AKIMARU Hiroshi 秋丸裕司

… Alternative Names

秋丸裕司アキマルヒロシ

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Researcher Number	70241247
Affiliation (based on the past Project Information) *help	2014: 公益財団法人先端医療振興財団, その他部局等, 研究員 2013: 公益財団法人先端医療振興財団, 先端医療センター研究所再生医療研究部血管再生研究グループ, 客員研究員 2003: 独立行政法人理化学研究所, 分子遺伝学研究室, 先任研究員 1999 – 2002: Laboratory of Moleular and Genetics, Senior Research Schientist, 分子遺伝学研究室, 先任研究員 1997 – 1998: 理化学研究所, 分子遺伝学研究室, 研究員 1992 – 1994: 理化学研究所, 分子遺伝学研究室, 研究員
Review Section/Research Field	Principal Investigator Biological Sciences / Developmental biology / Regenerative medicine Except Principal Investigator General medical chemistry
Keywords	Principal Investigator ショウジョウバエ / 形態形成 / RNAi / JNK / モザイク解析 / Hedgehog / dmi-2 / dmyb / p38 / ATF-2 … More / Hedghog / 翅成虫原基 / 分子遺伝学 / 転写因子 / Cubitus interruptus / mosaic analysis / cell cycle / eye imaginal disc / transcription factor / Drosophila / 複眼 / Mi-2 / Myb / 細胞周期 / 複眼成虫原基 / single cell qPCR / シングルセルqPCR / EPC / 血管内皮前駆細胞 / ヒトiPS / osmotic stress / apoptosis / 蛋白質分解 / cubitus interruptus / multi vesicular body / ubiquitination / 免疫電顕 / endosome / 成虫原基 / MVB / lysosome / ユビキチン / Hedgehoge / MEKK / dsRNA / dATF-2 / SAPK / ユビキチネーション / タンパク質分解 / Ci / CBP / Moonrat / co-activator / CREB-binding protein / 発生 / CREB binding protein … More Except Principal Investigator CBP / ショウジョウバエ / Ski / コアクティベーター / Myb / Histone acetylation / Co-repressor / C-activator / ヒストンアセチル化 / コリプレッサー / mouse mutant / Drosophila mutant / coactivator / transcriptional mediators / 形態形成 / 転写制御 / 仲介因子 / コアクティベータ- / マウス変異体 / ショウジョウバエ変異体 / 転写仲介因子 / 劣性致死突然変異体 / 変異体 / 発生 / 転写制御因子 Less

ヒトiPS 由来血管内皮前駆細胞の機能評価の構築Principal Investigator
- Principal Investigator
  
  秋丸裕司
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Regenerative medicine
- Research Institution
  Foundation for Biomedical Research and Innovation
アポトーシスにおけるショウジョウバエJNK/p38とATF-2の遺伝学的機能解析Principal Investigator
- Principal Investigator
  
  秋丸裕司
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The Institute of Physical and Chemical Research
RNAiを用いたショウジョウバエATF-2のアポトーシスへの機能解析Principal Investigator
- Principal Investigator
  
  秋丸裕司
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The Institute of Physical and Chemical Research
ショウジョウバエHh/Ci伝達系に関与する遺伝子の単離と機能解析Principal Investigator
- Principal Investigator
  
  秋丸裕司
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The Institute of Physical and Chemical Research
ショウジョウバエHh/Ci伝達系に関与する遺伝子の単離と機能解析Principal Investigator
- Principal Investigator
  
  秋丸裕司
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  The Institute of Physical and Chemical Research
RNAiを用いたショウジョウバエATF-2のアポートシスへの機能解析Principal Investigator
- Principal Investigator
  
  秋丸裕司
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  The Institute of Physical and Chemical Research
ショウジョウバエHh/dCBP/Ci伝達系に関与する遺伝子の単離同定Principal Investigator
- Principal Investigator
  
