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Ling Feng  凌 楓

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LING Feng  凌 楓

凌 楓  リョウ フウ

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Researcher Number 70281665
Other IDs
Affiliation (Current) 2025: 国立研究開発法人理化学研究所, 環境資源科学研究センター, 特別嘱託研究員
Affiliation (based on the past Project Information) *help 2018 – 2022: 国立研究開発法人理化学研究所, 環境資源科学研究センター, 専任研究員
2016 – 2017: 国立研究開発法人理化学研究所, 吉田化学遺伝学研究室, 専任研究員
2015: 国立研究開発法人理化学研究所, 吉田化学遺伝学研究室, 研究員
2008 – 2014: The Institute of Physical and Chemical Research, 吉田化学遺伝学研究室, 専任研究員
2013: 独立行政法人理化学研究所, 吉田化学遺伝学研究室, 研究員
2006 – 2007: The Institute of Physical and Chemical Research, 吉田化学遺伝学研究室, 先任研究員
1996 – 1998: 理化学研究所, 遺伝生化学研究室, 研究員
Review Section/Research Field
Principal Investigator
Molecular biology / Basic Section 43010:Molecular biology-related / Genome biology
Except Principal Investigator
Biological Sciences
Keywords
Principal Investigator
ミトコンドリア / ミトコンドリアDNA / 出芽酵母 / ホモプラスミー / コンカテマー / Saccharomyces cerevisiae / ヘテロプラスミー / ローリングサークル型DNA複製 / 組換え / ミトコンドリアDNAの組換え … More / 活性酸素種 / Concatemer / DNA二本鎖切断 / DNA複製 / 酸化ストレス応答 / ローリングサークル型複製 / 除去修復 / 相同DNA対合 / ストレス / 核酸 / 遺伝子 / 遺伝学 / CCE1遺伝子 / DNA組換え / MHR1遺伝子 / 欠失変異mtDNA / mtDNAの組換え / ミトコンドリアのABCトランスポーター / フリードライヒ運動失調症 / 二本鎖切断 / 酸化ストレス / TCA回路 / 超抑制複製 / アポトーシスの活性化因子 / mhr1-1変異 / mtDNAの組換酵素Mhr1 / 経時寿命 / ヌクレオシド / ホモプラスミー化 / mtDNAコピー数 / mtDNA複製 / ローリングサイクル型 / 二本鎖DNA切断 / 相同組換え酵素 / ミトコンドリアDNA複製・修復・分配 / 活性酸素種(ROS) / 過酸化水素 / ローリングサーク型複製 / mtDNAの欠失変異 / 酸素消費速度 / iPS細胞 / マイトファージの活性化 / ローリングサークル型mtDNA複製 / DNA鎖交換体の形成 / 欠失変異ミトコンドリアDNA / 相同的組換え / 相同的DNA対合 / DNA repair / Heteroplasmv / Homoplasmv / Rolling circle DNA replication / Homologous DNA recombination / DNA double-strand break / DNA修復 / 相同DNA組換え / 5’ー3’エキソヌクレアーゼ / ROSスカンベンジャー / チェック・ポイント活性化 / 細胞周期 / ロ-リングサークル型複製 / DNA損傷修復 / DNA二重鎖切断 / 活性酸素種( / チェックポイント / 品質管理 / Rolling-circle type / zygote / replication / mitochondrial fusion / ミトコンドリアヌクレアーゼ / 呼吸鎖複合体 / Mhr1タンク質 / DNA損傷 / ミトコンドリア融合 / Saccharomvces cerevisias / DNAの組換え / 酵素 / 組換え中間体解離酵素 / 組換え中間体 / DNA結合能 / mhr1-1変異体 / 酵素呼吸阻害剤 / 活性酵素種 / ミトコンドリアDNAの安定維持 / mhr1変異 / 遺伝子変換型組換え … More
Except Principal Investigator
NMR / DNAトポロジー / SPOl1 / RecA / 相同対合 / Rad51 / RAD52 / 遺伝的組換え / 天然変性タンパク質 / 分子認識 / バイオテクノロジー / Dな / 酵素 / 蛋白質 / RecA型組換え酵素 / 組換え酵素 / 組換えメディエーター / RecA蛋白質 / RecA/Rad51族組換え酵素 / 相同DNA対合 / Rad51 組換え酵素 / Srs2 DNAヘリカーゼ / RecA族組換え酵素 / Rad52 組換えメディエーター / LOH / 体細胞組換え / 相同DNA組換え / 天然変性領域 Less
  • Research Projects

