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KOITO ATSUSHI  小糸 厚

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… Alternative Names

KOITO Atsushi  小糸 厚

小糸 厚  コイト アツシ

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Researcher Number 70231305
Other IDs
External Links
Affiliation (based on the past Project Information) *help 2013: 熊本大学, 大学院生命科学研究部, 研究員
2013: 熊本大学, 生命科学研究部, 研究員
2012: 熊本大学, 生命科学研究部, 教授
2011: 熊本大学, 生命科学研究部, 特任教授
1999: AIDS Research Center, Kumamoto University, Asso. Professor, エイズ学研究センター, 講師
1995 – 1998: 筑波大学, 基礎医学系, 講師
1991: 理化学研究所, フロンティア研究システム, 研究員
Review Section/Research Field
Principal Investigator
Virology / Biological Sciences / Virology
Keywords
Principal Investigator
HTLV-I / レセプター / HTLV-1 / エンベロープ / レトロウイルス / 組み込み / マウスリンパ球 / マウスモデル / Transgenic mouse / Integration … More / Mouse lymphocytes / Receptor / HTLV-I 感染 / HTLV-l / トランスジェニックマウス / レセプター分子 / HIV-vector / Envelope / Tropism / Retrovirus / パッケージング / Pseudotype / 組換えレトロウイルス / レトロウィルス / HIVベクター / HTLV・I / トロピズム / APOBEC / ゲノム / 小動物モデル / HIV / レトロエレメント / シチジン脱アミノ化酵素 / リコンビナントgp120 / 核移行 / HIV-1 / CD4 / ケモカインレセプター / HIV感染 … More
Except Principal Investigator
ケモカインレセプター / CD4 / サイトカイン / マウスモデル / HIV感染 / 血液幹細胞 / エリスロポエチンレセプタ- / CD34 / Cーkit Less
  • Research Projects

    (7 results)
  • Research Products

    (40 results)
  • Co-Researchers

    (7 People)
  •  Research in anti-retroviral intrinsic immunity using APOBEC1 knock-out micePrincipal Investigator

    • Principal Investigator
      KOITO ATSUSHI
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Virology
    • Research Institution
      Kumamoto University
  •  マウスモデルによるHIV感染ならびに発症機構の解析Principal Investigator

    • Principal Investigator
      小糸 厚
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Review Section
      Biological Sciences
    • Research Institution
      Kumamoto University
  •  マウスモデルによるHIV感染ならびに発症機構の解析Principal Investigator

    • Principal Investigator
      小糸 厚
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Review Section
      Biological Sciences
    • Research Institution
      University of Tsukuba
  •  Study of Generated trasgenic mice predominantly expressing T-tropic HIV-1Principal Investigator

    • Principal Investigator
      KOITO Atsushi
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Virology
    • Research Institution
      Kumamoto University
      University of Tsukuba
  •  動物モデルによるHIV感染ならびに発症機構の解析

    • Principal Investigator
      中内 啓光
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      University of Tsukuba
  •  Approach to identify cellular factor(s) which determine spieces-and tissue-specificity of HTLV-infectionPrincipal Investigator

    • Principal Investigator
      KOITO Atsushi
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Virology
    • Research Institution
      Institute of Basic Medical Science, Tsukuba University
  •  造血幹細胞に発現されている細胞表面機能分子の分子生物学的解析

    • Principal Investigator
      NAKAUCHI Hiromitsu
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The Institute of Physical and Chemical Research

All 2013 2012 2011

All Journal Article Presentation Book

  • [Book] Intrinsic immunity by APOBEC family of cytidine deaminases against retrotransposons, in Sequence and Genome Analysis II Bacteria, Viruses and Metabolic Pathways (ed. iConcept Press Ltd)2013

    • Author(s)
      Koito A
    • Total Pages
      29
    • Publisher
      iConcept Press Ltd
    • Data Source
      KAKENHI-PROJECT-23590546
  • [Book] Intrinsic immunity by APOBEC family of cytidine deaminases against retrotransposons, in Introduction to Sequence and Genome Analysis (ed. Fung G), iConcept Press, ISBN, NY, (In press).2013

