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NAKAJIMA Hiroo  中嶋 啓雄

ORCIDConnect your ORCID iD *help
… Alternative Names

中嶋 哲雄  ナカジマ ヒロオ

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Researcher Number 70275212
Other IDs
External Links
Affiliation (based on the past Project Information) *help 2009: 京都府立医大, 医学系研, 講師
2003 – 2004: 京都府立医科大学, 医学研究科, 講師
2003: Kyoto Prefectural University of Medicine, Surgery, Assistant professor, 医学研究科, 助手
1995 – 2002: 京都府立医科大学, 医学部, 助手
1998 – 2000: 京都府立医科大学, 第2外科, 助手
Review Section/Research Field
Principal Investigator
General surgery / General surgery
Except Principal Investigator
General surgery / Anesthesiology/Resuscitation studies / General surgery / Thoracic surgery / Digestive surgery
Keywords
Principal Investigator
アポトーシス / mitochondria / apoptosis / breast cancer / Tetrocarcin A / ADCC / Bcl-2 / Fas-Ligand / Xenotransplantation / ヒト乳癌 … More / カスパーゼ / 抗癌剤耐性 / DXR / NK cell / Apoptosis / Fas Ligand / Fas / 異種細胞傷害 / 異種移植 / BCL-2 / ICE(=IL-I converting enzyne) / グランザイム / パ-フォリン / Fas-ligand(=CD95L) / Fas antigen(=CD95) / 免疫抑制 / 臓器移植 / Apopain / ICE / 急性拒絶反応 / 心移植 / 免疫抑制剤 / カスパーゼ(Caspase) / アポトーシス(Apoptosis) … More
Except Principal Investigator
アポトーシス / Fas / FasL / FTY720 / mitochondria / Fra-1 / AP-1 / apoptosis / breast cancer / ascochlorin / HMGB1 / Apoptosis / Acute lung injury / ARDS / loxP / Cre / CTLA4Ig / CrmA / CVF (Cobra Venom Factor) / perforin / アポトーシス(Apoptosis) / ヒト乳癌 / 抗癌剤抵抗性 / エストロゲン感受性 / Acute respiratory distress syndrome / HMG-1 / 急性呼吸窮迫症候群ARDS / 急性呼吸窮迫症候群(ARDS) / 急性肺障害 / 急性肺損傷 / heart transplantation / liver transplantation / adenovirus vector / 免疫貴容 / 遺伝子導入 / cre I lox P / HVJ-リポゾーム / アデノウィルスベクター / Fash / Cre-loxP system / caspase / 拒絶反応 / CD28 / B7.2 / 相乗的免疫抑制効果 / 共刺激分子 / ラット / 心移植 / 肝移植 / アデノウイルスベクター / Lymphokines / Immunosuppressive drug / Local therapy / Immune tolerance / Organ Transplantation / 腎移植 / 選択的免疫抑制 / FK506 / 犬腎移植 / モノクローナル抗体 / 局所選択的免疫抑制 / 臓器移植 / granzyme / NK cell / delayd xenograft rejection / xenotransplantation / CVF / AT-III / sCR1 / discordant異種移植 / 遅延型異移拒絶反応 / CVF(Cobra venomfactor) / グランザイム / パ-フォリン / NK細胞 / 遅延型異種拒絶反応 / 異種移植 / granzymeB / Fas Ligand / 動脈硬化 / 血管移植 / Bcl-2分子 / グランザイム(granzymes) / パーフォリン(perforin) / Fas分子 / Fas-Ligand / 細胞骨格 / PARP / アクチン(Actin tilament) / 細胞周期 / カスパーゼ(Caspase) / Fas システム / 遺伝子治療 / 免疫療法 / Fas Lシステム / 抗腫瘍免疫応答 Less
  • Research Projects

    (13 results)
  • Research Products

    (3 results)
  • Co-Researchers

    (19 People)
  •  トリプルネガティブ乳癌を標的とした新規薬物療法の開発Principal Investigator

    • Principal Investigator
      中嶋 啓雄
    • Project Period (FY)
      2009
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  A Novel Target Molecule Therapy for Breast Cancer using Tetrocarcin A(TC-A)Principal Investigator