    (10 results)
  • Research Products

    (85 results)
  • Co-Researchers

    (6 People)
  •  Study on mechanisms for maintenance of mitochondrial DNA integrityPrincipal Investigator

    • Principal Investigator
      凌 楓
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 43010:Molecular biology-related
    • Research Institution
      Institute of Physical and Chemical Research
  •  The studies on the molecular basis of human mitochondrial DNA homoplasmy formationPrincipal Investigator

    • Principal Investigator
      LING Feng
    • Project Period (FY)
      2017 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Molecular biology
    • Research Institution
      Institute of Physical and Chemical Research
  •  Regulatory mechanism for initiating yeast mitochondrial DNA recombination-driven reolication upon nuclear DNA damagePrincipal Investigator

    • Principal Investigator
      LING Feng
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Molecular biology
    • Research Institution
      Institute of Physical and Chemical Research
  •  A Mechanism for Mitochondrial DNA Copy Number-regulated Simultaneous Expression of Proteins in Respiratory Complexes.Principal Investigator

    • Principal Investigator
      LING Feng
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Genome biology
    • Research Institution
      The Institute of Physical and Chemical Research
  •  Functions of intrinsically disordered regions in homologous recombination

    • Principal Investigator
      SHIBATA Takehiko
    • Project Period (FY)
      2009 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      The Institute of Physical and Chemical Research
  •  Analysis of Molecular Mechanism for Regulating Initiation of Recombination-mediated Mitochondrial DNA ReplicationPrincipal Investigator

    • Principal Investigator
      LING Feng
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Molecular biology
    • Research Institution
      The Institute of Physical and Chemical Research
  •  A Novel Regulatory Mechanism for Initiation of Mitochondrial DNA ReplicationPrincipal Investigator

    • Principal Investigator
      FENG Ling
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Molecular biology
    • Research Institution
      The Institute of Physical and Chemical Research
  •  酵母ミトコンドリアDNAの相同的組換えの機能と制御に関する研究Principal Investigator

    • Principal Investigator
      凌 楓
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      The Institute of Physical and Chemical Research
  •  酵母ミトコンドリアDNAの相同的組換えの機能と制御に関する研究Principal Investigator

    • Principal Investigator
      凌 楓
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The Institute of Physical and Chemical Research
  •  酵母ミトコンドリアDNAの相同的組換えの機能と制御に関する研究Principal Investigator

    • Principal Investigator
      凌 楓
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The Institute of Physical and Chemical Research

All 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 Other

All Journal Article Presentation Book Patent

  • [Book] ミトコンドリアダイナミクス(機能から疾患・老化まで)2021

    • Author(s)
      凌 楓、吉田稔 石原直忠ほか82名:
    • Total Pages
      458
    • Publisher
      エヌ・ティー・エス
    • ISBN
      9784860437466
    • Data Source
      KAKENHI-PROJECT-20K06498
  • [Journal Article] Rolling-Circle Replication in Mitochondrial DNA Inheritance: Scientific Evidence and Significance from Yeast to Human Cells2020

    • Author(s)
      Feng Ling, Minoru Yoshida
    • Journal Title

      Genes (Basel)

      Volume: 11(5) Issue: 5 Pages: 514-526

    • DOI

      10.3390/genes11050514

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K07294, KAKENHI-PROJECT-19H05640, KAKENHI-PROJECT-20K06498
  • [Journal Article] Prevention of mitochondrial genomic instability in yeast by the mitochondrial recombinase Mhr12019

    • Author(s)
      Feng Ling, Eliot Bradshaw, Minoru Yoshida
    • Journal Title

      Scientific Reports

      Volume: 9 (1) Issue: 1 Pages: 5433-5445

    • DOI

      10.1038/s41598-019-41699-9

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K07294, KAKENHI-PLANNED-18H05503, KAKENHI-PROJECT-26221204
  • [Journal Article] Regulation of Small Mitochondrial DNA Replicative Advantage by Ribonucleotide Reductase in Saccharomyces cerevisiae2017

    • Author(s)
      Elliot Bradshaw, Minoru Yoshida, *Feng Ling,
    • Journal Title

      G3 (Bethesda)

      Volume: 7 Issue: 9 Pages: 3083-3090

    • DOI

      10.1534/g3.117.043851

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K07294, KAKENHI-PROJECT-26221204
  • [Journal Article] ROS stimulate mitochondrial allele segregation towards homoplasmy in human cells2016

    • Author(s)
      Feng Ling, Rong Niu, Hideyuki Hatakeyama, Yu-ichi Goto, Takehiko Shibata and Minoru Yoshida
    • Journal Title

