Matsuoka Masaaki 松岡正明

… Alternative Names

MATSUOKA MASAAKI 松岡正明

MATSUOKA Masaaki 松岡正明

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Researcher Number	70222297
Other IDs
External Links
Affiliation (Current)	2025: 東京医科大学, 医学部, 主任教授
Affiliation (based on the past Project Information) *help	2016 – 2017: 東京医科大学, 医学部, 主任教授 2015: 東京医科大学, 医学部, 教授 2009 – 2013: Tokyo Medical University, 医学部, 教授 2010: Keio University, 医学部, 主任教授 2007 – 2008: Keio University, School of Medicine, Associate Professor 1999 – 2006: 慶應義塾大学, 医学部, 助教授
Review Section/Research Field	Principal Investigator General pharmacology / Pathological medical chemistry / Obstetrics and gynecology / Experimental pathology / Biological Sciences / Psychiatric science Except Principal Investigator Neurology / General pharmacology / Neurology / Biological Sciences / Pediatrics
Keywords	Principal Investigator ヒューマニン / アルツハイマー病 / 神経細胞死 / TGFbeta2 / 細胞死 / ARF / BCL6 / CR / p53 / ik3-2 … More / ik3-1 / CLSP / Humanin / Cdc7 / 筋萎縮性側索硬化症 / アルツハイマー病抑制因子 / 薬理学 / 脳神経疾患 / シグナル伝達 / 神経細胞死抑制因子 / humanin / 非定型的細胞外分泌 / 14-3-3 sigma / 分泌経路 / 細胞外分泌 / 14-3-3 / Defense factor / Colivelin / Neuronal cell death / Alzheimer's disease / 防御因子 / コリベリン / BAX / 造精細胞死 / 男性不妊 / BTBD10 / ALS / 神経変性疾患 / 小胞体ストレス / 癌治療 / 細胞癌化 / cdk3 / cdk2 / 細胞周期停止 / アポトーシス / Bax / αサブユニット / ApoE4 … More Except Principal Investigator アルツハイマー病 / 神経細胞死 / ヒューマニン / Alzheimer's disease / Humanin / RAP / LRP / 細胞内シグナル伝達 / アミロイド前駆体タンパク質 / コリベリン / ADNF / APP / 細胞死 / 神経科学 / Apollon / UNC5C / CLSP / 創薬化学 / 脳脊髄液 / PET / タウ / アミロイド / 糖尿病 / 認知症 / Brain atrooh / Colivelin / Neuronal death / 脳萎縮 / receptor / serine isomerase / dimerization / neurodegenerative disease / βFGF / IGF-I / 生体内発現 / bFGF / IGF-1 / 分泌機構 / 構造機能相関 / HN / Apolipoprotein E3 / α2-macroglobullin / Neuronal Death / Apolipoprotein E4 / 細胞死抑制 / ApoE3 / α2マクログロブリン / ApoE4 / 細胞内シグナル伝 / 治療薬 / 受容体 / サイトカイン / 神経変性疾患 / プレセニリン / アミロイド前駆体蛋白質 / 運動神経細胞死 / ALSマウス / G93A-SOD1 / FALS / 筋萎縮性側索硬化症 / 疾患モデルマウス / ノックイン / Cre-loxP / V642I点変異 / 遺伝子ターゲティング / レチノイン酸 / モノクローナル抗体 / ヒト神経芽細胞腫株 / αシヌクレイン Less

Pathophysiological study of diabetes-related dementia
- Principal Investigator
  
  Hanyu Haruo
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Tokyo Medical University
Analysis of secretory pathway of 14-3-3sigmaPrincipal Investigator
- Principal Investigator
  
  Matsuoka Masaaki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Tokyo Medical University
A novel rescue factor for Alzheimer's diseasePrincipal Investigator
- Principal Investigator
  
  Matsuoka Masaaki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Tokyo Medical University
Identification of Alzheimer's disease-relevant neuronal death inhibiting molecular basis and its application for drug development
- Principal Investigator
  
  HASHIMOTO YUICHI
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Tokyo Medical University
Characterization and clinical application of endogenous Alzheimer's disease-suppressing factorPrincipal Investigator
- Principal Investigator
  
  MATSUOKA Masaaki
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Tokyo Medical University
Humanin-mediated rescue of testicular germ cell apoptosisPrincipal Investigator
- Principal Investigator
  
  MATSUOKA Masaaki
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Tokyo Medical University
Search for neuronal cell death-inhibiting drugs for Alzheimer's disease-relevant signal transduction
- Principal Investigator
  
  HASHIMOTO Yuuichi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Tokyo Medical University
Neuronal death-inhibiting therapy for neurodegenerative diseasePrincipal Investigator
- Principal Investigator
  
  MATSUOKA Masaaki
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Keio University
筋萎縮性側索硬化症発症要因としてのVAPBと小胞体ストレスの解析Principal Investigator
- Principal Investigator
  
  松岡正明
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  General pharmacology
- Research Institution
  Keio University
Investigation on TGFbeta2 involvement in Alzheimer's disease's related neuronal death and Humanin signal transduction as an endogenous anti-Alzheimer's disease's defense factorPrincipal Investigator
- Principal Investigator
  
  MATSUOKA Masaaki
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Keio University
Progress from the endogenous protective factor against Alzheimer's disease
- Principal Investigator
  
  TERASHITA Kenzo
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Keio University
アルツハイマー病抑制因子ヒユーマニンの発癌作用の検討Principal Investigator
- Principal Investigator
  
  松岡正明
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Experimental pathology
- Research Institution
  Keio University
FALS変異SOD1による神経変性に拮抗する新規神経再生因子の作用機序解析
- Principal Investigator
  
  喜多淑子
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Keio University
Elucidation of mechanisms underlying p53-independent growth-suppressive activity for tumor suppressor proteins with p53-activating function.Principal Investigator
- Principal Investigator
  
  MATSUOKA Masaaki
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Keio University
cdk2/cdk3の新しい基質ik3遺伝子群の機能解析Principal Investigator
- Principal Investigator
  
  松岡正明
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Keio University
新規のAPP変異ノックインマウスを用いたアルツハイマー病発症関連遺伝子の探索
- Principal Investigator
  
  KOUYAMA Keisuke
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Neurology
- Research Institution
  Keio University
Detailed characterization of Humanin, a newly identified anti-Alzheimer's disease peptide and potential starting point for development of the first curative therapy for Alzheimer's disease
- Principal Investigator
  
  NISHIMOTO Ikuo
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Neurology
- Research Institution
  KEIO UNIVERSITY
神経細胞におけるアミロイド前駆体蛋白とαシヌクレインの機能の解析
- Principal Investigator
  
  YAMOCHI Tadanori
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Neurology
- Research Institution
  Keio University
レチノイン酸と、神経細胞死誘導性抗APP抗体を併用した神経芽細胞腫の萌芽的治療
- Principal Investigator
  
  西本征央 (西本育夫)
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Pediatrics
- Research Institution
  Keio University
ApoE4の誘導する神経細胞死機構の萌芽的研究Principal Investigator
- Principal Investigator
  
  松岡正明
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Psychiatric science
- Research Institution
  Keio University
Elucidation of the principal mechanism for dementia and identification of anti-dementia genes through the analysis of ApoE4 neurotoxicity
- Principal Investigator
  
  NISHIMOTO Ikuo
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Neurology
- Research Institution
  Keio University

[Book] 神経変性疾患治療の新しい可能性-ヒューマニンの役割をめぐって-2006
- Author(s)
  松岡正明, 西本征央
- Total Pages
  7
- Publisher
  化学と生物
- Data Source
  KAKENHI-PROJECT-17659117
[Book] 神経変性疾患治療の新しい可能性-ヒューマニンの役割をめぐって-2006
- Author(s)
  松岡正明, 西本征央
- Total Pages
  7
- Publisher
  化学と生物
- Data Source
  KAKENHI-PROJECT-18390077
[Book] 神経変性疾患治療の新しい可能性-ヒューマニンの役割をめぐって2006
- Author(s)
  松岡正明, 西本征央
- Publisher
  化学と生物
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390077
[Journal Article] Calmodulin-like skin protein protects against spatial learning impairment in a mouse model of Alzheimer disease2018
- Author(s)
  Shinya Kusakari, Mikiro Nawa, Katsuko Sudo, Masaaki Matsuoka
- Journal Title
  
  Journal of neurochemistry
  
  Volume: 144 Issue: 2 Pages: 218233-218233
- DOI
  10.1111/jnc.14258
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08557, KAKENHI-PROJECT-15K08245, KAKENHI-PROJECT-15H04689
[Journal Article] Calmodulin-like skin protein is downregulated in human cerebrospinal fluids of Alzheimer's disease patients with apolipoprotein E4; a pilot study using postmortem samples.2017
- Author(s)
  Hashimoto Y, Umahara T, Hanyu H, Iwamoto T, Matsuoka M.
- Journal Title
  
  Neurol Res.
  
  Volume: 39 Issue: 9 Pages: 767-772
- DOI
  10.1080/01616412.2017.1335458
- NAID
  130007900286
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04689
[Journal Article] hnRNPA1 autoregulates its own mRNA expression to remain non-cytotoxic.2017
- Author(s)
  Suzuki H, Matsuoka M.
- Journal Title
  
  Molecular and Cellular Biochemistry.
  
