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Ide Yoshihiro  井出 良浩

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IDE Yoshihiro  井出 良浩

井出 良浩  イデ ヨシヒロ

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Researcher Number 70258606
Affiliation (Current) 2025: 兵庫医科大学, 医学部, 講師
Affiliation (based on the past Project Information) *help 2012: 神戸大学, 大学院・医学研究科, 助教
2010 – 2011: 神戸大学, 医学研究科, 助教
1999: 筑波大学, 基礎医学系, 講師
Review Section/Research Field
Principal Investigator
Human pathology
Except Principal Investigator
Human pathology / Gastroenterology
Keywords
Principal Investigator
動物モデル / 動脈硬化 / 遺伝子操作 / ウサギ / VEGF
Except Principal Investigator
lipoproteins / transgene / atherosclerosis / hypercholesterolemia / 動物モデル … More / リポ蛋白 / 動脈硬化 / トランスジェニックウサギ / transgenic rabbit / animal models / animal cloning / clone / 細胞核融合 / 体細胞クローン / ウサギ / 遺伝子操作 / 卵細胞活性化 / 単為発生 / クローンウサギ / 体細胞核移植技術 / transgenic rahbit / HDL / metabolism / apoproteins / 脂質代謝 / 遺伝子導入モデル / アポ蛋白 / レムナントリポ蛋白 / リパーゼ / 高脂血症 / リポ蛋白代謝 / 遺伝子導入動物 / HCV JFH-1 / レプリコン / レポーター / hnRNPF / hnRNPH / コア蛋白質 / 宿主因子 / NS5A蛋白質 / ウイルス産生 / HCV / C型肝炎 / 肝臓学 Less
  • Research Projects

    (4 results)
  • Research Products

    (30 results)
  • Co-Researchers

    (8 People)
  •  The study of molecular mechanism of hepatitis C virusproduction

    • Principal Investigator
      SHOJI Ikuo
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Kobe University
  •  動脈硬化研究のためのヒトVEGF過剰発現トランスジェニックウサギの作製Principal Investigator

    • Principal Investigator
      井出 良浩
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Human pathology
    • Research Institution
      University of Tsukuba
  •  FUNCTIONAL ROLE OF LIPOPROTEIN LIPASE IN ATHEROGENESIS - A STUDY ON TRANSGENIC RABBITS EXPRESSING HUMAN LIPOPROTEIN LIPASE

    • Principal Investigator
      FAN Jianglin
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Human pathology
    • Research Institution
      UNVERSITY OF TSUKUBA
  •  DEVELOPMENT OF CLONE TRANSGENIC RABBITS FOR THE STUDY OF ATHEROSCLEROSIS

    • Principal Investigator
      WATANABE Teruo
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Human pathology
    • Research Institution
      SAGA MEDICAL SCHOOL
      University of Tsukuba

All 2012 2011 2010

All Journal Article Presentation

  • [Journal Article] Sequence heterogeneity in NS5A of hepatitis C virus gentypes 2a and 2b and clinical outcome of pegylated-Interferon/Ribavirin therapy2012

    • Author(s)
      El-Shamy, A., Shoji, I., Kim S-R., Ide, Y-H., Imoto, S., Deng, L., Yoon, S., Fujisawa, T., Tani, S., Yano, Y., Seo, Y., Azuma, T., and Hotta, H
    • Journal Title

      PLoS One

      Volume: 7 Pages: 1-10

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590731
  • [Journal Article] Polymorphisms of hepatitis C virus NS5A and core proteins and clinical outcome of pegylated interferon/ribavirin therapy2012

    • Author(s)
      El-Shamy A, Ide Y-H, Kim SR, Sasase N, Imoto S, Deng L, Shoji I, Hotta H
    • Journal Title

      Inervirology

      Volume: 55 Issue: 1 Pages: 1-11

    • DOI

      10.1159/000322219

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590731, KAKENHI-PROJECT-23590543
  • [Journal Article] Polymorphisms of hepatitis C virus NS5A and core proteins and clinical outcome of pegylated interferon/ribavirin therapy2012

    • Author(s)
      El-Shamy, A., Ide, Y-H., Kim, SR., Sasase, N., Imoto, S., Deng, L., Shoji, I., and Hotta, H.
    • Journal Title

