodochrous J1菌由来L-Nhaseの翻訳後成熟化に関する研究2009

    • Author(s)
      周哲敏、橋本義輝、小林達彦
    • Organizer
      日本放線菌学会
    • Place of Presentation
      秋田
    • Year and Date
      2009-07-16
    • Data Source
      KAKENHI-PROJECT-21658026
  • [Presentation] Biotransformation of benzylamine to N-benzylformamide2009

    • Author(s)
      T.Sakashita, Y. Hashimoto, H. Fukatsu, and M. Kobayashi
    • Organizer
      109^<th> ASM General Meeting
    • Place of Presentation
      ペンシルバニアUSA
    • Year and Date
      2009-05-18
    • Data Source
      KAKENHI-PROJECT-19208008
  • [Presentation] 放線菌におけるニトリル関連化合物代謝の応用酵素学的研究2009

    • Author(s)
      小林達彦
    • Organizer
      日本放線菌学会
    • Place of Presentation
      秋田
    • Year and Date
      2009-07-16
    • Data Source
      KAKENHI-PROJECT-21658026
  • [Presentation] Arthrobacter属放線菌由来イソニトリル分解酵素の諸性質の解析2009

    • Author(s)
      佐藤太祐、橋本義輝、深津寛、小林達彦
    • Organizer
      日本放線菌学会
    • Place of Presentation
      秋田ビューホテル
    • Year and Date
      2009-07-16
    • Data Source
      KAKENHI-PROJECT-19208008
  • [Presentation] 放線菌におけるニトリル関連化合物代謝の応用酵素学的研究2009

    • Author(s)
      小林達彦
    • Organizer
      日本放線菌学会
    • Place of Presentation
      秋田
    • Year and Date
      2009-07-16
    • Data Source
      KAKENHI-PROJECT-19208008
  • [Presentation] 新規イソニトリルヒドラターゼの発見と諸性質の解析2009

    • Author(s)
      佐藤太祐、橋本義輝、深津寛、小林達彦
    • Organizer
      日本生化学会大会
    • Place of Presentation
      神戸ポートアイランド
    • Year and Date
      2009-10-23
    • Data Source
      KAKENHI-PROJECT-19208008
  • [Presentation] 3つの機能を特つシャペロンの発見2009

    • Author(s)
      橋本義輝、周哲敏、小林達彦
    • Organizer
      日本生化学会大会
    • Place of Presentation
      神戸
    • Year and Date
      2009-10-22
    • Data Source
      KAKENHI-PROJECT-21658026
  • [Presentation] "Self-Subunit Swapping"に関わるChaperoneタンパク質の新たな機能2009

    • Author(s)
      橋本義輝、周哲敏、小林達彦
    • Organizer
      日本放線菌学会
    • Place of Presentation
      秋田
    • Year and Date
      2009-07-16
    • Data Source
      KAKENHI-PROJECT-21658026
  • [Presentation] N-置換ホルムアミド分解酵素の逆反応によるN-置換有機酸アミドの生成2009

    • Author(s)
      坂下俊秀, 橋本義輝, 深津寛, 小林達彦
    • Organizer
      日本農芸化学会
    • Place of Presentation
      福岡
    • Year and Date
      2009-03-29
    • Data Source
      KAKENHI-PROJECT-19208008
  • [Presentation] Degradation of isonitrile by isonitrile hydratase coupled with N-substituted formamide deformylase in Arthrobacter pascens2008

    • Author(s)
      H. Sato, Y. Hashimoto, H. Fukatsu and M. Kobayashi
    • Organizer
      FEBS & IUBMB
    • Place of Presentation
      アテネ
    • Year and Date
      2008-07-03
    • Data Source
      KAKENHI-PROJECT-19208008
  • [Presentation] 放線菌のN-置換ホルムアミド分解酵素の逆反応解析2008