  Volume: 427 Issue: 1-2 Pages: 123-131
- DOI
  10.1007/s11010-016-2904-x
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H04689
[Journal Article] An Alzheimer's disease-linked rare mutation potentiates netrin receptor uncoordinated-5C-induced signaling that merges with amyloid β precursor protein signaling.2016
- Author(s)
  Hashimoto Y, Toyama Y, Kusakari S, Nawa M, Matsuoka M.
- Journal Title
  
  J Biol Chem.
  
  Volume: N/A Issue: 23 Pages: 1228212293-1228212293
- DOI
  10.1074/jbc.m115.698092
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H04689, KAKENHI-PROJECT-16K08557
[Journal Article] The Lysosomal Trafficking Transmembrane Protein 106B Is Linked to Cell Death.2016
- Author(s)
  Suzuki H, Matsuoka M.
- Journal Title
  
  J Biol Chem.
  
  Volume: 291 Issue: 41 Pages: 21448-21460
- DOI
  10.1074/jbc.m116.737171
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H04689
[Journal Article] Glycolytic flux controls D-serine synthesis through glyceraldehyde-3-phosphate dehydrogenase in astrocytes.2015
- Author(s)
  Suzuki M, Sasabe J, Miyoshi Y, Kuwasako K, Muto Y, Hamase K, Matsuoka M, Imanishi N, Aiso S.
- Journal Title
  
  Proc Natl Acad Sci U S A.
  
  Volume: 112 Issue: 17
- DOI
  10.1073/pnas.1416117112
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K06982, KAKENHI-PROJECT-15H04689
[Journal Article] Protective effects of Humanin and calmodulin-like skin protein in Alzheimer's disease and broad range of abnormalities.2015
- Author(s)
  Matsuoka M.
- Journal Title
  
  Mol Neurobiol.
  
  Volume: 51 Issue: 3 Pages: 1232-1239
- DOI
  10.1007/s12035-014-8799-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04689
[Journal Article] Secreted calmodulin-like skin protein ameliorates scopolamine-induced memory impairment.2014
- Author(s)
  Hayashi M, Tajima H, Hashimoto Y, Matsuoka M.
- Journal Title
  
  NeuroReport
  
  Volume: not decided
- NAID
  120005407941
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390059
[Journal Article] KCTD20, a relative of BTBD10, is a positive regulator of Akt.2014
- Author(s)
  Nawa M, Matsuoka M
- Journal Title
  
  BMC Biochem
  
  Volume: not decided Issue: 1 Pages: 1-7
- DOI
  10.1186/1471-2091-14-27
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390059, KAKENHI-PROJECT-24790264
[Journal Article] A mutation protective against Alzheimer's disease renders amyloid β precursor protein incapable of mediating neurotoxicity2014
- Author(s)
  Hashimoto Y, Matsuoka M
- Journal Title
  
  J Neurochem
  
  Volume: not decided Issue: 2 Pages: 291-300
- DOI
  10.1111/jnc.12717
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23390059, KAKENHI-PROJECT-25460343
[Journal Article] Apollon/Bruce is upregulated by Humanin.2014
- Author(s)
  4.Hashimoto, Y., Takeshita, Y., Naito, M., Uchino, H. and Matsuoka, M
- Journal Title
  
  Mol Cell Biochem.
  
  Volume: 397 Issue: 1-2 Pages: 147-55
- DOI
  10.1007/s11010-014-2182-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25460084, KAKENHI-PROJECT-25460343
[Journal Article] KCTD20, a relative of BTBD10, is a positive regulator of Akt2013
- Author(s)
  Nawa M, Matsuoka M
- Journal Title
  
  BMC Biochem
  
  Volume: (in press)
- Data Source
  KAKENHI-PROJECT-23390059
[Journal Article] Secreted calmodulin-like skin protein inhibits neuronal death in cell-based Alzheimer's disease models via the heterotrimeric Humanin receptor2013
- Author(s)
  Hashimoto Y, Nawa M, Kurita M, Tokizawa M,Iwamatsu A, Matsuoka M
- Journal Title
  
  Cell Death Dis
  
  Volume: 4 Issue: 3 Pages: 555-555
- DOI
  10.1038/cddis.2013.80
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590247, KAKENHI-PROJECT-23390059, KAKENHI-PROJECT-23659784, KAKENHI-PROJECT-24790264, KAKENHI-PROJECT-25460343
[Journal Article] Secreted calmodulin-like skin protein ameliorates scopolamine-induced memory impairment2013
- Author(s)
  Hayashi M, Tajima H, Hashimoto Y, Matsuoka M
- Journal Title
  
  Neuroreport
- NAID
  120005407941
- Data Source
  KAKENHI-PROJECT-23390059
[Journal Article] Reduced expression of BTBD10 in anterior horn cells with Golgi fragmentation and pTDP-43-positive inclusions in patients with sporadic amyotrophic lateral sclerosis2013
- Author(s)
  Furuta N, Makioka K, Fujita Y, Ikeda M, Takatama M, Matsuoka M, Okamoto K
- Journal Title
  
  Neuropathology
  
  Volume: 33 Issue: 4 Pages: 397-404
- DOI
  10.1111/neup.12010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390059, KAKENHI-PROJECT-23591231, KAKENHI-PROJECT-24591250
[Journal Article] Secreted calmodulin- like skin protein ameliorates scopolamine- induced memory impairment2013
- Author(s)
  Hayashi M, Tajima H, Hashimoto Y, Matsuoka M
- Journal Title
  
  NeuroReport
  
  Volume: (in press)
- NAID
  120005407941
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659784
[Journal Article] Secreted calmodulin-like skin protein ameliorates scopolamine-induced memory impairment.2013
- Author(s)
  Hayashi M, Tajima H, Hashimoto Y, Matsuoka M.
- Journal Title
  
  NeuroReport
  
  Volume: 25 Issue: 9 Pages: 751-735
- DOI
  10.1097/wnr.0b013e328362d9fe
- NAID
  120005407941
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25460343
[Journal Article] The JNK/c-Jun signaling axis contributes to the TDP-43-induced cell death.2013
- Author(s)
  Hiroaki Suzuki and Masaaki Matsuoka
- Journal Title
  
  Molecular and Cellular Biochemistry
  
  Volume: 372 Issue: 1-2 Pages: 241-248
- DOI
  10.1007/s11010-012-1465-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J09347, KAKENHI-PROJECT-23390059
[Journal Article] Secreted calmodulin-like skin protein ameliorates scopolamine-induced memory impairment2013
- Author(s)
  Hayashi M, Tajima H, Hashimoto Y, Matsuoka M
- Journal Title
  
  NeuroReport
  
  Volume: 24
- NAID
  120005407941
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659784
[Journal Article] Secreted calmodulin-like skin protein ameliorates scopolamine-induced memory impairment2013
- Author(s)
  Hayashi M, Tajima H, Hashimoto Y, Matsuoka M
- Journal Title
  
  NeuroReport
  
  Volume: 24
- NAID
  120005407941
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390059
[Journal Article] SH3-binding protein 5 mediates the neuroprotective effect of the secreted bioactive peptide Humanin by inhibiting c-Jun NH2-teminal kinase2013
- Author(s)
  Takeshita Y, Hashimoto Y, Nawa M, Uchino H, Matsuoka M
- Journal Title
  
  J Biol Chem
  
  Volume: 288 Issue: 34 Pages: 24691-24704
- DOI
  10.1074/jbc.m113.469692
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390059, KAKENHI-PROJECT-24790264, KAKENHI-PROJECT-25460343
[Journal Article] The JNK/c-jun signaling axis contributes to the TDP-43-induced cell death2013
- Author(s)
  Suzuki H, Matsuoka M
- Journal Title
  
  Mol Cell Biochem
  
  Volume: 372 Pages: 241-248
- Data Source
  KAKENHI-PROJECT-23390059
[Journal Article] TDP-43 toxicity is mediated by the unfolded protein response-unrelated induction of C/EBP homologous protein expression2012
- Author(s)
  Suzuki H, Matsuoka M
- Journal Title
  
  J Neurosci Res
  
  Volume: 90 Pages: 641-647
- Data Source
  KAKENHI-PROJECT-23390059
[Journal Article] D-amino acid oxidase controls motoneuron degeneration through D-serine2012
- Author(s)
  Sasabe J, Miyoshi Y, Suzuki M, Mita M, Konnno R, Matsuoka M, Hamase K, Aiso S
- Journal Title
  
  Proc Natl Acad Sci USA
  
  Volume: 109 Pages: 627-632
- Data Source
  KAKENHI-PROJECT-23390059
[Journal Article] Neuronal death-inhibiting therapy for Alzheimer's disease2012
- Author(s)
  Matsuoka M
- Journal Title
  
  Nihon Ronen Igakkai Zasshi.
  
