NAKAJIMA Hiroo 中嶋啓雄

… Alternative Names

Researcher Number	70275212
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2009: 京都府立医大, 医学系研, 講師 2003 – 2004: 京都府立医科大学, 医学研究科, 講師 2003: Kyoto Prefectural University of Medicine, Surgery, Assistant professor, 医学研究科, 助手 1995 – 2002: 京都府立医科大学, 医学部, 助手 1998 – 2000: 京都府立医科大学, 第2外科, 助手
Review Section/Research Field	Principal Investigator General surgery / General surgery Except Principal Investigator General surgery / Anesthesiology/Resuscitation studies / Digestive surgery / Thoracic surgery / General surgery
Keywords	Principal Investigator アポトーシス / Xenotransplantation / Fas-Ligand / Bcl-2 / ADCC / Tetrocarcin A / breast cancer / apoptosis / mitochondria / アポトーシス(Apoptosis) … More Except Principal Investigator アポトーシス / Fas / FasL / FTY720 / アポトーシス(Apoptosis) / perforin / CVF (Cobra Venom Factor) / CrmA / CTLA4Ig / Cre / loxP / ARDS / Acute lung injury / Apoptosis / HMGB1 / ascochlorin / breast cancer / apoptosis / AP-1 / Fra-1 / mitochondria / 抗腫瘍免疫応答 / Fas Lシステム / 免疫療法 / 遺伝子治療 / Fas システム / カスパーゼ(Caspase) / 細胞周期 / アクチン(Actin tilament) / PARP / 細胞骨格 / Fas-Ligand / Fas分子 / パーフォリン(perforin) / グランザイム(granzymes) / Bcl-2分子 / 血管移植 / 動脈硬化 / Fas Ligand / granzymeB / 異種移植 / 遅延型異種拒絶反応 / NK細胞 / パ-フォリン / グランザイム / CVF(Cobra venomfactor) / 遅延型異移拒絶反応 / discordant異種移植 / sCR1 / AT-III / CVF / xenotransplantation / delayd xenograft rejection / NK cell / granzyme / 臓器移植 / 局所選択的免疫抑制 / モノクローナル抗体 / 犬腎移植 / FK506 / 選択的免疫抑制 / 腎移植 / Organ Transplantation / Immune tolerance / Local therapy / Immunosuppressive drug / Lymphokines / アデノウイルスベクター / 肝移植 / 心移植 / ラット / 共刺激分子 / 相乗的免疫抑制効果 / B7.2 / CD28 / 拒絶反応 / caspase / Cre-loxP system / Fash / アデノウィルスベクター / HVJ-リポゾーム / cre I lox P / 遺伝子導入 / 免疫貴容 / adenovirus vector / liver transplantation / heart transplantation / 急性肺損傷 / 急性肺障害 / 急性呼吸窮迫症候群(ARDS) / 急性呼吸窮迫症候群ARDS / HMG-1 / Acute respiratory distress syndrome / エストロゲン感受性 / 抗癌剤抵抗性 / ヒト乳癌 Less

トリプルネガティブ乳癌を標的とした新規薬物療法の開発Principal Investigator
- Principal Investigator
  
  中嶋啓雄
- Project Period (FY)
  2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Kyoto Prefectural University of Medicine
A Novel Target Molecule Therapy for Breast Cancer using Tetrocarcin A(TC-A)Principal Investigator
- Principal Investigator
  
  NAKAJIMA Hiroo
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Kyoto Prefectural University of Medicine
Development and Analysis of a Novel Agent of Ascochlorin(ASC) on Estrogen Receptors(ER)-Negative Breast Cancer
- Principal Investigator
  
  SAWAI Kiyoshi
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Kyoto Prefectural University of Medicine
Apoptosis and inflammatory cell in the pathogenesis of acute lung injury
- Principal Investigator
  
  HASHIMOTO Satoru
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Kyoto Prefectural University of Medicine
アポトーシスを誘導する新規免疫調節物質の分子生物学的免疫抑制機序の解析
- Principal Investigator
  
  岡隆宏
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  Kyoto Prefectural University of Medicine
凍結保存血管の移植後動脈硬化性病変に対する分子生物学的制御法の開発
- Principal Investigator
  