      Molecular Biology of the Cell

      Volume: 27 Issue: 10 Pages: 1-10

    • DOI

      10.1091/mbc.e15-10-0690

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26440013, KAKENHI-PROJECT-26221204
  • [Journal Article] Din7 and Mhr1 expression levels regulate double-strand-break-induced replication and recombination of mtDNA at ori5 in yeast2013

    • Author(s)
      Feng Ling, Akiko Hori, Ayako Yoshitani, Rong Niu, Minoru Yoshida, and Takehiko Shibata
    • Journal Title

      Nucleic Acids Research

      Pages: 5799-5816

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23510237
  • [Journal Article] Din7 and Mhr1 expression levels regulate double-strand-break–induced replication and recombination of mtDNA at ori5 in yeast2013

    • Author(s)
      Feng Ling, Akiko Hori, Ayako Yoshitani, Rong Niu, Minoru Yoshida and Takehiko Shibata,
    • Journal Title

      Nucleic Acids Research

      Volume: 41 (11) Pages: 5799-5816

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23510237
  • [Journal Article] Din7 and Mhr1 expression levels regulate double-strand-break-induced replication and recombination of mtDNA at ori5 in yeast2013

    • Author(s)
      *Feng Ling, Akiko Hori, Ayako Yoshitani, Rong Niu, Minoru Yoshida and Takehiko Shibata
    • Journal Title

      Nucleic Acids Research

      Volume: 41(8) Issue: 11 Pages: 5799-5816

    • DOI

      10.1093/nar/gkt273

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23510237
  • [Journal Article] Mitochondrial fission proteins Fis1 and Mdv1, but not Dnm1, play a role in maintenance of heteroplasmy in budding yeast2012

    • Author(s)
      Elliot Bradshaw, Minoru Yoshida and Feng Ling
    • Journal Title

      FEBS Letters

      Volume: 586(8) Pages: 1245-1251

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23510237
  • [Journal Article] Increases in Mitochondrial DNA Content and 4977-bp Deletion Upon ATM/Chk2 Checkpoint Activation in HeLa Cells2012

    • Author(s)
      Rong Niu, Minoru Yoshida and *Feng Ling
    • Journal Title

      PLoS ONE

      Volume: 7(7)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23510237
  • [Journal Article] Increased 4977-bp deletion in mitochondrial DNA upon ATM/Chk2 checkpoint activation in HeLa cells2012

    • Author(s)
      Rong Niu, Minoru Yoshida and Feng Ling
    • Journal Title

      PLoS One

      Volume: 7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23510237
  • [Journal Article] Enlightenment of yeast mitochondrial homoplasmy : diversified roles of gene conversion2011

    • Author(s)
      Feng Ling
    • Journal Title

      Genes

      Volume: 2 Pages: 169-190

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20570171
  • [Journal Article] Gene conversion through double-strand break-induced DNA replication and mitochondrial homoplasmy2011

    • Author(s)
      Feng Ling, Tsutomu Mikawa and Takehiko Shibata
    • Journal Title

      Genes

      Volume: 2 Pages: 169-190

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23510237
  • [Journal Article] Mitochondrial fusion increases the mitochondrial DNA copy number in budding yeast2011

    • Author(s)
      Akiko Hori, Minoru Yoshida and Feng Ling
    • Journal Title

      Genes to Cells

      Volume: 16 Pages: 527-544

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23510237
  • [Journal Article] Enlightenment of yeast mitochondrial homoplasmy : diversified roles of gene conversion2011

    • Author(s)
      Ling, F.
    • Journal Title

      Genes

      Volume: 2 Pages: 169-190

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-21113004
  • [Journal Article] Enlightenment of yeast mitochondrial homoplasmy : diversified roles of gene conversion2011

    • Author(s)
      Ling, F., Mikawa, T. and Shibata, T.
    • Journal Title

      Genes (Basel)

      Volume: 2 Issue: 1 Pages: 169-190

    • DOI

      10.3390/genes2010169

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-21113004, KAKENHI-PROJECT-22570147, KAKENHI-PROJECT-23510237
  • [Journal Article] Gene conversion through double-strand break-induced DNA replication and mitochondrial homoplasmy2011

    • Author(s)
      Feng Ling, Tsutomu Mikawa, Takehiko Shibata
    • Journal Title

      Genes 2

      Pages: 169-190

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20570171
  • [Journal Article] Analysis of DNA-binding sites on Mhr1, a yeast mitochondrial ATP-independent homologous pairing protein2010

    • Author(s)
      Tokiha Masuda, Feng Ling, Takehiko Shibata, Tsutomu Mikawa
    • Journal Title

      FEBS Journal 277

      Pages: 1440-1452

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20570171
  • [Journal Article] Analysis of DNA-binding sites on Mhr1, a yeast mitochondrial ATP-independent homologous pairing protein2010

    • Author(s)
      Masuda, T., Ling, F., Shibata, T. and Mikawa, T.
    • Journal Title

      FEBS J.