  Volume: 49 Pages: 303-306
- NAID
  40019365530
- Data Source
  KAKENHI-PROJECT-23390059
[Journal Article] MOCA is an integrator of the neuronal death signals that are activated by familial Alzheimer's disease-related mutants of amyloid β precursor protein and presenilins2012
- Author(s)
  Tachi N, Hashimoto Y, Matsuoka M
- Journal Title
  
  Biochem J
  
  Volume: 442 Pages: 413-422
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390059
[Journal Article] Overexpression of TDP-43 causes partially p53-dependent G2/M arrest and p53-independent cell death in HeLa cells2012
- Author(s)
  Lee K, Suzuki H, Aiso S, Matsuoka M
- Journal Title
  
  Neurosci Lett
  
  Volume: 506 Pages: 271-276
- NAID
  120005340753
- Data Source
  KAKENHI-PROJECT-23390059
[Journal Article] MOCA is an integrator of the neuronal death signals that are activated by familial Alzheimer's disease-related mutants of amyloid beta precursor protein and presenilins2012
- Author(s)
  Tachi N, Hashimoto Y, Matsuoka M
- Journal Title
  
  Biochem J
  
  Volume: 442 Pages: 413-422
- Data Source
  KAKENHI-PROJECT-23390059
[Journal Article] Reduced expression of BTBD10, an Akt activator, leads to motor neuron death2012
- Author(s)
  Nawa M, Kage-Nakadai E, Aiso S, Okamoto K, Mitani S, Matsuoka M
- Journal Title
  
  Cell Death Differ
  
  Volume: 19 Pages: 1398-1407
- Data Source
  KAKENHI-PROJECT-23390059
[Journal Article] MOCA is an integrator of the neuronal death signals that are activated by familial Alzheimer 's disease-related mutants of amyloid beta precursor protein and presenilin2012
- Author(s)
  Tachi N, Hashimoto Y, Matsuoka M
- Journal Title
  
  Biochem. J
  
  Volume: 442 Issue: 2 Pages: 413-422
- DOI
  10.1042/bj20100993
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590247
[Journal Article] Reduced Expression of BTBD10, an Akt activator, Drives Impairment of Motor Function2012
- Author(s)
  Nawa M, et al
- Journal Title
  
  Cell Death and Differentiation
  
  Volume: (in press) Issue: 8 Pages: 1398-1407
- DOI
  10.1038/cdd.2012.19
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390063, KAKENHI-PROJECT-23390059, KAKENHI-PROJECT-23790256, KAKENHI-PROJECT-24390053, KAKENHI-PROJECT-24790264
[Journal Article] Amyotrophic lateral sclerosis-linked mutant VAPB enhances TDP-43-induced motor neuronal toxicity2011
- Author(s)
  Hiroaki Suzuki
- Journal Title
  
  Journal of Neurochemistry
  
  Volume: VOL.119 Issue: 5 Pages: 1099-1107
- DOI
  10.1111/j.1471-4159.2011.07491.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790261, KAKENHI-PROJECT-23390059
[Journal Article] Caricasole AVSTM2L is a novel secreted antagonist of the neuroprotective peptide Humanin2011
- Author(s)
  Rossini L, Hashimoto Y, Suzuki H, Kurita M, Gianfriddo M, Scali C, Roncarati R, Franceschini D, Pollio G, Trabalzini L, Terstappen GC, Matsuoka M
- Journal Title
  
  FASEB J.
  
  Volume: 25 Issue: 6 Pages: 1983-2000
- DOI
  10.1096/fj.10-163535
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590247
[Journal Article] VSTM2L is a novel secreted antagonist of the neuroprotective peptide Humanin.2011
- Author(s)
  Rossini L, Hashimoto Y, Suzuki H, Kurita M, Gianfriddo M, Scali C, Roncarati R, Franceschini D, Pollio G, Trabalzini L, Terstappen GC, Matsuoka M, Caricasole A.
- Journal Title
  
  FASEB J.
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390072
[Journal Article] TDP-43-induced Death Is Associated with Altered Regulation of BIM and Bcl-xL and Attenuated by Caspase-mediated TDP-43 Cleavage.2011
- Author(s)
  Suzuki H, Lee K, Matsuoka M
- Journal Title
  
  J Biol Chem.
  
  Volume: 286 Pages: 13171-13183
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390072
[Journal Article] VSTM2L IS A NOVEL SECRETED ANTAGONIST OF THE NEUROPROTECTIVE PEPTIDE HUMANIN2011
- Author(s)
  Lara Rossini, Hashimoto Y, Suzuki H, Kurita M, Marco Gianfriddo, Carla Scali, Renza Roncarati, Davide Franceschini, Giuseppe Pollio, Lorenza Trabalzin, Georg C. Terstappen, Matsuoka M, Caricasole A
- Journal Title
  
  FASEB J. (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390072
[Journal Article] TDP-43-induced death is associated with altered regulation of BIM and Bcl-xL and attenuated by caspase-mediated TDP-43 cleavage2011
- Author(s)
  Suzuki H, Lee K, Matsuoka M
- Journal Title
  
  J Biol Chem
  
  Volume: 286 Pages: 13171-13183
- Data Source
  KAKENHI-PROJECT-23390059
[Journal Article] Humanin signal for Alzheimer's disease2011
- Author(s)
  Matsuoka M
- Journal Title
  
  A review.J Alzheimers Dis
  
  Volume: 24 Suppl 2 Pages: 27-32
- Data Source
  KAKENHI-PROJECT-23390059
[Journal Article] TDP-43-induced death is associated with altered regulation of BIM and Bel-xL and attenuated by caspase-mediated TDP-43 cleavage2011
- Author(s)
  Suzuki H, Lee K, Matsuoka M
- Journal Title
  
  J Biol Chem
  
  Volume: 286 Pages: 13171-13183
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390059
[Journal Article] Humanin Signal for Alzheimer's Disease.2011
- Author(s)
  Matsuoka M
- Journal Title
  
  J Alzheimers Dis.
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390072
[Journal Article] TDP-43-induced death is associated with altered regulation of BIM and BCL-XL and attenuated by caspase-mediated TDP-43 cleavage.2011
- Author(s)
  Suzuki H, Lee K, Matsuoka M
- Journal Title
  
  J Biol Chem.(Epub ahead of print)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390072
[Journal Article] Amyotrophic lateral sclerosis-linked mutant VAPB enhances TDP-43-induced motor neuronal toxicity2011
- Author(s)
  Suzuki H, Matsuoka M
- Journal Title
  
  J Neurochem
  
  Volume: 119 Pages: 1099-1107
- Data Source
  KAKENHI-PROJECT-23390059
[Journal Article] Humanin signal for Alzheimer's disease2011
- Author(s)
  Matsuoka M.
- Journal Title
  
  J Alzheimers Dis
  
  Volume: 24Suppl 2 Pages: 27-32
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390059
[Journal Article] VSTM2L is a novel secreted antagonist of the neuroprotective peptide Humanin2011
- Author(s)
  Rossini L, Hashimoto Y, Suzuki H, Kurita M, Gianfriddo M, Scali C, Roncarati R, Franceschini D, Pollio G, Trabalzini L, Terstappen GC, Matsuoka M, Caricasole A
- Journal Title
  
  FASEB J
  
  Volume: 25 Pages: 1983-2000
- Data Source
  KAKENHI-PROJECT-23390059
[Journal Article] Humanin Signal for Alzheimer's Disease2011
- Author(s)
  Matsuoka M
- Journal Title
  
  J Alzheimers Dis.(Epub ahead of print)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390072
[Journal Article] Humanin and the receptors for Humanin.2010
- Author(s)
  Matsuoka M, Hashimoto Y
- Journal Title
  
  Molecular Neurobiology 41
  
  Pages: 22-28
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390072
[Journal Article] Transforming Growth Factor β2 Level is Elevated in Neurons of Alzheimer's Disease's Brains.2010
- Author(s)
  Noguchi M, Nawa M, Okamoto K, Aiso S, Matsuoka M.
- Journal Title
  
  International Journal of Neuroscience 120
  
  Pages: 168-175
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390072
[Journal Article] Immunolocalization of humanin in human sperm and testis.2010
- Author(s)
  Moretti E, Giannerini V, Rossini L, Matsuoka M, Trabalzini L, Collodel G.
- Journal Title
  
  Fertil Steril.
  
  Volume: 94 Pages: 2888-2890
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390072
[Journal Article] TAG-1 is an inhibitor of TGF β 2-induced neuronal death via amyloid β precursor protein2010
- Author(s)
  Tachi N, Hashimoto Y, Nawa M, Matsuoka M.
- Journal Title
  
  Biochemical and Biophysical Research Communications 394
  
  Pages: 119-125
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390072
[Journal Article] Humanin and the receptors for Humanin2010
- Author(s)
  Matsuoka, M., Hashimoto, Y.
- Journal Title
  
  Molecular Neurobiology
  
  Volume: 41 Pages: 22-28
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590247
[Journal Article] Transforming growth factor beta2 level is elevated in nurons of Alzheimer's disease brain.2010
- Author(s)
  Noguchi A, Nawa M, Aiso S, Okamoto K, Matsuoka M
- Journal Title
  
  Int J.Neurosci.
  
