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HASHIMOTO Fumio  橋本 文雄

ORCIDConnect your ORCID iD *help
Researcher Number 70244142
Other IDs
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Affiliation (Current) 2025: 鹿児島大学, 農水産獣医学域農学系, 教授
Affiliation (based on the past Project Information) *help 2015 – 2021: 鹿児島大学, 農水産獣医学域農学系, 教授
2012 – 2014: 鹿児島大学, 農学部, 教授
2011: 鹿児島大学, 農学部, 准教授
2007 – 2008: 鹿児島大学, 農学部, 准教授
2006: 鹿児島大学, 農学部, 助教授
1997 – 1998: 鹿児島大学, 農学部, 助教授
1996: 熊本大学, 薬学部, 助手
Review Section/Research Field
Principal Investigator
Horticultural science / Horticulture/Landscape architecture / Chemical pharmacy
Except Principal Investigator
Food science / Basic Section 39030:Horticultural science-related / Horticultural science / 医薬分子機能学
Keywords
Principal Investigator
遺伝育種 / 遺伝生化学 / アントシアニン / 複対立遺伝 / トルコギキョウ / チューリップ / 化学分類 / 園芸利用 / diosgenin / solasodine … More / steroidal alkaloid / HMG CoA reductase / Solanum viarum / 26-aminocholesterol … More
Except Principal Investigator
アントシアニン / 花色 / トルコギキョウ / 細胞癌化抑制能 / 遺伝子組換え / コピグメンテーション / フラボノール / グルコシル化 / 遺伝学 / 植物 / 遺伝子 / 育種学 / 園芸学 / 花色育種 / 花卉 / 分子育種 / F3H / トランスポゾンディスプレイ / 突然変異 / 斑入り / 突然変異育種 / トランスポゾン / Ursolic acid / Oleanolic acid / Betulinic acid / Triterpenoids / Anti-HIV / ベツリン酸 / ウルソール酸 / オレアノール酸 / ぺツリン酸 / トリテルペノイド / 抗AIDS作用 / 結合解析 / MAP キナーゼ / 炎症抑制能 / 結合モデル構築 / 直接結合能 / 親和力 / MAPキナーゼ / 細胞標的分子 / 食品機能性 / 分子作用機構 / NF-kB / 細胞シグナル伝達 / 食品分子作用機構 / MEK1 / 分子標的 / 分子機構 / 標的分子 / シグナル伝達 / 細胞がん化 Less
  • Research Projects

    (8 results)
  • Research Products

    (25 results)
  • Co-Researchers

    (11 People)
  •  Flower color modification through interaction between B-ring glycosylated delphinidins and flavonols in Eustoma grandiflorum

    • Principal Investigator
      Noda Naonobu
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 39030:Horticultural science-related
    • Research Institution
      National Agriculture and Food Research Organization
  •  Analysis and utilization of transposon isolated from a variegated flower line in Eustoma grandiflorumm

    • Principal Investigator
      Shimizu Keiichi
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Horticultural science
    • Research Institution
      Kagoshima University
  •  Breeding method for creating new types of flower colors of EustomaPrincipal Investigator

    • Principal Investigator
      Hashimoto Fumio
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Horticultural science
    • Research Institution
      Kagoshima University
  •  Chemosystematic of Tulips based on tepal anthocyanins as phenetic markersPrincipal Investigator

    • Principal Investigator
      HASHIMOTO Fumio
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Horticulture/Landscape architecture
    • Research Institution
      Kagoshima University
  •  Clarification of the molecular targets for bioactive anthocyanins: MAP kinase as direct targets

    • Principal Investigator
      HOU De-Xing
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Food science
    • Research Institution
      Kagoshima University
  •  Signaling pathways for the inhibition of cell transformation by anthocyanins

    • Principal Investigator
      HOU De-xing
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Food science
    • Research Institution
      Kagoshima University
  •  Colaborative Research on Anti-HIV Triterpenoids

