Ohkubo Takeshi 大久保武

… Alternative Names

OHKUBO Takeshi 大久保武

大久保武オオクボタケシ

Less

Researcher Number	70233070
Other IDs
Affiliation (Current)	2025: 茨城大学, 応用生物学野, 教授 2025: 東京農工大学, (連合)農学研究科(研究院), 教授
Affiliation (based on the past Project Information) *help	2025: 茨城大学, 応用生物学野, 教授 2016 – 2023: 茨城大学, 農学部, 教授 2012 – 2014: 茨城大学, 農学部, 教授 2007: Kagawa University, Faculty of Agriculture, Associate Professor 2006: Kagawa University, Faculty of Agriculture, Associate Professor, 農学部, 助教授 … More 2005: 香川県, 農学部, 助教授 2002 – 2003: 香川大学, 農学部, 助教授 1999 – 2000: 三重大学, 遺伝子実験施設, 助手 1997: Mie University Center of Mol.Biol.and Genetics Assistant Professor, 遺伝子実験施設, 助手 1995: 三重大学, 遺伝子実験施設, 助手 Less
Review Section/Research Field	Principal Investigator Basic Section 42010:Animal production science-related / Applied animal science / Basic Section 42010:Animal production science-related / Animal production science / Basic veterinary science/Basic zootechnical science / Zootechnical science/Grassland science Except Principal Investigator Zootechnical science/Grassland science / Applied animal science
Keywords	Principal Investigator レプチン / ニワトリ / 摂食 / 視床下部 / 下垂体 / バイオアッセイ / 情報伝達 / ブロイラー / 卵胞発育 / NPW … More / 抱卵 / C-reactive protein / CPR / エネルギー代謝 / CRP / シグナル伝達 / 家禽 / 卵巣 / signal transduction / Bioassay / leptin / chicken / 細胞内情報伝達 / クローニング / 鳥類 / 比較ゲノミクス / オレキシン / レプチン受溶体 / Growth Horwone / Prolactin / Pit-1 / Chicken … More Except Principal Investigator hypothalamus / pituitary / prolactin receptor / mRNA / chicken / incubation behavior / prolactin / Central nervous system / Peptide hormone / RNA interference / Feeding behavior / Chicks / 中枢 / ペプチドホルモン / RNA干渉 / 摂食行動 / ニワトリヒナ / recombinant PRL / PRL-Rc / cyclic AMP / GRF / VIP / GHmRNA / PRLmRNA / antisense / GnRH / VIP Receptor / PRL mRNA Less

ニワトリ初期胚の性腺の分化・発達におけるレプチンの役割Principal Investigator
- Principal Investigator
  
  大久保武
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42010:Animal production science-related
- Research Institution
  Ibaraki University
Ovarian dysfunction normalization in broiler breeder chicken through leptin system manipulationPrincipal Investigator
- Principal Investigator
  
  大久保武
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Review Section
  
  Basic Section 42010:Animal production science-related
- Research Institution
  Ibaraki University
Involvement of feeding factors in developing hypothalamus-pituitary system.Principal Investigator
- Principal Investigator
  
  大久保武
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42010:Animal production science-related
- Research Institution
  Ibaraki University
Analysis of the adaptation for the spontaneous low-energy state in chickens during incubation behaviorPrincipal Investigator
- Principal Investigator
  
  Ohkubo Takeshi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42010:Animal production science-related
- Research Institution
  Ibaraki University
Study on the regulation of pituitary function in chicken by adipokine, leptinPrincipal Investigator
- Principal Investigator
  
  Ohkubo Takeshi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Animal production science
- Research Institution
  Ibaraki University
Screening of avian leptin using real-time imaging assay for leptinPrincipal Investigator
- Principal Investigator
  
  OHKUBO Takeshi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Zootechnical science/Grassland science
- Research Institution
  Ibaraki University
Development of in vitro bioassay for avian leptinPrincipal Investigator
- Principal Investigator
  
  OHKUBO Takeshi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Basic veterinary science/Basic zootechnical science
- Research Institution
  Kagawa University
Feeding behavior and growth in Chicks treated RNA interference
- Principal Investigator
  
  BUNGO Takashi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Zootechnical science/Grassland science
- Research Institution
  HIROSHIMA UNIVERSITY
家禽の摂食、エネルギー代謝調節因子の脳内制御機構の解明Principal Investigator
- Principal Investigator
  
  大久保武
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Applied animal science
- Research Institution
  Kagawa University
鳥類摂食関連遺伝子のクローニング及び中枢神経系での制御機構に関する研究Principal Investigator
- Principal Investigator
  
  大久保武
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Applied animal science
- Research Institution
  Mie University
ニワトリ下垂体特異的転写因子Pit-1遺伝子の構造と発現調節機構に関する研究Principal Investigator
- Principal Investigator
  
