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Nagano Takashi  永野 隆

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NAGANO Takashi  永野 隆

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Researcher Number 70272854
Other IDs
Affiliation (based on the past Project Information) *help 2018 – 2021: 大阪大学, 蛋白質研究所, 招へい教授
2019: 大阪大学, 蛋白質研究所, 特任教授
2004: 福井大, 医学部, 助教授
2003: 福井大学, 医学部, 助教授
2002: Fukui Medical University, Faculty of Medicine, Associate Professor, 医学部, 助教授
1998 – 2001: 福井医科大学, 医学部, 助手
1996 – 1997: 新潟大学, 脳研究所, 助手
Review Section/Research Field
Principal Investigator
Neurochemistry/Neuropharmacology / Nerve anatomy/Neuropathology / Biological Sciences / General anatomy (including Histology/Embryology) / Nerve anatomy/Neuropathology / Basic Section 43010:Molecular biology-related / Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
Except Principal Investigator
Biological Sciences / Nerve anatomy/Neuropathology / Neurochemistry/Neuropharmacology / General anatomy (including Histology/Embryology) / General anatomy (including Histology/Embryology)
Keywords
Principal Investigator
大脳皮質 / 遺伝子クローニング / 神経科学 / 神経回路成熟 / 細胞移動 / 細胞生物学 / 脳室帯 / 染色分体 / クロマチン高次構造 / 1細胞解析 … More / エピジェネティクス / エピジェネティックス / シナプス蛋白 / CAG repeat / γ・グルタミルトランスペプチダーゼ / GAG repeat / γ-グルタミルトランスペプチダーゼ / Filamin 1 / 前後軸 / 部位差 / Filamin / インテグリン / SHIP-2 / 神経細胞 / フィラミン / 発生工学 / 遺伝子欠損マウス / Pancortin / 遺伝子改変マウス / 神経前駆細胞 / in utero electroporation / 細胞分裂 / 細胞分化 / Hi-C / RNA-seq / クロマチン / エピジェネティッゥス / 非対称細胞分裂 … More
Except Principal Investigator
アクチン / 細胞移動 / 細胞骨格 / 大脳皮質 / 神経上皮 / フィラミン / アクチン結合蛋白 / 葉状仮足 / 脳形成 / 脳室帯 / FRET / 視覚野 / ノックアウトマウス / 神経科学 / 発生・分化 / 脳・神経 / BDNF / Neurotransmitter / cytoskeleton / Filamin / actin binding protein / 電位 / 神経分化 / センサー / ニューロテンシン / 脳発達 / 部位特異的 / マウス / 膜電位 / 神経活動 / イメージング / GFP / Otx-1 / 錐体路 / 軸索消退 / 皮質橋路 / てんかん / 回路発達 / periventricular heterotopia / perirentricular heterotopia / フィラミン1 / フィラミンA / radial migration / 層形成 / カルパイン / アクチン結合蛋白質 / 領野 / 発達 / 転写因子 / GABA / シフト / 成長因子 / 神経栄養性因子 / 遺伝子破壊 / シナプス / 受容体 / 神経成長因子 / 可塑性 / ラジオイムノアッセイ / Growth Factor / Neurotropic / Gene Targetting / Knockout Mouse / Synapse / Receptor / 神経再生 / 抑制機構 / 中枢神経系 / フィルムモデル / 髄鞘関連糖蛋白質 / 重複傷害効果 / 分子軌道法 / ワーラー変性(MAG) / 最低空軌道(MAG) / グリア / 神経細胞 / 細胞内代謝 / 重複障害効果 / axonal regeneration / inhibition / central nervous system / optic nerve / film model / myelin-associated glycoprotein / conditioning lesion effect / molecular orbital calculations / ラメリポディア / 繊維状アクチン / アクチン繊維 / 転移 / 移動 / lamellipodia / actin / cell motility / lamellipodium / F-actin / calpain / 細胞内局在 / リン脂質 / Filmain / subcellular localization / polarity / cell migration / cerebral cortex / corticogenesis / エピゲノム / クロマチン / クロマチン高次構造 / 高次クロマチン / 非ゲノム情報複製 / 一細胞解析 / 細胞周期 / 非対称分裂 Less
  • Research Projects

