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Ishikawa Satoko  石川 さと子

ORCIDConnect your ORCID iD *help
… Alternative Names

ISHIKAWA Satoko  石川 さと子

石川 さと子  イシカワ サトコ

鵜川 さと子  ウカワ サトコ

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Researcher Number 70223518
Other IDs
Affiliation (Current) 2025: 慶應義塾大学, 薬学部(芝共立), 教授
Affiliation (based on the past Project Information) *help 1997 – 2004: 共立薬科大学, 薬学部, 助手
1993 – 1995: 共立薬科大学, 薬学部, 助手
1991: 共立薬科大学, 薬学部, 助手
Review Section/Research Field
Except Principal Investigator
Chemical pharmacy / Environmental pharmacy / Environmental pharmacy / 医薬分子機能学
Keywords
Except Principal Investigator
代謝活性化 / N-ニトロソジアルキルアミン / 突然変異原性 / Fenton reagent / metabolic activation / 一酸化窒素 / 変異原性 / シトクロムP450 / ポルフィリン金属錯体 / reactive oxygen species … More / mutagenicity / N-nitrosodialkylamines / Fenton試薬 / フェントン試薬 / ヒドロキシルラジカル / 酸化剤 / 化学モデル系 / DNA損傷 / 突然変異原生 / ヒドロキシラジカル / Fe^<2+> -Cu^<2+> -H_2O_2 system / 活性酸素種 / 鉄-銅-過酸化水素系 / mutagen / oxidant / metal porphyrin complex / carcinogen / N-nitrosodialkylamine / DNAアルキル化 / 化学的酸化モデル系 / 変異原 / 発がん物質 / Antioxidant / Tocopherol / Ascorbic acid / Vitamin E / Vitamin C / 痛風治療薬 / キサンチンオキシダーゼ / reductic acid / 抗酸化剤 / トコフェロール / アスコルビン酸 / ビタミンE / ビタミンC / 制がん性化合物 / アポトーシス / p53 / 抗腫瘍活性スクリーニング / 酸化 / 活性酸素 / ニトロサミノラジカル / 不安定代謝中間体 / 金属ポルフィリン / 環境内化学発がん物質 / Salmonella typhimurium YG7108 / 脱アルキル化反応 / シトクロムP-450モデル / 環境内発がん物質 / U937 / HLー60 / ベンズアミド / ヒドロキシメチルアミド / 突然変異 / 分化誘導 Less
  • Research Projects

    (10 results)
  • Research Products

    (10 results)
  • Co-Researchers

    (5 People)
  •  Novel metabolic pathway for activation of carcinogenic N-nitroso compounds by reactive oxygen species

    • Principal Investigator
      MOCHIZUKI Masataka
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Environmental pharmacy
    • Research Institution
      Kyoritsu University of Pharmacy
  •  Mechanism of activation of carcinogenic N-nitroso compounds by reactive oxygen species

    • Principal Investigator
      MOCHIZUKI Masataka
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Environmental pharmacy
    • Research Institution
      Kyoritsu College of Pharmacy
  •  Synthesis and antioxidant activity of vitamin C analogs and vitamin E analogs

    • Principal Investigator
      MASHINO Tadahiko
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      医薬分子機能学
    • Research Institution
      Kyoritsu College of Pharmacy
  •  Activation mechanism of carcinogenic N-nitrosodialkyamines by chemical model for cytochrome P450

    • Principal Investigator
      MOCHIZUKI Masataka
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Environmental pharmacy
    • Research Institution
      Kyoritsu University of Pharmacy
  •  p53関連遺伝子の発現を指標とする抗腫瘍活性の新検索システムの開発と応用

    • Principal Investigator
      望月 正隆
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Kyoritsu University of Pharmacy
  •  活性酸素種によるN-ニトロソ化合物の分解と変異原性発現の分子機構

    • Principal Investigator
      望月 正隆
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Chemical pharmacy
    • Research Institution
      Kyoritsu University of Pharmacy
  •  シトクロムP450化学モデル系によるN-ニトロン化合物の代謝活性化分子機構の解明

    • Principal Investigator
      望月 正隆
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Chemical pharmacy
    • Research Institution
      Kyoritsu University of Pharmacy
  •  金属ポルフィリン-酸化剤によるN-ニトロソジアルキルアミンの代謝活性化