    • Author(s)
      Koito A
    • Total Pages
      20
    • Publisher
      iConcept Press, ISBN, NY.
    • Data Source
      KAKENHI-PROJECT-23590546
  • [Journal Article] Intrinsic immunity by APOBEC family of cytidine deaminases against retrotransposons, in Sequence and Genome Analysis II–Bacteria2013

    • Author(s)
      Koito A.
    • Journal Title

      Viruses and Metabolic Pathways (ed. iConcept Press Ltd)

      Pages: 96-124

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590546
  • [Journal Article] Intrinsic immunity against retrotransposons by APOBEC cytidine deaminases.2013

    • Author(s)
      Koito A, Ikeda T
    • Journal Title

      Front. Microbiol.

      Volume: 4 Pages: 28-28

    • DOI

      10.3389/fmicb.2013.00028

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590546
  • [Journal Article] Retroviruses, retroelements and their restrictions.2013

    • Author(s)
      Koito A, Ishizaka Y
    • Journal Title

      Front. Microbiol.

      Volume: 4 Pages: 197-197

    • DOI

      10.3389/fmicb.2013.00197

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590546
  • [Journal Article] GANP interacts with APOBEC3G and facilitates its encapsidation into the virions to reduce HIV-1 infectivity2013

    • Author(s)
      Maeda K, Almofty SA (co-first author), Singh SK, Eid MMA, Shimoda M, Ikeda T, Koito A, Pham P, Goodman MF, Sakaguchi N
    • Journal Title

      J. Immunol

      Volume: 191 Issue: 12 Pages: 6030-6039

    • DOI

      10.4049/jimmunol.1302057

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390122, KAKENHI-PROJECT-23590546, KAKENHI-PROJECT-24659224
  • [Journal Article] Intrinsic immunity against retrotransposons by APOBEC cytidine deaminases2012

    • Author(s)
      Koito A, Ikeda T
    • Journal Title

      Front. Microbiol.

      Volume: .

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590546
  • [Journal Article] Apolipoprotein B mRNA-editing, catalytic polypeptide cytidine deaminases and retroviral restriction2012

    • Author(s)
      Koito A, and Ikeda T.
    • Journal Title

      Wiley Interdisciplinary Reviews (WIREs) RNA

      Volume: 3 Issue: 4 Pages: 529-541

    • DOI

      10.1002/wrna.1117

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590546
  • [Journal Article] Intrinsic restriction activity by apolipoprotein B mRNA editing enzyme APOBEC1 against the mobility of autonomous retrotransposons2011

    • Author(s)
      Ikeda, T., Abd El Galil, K., Tokunaga, K., Maeda, K., Sata, T., Sakaguchi, N., Harada, S., Heidmann, T., Koito, A.
    • Journal Title

      Nucleic Acids Res

      Volume: 39 Issue: 13 Pages: 5538-54

    • DOI

      10.1093/nar/gkr124

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590428, KAKENHI-PROJECT-23590546
  • [Journal Article] Intrinsic restriction activity by AID/APOBEC family of enzymes against the mobility of retroelements2011

    • Author(s)
      Koito A, Ikeda T
    • Journal Title

      Moblile Genetic Elements

      Volume: 1 Issue: 3 Pages: 197-202

    • DOI

      10.4161/mge.1.3.17430

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22890144, KAKENHI-PROJECT-23590546
  • [Journal Article] Vipirinin, a coumarin-based HIV-1 Vpr inhibitor, interacts with a hydrophobic region of VPR2011

    • Author(s)
      Ong E. B., et al.
    • Journal Title

      J Biol Chem.

