KOBATA Kenji 古旗賢二

… Alternative Names

古旗賢二コバタケンジ

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Researcher Number	70275105
Other IDs
External Links
Affiliation (Current)	2025: 城西大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2021 – 2025: 城西大学, 薬学部, 教授 2007 – 2011: Josai University, 薬学部, 准教授 2003 – 2005: 静岡県立大学, 食品栄養科学部, 助手 2000 – 2001: 静岡県立大学, 食品栄養科学部, 助手
Review Section/Research Field	Principal Investigator Basic Section 38050:Food sciences-related / Food science / Bioproduction chemistry/Bioorganic chemistry / 食品科学・栄養科学 Except Principal Investigator Basic Section 39030:Horticultural science-related / Food science / Eating habits, studies on eating habits
Keywords	Principal Investigator カプサイシン / カプシエイト / 酸化ストレス耐性 / 微量分析 / コーヒー / ピロカテコール / 脂質 / 植物 / トリアシルグリセリド / 植物油 … More / バニリルアミン / 無辛味類縁体 / トウガラシ / 食品 / カプシコニエイト / アシルトランスフェラー / アシルトランスフェラーゼ / カプサイシン合成酵素 / MS / LC-MS / 安定同位体 / 生合成 / リパーゼ / 酵素的合成 / エネルギー代謝亢進 / バニリン酸 / バニリルアルコール / 体内動態 / リバーゼ / 酵素合成 / アドレナリン分泌 / 体熱産生 / カプシノイド … More Except Principal Investigator カプサイシン / TRPV1 / 遺伝子組換え / ナス科 / トウガラシ / capsaicin / 成分育種 / ゲノム / 遺伝子組み換え / capsaicinol / Sanshool / TRP familly / olvanilate / shogaol / gingerol / intracellular Ca^<2+> concentration / サンショオール / 細胞内Ca2+濃度 / TRPファミリー / オルバニレイト / ショウガオール / ジンゲロール / 細胞内Ca^<2+>濃度 / determination / extraction / stability / cooking / capsiate / カレー / 油系 / 水系 / カプシノイド / 定量 / 抽出 / 安定性 / 調理 / カプシエイト / TRP受容体 / 生理活性 / 内蔵脂肪 / エネルギー代謝 / TRPA1 / 食品成分 Less

トウガラシ果実に特異的なカプサイシン生合成の分子基盤と種・部位を超越した成分育種
- Principal Investigator
  
  田中義行
- Project Period (FY)
  2025 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 39030:Horticultural science-related
- Research Institution
  Kyoto University
Development of a biological sample analysis method for pyrocatechol produced during coffee roasting and verification of the hormesis effect of pyrocatecholPrincipal Investigator
- Principal Investigator
  
  古旗賢二
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38050:Food sciences-related
- Research Institution
  Josai University
トウガラシにおけるカプサイシン生合成の種・組織特異性の打破と成分育種展開
- Principal Investigator
  
  田中義行
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 39030:Horticultural science-related
- Research Institution
  Kyoto University
Long chain N-vanillyl-acylamides from capsicum oleoresinPrincipal Investigator
- Principal Investigator
  
  KOBATAKE Kenji
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Food science
- Research Institution
  Josai University
Study on the biosynthesis pathway of novel Capsicum compound, capsiate, and the factor for the development of pungency in Capsicum plants.Principal Investigator
- Principal Investigator
  
  KOBATA Kenji
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bioproduction chemistry/Bioorganic chemistry
- Research Institution
  Josai University
Food components activating thermosensitive TRP receptors and their effects to energy metabolism
- Principal Investigator
  
  WATANABE Tatuo
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Food science
- Research Institution
  University of Shizuoka
Investigation of Functional Ingredients in Vegetables that Increase Body Temperature, and Analysis of Its Function via Neuronal System.
- Principal Investigator
  
  MORITA Akihito
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Food science
- Research Institution
  University of Shizuoka
Measurement of changes of pungency-related compounds in pepper under cooking and development of stabilization method
- Principal Investigator
  
  WATANABE Tatsuo
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Eating habits, studies on eating habits
- Research Institution
  University of Shizuoka
カプシノイドのアドレナリン分泌活性による体熱産生効果の評価と、酵素的合成法の確立Principal Investigator
- Principal Investigator
  