    • Author(s)
      坂下俊秀、深津寛、橋本義輝、小林達彦
    • Organizer
      放線菌学会
    • Place of Presentation
      山梨
    • Year and Date
      2008-07-10
    • Data Source
      KAKENHI-PROJECT-19208008
  • [Presentation] Arthrobacter pascensF164株由来イソニトリルヒドラターゼの最適発現条件2008

    • Author(s)
      佐藤 太祐、深津 寛、橋本 義輝、小林 達彦
    • Organizer
      日本農芸化学会
    • Place of Presentation
      名古屋
    • Year and Date
      2008-03-28
    • Data Source
      KAKENHI-PROJECT-19208008
  • [Presentation] Arthrobacter属放線菌のイソニトリル分解酵素の誘導発現の検討2008

    • Author(s)
      佐藤太祐, 深津寛, 橋本義輝, 小林達彦
    • Organizer
      日本放線菌学会
    • Place of Presentation
      山梨
    • Year and Date
      2008-07-10
    • Data Source
      KAKENHI-PROJECT-19208008
  • [Presentation] Arthrobacter pascens F164株由来イソニトリルヒドラターゼの最適発現条件2008

    • Author(s)
      佐藤太祐, 深津寛, 橋本義輝, 小林達彦
    • Organizer
      日本農芸化学会大会
    • Place of Presentation
      名古屋
    • Year and Date
      2008-03-28
    • Data Source
      KAKENHI-PROJECT-19208008
  • [Presentation] 放線菌のN-置換ホルムアミド分解酵素の逆反応解析2008

    • Author(s)
      坂下俊秀, 深津寛, 橋本義輝, 小林達彦
    • Organizer
      日本放線菌学会
    • Place of Presentation
      山梨
    • Year and Date
      2008-07-10
    • Data Source
      KAKENHI-PROJECT-19208008
  • [Presentation] New Enzymes involved in isonitrile degradation2008

    • Author(s)
      M. Kobayashi, M. Goda, H. Fukatsu and Y. Hashimoto
    • Organizer
      i-Bio-2008 World Congress
    • Place of Presentation
      中国杭州
    • Year and Date
      2008-05-18
    • Data Source
      KAKENHI-PROJECT-19208008
  • [Presentation] Arthrobacter属放線菌のイソニトリル分解酵素の誘導発現の検討2008

    • Author(s)
      佐藤太祐、深津寛、橋本義輝、小林達彦
    • Organizer
      放線菌学会
    • Place of Presentation
      山梨
    • Year and Date
      2008-07-10
    • Data Source
      KAKENHI-PROJECT-19208008
  • [Presentation] Degradation of isonitrile by isonitrile hydratase coupled with N-substituted formamide deformylase in Artihrobacter pascens2008

    • Author(s)
      H. Sato, Y. Hashimoto, H. Fukatsu and M. Kobayashi
    • Organizer
      FEBS&IUBMB
    • Place of Presentation
      アテネ
    • Year and Date
      2008-07-03
    • Data Source
      KAKENHI-PROJECT-19208008
  • [Presentation] New Enzymes Involved in Isonitrile Degradation2008

    • Author(s)
      Michihiko Kobayashi, Masahiko Goda, Hiroshi Fukatsu and Yoshiteru Hashimoto
    • Place of Presentation
      中国杭州
    • Year and Date
      2008-05-18
    • Data Source
      KAKENHI-PROJECT-19208008
  • [Presentation] Microbial nitrile metabolism: Regulation and utilization

    • Author(s)
      Michihiko Kobayashi
    • Organizer
      Society for Industrial Microbiology 61st Annual Meeting (SIM)
    • Place of Presentation
      New Orleans,USA
    • Invited
    • Data Source
      KAKENHI-PROJECT-23228002
  • [Presentation] Aldoxime dehydratase: Crystal structure and catalytic mechanism involved in carbon-nitrogen triple bond synthesis

