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FUKUISHI NobuyukiNobuyuki  福石 信之

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… Alternative Names

福石 信之  フクイシ ノブユキ

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Researcher Number 70248326
Other IDs
Affiliation (Current) 2025: 金城学院大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help 2017 – 2022: 金城学院大学, 薬学部, 教授
Review Section/Research Field
Except Principal Investigator
Drug development chemistry
Keywords
Except Principal Investigator
ラクタム剤 / 薬学 / 蛍光検出剤 / X線結晶構造解析 / βーラクタム剤 / 薬剤耐性菌 / メタローβーラクタマーゼ / βーラクタム / 抗生物質 / βーラクタマーゼ … More / 亜鉛酵素 / 細菌感染症 / ストップトフロー法 / 加水分解酵素 / β-ラクタム剤 / 金属酵素 / メタロ-β-ラクタマーゼ / 薬剤耐性 / 蛍光剤 / 阻害剤 / β-タクタム剤 / 感染症 Less
  • Research Projects

    (1 results)
  • Research Products

    (2 results)
  • Co-Researchers

    (2 People)
  •  Synthesis of inhibitors and fluorescence reagents for metallo-beta-lactamases

    • Principal Investigator
      Kurosaki Hiromasa
    • Project Period (FY)
      2017 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Drug development chemistry
    • Research Institution
      Kinjo Gakuin University

All 2022 2021

All Journal Article

  • [Journal Article] Difference in the Inhibitory Effect of Thiol Compounds and Demetallation Rates from the Zn(II) Active Site of Metallo-β-lactamases (IMP-1 and IMP-6) Associated with a Single Amino Acid Substitution2022

    • Author(s)
      Yamaguchi Yoshihiro、Kato Koichi、Ichimaru Yoshimi、Uenosono Yuya、Tawara Sakiko、Ito Rio、Matsuse Natsuki、Wachino Jun-ichi、Toma-Fukai Sachiko、Jin Wanchun、Arakawa Yoshichika、Otsuka Masami、Fujita Mikako、Fukuishi Nobuyuki、Sugiura Kirara、Imai Masanori、Kurosaki Hiromasa
    • Journal Title

      ACS Infectious Diseases

      Volume: 9 Issue: 1 Pages: 65-78

    • DOI

      10.1021/acsinfecdis.2c00395

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K06500, KAKENHI-PROJECT-21K15244, KAKENHI-PROJECT-21H02967, KAKENHI-PROJECT-17K08376
  • [Journal Article] Crystal Structures of Metallo-β-Lactamase (IMP-1) and Its D120E Mutant in Complexes with Citrate and the Inhibitory Effect of the Benzyl Group in Citrate Monobenzyl Ester2021

    • Author(s)
      Yamaguchi Yoshihiro、Kato Koichi、Ichimaru Yoshimi、Jin Wanchun、Sakai Misa、Abe Miki、Wachino Jun-ichi、Arakawa Yoshichika、Miyagi Yukina、Imai Masanori、Fukuishi Nobuyuki、Yamagata Yuriko、Otsuka Masami、Fujita Mikako、Kurosaki Hiromasa
    • Journal Title

      Journal of Medicinal Chemistry

      Volume: 64 Issue: 14 Pages: 10019-10026

    • DOI

      10.1021/acs.jmedchem.1c00308

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21H02967, KAKENHI-PROJECT-17K08376
  • 1.  Kurosaki Hiromasa (70234599)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 2.  WACHINO Jun-ichi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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