  古旗賢二
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  食品科学・栄養科学
- Research Institution
  University of Shizuoka

All 2023 2022 2021 2011 2010 2009 2008 2007 2006 2005

All Journal Article Presentation Book

[Book] スパイス・ハーブの機能と最新応用技術第10章 3.カプシノイドとその他の成分の機能2011
- Author(s)
  古旗賢二
- Publisher
  シーエムシー出版
- Data Source
  KAKENHI-PROJECT-21580152
[Book] スパイス・ハーブの機能と最新応用技術2011
- Author(s)
  古旗賢二
- Publisher
  シーエムシー出版
- Data Source
  KAKENHI-PROJECT-21580152
[Book] Food components activating capsaicin receptor TRPV1, in "Nutrigenomics and Proteomics in Health and Disease: Food Factors and Gene Interactions. " (Mine Y, Miyashita K, Shahidi F)2009
- Author(s)
  Watanabe T, Iwasaki Y, Morita A, Kobata K
- Publisher
  Wiley-Blackwell
- Data Source
  KAKENHI-PROJECT-19580146
[Journal Article] Biochemical Aspects of Putative Aminotransferase Responsible for Converting Vanillin to Vanillylamine in the Capsaicinoid Biosynthesis Pathway in Capsicum Plants2023
- Author(s)
  Nakaniwa Ryota、Misawa Yuki、Nakasato Saika、Sano Kaori、Tanaka Yoshiyuki、Nakatani Sachie、Kobata Kenji
- Journal Title
  
  Journal of Agricultural and Food Chemistry
  
  Volume: 72 Issue: 1 Pages: 559-565
- DOI
  10.1021/acs.jafc.3c07369
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K21193
[Journal Article] A single amino acid substitution alters the vanillylamine synthesis activity of Capsicum pAMT2023
- Author(s)
  Sano Kaori、Nakasato Saika、Nagata Koji、Kobata Kenji
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 680 Pages: 86-92
- DOI
  10.1016/j.bbrc.2023.09.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K21193
[Journal Article] An evolutionary view of vanillylamine synthase pAMT, a key enzyme of capsaicinoid biosynthesis pathway in chili pepper2023
- Author(s)
  Kusaka Hirokazu、Nakasato Saika、Sano Kaori、Kobata Kenji、Ohno Sho、Doi Motoaki、Tanaka Yoshiyuki
- Journal Title
  
  The Plant Journal
  
  Volume: 117 Issue: 5 Pages: 1453-1465
- DOI
  10.1111/tpj.16573
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K21193
[Journal Article] Vanillin reduction in the biosynthetic pathway of capsiate, a non-pungent component of Capsicum fruits, is catalyzed by cinnamyl alcohol dehydrogenase2022
- Author(s)
  Sano Kaori、Uzawa Yuya、Kaneshima Itsuki、Nakasato Saika、Hashimoto Masashi、Tanaka Yoshiyuki、Nakatani Sachie、Kobata Kenji
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 12384-12384
- DOI
  10.1038/s41598-022-16150-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K21193
[Journal Article] Long-chain N-vanillyl-acylamides from Capsicum oleoresin2010
- Author(s)
  Kenji Kobata, Kazumi Saito, Hitomi Tate, Aki Nashimoto, Hiromi Okuda, Ikue Takemura, Ken Miyakawa, Masayoshi Takahashi, Kazuo Iwai, and Tatsuo Watanab
- Journal Title
  
  Journal of Agricultural and Food Chemistry
  
  Volume: 58(6) Pages: 3627-3631
- NAID
  120005746416
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21580152
[Journal Article] Long-Chain N-Vanillyl-acylamides from Capsicum Oleoresin2010
- Author(s)
  Kenji Kobata
- Journal Title
  
  Journal of Agricultural and Food Chemistry 58
  
  Pages: 3627-3631
- NAID
  120005746416
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21580152
[Journal Article] Isolation of coniferyl esters from Capsicum baccatum L., and theirenzymatic preparation and agonist activity for TRPV1.2008
- Author(s)
  K. Kobata, H. Tate, Y. Iwasaki, Y. Tanaka, K. Ohtsu, S. Yazawa, and T. Watanabe.
- Journal Title
  
  Phytochemistry 6 9(5)
  
