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Matsuoka Masaaki  松岡 正明

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… Alternative Names

MATSUOKA MASAAKI  松岡 正明

MATSUOKA Masaaki  松岡 正明

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Researcher Number 70222297
Other IDs
External Links
Affiliation (Current) 2025: 東京医科大学, 医学部, 主任教授
Affiliation (based on the past Project Information) *help 2016 – 2017: 東京医科大学, 医学部, 主任教授
2015: 東京医科大学, 医学部, 教授
2009 – 2013: Tokyo Medical University, 医学部, 教授
2010: Keio University, 医学部, 主任教授
2007 – 2008: Keio University, School of Medicine, Associate Professor
1999 – 2006: 慶應義塾大学, 医学部, 助教授
Review Section/Research Field
Principal Investigator
General pharmacology / Pathological medical chemistry / Obstetrics and gynecology / Experimental pathology / Biological Sciences / Psychiatric science
Except Principal Investigator
Neurology / General pharmacology / Neurology / Biological Sciences / Pediatrics
Keywords
Principal Investigator
ヒューマニン / アルツハイマー病 / 神経細胞死 / TGFbeta2 / 細胞死 / ARF / BCL6 / CR / p53 / ik3-2 … More / ik3-1 / CLSP / Humanin / Cdc7 / 筋萎縮性側索硬化症 / アルツハイマー病抑制因子 / 薬理学 / 脳神経疾患 / シグナル伝達 / 神経細胞死抑制因子 / humanin / 非定型的細胞外分泌 / 14-3-3 sigma / 分泌経路 / 細胞外分泌 / 14-3-3 / Defense factor / Colivelin / Neuronal cell death / Alzheimer's disease / 防御因子 / コリベリン / BAX / 造精細胞死 / 男性不妊 / BTBD10 / ALS / 神経変性疾患 / 小胞体ストレス / 癌治療 / 細胞癌化 / cdk3 / cdk2 / 細胞周期停止 / アポトーシス / Bax / αサブユニット / ApoE4 … More
Except Principal Investigator
アルツハイマー病 / 神経細胞死 / ヒューマニン / Alzheimer's disease / Humanin / RAP / LRP / 細胞内シグナル伝達 / アミロイド前駆体タンパク質 / コリベリン / ADNF / APP / 細胞死 / 神経科学 / Apollon / UNC5C / CLSP / 創薬化学 / 脳脊髄液 / PET / タウ / アミロイド / 糖尿病 / 認知症 / Brain atrooh / Colivelin / Neuronal death / 脳萎縮 / receptor / serine isomerase / dimerization / neurodegenerative disease / βFGF / IGF-I / 生体内発現 / bFGF / IGF-1 / 分泌機構 / 構造機能相関 / HN / Apolipoprotein E3 / α2-macroglobullin / Neuronal Death / Apolipoprotein E4 / 細胞死抑制 / ApoE3 / α2マクログロブリン / ApoE4 / 細胞内シグナル伝 / 治療薬 / 受容体 / サイトカイン / 神経変性疾患 / プレセニリン / アミロイド前駆体蛋白質 / 運動神経細胞死 / ALSマウス / G93A-SOD1 / FALS / 筋萎縮性側索硬化症 / 疾患モデルマウス / ノックイン / Cre-loxP / V642I点変異 / 遺伝子ターゲティング / レチノイン酸 / モノクローナル抗体 / ヒト神経芽細胞腫株 / αシヌクレイン Less
  • Research Projects

    (21 results)
  • Research Products

    (180 results)
  • Co-Researchers

    (22 People)
  •  Pathophysiological study of diabetes-related dementia

    • Principal Investigator
      Hanyu Haruo
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      Tokyo Medical University
  •  Analysis of secretory pathway of 14-3-3sigmaPrincipal Investigator

    • Principal Investigator
      Matsuoka Masaaki
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Tokyo Medical University
  •  A novel rescue factor for Alzheimer's diseasePrincipal Investigator

    • Principal Investigator
      Matsuoka Masaaki
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General pharmacology
    • Research Institution
      Tokyo Medical University
  •  Identification of Alzheimer's disease-relevant neuronal death inhibiting molecular basis and its application for drug development

    • Principal Investigator
      HASHIMOTO YUICHI
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      Tokyo Medical University
  •  Characterization and clinical application of endogenous Alzheimer's disease-suppressing factorPrincipal Investigator

    • Principal Investigator
      MATSUOKA Masaaki
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General pharmacology
    • Research Institution
      Tokyo Medical University
  •  Humanin-mediated rescue of testicular germ cell apoptosisPrincipal Investigator

    • Principal Investigator
      MATSUOKA Masaaki
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Tokyo Medical University
  •  Search for neuronal cell death-inhibiting drugs for Alzheimer's disease-relevant signal transduction

    • Principal Investigator
      HASHIMOTO Yuuichi
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      Tokyo Medical University
  •  Neuronal death-inhibiting therapy for neurodegenerative diseasePrincipal Investigator

    • Principal Investigator
      MATSUOKA Masaaki
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General pharmacology
    • Research Institution
      Keio University
  •  筋萎縮性側索硬化症発症要因としてのVAPBと小胞体ストレスの解析Principal Investigator

    • Principal Investigator
      松岡 正明
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      General pharmacology
    • Research Institution
      Keio University
  •  Investigation on TGFbeta2 involvement in Alzheimer's disease's related neuronal death and Humanin signal transduction as an endogenous anti-Alzheimer's disease's defense factorPrincipal Investigator

    • Principal Investigator
      MATSUOKA Masaaki
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General pharmacology
    • Research Institution
      Keio University
  •  Progress from the endogenous protective factor against Alzheimer's disease

    • Principal Investigator
      TERASHITA Kenzo
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      Keio University
  •  アルツハイマー病抑制因子ヒユーマニンの発癌作用の検討Principal Investigator

    • Principal Investigator
      松岡 正明
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Experimental pathology
    • Research Institution
      Keio University
  •  FALS変異SOD1による神経変性に拮抗する新規神経再生因子の作用機序解析

    • Principal Investigator
      喜多 淑子
    • Project Period (FY)
      2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Keio University
  •  Elucidation of mechanisms underlying p53-independent growth-suppressive activity for tumor suppressor proteins with p53-activating function.Principal Investigator

    • Principal Investigator
      MATSUOKA Masaaki
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Keio University
  •  cdk2/cdk3の新しい基質ik3遺伝子群の機能解析Principal Investigator

    • Principal Investigator
      松岡 正明
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Keio University
  •  新規のAPP変異ノックインマウスを用いたアルツハイマー病発症関連遺伝子の探索

    • Principal Investigator
      KOUYAMA Keisuke
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Neurology
    • Research Institution
      Keio University
  •  Detailed characterization of Humanin, a newly identified anti-Alzheimer's disease peptide and potential starting point for development of the first curative therapy for Alzheimer's disease

    • Principal Investigator
      NISHIMOTO Ikuo
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Neurology
    • Research Institution
      KEIO UNIVERSITY
  •  神経細胞におけるアミロイド前駆体蛋白とαシヌクレインの機能の解析

    • Principal Investigator
      YAMOCHI Tadanori
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Neurology
    • Research Institution
      Keio University
  •  レチノイン酸と、神経細胞死誘導性抗APP抗体を併用した神経芽細胞腫の萌芽的治療

    • Principal Investigator
      西本 征央 (西本 育夫)
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Pediatrics
    • Research Institution
      Keio University
  •  ApoE4の誘導する神経細胞死機構の萌芽的研究Principal Investigator

    • Principal Investigator
      松岡 正明
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Psychiatric science
    • Research Institution
      Keio University
  •  Elucidation of the principal mechanism for dementia and identification of anti-dementia genes through the analysis of ApoE4 neurotoxicity

    • Principal Investigator
      NISHIMOTO Ikuo
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Neurology
    • Research Institution
      Keio University

All 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 1999 Other

All Journal Article Presentation Book Patent

  • [Book] 神経変性疾患治療の新しい可能性-ヒューマニンの役割をめぐって-2006

    • Author(s)
      松岡正明, 西本征央
    • Total Pages
      7
    • Publisher
      化学と生物
    • Data Source
      KAKENHI-PROJECT-17659117
  • [Book] 神経変性疾患治療の新しい可能性-ヒューマニンの役割をめぐって-2006

    • Author(s)
      松岡正明, 西本征央
    • Total Pages
      7
    • Publisher
      化学と生物
    • Data Source
      KAKENHI-PROJECT-18390077
  • [Book] 神経変性疾患治療の新しい可能性-ヒューマニンの役割をめぐって2006

    • Author(s)
      松岡 正明, 西本 征央
    • Publisher
      化学と生物
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18390077
  • [Journal Article] Calmodulin-like skin protein protects against spatial learning impairment in a mouse model of Alzheimer disease2018

    • Author(s)
      Shinya Kusakari, Mikiro Nawa, Katsuko Sudo, Masaaki Matsuoka
    • Journal Title

      Journal of neurochemistry

      Volume: 144 Issue: 2 Pages: 218233-218233

    • DOI

      10.1111/jnc.14258

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K08557, KAKENHI-PROJECT-15K08245, KAKENHI-PROJECT-15H04689
  • [Journal Article] Calmodulin-like skin protein is downregulated in human cerebrospinal fluids of Alzheimer's disease patients with apolipoprotein E4; a pilot study using postmortem samples.2017

    • Author(s)
      Hashimoto Y, Umahara T, Hanyu H, Iwamoto T, Matsuoka M.
    • Journal Title

      Neurol Res.