      Volume: 277 Pages: 1440-1452

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-21113004
  • [Journal Article] Heteroduplex joint formation free of net topological change by Mhr1, a mitochondrial recombinase2009

    • Author(s)
      Feng Ling
    • Journal Title

      The Journal of Biological Chemistry 284

      Pages: 9341-9353

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20570171
  • [Journal Article] Negative supercoil interference with homologous pairing mediated by Mhr1, an ATP-independent recombinase structurally unrelated to RecA/Rad512009

    • Author(s)
      Feng Ling, Minoru Yoshida, Takehiko Shibata
    • Journal Title

      The Journal of Biological Chemistry 284

      Pages: 9341-9353

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20570171
  • [Journal Article] Heteroduplex joint formation free of net topological change by Mhr1, a mitochondrial recombinase2009

    • Author(s)
      Ling, F.
    • Journal Title

      J.Biol.Chem. 284

      Pages: 9341-9353

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-21113004
  • [Journal Article] Heteroduplex joint formation free of net topological change by Mhr1, a mitochondrial recombinase2009

    • Author(s)
      Feng Ling
    • Journal Title

      Journal of Biological Chemistry 284(印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20570171
  • [Journal Article] Reactive oxygen species contribute to recombination-mediated replication to regulate the mitochondrial DNA copy number2009

    • Author(s)
      Akiko Hori, Minoru Yoshida, Takehiko Shibata, Feng Ling
    • Journal Title

      Nucleic Acids Research 37

      Pages: 749-761

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20570171
  • [Journal Article] Heteroduplex joint formation free of net topological change by Mhr1, a mitochondrial recombinase2009

    • Author(s)
      Ling, F., Yoshida, M. and Shibata, T.
    • Journal Title

      J. Biol. Chem.

      Volume: 284 Pages: 9341-9353

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-21113004
  • [Journal Article] A novel cis-acting element required for DNA damage-inducible expression of yeast DIN72008

    • Author(s)
      Ayako Yoshitani, Minoru Yoshida, and Feng Ling,
    • Journal Title

      Bioehemical and Biophysical Research Communication 365

      Pages: 183-188

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18570168
  • [Journal Article] A novel cis-acting element required for DNA damage-inducible expression of yeast DIN7.2008

    • Author(s)
      Ayako Yoshitani, Minoru Yoshida, Feng Ling
    • Journal Title

      Biochemical and Biophysical Research Communications 365(1)

      Pages: 183-188

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20570171
  • [Journal Article] The yeast checkpoint kinase Dun1 down-regulates DIN7 in the absence of DNA damage2008

    • Author(s)
      Ayako Yoshitani, Feng Ling, Minoru Yoshida
    • Journal Title

      Bioscience, Biotechnology, and Biochemistry 72(6)

      Pages: 1630-1634

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20570171
  • [Journal Article] A novel cis-acting element required for DNA damage-inducilble experession of yeast DIN72008

    • Author(s)
      Ayako Yoshitani, Minoru Yoshida, Feng Ling
    • Journal Title

      Biochemical and Biophysical Research Communication 365

      Pages: 183-188

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18570168
  • [Journal Article] DNA recombination-Initiation plays a role in the extremely biased inheritance of yeast[rho] mitochondrial DNA that contains the replication origin ori52007

    • Author(s)
      Feng Ling, Akiko Hore, Takehiko Shibata
    • Journal Title

      Molecular and Cellular Biology 27

      Pages: 1133-1145

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18570168
  • [Journal Article] DNA Recombination-Initiation Plays a Role in the Extremely Biased Inheritance of Yeast[rho-]Mitochondrial DNA That Contains the Replication Origin ori52007

    • Author(s)
      Feng Ling, Akiko Hori, and Takehiko Shibata
    • Journal Title

      MOLECULAR AND CELLULAR BIOLOGY 27

      Pages: 1133-1145

    • Data Source
      KAKENHI-PROJECT-18570168
  • [Journal Article] DNA recombination-Initiation plays a role in the extremely biased inheritance of yeast [rho] mitochondrial DNA that contains the replication origin ori52007

    • Author(s)
      Feng Ling, Akiko Hori, and Takehiko Shibata
    • Journal Title