  秋丸裕司
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  The Institute of Physical and Chemical Research
ショウジョウバエHh/dCBP/Ci伝達系に関与する遺伝子の単離同定Principal Investigator
- Principal Investigator
  
  秋丸裕司
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  The Institute of Physical and Chemical Research
Research on Gene Expression Network via histone acetylation
- Principal Investigator
  
  ISHII Shunsuke
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  General medical chemistry
- Research Institution
  The Institute of Physical and Chemical Research (RIKEN)
ショウジョウバエHh/dCBP/Ci伝達系に関与する遺伝子の単離同定Principal Investigator
- Principal Investigator
  
  秋丸裕司
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  The Institute of Physical and Chemical Research
Functional analysis of the D-myb gene in DrosophilaPrincipal Investigator
- Principal Investigator
  
  AKIMARU Hiroshi
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Developmental biology
- Research Institution
  The Institute of Physical and Chemical Research, RIKEN
Research on Gene Expression Network via Coactivator CBP
- Principal Investigator
  
  ISHII Shunsuke
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  The Institute of Physical and Chemical Research (RIKEN)
ショウジョウバエMyb,CRE結合蛋白質の遺伝学的解析
- Principal Investigator
  
  石井俊輔
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The Institute of Physical and Chemical Research
細胞増殖を制御する転写因子の遺伝学的解析
- Principal Investigator
  
  石井俊輔
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The Institute of Physical and Chemical Research
細胞増殖を制御する転写因子の遺伝学的解析
- Principal Investigator
  
  ISHII Shunsuke
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The Institute of Physical and Chemical Research

All 2015 2014 2013

All Journal Article Book

[Book] 図説分子病態学　改訂5版(6．細胞の増殖・分化と再生医学)2014
- Author(s)
  秋丸裕司　浅原孝之(一瀬白帝編著)
- Total Pages
  408
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-25505009
[Journal Article] SDF-1/CXCR4 Axis in Tie2-lineage Cells Including Endothelial Progenitor Cells Contributes to Bone Fracture Healing.2015
- Author(s)
  Kawakami Y, Ii M, Matsumoto T, Kuroda R, Kuroda T, Kwon SM, Kawamoto A, Akimaru H, Mifune Y, Shoji T, Fukui T, Kurosaka M, Asahara T.
- Journal Title
  
  J Bone Miner Res.
  
  Volume: 30(1) Issue: 1 Pages: 95-105
- DOI
  10.1002/jbmr.2318
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25505009, KAKENHI-PROJECT-25462331
[Journal Article] Sonic Hedgehog signaling regulates vascular differentiation and function in human CD34 positive cells: vasculogenic CD34(+) cells with Sonic Hedgehog.2015
- Author(s)
  Kanaya K, Masaaki I, Okazaki T, Nakamura T, Horii-Komatsu M, Alev C, Akimaru H, Kawamoto A, Akashi H, Tanaka H, Asahi M, Asahara T.
- Journal Title
  
  Stem Cell Res
  
  Volume: 14(2) Issue: 2 Pages: 165-76
- DOI
  10.1016/j.scr.2015.01.003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25460397, KAKENHI-PROJECT-25505009
[Journal Article] Dextran induces differentiation of circulating endothelial progenitor cells.2014
- Author(s)
  S. Obi, H. Masuda, H. Akimaru, T. Shizuno, K. Yamamoto, J. Ando, and T. Asahara
- Journal Title
  
  Physiol. Rep.
  
  Volume: 2 Issue: 3 Pages: e00261-e00261
- DOI
  10.1002/phy2.261
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25282128, KAKENHI-PROJECT-25461091, KAKENHI-PROJECT-25505009, KAKENHI-PROJECT-26242043
[Journal Article] Vasculogenic conditioning of peripheral blood mononuclear cells promotes endothelial progenitor cell expansion and phenotype transition of anti-inflammatory macrophage and T lymphocyte to cells with regenerative potential.2014
- Author(s)
  H. Masuda, R. Tanaka, S. Fujimura, M. Ishikawa, H. Akimaru, T. Shizuno, A. Sato, Y. Okada, Y. Iida, J. Itoh, Y. Itoh, H. Kamiguchi, A. Kawamoto, T. Asahara.
- Journal Title
  
  J Am Heart Assoc.
  