      Volume: 39 Issue: 9 Pages: 767-772

    • DOI

      10.1080/01616412.2017.1335458

    • NAID

      130007900286

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H04689
  • [Journal Article] hnRNPA1 autoregulates its own mRNA expression to remain non-cytotoxic.2017

    • Author(s)
      Suzuki H, Matsuoka M.
    • Journal Title

      Molecular and Cellular Biochemistry.

      Volume: 427 Issue: 1-2 Pages: 123-131

    • DOI

      10.1007/s11010-016-2904-x

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15H04689
  • [Journal Article] An Alzheimer's disease-linked rare mutation potentiates netrin receptor uncoordinated-5C-induced signaling that merges with amyloid β precursor protein signaling.2016

    • Author(s)
      Hashimoto Y, Toyama Y, Kusakari S, Nawa M, Matsuoka M.
    • Journal Title

      J Biol Chem.

      Volume: N/A Issue: 23 Pages: 1228212293-1228212293

    • DOI

      10.1074/jbc.m115.698092

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15H04689, KAKENHI-PROJECT-16K08557
  • [Journal Article] The Lysosomal Trafficking Transmembrane Protein 106B Is Linked to Cell Death.2016

    • Author(s)
      Suzuki H, Matsuoka M.
    • Journal Title

      J Biol Chem.

      Volume: 291 Issue: 41 Pages: 21448-21460

    • DOI

      10.1074/jbc.m116.737171

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15H04689
  • [Journal Article] Glycolytic flux controls D-serine synthesis through glyceraldehyde-3-phosphate dehydrogenase in astrocytes.2015

    • Author(s)
      Suzuki M, Sasabe J, Miyoshi Y, Kuwasako K, Muto Y, Hamase K, Matsuoka M, Imanishi N, Aiso S.
    • Journal Title

      Proc Natl Acad Sci U S A.

      Volume: 112 Issue: 17

    • DOI

      10.1073/pnas.1416117112

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K06982, KAKENHI-PROJECT-15H04689
  • [Journal Article] Protective effects of Humanin and calmodulin-like skin protein in Alzheimer's disease and broad range of abnormalities.2015

    • Author(s)
      Matsuoka M.
    • Journal Title

      Mol Neurobiol.

      Volume: 51 Issue: 3 Pages: 1232-1239

    • DOI

      10.1007/s12035-014-8799-1

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H04689
  • [Journal Article] Secreted calmodulin-like skin protein ameliorates scopolamine-induced memory impairment.2014

    • Author(s)
      Hayashi M, Tajima H, Hashimoto Y, Matsuoka M.
    • Journal Title

      NeuroReport

      Volume: not decided

    • NAID

      120005407941

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390059
  • [Journal Article] KCTD20, a relative of BTBD10, is a positive regulator of Akt.2014

    • Author(s)
      Nawa M, Matsuoka M
    • Journal Title

      BMC Biochem

      Volume: not decided Issue: 1 Pages: 1-7

    • DOI

      10.1186/1471-2091-14-27

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390059, KAKENHI-PROJECT-24790264
  • [Journal Article] A mutation protective against Alzheimer's disease renders amyloid β precursor protein incapable of mediating neurotoxicity2014

    • Author(s)
      Hashimoto Y, Matsuoka M
    • Journal Title

      J Neurochem

      Volume: not decided Issue: 2 Pages: 291-300

    • DOI

      10.1111/jnc.12717

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23390059, KAKENHI-PROJECT-25460343
  • [Journal Article] Apollon/Bruce is upregulated by Humanin.2014

    • Author(s)
      4.Hashimoto, Y., Takeshita, Y., Naito, M., Uchino, H. and Matsuoka, M
    • Journal Title

      Mol Cell Biochem.

      Volume: 397 Issue: 1-2 Pages: 147-55

    • DOI

      10.1007/s11010-014-2182-4

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25460084, KAKENHI-PROJECT-25460343
  • [Journal Article] KCTD20, a relative of BTBD10, is a positive regulator of Akt2013

    • Author(s)
      Nawa M, Matsuoka M
    • Journal Title

      BMC Biochem

      Volume: (in press)

    • Data Source
      KAKENHI-PROJECT-23390059
  • [Journal Article] Secreted calmodulin-like skin protein inhibits neuronal death in cell-based Alzheimer's disease models via the heterotrimeric Humanin receptor2013

    • Author(s)
      Hashimoto Y, Nawa M, Kurita M, Tokizawa M,Iwamatsu A, Matsuoka M
    • Journal Title

      Cell Death Dis

      Volume: 4 Issue: 3 Pages: 555-555

    • DOI

      10.1038/cddis.2013.80

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590247, KAKENHI-PROJECT-23390059, KAKENHI-PROJECT-23659784, KAKENHI-PROJECT-24790264, KAKENHI-PROJECT-25460343
  • [Journal Article] Secreted calmodulin-like skin protein ameliorates scopolamine-induced memory impairment2013

    • Author(s)
      Hayashi M, Tajima H, Hashimoto Y, Matsuoka M
    • Journal Title

      Neuroreport

    • NAID

      120005407941

    • Data Source
      KAKENHI-PROJECT-23390059
  • [Journal Article] Reduced expression of BTBD10 in anterior horn cells with Golgi fragmentation and pTDP-43-positive inclusions in patients with sporadic amyotrophic lateral sclerosis2013

    • Author(s)
      Furuta N, Makioka K, Fujita Y, Ikeda M, Takatama M, Matsuoka M, Okamoto K
    • Journal Title

      Neuropathology

      Volume: 33 Issue: 4 Pages: 397-404

    • DOI

      10.1111/neup.12010

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390059, KAKENHI-PROJECT-23591231, KAKENHI-PROJECT-24591250
  • [Journal Article] Secreted calmodulin- like skin protein ameliorates scopolamine- induced memory impairment2013

    • Author(s)
      Hayashi M, Tajima H, Hashimoto Y, Matsuoka M
    • Journal Title

      NeuroReport

      Volume: (in press)

    • NAID

      120005407941

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659784
  • [Journal Article] Secreted calmodulin-like skin protein ameliorates scopolamine-induced memory impairment.2013

    • Author(s)
      Hayashi M, Tajima H, Hashimoto Y, Matsuoka M.
    • Journal Title

      NeuroReport

      Volume: 25 Issue: 9 Pages: 751-735

    • DOI

      10.1097/wnr.0b013e328362d9fe

    • NAID

      120005407941

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25460343
  • [Journal Article] The JNK/c-Jun signaling axis contributes to the TDP-43-induced cell death.2013

    • Author(s)
      Hiroaki Suzuki and Masaaki Matsuoka
    • Journal Title

      Molecular and Cellular Biochemistry

      Volume: 372 Issue: 1-2 Pages: 241-248

    • DOI

      10.1007/s11010-012-1465-x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-12J09347, KAKENHI-PROJECT-23390059
  • [Journal Article] Secreted calmodulin-like skin protein ameliorates scopolamine-induced memory impairment2013

    • Author(s)
      Hayashi M, Tajima H, Hashimoto Y, Matsuoka M
    • Journal Title

      NeuroReport

      Volume: 24

    • NAID

      120005407941

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659784
  • [Journal Article] Secreted calmodulin-like skin protein ameliorates scopolamine-induced memory impairment2013

    • Author(s)
      Hayashi M, Tajima H, Hashimoto Y, Matsuoka M
    • Journal Title

      NeuroReport

      Volume: 24

    • NAID

      120005407941

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390059
  • [Journal Article] SH3-binding protein 5 mediates the neuroprotective effect of the secreted bioactive peptide Humanin by inhibiting c-Jun NH2-teminal kinase2013

    • Author(s)
      Takeshita Y, Hashimoto Y, Nawa M, Uchino H, Matsuoka M
    • Journal Title

      J Biol Chem

      Volume: 288 Issue: 34 Pages: 24691-24704

    • DOI

      10.1074/jbc.m113.469692

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390059, KAKENHI-PROJECT-24790264, KAKENHI-PROJECT-25460343
  • [Journal Article] The JNK/c-jun signaling axis contributes to the TDP-43-induced cell death2013

    • Author(s)
      Suzuki H, Matsuoka M
    • Journal Title

      Mol Cell Biochem

      Volume: 372 Pages: 241-248

    • Data Source
      KAKENHI-PROJECT-23390059
  • [Journal Article] TDP-43 toxicity is mediated by the unfolded protein response-unrelated induction of C/EBP homologous protein expression2012

    • Author(s)
      Suzuki H, Matsuoka M
    • Journal Title

      J Neurosci Res

      Volume: 90 Pages: 641-647

    • Data Source
      KAKENHI-PROJECT-23390059
  • [Journal Article] D-amino acid oxidase controls motoneuron degeneration through D-serine2012

    • Author(s)
      Sasabe J, Miyoshi Y, Suzuki M, Mita M, Konnno R, Matsuoka M, Hamase K, Aiso S
    • Journal Title

      Proc Natl Acad Sci USA

      Volume: 109 Pages: 627-632

    • Data Source
      KAKENHI-PROJECT-23390059
  • [Journal Article] Neuronal death-inhibiting therapy for Alzheimer's disease2012

    • Author(s)
      Matsuoka M
    • Journal Title

      Nihon Ronen Igakkai Zasshi.

