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KITAMURA Osamu  北村 修

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北村 修  キタムラ オサム

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Researcher Number 70266609
Other IDs
Affiliation (Current) 2025: 杏林大学, 医学部, 教授
Affiliation (based on the past Project Information) *help 2015 – 2021: 杏林大学, 医学部, 教授
2007 – 2014: Kanazawa Medical University, 医学部, 教授
2006: The Univ.of Tokushima, Inst.of Health Biosciences, Lecturer, 大学院ヘルスバイオサイエンス研究部, 講師
2004 – 2005: The Univ.of Tokushima, Institute of Health Biosciences, Lecturer, 大学院・ヘルスバイオサイエンス研究部, 講師
2000 – 2002: The University of Tokushima, School of Medicine, Department of Legal Medicine, Assistant-professor., 医学部, 講師 … More
1999: 徳島大学, 医学部, 助手
1997 – 1998: 東京慈恵会医科大学, 医学部, 助手
1997 – 1998: 東京慈恵会医科大学, 医学部・法医学, 助手
1996: 東京慈恵会医科大学, 医学部・法医学教室, 助手
1995: 東京慈恵会医科大学, 医学部・法医学, 助手 Less
Review Section/Research Field
Principal Investigator
Legal medicine / Legal medicine
Except Principal Investigator
Legal medicine / Legal medicine / Basic Section 58040:Forensics medicine-related
Keywords
Principal Investigator
覚醒剤 / アストロサイト / 免疫組織化学的染色 / 神経細胞 / 法医病理学 / 熱ショック蛋白質 / 神経栄養因子 / 細胞骨格蛋白 / Mitochondrial DNA / Brain-derived neurotrophic factor … More / Striatum / Caspase-3 / Microglia / Astrocyte / Dopaminergic terminal markers / Methamphetamine / 剖検 / PCR / 免疫組織学学的染色 / 脳由来神経栄養因子 / ミトコンドリアDNA / ミクログリア / caspase-3 / 線条体 / ドパミン作動性神経終末マーカー / ポリクローナル抗体 / カスパーセ / カスパーゼ / カルパイン / スペクトリン分解産物 / 頭部外傷 / 小胞体ストレス / グリア細胞 / 酸化ストレス / 薬物自己投与 / ウェタンブロッティング / パラフィン包埋ブロック / サイトカイン / 熱ショックタンパク質 / 血管障害 / 海馬 / 高体温症 / 房室結節 / 洞結節 / 心臓 / アポトーシス / 突然死 / 刺激伝導系 / 癌遺伝子産生蛋白 / 虚血・低酸性脳障害 / 心臓突然死 / 有機溶剤 … More
Except Principal Investigator
免疫組織化学 / 覚せい剤 / cause of death / oxidative damage / 8-hydroxy-2'-deoxyguanosine / 過酸化障害 / 死因 / immunohistochemistry / ACTH / 法医学 / 線条体 / peroxidative DNA injury / methamphetamine / トルエン / adrenocorticotrophine / トルエン吸入 / 薬物濫用 / forensic pathology / 法医病理学 / 酸化ストレス / 覚醒剤 / グルタミン酸トランスポーター / 刺激性薬物 / 蛍光免疫染色 / 側坐核 / 脳 / ヒト / VGLUT / 視床 / 動物実験 / 小胞体ストレス / western blotting / rat / midbrain / striatum / Western blotting / 覚せい剤濫用 / VGLUT2 / c-fos / GAD67 / 黒質線条体路 / 濫用初期 / モデル動物 / creatine / blood cortisol / 血中cortisol / クレアチニン / 血中コルチゾール / 酸化的DNA損傷 / myoglobin / skeletal muscle damage / renal function / c-Fos / HSP70 / 腎臓 / 骨格筋 / CPK / 尿細管傷害 / 8-OH-dG / 酸化的DNA 傷害 / 腎機能障害 / 酸化的DNA傷害 / ミオグロビン / 骨格筋障害 / 腎機能 / adrenocorticotropine / cardiac sudden death / forensic toxicology / thinner abuse / superoxide dismutase / 心筋細胞 / 副腎皮質ホルモン / 心臓突然死 / 過酸化傷害 / 法医中毒学 / シンナー濫用 / morphology / testis / spermatogenesis / toluene / abused organic solvent / legal medicine / 形態学 / 精巣 / 造精機能 / 濫用薬物 / neuronal changes / neurotrofic factor / adrenal gland / toluene inhalation / drug abuse / forensic medicine / GDNF / TGF-β1 / コルチコステロン / アルドステロン / 神経細胞変化 / 神経栄養因子 / 副腎 / gun shot wound / stabb wound / simulation / computer graphics / 3D imaging / 画像計測 / 突然死 / 法医解剖 / 3次元画像 / 画像解析 / 射創 / 刺創 / 法医病理 / コンピュータグラフィクス / シミュレーション / コンピュータグラフィックス / 射傷 / 創傷 / シュミレーション / コンピュータグフィックス / 三次元画像 / 下垂体 / 免疫組織学的染色 / HPA axis / 免疫組織化学染色 / HPA axis / 免疫組織化学的染色 / HPA axis / 下垂体病変 / 自殺 / シンヌクレオパシー / 神経毒性 / グリオーシス / エピジェネティックス / 薬物依存 / 神経細胞障害 Less
  • Research Projects