      Intervirology

      Volume: 55 Pages: 1-11

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590731
  • [Journal Article] A point mutation at Asn-534 that disrupts a conserved N-glycosylation motif of the E2 glycoprotein of hepatitis C virus markedly enhances the sensitivity to antibody neutralization2012

    • Author(s)
      Sasayama M., Shoji I., Ide Y-H., Deng L., Hotta H
    • Journal Title

      Journal of Medical Virology

      Volume: 84 Issue: 2 Pages: 229-234

    • DOI

      10.1002/jmv.22257

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590731, KAKENHI-PROJECT-23590543
  • [Journal Article] Hepatitis C virus infection promotes hepatic gluconeogenesis through an NS5A-mediated, FoxO1-dependent pathway2011

    • Author(s)
      Deng, L., Shoji, I., Oawa, W., Kaneda, S., Soga, T., Jiang, D. P., Ide, Y-H., and Hotta, H
    • Journal Title

      Journal of Virology

      Volume: 85 Pages: 8556-68

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590731
  • [Journal Article] Hepatitis C Virus Infection Promotes Hepatic Gluconeogenesis through an NS5A-Mediated, FoxO1-Dependent Pathway2011

    • Author(s)
      Deng, L.
    • Journal Title

      J.Virol.

      Volume: 85 Issue: 17 Pages: 8556-8568

    • DOI

      10.1128/jvi.00146-11

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22134007, KAKENHI-PROJECT-22590731, KAKENHI-PROJECT-23590543
  • [Journal Article] Potential therapeutic application of intravenous bone marrow infusion in patients with alcoholic liver cirrhosis2011

    • Author(s)
      Saito T, Okumoto K, Haga H, Nishise Y, Ishii R, Sato C, Watanabe H, Okada A, Ikeda M, Togashi H, Ishikawa T, Terai S, Sakaida I, Kawata S
    • Journal Title

      Stem Cells Dev

      Volume: 20 Issue: 6 Pages: 1503-1510

    • DOI

      10.1111/j.1348-0421.2011.00331.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590824, KAKENHI-PROJECT-22590731, KAKENHI-PROJECT-23590543
  • [Journal Article] Sequence heterogeneity of NS5A and core proteins of hepatitis C virus and virological responses to Pegylated-Interferon/Ribavirin combination therapy2011

    • Author(s)
      El-Shamy, A., Shoji, I., Saito, T., Watanabe H., Ide, Y-H., Deng, L., Kawata, S., and Hotta, H.
    • Journal Title

      Microbiology and Immunology

      Volume: 55 Pages: 418-26

    • NAID

      10031121486

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590731
  • [Journal Article] 17β-Estradiol inhibits the production of infectious particles of hepatitis C virus.2010

    • Author(s)
      Hayashida K, Shoji, I., Deng, L., Ide, Y-H., Hotta, H.
    • Journal Title

      Microbiology and Immunology

      Volume: 54 Pages: 684-690

    • NAID

      10029546273

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590731
  • [Journal Article] Estradiol inhibits the production of infectious particles of hepatitis C virus2010

    • Author(s)
      Hayashida K, Shoji, I., Deng, L., Ide, Y-H., and Hotta, H. 17
    • Journal Title

      Microbiology and Immunology

      Volume: 54 Pages: 684-90

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590731
  • [Presentation] C 型肝炎ウイルス NS5A の新規結合タンパク質であるヒストンメチル基転移酵素SMYD3 の同定2011

    • Author(s)
      甘翔、Lin Deng、陳明、井出良浩、勝二郁夫、堀田博
    • Organizer
      第64回日本細菌学会関西支部総会
    • Place of Presentation
      大阪
    • Year and Date
      2011-11-19
    • Data Source
      KAKENHI-PROJECT-22590731
  • [Presentation] C型肝炎ウイルスNS5Aの新規結合タンパク質であるヒストンメチル基転移酵素SMYD3の同定2011

    • Author(s)
      甘翔、Lin Deng、陳明、井出良浩、勝二郁夫、堀田博
    • Organizer
      第64回日本細菌学会関西支部総会
    • Place of Presentation
      大阪府立大学(堺市)
    • Year and Date
      2011-11-19
    • Data Source
      KAKENHI-PROJECT-22590731
  • [Presentation] Identification of an E3 ubiquitin ligase that mediates ubiquitylation of hepatitis C virus NS5A protein2011