    • Principal Investigator
      KASHIWADA Yoshiki
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Field
      医薬分子機能学
    • Research Institution
      Niigata College of Pharmacy
  •  新規抗脂血症用薬"26-aminocholesterol"合成法の開発Principal Investigator

    • Principal Investigator
      橋本 文雄
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Chemical pharmacy
    • Research Institution
      Kumamoto University

All 2017 2016 2015 2014 2013 2012 2011 2007

All Journal Article Presentation Patent

  • [Journal Article] Efficiency of Hand-thinning in Apple Cultivars with Varying Degrees of Fruit Abscission2015

    • Author(s)
      Yuka Takatori, Keiichi Shimizu, Jun Ogata, Hiroki Endo, Kanji Ishimaru, Shigehisa Okamoto, Fumio Hashimoto.
    • Journal Title

      The Horticulture Journal

      Volume: 84 Issue: 2 Pages: 99-105

    • DOI

      10.2503/hortj.CH-112

    • NAID

      130005066775

    • ISSN
      2189-0102, 2189-0110
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26450040
  • [Journal Article] 野生種トルコギキョウを起源とする二重咲き花形の遺伝様式2015

    • Author(s)
      髙取由佳, 櫟本裕太郎, 清水圭一, 橋本文雄
    • Journal Title

      園芸学研究

      Volume: 3

    • NAID

      130005117153

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26450040
  • [Journal Article] Anti-inflammatory effects and molecular mechanisms of loquat (Eriobotrya japonica) tea2014

    • Author(s)
      Zar PPK, Moroshita A, Hashimoto F, Sakao K, Fujii M, Wada K, Hou DX*
    • Journal Title

      J Functional Foods

      Volume: 6 Pages: 523-533

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23580176
  • [Journal Article] Anti-inflammatory effects and molecular mechanisms of loquat (Eriobotrya japonica) tea2014

    • Author(s)
      Zar PPK, Moroshita A, Hashimoto F, Sakao K, Fujii M, Wada K, Hou DX
    • Journal Title

      J. Functional Foods

      Volume: 6 Pages: 523-533

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23580176
  • [Journal Article] A genome-wide microarray highlights the anti-inflammatory genes targeted by oolong tea theasinensin A in macrophages2011

    • Author(s)
      Chen J, Qin S, Xiao J, Tanigawa S, Uto T, Hashimoto F, Fujii M and Hou DX
    • Journal Title

      Nutr. Cancer

      Volume: 63(7) Pages: 1064-1073

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23580176
  • [Journal Article] Green tea proanthocyanidins inhibit cyclooxygenase-2 expression in LPSactivated mouse macrophages : molecular mechanisms and structure-activity relationship2007

    • Author(s)
      Hou DX*, Masuzaki S, Hashimoto F, UtoT, Tanigawa S, Fujii M, Sakata Y
    • Journal Title

      Arch. Biochem. Biophys. 460(1)

      Pages: 67-74

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18580125
  • [Journal Article] Prodelphinidin B-4 3'-O-gallate, a tea polyphenol, is involved in the inhibition of COX-2 and iNOS via the downregulation of TAK1-NF-kappaB pathway.2007

    • Author(s)
      Hou DX, Luo D, Tanigawa S, Hashimoto F, Uto T, Masuzaki S, Fujii M, Sakata Y.
    • Journal Title

      Biochem Pharmacol. 74(5)

      Pages: 742-751

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18580125
  • [Journal Article] Prodelphinidin B-4 3'-O-gallate, a tea polyphenol, is involved in the inhibition of COX-2 and iNOS via the downregulation of TAK1-NF-kB pathway2007

    • Author(s)
      Hou DX*, Dong Luo, Tanikawa S, HashimotoF, Uto T, Masuzaki S, Fujii M, SakataY
    • Journal Title

