MIZUNO Fumiko 水野文子

Researcher Number	70271202
Other IDs
Affiliation (based on the past Project Information) *help	2011 – 2019: 奈良県立医科大学, 医学部, 講師 2013: 奈良県立医科大学, 細菌学, 講師 2007: Nara Medical University, Bacteriology, Assistant Professor 2006: 奈良県立医科大学, 医学部, 助手 1999: 奈良県立医科大学, 医学部, 助手 1998 – 1999: 奈良県立医科大学, 細菌学教室, 助手 1995 – 1996: 奈良県立医科大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Urology / Bacteriology (including Mycology) Except Principal Investigator Bacteriology (including Mycology) / Sociology of education / Hygiene and public health / Public health/Health science / Respiratory organ internal medicine / Laboratory medicine
Keywords	Principal Investigator 病原性 / 動物モデル / キノロン耐性 / 大腸菌 / 動物実験モデル / 病原性因子 / 耐性獲得機序 / フルオロキノロン耐性 / ESBL産生大腸菌ST131株 / 非チフス … More / サルモネラ胃腸炎後 / サルモネラ脳症 / 非チフス性サルモネラ脳症 / L-form / 脳内ｻｲﾄｶｲﾝ / L form / マウスモデル / サルモネラ胃腸炎後脳症 … More Except Principal Investigator 腸管出血性大腸菌 / Gb3 / Shiga toxin / 低栄養 / ベロ毒素 / BCG / 大腸菌 / 男女医師間格差 / アカデミックキャリア / 男女共同参画 / ジェンダーと教育 / APOE4 / 低体重 / 認知機能 / 咀嚼力 / 歯の本数 / 多数歯欠損 / 歯周病 / 認知機能障害 / 高齢者 / apotosis / lipid raft / ghrelin / leptin / infection stress / shiga toxin-producing E. coli / アポトシス / 資質ラフト / グレリン / レプチン / 感染ストレス / vascular endothelial damage / encephalopathy / apoptosis / IL-10 / TNF-α / malnutrition / enterohemorrhagic E.coli / 血管内皮傷害 / 脳症 / アポトーシス / サイトカイン / cellular immunity / L forms / intracellular parasite / tuberculosis / 免疫維持機構 / in situ PCR / マクロファージ / 抗酸菌感染症 / 細胞性免疫 / L型菌 / 細胞内寄生菌 / 結核 / 遺伝子解析 / 大腸菌病原因子 / 新生児髄膜炎 / ゲノム解析 / 髄膜炎 / 病原因子 / 敗血症 / リポ蛋白 / 中性糖セラミド / HUS / 腸管感染症 / 志賀毒素 Less

ESBL産生大腸菌の動物実験モデルにおけるキノロン耐性獲得と病原性との関係Principal Investigator
- Principal Investigator
  
  水野文子
- Project Period (FY)
  2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Nara Medical University
The Developments of New Medical Education to Correct the Gender Gap in Academic Medicine
- Principal Investigator
  
  Suzaki Yasue
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Sociology of education
- Research Institution
  Nara Medical University
Association between periodontal disease and development of cognitive impairment in community-dwelling elderly people
- Principal Investigator
  
  Okamoto Nozomi
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hygiene and public health
- Research Institution
  Hyogo University of Teacher Education
  Nara Medical University
Elucidation of factors causing sepsis and establishment of prediction method by clinical analysis and molecular bacteriological approach
- Principal Investigator
  
  NAKAYAMA Akifumi
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Laboratory medicine
- Research Institution
  Gihu University of Medical Science
LDL-dependent cytotoxicity of Shiga toxin in the cells devoid of Gb3
- Principal Investigator
  
  KITA eiji
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Nara Medical University
Establish of a mouse model of encephalopathy after Salmonella gastroenteritisPrincipal Investigator
- Principal Investigator
  
  MIZUNO Fumiko
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Nara Medical University
Enhanced activation of Gb3-bound Shiga toxin by leptin induced after infection with STEC O157
- Principal Investigator
  
  KITA Eiji
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Nara Medical University
Analysis of the pathogenic mechanism of Shiga toxin-producing Escherichia coli infection for vaccine development
- Principal Investigator
  
  KITA Eiji
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Public health/Health science
- Research Institution
  Nara Medical University
Maintenance of acquired resistance to Mycobacterium tuberculosis by L form mycobacteria macrophages
- Principal Investigator
  
  KITA Eiji
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Nara Medical University

All 2017 2016 2015 2014 2013 2011 2008 2006

All Journal Article Presentation

[Journal Article] クラスA型β-ラクタマーゼ2015
- Author(s)
  1. 矢野寿一、中野竜一、中野章代、水野文子
- Journal Title
  
  臨床と微生物
  
  Volume: 42 Pages: 311-316
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670277
[Journal Article] Evaluation of the vitek 2 AST-N269 card for detection of meropenem resistance in imipenem-susceptible meropenem-resistant Enterobacteriaceae.2013
- Author(s)
  Koizumi A, Kasahara K, Komatsu Y, Ui K, Mizuno F, Nakayama A, Mikasa K.
- Journal Title
  
  J Clin Microbiol.
  