    • Principal Investigator
      望月 正隆
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Chemical pharmacy
    • Research Institution
      Kyoritsu University of Pharmacy
  •  シトクロムP-450モデルによるN-ニトロソ化合物の酸化的代謝反応

    • Principal Investigator
      望月 正隆
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Chemical pharmacy
    • Research Institution
      Kyoritsu University of Pharmacy
  •  Nーヒドロキシメチルアミド化合物の生物活性の作用機構の解明

    • Principal Investigator
      MOCHIZUKI Masataka
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Chemical pharmacy
    • Research Institution
      Kyoritsu University of Pharmacy

All 2004 2003 2000 1999

All Journal Article

  • [Journal Article] Synthesis and properties of bifunctional chloroalkyl-nitrosamines with an intercalating moiety.2004

    • Author(s)
      Ishikawa S, Tajima M, Mochizuki M.
    • Journal Title

      Bioorg Med Chem 12

      Pages: 3791-3796

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590113
  • [Journal Article] Synthesis and properties of bifunctional chloroalkyl nitrosamines with an intercalating moiety.2004

    • Author(s)
      Ishikawa S, Tajima M, Mochizuki M.
    • Journal Title

      Bioorg Med Chem 12

      Pages: 3791-3796

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590113
  • [Journal Article] Sunthesis and properties of bifunctional chloroalkyl nitrosamines with an intercalating moiety.2004

    • Author(s)
      Ishikawa S, Tajima M, Mochizuki M.
    • Journal Title

      Bioorganic & Medicinal Chemistry 12

      Pages: 3791-3796

    • Data Source
      KAKENHI-PROJECT-15590113
  • [Journal Article] Mutagenicity and cross-linking activity of chloroalkylnitrosamines, possible new antitumor lead compounds.2003

    • Author(s)
      Ishikawa S, Mochizuki M.
    • Journal Title

      Mutagenesis 18

      Pages: 331-335

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590113
  • [Journal Article] A practical approach for the chemical synthesis of 2'-deoxyguanosine-C8 adducts with mutagenic/carcinogenic amino- or nitro-arenes.2003

    • Author(s)
      Takamura-Enya T, Ishikawa S, Mochizuki M, Wakabayashi K.
    • Journal Title

      Tetrahedron Lett 44

      Pages: 5969-5973

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590113
  • [Journal Article] Mutagenicity and cross-linking activity of chloroalkylnitros amines, possible new antitumor lead compounds.2003

    • Author(s)
      Ishikawa S, Mochizuki M.
    • Journal Title

      Mutagenesis 18

      Pages: 331-335

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590113
  • [Journal Article] Synthesis and properties of novel bifunctional nitrosamines with ω-chloroalkyl groups2000

    • Author(s)
      Ishikawa S., Saitoh N., Mochizuki M.
    • Journal Title

      Chem.Pharm.Bull 48・10

      Pages: 1500-1503

    • NAID

      110003635316

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-11672229
  • [Journal Article] Synthesis and properties of novel bifunctional nitrosamines with ω-chloroalkyl groups2000

    • Author(s)
      Ishikawa S., Saitoh N., Mochizuki M.
    • Journal Title

      Chem.Pharm.Bull. 48(10)

      Pages: 1500-1503

    • NAID

      110003635316

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-11672229
  • [Journal Article] Mutagenicity of potassium alkanediazotates in Chinese hamster V79 cells and their alkylating activity1999

    • Author(s)
      Ukawa-Ishikawa S., Seki M., Mochizuki M.
    • Journal Title

      Biol.Pharm.Bull. 22・6

      Pages: 577-581

    • NAID

      110003639715

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-11672229
  • [Journal Article] Mutagenicity of potassium alkanediazotates in Chinese hamster V79 cells and their alkylating activity1999

    • Author(s)
      Ukawa-Ishikawa S., Seki M., Mochizuki M.
    • Journal Title

      Biol.Pharm.Bull. 22(6)

      Pages: 577-581

    • NAID

      110003639715

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-11672229
  • 1.  MOCHIZUKI Masataka (10072414)
    # of Collaborated Projects: 9 results
    # of Collaborated Products: 10 results
  • 2.  INAMI Keiko (00271247)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 3.  堤 のぞみ (00255382)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  MASHINO Tadahiko (90165697)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  武田 啓 (90227025)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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