      Biochem. Pyarm. 74

      Pages: 742-752

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18580125
  • [Journal Article] Green tea proanthocyanidins inhibit cyclooxygenase-2 expression in LPS-activated mouse macrophages : Molecular mechanisms and structure-activity relationship.2007

    • Author(s)
      Hou DX, MasuzakiS, Hashimoto F, Uto T, Tanigawa S, Fujii M, Sakata Y.
    • Journal Title

      Archives of Biochemistry and Biophysics 460

      Pages: 67-74

    • Data Source
      KAKENHI-PROJECT-18580125
  • [Patent] トルコギキョウの新品種作出方法2014

    • Inventor(s)
      橋本文雄、清水圭一、髙取由佳
    • Industrial Property Rights Holder
      国立大学法人鹿児島大学、株式会社鹿児島TLO
    • Industrial Property Rights Type
      特許
    • Filing Date
      2014-10-03
    • Acquisition Date
      2016-04-07
    • Overseas
    • Data Source
      KAKENHI-PROJECT-26450040
  • [Presentation] トルコギキョウの花弁の斑入りに関する研究2017

    • Author(s)
      江上大貴,小畑舞,針原彩乃,福山達也,髙取由佳,清水圭一,橋本文雄
    • Organizer
      植物色素研究会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K07601
  • [Presentation] 近年のトルコギキョウ品種にみられる新奇な花冠形質の遺伝について2017

    • Author(s)
      安永智希,加藤文俊,鮫島理沙,田代桃子,江上大貴,清水圭一,髙取由佳,草留大陸,橋本文雄
    • Organizer
      園芸学会
    • Data Source
      KAKENHI-PROJECT-16K07601
  • [Presentation] Anthocyanidin synthase (ANS) 遺伝子の多型が トルコギキョウ花弁のアントシアニン色素の蓄積に及ぼす影響2017

    • Author(s)
      髙取 由佳, 清水 圭一, 橋本 文雄
    • Organizer
      園芸学会
    • Data Source
      KAKENHI-PROJECT-16K07601
  • [Presentation] トルコギキョウにおける黄色花の遺伝様式2016

    • Author(s)
      髙取由佳・清水圭一・橋本文雄
    • Organizer
      園芸学会秋季大会、園芸学研究
    • Place of Presentation
      名城大学(愛知県名古屋市)
    • Data Source
      KAKENHI-PROJECT-26450040
  • [Presentation] 鹿児島大学における花き研究の概要2016

    • Author(s)
      橋本文雄
    • Organizer
      農業開発総合センター・花き部・花き試験成績検討会ならびに試験課題検討会
    • Place of Presentation
      農業開発総合センター(鹿児島県日置市)
    • Invited
    • Data Source
      KAKENHI-PROJECT-26450040
  • [Presentation] 野生種トルコギキョウを起源とする二重咲き花形の遺伝様式2015

    • Author(s)
      高取由佳, 櫟本裕太郎, 清水圭一, 橋本文雄.
    • Organizer
      園芸学会秋季大会, 園芸学研究
    • Place of Presentation
      徳島大学(徳島県徳島市常三島キャンパス)
    • Year and Date
      2015-09-27
    • Data Source
      KAKENHI-PROJECT-26450040
  • [Presentation] Chemical Taxonomy of Tulip Cultivars by Tepal Anthocyanins2014

    • Author(s)
      Fumio Hashimoto1, Masayoshi Nakayama, Toshiaki Tsuji, Osamu Urashima, Misae Taya-Kizu, Akiko Nagai, Keiichi Shimizu
    • Organizer
      The XXVII International Conference on Polyphenols
    • Place of Presentation
      Nagoya University, Japan
    • Data Source
      KAKENHI-PROJECT-23580047
  • [Presentation] Chemosystematics of Tulips by tepal anthocyanins as phenetic markers2014