      Moleeular and cellular biology 27

      Pages: 1133-1145

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18570168
  • [Journal Article] DNA recombination protein-dependent mechanism of homoplasmy and its proposed functions2007

    • Author(s)
      Takehiko Shibata, Feng Ling
    • Journal Title

      Mitochondrion 7

      Pages: 17-23

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18570168
  • [Journal Article] DNA recombination protein-dependent mechanism of homoplasmy and its proposed functions2007

    • Author(s)
      Takehiko Shibata and Feng Ling,
    • Journal Title

      Mitochondrion 7

      Pages: 17-23

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18570168
  • [Journal Article] ローリングサークル型DNA複製:ミトコンドリアDNAコピー数制御機構の新しい普遍的モデル2007

    • Author(s)
      凌 楓
    • Journal Title

      蛋白質核酸酵素 52

      Pages: 886-892

    • NAID

      40015530565

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18570168
  • [Journal Article] a universal model for controlling mechanisms of mitochondrial DNA copy number2007

    • Author(s)
      Feng Ling, Akiko Hori, Minoru Yoshida, Takehiko Shibata Rolling circle replication
    • Journal Title

      Tanpakushitsu Kakusan Koso 52(8)

      Pages: 886-92

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18570168
  • [Journal Article] DNA recombination-Initiation plays a role in the extremely biased inheritance of yeast [rho^-] mitochondrial DNA that contains the replication origin ori52007

    • Author(s)
      Feng Ling
    • Journal Title

      Molecular and Cellular Biology 27

      Pages: 1133-1145

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18570168
  • [Journal Article] ローリングサークル型DNA複製:ミトコンドリアDNAコピー数制御機構の新しい普遍的モデル2007

    • Author(s)
      凌 楓、堀 晶子、吉田 稔、柴田 武彦
    • Journal Title

      蛋白質核酸酵素 52

      Pages: 886-892

    • NAID

      40015530565

    • Data Source
      KAKENHI-PROJECT-18570168
  • [Patent] ヘテロプラスミー細胞をホモプラスミー化する方法2009

    • Inventor(s)
      凌楓、柴田武彦、牛栄、吉田稔、後藤雄一
    • Industrial Property Rights Holder
      独立行政法人理化学研究所
    • Industrial Property Number
      2009-285729
    • Filing Date
      2009-12-16
    • Data Source
      KAKENHI-PROJECT-20570171
  • [Presentation] Major apurine/apyrimidinic endonuclease Apn1 plays a rol in the highly biased inheritance of yeast[rho-] mitochondrial DNA in budding yeast2021

    • Author(s)
      凌楓、朱文娟、吉田稔
    • Organizer
      FY2021 CSRS interim Progress ReportMeeting
    • Data Source
      KAKENHI-PROJECT-20K06498
  • [Presentation] ミトコンドリアDNA遺伝の新機構と応用の可能性2021

    • Author(s)
      凌楓
    • Organizer
      令和3年度第二回名古屋産学官・医連携研究会(名古屋連携研究会: NJK)
    • Invited
    • Data Source
      KAKENHI-PROJECT-20K06498
  • [Presentation] eIF5A ハイプシン化阻害剤 GC7 によるミトコンドリア制御2020

    • Author(s)
      松本 健、黒川留美、凌 楓、鈴木健裕、堂前 直、吉田 稔
    • Organizer
      日本ポリアミン学会年会
    • Data Source
      KAKENHI-PROJECT-17K07294
  • [Presentation] A new paradigm of eukaryotic mitochondrial genetic inheritance revealed from studies on yeast mitochondrial DNA replication2020

    • Author(s)
      ◯ Ling Feng, Yoshida Minoru
    • Organizer
      第43回日本分子生物学会年会
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K07294
  • [Presentation] A new paradigm of eukaryotic mitochondrial genetic inheritance revealed from studies on yeast mitochondrial DNA replication2020

    • Author(s)
      ◯Ling Feng, Yoshida Minoru
    • Organizer
      第43回日本分子生物学会年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20K06498
  • [Presentation] The mitochondrial recombinase Mhr1 sustains yeast chronological life span2019

    • Author(s)
      Feng Ling、Minoru Yoshida
    • Organizer
      国立研究開発法人理化学研究所環境資源科学研究センターの中間発表
    • Data Source
      KAKENHI-PROJECT-17K07294
  • [Presentation] Effects of GC7, a potent inhibitor of eIF5A hypusination, on mitochondrial proteins2019