  和田行雄
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Thoracic surgery
- Research Institution
  Kyoto Prefectural University of Medicine
Induction of transplantation tolerance based on bio-molecular technique
- Principal Investigator
  
  SUZUKI Seiichi
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (A).
- Research Field
  
  General surgery
- Research Institution
  National Children's Medical Research Center
Analysis of the molecular mechanism of DXR and the therapeutic methodPrincipal Investigator
- Principal Investigator
  
  NAKAJIMA Hiroo
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  Kyoto Prefectural University of Medicine
APOPTOSIS IN ACUTE LUNG INJURY
- Principal Investigator
  
  HASHIMOTO Satoru
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  KYOTO PREFECTURAL UNIVERSITY OF MEDICINE
アポトーシス誘導分子Fasを標的とした癌の免疫療法
- Principal Investigator
  
  山岸久一
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Digestive surgery
- Research Institution
  Kyoto Prefectural University of Medicine
アポトーシス誘導分子の制御による特異的免疫抑制療法の開発Principal Investigator
- Principal Investigator
  
  中嶋啓雄
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  General surgery
- Research Institution
  Kyoto Prefectural University of Medicine
The development of local immunosuppression in organ transplantation
- Principal Investigator
  
  YOSHIMURA Norio
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Kyoto Prefectural University of Medicine
Research about mechanism of delayd xenograft rejection (DXR).
- Principal Investigator
  
  OKA Takahiro
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  Kyoto Prefectural University of Medicine

All 2005 2004

All Journal Article

[Journal Article] Selective cytotoxicity of ascochlorin in ER-negative human breast cancer cell lines.2005
- Author(s)
  Sakaguchi, K., Nakajima, H., Mizuta, N., et al.
- Journal Title
  
  Biochem Biophys Res Commun 329
  
  Pages: 46-50
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591352
[Journal Article] Selective cytotoxicity of ascochlorin in ER-negative human breast cancer cell lines.2005
- Author(s)
  Sakaguchi, K, Nakajima, H., Mizuta, N., et al.
- Journal Title
  
  Biochem Biophys Res Commun 329
  
  Pages: 46-50
- Data Source
  KAKENHI-PROJECT-15591352
[Journal Article] Characterization of 4-O-methyl-ascochlorin-induced apoptosis in comparison with typical apoptotic inducers in human leukemia cell lines2004
- Author(s)
  Tsuruga, M., Nakajima, H., et al.
- Journal Title
  
  Apoptosis 9
  
  Pages: 429-435
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591351

1. OKA Takahiro (60079837)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
2. YOSHIMURA Norio (00191643)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. SUZUKI Seiichi (00111386)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. HASHIMOTO Satoru (90167578)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. SAWAI Kiyoshi (80192102)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. RII Kou (60321890)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. KIMURA Hiromitsu (80115477)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. ENOSAWA Shin (40232962)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. SHINOMIYA Takahisa (30196414)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. SHIME Nobuaki (00260795)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. ONODERA Hideki (50204269)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. MATAUDA Tomoyuki (30281265)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 山岸久一 (40128723)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 和田行雄 (90167213)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 岡本雅彦 (90295650)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 濱島高志 (00238065)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 今西二郎 (40112510)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 小林敦子 (70264778)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 田村明彦

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

NAKAJIMA Hiroo 中嶋 啓雄

中嶋 哲雄 ナカジマ ヒロオ

Research Projects

Research Products

Co-Researchers

トリプルネガティブ乳癌を標的とした新規薬物療法の開発Principal Investigator

Principal Investigator

Project Period (FY)

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A Novel Target Molecule Therapy for Breast Cancer using Tetrocarcin A(TC-A)Principal Investigator

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Principal Investigator

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Analysis of the molecular mechanism of DXR and the therapeutic methodPrincipal Investigator

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Principal Investigator

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アポトーシス誘導分子の制御による特異的免疫抑制療法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

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Research Institution

[Journal Article] Selective cytotoxicity of ascochlorin in ER-negative human breast cancer cell lines.2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] Selective cytotoxicity of ascochlorin in ER-negative human breast cancer cell lines.2005

NAKAJIMA Hiroo 中嶋啓雄

中嶋哲雄ナカジマヒロオ