    (23 results)
  • Research Products

    (19 results)
  • Co-Researchers

    (16 People)
  •  development of a new technology to detect epigenetic asymmetry between sister chromatids prior to cell divisionPrincipal Investigator

    • Principal Investigator
      Nagano Takashi
    • Project Period (FY)
      2019 – 2020
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
    • Research Institution
      Osaka University
  •  複製サイクルにおけるエピゲノム情報と高次クロマチン構造との連携の解明

    • Principal Investigator
      油谷 浩幸
    • Project Period (FY)
      2019 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  1細胞Hi-Cを用いた、G2期姉妹染色分体間の立体的関係の探索Principal Investigator

    • Principal Investigator
      永野 隆
    • Project Period (FY)
      2018 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Research Institution
      Osaka University
  •  a novel strategy toward chromatin dynamics based on precise single-cell informationPrincipal Investigator

    • Principal Investigator
      Nagano Takashi
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 43010:Molecular biology-related
    • Research Institution
      Osaka University
  •  大脳皮質脳室帯からの細胞移動の制御メカニズムについて

    • Principal Investigator
      佐藤 真
    • Project Period (FY)
      2003
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      福井医科大学
  •  アクチン結合蛋白フィラミンの分解による細胞移動調節とその分子基盤

    • Principal Investigator
      佐藤 真
    • Project Period (FY)
      2003
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      福井医科大学
  •  Otx1の大脳皮質形成に及ぼす役割と分子カスケードについて

    • Principal Investigator
      佐藤 真
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      University of Fukui
      福井医科大学
  •  大脳皮質脳室帯における接着結合を通じた細胞間シグナル伝達の解析Principal Investigator

    • Principal Investigator
      永野 隆
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Nerve anatomy/Neuropathology
    • Research Institution
      University of Fukui
      福井医科大学
  •  Cell biological studies on the mechanisms of directed migration toward the pial surface from the cortical ventricular zone

    • Principal Investigator
      SATO Makoto
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General anatomy (including Histology/Embryology)
    • Research Institution
      University of Fukui
      福井医科大学
  •  FILIPによる脳室帯からの細胞移動の制御メカニズムについて

    • Principal Investigator
      佐藤 真
    • Project Period (FY)
      2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      福井医科大学
  •  移動する神経細胞内でのFilamin-1依存性インテグリン・リサイクリングの解析Principal Investigator

    • Principal Investigator
      永野 隆
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      福井医科大学
  •  FILIPによる神経上皮からの細胞移動の制御メカニズムについて

    • Principal Investigator
      佐藤 真
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      福井医科大学
  •  細胞運動の調節に関わる新規細胞骨格関連因子の機能について

    • Principal Investigator
      佐藤 真
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      福井医科大学
  •  細胞内外に分かれて存在するPancortin蛋白群の機能と意義の解析Principal Investigator

    • Principal Investigator
      永野 隆
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      General anatomy (including Histology/Embryology)
    • Research Institution
      福井医科大学
  •  Otx-1の錐体路形成・成熟に及ぼす分子的基盤に関する研究

    • Principal Investigator
      佐藤 真
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Review Section
      Biological Sciences
    • Research Institution
      福井医科大学
  •  細胞運動の調節に関わる新規細胞骨格関連因子の機能について

    • Principal Investigator
      佐藤 真
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      福井医科大学
  •  A novel mechanism that controls frequency and stability of lamellipodium formation

    • Principal Investigator
      SATO Makoto
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General anatomy (including Histology/Embryology)
    • Research Institution
      Fukui Medical University
  •  大脳皮質内に部位差を形成する新たなメカニズムの発生工学的手法を用いた解析Principal Investigator

    • Principal Investigator
      永野 隆
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Nerve anatomy/Neuropathology
    • Research Institution
      福井医科大学
  •  神経分化・発達と神経活動との関連についての新しいアプローチによる研究