  Pages: 1179-1184
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19580125
[Journal Article] Isolation of coniferyl esters from Capsicum baccatum L.,and their enzymatic preparation and agonist activity for TRPV12008
- Author(s)
  Kobata, K.
- Journal Title
  
  Phytochemistry 69
  
  Pages: 1179-1184
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19580125
[Journal Article] Synthesis by allylic oxidation and its effect on TRPV1-expressing cells and adrenaline secretion in rats.2006
- Author(s)
  Kobata,K., et al.
- Journal Title
  
  Biosci. Biotech. Biochem. 70
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16580105
[Journal Article] A nonpungent component of steamed ginger-[10]-shogaol-increases adrenaline secretion via the activation of TRPV 12006
- Author(s)
  Iwasaki, Y., Morita, A., Iwasawa, T., Kobata, K., Sekiwa, Y., Morimitsu, Y., Kubota, K., Watanabe, T.
- Journal Title
  
  Nutritinoal Neurosciences 9
  
  Pages: 169-178
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16580105
[Journal Article] Lipophilicity of capsaicinoids and capsinoids influences the multiple activation process of rat TRPV12006
- Author(s)
  Morita, A., Iwasaki, Y., Kobata, K., Iida, T., Higashi, T., Oda, K., Suzuki, A., Narukawa, M., Sasakuma, S., Yokogoshi, H., Yazawa, S., Tominaga, M., Watanabe, T.
- Journal Title
  
  Life Sciences 79
  
  Pages: 2303-2310
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16580105
[Journal Article] Capsaicinol : Synthesis by allylic oxidation and its effect on TRPV1-expressing cells and adrenaline secretion in rats2006
- Author(s)
  Kobata, K., Iwasawa, T., Iwasaki, Y., Morita, A., Suzuki, Y., Kikuzaki, H., Nakatani, N., Watanabe, T.
- Journal Title
  
  Biosci.Biotechnol.Biochem. 70(8)
  
  Pages: 1904-1912
- NAID
  10018528146
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16580105
[Journal Article] On the Functionality of Olvanil, a Capsaicin Analog of No or Very Low Pungency2005
- Author(s)
  Watanabe, T., Kobata, K., Morita, A., Iwasaki, Y.
- Journal Title
  
  Foods & Food Ingredients Journal of Japan 210(No.3)
  
  Pages: 214-221
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16580105
[Journal Article] Food Ingredients Activating TRPV1, a receptor of casaicin2005
- Author(s)
  Iwasaki, Y., Morita.A., Kobata, K., Sugai, E., Morimitsu, Y., Kubota, K., Watanabe, T.
- Journal Title
  