    • Author(s)
      松本 健、黒川留美、Mohammad Tariq、Tilman Schneider-Poetsch、凌 楓、 室井 誠、鈴木健裕、堂前 直、伊藤昭博、長田裕之、吉田 稔
    • Organizer
      第42回日本分子生物学会
    • Data Source
      KAKENHI-PROJECT-17K07294
  • [Presentation] Mitochondral DNA recombination is critical for sustaining yeast chronological lifespan2018

    • Author(s)
      Feng LING
    • Organizer
      Annual Meeting of Aging project 2018
    • Data Source
      KAKENHI-PROJECT-17K07294
  • [Presentation] A mechanism for oxidative stress-stimulated mitochondrial DNA homoplasmy2016

    • Author(s)
      Feng LING, Rong Niu, T. Shibata, Y. Goto, Hatakeyama, H., and M. Yoshida
    • Organizer
      第39回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2016-11-30
    • Data Source
      KAKENHI-PROJECT-26440013
  • [Presentation] A novel mechanism for human mitochondrial allele segregation towards homoplasmy2016

    • Author(s)
      Feng LING
    • Organizer
      Global Conference of Chinese Geneticists
    • Place of Presentation
      Zhejiang University, Hangzhou, Zhejiang Province, China
    • Year and Date
      2016-09-23
    • Data Source
      KAKENHI-PROJECT-26440013
  • [Presentation] DNA組換えに立脚したミトコンドリア遺伝の仕組みに関する研究2015

    • Author(s)
      凌楓
    • Organizer
      柴田武彦先生古稀記念シンポジウム
    • Place of Presentation
      早稲田大学大隈会館
    • Year and Date
      2015-03-07
    • Data Source
      KAKENHI-PROJECT-26440013
  • [Presentation] 健全な iPS 細胞樹立に向けたミトコンドリア病患者細胞の mtDNA ホモプラスミー化促進法の開発2014

    • Author(s)
      凌楓、牛栄、柴田武彦、吉田稔、畠山英之、後藤雄一
    • Organizer
      CREST/さきがけ/JST-CIRM 合同シンポジウム
    • Place of Presentation
      東京都江東区青海2-3-6 日本科学未来館
    • Year and Date
      2014-01-15
    • Data Source
      KAKENHI-PROJECT-23510237
  • [Presentation] Role of Recombination-mediated Replication in Mitochondrial Inheritance2012

    • Author(s)
      Feng Ling
    • Organizer
      The Glycobiology Forum at Jiang Nan University
    • Place of Presentation
      School of Biotechnology, Jiangnan University, No. 188800 Lihu Avenue, Wuxi, Jiangsu, P. C. 214122, China
    • Year and Date
      2012-07-10
    • Data Source
      KAKENHI-PROJECT-23510237
  • [Presentation] A Novel Mechanism for Mitochondrial Inheritance & Its Biomedical Importance2012

    • Author(s)
      Feng Ling
    • Organizer
      Symposium of Mitochondral Biomedicine
    • Place of Presentation
      Zhejiang University in Hangzhou, Zhejiang Province, China
    • Data Source
      KAKENHI-PROJECT-23510237
  • [Presentation] Recombination-mediated Replication in Mitochondrial DNA Inheritance2012

    • Author(s)
      Feng Ling, Rong Niu, Eliot Bradshaw, Minoru Yoshida
    • Organizer
      Global Conference of Chinese Geneticists
    • Place of Presentation
      Zhejiang University in Hangzhou, Zhejiang Province, China
    • Data Source
      KAKENHI-PROJECT-23510237
  • [Presentation] A Novel Mechanism for Mitochondrial DNA Inheritance and its Medical Significance2012

    • Author(s)
      Feng Ling
    • Organizer
      Mitochondrial Genetics Forum at Peking University
    • Place of Presentation
      Peking University First Hospital, Xi-shi-ku St, Beijing 100034, China
    • Year and Date
      2012-08-29
    • Data Source
      KAKENHI-PROJECT-23510237
  • [Presentation] Recombination-mediated Replication in Mitochondrial DNA Inheritance2012

    • Author(s)
      ○Feng Ling, Rong Niu, Eliot Bradshaw, Minoru Yoshida
    • Organizer
      Global Conference of Chinese Geneticists,
    • Place of Presentation
      Zhejiang University in Hangzhou, Zhejiang Province, China
    • Invited
    • Data Source
      KAKENHI-PROJECT-23510237
  • [Presentation] Mitochondrial DNA homoplasmy as gene homogenization of repeated sequences by rolling circle replication.2011