  Volume: 120 Pages: 168-175
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390072
[Journal Article] Identification of soluble WSX-1 not as a dominant-negative but as an alternative functional subunit of a receptor for an anti-Alzheimer's diseaserescue factor Humanin.2009
- Author(s)
  Hashimoto Y, Kurita M, Matsuoka M.
- Journal Title
  
  Biochemical and Biophysical Research Communications 389
  
  Pages: 95-99
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390072
[Journal Article] Humanin inhibits neuronal cell death by interacting with a cytokine receptor complex or complexes involving CNTF receptor alfa/WSX-1/gp130.2009
- Author(s)
  Hashimoto Y, Kurita M, Aiso S, Nishimoto I, Matsuoka M.
- Journal Title
  
  Molecular Biology of the Cell 20
  
  Pages: 2864-2873
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390072
[Journal Article] Humanin ; a defender against Alzheimer's disease?2009
- Author(s)
  Matsuoka M.
- Journal Title
  
  Recent Patents in CNS Drug Discov 4
  
  Pages: 37-42
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659063
[Journal Article] Humanin ; a defender against Alzheimer's disease?2009
- Author(s)
  Matsuoka M.
- Journal Title
  
  Recent Patents in CNS Drug Discov 4
  
  Pages: 37-42
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390072
[Journal Article] A novel Akt/PKB-interacting protein promotes cell adhesion and inhibits familial amyotrophic lateral sclerosis-linked mutant SOD1-induced neuronal death via inhibition of PP2A-mediated dephosphorylation of Akt/PKB2008
- Author(s)
  Nawa, M, Kanekura, K, Hashimoto, Y, Aiso, S, Matsuoka, M
- Journal Title
  
  Cell Signal 20
  
  Pages: 493-505
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390077
[Journal Article] Anti-Apoptotic Action of Wnt5a in Dermal Fibroblasts Is Mediated by the PKA Signaling Pathway2008
- Author(s)
  Torii, K, Nishizawa, K, Kawasaki, A, Yamashita, Y, et. al., Matsuoka, M
- Journal Title
  
  Cell Signal 20
  
  Pages: 1256-1266
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390077
[Journal Article] Anti-Apoptotic Action of Wnt5a in Dermal Fibroblasts Is Mediated by the PKA Signaling Pathway2008
- Author(s)
  Torii, K, Nishizawa, K, Kawasaki, A, Yamashita, Y, et. al., Matsuoka, M
- Journal Title
  
  Cell Signal 20
  
  Pages: 1256-1266
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590240
[Journal Article] Nasal ColivelinTreatment Ameliorates Memory Impairment Related to Alzheimer'sDisease.2008
- Author(s)
  Yamada, M, Chiba, T, Sasabe, J, Terashita, K, Aiso, S, Matsuoka, M
- Journal Title
  
  Neuropsychopharmacology (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390077
[Journal Article] Nasal Cohvelin Tleatment Ameliorates Memory Impairment Related to Alzheimer's Disease2008
- Author(s)
  Yamada M, Chiba T, Sasabe J, Terashita K, Aiso S, Matsuoka M.
- Journal Title
  
  Neuropsychopharmacology 33(8)
  
  Pages: 2020-2032
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590240
[Journal Article] Nasal Colivelin Treatment Ameliorates Memory Impairment Related to Alzheimer's Disease2008
- Author(s)
  Yamada, M, Chiba, T, Sasabe, J, Terashita, K, Aiso, S, Matsuoka, M
- Journal Title
  
  Neuropsychopharmacology (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590240
[Journal Article] Antidepressant-like effect of Cordyceps sinensis in the mouse tail suspension test2007
- Author(s)
  Nishizawa, K, Torii, K, Kawasaki, A, Katada, M, Ito, M, Terashita, K, et. al., Matsuoka, M
- Journal Title
  
  Biol Pharm Bull 30
  
  Pages: 1758-1762
- NAID
  110006380264
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390077
[Journal Article] Antidepressant-like effect of Cordyceps sinensis in the mouse tail suspension test2007
- Author(s)
  Nishizawa, K, Torii, K, Kawasaki, A, Katada, M, Ito, M, Terashita, K, et. al., Matsuoka, M
- Journal Title
  
  Biol Pharm Bull 30
  
  Pages: 1758-1762
- NAID
  110006380264
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590240
[Journal Article] Wnt5a promotes adhesion of human dermal fibroblasts by triggering a phosphatidylinositol-3 kinase/Akt signal2007
- Author(s)
  Kawasaki, A, Torii, K, Yamashita, Y, Nishizawa, K, Kanekura, K, et. al., Matsuoka, M
- Journal Title
  
  Cell Signal 19
  
  Pages: 2498-2506
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590240
[Journal Article] CR/periphilin is a transcriptional co-repressor involved in cell cycle progression2007
- Author(s)
  Kurita, M, Suzuki, H, Kawano, Y, Aiso, S, Matsuoka, M
- Journal Title
  
  Biochem Biophys Res Commun 364
  
  Pages: 930-936
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390077
[Journal Article] Colivelin : a new-generation peptide suppressing neuronal death -Neuroprotection against neurodegenerative diseases-2007
- Author(s)
  Chiba, T, Nishimoto, I, Aiso, S, Matsuoka, M
- Journal Title
  
  Mol. Neurobiol 55
  
  Pages: 55-84
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390077
[Journal Article] Aiso S. D-Serine is a key determinant of glutamate toxicity in amyotrophic lateral sclerosis2007
- Author(s)
  Sasabe, J, Chiba, T, Yamada, M, Okamoto, K, Nishimoto, I, Matsuoka, M
- Journal Title
  
  EMBO J 26
  
  Pages: 4149-4159
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390077
[Journal Article] Wnt5a promotes adhesion of human dermal fibroblasts by triggering a phosphatidylinositol-3 kinase/ Akt signal2007
- Author(s)
  Kawasaki, A, Torii, K, Yamashita, Y, Nishizawa, K, Kanekura, K, et. al., Matsuoka, M
- Journal Title
  
  Cell Signal 19
  
  Pages: 2498-2506
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390077
[Journal Article] Colivelin prolongs survival of an ALS model mouse2006
- Author(s)
  Chiba, T., et. al., Terashita, K, Matsuoka, M, Nishimoto, I
- Journal Title
  
  Biochem Biophys Res Commun 343-3
  
  Pages: 793-798
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590240
[Journal Article] Colivelin prolongs survival of an ALS model mouse2006
- Author(s)
  Chiba T, Yamada M, Sasabe J, Terashita K, Aiso S, Matsuoka M, Nishimoto I
- Journal Title
  
  Biochemical and Biophysical Research Communications 343・3
  
  Pages: 793-798
- Data Source
  KAKENHI-PROJECT-18590240
[Journal Article] Transforming growth factor beta2 autocrinally mediates neuronal cell death induced by amyloid-b2006
- Author(s)
  Hashimoto, Y, Nawa, M, Chiba, T, Aiso, S, Nishimoto, I, Matsuoka, M
- Journal Title
  
  J Neurosci Res 83-6
  
  Pages: 1039-1047
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390077
[Journal Article] Humanin and colivelin: neuronal-death-suppressing peptides for Alzheimer's disease and amyotrophic lateral sclerosis2006
- Author(s)
  Matsuoka M., et. al.
- Journal Title
  
  CNS Drug Reviews 12・2
  
  Pages: 113-122
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390077
[Journal Article] S-nitrosothiol depletion in amyotrophic lateral sclerosis2006
- Author(s)
  Schonhoff, CM, Matsuoka, M, et. al., Gaston, B, Macdonald, T, Xu, Z, Mannick, J
- Journal Title
  
  Proc. Natl Acad Sci USA
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390077
[Journal Article] Humanin and colivelin : neuronal-death-suppressing peptides for Alzheimer's disease and amyotrophic lateral sclerosis2006
- Author(s)
  Matsuoka M. et al.
- Journal Title
  
  CNS Drug Reviews 12・2
  
  Pages: 113-122
- Data Source
  KAKENHI-PROJECT-17659117
[Journal Article] Colivelin prolongs survival of an ALS model mouse2006
- Author(s)
  Chiba, T., et. al.Matsuoka, M, Nishimoto, I
- Journal Title
  
  Biochem Biophys Res Commun 343-3
  
  Pages: 793-798
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390077
[Journal Article] Humanin and colivelin : neuronal-death-suppressing peptides for Alzheimer's disease and amyotrophic lateral sclerosis2006
- Author(s)
  Matsuoka M. et al.
- Journal Title
  
  CNS Drug Reviews 12・2
  
  Pages: 113-122
- Data Source
  KAKENHI-PROJECT-18390077
[Journal Article] Characterization of amyotrophic lateral sclerosis-linked P56S mutation of vesicle-associated membrane protein-associated protein B (VAPB /ALS8)2006
- Author(s)
  Kanekura, K., Nishimoto, I., Aiso, S., Matsuoka, M
- Journal Title
  
  J Biol Chem
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390077
[Journal Article] A Rac1/ phosphatidylinositol 3-kinase/Akt3 anti-apoptotic pathway, triggered by AlsinLF, the product of the ALS2 gene, antagonizes Cu/Zn-superoxide dismutase (SOD1) mutant-induced motoneuronal cell death.2005
- Author(s)
  Kanekura K, Hashimoto Y, Kita Y, Sasabe J, Aiso S, Nishimoto I, Matsuoka M.
- Journal Title
  
  J.Biol.Chem. 280
  
  Pages: 4532-4543
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590281
[Journal Article] The ARF tumor suppressor inhibits BCL6-mediated transcriptional repression.2005
- Author(s)
  Suzuki H, Kurita M, Mizumoto K, Moriyama M, Aiso S, Nishimoto I, Matsuoka M.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 326
  
  Pages: 242-248
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590281
[Journal Article] The ARF tumor suppressor inhibits BCL6-mediated transcriptional repression.2004
- Author(s)
  Suzuki H, Kurita M, Mizumoto K, Moriyama M, Aiso S, Nishimoto I, Matsuoka M
- Journal Title
  