    • Author(s)
      Fumio Hashimoto, Masayoshi Nakayama, et al.
    • Organizer
      International Conference on Polyphenols
    • Place of Presentation
      Nagoya
    • Year and Date
      2014-09-03
    • Data Source
      KAKENHI-PROJECT-23580047
  • [Presentation] Flavonoid 3',5'-hydroxylase (F3'5'H) 遺伝子の多型がトルコギキョウ花弁のアントシアニジン組成に及ぼす影響2014

    • Author(s)
      高取由佳, 米澤徹, 前島理奈, 清水圭一, 橋本文雄
    • Organizer
      園芸学会秋季大会
    • Place of Presentation
      佐賀大学(佐賀県、佐賀市)
    • Year and Date
      2014-09-28
    • Data Source
      KAKENHI-PROJECT-26450040
  • [Presentation] Phenetics of tulip cultivars based on tepal anthocyanins2013

    • Author(s)
      Hashimoto, F., Ju, X.T., Nakayama, M, et al.
    • Organizer
      The 7^<th> International Workshop on Anthocyanins
    • Place of Presentation
      Porto, Portugal
    • Year and Date
      2013-09-09
    • Data Source
      KAKENHI-PROJECT-23580047
  • [Presentation] Detection of a copigment to delphinidin 3-rutinoside responsible for deep-purple color of tulip flower by the cross-TLC method2013

    • Author(s)
      Nakayama, M., Hashimoto, F
    • Organizer
      The 7^<th> International Workshop on Anthocyanins
    • Place of Presentation
      Porto, Portugal
    • Year and Date
      2013-09-09
    • Data Source
      KAKENHI-PROJECT-23580047
  • [Presentation] Detection of a copigment to delphinidin 3-rutinoside responsible for deep-purple color of tulip flower by the cross-TLC method2013

    • Author(s)
      Nakayama, M., Hashimoto, F.
    • Organizer
      The 7th International Workshop on Anthocyanins
    • Place of Presentation
      Porto University, Portugal
    • Data Source
      KAKENHI-PROJECT-23580047
  • [Presentation] Phenetics of tulip cultivars based on tepal anthocyanins2013

    • Author(s)
      Hashimoto, F., Ju, X.T., Nakayama, M., Kurashige, Y., Tsuji, T., Urashima, O, Taya-Kizu, M., Nagai, A., Shimizu, K.
    • Organizer
      The 7th International Workshop on Anthocyanins
    • Place of Presentation
      Porto University, Portugal
    • Data Source
      KAKENHI-PROJECT-23580047
  • [Presentation] Molecular basis for flavonoids: from gene expression profiling to molecule targeting2012

    • Author(s)
      Hou DX*, Tanigawa S, Chen JH, Qin S You SX, Kumamoto T, Hashimoto F, He X, He JH
    • Organizer
      13th Congress of the International Society for Ethnopharmacology
    • Place of Presentation
      Graz, Austria
    • Invited
    • Data Source
      KAKENHI-PROJECT-23580176
  • [Presentation] Molecular basis for flavonoids : from gene expression profiling to molecule targeting2012

    • Author(s)
      Hou DX, Tanigawa S, Chen JH, Qin S You SX, Kumamoto T, Hashimoto F, He X, He JH.
    • Organizer
      13th Congress of the International Society for Ethnopharmacology
    • Place of Presentation
      Graz, Austria
    • Data Source
      KAKENHI-PROJECT-23580176
  • 1.  HOU De-xing (90305160)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 9 results
  • 2.  Shimizu Keiichi (30305164)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 3.  FUJII Makoto (70041655)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 4.  NAKAYAMA Masayoshi (40237475)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 5.  KASHIWADA Yoshiki (30169429)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  NATAO Tsuneatsu (90180455)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  OKABE Hikaru (10078678)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  Noda Naonobu (10455313)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  李 國雄
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  LEE Kuo-Hsiung
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  季 國雄
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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