  Volume: 51 Issue: 11 Pages: 3908-3908
- DOI
  10.1128/jcm.02063-13
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670276, KAKENHI-PROJECT-25670277
[Journal Article] Selective induction of antimicrobial peptides from keratinocytes by staphylococcal bacteria.2013
- Author(s)
  Ommori R, Ouji N, Mizuno F, Kita E, Ikada Y, Asada H.
- Journal Title
  
  Microb Pathog.
  
  Volume: 56 Pages: 35-39
- DOI
  10.1016/j.micpath.2012.11.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590515, KAKENHI-PROJECT-23591650
[Journal Article] Enhanced expression of ABCA1 in non-rafts decreases the sensitivity of vascular endothelial cells to Shiga toxin2008
- Author(s)
  Mizuno F
- Journal Title
  
  Infect.Immun (in press)
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590434
[Journal Article] Enhanced expression of ABCA1 in non-rafts decreases the sensitivity of vascular endothelial cells to Shiga toxin2008
- Author(s)
  Mizuno F, Sugiura S, Kasahara K, Yasuda K, Kasahara K, Mikasa K, Kita, E
- Journal Title
  
  Infect. Immun (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590434
[Journal Article] Enhanced expression of ABCA1 in non-rafts decreases the sensitivity of vascularendothelial cells to Shiga toxin.2008
- Author(s)
  Mizuno F
- Journal Title
  
  Infect.Immun (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590434
[Presentation] 腸管外病原性大腸菌の病原遺伝子の保有状況について2017
- Author(s)
  中山章文、青木亮吾、平尾優太、宇野健司、今井雄一郎、水野文子、矢野寿一
- Organizer
  第28回日本臨床微生物学会
- Place of Presentation
  長崎
- Year and Date
  2017-01-21
- Data Source
  KAKENHI-PROJECT-25670277
[Presentation] 臨床検査技師と医師を対象にした多施設共同臨床微生物研修会の試み2016
- Author(s)
  2.李相太、笠原敬、水野文子、小泉章、宇井孝爾、阿部教行、福田砂織、口広智一、藤原美樹、市村佳彦、米倉久剛、山田幸司、近澤秀己、夏目聖子、矢野寿一、幸福知己、中村竜也
- Organizer
  第27回日本臨床微生物学会総会
- Place of Presentation
  東京
- Year and Date
  2016-01-31
- Data Source
  KAKENHI-PROJECT-25670277
[Presentation] Rapid identification of blaIMP-1 and blaIMP-6 by Multiplex ARMS PCR2016
- Author(s)
  Nakano A, Nakano R, Mizuno F, Endo S, Kasahara K, Yano H
- Organizer
  ASM Microbe
- Place of Presentation
  Boston, USA
- Year and Date
  2016-06-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25670277
[Presentation] 高速リアルタイムPCR装置を用いた結核菌迅速検出法の開発2015
- Author(s)
  中山章文、永井秀典、赤羽貴行、茂籠邦彦、水野文子
- Organizer
  第64回日本医学検査学会
- Place of Presentation
  福岡
- Year and Date
  2015-05-16
- Data Source
  KAKENHI-PROJECT-25670277
[Presentation] Analysis of pathogenic mechanism of Salmonella encephalopathy in mice2014
- Author(s)
  西川（水野）文子、東　伸岳、喜多英二
- Organizer
  第87回日本細菌学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25670277
[Presentation] 神経細胞でのABCA1発現低下と志賀毒素活性の変化2014
- Author(s)
  東伸岳、松村羊子、水野文子、喜多英二
- Organizer
  奈良県感染症研究会
- Place of Presentation
  奈良
- Year and Date
  2014-01-12
- Data Source
  KAKENHI-PROJECT-23590515
[Presentation] 臨床検査技師と医師を対象にした多施設共同臨床微生物研修会の試み2014
- Author(s)
  李相太、笠原敬、水野文子、小泉章、宇井孝爾、阿部教行、田平昭彦、口広智一、重田雅代、中山章文、藤原美樹、幸福知己、吉田弘之、福田砂織、中村竜也、市村佳彦、米倉久剛、山田幸司
- Organizer
  第25回日本臨床微生物学会総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-25670277
[Presentation] Analysis of pathogenic mechanism of Salmonella encephalopathy in mice2014
- Author(s)
  西川(水野)文子, 東伸岳, 喜多英二
- Organizer
  第87回日本細菌学会総会
- Place of Presentation
  東京都江戸川区船堀
- Year and Date
  2014-03-27
- Data Source
  KAKENHI-PROJECT-23659224
[Presentation] Analysis of　pathogenic mechanism of Salmonella encephalopathy in mice2014
- Author(s)
  西川（水野）文子、東伸岳、喜多英二
- Organizer
  日本細菌学会総会
- Place of Presentation
  東京都江戸川区船堀
- Data Source
  KAKENHI-PROJECT-23659224
[Presentation] LDL受容体を介する志賀毒素の取り込み2013
- Author(s)
  喜多英二、東伸岳、水野文子
- Organizer
  近畿感染症研究会
- Place of Presentation
  大阪
- Year and Date
  2013-06-17
- Data Source
  KAKENHI-PROJECT-23590515
[Presentation] Adjuvantivity of Salmonella polysomes2011
- Author(s)
  西川（水野）文子
- Organizer
  第84回日本細菌学会総会（IUMS2011)
- Place of Presentation
  北海道札幌市
- Data Source
  KAKENHI-PROJECT-23659224
[Presentation] 志賀毒素の受容体Gb3非発現細胞での毒性機序2011
- Author(s)
  喜多英二、松村羊子、東伸岳、水野文子
- Organizer
  近畿腸管感染症研究会
- Place of Presentation
  大阪
- Year and Date
  2011-06-18
- Data Source
  KAKENHI-PROJECT-23590515
[Presentation] Cellular factors involved in vascular damage by Shiga toxin2006
- Author(s)
  Okayama A, Higashi N, Mizuno F, Kita, E
- Organizer
  EHEC Symposium
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590434