      Volume: 49 Pages: 303-306

    • NAID

      40019365530

    • Data Source
      KAKENHI-PROJECT-23390059
  • [Journal Article] MOCA is an integrator of the neuronal death signals that are activated by familial Alzheimer's disease-related mutants of amyloid β precursor protein and presenilins2012

    • Author(s)
      Tachi N, Hashimoto Y, Matsuoka M
    • Journal Title

      Biochem J

      Volume: 442 Pages: 413-422

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390059
  • [Journal Article] Overexpression of TDP-43 causes partially p53-dependent G2/M arrest and p53-independent cell death in HeLa cells2012

    • Author(s)
      Lee K, Suzuki H, Aiso S, Matsuoka M
    • Journal Title

      Neurosci Lett

      Volume: 506 Pages: 271-276

    • NAID

      120005340753

    • Data Source
      KAKENHI-PROJECT-23390059
  • [Journal Article] MOCA is an integrator of the neuronal death signals that are activated by familial Alzheimer's disease-related mutants of amyloid beta precursor protein and presenilins2012

    • Author(s)
      Tachi N, Hashimoto Y, Matsuoka M
    • Journal Title

      Biochem J

      Volume: 442 Pages: 413-422

    • Data Source
      KAKENHI-PROJECT-23390059
  • [Journal Article] Reduced expression of BTBD10, an Akt activator, leads to motor neuron death2012

    • Author(s)
      Nawa M, Kage-Nakadai E, Aiso S, Okamoto K, Mitani S, Matsuoka M
    • Journal Title

      Cell Death Differ

      Volume: 19 Pages: 1398-1407

    • Data Source
      KAKENHI-PROJECT-23390059
  • [Journal Article] MOCA is an integrator of the neuronal death signals that are activated by familial Alzheimer 's disease-related mutants of amyloid beta precursor protein and presenilin2012

    • Author(s)
      Tachi N, Hashimoto Y, Matsuoka M
    • Journal Title

      Biochem. J

      Volume: 442 Issue: 2 Pages: 413-422

    • DOI

      10.1042/bj20100993

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590247
  • [Journal Article] Reduced Expression of BTBD10, an Akt activator, Drives Impairment of Motor Function2012

    • Author(s)
      Nawa M, et al
    • Journal Title

      Cell Death and Differentiation

      Volume: (in press) Issue: 8 Pages: 1398-1407

    • DOI

      10.1038/cdd.2012.19

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390063, KAKENHI-PROJECT-23390059, KAKENHI-PROJECT-23790256, KAKENHI-PROJECT-24390053, KAKENHI-PROJECT-24790264
  • [Journal Article] Amyotrophic lateral sclerosis-linked mutant VAPB enhances TDP-43-induced motor neuronal toxicity2011

    • Author(s)
      Hiroaki Suzuki
    • Journal Title

      Journal of Neurochemistry

      Volume: VOL.119 Issue: 5 Pages: 1099-1107

    • DOI

      10.1111/j.1471-4159.2011.07491.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22790261, KAKENHI-PROJECT-23390059
  • [Journal Article] Caricasole AVSTM2L is a novel secreted antagonist of the neuroprotective peptide Humanin2011

    • Author(s)
      Rossini L, Hashimoto Y, Suzuki H, Kurita M, Gianfriddo M, Scali C, Roncarati R, Franceschini D, Pollio G, Trabalzini L, Terstappen GC, Matsuoka M
    • Journal Title

      FASEB J.

      Volume: 25 Issue: 6 Pages: 1983-2000

    • DOI

      10.1096/fj.10-163535

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590247
  • [Journal Article] VSTM2L is a novel secreted antagonist of the neuroprotective peptide Humanin.2011

    • Author(s)
      Rossini L, Hashimoto Y, Suzuki H, Kurita M, Gianfriddo M, Scali C, Roncarati R, Franceschini D, Pollio G, Trabalzini L, Terstappen GC, Matsuoka M, Caricasole A.
    • Journal Title

      FASEB J.

      Volume: (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390072
  • [Journal Article] TDP-43-induced Death Is Associated with Altered Regulation of BIM and Bcl-xL and Attenuated by Caspase-mediated TDP-43 Cleavage.2011

    • Author(s)
      Suzuki H, Lee K, Matsuoka M
    • Journal Title

      J Biol Chem.

      Volume: 286 Pages: 13171-13183

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390072
  • [Journal Article] VSTM2L IS A NOVEL SECRETED ANTAGONIST OF THE NEUROPROTECTIVE PEPTIDE HUMANIN2011

    • Author(s)
      Lara Rossini, Hashimoto Y, Suzuki H, Kurita M, Marco Gianfriddo, Carla Scali, Renza Roncarati, Davide Franceschini, Giuseppe Pollio, Lorenza Trabalzin, Georg C. Terstappen, Matsuoka M, Caricasole A
    • Journal Title

      FASEB J. (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390072
  • [Journal Article] TDP-43-induced death is associated with altered regulation of BIM and Bcl-xL and attenuated by caspase-mediated TDP-43 cleavage2011

    • Author(s)
      Suzuki H, Lee K, Matsuoka M
    • Journal Title

      J Biol Chem

      Volume: 286 Pages: 13171-13183

    • Data Source
      KAKENHI-PROJECT-23390059
  • [Journal Article] Humanin signal for Alzheimer's disease2011

    • Author(s)
      Matsuoka M
    • Journal Title

      A review.J Alzheimers Dis

      Volume: 24 Suppl 2 Pages: 27-32

    • Data Source
      KAKENHI-PROJECT-23390059
  • [Journal Article] TDP-43-induced death is associated with altered regulation of BIM and Bel-xL and attenuated by caspase-mediated TDP-43 cleavage2011

    • Author(s)
      Suzuki H, Lee K, Matsuoka M
    • Journal Title

      J Biol Chem

      Volume: 286 Pages: 13171-13183

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390059
  • [Journal Article] Humanin Signal for Alzheimer's Disease.2011

    • Author(s)
      Matsuoka M
    • Journal Title

      J Alzheimers Dis.

      Volume: (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390072
  • [Journal Article] TDP-43-induced death is associated with altered regulation of BIM and BCL-XL and attenuated by caspase-mediated TDP-43 cleavage.2011

    • Author(s)
      Suzuki H, Lee K, Matsuoka M
    • Journal Title

      J Biol Chem.(Epub ahead of print)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390072
  • [Journal Article] Amyotrophic lateral sclerosis-linked mutant VAPB enhances TDP-43-induced motor neuronal toxicity2011

    • Author(s)
      Suzuki H, Matsuoka M
    • Journal Title

      J Neurochem

      Volume: 119 Pages: 1099-1107

    • Data Source
      KAKENHI-PROJECT-23390059
  • [Journal Article] Humanin signal for Alzheimer's disease2011

    • Author(s)
      Matsuoka M.
    • Journal Title

      J Alzheimers Dis

      Volume: 24Suppl 2 Pages: 27-32

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390059
  • [Journal Article] VSTM2L is a novel secreted antagonist of the neuroprotective peptide Humanin2011

    • Author(s)
      Rossini L, Hashimoto Y, Suzuki H, Kurita M, Gianfriddo M, Scali C, Roncarati R, Franceschini D, Pollio G, Trabalzini L, Terstappen GC, Matsuoka M, Caricasole A
    • Journal Title

      FASEB J

      Volume: 25 Pages: 1983-2000

    • Data Source
      KAKENHI-PROJECT-23390059
  • [Journal Article] Humanin Signal for Alzheimer's Disease2011

    • Author(s)
      Matsuoka M
    • Journal Title

      J Alzheimers Dis.(Epub ahead of print)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390072
  • [Journal Article] Humanin and the receptors for Humanin.2010

    • Author(s)
      Matsuoka M, Hashimoto Y
    • Journal Title

      Molecular Neurobiology 41

      Pages: 22-28

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390072
  • [Journal Article] Transforming Growth Factor β2 Level is Elevated in Neurons of Alzheimer's Disease's Brains.2010

    • Author(s)
      Noguchi M, Nawa M, Okamoto K, Aiso S, Matsuoka M.
    • Journal Title

      International Journal of Neuroscience 120

      Pages: 168-175

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390072
  • [Journal Article] Immunolocalization of humanin in human sperm and testis.2010

    • Author(s)
      Moretti E, Giannerini V, Rossini L, Matsuoka M, Trabalzini L, Collodel G.
    • Journal Title

      Fertil Steril.

      Volume: 94 Pages: 2888-2890

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390072
  • [Journal Article] TAG-1 is an inhibitor of TGF β 2-induced neuronal death via amyloid β precursor protein2010

    • Author(s)
      Tachi N, Hashimoto Y, Nawa M, Matsuoka M.
    • Journal Title

      Biochemical and Biophysical Research Communications 394

      Pages: 119-125

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390072
  • [Journal Article] Humanin and the receptors for Humanin2010

    • Author(s)
      Matsuoka, M., Hashimoto, Y.
    • Journal Title

      Molecular Neurobiology

      Volume: 41 Pages: 22-28

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590247
  • [Journal Article] Transforming growth factor beta2 level is elevated in nurons of Alzheimer's disease brain.2010

    • Author(s)
      Noguchi A, Nawa M, Aiso S, Okamoto K, Matsuoka M
    • Journal Title

      Int J.Neurosci.