    • Author(s)
      Shoji I, Okada N, Gan X, Miyagawa S, Makimoto M, Chieko M, Jang DP, Deng L, Ide Y-H, andHotta H
    • Organizer
      第34回日本分子生物学会年
    • Place of Presentation
      横浜
    • Year and Date
      2011-12-14
    • Data Source
      KAKENHI-PROJECT-22590731
  • [Presentation] Identification of an E3 ubiquitin ligase that targets hepatitis C virus NS5A protein for ubiquitylation.2011

    • Author(s)
      Shoji I, Okada N, Gan X, Miyagawa S, MakimotoM, El-Shamy A, Deng L, Jang DP, IdeY-H, and Hotta H
    • Organizer
      18thInternational symposium on hepatitis C virus and related viruses
    • Place of Presentation
      Seattle, USA
    • Year and Date
      2011-09-10
    • Data Source
      KAKENHI-PROJECT-22590731
  • [Presentation] Identification of an E3 ubiquitin ligase that mediates ubiquitylation of hepatitis C virus NS5A protein2011

    • Author(s)
      Shoji I, Okada N, Gan X, Miyagawa S, Makimoto M, El-Shamy A, Deng L, Jang DP, Ide Y-H, Hotta H
    • Organizer
      International Union of Microbiological Societies 2011 Congress
    • Place of Presentation
      札幌コンベンションセンター(札幌市)
    • Year and Date
      2011-09-16
    • Data Source
      KAKENHI-PROJECT-22590731
  • [Presentation] Identification of an E3 ubiquitin ligase that targets hepatitis C virus NS5A protein for ubiquitylation2011

    • Author(s)
      Shoji I, Okada N, Gan X, Miyagawa S, Makimoto M, El-Shamy A, Deng L, Jang DP, Ide Y-H, Hotta H
    • Organizer
      18^<th> International symposium on hepatitis C virus and related viruses
    • Place of Presentation
      シアトルシェラトンホテル(シアトル、米国)
    • Year and Date
      2011-09-10
    • Data Source
      KAKENHI-PROJECT-22590731
  • [Presentation] Identification of an E3 ubiquitin ligase that mediates ubiquitylation of hepatitis C virus NS5A protein2011

    • Author(s)
      Shoji I, Okada N, Gan X, Miyagawa S, Makimoto M, El-Shamy A, Deng L, Jang DP, Ide Y-H, and Hotta H
    • Organizer
      International Union of Microbiological Societies 2011 Congress
    • Place of Presentation
      札幌
    • Year and Date
      2011-09-16
    • Data Source
      KAKENHI-PROJECT-22590731
  • [Presentation] Identification of an E3 ubiquitin ligase that mediates ubiquitylation of hepatitis C virus NS5A protein2011

    • Author(s)
      Shoji I, Okada N, Gan X, Miyagawa S, Makimoto M, Chieko M, Jang DP, Deng L, Ide Y-H, Hotta H
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Year and Date
      2011-12-14
    • Data Source
      KAKENHI-PROJECT-22590731
  • [Presentation] HCV-induced generation of reactive oxygen species leads to Bax-mediated apoptosis through activation of the c-Jun NH_2-terminal kinase signaling pathway.2010

    • Author(s)
      Deng L, Ide Y-H, Shoji I, Hotta H.
    • Organizer
      17th International Meeting on hepatitis C virus and related viruses.
    • Place of Presentation
      パシフィコ横浜(神奈川県)
    • Data Source
      KAKENHI-PROJECT-22590731
  • [Presentation] 糖代謝に及ぼすC型肝炎ウイルスの影響及びその分子機序の解析2010

    • Author(s)
      Deng L, 兼田崇作, 井出良浩, 勝二郁夫,堀田博
    • Organizer
      第58回日本ウイルス学会学術集会
    • Place of Presentation
      徳島
    • Data Source
      KAKENHI-PROJECT-22590731
  • [Presentation] C型肝炎ウイルス感染は糖新生系を亢進し、糖尿病発症に関与する2010