    (17 results)
  • Research Products

    (15 results)
  • Co-Researchers

    (14 People)
  •  Histological analysis of stimulant drug abuse using Immunofluorescence.

    • Principal Investigator
      Takeichi Toshiaki
    • Project Period (FY)
      2018 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 58040:Forensics medicine-related
    • Research Institution
      Kyorin University
  •  Analysis to the nigrostriatal pathway of the low-dose methamphetamine preadministration.

    • Principal Investigator
      TAKEICHI Toshiaki
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Legal medicine
    • Research Institution
      Kanazawa University
  •  Investigation on the piruitary glands in cases of suicide

    • Principal Investigator
      OH RO
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Legal medicine
    • Research Institution
      Kyorin University
      Kanazawa Medical University
  •  Immunohistochemical studies on neuronal injuries in the brain stem of traumatic head injury casesPrincipal Investigator

    • Principal Investigator
      KITAMURA Osamu
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Legal medicine
    • Research Institution
      Kanazawa Medical University
  •  Investigation on synucleinopathy and epigenetic mechanisms in the brains of methamphetamine abusers

    • Principal Investigator
      OH RO
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Legal medicine
    • Research Institution
      Kanazawa Medical University
  •  Investigations on methamphetamine-neurotoxicity by using an animal modelPrincipal Investigator

    • Principal Investigator
      KITAMURA Osamu
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Legal medicine
    • Research Institution
      Kanazawa Medical University
  •  Detection of hyperthermia and vascular damages induced by methamphetamine in forensic autopsy casesPrincipal Investigator

    • Principal Investigator
      KITAMURA Osamu
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Legal medicine
    • Research Institution
      Kanazawa Medical University
  •  Evaluation of stress relation for forensic autopsy diagnosis: Meaning of DNA damage material in urine and stress hormone

    • Principal Investigator
      KUBO Shin-ichi
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Legal medicine
    • Research Institution
      The University of Tokushima
  •  Analysis of methamphetamine-induced neurotoxicity in the striatum of autopsied brainsPrincipal Investigator

    • Principal Investigator
      KITAMURA Osamu
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Legal medicine
    • Research Institution
      The University of Tokushima
  •  Research on antemortem condition elucidation of methamphetamine detected forensic autopsy cases : investigation of trouble of skeletal muscle and kidney

    • Principal Investigator
      KUBO Shin-ichi
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Legal medicine
    • Research Institution
      The University of Tokushima
  •  Experimental study of generation mechanism of thinner abuser's sudden death: Molecular biological examination of myocardial damage