      Volume: 120 Pages: 168-175

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390072
  • [Journal Article] Identification of soluble WSX-1 not as a dominant-negative but as an alternative functional subunit of a receptor for an anti-Alzheimer's diseaserescue factor Humanin.2009

    • Author(s)
      Hashimoto Y, Kurita M, Matsuoka M.
    • Journal Title

      Biochemical and Biophysical Research Communications 389

      Pages: 95-99

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390072
  • [Journal Article] Humanin inhibits neuronal cell death by interacting with a cytokine receptor complex or complexes involving CNTF receptor alfa/WSX-1/gp130.2009

    • Author(s)
      Hashimoto Y, Kurita M, Aiso S, Nishimoto I, Matsuoka M.
    • Journal Title

      Molecular Biology of the Cell 20

      Pages: 2864-2873

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390072
  • [Journal Article] Humanin ; a defender against Alzheimer's disease?2009

    • Author(s)
      Matsuoka M.
    • Journal Title

      Recent Patents in CNS Drug Discov 4

      Pages: 37-42

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659063
  • [Journal Article] Humanin ; a defender against Alzheimer's disease?2009

    • Author(s)
      Matsuoka M.
    • Journal Title

      Recent Patents in CNS Drug Discov 4

      Pages: 37-42

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390072
  • [Journal Article] A novel Akt/PKB-interacting protein promotes cell adhesion and inhibits familial amyotrophic lateral sclerosis-linked mutant SOD1-induced neuronal death via inhibition of PP2A-mediated dephosphorylation of Akt/PKB2008

    • Author(s)
      Nawa, M, Kanekura, K, Hashimoto, Y, Aiso, S, Matsuoka, M
    • Journal Title

      Cell Signal 20

      Pages: 493-505

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390077
  • [Journal Article] Anti-Apoptotic Action of Wnt5a in Dermal Fibroblasts Is Mediated by the PKA Signaling Pathway2008

    • Author(s)
      Torii, K, Nishizawa, K, Kawasaki, A, Yamashita, Y, et. al., Matsuoka, M
    • Journal Title

      Cell Signal 20

      Pages: 1256-1266

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390077
  • [Journal Article] Anti-Apoptotic Action of Wnt5a in Dermal Fibroblasts Is Mediated by the PKA Signaling Pathway2008

    • Author(s)
      Torii, K, Nishizawa, K, Kawasaki, A, Yamashita, Y, et. al., Matsuoka, M
    • Journal Title

      Cell Signal 20

      Pages: 1256-1266

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590240
  • [Journal Article] Nasal ColivelinTreatment Ameliorates Memory Impairment Related to Alzheimer'sDisease.2008

    • Author(s)
      Yamada, M, Chiba, T, Sasabe, J, Terashita, K, Aiso, S, Matsuoka, M
    • Journal Title

      Neuropsychopharmacology (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390077
  • [Journal Article] Nasal Cohvelin Tleatment Ameliorates Memory Impairment Related to Alzheimer's Disease2008

    • Author(s)
      Yamada M, Chiba T, Sasabe J, Terashita K, Aiso S, Matsuoka M.
    • Journal Title

      Neuropsychopharmacology 33(8)

      Pages: 2020-2032

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590240
  • [Journal Article] Nasal Colivelin Treatment Ameliorates Memory Impairment Related to Alzheimer's Disease2008

    • Author(s)
      Yamada, M, Chiba, T, Sasabe, J, Terashita, K, Aiso, S, Matsuoka, M
    • Journal Title

      Neuropsychopharmacology (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590240
  • [Journal Article] Antidepressant-like effect of Cordyceps sinensis in the mouse tail suspension test2007

    • Author(s)
      Nishizawa, K, Torii, K, Kawasaki, A, Katada, M, Ito, M, Terashita, K, et. al., Matsuoka, M
    • Journal Title

      Biol Pharm Bull 30

      Pages: 1758-1762

    • NAID

      110006380264

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390077
  • [Journal Article] Antidepressant-like effect of Cordyceps sinensis in the mouse tail suspension test2007

    • Author(s)
      Nishizawa, K, Torii, K, Kawasaki, A, Katada, M, Ito, M, Terashita, K, et. al., Matsuoka, M
    • Journal Title

      Biol Pharm Bull 30

      Pages: 1758-1762

    • NAID

      110006380264

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590240
  • [Journal Article] Wnt5a promotes adhesion of human dermal fibroblasts by triggering a phosphatidylinositol-3 kinase/Akt signal2007

    • Author(s)
      Kawasaki, A, Torii, K, Yamashita, Y, Nishizawa, K, Kanekura, K, et. al., Matsuoka, M
    • Journal Title

      Cell Signal 19

      Pages: 2498-2506

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590240
  • [Journal Article] CR/periphilin is a transcriptional co-repressor involved in cell cycle progression2007

    • Author(s)
      Kurita, M, Suzuki, H, Kawano, Y, Aiso, S, Matsuoka, M
    • Journal Title

      Biochem Biophys Res Commun 364

      Pages: 930-936

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390077
  • [Journal Article] Colivelin : a new-generation peptide suppressing neuronal death -Neuroprotection against neurodegenerative diseases-2007

    • Author(s)
      Chiba, T, Nishimoto, I, Aiso, S, Matsuoka, M
    • Journal Title

      Mol. Neurobiol 55

      Pages: 55-84

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390077
  • [Journal Article] Aiso S. D-Serine is a key determinant of glutamate toxicity in amyotrophic lateral sclerosis2007

    • Author(s)
      Sasabe, J, Chiba, T, Yamada, M, Okamoto, K, Nishimoto, I, Matsuoka, M
    • Journal Title

      EMBO J 26

      Pages: 4149-4159

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390077
  • [Journal Article] Wnt5a promotes adhesion of human dermal fibroblasts by triggering a phosphatidylinositol-3 kinase/ Akt signal2007

    • Author(s)
      Kawasaki, A, Torii, K, Yamashita, Y, Nishizawa, K, Kanekura, K, et. al., Matsuoka, M
    • Journal Title

      Cell Signal 19

      Pages: 2498-2506

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390077
  • [Journal Article] Colivelin prolongs survival of an ALS model mouse2006

    • Author(s)
      Chiba, T., et. al., Terashita, K, Matsuoka, M, Nishimoto, I
    • Journal Title

      Biochem Biophys Res Commun 343-3

      Pages: 793-798

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590240
  • [Journal Article] Colivelin prolongs survival of an ALS model mouse2006

    • Author(s)
      Chiba T, Yamada M, Sasabe J, Terashita K, Aiso S, Matsuoka M, Nishimoto I
    • Journal Title

      Biochemical and Biophysical Research Communications 343・3

      Pages: 793-798

    • Data Source
      KAKENHI-PROJECT-18590240
  • [Journal Article] Transforming growth factor beta2 autocrinally mediates neuronal cell death induced by amyloid-b2006

    • Author(s)
      Hashimoto, Y, Nawa, M, Chiba, T, Aiso, S, Nishimoto, I, Matsuoka, M
    • Journal Title

      J Neurosci Res 83-6

      Pages: 1039-1047

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390077
  • [Journal Article] Humanin and colivelin: neuronal-death-suppressing peptides for Alzheimer's disease and amyotrophic lateral sclerosis2006

    • Author(s)
      Matsuoka M., et. al.
    • Journal Title

      CNS Drug Reviews 12・2

      Pages: 113-122

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390077
  • [Journal Article] S-nitrosothiol depletion in amyotrophic lateral sclerosis2006

    • Author(s)
      Schonhoff, CM, Matsuoka, M, et. al., Gaston, B, Macdonald, T, Xu, Z, Mannick, J
    • Journal Title

      Proc. Natl Acad Sci USA

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390077
  • [Journal Article] Humanin and colivelin : neuronal-death-suppressing peptides for Alzheimer's disease and amyotrophic lateral sclerosis2006

    • Author(s)
      Matsuoka M. et al.
    • Journal Title

      CNS Drug Reviews 12・2

      Pages: 113-122

    • Data Source
      KAKENHI-PROJECT-17659117
  • [Journal Article] Colivelin prolongs survival of an ALS model mouse2006

    • Author(s)
      Chiba, T., et. al.Matsuoka, M, Nishimoto, I
    • Journal Title

      Biochem Biophys Res Commun 343-3

      Pages: 793-798

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390077
  • [Journal Article] Humanin and colivelin : neuronal-death-suppressing peptides for Alzheimer's disease and amyotrophic lateral sclerosis2006

    • Author(s)
      Matsuoka M. et al.
    • Journal Title

      CNS Drug Reviews 12・2

      Pages: 113-122

    • Data Source
      KAKENHI-PROJECT-18390077
  • [Journal Article] Characterization of amyotrophic lateral sclerosis-linked P56S mutation of vesicle-associated membrane protein-associated protein B (VAPB /ALS8)2006

    • Author(s)
      Kanekura, K., Nishimoto, I., Aiso, S., Matsuoka, M
    • Journal Title

      J Biol Chem

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390077
  • [Journal Article] A Rac1/ phosphatidylinositol 3-kinase/Akt3 anti-apoptotic pathway, triggered by AlsinLF, the product of the ALS2 gene, antagonizes Cu/Zn-superoxide dismutase (SOD1) mutant-induced motoneuronal cell death.2005

    • Author(s)
      Kanekura K, Hashimoto Y, Kita Y, Sasabe J, Aiso S, Nishimoto I, Matsuoka M.
    • Journal Title

      J.Biol.Chem. 280

      Pages: 4532-4543

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590281
  • [Journal Article] The ARF tumor suppressor inhibits BCL6-mediated transcriptional repression.2005

    • Author(s)
      Suzuki H, Kurita M, Mizumoto K, Moriyama M, Aiso S, Nishimoto I, Matsuoka M.
    • Journal Title

      Biochem.Biophys.Res.Commun. 326

      Pages: 242-248

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590281
  • [Journal Article] The ARF tumor suppressor inhibits BCL6-mediated transcriptional repression.2004

    • Author(s)
      Suzuki H, Kurita M, Mizumoto K, Moriyama M, Aiso S, Nishimoto I, Matsuoka M
    • Journal Title

      Biochem.Biophys.Res.Commun. 326

      Pages: 242-248

    • Data Source
      KAKENHI-PROJECT-15590281
  • [Journal Article] Alsin, the product of ALS2 gene, suppresses SOD1 mutant neurotoxicity through RhoGEF domain by interacting with SODi mutants.2004