  Biochem.Biophys.Res.Commun. 326
  
  Pages: 242-248
- Data Source
  KAKENHI-PROJECT-15590281
[Journal Article] Alsin, the product of ALS2 gene, suppresses SOD1 mutant neurotoxicity through RhoGEF domain by interacting with SODi mutants.2004
- Author(s)
  Kanekura K, Hashimoto Y, Niikura T, Aiso S, Matsuoka M, Nishimoto I.
- Journal Title
  
  J.Biol.Chem. 279
  
  Pages: 19247-19256
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590281
[Journal Article] The Gtx homeodomain transcription factor exerts neuroprotection using its homeodomain.2004
- Author(s)
  Hashimoto Y, Tsuji O, Kanekura K, Aiso S, Niikura T, Matsuoka M, Nishimoto I
- Journal Title
  
  J.Biol.Chem. 279
  
  Pages: 16767-16777
- Data Source
  KAKENHI-PROJECT-15590281
[Journal Article] Molecular characterization of neurohybrid cell death induced by Alzheimer's amyloid-f3 peptides via p75NTR/PLAIDD.2004
- Author(s)
  Hashimoto Y, Kaneko Y, Tsukamoto E, Frankowski H, Kouyama K, Kita Y, Niikura T, Aiso S, Bredesen DE, Matsuoka M Nishimoto I.
- Journal Title
  
  J.Neurochem. 90
  
  Pages: 549-558
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590281
[Journal Article] Overexpression of CR/periphilin downregulates Cdc7 expression and induces S-phase arrest.2004
- Author(s)
  Kurita M, Suzuki H, Masai H, Mizumoto K, Ogata E, Nishimoto I, Aiso S, Matsuoka M.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 324
  
  Pages: 554-561
- Data Source
  KAKENHI-PROJECT-15590281
[Journal Article] Characterization of V6421-AJ3PP-induced cytotoxicity in primary neurons.2004
- Author(s)
  Niikura T, Yamada M, Chiba T, Aiso S, Matsuoka M, Nishimoto I.
- Journal Title
  
  J.Neurosci.Res. 77
  
  Pages: 54-62
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590281
[Journal Article] The Gtx homeodomain transcription factor exerts neuroprotection using its homeodomain.2004
- Author(s)
  Hashimoto Y, Tsuji O, Kanekura K, Aiso S, Niikura T, Matsuoka M, Nishimoto I.
- Journal Title
  
  J.Biol.Chem. 279
  
  Pages: 16767-16777
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590281
[Journal Article] Neuroprotedive effect of activity-dependent neurotrophic factor against toxicity from familial amyotrophic lateral sclerosis-linked mutant SODi in vitro and in vivo.2004
- Author(s)
  Chiba T, Hashimoto Y, Tajima H, Yamada M, Kato R, Niikura T, Terashita K, Schulman H, Aiso S, Kita Y, Matsuoka M, Nishimoto I.
- Journal Title
  
  J.Neurosci.Res. 78
  
  Pages: 542-552
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590281
[Journal Article] Cytotoxic mechanisms by M239V presenilin 2, a little-analyzed Alzheimer's disease-causative mutant.2004
- Author(s)
  Abe Y, Hashimoto Y, Tomita Y, Terashita K, Aiso S, Tajima H, Niikura T, Matsuoka M, Nishimoto I.
- Journal Title
  
  J.Neurosci.Res. 77
  
  Pages: 583-595
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590281
[Journal Article] Targeted introduction of V6421 mutation in amyloid precursor protein gene causes functional abnormality resembling early stage of Alzheimer's disease in aged mice.2004
- Author(s)
  Kawasumi M, Chiba T, Yamada M, Miyamae-Kaneko M, Matsuoka M Nakahara I, Tomita T, Iwatsubo T, Kato S, Aiso S, Nishimoto I, Kouyama K.
- Journal Title
  
  Eur.J.Neurosci. 19
  
  Pages: 2826-2838
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590281
[Journal Article] Overexpression of CR/periphilin downregulates Cdc7 expression and induces S-phase arrest.2004
- Author(s)
  Kurita M, Suzuki H, Masai H Mizumoto K, Ogata E, Nishimoto I, Aiso S, Matsuoka M.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 324
  
  Pages: 554-561
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590281
[Journal Article] ik3-2, a relative to ik3-1/Cables, is involved in both p53-mediated and p53-independent apoptotic pathways.2003
- Author(s)
  Matsuoka M., et al.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 312
  
  Pages: 520-529
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590281
[Journal Article] Analysis of neurons created from wild-type and Alzheimer's mutation knock-in embryonic stem cells by a highly efficient differentiation protocol.2003
- Author(s)
  Abe Y, Kouyama K, Tomita T, Tomita Y, Ban N, Nawa M, Matsuoka M, Niikura T, Aiso S, Kita Y, Iwatsubo T, Nishimoto I.
- Journal Title
  
  J.Neurosci. 23
  
  Pages: 8513-8525
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590281
[Journal Article] ik3-2, a relative to ik3-1/Cables, is involved in both p53-mediated and p53-independent apoptotic pathways.2003
- Author(s)
  Matsuoka M., et al.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 301
  
  Pages: 1000-1010
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590281
[Journal Article] Multiple domains of the mouse p19ARF tumor suppressor are involved in p53-independent apoptosis.2003
- Author(s)
  Matsuoka M, Kurita M, Sudo H, Mizumoto K, Nishimoto I, Ogata E.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 301
  
  Pages: 1000-1010
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590281
[Journal Article] ik3-2, a relative to ik3-1/Cables, is involved in both p53-mediated and p53-independent apoptotic pathways.2003
- Author(s)
  Matsuoka M.Sudo H, Tsuji K, Sato H, Kurita M, Suzuki H, Nishimoto I, Ogata E.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 312
  
  Pages: 520-529
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590281
[Journal Article] p19ARF-induced p53-independent apoptosis largely occurs through BAX.2003
- Author(s)
  Suzuki H, Kurita M, Mizumoto K, Nishimoto I, Ogata E, Matsuoka M.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 312
  
  Pages: 1273-1277
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590281
[Journal Article] Immunolocalization of humanin in human sperm and testis.
- Author(s)
  Moretti E, Giannerini V, Rossini L, Matsuoka M, Trabalzini L, Collodel G
- Journal Title
  
  Fertil Steril.(Epub ahead of print)
- Data Source
  KAKENHI-PROJECT-20390072
[Journal Article] Humanin and the receptors for humanin.
- Author(s)
  Matsuoka M, Hashimoto Y
- Journal Title
  
  Mol Neurobiol. 41
  
  Pages: 22-28
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390072
[Journal Article] Identification of soluble WSX-1 not as a dominant-negative but as an alternative functional subunit of a eceptor for an anti-Alzheimer's disease rescue factor Humanin.
- Author(s)
  Hashimoto Y, Kurita M, Matsuoka M
- Journal Title
  
  Biochem Biophys Res Commun. 389
  
  Pages: 95-99
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390072
[Journal Article] Practical pharmacology training method for undergraduate medical students using a pharmacokinetic simulation model.
- Author(s)
  Hara I, Matsuoka M
- Journal Title
  
  Nippon Yakurigaku Zasshi. 136
  
  Pages: 155-159
- NAID
  10027747007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390072
[Journal Article] Colivelin--drug therapy for patients with Alzheimer's disease.
- Author(s)
  Matsuoka M
- Journal Title
  
  Nippon Yakurigaku Zasshi. 135
  
  Pages: 263-263
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390072
[Journal Article] Amyloid-beta causes memory impairment by disturbing the JAK2/STAT3 axis in hippocampal neurons.
- Author(s)
  Chiba T, Yamada M, Sasabe J, Terashita K, Shimoda M, Matsuoka M, Aiso S
- Journal Title
  
  Mol Psychiatry. 14
  
  Pages: 206-222
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390072
[Journal Article] ALS-linked P56S-VAPB mutant predisposes motor neurons to ER stress-induced death by inducing detergent-insoluble aggregation of wild-type VAPB
- Author(s)
  Suzuki H, Kanekura K, Levine T, Kohno K, Olkkonen V, Aiso S, Matsuoka M
- Journal Title
  
  J Neurochem. 108
  
  Pages: 973-998
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390072
[Journal Article] HUMANIN ; A Defender against Alzheimer's disease.
- Author(s)
  Matsuoka M
- Journal Title
  
  Recent Patents in CNS Drug Discov. 4
  
  Pages: 37-42
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390072
[Journal Article] TAG-1 is an inhibitor of TGFbeta2-induced neuronal death via amyloid beta precursor protein.
- Author(s)
  Tachi N, Hashimoto Y, Nawa M, Matsuoka M
- Journal Title
  
  Biochem Biophys Res Commun. 394
  
  Pages: 119-125
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390072
[Journal Article] ER Stress and Unfolded Protein Response in Amyotrophic Lateral Sclerosis.
- Author(s)
  Kanekura K, Suzuki H, Aiso S, Matsuoka M
- Journal Title
  
  Mol Neurobiol. 39
  
  Pages: 81-89
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390072
[Journal Article] Nasal Colivelin Treatment Ameliorates Memory Impairment Related to Alzheimer's Disease.
- Author(s)
  Yamada M, Chiba T, Sasabe J, Terashita K, Aiso S, Matsuoka M
- Journal Title
  
  Neuropsychopharmacology 33
  
  Pages: 2020-2032
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390072
[Journal Article] A novel Akt/PKB-interacting protein promotes cell adhesion and inhibits familial amyotrophic lateral sclerosis-linked mutant SOD1-induced neuronal death via inhibition of PP2A-mediated dephosphorylation of Akt/PKB.
- Author(s)
  Nawa M. Kanekura K. Hashimoto Y. Aiso S. Matsuoka M.
- Journal Title
  