      Volume: 286 Issue: 16 Pages: 14049-14056

    • DOI

      10.1074/jbc.m110.185397

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-19057005, KAKENHI-PROJECT-21603017, KAKENHI-PROJECT-23590546
  • [Presentation] Role of mammalian TREX-2 component GANP in HIV-1 infection2013

    • Author(s)
      Maeda K, Almofty SA, Singh SK, Eid MMA, Shimoda M, Ikeda T, Shida H, Koito A, Pham P, Goodman MF, and Sakaguchi N.
    • Organizer
      14th. Kumamoto AIDS Seminar.
    • Place of Presentation
      Aso Resort Grandvrio Hotel, Kumamoto, Japan
    • Data Source
      KAKENHI-PROJECT-23590546
  • [Presentation] Role of mammalian TREX-2 component GANP in HIV-1 infection2013

    • Author(s)
      Maeda K, Almofty SA, Singh SK, Eid MMA, Shimoda M, Ikeda T, Shida H, Koito A, Pham P, Goodman MF, and Sakaguchi N.
    • Organizer
      14th. Kumamoto AIDS Seminar
    • Place of Presentation
      Kumamoto, Japan
    • Data Source
      KAKENHI-PROJECT-23590546
  • [Presentation] HIV感染経路における宿主因子GANPの役割2013

    • Author(s)
      前田和彦、Almofty SA, Singh SK, Eid MMA, 下田真唯子, 川畑輝哉, 池田輝政、小糸 厚、坂口薫雄
    • Organizer
      第27回日本エイズ学会学術集会.
    • Place of Presentation
      市民会館崇城大学ホール (熊本)
    • Data Source
      KAKENHI-PROJECT-23590546
  • [Presentation] HIV感染経路における宿主因子GANPの役割2013

    • Author(s)
      前田和彦、Almofty SA, Singh SK, Eid MMA,下田真唯子,川畑輝哉,池田輝政、小糸厚、坂口薫雄
    • Organizer
      第27回日本エイズ学会学術集会
    • Place of Presentation
      市民会館崇城大学ホール(熊本)
    • Data Source
      KAKENHI-PROJECT-23590546
  • [Presentation] Intrinsic restriction activity by APOBEC enzymes against HIV and retroelements2012

    • Author(s)
      小糸 厚
    • Organizer
      第8回日中交流国際生命科学シンポジウム
    • Place of Presentation
      熊本大学 医学教育図書棟 第一講義室
    • Invited
    • Data Source
      KAKENHI-PROJECT-23590546
  • [Presentation] Intrinsic restriction activity by APOBEC enzymes against HIV and retroelement2012

    • Author(s)
      Koito A, Ikeda T.
    • Organizer
      4th International Conference on Drug Discovery & Therapy, Hot Topics in HIV Research
    • Place of Presentation
      Dubai, UAE(教育講演)
    • Data Source
      KAKENHI-PROJECT-23590546
  • [Presentation] APOBEC cytidine deaminase as a player of intrinsic immunity against HIV and retroelements2012

    • Author(s)
      Koito A, Ikeda T
    • Organizer
      BIT’s 2nd Annual World Congress of Molecular & Cell Biology (CMCB)
    • Place of Presentation
      北京, 中国
    • Invited
    • Data Source
      KAKENHI-PROJECT-23590546
  • [Presentation] 有袋類APOBEC1の抗レトロウイルス・レトロエレメント活性の解析2012

    • Author(s)
      池田輝政、福田和美、小糸 厚
    • Organizer
      第60回日本ウイルス学会学術集会総会
    • Place of Presentation
      グランキューブ大阪 (大阪国際会議場).
    • Data Source
      KAKENHI-PROJECT-23590546
  • [Presentation] APOBEC1 studies demonstrate the importance of a C-terminal region in HIV-1 restriction2012

    • Author(s)
      Ikeda T, Koito A
    • Organizer
      Cold Spring Harbor Laboratory 2012 Meeting on Retroviruses
    • Place of Presentation
      Cold Spring Harbor, NY, USA
    • Data Source
      KAKENHI-PROJECT-23590546
  • [Presentation] APOBEC cytidine deaminase as a player of intrinsic immunity against HIV and retroelements2012

    • Author(s)
      Koito A, Ikeda T.
    • Organizer
      BIT's 2nd Annual World Congress of Molecular & Cell Biology (CMCB)
    • Place of Presentation
      Beijing, China
    • Invited
    • Data Source
      KAKENHI-PROJECT-23590546
  • [Presentation] APOBEC3GのHIV-1粒子内への取り込みを制御する宿主因子GANP2012