    • Author(s)
      Kanekura K, Hashimoto Y, Niikura T, Aiso S, Matsuoka M, Nishimoto I.
    • Journal Title

      J.Biol.Chem. 279

      Pages: 19247-19256

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590281
  • [Journal Article] The Gtx homeodomain transcription factor exerts neuroprotection using its homeodomain.2004

    • Author(s)
      Hashimoto Y, Tsuji O, Kanekura K, Aiso S, Niikura T, Matsuoka M, Nishimoto I
    • Journal Title

      J.Biol.Chem. 279

      Pages: 16767-16777

    • Data Source
      KAKENHI-PROJECT-15590281
  • [Journal Article] Molecular characterization of neurohybrid cell death induced by Alzheimer's amyloid-f3 peptides via p75NTR/PLAIDD.2004

    • Author(s)
      Hashimoto Y, Kaneko Y, Tsukamoto E, Frankowski H, Kouyama K, Kita Y, Niikura T, Aiso S, Bredesen DE, Matsuoka M Nishimoto I.
    • Journal Title

      J.Neurochem. 90

      Pages: 549-558

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590281
  • [Journal Article] Overexpression of CR/periphilin downregulates Cdc7 expression and induces S-phase arrest.2004

    • Author(s)
      Kurita M, Suzuki H, Masai H, Mizumoto K, Ogata E, Nishimoto I, Aiso S, Matsuoka M.
    • Journal Title

      Biochem.Biophys.Res.Commun. 324

      Pages: 554-561

    • Data Source
      KAKENHI-PROJECT-15590281
  • [Journal Article] Characterization of V6421-AJ3PP-induced cytotoxicity in primary neurons.2004

    • Author(s)
      Niikura T, Yamada M, Chiba T, Aiso S, Matsuoka M, Nishimoto I.
    • Journal Title

      J.Neurosci.Res. 77

      Pages: 54-62

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590281
  • [Journal Article] The Gtx homeodomain transcription factor exerts neuroprotection using its homeodomain.2004

    • Author(s)
      Hashimoto Y, Tsuji O, Kanekura K, Aiso S, Niikura T, Matsuoka M, Nishimoto I.
    • Journal Title

      J.Biol.Chem. 279

      Pages: 16767-16777

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590281
  • [Journal Article] Neuroprotedive effect of activity-dependent neurotrophic factor against toxicity from familial amyotrophic lateral sclerosis-linked mutant SODi in vitro and in vivo.2004

    • Author(s)
      Chiba T, Hashimoto Y, Tajima H, Yamada M, Kato R, Niikura T, Terashita K, Schulman H, Aiso S, Kita Y, Matsuoka M, Nishimoto I.
    • Journal Title

      J.Neurosci.Res. 78

      Pages: 542-552

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590281
  • [Journal Article] Cytotoxic mechanisms by M239V presenilin 2, a little-analyzed Alzheimer's disease-causative mutant.2004

    • Author(s)
      Abe Y, Hashimoto Y, Tomita Y, Terashita K, Aiso S, Tajima H, Niikura T, Matsuoka M, Nishimoto I.
    • Journal Title

      J.Neurosci.Res. 77

      Pages: 583-595

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590281
  • [Journal Article] Targeted introduction of V6421 mutation in amyloid precursor protein gene causes functional abnormality resembling early stage of Alzheimer's disease in aged mice.2004

    • Author(s)
      Kawasumi M, Chiba T, Yamada M, Miyamae-Kaneko M, Matsuoka M Nakahara I, Tomita T, Iwatsubo T, Kato S, Aiso S, Nishimoto I, Kouyama K.
    • Journal Title

      Eur.J.Neurosci. 19

      Pages: 2826-2838

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590281
  • [Journal Article] Overexpression of CR/periphilin downregulates Cdc7 expression and induces S-phase arrest.2004

    • Author(s)
      Kurita M, Suzuki H, Masai H Mizumoto K, Ogata E, Nishimoto I, Aiso S, Matsuoka M.
    • Journal Title

      Biochem.Biophys.Res.Commun. 324

      Pages: 554-561

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590281
  • [Journal Article] ik3-2, a relative to ik3-1/Cables, is involved in both p53-mediated and p53-independent apoptotic pathways.2003

    • Author(s)
      Matsuoka M., et al.
    • Journal Title

      Biochem.Biophys.Res.Commun. 312

      Pages: 520-529

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590281
  • [Journal Article] Analysis of neurons created from wild-type and Alzheimer's mutation knock-in embryonic stem cells by a highly efficient differentiation protocol.2003

    • Author(s)
      Abe Y, Kouyama K, Tomita T, Tomita Y, Ban N, Nawa M, Matsuoka M, Niikura T, Aiso S, Kita Y, Iwatsubo T, Nishimoto I.
    • Journal Title

      J.Neurosci. 23

      Pages: 8513-8525

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590281
  • [Journal Article] ik3-2, a relative to ik3-1/Cables, is involved in both p53-mediated and p53-independent apoptotic pathways.2003

    • Author(s)
      Matsuoka M., et al.
    • Journal Title

      Biochem.Biophys.Res.Commun. 301

      Pages: 1000-1010

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590281
  • [Journal Article] Multiple domains of the mouse p19ARF tumor suppressor are involved in p53-independent apoptosis.2003

    • Author(s)
      Matsuoka M, Kurita M, Sudo H, Mizumoto K, Nishimoto I, Ogata E.
    • Journal Title

      Biochem.Biophys.Res.Commun. 301

      Pages: 1000-1010

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590281
  • [Journal Article] ik3-2, a relative to ik3-1/Cables, is involved in both p53-mediated and p53-independent apoptotic pathways.2003

    • Author(s)
      Matsuoka M.Sudo H, Tsuji K, Sato H, Kurita M, Suzuki H, Nishimoto I, Ogata E.
    • Journal Title

      Biochem.Biophys.Res.Commun. 312

      Pages: 520-529

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590281
  • [Journal Article] p19ARF-induced p53-independent apoptosis largely occurs through BAX.2003

    • Author(s)
      Suzuki H, Kurita M, Mizumoto K, Nishimoto I, Ogata E, Matsuoka M.
    • Journal Title

      Biochem.Biophys.Res.Commun. 312

      Pages: 1273-1277

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590281
  • [Journal Article] Immunolocalization of humanin in human sperm and testis.

    • Author(s)
      Moretti E, Giannerini V, Rossini L, Matsuoka M, Trabalzini L, Collodel G
    • Journal Title

      Fertil Steril.(Epub ahead of print)

    • Data Source
      KAKENHI-PROJECT-20390072
  • [Journal Article] Humanin and the receptors for humanin.

    • Author(s)
      Matsuoka M, Hashimoto Y
    • Journal Title

      Mol Neurobiol. 41

      Pages: 22-28

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390072
  • [Journal Article] Identification of soluble WSX-1 not as a dominant-negative but as an alternative functional subunit of a eceptor for an anti-Alzheimer's disease rescue factor Humanin.

    • Author(s)
      Hashimoto Y, Kurita M, Matsuoka M
    • Journal Title

      Biochem Biophys Res Commun. 389

      Pages: 95-99

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390072
  • [Journal Article] Practical pharmacology training method for undergraduate medical students using a pharmacokinetic simulation model.

    • Author(s)
      Hara I, Matsuoka M
    • Journal Title

      Nippon Yakurigaku Zasshi. 136

      Pages: 155-159

    • NAID

      10027747007

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390072
  • [Journal Article] Colivelin--drug therapy for patients with Alzheimer's disease.

    • Author(s)
      Matsuoka M
    • Journal Title

      Nippon Yakurigaku Zasshi. 135

      Pages: 263-263

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390072
  • [Journal Article] Amyloid-beta causes memory impairment by disturbing the JAK2/STAT3 axis in hippocampal neurons.

    • Author(s)
      Chiba T, Yamada M, Sasabe J, Terashita K, Shimoda M, Matsuoka M, Aiso S
    • Journal Title

      Mol Psychiatry. 14

      Pages: 206-222

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390072
  • [Journal Article] ALS-linked P56S-VAPB mutant predisposes motor neurons to ER stress-induced death by inducing detergent-insoluble aggregation of wild-type VAPB

    • Author(s)
      Suzuki H, Kanekura K, Levine T, Kohno K, Olkkonen V, Aiso S, Matsuoka M
    • Journal Title

      J Neurochem. 108

      Pages: 973-998

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390072
  • [Journal Article] HUMANIN ; A Defender against Alzheimer's disease.

    • Author(s)
      Matsuoka M
    • Journal Title

      Recent Patents in CNS Drug Discov. 4

      Pages: 37-42

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390072
  • [Journal Article] TAG-1 is an inhibitor of TGFbeta2-induced neuronal death via amyloid beta precursor protein.

    • Author(s)
      Tachi N, Hashimoto Y, Nawa M, Matsuoka M
    • Journal Title

      Biochem Biophys Res Commun. 394

      Pages: 119-125

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390072
  • [Journal Article] ER Stress and Unfolded Protein Response in Amyotrophic Lateral Sclerosis.

    • Author(s)
      Kanekura K, Suzuki H, Aiso S, Matsuoka M
    • Journal Title

      Mol Neurobiol. 39

      Pages: 81-89

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390072
  • [Journal Article] Nasal Colivelin Treatment Ameliorates Memory Impairment Related to Alzheimer's Disease.