  Cell Signal. 20
  
  Pages: 493-505
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390072
[Journal Article] Transforming growth factor beta2 level is elevated in nurons of Alzheimer's disease brain.
- Author(s)
  Noguchi A, Nawa M, Aiso S, Okamoto K, Matsuoka M
- Journal Title
  
  Int J.Neurosci. 120
  
  Pages: 168-175
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390072
[Journal Article] Anti-Apoptotic Action of Wnt5a in Dermal Fibroblasts Is Mediated by the PKA Signaling Pathway
- Author(s)
  Torii K, Nishizawa K, Kawasaki A, Yamashita Y, Matsuoka M
- Journal Title
  
  Cell Signal. 20
  
  Pages: 1256-1266
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390072
[Journal Article] Humanin inhibits neuronal cell death by interacting with a cytokine receptor complex or complexes involving CNTF receptor alfa/WSX-1/gp130.
- Author(s)
  Hashimoto Y, Kurita M, Aiso S, Nishimoto I, Matsuoka M
- Journal Title
  
  Mol.Biol.Cell 20
  
  Pages: 2864-2873
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390072
[Patent] カルモジュリン様皮膚蛋白質を有効成分として含む医薬生成物2011
- Inventor(s)
  松岡正明
- Industrial Property Rights Holder
  東京医科大学慶應義塾大学
- Filing Date
  2011-12-21
- Data Source
  KAKENHI-PROJECT-23390059
[Patent] カルモジュリン様皮膚蛋白質を有効成分として含む医薬生成物2011
- Inventor(s)
  松岡正明
- Industrial Property Rights Holder
  東京医科大学慶應義塾大学
- Filing Date
  2011-12-21
- Overseas
- Data Source
  KAKENHI-PROJECT-23390059
[Patent] カルモジュリン様皮膚たんぱく質を有効成分として含む医薬組成物2010
- Inventor(s)
  松岡正明
- Industrial Property Rights Holder
  東京医科大学/慶應義塾大学
- Industrial Property Number
  2010-282509
- Filing Date
  2010-12-21
- Data Source
  KAKENHI-PROJECT-20390072
[Patent] ADNF受容体2007
- Inventor(s)
  松岡正明
- Industrial Property Rights Holder
  慶應義塾
- Industrial Property Number
  2007-216664
- Filing Date
  2007-08-23
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390077
[Patent] ADNF受容体2007
- Inventor(s)
  松岡正明, 他2名
- Industrial Property Rights Holder
  慶應義塾
- Industrial Property Number
  2007-216664
- Filing Date
  2007-08-23
- Data Source
  KAKENHI-PROJECT-18390077
[Patent] 新規アルツハイマー病検出方法2006
- Inventor(s)
  松岡正明他4名
- Industrial Property Rights Holder
  松岡正明他5名
- Industrial Property Number
  2006-279113
- Filing Date
  2006-10-12
- Data Source
  KAKENHI-PROJECT-17659117
[Patent] 新規アルツハイマー病検出方法2006
- Inventor(s)
  松岡正明他4名
- Industrial Property Rights Holder
  松岡正明他5名
- Industrial Property Number
  2006-279113
- Filing Date
  2006-10-12
- Data Source
  KAKENHI-PROJECT-18390077
[Patent] 新規アルツハイマー病検出方法2006
- Inventor(s)
  松岡正明, 他4名
- Industrial Property Rights Holder
  松岡正明, 他5名
- Industrial Property Number
  2006-279113
- Filing Date
  2006-10-12
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390077
[Patent] TGFβ2を標的としたアルツハイマー病治療薬のスクリーンニング法2005
- Inventor(s)
  松岡正明, 他3名
- Industrial Property Rights Holder
  松岡正明, 他3名
- Filing Date
  2005-07-01
- Data Source
  KAKENHI-PROJECT-17659117
[Patent] 細胞増殖制御タンパク及び細胞増殖調整剤1999
- Inventor(s)
  松岡正明
- Industrial Property Rights Holder
  学校法人慶應義塾
- Patent Publication Number
  2001-157589
- Filing Date
  1999-12-02
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590281
[Presentation] An Alzheimer disease-linked mutant T835M-UNC5C causes neuronal cell death by activating an intracellular death signal cascade2016
- Author(s)
  Hashimoto Y, Toyama Y,Matsuoka M.
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜、横浜
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-15H04689
[Presentation] Dysregulation of hnRNPA1 expression induces ALS- and MSP-linked cytotoxicity2016
- Author(s)
  鈴木宏昌　松岡正明
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜、横浜
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-15H04689
[Presentation] Calmodulin-like skin protein prevents spatial learning impairment of Alzheimer's disease model mice2016
- Author(s)
  Kusakari S. Nawa M. Sudo K. Matsuoka M.
- Organizer
  Society For Neuroscience
- Place of Presentation
  San Diego
- Year and Date
  2016-11-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04689
[Presentation] An Alzheimer's disease-linked mutant T835M-UNC5C causes neuronal cell death by activating an intracellular death signal cascade.2016
- Author(s)
  橋本祐一　外山由夏　松岡正明
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜　会議センター
- Year and Date
  2016-03-11
- Data Source
  KAKENHI-PROJECT-25460343
[Presentation] An Alzheimer's disease-linked mutant T835M-UNC5C causes neuronal cell death by activating an intracellular death signal cascade2015
- Author(s)
  Yuchi Hashimoto Masaaki Matsuoka
- Organizer
  Society for Neuroscience 2015, SfN's 45th Annual Meeting
- Place of Presentation
  米国　シカゴ市
- Year and Date
  2015-10-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460343
[Presentation] An Alzheimer disease-linked mutant T835M-UNC5C causes neuronal cell death by activating an intracellular death signal cascade2015
- Author(s)
  Hashimoto Y, Matsuoka M.
- Organizer
  The 45th annual meeting of the society for neuroscience 2015
- Place of Presentation
  Chicago
- Year and Date
  2015-10-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04689
[Presentation] KCTD20, a relative of BTBD10, is a positive regulator of Akt.2014
- Author(s)
  Nawa M, Matsuoka M
- Organizer
  日本薬理学会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-23390059
[Presentation] Apollon/Bruce is upregulated by Humanin2014
- Author(s)
  橋本祐一　竹下裕二　内藤幹彦　内野博之　松岡正明
- Organizer
  第131回日本薬理学会関東部会
- Place of Presentation
  東北大学
- Year and Date
  2014-10-11
- Data Source
  KAKENHI-PROJECT-25460343
[Presentation] An anti-Alzheimer’s disease mutation makes amyloid precursor protein unable to mediate transforming growth factor β2-induced neurotoxicity2014
- Author(s)
  Hashimoto Y, Matsuoka M.
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  東北大学
- Data Source
  KAKENHI-PROJECT-25460343
[Presentation] A mutation protective against Alzheimer's disease renders amyloid β precursor protein incapable of mediating neurotoxicity.2014
- Author(s)
  Hashimoto Y, Matsuoka M.
- Organizer
  日本薬理学会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-23390059
[Presentation] SH3BP5 is essential for Humanin- mediated protection against Alzheimer' s disease-relevant toxicity.2013
- Author(s)
  Takeshita Y, Hashimoto Y, Uchino H, Matsuoka M
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2013-03-23
- Data Source
  KAKENHI-PROJECT-23659784
[Presentation] SH3BP5 is essential for Humanin-mediated protection against Alzheimer’s disease relevant toxicity2013
- Author(s)
  Takeshita Y, Hashimoto Y, Uchino H, Matsuoka M.
- Organizer
  第86回日本薬理学会
- Place of Presentation
  福岡　国際会議場
- Data Source
  KAKENHI-PROJECT-23390059
[Presentation] SH3-binding protein 5 mediates the neuroprotective effect of the secreted bioactive peptide humanin by inhibiting c-Jun NH2-terminal kinase.2013
- Author(s)
  Takeshita Y, Hashimoto Y, Nawa M, Uchino H, Matsuoka M.
- Organizer
  Society for Neuroscience
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-23390059
[Presentation] Low-grade overexpression of FUS in nucleus causes neuron cell death2013
- Author(s)
  Suzuki H, Matsuoka M.
- Organizer
  第86回日本薬理学会
- Place of Presentation
  福岡　国際会議場
- Data Source
  KAKENHI-PROJECT-23390059
[Presentation] SH3BP5 is essential for Humanin-mediated protection against Alzheimer's disease relevant toxicity2013
- Author(s)
  Takeshita Y, Hashimoto Y, Uchino H, Matsuoka M
- Organizer
  第86回日本薬理学会
- Place of Presentation
  福岡　国際会議場
- Data Source
  KAKENHI-PROJECT-23659784
[Presentation] SH3-binding protein 5 mediates the neuroprotective effect of Humanin by inhibiting c-Jun NH2-terminal kinase2013
- Author(s)
  Hashimoto Y, Takeshita Y, Nawa M, Uchino H, Matsuoka M.
- Organizer
  Society for Neuroscience 43rd annual meeting 2013
- Place of Presentation
  アメリカ合衆国カリフォルニア州サンディエゴ市
- Data Source
  KAKENHI-PROJECT-25460343
[Presentation] SH3BP5 is essential for Humanin-mediated protection against Alzheimer's disease-relevant toxicity2013
- Author(s)
  竹下裕二、橋本祐一、内野博之、松岡正明
- Organizer
  日本薬理学会第86回大会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2013-03-23
- Data Source
  KAKENHI-PROJECT-22590247
[Presentation] Amyotrophic lateral sclerosis-linked mutant VAPB enhances TDP-43-induced motor neuronal toxicity2012
- Author(s)
  Suzuki H, Matsuoka M
- Organizer
  日本薬理学会
- Place of Presentation
  京都国際会館
- Year and Date
  2012-03-16
- Data Source
  KAKENHI-PROJECT-23390059
[Presentation] Decreased expression of BTBD10 in motor neurons may contribute to the ALS pathogenesis2012
- Author(s)
  Nawa M, Matsuoka M
- Organizer
  Society for Neuroscience. 42th annual meeting 2012
- Place of Presentation
  New Orleans, USA
- Data Source
  KAKENHI-PROJECT-23390059
[Presentation] Reduced expression of BTBD10, an Akt activator, leads to motor neuron death2012
- Author(s)
  Nawa M, Kage-Nakadai E, Aiso S, Okamoto K, Mitani S, Matsuoka M
- Organizer
  日本薬理学会
- Place of Presentation
  京都国際会館
- Year and Date
  2012-03-16
- Data Source
  KAKENHI-PROJECT-23390059
[Presentation] MOCA is an integrator of the neuronal death signals that are activated by familial Alzheimer's disease-related mutants of amyloid β precursor protein and presenilins2011
- Author(s)
  Tachi N, Hashimoto Y, Matsuoka M
- Organizer
  Society for Neuroscience
- Place of Presentation
  Washington, DC
- Year and Date
  2011-11-14
- Data Source
  KAKENHI-PROJECT-23390059
[Presentation] MOCA is an integrator of the neuronal death singnals,activated by familial Alzheimer' disease-relate mutants of amyloid β precursor protein and presenilins.2011
- Author(s)
  橋本祐一、太知信之、松岡正明
- Organizer
  第84回日本薬理学会
- Place of Presentation
  横浜、日本
- Year and Date
  2011-03-22
- Data Source
  KAKENHI-PROJECT-20390072
[Presentation] Involvement of MOCA in neuronal cell death triggered by familial Alzheimer's disease-linked mutants of APP and presenilins.2011
- Author(s)
  橋本祐一、太知信之、名和幹朗、松岡正明
- Organizer
  日本薬理学会第84回大会
- Place of Presentation
  横浜
- Year and Date
  2011-03-16
- Data Source
  KAKENHI-PROJECT-22590247
[Presentation] Amyotrophic lateral sclerosis-linked mutant VAPB enhances TDP-43-induced motor neuronal toxicity2011
- Author(s)
  Suzuki H, Matsuoka M
- Organizer
  Society for Neuroscience
- Place of Presentation
  Washington, DC
- Year and Date
  2011-11-13
- Data Source
  KAKENHI-PROJECT-23390059
[Presentation] Involvement of MOCA in Alzheimer ' s disease-relevant neuronal cell death via APP and presenilins2011
- Author(s)
  Hashimoto Y, Tachi N, Matsuoka M
- Organizer
  Society for Neuroscience 2011 Annual Meeting
- Place of Presentation
  ワシントン D.C
- Year and Date
  2011-11-12
- Data Source
  KAKENHI-PROJECT-22590247
[Presentation] TDP-43-induced death is associated with altered regulation of BIM and BCL-XL and attenuated by caspase-mediated TDP-43 cleavage2010
- Author(s)
  Suzuki H., Lee K., Matsuoka M.
- Organizer
  The annual meeting of Society For Neuroscience
- Place of Presentation
  San Diego, USA
- Year and Date
  2010-11-17
- Data Source
  KAKENHI-PROJECT-20390072
[Presentation] Transforming Growth Factor β2 Level is Elevated in Neurons of Alzheimer's Disease's Brains.2010
- Author(s)
  名和幹朗、野口敦、相磯貞和、松岡正明
- Organizer
  第83回日本薬理学会
- Place of Presentation
  大阪
- Year and Date
  2010-03-17
- Data Source
  KAKENHI-PROJECT-20390072