  大久保武
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Applied animal science
- Research Institution
  Mie University
Molecular studies on incubation behavior and the application
- Principal Investigator
  
  SHIMADA Kiyoshi
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Field
  
  Applied animal science
- Research Institution
  Nagoya University

All 2024 2023 2022 2021 2020 2019 2018 2017 2014 2013 2007 2006 Other

All Journal Article Presentation

[Journal Article] Impact of In Ovo Leptin Injection and Dietary Protein Levels on Ovarian Growth Markers and Early Folliculogenesis in Post-Hatch Chicks (Gallus gallus domesticus)2024
- Author(s)
  Ahmadi Sadequllah、Nemoto Yuta、Ohkubo Takeshi
- Journal Title
  
  Biology
  
  Volume: 13 Issue: 2 Pages: 69-69
- DOI
  10.3390/biology13020069
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23KF0009, KAKENHI-PROJECT-22K05967
[Journal Article] Orexin system is expressed in avian liver and regulates hepatic lipogenesis via ERK1/2 activation2020
- Author(s)
  Greene E. S.、Zampiga M.、Sirri F.、Ohkubo T.、Dridi S.
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 19191-19191
- DOI
  10.1038/s41598-020-76329-2
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06350
[Journal Article] Identification of hypothalamic genes in associating with food intake during incubation behavior in domestic chicken2019
- Author(s)
  Takeda Misa、Ohkubo Takeshi
- Journal Title
  
  Animal Science Journal
  
  Volume: 90 Issue: 9 Pages: 1293-1302
- DOI
  10.1111/asj.13261
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K06350
[Journal Article] Determination of Polymorphisms in Pituitary Genes of the Native Afghani Naked Neck Chicken2019
- Author(s)
  Ahmadi Sadequllah、Takeda Misa、Ohkubo Takeshi
- Journal Title
  
  J. Poult. Sci.
  
  Volume: 56 Issue: 4 Pages: 253-261
- DOI
  10.2141/jpsa.0180087
- NAID
  130007733294
- ISSN
  1346-7395, 1349-0486
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06350
[Journal Article] Determination of Polymorphisms in Pituitary Genes of the Native Afghani Naked Neck Chicken2019
- Author(s)
  Ahmadi S, Takeda M, Ohkubo T
- Journal Title
  
  Journal of Poultry Science
  
  Volume: 印刷中
- NAID
  130007733294
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07983
[Journal Article] Gene expression profiling in embryonic chicken ovary during asymmetric development.2018
- Author(s)
  Shaikat AH, Namekawa S, Ahmadi S, Takeda M and Ohkubo T
- Journal Title
  
  Animal Science Journal
  
  Volume: 89 Issue: 4 Pages: 688-694
- DOI
  10.1111/asj.12979
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K07983
[Journal Article] AMP-activated protein kinase mediates the effect of leptin on avian autophagy in a tissue-specific manner2018
- Author(s)
  Piekarski A, Nagarajan G, Ishola P, Flees J, Greene E, Kuenzel W, Ohkubo T, Helena Maier H, Bottje W, Cline M, Dridi S
- Journal Title
  
  Frontiers in Physiology
  
  Volume: 印刷中 Pages: 541-541
- DOI
  10.3389/fphys.2018.00541
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07983
[Journal Article] Discovery of the elusive leptin in birds: identification of several 'missing links' in the evolution of leptin and its receptor.2014
- Author(s)
  Prokop JW, Schmidt C, Gasper D, Duff RJ, Milsted A, Ohkubo T, Ball HC, Shawkey MD, Mays HL Jr, Cogburn LA, Londraville RL.
- Journal Title
  
  PLoS One
  
  Volume: 9 Issue: 3 Pages: e92751-e92751
- DOI
  10.1371/journal.pone.0092751
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24580386
[Journal Article] Recent Progress in Avian Leptin Research2014
- Author(s)
  Ohkubo T
- Journal Title
  
  J. Poult. Sci.
  
  Volume: 51 Issue: 4 Pages: 343-351
- DOI
  10.2141/jpsa.0130236
- NAID
  130004446441
- ISSN
  1346-7395, 1349-0486
- Language
  English
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24580386
[Journal Article] Recent progress in avian leptin research.2014
- Author(s)
  Ohkubo T
- Journal Title
  
  Journal of Poultry Science
  
  Volume: 51
- NAID
  130004446441
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24580386
[Journal Article] Avian blood induced intranuclear translocation of STAT3 via the chicken leptin receptor2014
- Author(s)
  Ohkubo T, Hirota K, Murase D, Hiromi Adachi H, Nozawa-Takeda T, Sugita S
- Journal Title
  