    • Author(s)
      前田和彦、Sarah Ameen Almofty、Shailendra Kumar Singh、Mohammed Mansour Abbas Eid、下田真唯子、池田輝政、小糸 厚、坂口薫雄
    • Organizer
      第26回日本エイズ学会学術集会総会
    • Place of Presentation
      慶應義塾大学 日吉キャンパス; 横浜
    • Data Source
      KAKENHI-PROJECT-23590546
  • [Presentation] GANPを介したAPOBEC3Gの抗HIV感染阻止機構の解析2012

    • Author(s)
      前田和彦、Almofty SA, Singh SK, Eid MMA,下田真唯子,池田輝政、小糸厚、坂口薫雄
    • Organizer
      第26回日本エイズ学会学術集会
    • Place of Presentation
      慶応義塾大学日吉キャンパス(横浜)
    • Data Source
      KAKENHI-PROJECT-23590546
  • [Presentation] 有袋類APOBEC1の抗レトロウイルス・レトロエレメント活性の解析2012

    • Author(s)
      池田輝政、小糸厚
    • Organizer
      第60回日本ウイルス学会学術集会
    • Place of Presentation
      グランキューブ大阪(大阪)
    • Data Source
      KAKENHI-PROJECT-23590546
  • [Presentation] Intrinsic restriction activity by APOBEC enzymes against HIV and retroelement2012

    • Author(s)
      Koito A, Ikeda T
    • Organizer
      4th International Conference on Drug Discovery & Therapy, Hot Topics in HIV Research(招待講演)
    • Place of Presentation
      Dubai, UAE
    • Data Source
      KAKENHI-PROJECT-23590546
  • [Presentation] Mamalian TREX-2 component GANP is involved in HIV-1 mRNA export2012

    • Author(s)
      Maeda K, Almofty SA, Singh SK, Eid MMA, Shimoda M, Ikeda T, Shida H, Koito A, Pham P, Goodman MF, and Sakaguchi N.
    • Organizer
      13th. Kumamoto AIDS Seminar GCOE Joint International Symposium
    • Place of Presentation
      Kumamoto, Japan
    • Data Source
      KAKENHI-PROJECT-23590546
  • [Presentation] Intrinsic restriction activity by APOBEC cytidine deaminases against the mobility of retroelements2011

    • Author(s)
      Koito A, Ikeda T.
    • Organizer
      BIT's 1^<st> Annual World Congress of Molecular & Cell Biology (CMCB)
    • Place of Presentation
      Beijing, China
    • Invited
    • Data Source
      KAKENHI-PROJECT-23590546
  • [Presentation] APOBEC3GのHIV-1粒子内への取り込みを制御する宿主因子GANP2011

    • Author(s)
      前田和彦、Kumar SS、Ameen AS、Abbas EMM、池田輝政、小糸 厚、坂口薫雄
    • Organizer
      第25回日本エイズ学会学術集会総会
    • Place of Presentation
      ハイアット リージェンシー東京
    • Data Source
      KAKENHI-PROJECT-23590546
  • [Presentation] Retrovirus, retroelement restrictions by APOBEC enzymes2011

    • Author(s)
      Koito A, Ikeda T.
    • Organizer
      12th. Kumamoto AIDS Seminar GCOE Joint International Symposium
    • Place of Presentation
      Kumamoto, Japan
    • Data Source
      KAKENHI-PROJECT-23590546
  • [Presentation] シチジン脱アミノ化酵素によるレトロウイルス・レトロエレメントの制御2011

    • Author(s)
      小糸 厚
    • Organizer
      同仁化学研究所 フォーラム・イン・ドージン, RNAの識別と管理―自己、異常な自己、そして非自己.(招待講演)
    • Place of Presentation
      熊本ホテルキャッスル
    • Year and Date
      2011-11-04
    • Data Source
      KAKENHI-PROJECT-23590546
  • [Presentation] キメラタンパク質を用いたAPOBEC1の抗HIV-1活性に関する責任部位の機能解析2011

    • Author(s)
      池田輝政、小糸厚
    • Organizer
      第25回日本エイズ学会学術集会
    • Place of Presentation
      ハイアットリージェンシー東京(東京)
    • Data Source
      KAKENHI-PROJECT-23590546
  • [Presentation] シチジン脱アミノ化酵素によるレトロウイルス・レトロエレメントの制御2011

