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Masaoka Toshinori  正岡 利紀

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MASAOKA Toshinori  正岡 利紀

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Researcher Number 70256270
Affiliation (Current) 2025: 東京医科大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help 2018 – 2024: 東京医科大学, 医学部, 准教授
2010 – 2017: 東京医科大学, 医学部, 講師
Review Section/Research Field
Principal Investigator
Biomedical engineering/Biomaterial science and engineering
Except Principal Investigator
Orthopaedic surgery / Basic Section 90140:Medical technology assessment-related / Basic Section 90110:Biomedical engineering-related / Basic Section 56020:Orthopedics-related / Basic Section 26040:Structural materials and functional materials-related
Keywords
Principal Investigator
ポリエチレン / 人工関節 / 超高分子量ポリエチレン / 力学特性 / 微細構造 / ビタミンE / 高度架橋ポリエチレン / 人工股関節
Except Principal Investigator
人工股関節 / 人工股関節置換術 … More / 超高分子量ポリエチレン / 低温劣化 / 構造健全性 / 複合セラミックス / 残留応力 / 加速エージング / DUSP-1 / 変形性関節症 / 微細構造 / ポリエチレンライナー / デラミネーション耐性 / 微構造解析 / 脛骨インサート / 人工膝関節 / 血中金属濃度 / 摩耗 / 偽腫瘍 / 人工股関節摺動面 / TRPA1 / 長期耐用性 / 高度架橋ポリエチレン / 耐疲労性 / 抗酸化性 / 耐摩耗性 / 衝撃疲労試験 / 寛骨臼ライナー / 相変態 / 生体環境劣化 / セラミック / インプラント / エージング / 相転移 / ジルコニア強化型アルミナ / 構造安定性 / セラミック・インプラント / 細胞内情報伝達 / 細胞外基質分解酵素 / 神経成長因子 / 神経侵入 / 軟骨変性 / ラマン分光 / 細胞外マトリックス / ヒト軟骨 / クリープ / ポリエチレン / クリープ変形速度 / 超高分子ポリエチレン / 生体工学 / 人工股関節全置換術 / 股関節シュミレーター Less
  • Research Projects

    (11 results)
  • Research Products

    (12 results)
  • Co-Researchers

    (9 People)
  •  Investigation of the regulatory mechanism of osteoarthritis pathology by TRPA1 stimulation

    • Principal Investigator
      澤地 恭昇
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      Tokyo Medical University
  •  人工股関節周囲組織反応(ALTR)の病態解明に関する基礎的および臨床的検討

    • Principal Investigator
      石田 常仁
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 90110:Biomedical engineering-related
    • Research Institution
      Tokyo Medical University
  •  超長寿命型人工膝関節開発のためのデラミネーション破壊抑制に関する研究

    • Principal Investigator
      高橋 康仁
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 90140:Medical technology assessment-related
    • Research Institution
      Tokyo Medical University
  •  高度架橋ポリエチレン製人工股関節の超長期耐用性の実現を目指した材料設計の至適化

    • Principal Investigator
      立岩 俊之
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 90140:Medical technology assessment-related
    • Research Institution
      Tokyo Medical University
  •  A novel proposal for validating the durability of ceramic-composite artificial hip joints and improving its prediction accuracy

    • Principal Investigator
      TAKAHASHI Yasuhito
    • Project Period (FY)
      2020 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 90140:Medical technology assessment-related
    • Research Institution
      Tokyo Medical University
  •  Clarification of in-vivo fracture mechanisms of ceramic acetabular liner toward the safety improvement

    • Principal Investigator
      SHISHIDO Takaaki
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 26040:Structural materials and functional materials-related
    • Research Institution
      Tokyo Medical University
  •  Regulation of cartilage degeneration and innervation by DUSP-1 in the development of osteoarthritis

    • Principal Investigator
      Sawaji Yasunobu
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Tokyo Medical University
  •  Elucidation of the effects of antioxidant incorporation on molecular structure and mechanical properties in polyethylene hip joint prosthesesPrincipal Investigator

    • Principal Investigator
      MASAOKA Toshinori
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biomedical engineering/Biomaterial science and engineering
    • Research Institution
      Tokyo Medical University
  •  Clarification of collagen degeneration mechanisms by NIR-Raman spectroscopy and development of a novel optical biopsy system

    • Principal Investigator
      TAKAHASHI Yasuhito
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Tokyo Medical University
  •  Effect of acetabular liner thickness on creep resistance in HXLPE for total joint replacement: deformation rate and molecular structure

    • Principal Investigator
      YAMAMOTO Kengo
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Tokyo Medical University
  •  Hip simulator study of wear characteristics of UHMWPE liner

    • Principal Investigator
      YAMAMOTO Kengo
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Tokyo Medical University

All 2018 2017 2016 2014

All Journal Article Presentation

  • [Journal Article] Size and thickness effect on creep deformation of conventional and vitamin E-diffused highly crosslinked UHMWPE in total hip arthroplasty2016

    • Author(s)
      Yasuhito Takahashi , Toshiyuki Tateiwa, Takaaki Shishido, Toshinori Masaoka, Kosuke Kubo, Kengo Yamamoto
    • Journal Title

      Journal of the Mechanical Behavior of Biomedical Materials

      Volume: 印刷中 Pages: 399-406

    • DOI

      10.1016/j.jmbbm.2016.05.020

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25462383
  • [Journal Article] Improved resistance to neck-liner impingement in second-generation highly crosslinked polyethylene - The role of vitamin E and crosslinks2016

    • Author(s)
      Takahashi Y, Tateiwa T, Pezzotti G, Shishido T, Masaoka T, Yamamoto K
    • Journal Title