    • Principal Investigator
      KUBO Shinichi
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Legal medicine
    • Research Institution
      The University of Tokushima, School of Medicine
  •  The influence to the spermatogenesis of the abused organic solvent : morphological changes and molecular biological investigation for functional disorder of spermatogenesis

    • Principal Investigator
      TOKUNAGA Itsuo
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Legal medicine
    • Research Institution
      The University of Tokushima
  •  Studies for the mechanism of adrenal hypertrophy induced by toluene inhalation, and endocrinological changes in adrenal gland

    • Principal Investigator
      KUBO Shin-ichi
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Legal medicine
    • Research Institution
      Department of Legal Medicine, School of Medicine, The university of Tokushima
  •  覚醒剤中毒剖検例における心刺激伝導系の免疫組織化学的検討Principal Investigator

    • Principal Investigator
      北村 修
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Legal medicine
    • Research Institution
      Jikei University School of Medicine
  •  Application of 4D imaging and compter graphics in the region of forensic pathology

    • Principal Investigator
      TAKATSU Akihiro
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Legal medicine
    • Research Institution
      Jikei University School of Medicine
  •  神経細胞の病理学的変化による心臓突然死の病態の評価-免疫組織学的検討-Principal Investigator

    • Principal Investigator
      北村 修
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Legal medicine
    • Research Institution
      Jikei University School of Medicine
  •  覚醒剤及び有機溶剤中毒における脳組織の免疫組織化学的研究Principal Investigator

    • Principal Investigator
      北村 修
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Legal medicine
    • Research Institution
      Jikei University School of Medicine

All 2020 2019 2017 2016 2015 2012 2010 2008 Other

All Journal Article Presentation

  • [Journal Article] Pre-administration of low-dose methamphetamine enhances movement and neural activity after high-dose methamphetamine administration in the striatum2019

    • Author(s)
      Takeichi T, Hori O, Hattori T, Kiryu K, Zuka M, Kitamura O
    • Journal Title

      Neurosci Lett

      Volume: 703 Pages: 119-124

    • DOI

      10.1016/j.neulet.2019.03.023

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K06500, KAKENHI-PROJECT-18K10121, KAKENHI-PROJECT-18KK0255, KAKENHI-PROJECT-18K06501, KAKENHI-PROJECT-18K10120, KAKENHI-PROJECT-18KK0435
  • [Journal Article] The effect of low-dose methamphetamine pretreatment on endoplasmic reticulum stress and methamphetamine neurotoxicity in the rat midbrain2012

    • Author(s)
      Takeichi T, Wang EL, Kitamura O
    • Journal Title

      Legal Medicine

      Volume: 14 Pages: 69-77

    • Data Source
      KAKENHI-PROJECT-21390217
  • [Journal Article] Microglial and astrocytic changes in the striatum of methamphetamine abusers2010

    • Author(s)
      Osamu Kitamura, 他
    • Journal Title

      Legal Medicine

      Volume: 12 Pages: 57-62

    • NAID

      10029882766

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590674
  • [Journal Article] Detection of methamphetamine neurotoxicity in forensic autopsy cases.

    • Author(s)
      Osamu Kitamura
    • Journal Title

      Legal Medicine (印刷中)

    • NAID

      10027262070

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590674
  • [Journal Article] Immunohistochemical investigation of dopaminergic terminalmarkers and caspase-3 activation in the striatum of human methamphetamine users

    • Author(s)
      Osamu Kitamura
    • Journal Title

      International Journal of Legal Medicine (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590579
  • [Journal Article] Immunohistochemical investigation of dopaminergic terminal markers and caspase-3 activation in the striatum of human methamphetamine users

    • Author(s)
      Osamu Kitamura
    • Journal Title

      International Journal of Legal Medicine (印刷中)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590579
  • [Journal Article] Detection of methamphetamine neurotoxicity in forensic autopsy cases

    • Author(s)
      Osamu Kitamura
    • Journal Title

      Legal Medicine (印刷中)

    • NAID

      10027262070

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590674
  • [Journal Article] Immunohistochemical investigationof dopaminergic terminal markers and caspase-3 activation in the striatum of human methamphetamine users.