  Volume: 3 Issue: 3
- DOI
  10.1161/jaha.113.000743
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25461091, KAKENHI-PROJECT-25505009, KAKENHI-PROJECT-26461320
[Journal Article] Superior Potential of CD34-Positive Cells Compared to Total Mononuclear Cells for Healing of Nonunion Following Bone Fracture.2014
- Author(s)
  Fukui T, Mifune Y, Matsumoto T, Shoji T, Kawakami Y, Kawamoto A, Ii M, Akimaru H, Kuroda T, Horii M, Yokoyama A, Alev C, Kuroda R, Kurosaka M, Asahara T.
- Journal Title
  
  Cell Transplant
  
  Volume: May 2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25505009
[Journal Article] Human cardiac stem cells with reduced notch signaling show enhanced therapeutic potential in a rat acute infarction model.2013
- Author(s)
  Matsuda T, Miyagawa S, Fukushima S, Kitagawa-Sakakida S, Akimaru H, Horii-Komatsu M, Kawamoto A, Saito A, Asahara T, Sawa Y.
- Journal Title
  
  Circ J
  
  Volume: 78(1) Pages: 222-231
- NAID
  130003382177
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25505009
[Journal Article] A small interfering RNA targeting Lnk accelerates bone fracture healing with early neovascularization2013
- Author(s)
  Kawakami Y, Ii M, Matsumoto T, Kawamoto A, Kuroda R, Akimaru H, Mifune Y, Shoji T, Fukui T, Asahi M, Kurosaka M, Asahara T.
- Journal Title
  
  Laboratory Investigation
  
  Volume: 93 Issue: 9 Pages: 1036-1053
- DOI
  10.1038/labinvest.2013.93
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460397, KAKENHI-PROJECT-25462331, KAKENHI-PROJECT-25505009

1. ISHII Shunsuke (00124785)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
2. MAEKAWA Toshio (90201764)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 浅原孝之 (20246200)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
4. 川本篤彦 (00275330)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
5. ASAHI Michio

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
6. Ii Masaaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
7. MASUDA Haruchika

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 安藤譲二

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 山本希美子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

AKIMARU Hiroshi 秋丸 裕司

秋丸 裕司 アキマル ヒロシ

Research Projects

Research Products

Co-Researchers

ヒトiPS 由来血管内皮前駆細胞の機能評価の構築Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

アポトーシスにおけるショウジョウバエJNK/p38とATF-2の遺伝学的機能解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

RNAiを用いたショウジョウバエATF-2のアポトーシスへの機能解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ショウジョウバエHh/Ci伝達系に関与する遺伝子の単離と機能解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ショウジョウバエHh/Ci伝達系に関与する遺伝子の単離と機能解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

RNAiを用いたショウジョウバエATF-2のアポートシスへの機能解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ショウジョウバエHh/dCBP/Ci伝達系に関与する遺伝子の単離同定Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

ショウジョウバエHh/dCBP/Ci伝達系に関与する遺伝子の単離同定Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Research on Gene Expression Network via histone acetylation

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ショウジョウバエHh/dCBP/Ci伝達系に関与する遺伝子の単離同定Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Functional analysis of the D-myb gene in DrosophilaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Research on Gene Expression Network via Coactivator CBP

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ショウジョウバエMyb,CRE結合蛋白質の遺伝学的解析

Principal Investigator

Project Period (FY)

Research Category

Research Institution

細胞増殖を制御する転写因子の遺伝学的解析

AKIMARU Hiroshi 秋丸裕司

秋丸裕司アキマルヒロシ

[Book] 図説分子病態学　改訂5版(6．細胞の増殖・分化と再生医学)2014