    • Author(s)
      Yamada M, Chiba T, Sasabe J, Terashita K, Aiso S, Matsuoka M
    • Journal Title

      Neuropsychopharmacology 33

      Pages: 2020-2032

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390072
  • [Journal Article] A novel Akt/PKB-interacting protein promotes cell adhesion and inhibits familial amyotrophic lateral sclerosis-linked mutant SOD1-induced neuronal death via inhibition of PP2A-mediated dephosphorylation of Akt/PKB.

    • Author(s)
      Nawa M. Kanekura K. Hashimoto Y. Aiso S. Matsuoka M.
    • Journal Title

      Cell Signal. 20

      Pages: 493-505

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390072
  • [Journal Article] Transforming growth factor beta2 level is elevated in nurons of Alzheimer's disease brain.

    • Author(s)
      Noguchi A, Nawa M, Aiso S, Okamoto K, Matsuoka M
    • Journal Title

      Int J.Neurosci. 120

      Pages: 168-175

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390072
  • [Journal Article] Anti-Apoptotic Action of Wnt5a in Dermal Fibroblasts Is Mediated by the PKA Signaling Pathway

    • Author(s)
      Torii K, Nishizawa K, Kawasaki A, Yamashita Y, Matsuoka M
    • Journal Title

      Cell Signal. 20

      Pages: 1256-1266

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390072
  • [Journal Article] Humanin inhibits neuronal cell death by interacting with a cytokine receptor complex or complexes involving CNTF receptor alfa/WSX-1/gp130.

    • Author(s)
      Hashimoto Y, Kurita M, Aiso S, Nishimoto I, Matsuoka M
    • Journal Title

      Mol.Biol.Cell 20

      Pages: 2864-2873

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390072
  • [Patent] カルモジュリン様皮膚蛋白質を有効成分として含む医薬生成物2011

    • Inventor(s)
      松岡正明
    • Industrial Property Rights Holder
      東京医科大学慶應義塾大学
    • Filing Date
      2011-12-21
    • Data Source
      KAKENHI-PROJECT-23390059
  • [Patent] カルモジュリン様皮膚蛋白質を有効成分として含む医薬生成物2011

    • Inventor(s)
      松岡正明
    • Industrial Property Rights Holder
      東京医科大学慶應義塾大学
    • Filing Date
      2011-12-21
    • Overseas
    • Data Source
      KAKENHI-PROJECT-23390059
  • [Patent] カルモジュリン様皮膚たんぱく質を有効成分として含む医薬組成物2010

    • Inventor(s)
      松岡正明
    • Industrial Property Rights Holder
      東京医科大学/慶應義塾大学
    • Industrial Property Number
      2010-282509
    • Filing Date
      2010-12-21
    • Data Source
      KAKENHI-PROJECT-20390072
  • [Patent] ADNF受容体2007

    • Inventor(s)
      松岡 正明
    • Industrial Property Rights Holder
      慶應義塾
    • Industrial Property Number
      2007-216664
    • Filing Date
      2007-08-23
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18390077
  • [Patent] ADNF受容体2007

    • Inventor(s)
      松岡 正明, 他2名
    • Industrial Property Rights Holder
      慶應義塾
    • Industrial Property Number
      2007-216664
    • Filing Date
      2007-08-23
    • Data Source
      KAKENHI-PROJECT-18390077
  • [Patent] 新規アルツハイマー病検出方法2006

    • Inventor(s)
      松岡正明他4名
    • Industrial Property Rights Holder
      松岡正明他5名
    • Industrial Property Number
      2006-279113
    • Filing Date
      2006-10-12
    • Data Source
      KAKENHI-PROJECT-17659117
  • [Patent] 新規アルツハイマー病検出方法2006

    • Inventor(s)
      松岡正明 他4名
    • Industrial Property Rights Holder
      松岡正明 他5名
    • Industrial Property Number
      2006-279113
    • Filing Date
      2006-10-12
    • Data Source
      KAKENHI-PROJECT-18390077
  • [Patent] 新規アルツハイマー病検出方法2006

    • Inventor(s)
      松岡 正明, 他4名
    • Industrial Property Rights Holder
      松岡 正明, 他5名
    • Industrial Property Number
      2006-279113
    • Filing Date
      2006-10-12
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18390077
  • [Patent] TGFβ2を標的としたアルツハイマー病治療薬のスクリーンニング法2005

    • Inventor(s)
      松岡正明, 他3名
    • Industrial Property Rights Holder
      松岡正明, 他3名
    • Filing Date
      2005-07-01
    • Data Source
      KAKENHI-PROJECT-17659117
  • [Patent] 細胞増殖制御タンパク及び細胞増殖調整剤1999

    • Inventor(s)
      松岡 正明
    • Industrial Property Rights Holder
      学校法人慶應義塾
    • Patent Publication Number
      2001-157589
    • Filing Date
      1999-12-02
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590281
  • [Presentation] An Alzheimer disease-linked mutant T835M-UNC5C causes neuronal cell death by activating an intracellular death signal cascade2016

    • Author(s)
      Hashimoto Y, Toyama Y,Matsuoka M.
    • Organizer
      第89回日本薬理学会年会
    • Place of Presentation
      パシフィコ横浜、横浜
    • Year and Date
      2016-03-09
    • Data Source
      KAKENHI-PROJECT-15H04689
  • [Presentation] Dysregulation of hnRNPA1 expression induces ALS- and MSP-linked cytotoxicity2016

    • Author(s)
      鈴木宏昌 松岡正明
    • Organizer
      第89回日本薬理学会年会
    • Place of Presentation
      パシフィコ横浜、横浜
    • Year and Date
      2016-03-09
    • Data Source
      KAKENHI-PROJECT-15H04689
  • [Presentation] Calmodulin-like skin protein prevents spatial learning impairment of Alzheimer's disease model mice2016

    • Author(s)
      Kusakari S. Nawa M. Sudo K. Matsuoka M.
    • Organizer
      Society For Neuroscience
    • Place of Presentation
      San Diego
    • Year and Date
      2016-11-12
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04689
  • [Presentation] An Alzheimer's disease-linked mutant T835M-UNC5C causes neuronal cell death by activating an intracellular death signal cascade.2016

    • Author(s)
      橋本祐一 外山由夏 松岡正明
    • Organizer
      第89回日本薬理学会年会
    • Place of Presentation
      パシフィコ横浜 会議センター
    • Year and Date
      2016-03-11
    • Data Source
      KAKENHI-PROJECT-25460343
  • [Presentation] An Alzheimer's disease-linked mutant T835M-UNC5C causes neuronal cell death by activating an intracellular death signal cascade2015

    • Author(s)
      Yuchi Hashimoto Masaaki Matsuoka
    • Organizer
      Society for Neuroscience 2015, SfN's 45th Annual Meeting
    • Place of Presentation
      米国 シカゴ市
    • Year and Date
      2015-10-17
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25460343
  • [Presentation] An Alzheimer disease-linked mutant T835M-UNC5C causes neuronal cell death by activating an intracellular death signal cascade2015

    • Author(s)
      Hashimoto Y, Matsuoka M.
    • Organizer
      The 45th annual meeting of the society for neuroscience 2015
    • Place of Presentation
      Chicago
    • Year and Date
      2015-10-17
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04689
  • [Presentation] KCTD20, a relative of BTBD10, is a positive regulator of Akt.2014

    • Author(s)
      Nawa M, Matsuoka M
    • Organizer
      日本薬理学会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-23390059
  • [Presentation] Apollon/Bruce is upregulated by Humanin2014

    • Author(s)
      橋本祐一 竹下裕二 内藤幹彦 内野博之 松岡正明
    • Organizer
      第131回日本薬理学会関東部会
    • Place of Presentation
      東北大学
    • Year and Date
      2014-10-11
    • Data Source
      KAKENHI-PROJECT-25460343
  • [Presentation] An anti-Alzheimer’s disease mutation makes amyloid precursor protein unable to mediate transforming growth factor β2-induced neurotoxicity2014

    • Author(s)
      Hashimoto Y, Matsuoka M.
    • Organizer
      第87回日本薬理学会年会
    • Place of Presentation
      東北大学
    • Data Source
      KAKENHI-PROJECT-25460343
  • [Presentation] A mutation protective against Alzheimer's disease renders amyloid β precursor protein incapable of mediating neurotoxicity.2014

    • Author(s)
      Hashimoto Y, Matsuoka M.
    • Organizer
      日本薬理学会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-23390059
  • [Presentation] SH3BP5 is essential for Humanin- mediated protection against Alzheimer' s disease-relevant toxicity.2013

    • Author(s)
      Takeshita Y, Hashimoto Y, Uchino H, Matsuoka M
    • Organizer
      第86回日本薬理学会年会
    • Place of Presentation
      福岡国際会議場
    • Year and Date
      2013-03-23
    • Data Source
      KAKENHI-PROJECT-23659784
  • [Presentation] SH3BP5 is essential for Humanin-mediated protection against Alzheimer’s disease relevant toxicity2013

    • Author(s)
      Takeshita Y, Hashimoto Y, Uchino H, Matsuoka M.
    • Organizer
      第86回日本薬理学会
    • Place of Presentation
      福岡 国際会議場
    • Data Source
      KAKENHI-PROJECT-23390059
  • [Presentation] SH3-binding protein 5 mediates the neuroprotective effect of the secreted bioactive peptide humanin by inhibiting c-Jun NH2-terminal kinase.2013

    • Author(s)
      Takeshita Y, Hashimoto Y, Nawa M, Uchino H, Matsuoka M.
    • Organizer
      Society for Neuroscience
    • Place of Presentation
      San Diego, USA
    • Data Source
      KAKENHI-PROJECT-23390059
  • [Presentation] Low-grade overexpression of FUS in nucleus causes neuron cell death2013