[Presentation] Development of neurotoxicity-blocking therapy for Alzheimer's disease using Humanin.2010
- Author(s)
  Matsuoka M.
- Organizer
  The 10^<th> Biennial Meeting of the Asia-Pacific Society for Neurochemistry 2010
- Place of Presentation
  Phuket, Thailand
- Year and Date
  2010-10-18
- Data Source
  KAKENHI-PROJECT-20390072
[Presentation] TAG-1 inhibits neuronal cell death induced by interaction between TGF β2 and APP.2010
- Author(s)
  太知信之、橋本祐一、名和幹朗、松岡正明
- Organizer
  第83回日本薬理学会
- Place of Presentation
  大阪
- Year and Date
  2010-03-17
- Data Source
  KAKENHI-PROJECT-20390072
[Presentation] TDP-43-induced death is associated with altered regulation of BIM and BCL-XL and attenuated by caspase-mediated TDP-43 cleavage.2010
- Author(s)
  Suzuki H. Lee K. Matsuoka M.
- Organizer
  The annual meeting of Society For Neuroscience
- Place of Presentation
  San Diego
- Data Source
  KAKENHI-PROJECT-20390072
[Presentation] Georg Christian Terstappen, and Andrea Caricasole VSTM2L is a novel secreted antagonist of the neuroprotective peptide humanin2009
- Author(s)
  Lara Rossini, Hashimoto Y, Kurita M, Marco Gianfriddo, Carla Scali, Renza Roncarati, Davide Franceschini, Giuseppe Pollio, Lorenza Trabalzini, Matsuoka M
- Organizer
  The annual meeting of Society For Neuroscience
- Place of Presentation
  Chicago
- Data Source
  KAKENHI-PROJECT-20390072
[Presentation] A novel secreted antagonist of the neuroprotective peptide Humanin.2009
- Author(s)
  A.Caricasole, L.Rossini, Y.Hashimoto, M.Kurita, C.Scali, R.Roncarati, L.Trabalzini, M.Matsuoka, G.C.Terstappen.
- Organizer
  Society for Neuroscience 39th annual meeting 2009
- Place of Presentation
  Chicago
- Year and Date
  2009-10-20
- Data Source
  KAKENHI-PROJECT-20390072
[Presentation] The JAK2/STAT3 signaling axis mediates therapeutic effect of Colivelin on memory impairment related to Alzheimer's disease2008
- Author(s)
  Yamada, M, Chiba, T, Sasabe, J, Terashita, K, Matsuoka, M, Aiso, S
- Organizer
  The 81 th Annual Meeting of the Japanese Pharmacological Society
- Place of Presentation
  Yokohama
- Year and Date
  2008-03-17
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390077
[Presentation] The JAK2/STAT3 signaling axis mediates therapeutic effect of Colivelin on memory impairment related to Alzheimer's disease2008
- Author(s)
  Yamada, M, Chiba, T, Sasabe, J, Terashita, K, Matsuoka, M, Aiso, S
- Organizer
  The 81th Annual Meeting of the Japanese Pharmacological Society
- Place of Presentation
  Yokohama
- Year and Date
  2008-03-17
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590240
[Presentation] Nasal Colivelin treatment ameliorates Alzheimer's cognitive deficits via the JAK2/STAT3 axis2007
- Author(s)
  Matsuoka M., et. al.
- Organizer
  Keystone symposia: Molecular mechanisms of neurodegeneration
- Place of Presentation
  Taos,New Mexico
- Year and Date
  2007-01-19
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390077
[Presentation] Humanin inhibits neuronal death via a CNTF receptor alpha/ WSX-1/gp130 complex2007
- Author(s)
  Hashimoto, Y, Kurita, M, Nishimoto, I, Aiso, S, Matsuoka, M
- Organizer
  Society for Neuroscience 37th Annual Meeting 2007
- Place of Presentation
  San Diego
- Year and Date
  2007-11-06
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390077
[Presentation] Nasal Colivelin treatment ameliorates Alzheimer's cognitive deficits via the JAK2/STAT3 axis2007
- Author(s)
  Matsuoka, M, Yamada, M, Chiba, T, Sasabe, J, Sato, M, Nishimoto, I, Aiso, S
- Organizer
  Keystone symposia : Molecular mechanisms of neurodegeneration
- Place of Presentation
  Taos, New Mexico
- Year and Date
  2007-01-19
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390077
[Presentation] The JAK2/STAT3 signaling axis regulates memory in Alzheimer's disease2007
- Author(s)
  Chiba, T, Yamada, M, Sasabe, J, Terashita, K, Aiso, S, Matsuoka, M
- Organizer
  Society for Neuroscience 37th Annual Meeting 2007
- Place of Presentation
  San Diego
- Year and Date
  2007-11-06
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590240
[Presentation] Nasal Colivelin treatment ameliorates Alzheimer's cognitive deficits via the JAK2/STAT3 axis2007
- Author(s)
  Yamada, M, Chiba, T, Sasabe J, Sato, M, Nishimoto, IAiso, S, Matsuoka, M
- Organizer
  The 80th Annual Meeting of the Japanese Pharmacological Society
- Place of Presentation
  Nagoya
- Year and Date
  2007-03-16
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390077
[Presentation] The JAK2/STAT3 signaling axis regulates memory in Alzheimer's disease2007
- Author(s)
  Chiba, T, Yamada, M, Sasabe, J, Terashita, K, Aiso, S, Matsuoka, M
- Organizer
  Society for Neuroscience 37th Annual Meeting 2007
- Place of Presentation
  San Diego
- Year and Date
  2007-11-06
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390077
[Presentation] D-serine exacerbates glutamate excitotoxicity in ALS2007
- Author(s)
  Sasabe, J, Chiba, T, Yamada, M, Okamoto, K, Nishimoto, I, Aiso, S, Matsuoka, M
- Organizer
  18th International Symposia on ALS/MND (motor neuron disease)
- Place of Presentation
  Toronto, Canada
- Year and Date
  2007-12-01
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390077
[Presentation] Development of a femtomolar-acting Humanin derivative named Colive attaching ADNF to its N terminus : characterization of Colivelin-mediate neuroprotection against Alzheimer's disease-relevant insults in vitro ar vivo2007
- Author(s)
  Yamada, M, Chiba, T, Sato, M, Sasabe, J, Terashita, K, Aiso, S, Nishimoto, I, Matsuoka, M
- Organizer
  The 16th The Japanese Youg Researcher's Society of Neurobehavioral Pharmacology
- Place of Presentation
  Nagoya
- Year and Date
  2007-03-13
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390077
[Presentation] Amyotrophic lateral sclerosis-linked pro56ser vesicle-associated membrane protein-associated protein impairs unfolded protein response.2007
- Author(s)
  Kanekura, K, Suzuki, H, Nishimoto, I, Levine, T, Kohno, K, Suzuki, N, Aiso, S, Matsuoka, M
- Organizer
  18th International Symposia on ALS/MND (motor neuron disease)
- Place of Presentation
  Toronto, Canada
- Year and Date
  2007-12-01
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390077
[Presentation] Nasal Colivelin treatment for Alzheimer's disease-related memory impairment2007
- Author(s)
  Yamada, M, Chiba, T, Sasabe, J, Terashita, K, Aiso, S, Matsuoka, M
- Organizer
  Society for Neuroscience 37th Annual Meeting 2007
- Place of Presentation
  San Diego
- Year and Date
  2007-11-03
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590240
[Presentation] Identification of an alternatively spliced soluble WSX-1 as a functional anti-Alzheimer disease rescue factor Humanin2007
- Author(s)
  Hashimoto, Y, Chiba, T, Nishimoto, I, Aiso, S, Matsuoka, M
- Organizer
  The 80th Annual Meeting of the Japanese Pharmacological Society
- Place of Presentation
  Nagoya
- Year and Date
  2007-03-16
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390077
[Presentation] Nasal Colivelin treatment for Alzheimer's disease-related memory impairment2007
- Author(s)
  Yamada M, Chiba T, Sasabe J, Texashita K, Aiso S, Matsuoka M
- Organizer
  北米神経学会
- Place of Presentation
  米国サンディエゴ
- Year and Date
  2007-11-03
- Data Source
  KAKENHI-PROJECT-18590240
[Presentation] Development of a femtomolar-acting Humanin derivative named Colivelin By attaching ADNF to its N terminus : characterization of Colivelin-Mediated neuroprotection against Alzheimer's disease-relevant insults in vitro and in vivo2007
- Author(s)
  Yamada, M, Chiba, T, Sato, M, Sasabe, J, Terashita, K, Also, S, Nishimoto, I, Matsuoka, M
- Organizer
  The 16th The Japanese Youg Researcher's Society of Neurobehavioral Pharmacology
- Place of Presentation
  Nagoya
- Year and Date
  2007-03-13
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590240
[Presentation] The JAK2/STAT3 signaling axis regulates memory in Alzheimer's disease2007
- Author(s)
  Chiba T, Yamada M, Sasabe J, Terashita K, Aiso S, Matsuoka M
- Organizer
  北米神経学会
- Place of Presentation
  米国サンディエゴ
- Year and Date
  2007-11-06
- Data Source
  KAKENHI-PROJECT-18590240
[Presentation] Intranasally administered Colivelin exhibits neuroprotective effect on cholinergic neurons via the JAK/STAT axis2006
- Author(s)
  Chiba, T, Yamada, M, Sasabe, J, Sato, M, Nishimoto, I, Aiso, S, Matsuoka, M
- Organizer
  Society for Neuroscience 36th Annual Meeting 2006
- Place of Presentation
  Atlanta
- Year and Date
  2006-10-16
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390077
[Presentation] Characterization of Colivelin-mediated neuroprotection against ALS -relevant insults2006
- Author(s)
  Chiba, T, Yamada, M, Sasabe, J, Nishimoto, I, Aiso, S, Matsuoka, M
- Organizer
  International Symposia on ALS/MND (motor neuron disease)
- Place of Presentation
  Yokohama
- Year and Date
  2006-12-01
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390077
[Presentation] Elimination of apoptosis signal-regulating kinase 1 gene from ALS model mice attenuates disease progression2006
- Author(s)
  Sasabe, J, Chiba, T, Yamada, M, Nishimoto, I, Aiso, S, Matsuoka, M
- Organizer
  International Symposia on ALS/MND (motor neuron disease)
- Place of Presentation
  Yokohama
- Year and Date
  2006-12-01
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390077
[Presentation] Humanin and Colivelin, Neuroprotectors against Alzheimer's Disease2006
- Author(s)
  Masaaki, Matsuoka
- Organizer
  Joint Meeting Summer neuropeptide Conference and The European neuropeptide Club
- Place of Presentation
  Miami
- Year and Date
  2006-06-29
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390077
[Presentation] Humanin and Colivelin,Neuroprotectors against Alzheimer's Disease2006
- Author(s)
  Masaaki Matsuoka
- Organizer
  Joint Meeting Summer neuropeptide Conference and The Euronean neuropeptide Club
- Place of Presentation
  Miami
- Year and Date
  2006-06-29
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390077
[Presentation] Characterization of amyotrophic lateral sclerosis-linked P56s-vesicular membrane-associated Protein-associated protein B2006
- Author(s)
  Kanekura, K, Nishimoto, I, Aiso, S, Matsuoka, M
- Organizer
  membrane-associated Protein-associated protein B
- Place of Presentation
  Atlanta
- Year and Date
  2006-10-17
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390077
[Presentation] Nasal Colivelin treatment ameliorates Alzheimer's congnitive deficits via the JAK/STAT axis2006
- Author(s)
  Yamada, M, Chiba, T, Sasabe, J, Sato, M, Nishimoto, I, Aiso S, Matsuoka, M
- Organizer
  Neuron and disease -The 4th Neuron Satellite Meeting 2006
- Place of Presentation
  Atlanta
- Year and Date
  2006-10-13
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390077
[Presentation] Characterization of amyotrophic lateral sclerosis-linked Pro56Ser mutation of vesicle-associated membrane protein-associated protein B (VAPB/ALS8)2006
- Author(s)
  Kanekura, K, Nishimoto, I, Aiso, S, Matsuoka, M
- Organizer
  International Symposia on ALS/MND (motor neuron disease)
- Place of Presentation
  Yokohama
- Year and Date
  2006-12-02
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390077