    • Principal Investigator
      SATO Makoto
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Nerve anatomy/Neuropathology
    • Research Institution
      福井医科大学
  •  Inhibition of axonal regeneration in the central nervous system

    • Principal Investigator
      TORIGOE Kojun
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Nerve anatomy/Neuropathology
    • Research Institution
      Fukui Medical University
  •  機能的神経回路形成・シナプス可塑性に関わる新規シナプス蛋白質の同定と機能解析Principal Investigator

    • Principal Investigator
      永野 隆
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      福井医科大学
      Niigata University
  •  神経回路形成に関わるラミニン様細胞外基質の同定と機能解析Principal Investigator

    • Principal Investigator
      永野 隆
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      Niigata University
  •  Intercelluar Bioactive Molecules in Neural Circuit

    • Principal Investigator
      NAWA Hiroyuki
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      NIIGATA UNIVERSITY

All 2021 2020 2019 2018 2004

All Journal Article Presentation Book

  • [Book] クロマチン解析実践プロトコール2020

    • Author(s)
      永野 隆(分担執筆)
    • Total Pages
      270
    • Publisher
      羊土社
    • ISBN
      9784758122481
    • Data Source
      KAKENHI-PROJECT-19K22392
  • [Book] クロマチン解析実践プロトコール2020

    • Author(s)
      永野隆
    • Total Pages
      270
    • Publisher
      羊土社
    • ISBN
      9784758122481
    • Data Source
      KAKENHI-PLANNED-19H05744
  • [Book] クロマチン解析実践プロトコール2020

    • Author(s)
      永野 隆(分担執筆)
    • Total Pages
      270
    • Publisher
      羊土社
    • ISBN
      9784758122481
    • Data Source
      KAKENHI-PROJECT-18H02374
  • [Journal Article] High-throughput preparation of improved single-cell Hi-C libraries using an automated liquid handling system2021

    • Author(s)
      Wing Leung and Takashi Nagano
    • Journal Title

      Methods in Molecular Biology

      Volume: -

    • Data Source
      KAKENHI-PROJECT-18H02374
  • [Journal Article] High-throughput preparation of improved single-cell Hi-C libraries using an automated liquid handling system.2021

    • Author(s)
      Wing Leung & Takashi Nagano
    • Journal Title

      Methods in Molecular Biology

      Volume: -

    • Data Source
      KAKENHI-PLANNED-19H05744
  • [Journal Article] High-throughput preparation of improved single-cell Hi-C libraries using an automated liquid handling system2021

    • Author(s)
      Wing Leung and Takashi Nagano
    • Journal Title

      Methods in Molecular Biology

      Volume: -

    • Data Source
      KAKENHI-PROJECT-19K22392
  • [Journal Article] Parental-to-embryo switch of chromosome organization in early embryogenesis2020

    • Author(s)
      Collombet Samuel、Ranisavljevic Noemie、Nagano Takashi、Varnai Csilla、Shisode Tarak、Leung Wing、Piolot Tristan、Galupa Rafael、Borensztein Maud、Servant Nicolas、Fraser Peter、Ancelin Katia、Heard Edith
    • Journal Title

      Nature

      Volume: 580 Pages: 142-146

    • DOI

      10.1038/s41586-020-2125-z

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K22392, KAKENHI-PUBLICLY-18H04714, KAKENHI-PLANNED-19H05744, KAKENHI-PROJECT-18H02374
  • [Journal Article] Genome organization and chromatin analysis identify transcriptional downregulation of insulin-like growth factor signaling as a hallmark of aging in developing B cells.2018

    • Author(s)
      Koohy H, Bolland DJ, Matheson LS, Schoenfelder S, Stellato C, Dimond A, Varnai C, Chovanec P, Chessa T, Denizot J, Manzano Garcia R, Wingett SW, Freire-Pritchett P, Nagano T, Hawkins P, Stephens L, Elderkin S, Spivakov M, Fraser P, Corcoran AE, Varga-Weisz PD.
    • Journal Title