    • Author(s)
      Suzuki H, Matsuoka M.
    • Organizer
      第86回日本薬理学会
    • Place of Presentation
      福岡 国際会議場
    • Data Source
      KAKENHI-PROJECT-23390059
  • [Presentation] SH3BP5 is essential for Humanin-mediated protection against Alzheimer's disease relevant toxicity2013

    • Author(s)
      Takeshita Y, Hashimoto Y, Uchino H, Matsuoka M
    • Organizer
      第86回日本薬理学会
    • Place of Presentation
      福岡 国際会議場
    • Data Source
      KAKENHI-PROJECT-23659784
  • [Presentation] SH3-binding protein 5 mediates the neuroprotective effect of Humanin by inhibiting c-Jun NH2-terminal kinase2013

    • Author(s)
      Hashimoto Y, Takeshita Y, Nawa M, Uchino H, Matsuoka M.
    • Organizer
      Society for Neuroscience 43rd annual meeting 2013
    • Place of Presentation
      アメリカ合衆国カリフォルニア州サンディエゴ市
    • Data Source
      KAKENHI-PROJECT-25460343
  • [Presentation] SH3BP5 is essential for Humanin-mediated protection against Alzheimer's disease-relevant toxicity2013

    • Author(s)
      竹下裕二、橋本祐一、内野博之、松岡正明
    • Organizer
      日本薬理学会第86回大会
    • Place of Presentation
      福岡国際会議場
    • Year and Date
      2013-03-23
    • Data Source
      KAKENHI-PROJECT-22590247
  • [Presentation] Amyotrophic lateral sclerosis-linked mutant VAPB enhances TDP-43-induced motor neuronal toxicity2012

    • Author(s)
      Suzuki H, Matsuoka M
    • Organizer
      日本薬理学会
    • Place of Presentation
      京都国際会館
    • Year and Date
      2012-03-16
    • Data Source
      KAKENHI-PROJECT-23390059
  • [Presentation] Decreased expression of BTBD10 in motor neurons may contribute to the ALS pathogenesis2012

    • Author(s)
      Nawa M, Matsuoka M
    • Organizer
      Society for Neuroscience. 42th annual meeting 2012
    • Place of Presentation
      New Orleans, USA
    • Data Source
      KAKENHI-PROJECT-23390059
  • [Presentation] Reduced expression of BTBD10, an Akt activator, leads to motor neuron death2012

    • Author(s)
      Nawa M, Kage-Nakadai E, Aiso S, Okamoto K, Mitani S, Matsuoka M
    • Organizer
      日本薬理学会
    • Place of Presentation
      京都国際会館
    • Year and Date
      2012-03-16
    • Data Source
      KAKENHI-PROJECT-23390059
  • [Presentation] MOCA is an integrator of the neuronal death signals that are activated by familial Alzheimer's disease-related mutants of amyloid β precursor protein and presenilins2011

    • Author(s)
      Tachi N, Hashimoto Y, Matsuoka M
    • Organizer
      Society for Neuroscience
    • Place of Presentation
      Washington, DC
    • Year and Date
      2011-11-14
    • Data Source
      KAKENHI-PROJECT-23390059
  • [Presentation] MOCA is an integrator of the neuronal death singnals,activated by familial Alzheimer' disease-relate mutants of amyloid β precursor protein and presenilins.2011

    • Author(s)
      橋本祐一、太知信之、松岡正明
    • Organizer
      第84回日本薬理学会
    • Place of Presentation
      横浜、日本
    • Year and Date
      2011-03-22
    • Data Source
      KAKENHI-PROJECT-20390072
  • [Presentation] Involvement of MOCA in neuronal cell death triggered by familial Alzheimer's disease-linked mutants of APP and presenilins.2011

    • Author(s)
      橋本祐一、太知信之、名和幹朗、松岡正明
    • Organizer
      日本薬理学会 第84回大会
    • Place of Presentation
      横浜
    • Year and Date
      2011-03-16
    • Data Source
      KAKENHI-PROJECT-22590247
  • [Presentation] Amyotrophic lateral sclerosis-linked mutant VAPB enhances TDP-43-induced motor neuronal toxicity2011

    • Author(s)
      Suzuki H, Matsuoka M
    • Organizer
      Society for Neuroscience
    • Place of Presentation
      Washington, DC
    • Year and Date
      2011-11-13
    • Data Source
      KAKENHI-PROJECT-23390059
  • [Presentation] Involvement of MOCA in Alzheimer ' s disease-relevant neuronal cell death via APP and presenilins2011

    • Author(s)
      Hashimoto Y, Tachi N, Matsuoka M
    • Organizer
      Society for Neuroscience 2011 Annual Meeting
    • Place of Presentation
      ワシントン D.C
    • Year and Date
      2011-11-12
    • Data Source
      KAKENHI-PROJECT-22590247
  • [Presentation] TDP-43-induced death is associated with altered regulation of BIM and BCL-XL and attenuated by caspase-mediated TDP-43 cleavage2010

    • Author(s)
      Suzuki H., Lee K., Matsuoka M.
    • Organizer
      The annual meeting of Society For Neuroscience
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2010-11-17
    • Data Source
      KAKENHI-PROJECT-20390072
  • [Presentation] Transforming Growth Factor β2 Level is Elevated in Neurons of Alzheimer's Disease's Brains.2010

    • Author(s)
      名和幹朗、野口敦、相磯貞和、松岡正明
    • Organizer
      第83回日本薬理学会
    • Place of Presentation
      大阪
    • Year and Date
      2010-03-17
    • Data Source
      KAKENHI-PROJECT-20390072
  • [Presentation] Development of neurotoxicity-blocking therapy for Alzheimer's disease using Humanin.2010

    • Author(s)
      Matsuoka M.
    • Organizer
      The 10^<th> Biennial Meeting of the Asia-Pacific Society for Neurochemistry 2010
    • Place of Presentation
      Phuket, Thailand
    • Year and Date
      2010-10-18
    • Data Source
      KAKENHI-PROJECT-20390072
  • [Presentation] TAG-1 inhibits neuronal cell death induced by interaction between TGF β2 and APP.2010

    • Author(s)
      太知信之、橋本祐一、名和幹朗、松岡正明
    • Organizer
      第83回日本薬理学会
    • Place of Presentation
      大阪
    • Year and Date
      2010-03-17
    • Data Source
      KAKENHI-PROJECT-20390072
  • [Presentation] TDP-43-induced death is associated with altered regulation of BIM and BCL-XL and attenuated by caspase-mediated TDP-43 cleavage.2010

    • Author(s)
      Suzuki H. Lee K. Matsuoka M.
    • Organizer
      The annual meeting of Society For Neuroscience
    • Place of Presentation
      San Diego
    • Data Source
      KAKENHI-PROJECT-20390072
  • [Presentation] Georg Christian Terstappen, and Andrea Caricasole VSTM2L is a novel secreted antagonist of the neuroprotective peptide humanin2009

    • Author(s)
      Lara Rossini, Hashimoto Y, Kurita M, Marco Gianfriddo, Carla Scali, Renza Roncarati, Davide Franceschini, Giuseppe Pollio, Lorenza Trabalzini, Matsuoka M
    • Organizer
      The annual meeting of Society For Neuroscience
    • Place of Presentation
      Chicago
    • Data Source
      KAKENHI-PROJECT-20390072
  • [Presentation] A novel secreted antagonist of the neuroprotective peptide Humanin.2009

    • Author(s)
      A.Caricasole, L.Rossini, Y.Hashimoto, M.Kurita, C.Scali, R.Roncarati, L.Trabalzini, M.Matsuoka, G.C.Terstappen.
    • Organizer
      Society for Neuroscience 39th annual meeting 2009
    • Place of Presentation
      Chicago
    • Year and Date
      2009-10-20
    • Data Source
      KAKENHI-PROJECT-20390072
  • [Presentation] The JAK2/STAT3 signaling axis mediates therapeutic effect of Colivelin on memory impairment related to Alzheimer's disease2008

    • Author(s)
      Yamada, M, Chiba, T, Sasabe, J, Terashita, K, Matsuoka, M, Aiso, S
    • Organizer
      The 81 th Annual Meeting of the Japanese Pharmacological Society
    • Place of Presentation
      Yokohama
    • Year and Date
      2008-03-17
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390077
  • [Presentation] The JAK2/STAT3 signaling axis mediates therapeutic effect of Colivelin on memory impairment related to Alzheimer's disease2008

    • Author(s)
      Yamada, M, Chiba, T, Sasabe, J, Terashita, K, Matsuoka, M, Aiso, S
    • Organizer
      The 81th Annual Meeting of the Japanese Pharmacological Society
    • Place of Presentation
      Yokohama
    • Year and Date
      2008-03-17
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590240
  • [Presentation] Nasal Colivelin treatment ameliorates Alzheimer's cognitive deficits via the JAK2/STAT3 axis2007

    • Author(s)
      Matsuoka M., et. al.
    • Organizer
      Keystone symposia: Molecular mechanisms of neurodegeneration
    • Place of Presentation
      Taos,New Mexico
    • Year and Date
      2007-01-19
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18390077
  • [Presentation] Humanin inhibits neuronal death via a CNTF receptor alpha/ WSX-1/gp130 complex2007

    • Author(s)
      Hashimoto, Y, Kurita, M, Nishimoto, I, Aiso, S, Matsuoka, M
    • Organizer
      Society for Neuroscience 37th Annual Meeting 2007
    • Place of Presentation
      San Diego
    • Year and Date
      2007-11-06
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390077
  • [Presentation] Nasal Colivelin treatment ameliorates Alzheimer's cognitive deficits via the JAK2/STAT3 axis2007