  Comparative Biochemistry and Physiology Part B
  
  Volume: 174 Pages: 9-14
- DOI
  10.1016/j.cbpb.2014.05.001
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24580386
[Journal Article] Inhibitory mechanism of signal transduction through chicken leptin receptor by suppressor of cytokine signaling-3 (SOCS3).2013
- Author(s)
  Adachi, H., Murase, D. and Ohkubo, T.
- Journal Title
  
  Journal of Poultry Science
  
  Volume: 50
- NAID
  10031189334
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24580386
[Journal Article] Structure and tissue distribution of cholecystokinin-1 receptor in chicken2007
- Author(s)
  Ohkubo, T.
- Journal Title
  
  Journal of Poultry Science 44
  
  Pages: 98-104
- NAID
  10018485748
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18580290
[Journal Article] Existence of leptin receptor protein in chicken tissues : isolation of a monoclonal antibody against chicken leptin receptor2007
- Author(s)
  T. Ohkubo
- Journal Title
  
  General and Comparative Endocrinology 151
  
  Pages: 269-273
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18580290
[Journal Article] Existence of leptin receptor protein in chicken tissues:isolation of a monoclonal antibody against chicken letin recetor2007
- Author(s)
  T. Ohkubo
- Journal Title
  
  General and Comparative Endocrinology 151
  
  Pages: 269-273
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18580290
[Journal Article] Existence of leptin receptor protein in chicken tissues:isolation of a monoclonal antibody against chicken leptin receptor2007
- Author(s)
  T. Ohkubo
- Journal Title
  
  General and Comparative Endocrinology 151
  
  Pages: 269-273
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18580290
[Journal Article] Structure and tissue distribution of cholecystokinin-1 receptor in chicken2007
- Author(s)
  Ohkubo, T
- Journal Title
  
  Journal of Poultry Science 44
  
  Pages: 98-104
- NAID
  10018485748
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18580290
[Journal Article] Existence of leptin receptor protein in chicken tissues : isolation of a monoclonal antibody against chicken leptin receptor.2007
- Author(s)
  T.Ohkubo
- Journal Title
  