    • Author(s)
      堀田博、井出良浩、勝二郁夫
    • Organizer
      第46回日本肝臓学会総会
    • Place of Presentation
      ホテルメトロポリタン山形(山形県)
    • Data Source
      KAKENHI-PROJECT-22590731
  • [Presentation] 糖代謝に及ぼすC型肝炎ウイルスの影響及びその分子機序の解析2010

    • Author(s)
      Deng L, 兼田崇作、井出良浩、勝二郁夫、堀田博
    • Organizer
      第58回日本ウイルス学会学術集会
    • Place of Presentation
      あわぎんホール(徳島県)
    • Data Source
      KAKENHI-PROJECT-22590731
  • [Presentation] C型肝炎ウイルスNS5Aに結合するユビキチンリガーゼの同定2010

    • Author(s)
      岡田典子、勝二郁夫、甘翔、Deng L、姜大鵬、井出良浩、堀田博
    • Organizer
      第33回日本分子生物学会年会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-22590731
  • [Presentation] E6AP uibiquitin ligase mediates ubiquitin-dependent degradation of peroxiredoxin 1.2010

    • Author(s)
      Shoji I, Nasu J, Murakami K, Miyagawa S, Yamashita R, Ichimura T, Wakita T, Ide Y-H, Hotta H, Miyamura T, Suzuki T, Satoh T.
    • Organizer
      第33回日本分子生物学会年会(BMB2010)
    • Place of Presentation
      神戸国際展示場(兵庫県)
    • Data Source
      KAKENHI-PROJECT-22590731
  • [Presentation] Molecular mechanism of HCV-induced suppression of glucose transporter (GLUT)2 expression.2010

    • Author(s)
      Shoji I, Kaneda S, Deng L, Ide Y-H, Hotta H.
    • Organizer
      17th International Meeting on hepatitis C virus and related viruses.
    • Place of Presentation
      パシフィコ横浜(神奈川県)
    • Data Source
      KAKENHI-PROJECT-22590731
  • [Presentation] C型肝炎ウイルスNS5Aに結合するユビキチンリガーゼの同定2010

    • Author(s)
      岡田典子、勝二郁夫、甘翔、Deng L、姜大鵬、井出良浩、堀田博
    • Organizer
      第33回日本分子生物学会年会(BMB2010)
    • Place of Presentation
      神戸国際展示場(兵庫県)
    • Data Source
      KAKENHI-PROJECT-22590731
  • [Presentation] Molecular mechanism of HCVinduced suppression of glucose transporter(GLUT)2 expression.2010

    • Author(s)
      Shoji I, Kaneda S, Deng L, Ide Y-H,Hotta H.
    • Organizer
      17thInternational Meeting on hepatitis C virus and related viruses
    • Place of Presentation
      Yokohama, Kanagawa
    • Data Source
      KAKENHI-PROJECT-22590731
  • [Presentation] C型肝炎ウイルス感染は糖新生系を亢進し、糖尿病発症に関与する2010

    • Author(s)
      堀田博、井出良浩、勝二郁夫
    • Organizer
      第46回日本肝臓学会総会
    • Place of Presentation
      山形
    • Data Source
      KAKENHI-PROJECT-22590731
  • [Presentation] E6AP uibiquitin ligase mediatesubiquitin-dependent degradation of peroxiredoxin 12010

    • Author(s)
      Shoji I, Nasu J, Murakami K, Miyagawa S, Yamashita R, IchimuraT, Wakita T, Ide Y-H, Hotta H, Miyamura T, Suzuki T,Satoh T
    • Organizer
      第33回日本分子生物学会年会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-22590731
  • [Presentation] HCV-induced generation of reactive oxygen species leads to Bax-mediated apoptosis through activation of the c-Jun NH_2-terminal kinase signaling pathway.2010

    • Author(s)
      Deng L, Ide YH, Shoji I, Hotta H
    • Organizer
      17th International Meeting on hepatitis C virus and related viruses.
    • Place of Presentation
      Yokohama, Kanagawa.
    • Data Source
      KAKENHI-PROJECT-22590731
  • 1.  FAN Jianglin (60272192)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 2.  SHOJI Ikuo (40356241)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 28 results
  • 3.  UNOKI Hiroyuki (40323290)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  WATANABE Teruo (40037396)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  KIMOTO Masao (40153225)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  長崎 比呂央 (50318664)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  HONDA Kazuo
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  斎藤 貴史
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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