1. NISHIMOTO Ikuo (80180652)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
2. NIIKURA Takako (10301491)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
3. MATSUDA Shuji (70296721)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
4. HASHIMOTO Yuuichi (00317330)

# of Collaborated Projects: 4 results

# of Collaborated Products: 13 results
5. CHIBA Tomohiro (60398617)

# of Collaborated Projects: 3 results

# of Collaborated Products: 26 results
6. YAMOCHI Tadanori (80306844)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
7. KOUYAMA Keisuke (30296553)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
8. Hanyu Haruo (10228520)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
9. IWAMOTO Toshihiko (10246168)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. UMAHARA Takahiko (70266477)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. TERASHITA Kenzo (00163915)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
12. 喜多淑子 (00327496)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 安川孝史 (60291936)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 田島裕久 (50306833)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 石井賢二 (10231135)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 清水聰一郎 (10385031)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 櫻井博文 (60235223)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 金高秀和 (90385021)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 鈴木宏昌

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 桑迫香奈子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 内藤幹彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 草苅伸也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Matsuoka Masaaki 松岡 正明

MATSUOKA MASAAKI 松岡 正明

MATSUOKA Masaaki 松岡 正明

Research Projects

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Analysis of secretory pathway of 14-3-3sigmaPrincipal Investigator

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A novel rescue factor for Alzheimer's diseasePrincipal Investigator

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Characterization and clinical application of endogenous Alzheimer's disease-suppressing factorPrincipal Investigator

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Humanin-mediated rescue of testicular germ cell apoptosisPrincipal Investigator

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Neuronal death-inhibiting therapy for neurodegenerative diseasePrincipal Investigator

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筋萎縮性側索硬化症発症要因としてのVAPBと小胞体ストレスの解析Principal Investigator

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Investigation on TGFbeta2 involvement in Alzheimer's disease's related neuronal death and Humanin signal transduction as an endogenous anti-Alzheimer's disease's defense factorPrincipal Investigator

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アルツハイマー病抑制因子ヒユーマニンの発癌作用の検討Principal Investigator

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Elucidation of mechanisms underlying p53-independent growth-suppressive activity for tumor suppressor proteins with p53-activating function.Principal Investigator

Matsuoka Masaaki 松岡正明

MATSUOKA MASAAKI 松岡正明

MATSUOKA Masaaki 松岡正明