      The Journal of Arthroplasty

      Volume: 31 Issue: 12 Pages: 2926-2932

    • DOI

      10.1016/j.arth.2016.05.049

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K01316
  • [Journal Article] 変形性関節症に対する薬物治療の展望2016

    • Author(s)
      澤地恭昇,宮本泰典,依藤麻紀子,正岡利紀,宍戸孝明,山本謙吾
    • Journal Title

      整形・災害外科

      Volume: 59 Pages: 1181-1188

    • Data Source
      KAKENHI-PROJECT-16K10840
  • [Journal Article] Vitamin-E blended and infused highly cross-linked polyethylene for total hip arthroplasty: A comparison of three-dimensional crystalline morphology and strain recovery behavior2014

    • Author(s)
      Yasuhito Takahashi, Toshinori Masaoka, Kengo Yamamoto, Takaaki Shishido, Toshiyuki Tateiwa, Kosuke Kubo, Giuseppe Pezzotti
    • Journal Title

      Journal of the mechanical behavior of biomedical materials

      Volume: 36 Pages: 59-70

    • DOI

      10.1016/j.jmbbm.2014.04.004

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25462383
  • [Presentation] DUSP-1 Involves In The Mechanism Of PGE2 Suppression Of MMPs And NGF In Human Synovial Cells2018

    • Author(s)
      Asato Maekawa, Yasunobu Sawaji, Kenji Endo, Takuya Kusakabe, Takamitu Konishi, Toshiyuki Tateiwa, Toshinori Masaoka, Takaaki Shishido, Kengo Yamamoto
    • Organizer
      The 28th Japanese-Korean Combined Orthopaedic Symposium
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10840
  • [Presentation] DUSP-1によるヒト変形性関節症の軟骨変性および神経侵入制御の解明2018

    • Author(s)
      前川麻人,澤地恭昇,遠藤健司,日下部拓哉,小西隆允,正岡利紀,宍戸孝明,山本 謙吾
    • Organizer
      第11回日本運動器疼痛学会
    • Data Source
      KAKENHI-PROJECT-16K10840
  • [Presentation] ヒト関節滑膜細胞におけるPGE2によるNGFおよびMMP発現抑制へのDUSP1の関与2018

    • Author(s)
      前川麻人,澤地恭昇,遠藤健司, 日下部拓哉,小西隆允,正岡利紀,宍戸孝明,山本謙吾
    • Organizer
      第16回整形外科痛みを語る会
    • Data Source
      KAKENHI-PROJECT-16K10840
  • [Presentation] DUSP-1によるヒト変形性関節症の軟骨変性および神経侵入制御の解明2018

    • Author(s)
      前川麻人,澤地恭昇,遠藤健司, 日下部拓哉,小西隆允,立岩俊之,正岡利紀,山本謙吾
    • Organizer
      第33回日本整形外科学会基礎学術集会
    • Data Source
      KAKENHI-PROJECT-16K10840
  • [Presentation] 高度架橋ポリエチレン摺動面の現況と展望 - 1st vs. 2nd generation2017

    • Author(s)
      髙橋康仁、宍戸孝明、正岡利紀、立岩俊之、Giuseppe Pezzotti、山本謙吾
    • Organizer
      第44回日本股関節学会学術集会
    • Data Source
      KAKENHI-PROJECT-15K01316
  • [Presentation] Vitamin E混合は高架橋UHMWPEライナーの微細構造および力学挙動に影響するのか?2016

    • Author(s)
      高橋康仁、Giuseppe Pezzotti、宍戸孝明、正岡利紀、立岩俊之、久保宏介、山本謙吾
    • Organizer
      第46回日本人工関節学会
    • Place of Presentation
      グランフロント大阪
    • Year and Date
      2016-02-26
    • Data Source
      KAKENHI-PROJECT-25462383
  • [Presentation] Vitamin E混合は高架橋UHMWPEライナーの微細構造および力学挙動に影響するのか?2016

    • Author(s)
      高橋康仁、Giuseppe Pezzotti、宍戸孝明、正岡利紀、立岩俊之、久保宏介、山本謙吾
    • Organizer
      第46回日本人工関節学会
    • Place of Presentation
      グランフロント大阪
    • Year and Date
      2016-02-26
    • Data Source
      KAKENHI-PROJECT-15K01316
  • [Presentation] 変形性関節症の病態形成過程における選択的COX-2阻害剤の有用性の相違2016

    • Author(s)
      澤地恭昇,依藤麻紀子,宮本泰典,立岩俊之,正岡利紀,宍戸孝明,山本謙吾
    • Organizer
      第31回 日本整形外科学会基礎学術集会
    • Place of Presentation
      福岡国際会議場 (福岡県福岡市)
    • Year and Date
      2016-10-13
    • Data Source
      KAKENHI-PROJECT-16K10840
  • 1.  YAMAMOTO Kengo (10246316)
    # of Collaborated Projects: 11 results
    # of Collaborated Products: 12 results
  • 2.  SHISHIDO Takaaki (70266500)
    # of Collaborated Projects: 10 results
    # of Collaborated Products: 11 results
  • 3.  TATEIWA Toshiyuki (00424630)
    # of Collaborated Projects: 10 results
    # of Collaborated Products: 9 results
  • 4.  TAKAHASHI Yasuhito (60567668)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 5 results
  • 5.  Sawaji Yasunobu (20571152)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 6 results
  • 6.  久保 宏介 (40408092)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  遠藤 健司 (90266479)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 8.  石田 常仁 (10453721)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  MAEKAWA Asato
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results

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