  Pharmacometrics(Japan) 69
  
  Pages: 18-20
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16580105
[Presentation] Evolutionary characterization and enzymatic activities of pAMT homologs provide an insight into origin of vanillylamine synthesis in the capsaicinoid biosynthesis pathway of chili peppers2023
- Author(s)
  Tanaka Yoshiyuki、Kusaka Hirokazu、Nakasato Saika、Sano Kaori、Kobata Kenji、Ohno Sho、Doi Motoaki
- Organizer
  第4回アジア園芸学会議（AHC2023）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21193
[Presentation] カプサイシン生合成における推定アミノトランスフェラーゼの特性に関する研究（第2報）2023
- Author(s)
  中庭亮太，佐野香織，三澤悠貴，中里彩夏，中谷祥恵，古旗賢二．
- Organizer
  日本農芸化学会2023年度大会
- Data Source
  KAKENHI-PROJECT-23K21193
[Presentation] ナス科植物 GABA-Ts の系統関係が示すトウガラシのバニリルアミン合成遺伝子pAMTの起源2023
- Author(s)
  日下宏和・中里彩夏・佐野香織・古旗賢二・大野翔・土井元章・田中義行
- Organizer
  園芸学会　令和5年度春季大会
- Data Source
  KAKENHI-PROJECT-23K21193
[Presentation] カプシエイト生合成におけるシンナミルアルコールデヒドロゲナーゼの関与2022
- Author(s)
  大野翔太朗，佐野香織，橋本雅司，中谷祥恵，古旗賢二
- Organizer
  日本農芸化学会2022年度大会
- Data Source
  KAKENHI-PROJECT-23K21193
[Presentation] トウガラシのバニリルアミン合成遺伝子pAMTとナス科植物オーソログの系統関係および酵素活性.2022
- Author(s)
  日下宏和・中里彩夏・佐野香織・古旗賢二・大野　翔・土井元章・田中義行
- Organizer
  令和4年度園芸学会春季大会
- Data Source
  KAKENHI-PROJECT-23K21193
[Presentation] 1残基のアミノ酸置換がもたらすハバネロと夢祭りのpAMT酵素活性の違い2022
- Author(s)
  中里彩夏，佐野香織，古旗賢二
- Organizer
  日本農芸化学会2022年度大会
- Data Source
  KAKENHI-PROJECT-23K21193
[Presentation] トウガラシの種間におけるカプサイシン合成効率の違い．2021
- Author(s)
  中里彩夏，古旗賢二，田中義行，佐野香織
- Organizer
  第6回ユニーク会
- Data Source
  KAKENHI-PROJECT-23K21193
[Presentation] Long chain N-vanillyl-acylamides from Capsicum oleoresin2011
- Author(s)
  Kenli Kobata, Kazumi Saito, Hitomi Tate, Aki Nashimoto, Hiromi Okuda, Ikue Takemura, Ken Miyakawa, Masayoshi Takahashi, Kazuo Iwai, and Tatsuo Watanabe
- Organizer
  International Conference and Exhibition on Nutraceuticals and Functional Foods 2011
- Place of Presentation
  札幌
- Year and Date
  2011-11-15
- Data Source
  KAKENHI-PROJECT-21580152
[Presentation] トウガラシオレオレジンに含まれる長鎖N-バニリルアシルアミド類(LCNVAs)2010
- Author(s)
  古旗賢二, 齋藤和美, 楯人美, 梨本亜紀, 奥田祐美, 竹村郁恵, 宮川健, 高橋和良, 岩井和夫, 渡辺達夫
- Organizer
  日本農芸化学会2010年度大会
- Place of Presentation
  東京
- Year and Date
  2010-03-28
- Data Source
  KAKENHI-PROJECT-21580152
[Presentation] トウガラシオレオレジンに含まれる長鎖N-バニリルアシルアミド類(LCNVAs)2010
- Author(s)
  古旗賢二
- Organizer
  日本農芸化学会
- Place of Presentation
  東京大学駒場キャンパス
- Year and Date
  2010-03-28
- Data Source
  KAKENHI-PROJECT-21580152
[Presentation] 長鎖N-バニリルアシルアミド類はトウガラシオレオレジン中に含まれる2010
- Author(s)
  久保田佳織, 斉藤和美, 楯人美, 梨本亜希, 奥田裕美, 竹村育恵, 宮川健, 坂田充紀, 高橋和良, 古旗賢二, 岩井和夫, 渡辺達夫
- Organizer
  第25回日本香辛料研究会
- Place of Presentation
  静岡
- Year and Date
  2010-11-12
- Data Source
  KAKENHI-PROJECT-21580152
[Presentation] Monoacylglycerols activate transient receptor potential vanilloid 1 (TRPV1).2008
- Author(s)
  Iwasaki Y, Saito O, Tanabe M, Inayoshi K, Kobata K, Uno S, Morita A, Watatanabe T
- Organizer
  Neuroscience 2008
- Place of Presentation
  Washington DC (USA)
- Data Source
  KAKENHI-PROJECT-19580146
[Presentation] Monoacylglycerolsのカプサイシン受容体TRPV1への作用.2008
- Author(s)
  岩崎有作, 斉藤織音, 田辺学, 古旗賢二, 守田昭仁, 渡辺達夫
- Organizer
  日本農芸化学会2008年度(平成20年度)大会
- Place of Presentation
  名古屋市
- Data Source
  KAKENHI-PROJECT-19580146
[Presentation] カプサイシン受容体に作用する食品成分の探索.2007
- Author(s)
  岩崎有作, 田辺学, 斉藤織音, 宇野秀一, 古旗賢二, 守田昭仁, 渡辺達夫
- Organizer
  第61回日本栄養・食糧学会大会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19580146
[Presentation] 食品中のカプサイシン受容体TRPV1を活性化する成分.2007
- Author(s)
  渡辺達夫, 岩崎有作, 古旗賢二, 守田昭仁
- Organizer
  第2回食品薬学シンポジウム
- Place of Presentation
  静岡市
- Data Source
  KAKENHI-PROJECT-19580146
[Presentation] トウガラシ辛味関連化合物生合成に関わる酵素のLS/MS/MSを用いた活性測定系の構築2007
- Author(s)
  古旗賢二
- Organizer
  日本香辛料研究会
- Place of Presentation
  お茶の水女子大学
- Year and Date
  2007-09-22
- Data Source
  KAKENHI-PROJECT-19580125
[Presentation] 小麦のmonoacylglycerolはTRPV1を活性化する.2007
- Author(s)
  岩崎有作, 斉藤織音, 田辺学, 古旗賢二, 守田昭仁, 渡辺達夫
- Organizer
  第3回体温調節、温度受容研究会
- Place of Presentation
  愛知県岡崎市
- Data Source
  KAKENHI-PROJECT-19580146
[Presentation] トウガラシ辛味関連化合物生合成に関わる酵素のLS/MS/MS を用いた活性測定系の構築2007
- Author(s)
  三村真琴,菅原舞,古旗賢二,矢澤進,渡辺達夫
- Organizer
  第22 回日本香辛料研究会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19580125
[Presentation] 食品中のmonoacylglycerolsはカプサイシン受容体TRPV1を活性化させる.2007
- Author(s)
  岩崎有作, 斉藤織音, 田辺学, 古旗賢二, 守田昭仁, 渡辺達夫
- Organizer
  第22回日本香辛料研究会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19580146
[Presentation] カプサイシン受容体TRPV1を活性化する食品成分2007
- Author(s)
  渡辺達夫, 岩崎有作, 守田昭仁, 古旗賢二
- Organizer
  日本動物細胞工学会2007年度大会
- Place of Presentation
  高崎
- Data Source
  KAKENHI-PROJECT-19580146