    • Author(s)
      Yoshiteru Hashimoto, Junpei Nomura, Hiroshi Hashimoto, Takehiro Ohta, Koichi Wada, Yoshinori Naruta, Ken-Ichi Oinuma & Michihiko Kobayashi
    • Organizer
      2013 International Symposium on New Frontiers in Microbiology and Biotechnology
    • Place of Presentation
      Wuxi, China
    • Data Source
      KAKENHI-PROJECT-23228002
  • [Presentation] New isonitrile hydratase from Arthrobacter: Characterization and identification of the active site

    • Author(s)
      Hiroyoshi Sato, Yoshiteru Hashimoto, and Michihiko Kobayashi
    • Organizer
      Internationar Union of Microbiological Societies 2011 Congress (IUMS 2011 Congress)
    • Place of Presentation
      札幌、札幌コンベンションセンター
    • Data Source
      KAKENHI-PROJECT-23228002
  • [Presentation] 新規イソニトリルヒドラターゼの諸性質と活性残基の同定

    • Author(s)
      佐藤 太祐、橋本 義輝、小林 達彦
    • Organizer
      84回 生化学会大会
    • Place of Presentation
      京都、国立京都国際会館
    • Data Source
      KAKENHI-PROJECT-23228002
  • [Presentation] Microbial cleavage of nitrogen-carbon triple bond: Metabolism and enzyme

    • Author(s)
      Hiroyoshi Sato, Yoshiteru Hashimoto and Michihiko Kobayashi
    • Organizer
      American Society for Microbiology 111th General Meeting
    • Place of Presentation
      New Orleans, USA
    • Data Source
      KAKENHI-PROJECT-23228002
  • [Presentation] Diverse metabolism of toxic isonitrile compounds and the degrading enzymes

    • Author(s)
      Michihiko Kobayashi
    • Organizer
      2012 Annual meeting, Society for Industrial Microbiology & Biotechnology
    • Place of Presentation
      Washington,DC, USA
    • Invited
    • Data Source
      KAKENHI-PROJECT-23228002
  • [Presentation] Unique enzyme reactions involved in the formation of a carbon-nitrogen bond

    • Author(s)
      Michihiko Kobayashi
    • Organizer
      Enzyme Engineering XXI
    • Place of Presentation
      Colorado,USA
    • Invited
    • Data Source
      KAKENHI-PROJECT-23228002
  • [Presentation] シュードモナス属細菌由来ニトリル合成酵素の変異体解析

    • Author(s)
      野村 純平、橋本 義輝、小林 達彦
    • Organizer
      84回 生化学会大会
    • Place of Presentation
      京都、国立京都国際会館
    • Data Source
      KAKENHI-PROJECT-23228002
  • [Presentation] ニトリル合成酵素の変異体構築および諸性質の解析

    • Author(s)
      野村 純平、橋本 義輝、小林 達彦
    • Organizer
      2012年度日本農芸化学会
    • Place of Presentation
      京都、京都女子大学
    • Data Source
      KAKENHI-PROJECT-23228002
  • [Presentation] Unique biogenesis of carbon-nitrogen-cleaving enzyme harnessing a new mechanism

    • Author(s)
      Michihiko Kobayashi, Z. Zhou & Yoshiteru Hashimoto
    • Organizer
      2012 Annual meeting, American Society for Biochemistry and Molecular Biology
    • Place of Presentation
      San Diego, USA
    • Invited
    • Data Source
      KAKENHI-PROJECT-23228002
  • [Presentation] 枯草菌細胞壁合成に関与する酵素を用いた新規ペプチド合成法

    • Author(s)
      荘 葉、橋本 義輝、安部 智子、葛 寅、熊野 匠人、小林 達彦
    • Organizer
      2013年度日本農芸化学会
    • Place of Presentation
      仙台、東北大学
    • Data Source
      KAKENHI-PROJECT-23228002
  • [Presentation] 枯草菌細胞壁合成に関与する酵素の新規アミド結合触媒反応