1. KITA eiji (90133199)

# of Collaborated Projects: 4 results

# of Collaborated Products: 6 results
2. Okamoto Nozomi (70364057)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. Suzaki Yasue (30382302)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. SAGESHIMA Noriko (30398432)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. NAKAYAMA Akifumi (70536721)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
6. MATSUYOSHI hiroko (10448772)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 山本惠三 (90254490)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 車谷典男 (10124877)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 森川将行 (30305726)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 金子昇 (00397126)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 中野竜一 (80433712)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 御輿久美子 (20106503)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 笠原敬

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 王寺典子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

MIZUNO Fumiko 水野 文子

Research Projects

Research Products

Co-Researchers

ESBL産生大腸菌の動物実験モデルにおけるキノロン耐性獲得と病原性との関係Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The Developments of New Medical Education to Correct the Gender Gap in Academic Medicine

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Association between periodontal disease and development of cognitive impairment in community-dwelling elderly people

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of factors causing sepsis and establishment of prediction method by clinical analysis and molecular bacteriological approach

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

LDL-dependent cytotoxicity of Shiga toxin in the cells devoid of Gb3

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Establish of a mouse model of encephalopathy after Salmonella gastroenteritisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Enhanced activation of Gb3-bound Shiga toxin by leptin induced after infection with STEC O157

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of the pathogenic mechanism of Shiga toxin-producing Escherichia coli infection for vaccine development

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Maintenance of acquired resistance to Mycobacterium tuberculosis by L form mycobacteria macrophages

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] クラスA型β-ラクタマーゼ2015

Author(s)

Journal Title

Data Source

[Journal Article] Evaluation of the vitek 2 AST-N269 card for detection of meropenem resistance in imipenem-susceptible meropenem-resistant Enterobacteriaceae.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Selective induction of antimicrobial peptides from keratinocytes by staphylococcal bacteria.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Enhanced expression of ABCA1 in non-rafts decreases the sensitivity of vascular endothelial cells to Shiga toxin2008

Author(s)

Journal Title

Description

Data Source

[Journal Article] Enhanced expression of ABCA1 in non-rafts decreases the sensitivity of vascular endothelial cells to Shiga toxin2008

Author(s)

Journal Title

MIZUNO Fumiko 水野文子

[Presentation] Analysis of　pathogenic mechanism of Salmonella encephalopathy in mice2014