    • Author(s)
      Feng Ling, Rong Niu, Elliot Bradshaw, Takehiko Shibata, Minoru Yoshida
    • Organizer
      RIKEN Joint Retreat 2011
    • Place of Presentation
      Yamaha Resort Tsumagi, Kakegawa, Shizuoka
    • Year and Date
      2011-01-31
    • Data Source
      KAKENHI-PROJECT-20570171
  • [Presentation] Mitochondrial DNA homoplasmy as gene homogenization of repeated sequences by rolling circle replication.2011

    • Author(s)
      Takehiko Shibata, Feng Ling, Tsutomu Mikawa
    • Organizer
      The 7th conference of Asian Societyfor mitochondrial research and Medicine and 10th Japanese Society for mitochondrial research and Medicine
    • Place of Presentation
      Fukuoka city
    • Year and Date
      2011-12-16
    • Data Source
      KAKENHI-PROJECT-20570171
  • [Presentation] A Molecular Mechanism for Mitochondrial DNA Homoplasmy and its Application2011

    • Author(s)
      Feng Ling
    • Organizer
      RIKEN Joint Retreat 2011
    • Place of Presentation
      Yamaha Resort Tsumagi, Kakegawa, Shizuoka
    • Year and Date
      2011-01-31
    • Data Source
      KAKENHI-PROJECT-20570171
  • [Presentation] 相同組換え開始制御に働く天然変性タンパク質の機能2010

    • Author(s)
      柴田 武彦, 新井 直人, 香川 亘, 胡桃坂仁志, 増田 ときは, 美川 務, 新宮 良宣, 堀 晶子, 凌 楓
    • Organizer
      第10回日本蛋白質科学会年会
    • Place of Presentation
      札幌 日本
    • Data Source
      KAKENHI-PLANNED-21113004
  • [Presentation] Mitochondrial DNA homoplasmy as gene homogenization of repeated sequences by rolling circle replication2010

    • Author(s)
      Shibata, T., Ling, F. and Mikawa, T.
    • Organizer
      7th Conference of Asian Society for Mitochondrial Research and Medicine(ASMRM) and 10th Conference of Japanese Society of Mitochondrial Research and Medicine (J-mit)
    • Place of Presentation
      Fukuoka, Japan
    • Data Source
      KAKENHI-PLANNED-21113004
  • [Presentation] ROSで誘導される組換え依存型ミトコンドリアDNA複製2009

    • Author(s)
      凌楓、堀晶子,牛栄、柴田武彦、吉田稔
    • Organizer
      第9回日本ミトコンドリア学会年会
    • Place of Presentation
      東京大学医学部鉄門記念講堂
    • Year and Date
      2009-12-17
    • Data Source
      KAKENHI-PROJECT-20570171
  • [Presentation] ミトコンドリアDNAコピー数を増加させるミトコンドリア融合2009

    • Author(s)
      堀晶子、吉田稔、凌楓
    • Organizer
      第32回日本分子生物学年会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2009-12-10
    • Data Source
      KAKENHI-PROJECT-20570171
  • [Presentation] DNAの位相幾何学的変化を伴わない組換え中間体形成2008

    • Author(s)
      柴田武彦、凌楓
    • Organizer
      第26回染色体ワークショップ
    • Place of Presentation
      姫路
    • Year and Date
      2008-01-16
    • Data Source
      KAKENHI-PROJECT-20570171
  • [Presentation] 酵母ミトコンドリアDNA複製開始点での二重鎖切断修復に働く相同DNA対合酵素Mhr12008

    • Author(s)
      凌楓、堀晶子、柴田武彦、吉田稔
    • Organizer
      第31回日本分子生物学会年会・第81回日本生化学会大会 合同大会(BMB2008)
    • Place of Presentation
      神戸
    • Year and Date
      2008-12-10
    • Data Source
      KAKENHI-PROJECT-20570171
  • [Presentation] ミトコンドリアの相同組換え酵素反応へのDNAの高次構造の効果2008

    • Author(s)
      凌楓
    • Organizer
      第8回日本ミトコンドリア学会年会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-20570171
  • [Presentation] ミトコンドリアの相同組換え酵素反応へのDNAの高次構造の効果2008

    • Author(s)
      凌楓、吉田稔、柴田武彦
    • Organizer
      第8回日本ミトコンドリア学会年会
    • Place of Presentation
      神戸
    • Year and Date
      2008-12-14
    • Data Source
      KAKENHI-PROJECT-20570171
  • [Presentation] ミトコンドリアゲノムの遺伝的均一化におけるDNA損傷応答因子Din7の役割2007

    • Author(s)
      凌 楓、柴田武彦、堀 晶子、吉田稔
    • Organizer
      バイオアーキテクトシンポジウム
    • Place of Presentation
      独立行政法人理化学研究所和光研究所鈴木梅太郎記念ホール
    • Year and Date
      2007-09-11
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18570168
  • [Presentation] A role of DNA damage-inducible protein, Din7 in recombination-mediated mitochondrial DNA replication2007