    • Principal Investigator
      NAKAJIMA Hiroo
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Development and Analysis of a Novel Agent of Ascochlorin(ASC) on Estrogen Receptors(ER)-Negative Breast Cancer

    • Principal Investigator
      SAWAI Kiyoshi
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Apoptosis and inflammatory cell in the pathogenesis of acute lung injury

    • Principal Investigator
      HASHIMOTO Satoru
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  アポトーシスを誘導する新規免疫調節物質の分子生物学的免疫抑制機序の解析

    • Principal Investigator
      岡 隆宏
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General surgery
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  凍結保存血管の移植後動脈硬化性病変に対する分子生物学的制御法の開発

    • Principal Investigator
      和田 行雄
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Thoracic surgery
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Induction of transplantation tolerance based on bio-molecular technique

    • Principal Investigator
      SUZUKI Seiichi
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (A).
    • Research Field
      General surgery
    • Research Institution
      National Children's Medical Research Center
  •  Analysis of the molecular mechanism of DXR and the therapeutic methodPrincipal Investigator

    • Principal Investigator
      NAKAJIMA Hiroo
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General surgery
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  APOPTOSIS IN ACUTE LUNG INJURY

    • Principal Investigator
      HASHIMOTO Satoru
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      KYOTO PREFECTURAL UNIVERSITY OF MEDICINE
  •  アポトーシス誘導分子Fasを標的とした癌の免疫療法

    • Principal Investigator
      山岸 久一
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Digestive surgery
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  アポトーシス誘導分子の制御による特異的免疫抑制療法の開発Principal Investigator

    • Principal Investigator
      中嶋 啓雄
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      General surgery
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  The development of local immunosuppression in organ transplantation

    • Principal Investigator
      YOSHIMURA Norio
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Research about mechanism of delayd xenograft rejection (DXR).

    • Principal Investigator
      OKA Takahiro
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General surgery
    • Research Institution
      Kyoto Prefectural University of Medicine

All 2005 2004

All Journal Article

  • [Journal Article] Selective cytotoxicity of ascochlorin in ER-negative human breast cancer cell lines.2005

    • Author(s)
      Sakaguchi, K., Nakajima, H., Mizuta, N., et al.
    • Journal Title

      Biochem Biophys Res Commun 329

      Pages: 46-50

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15591352
  • [Journal Article] Selective cytotoxicity of ascochlorin in ER-negative human breast cancer cell lines.2005

    • Author(s)
      Sakaguchi, K, Nakajima, H., Mizuta, N., et al.
    • Journal Title

      Biochem Biophys Res Commun 329

      Pages: 46-50

    • Data Source
      KAKENHI-PROJECT-15591352
  • [Journal Article] Characterization of 4-O-methyl-ascochlorin-induced apoptosis in comparison with typical apoptotic inducers in human leukemia cell lines2004

    • Author(s)
      Tsuruga, M., Nakajima, H., et al.
    • Journal Title

      Apoptosis 9

      Pages: 429-435

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15591351
  • 1.  OKA Takahiro (60079837)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 2.  YOSHIMURA Norio (00191643)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 3.  SUZUKI Seiichi (00111386)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  HASHIMOTO Satoru (90167578)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  SAWAI Kiyoshi (80192102)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  RII Kou (60321890)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  KIMURA Hiromitsu (80115477)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  ENOSAWA Shin (40232962)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  SHINOMIYA Takahisa (30196414)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  SHIME Nobuaki (00260795)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  ONODERA Hideki (50204269)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  MATAUDA Tomoyuki (30281265)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  山岸 久一 (40128723)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  和田 行雄 (90167213)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  岡本 雅彦 (90295650)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  濱島 高志 (00238065)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  今西 二郎 (40112510)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  小林 敦子 (70264778)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  田村 明彦
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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