  General and Comparative Endocrinology (in press)
- Data Source
  KAKENHI-PROJECT-18580290
[Presentation] Effect on Notch signaling genes expression during primordial follicle activation by leptin and IGF-1 in juvenile chicks2023
- Author(s)
  アハマディ・サデクラー, 神戸望, 大久保武
- Organizer
  日本家禽学会２０２３年度春季大会
- Data Source
  KAKENHI-PROJECT-22K05967
[Presentation] Leptin stimulates ovarian insulin-like growth factor-1 mRNA expression and promotes primordial follicle development in juvenile chicks2022
- Author(s)
  Sadequllah Ahmadi and Takeshi Ohkubo
- Organizer
  日本家禽学会2022年度春季大会
- Data Source
  KAKENHI-PROJECT-19K06350
[Presentation] ニワトリ後期胚の発生におけるNPW及びNPBWR2発現変動と生理機能変化の可能性2021
- Author(s)
  有馬明莉、曳地結衣、神作宜男、大久保武
- Organizer
  日本家禽学会2021年度春季大会
- Data Source
  KAKENHI-PROJECT-19K06350
[Presentation] ニワトリ発生胚下垂体に対するVIPアンタゴニストのPRL分泌抑制作用2021
- Author(s)
  神作宜男、大久保武、河上真一
- Organizer
  日本家禽学会2021年度春季大会
- Data Source
  KAKENHI-PROJECT-19K06350
[Presentation] トランスサイレチン及びプロラクチン放出ペプチド mRNA 発現に対する短期絶食の影響2018
- Author(s)
  武田未紗、大久保武
- Organizer
  日本家禽学会２０１８年度秋季大会
- Data Source
  KAKENHI-PROJECT-16K07983
[Presentation] Intracerebroventricular administration of leptin induces hepatic autophagy in chickens through AMPK pathway2018
- Author(s)
  Greene E, Flees J, Bottje W, Ohkubo T, Maier H, Cline M, Dridi S
- Organizer
  Poultry Science Association 107th Annual Meeting
- Data Source
  KAKENHI-PROJECT-16K07983
[Presentation] Neuroendocrine regulation of avian hypothalamic autophagy by leptin.2018
- Author(s)
  Flees J, Greene E, Kuenzel W, Bottje W, Ohkubo T, Maier H, Cline M, and Dridi S
- Organizer
  Poultry Science Association 107th Annual Meeting
- Data Source
  KAKENHI-PROJECT-16K07983
[Presentation] アフガニスタン在来の Naked Neck のおけるプロラクチン及び Pit-1 遺伝子の遺伝子多型2017
- Author(s)
  サデクラーアハマディ、大久保武
- Organizer
  日本家禽学会2017年度春季大会
- Place of Presentation
  神戸大学
- Data Source
  KAKENHI-PROJECT-16K07983
[Presentation] Does leptin have a role in asymmetrical development of chicken ovary2017
- Author(s)
  Shaikat Amir, Namekawa Shoko, Ahmadi Sadequllah, Takeda Misa, Ohkubo takeshi
- Organizer
  日本畜産学会第122回大会
- Place of Presentation
  神戸大学
- Year and Date
  2017-03-28
- Data Source
  KAKENHI-PROJECT-16K07983
[Presentation] レプチンはニワトリヒナの卵巣のレプチン受容体、FSH 受容体、アロマターゼ及びアポトーシスマーカーの発現を制御する。2017
- Author(s)
  Amir Hossan Shaikat、大久保武
- Organizer
  日本家禽学会2017年度春季大会
- Place of Presentation
  神戸大学
- Data Source
  KAKENHI-PROJECT-16K07983
[Presentation] ウコッケイ視床下部における抱卵行動関連遺伝子の発現2017
- Author(s)
  武田未紗、大久保武
- Organizer
  日本家禽学会2017年度春季大会
- Place of Presentation
  神戸大学
- Data Source
  KAKENHI-PROJECT-16K07983
[Presentation] 抱卵行動がニワトリ視床下部の摂食関連遺伝子の発現に及ぼす影響2014
- Author(s)
  児玉孝弘、大貫瑠美、大久保武
- Organizer
  日本家禽学会
- Place of Presentation
  筑波大学
- Data Source
  KAKENHI-PROJECT-24580386
[Presentation] 鳥類血清中のレプチン様活性の検出2013
- Author(s)
  村瀬大輔、廣田佳菜子、安達洋泉、竹田努、杉田昭栄、大久保武
- Organizer
  日本家禽学会
- Place of Presentation
  安田女子大学
- Data Source
  KAKENHI-PROJECT-24580386
[Presentation] Role of transactivation domain of Pit-1 is different in the transcriptional regulation of GH gene by leptin in chicken and mouse.2013
- Author(s)
  Murase T, Ogawa K, Ohkubo T
- Organizer
  17th International congress of Comparative Endocrinology
- Place of Presentation
  Barcelona, Spain
- Data Source
  KAKENHI-PROJECT-24580386
[Presentation] Molecular mechanism of food intake in poultry2006
- Author(s)
  Takeshi, Ohkubo
- Organizer
  Meeting of Metabolism and Nutrition
- Place of Presentation
  Sendai
- Year and Date
  2006-10-01
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18580290
[Presentation] Changes in appetite-associated genes in the chicken hypothalamus during incubation behavior
- Author(s)
  Ohkubo T, Kodama T, Ohnuki R
- Organizer
  10 Asia Pacific Poultry Congress
- Place of Presentation
  Jeju Korea
- Year and Date
  2014-10-19 – 2014-10-23
- Data Source
  KAKENHI-PROJECT-24580386

1. SHIMADA Kiyoshi (40065579)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. SAITO Noboru (40211924)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. KUWAYAMA Takehito (40215124)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. BUNGO Takashi (40325361)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 河本馨 (30011894)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. KATO Yukio

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. NAMEKAWA Shoko

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
8. SHAIKAT Amir H.

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
9. M.EL Halawan

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. DAVID Zadowo

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. PROUDMAN Jo

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. ZADWORNY Da

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. SHARP Peter

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. AHMADI SADEQULLAH

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results

Ohkubo Takeshi 大久保 武

OHKUBO Takeshi 大久保 武

大久保 武 オオクボ タケシ

Research Projects

Research Products

Co-Researchers

ニワトリ初期胚の性腺の分化・発達におけるレプチンの役割Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Ovarian dysfunction normalization in broiler breeder chicken through leptin system manipulationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Involvement of feeding factors in developing hypothalamus-pituitary system.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of the adaptation for the spontaneous low-energy state in chickens during incubation behaviorPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Study on the regulation of pituitary function in chicken by adipokine, leptinPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Screening of avian leptin using real-time imaging assay for leptinPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of in vitro bioassay for avian leptinPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Feeding behavior and growth in Chicks treated RNA interference

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

家禽の摂食、エネルギー代謝調節因子の脳内制御機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

鳥類摂食関連遺伝子のクローニング及び中枢神経系での制御機構に関する研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ニワトリ下垂体特異的転写因子Pit-1遺伝子の構造と発現調節機構に関する研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular studies on incubation behavior and the application

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Impact of In Ovo Leptin Injection and Dietary Protein Levels on Ovarian Growth Markers and Early Folliculogenesis in Post-Hatch Chicks (Gallus gallus domesticus)2024

Author(s)

Ohkubo Takeshi 大久保武

OHKUBO Takeshi 大久保武

大久保武オオクボタケシ