    • Author(s)
      Osamu Kitamura
    • Journal Title

      International Journal of Legal Medicine (印刷中)

    • Data Source
      KAKENHI-PROJECT-17590579
  • [Presentation] 急性心筋梗塞事例を用いた心臓組織における脱リン酸化Connexin43の検討2020

    • Author(s)
      武市敏明,桐生京佳,山田真嗣,吉田昌記,高篠智,高橋かすみ,北村修.
    • Organizer
      第104次 日本法医学会学術全国集会
    • Data Source
      KAKENHI-PROJECT-18K10121
  • [Presentation] Methamphetamine反復投与における線条体およひ中脳の神経マーカーと運動量の解析2017

    • Author(s)
      武市敏明、北村修、王路、塚正彦
    • Organizer
      第101次日本法医学会学術全国集会
    • Data Source
      KAKENHI-PROJECT-15K08888
  • [Presentation] 自殺剖検例における下垂体の検討:Rathke嚢胞による前葉細胞の病理学的変化2016

    • Author(s)
      王 路、武市 敏明、高木 徹也、高篠 智、吉田 昌記、山田千歩、氣賀澤秀明、岩楯桜子、髙橋かすみ、北村 修
    • Organizer
      第100次日本法医学会学術全国集会
    • Place of Presentation
      きゅりあん(品川区総合区民センター)
    • Data Source
      KAKENHI-PROJECT-26460892
  • [Presentation] 自殺例における下垂体の病理組織学的検討2015

    • Author(s)
      王路、武市敏明、北村修
    • Organizer
      第99次日本法医学会学術全国集会
    • Place of Presentation
      高知市文化プラザホール
    • Year and Date
      2015-06-12
    • Data Source
      KAKENHI-PROJECT-26460892
  • [Presentation] 自殺例における下垂体疾患2015

    • Author(s)
      北村 修
    • Organizer
      金沢医科大学平成25年度戦略プロジェクト研究発表会
    • Place of Presentation
      金沢医科大学
    • Year and Date
      2015-04-25
    • Data Source
      KAKENHI-PROJECT-26460892
  • [Presentation] Detection of methamphetamine neurotoxicity in forensic autopsy cases2008

    • Author(s)
      Osamu Kitamura
    • Organizer
      7th International Symposium Advanced in Legal Medicine
    • Place of Presentation
      大阪市公会堂
    • Year and Date
      2008-09-04
    • Data Source
      KAKENHI-PROJECT-19590674
  • [Presentation] Detection of methamphetamine neurotoxicity in forensic autopsy cases.2008

    • Author(s)
      Osamu Kitamura
    • Organizer
      7^<th> International Symposium Advanced in Legal Medicine
    • Place of Presentation
      大阪市、大阪市公会堂
    • Year and Date
      2008-09-04
    • Data Source
      KAKENHI-PROJECT-19590674
  • 1.  KUBO Shin-ichi (10205122)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 0 results
  • 2.  OH Ro (60555051)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 4 results
  • 3.  GOTOHDA Takako (50304506)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 4.  TAKEICHI Toshiaki (90460360)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 5 results
  • 5.  TOKUNAGA Itsuo (30116842)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 6.  TAKASHINO Satoshi (50365201)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  TAKATSU Akihiro (60010089)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  SHIGETA Akio (80147321)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  SUZUKI Naoki (40147327)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  MORITA Kyouji (50108883)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  ISHIGAMI Akiko (60359916)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  NAKASONO Ichiro (30108287)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  塚 正彦 (00272956)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  堀 修
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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