1. WATANABE Tatuo (10210915)

# of Collaborated Projects: 3 results

# of Collaborated Products: 12 results
2. MORITA Akihito (40239653)

# of Collaborated Projects: 2 results

# of Collaborated Products: 13 results
3. 田中義行 (20704480)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
4. 大野翔 (10722001)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
5. 杉山立志 (30377270)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 佐野香織 (70612092)

# of Collaborated Projects: 2 results

# of Collaborated Products: 11 results
7. NARUKAWA Masataka (50432349)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. KAINUMA Yasuko (90071000)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

KOBATA Kenji 古旗 賢二

古旗 賢二 コバタ ケンジ

Research Projects

Research Products

Co-Researchers

トウガラシ果実に特異的なカプサイシン生合成の分子基盤と種・部位を超越した成分育種

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of a biological sample analysis method for pyrocatechol produced during coffee roasting and verification of the hormesis effect of pyrocatecholPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

トウガラシにおけるカプサイシン生合成の種・組織特異性の打破と成分育種展開

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Long chain N-vanillyl-acylamides from capsicum oleoresinPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study on the biosynthesis pathway of novel Capsicum compound, capsiate, and the factor for the development of pungency in Capsicum plants.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

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Food components activating thermosensitive TRP receptors and their effects to energy metabolism

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Investigation of Functional Ingredients in Vegetables that Increase Body Temperature, and Analysis of Its Function via Neuronal System.

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Measurement of changes of pungency-related compounds in pepper under cooking and development of stabilization method

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カプシノイドのアドレナリン分泌活性による体熱産生効果の評価と、酵素的合成法の確立Principal Investigator

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[Book] スパイス・ハーブの機能と最新応用技術 第10章 3.カプシノイドとその他の成分の機能2011

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[Book] スパイス・ハーブの機能と最新応用技術2011

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[Book] Food components activating capsaicin receptor TRPV1, in "Nutrigenomics and Proteomics in Health and Disease: Food Factors and Gene Interactions. " (Mine Y, Miyashita K, Shahidi F)2009

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[Journal Article] Biochemical Aspects of Putative Aminotransferase Responsible for Converting Vanillin to Vanillylamine in the Capsaicinoid Biosynthesis Pathway in Capsicum Plants2023

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[Journal Article] A single amino acid substitution alters the vanillylamine synthesis activity of Capsicum pAMT2023

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KOBATA Kenji 古旗賢二

古旗賢二コバタケンジ

[Book] スパイス・ハーブの機能と最新応用技術第10章 3.カプシノイドとその他の成分の機能2011