      Genome Biology

      Volume: 19 Pages: 126-126

    • DOI

      10.1186/s13059-018-1489-y

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02374
  • [Journal Article] Filamin A and FILIP (Filamin A-interacting protein) regulate cell polarity and motility in neocortical subventricular and intermediate zones during radial migration.2004

    • Author(s)
      Nagano, T., Morikubo, S., Sato, M
    • Journal Title

      J.Neurosci. 24

      Pages: 9648-9657

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390054
  • [Journal Article] Filamin A and FILIP (Filamin A-interacting protein) regulate cell polarity and motility in neocortical subventricular and intermediate zones during radial migration.2004

    • Author(s)
      Nagano, T., Morikubo, S., Sato, M.
    • Journal Title

      Journal of Neuroscience 24

      Pages: 9648-9657

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390054
  • [Journal Article] Netrin-1 is crucial for the establishment of the dorsal column-medial lemniscal system2004

    • Author(s)
      Kubota C, Nagano T, Baba H, Sato M
    • Journal Title

      J.Neurochem. 89

      Pages: 1547-1554

    • Data Source
      KAKENHI-PROJECT-15029221
  • [Journal Article] Filamin A and FILIP (Filamin A-interacting protein) regulate cell polarity and motility in neocortical subventricular and intermediate zones during radial migration.2004

    • Author(s)
      Nagano, T., Morikubo, S., Sato, M.
    • Journal Title

      J.Neurosci. 24

      Pages: 9648-9657

    • Data Source
      KAKENHI-PROJECT-15390054
  • [Journal Article] Filamin A and FILIP (Filamin A-interacting protein) regulate cell polarity and motility in neocortical subventricular and intermediate zones during radial migration.2004

    • Author(s)
      Nagano, T., Morikubo, S., Sato, M.
    • Journal Title

      J.Neurosci. 24

      Pages: 9648-9657

    • Data Source
      KAKENHI-PROJECT-15029221
  • [Presentation] クロマチンの高次構造ダイナミクスと複製周期2019

    • Author(s)
      永野 隆
    • Organizer
      日本分子生物学会 第42回年会
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-18H04714
  • [Presentation] クロマチンの高次構造ダイナミクスと複製周期2019

    • Author(s)
      永野 隆
    • Organizer
      日本分子生物学会 第42回年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K22392
  • [Presentation] クロマチンの高次構造ダイナミクスと複製周期2019

    • Author(s)
      永野 隆
    • Organizer
      日本分子生物学会 第42回年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02374
  • [Presentation] クロマチンの高次構造ダイナミクスと複製周期2019

    • Author(s)
      永野隆
    • Organizer
      第42回日本分子生物学会 年会
    • Invited
    • Data Source
      KAKENHI-PLANNED-19H05744
  • [Presentation] 姉妹染色分体を鑑別可能なHi-C技術開発の試み2018

    • Author(s)
      永野 隆
    • Organizer
      日本生化学会第91回大会
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-18H04714
  • [Presentation] 1細胞レベルで見直した分裂間期マウスES細胞のクロマチン高次構造2018

    • Author(s)
      永野 隆
    • Organizer
      第12回日本エピジェネティクス研究会年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02374
  • 1.  SATO Makoto (10222019)
    # of Collaborated Projects: 14 results
    # of Collaborated Products: 5 results
  • 2.  YAGI Hideshi (10303372)
    # of Collaborated Projects: 13 results
    # of Collaborated Products: 0 results
  • 3.  安藤 康一 (70334810)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  NAWA Hiroyuki (50183083)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  SAITO Mako (50283023)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  OTSU Yo (40277504)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  SHIBUKI Katsuei (40146163)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  TORIGOE Kojun (50126603)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  油谷 浩幸 (10202657)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  熊 化保
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  HUABAO Xiong
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  SILVA Alcino
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  堀川 洋
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  CLINE Holly
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  ENIKOLOPOV G
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  YI Zhong
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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