    • Author(s)
      小糸厚
    • Organizer
      同仁化学研究所フォーラム・イン・ドージン, RNAの識別と管理―自己、異常な自己、そして非自己
    • Place of Presentation
      熊本ホテルキャッスル(熊本)
    • Year and Date
      2011-11-04
    • Invited
    • Data Source
      KAKENHI-PROJECT-23590546
  • [Presentation] Identification of the functional region required for anti-HIV-1 activity of APOBEC12011

    • Author(s)
      Ikeda T, Koito A.
    • Organizer
      Cold Spring Harbor Laboratory, Meeting on Retroviruses
    • Place of Presentation
      Cold Spring Harbor, NY USA
    • Data Source
      KAKENHI-PROJECT-23590546
  • [Presentation] APOBEC3GのHIV-1粒子内への取り込みを制御する宿主因子GANP2011

    • Author(s)
      前田和彦、Kumar SS、Ameen AS、Abbas EMM、池田輝政、小糸厚、坂口薫雄
    • Organizer
      第25回日本エイズ学会学術集会
    • Place of Presentation
      ハイアットリージェンシー東京(東京)
    • Data Source
      KAKENHI-PROJECT-23590546
  • [Presentation] Intrinsic restriction activity by apoB mRNA editing enzyme APOBEC1 against the mobility of retroelements2011

    • Author(s)
      Koito A, Ikeda T.
    • Organizer
      Frontiers of Retrovirology Conference, Complex retroviruses, retroelements and their hosts
    • Place of Presentation
      Amsterdam, Netherlands
    • Data Source
      KAKENHI-PROJECT-23590546
  • [Presentation] GANP promotes APOBEC3G encapsidation in virions to reduce viral infectivity2011

    • Author(s)
      Maeda K, Singh SK, Ameen AS, Eid MMA, Ikeda T, Koito A, Pham P, Goodman MF, Sakaguchi N.
    • Organizer
      12th. Kumamoto AIDS Seminar GCOE Joint International Symposium
    • Place of Presentation
      Kumamoto, Japan
    • Data Source
      KAKENHI-PROJECT-23590546
  • [Presentation] GANP associated with HIV-1 RNA export is encapsidated with Apobec3G into virion cores2011

    • Author(s)
      Maeda K, Singh SK, Sarah A, Eid MM, Ikeda T, Pham P, Goodman MF, Koito A, Sakaguchi N.
    • Organizer
      Cold Spring Harbor Laboratory, Meeting on Retroviruses
    • Place of Presentation
      Cold Spring Harbor, NY USA
    • Data Source
      KAKENHI-PROJECT-23590546
  • [Presentation] Identification of the functional region required for anti-HIV-1 activity of APOBEC12011

    • Author(s)
      Ikeda T, Koito A.
    • Organizer
      XV International Congress of Virology
    • Place of Presentation
      Sapporo, Japan
    • Data Source
      KAKENHI-PROJECT-23590546
  • [Presentation] Intrinsic restriction activity by APOBEC cytidine deaminases against the mobility of retroelements2011

    • Author(s)
      Koito A, Ikeda T
    • Organizer
      BIT’s 1st Annual World Congress of Molecular & Cell Biology(招待講演)
    • Place of Presentation
      Beijing, China
    • Data Source
      KAKENHI-PROJECT-23590546
  • [Presentation] キメラタンパク質を用いたAPOBEC1の抗HIV-1活性に関する責任部位の機能解析2011

    • Author(s)
      池田輝政、小糸 厚
    • Organizer
      第25回日本エイズ学会学術集会総会
    • Place of Presentation
      ハイアット リージェンシー東京
    • Data Source
      KAKENHI-PROJECT-23590546
  • 1.  NAKAUCHI Hiromitsu (40175485)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 2.  澤田 新一郎
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 3.  中村 幸夫 (60231479)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  廣近 玲 (90260223)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  TOKUNAGA Kenzo
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 6.  IKEDA Terumasa
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 7.  阪口 薫雄
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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