    • Author(s)
      Matsuoka, M, Yamada, M, Chiba, T, Sasabe, J, Sato, M, Nishimoto, I, Aiso, S
    • Organizer
      Keystone symposia : Molecular mechanisms of neurodegeneration
    • Place of Presentation
      Taos, New Mexico
    • Year and Date
      2007-01-19
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390077
  • [Presentation] The JAK2/STAT3 signaling axis regulates memory in Alzheimer's disease2007

    • Author(s)
      Chiba, T, Yamada, M, Sasabe, J, Terashita, K, Aiso, S, Matsuoka, M
    • Organizer
      Society for Neuroscience 37th Annual Meeting 2007
    • Place of Presentation
      San Diego
    • Year and Date
      2007-11-06
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590240
  • [Presentation] Nasal Colivelin treatment ameliorates Alzheimer's cognitive deficits via the JAK2/STAT3 axis2007

    • Author(s)
      Yamada, M, Chiba, T, Sasabe J, Sato, M, Nishimoto, IAiso, S, Matsuoka, M
    • Organizer
      The 80th Annual Meeting of the Japanese Pharmacological Society
    • Place of Presentation
      Nagoya
    • Year and Date
      2007-03-16
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390077
  • [Presentation] The JAK2/STAT3 signaling axis regulates memory in Alzheimer's disease2007

    • Author(s)
      Chiba, T, Yamada, M, Sasabe, J, Terashita, K, Aiso, S, Matsuoka, M
    • Organizer
      Society for Neuroscience 37th Annual Meeting 2007
    • Place of Presentation
      San Diego
    • Year and Date
      2007-11-06
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390077
  • [Presentation] D-serine exacerbates glutamate excitotoxicity in ALS2007

    • Author(s)
      Sasabe, J, Chiba, T, Yamada, M, Okamoto, K, Nishimoto, I, Aiso, S, Matsuoka, M
    • Organizer
      18th International Symposia on ALS/MND (motor neuron disease)
    • Place of Presentation
      Toronto, Canada
    • Year and Date
      2007-12-01
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390077
  • [Presentation] Development of a femtomolar-acting Humanin derivative named Colive attaching ADNF to its N terminus : characterization of Colivelin-mediate neuroprotection against Alzheimer's disease-relevant insults in vitro ar vivo2007

    • Author(s)
      Yamada, M, Chiba, T, Sato, M, Sasabe, J, Terashita, K, Aiso, S, Nishimoto, I, Matsuoka, M
    • Organizer
      The 16th The Japanese Youg Researcher's Society of Neurobehavioral Pharmacology
    • Place of Presentation
      Nagoya
    • Year and Date
      2007-03-13
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390077
  • [Presentation] Amyotrophic lateral sclerosis-linked pro56ser vesicle-associated membrane protein-associated protein impairs unfolded protein response.2007

    • Author(s)
      Kanekura, K, Suzuki, H, Nishimoto, I, Levine, T, Kohno, K, Suzuki, N, Aiso, S, Matsuoka, M
    • Organizer
      18th International Symposia on ALS/MND (motor neuron disease)
    • Place of Presentation
      Toronto, Canada
    • Year and Date
      2007-12-01
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390077
  • [Presentation] Nasal Colivelin treatment for Alzheimer's disease-related memory impairment2007

    • Author(s)
      Yamada, M, Chiba, T, Sasabe, J, Terashita, K, Aiso, S, Matsuoka, M
    • Organizer
      Society for Neuroscience 37th Annual Meeting 2007
    • Place of Presentation
      San Diego
    • Year and Date
      2007-11-03
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590240
  • [Presentation] Identification of an alternatively spliced soluble WSX-1 as a functional anti-Alzheimer disease rescue factor Humanin2007

    • Author(s)
      Hashimoto, Y, Chiba, T, Nishimoto, I, Aiso, S, Matsuoka, M
    • Organizer
      The 80th Annual Meeting of the Japanese Pharmacological Society
    • Place of Presentation
      Nagoya
    • Year and Date
      2007-03-16
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390077
  • [Presentation] Nasal Colivelin treatment for Alzheimer's disease-related memory impairment2007

    • Author(s)
      Yamada M, Chiba T, Sasabe J, Texashita K, Aiso S, Matsuoka M
    • Organizer
      北米神経学会
    • Place of Presentation
      米国サンディエゴ
    • Year and Date
      2007-11-03
    • Data Source
      KAKENHI-PROJECT-18590240
  • [Presentation] Development of a femtomolar-acting Humanin derivative named Colivelin By attaching ADNF to its N terminus : characterization of Colivelin-Mediated neuroprotection against Alzheimer's disease-relevant insults in vitro and in vivo2007

    • Author(s)
      Yamada, M, Chiba, T, Sato, M, Sasabe, J, Terashita, K, Also, S, Nishimoto, I, Matsuoka, M
    • Organizer
      The 16th The Japanese Youg Researcher's Society of Neurobehavioral Pharmacology
    • Place of Presentation
      Nagoya
    • Year and Date
      2007-03-13
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590240
  • [Presentation] The JAK2/STAT3 signaling axis regulates memory in Alzheimer's disease2007

    • Author(s)
      Chiba T, Yamada M, Sasabe J, Terashita K, Aiso S, Matsuoka M
    • Organizer
      北米神経学会
    • Place of Presentation
      米国サンディエゴ
    • Year and Date
      2007-11-06
    • Data Source
      KAKENHI-PROJECT-18590240
  • [Presentation] Intranasally administered Colivelin exhibits neuroprotective effect on cholinergic neurons via the JAK/STAT axis2006

    • Author(s)
      Chiba, T, Yamada, M, Sasabe, J, Sato, M, Nishimoto, I, Aiso, S, Matsuoka, M
    • Organizer
      Society for Neuroscience 36th Annual Meeting 2006
    • Place of Presentation
      Atlanta
    • Year and Date
      2006-10-16
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390077
  • [Presentation] Characterization of Colivelin-mediated neuroprotection against ALS -relevant insults2006

    • Author(s)
      Chiba, T, Yamada, M, Sasabe, J, Nishimoto, I, Aiso, S, Matsuoka, M
    • Organizer
      International Symposia on ALS/MND (motor neuron disease)
    • Place of Presentation
      Yokohama
    • Year and Date
      2006-12-01
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390077
  • [Presentation] Elimination of apoptosis signal-regulating kinase 1 gene from ALS model mice attenuates disease progression2006

    • Author(s)
      Sasabe, J, Chiba, T, Yamada, M, Nishimoto, I, Aiso, S, Matsuoka, M
    • Organizer
      International Symposia on ALS/MND (motor neuron disease)
    • Place of Presentation
      Yokohama
    • Year and Date
      2006-12-01
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390077
  • [Presentation] Humanin and Colivelin, Neuroprotectors against Alzheimer's Disease2006

    • Author(s)
      Masaaki, Matsuoka
    • Organizer
      Joint Meeting Summer neuropeptide Conference and The European neuropeptide Club
    • Place of Presentation
      Miami
    • Year and Date
      2006-06-29
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390077
  • [Presentation] Humanin and Colivelin,Neuroprotectors against Alzheimer's Disease2006

    • Author(s)
      Masaaki Matsuoka
    • Organizer
      Joint Meeting Summer neuropeptide Conference and The Euronean neuropeptide Club
    • Place of Presentation
      Miami
    • Year and Date
      2006-06-29
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18390077
  • [Presentation] Characterization of amyotrophic lateral sclerosis-linked P56s-vesicular membrane-associated Protein-associated protein B2006

    • Author(s)
      Kanekura, K, Nishimoto, I, Aiso, S, Matsuoka, M
    • Organizer
      membrane-associated Protein-associated protein B
    • Place of Presentation
      Atlanta
    • Year and Date
      2006-10-17
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390077
  • [Presentation] Nasal Colivelin treatment ameliorates Alzheimer's congnitive deficits via the JAK/STAT axis2006

    • Author(s)
      Yamada, M, Chiba, T, Sasabe, J, Sato, M, Nishimoto, I, Aiso S, Matsuoka, M
    • Organizer
      Neuron and disease -The 4th Neuron Satellite Meeting 2006
    • Place of Presentation
      Atlanta
    • Year and Date
      2006-10-13
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390077
  • [Presentation] Characterization of amyotrophic lateral sclerosis-linked Pro56Ser mutation of vesicle-associated membrane protein-associated protein B (VAPB/ALS8)2006

    • Author(s)
      Kanekura, K, Nishimoto, I, Aiso, S, Matsuoka, M
    • Organizer
      International Symposia on ALS/MND (motor neuron disease)
    • Place of Presentation
      Yokohama
    • Year and Date
      2006-12-02
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390077
  • 1.  NISHIMOTO Ikuo (80180652)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 2.  NIIKURA Takako (10301491)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 3.  MATSUDA Shuji (70296721)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 4.  HASHIMOTO Yuuichi (00317330)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 13 results
  • 5.  CHIBA Tomohiro (60398617)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 26 results
  • 6.  YAMOCHI Tadanori (80306844)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 7.  KOUYAMA Keisuke (30296553)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 8.  Hanyu Haruo (10228520)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 9.  IWAMOTO Toshihiko (10246168)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  UMAHARA Takahiko (70266477)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  TERASHITA Kenzo (00163915)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 10 results
  • 12.  喜多 淑子 (00327496)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  安川 孝史 (60291936)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  田島 裕久 (50306833)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  石井 賢二 (10231135)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  清水 聰一郎 (10385031)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  櫻井 博文 (60235223)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  金高 秀和 (90385021)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  鈴木 宏昌
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 20.  桑迫 香奈子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 21.  内藤 幹彦
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 22.  草苅 伸也
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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