    • Author(s)
      荘 葉、安部 智子、葛 寅、橋本 義輝、小林 達彦
    • Organizer
      第85回日本生化学会大会
    • Place of Presentation
      福岡、福岡国際会議場・マリンメッセ福岡
    • Data Source
      KAKENHI-PROJECT-23228002
  • [Presentation] Microbial Nitrile-synethetic Metabolism and the Enzyme

    • Author(s)
      Junpei Nomura, Ken-Ichi Oinuma, Yoshiteru Hashimoto & Michihiko Kobayashi
    • Organizer
      American Society for Microbiology 112th General Meeting
    • Place of Presentation
      San Francisco, USA
    • Data Source
      KAKENHI-PROJECT-23228002
  • [Presentation] 新規イソニトリルヒドラターゼの機能解析

    • Author(s)
      佐藤 太祐、橋本 義輝、小林 達彦
    • Organizer
      2012年度日本農芸化学会
    • Place of Presentation
      京都、京都女子大学
    • Data Source
      KAKENHI-PROJECT-23228002
  • [Presentation] 微生物代謝の分子機構と物質生産への機能開発

    • Author(s)
      小林 達彦
    • Organizer
      BioJapan2012
    • Place of Presentation
      横浜、パシフィコ横浜
    • Invited
    • Data Source
      KAKENHI-PROJECT-23228002
  • [Presentation] 微生物と酵素の潜在機能の開拓: 探索と戦略

    • Author(s)
      小林 達彦
    • Organizer
      2012年度日本農芸化学会
    • Place of Presentation
      京都、京都女子大学
    • Data Source
      KAKENHI-PROJECT-23228002
  • [Presentation] Discovery of a novel enzyme involved in cleavage of a nitrogen-carbon triple bond

    • Author(s)
      Hiroyoshi Sato, Yoshiteru Hashimoto, & Michihiko Kobayashi
    • Organizer
      The 12th Japan-China-Korea Joint Symposium on Enzyme Engineering
    • Place of Presentation
      Kanazawa, Japan, Kanazawa Excel Hotel Tokyu
    • Data Source
      KAKENHI-PROJECT-23228002
  • [Presentation] Arthrobacter属放線菌由来新規イソニトリルヒドラターゼの部位特異的変異解析

    • Author(s)
      橋本 義輝、佐藤 太祐、小林 達彦
    • Organizer
      2012年度日本放線菌学会大会
    • Place of Presentation
      東京、府中の森芸術劇場
    • Data Source
      KAKENHI-PROJECT-23228002
  • 1.  SHIMIZU Sakayu (70093250)
    # of Collaborated Projects: 19 results
    # of Collaborated Products: 0 results
  • 2.  HASHIMOTO Yoshiteru (00323254)
    # of Collaborated Projects: 19 results
    # of Collaborated Products: 84 results
  • 3.  KATAOKA Michihiko (90252494)
    # of Collaborated Projects: 13 results
    # of Collaborated Products: 0 results
  • 4.  OGAWA Jun (70281102)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 0 results
  • 5.  HIGASHIBATA Hiroki (20344864)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 6 results
  • 6.  KUMANO Takuto (70585025)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 17 results
  • 7.  GODA Masahiko
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 8.  MASEDA Hideaki (10372343)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 9.  白木 賢太郎 (90334797)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  NAGASAWA Toru (60115904)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  BABA Naomichi (50027075)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  KAMIYA Nobuo (60152865)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  KAWANO Yoshiaki (70321750)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  FURUSE Munenori (50321807)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  NOJIRI Masaki (20333346)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  ODAKA Masafumi (20224248)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  SUGIURA Norio (10302374)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  UTSUMI Motoo (60323250)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  周 哲敏 (50447231)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  山田 秀明 (30027180)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  遠藤 勲 (00087470)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  前川 孝昭 (40015665)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  高谷 直樹 (50282322)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  大津 厳生 (60395655)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  林 久喜 (70251022)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 26.  AKIMOTO Kengo
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  SAKAMOTO Keiji
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  FURUYA Yuji
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  EMDO Ryuichi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  古谷 裕治
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  岡野 邦宏
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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