    • Author(s)
      Feng Ling, Akiko Hori, Minoru Yoshida and Takehiko Shibata
    • Organizer
      FASEB Summer Research Conference on Genetic Recombination & Genome Rearrangements
    • Place of Presentation
      Snowmass Village, Colorado, USA
    • Year and Date
      2007-07-29
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18570168
  • [Presentation] A role of DNA damage-inducible protein,Din7 in recombination-mediated mitochondrial DNA replication2007

    • Author(s)
      Feng Ling, Akiko Hori, Minoru Yoshida and Takehiko Shibata
    • Organizer
      FASEB Summer Research Conference on Genetic Recombination & Genome Rearrangements
    • Place of Presentation
      Snowmass Village,Colorado,USA
    • Year and Date
      2007-07-29
    • Data Source
      KAKENHI-PROJECT-18570168
  • [Presentation] An accelerated increases of mtDNA copy number by reactive oxygen species and its possible mechanism2007

    • Author(s)
      Akiko Hori, Feng Ling, Takehiko Shibata, Minoru Yoshida
    • Organizer
      Biochemistry and Molecular Biology, Yokohama(Pacifico Yakohama, InterContinental Yokohama Grand)
    • Place of Presentation
      Japan
    • Year and Date
      2007-12-13
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18570168
  • [Presentation] The promoting mechanism of mtDNA copy number in hydrogen peroxide-treated isolated mitochondria2007

    • Author(s)
      Akiko Hori, Feng Ling, Takehiko Shibata, Minoru Yoshida
    • Organizer
      The 7th Annual Conference of the Japanese Society of Mitochondrial Research and Medicine(J-mit)
    • Place of Presentation
      Kagoshima, Japan
    • Year and Date
      2007-12-20
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18570168
  • [Presentation] ミトコンドリアゲノムの遺伝的均一化におけるDNA損傷応答因子Din7の役割2007

    • Author(s)
      堀 晶子、凌 楓、柴田 武彦、吉田 稔
    • Organizer
      ミトコンドリア学会第7回年会
    • Place of Presentation
      南日本新聞社南ホール鹿児島
    • Year and Date
      2007-12-20
    • Data Source
      KAKENHI-PROJECT-18570168
  • [Presentation] A role of DNA damage-responding protein, Din7 in the establishment of mitochondrial homoplasmy2007

    • Author(s)
      Feng Ling, Takehiko Shibata, Akiko Hori, Minoru Yoshida
    • Organizer
      Bioarchitect symposium RIKEN(Umetaro Memorial Hall)
    • Place of Presentation
      Japan
    • Year and Date
      2007-09-11
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18570168
  • [Presentation] A role of DNA damage-inducible protein, Din7 in recombination・mediated mitochondrial DNA replication2007

    • Author(s)
      Feng Ling, Akiko Hori, Minoru Yoshida, Takehiko Shibata
    • Organizer
      FASEB Summer Research Conference on Genetic Recombination&Genome Rearrangements
    • Place of Presentation
      Snowmas Village, Colorado, USA
    • Year and Date
      2007-07-29
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18570168
  • [Presentation] 活性酸素種に夜mtDNAコピー数増加とその可能なメカニズム2007

    • Author(s)
      堀 晶子、凌 楓、柴田 武彦、吉田 稔
    • Organizer
      第30回日本分子生物学会年会第80回日本生化学会年会合同大会
    • Place of Presentation
      パシフィコ横浜ヨコハマグランドインターコンチネンタルホテル
    • Year and Date
      2007-12-04
    • Data Source
      KAKENHI-PROJECT-18570168
  • [Presentation] ミトコンドリアのエキソヌクレアーゼによる不安定化からゲノムを守る出芽酵母の相同DNA対合酵素Mhr12007

    • Author(s)
      凌 楓、柴田武彦、堀 晶子、吉田 稔
    • Organizer
      第30回日本分子生物学会年会第80回日本生化学会年会合同大会
    • Place of Presentation
      パシフィコ横浜ヨコハマグランドインターコンチネンタルホテル
    • Year and Date
      2007-12-14
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18570168
  • [Presentation] 活性酸素種によるmtDNAコピー数増加とその可能なメカニズム2007

    • Author(s)
      堀 晶子、凌 楓、柴田武彦、吉田 稔
    • Organizer
      第30回日本分子生物学会年会第80回日本生化学会年会合同大会
    • Place of Presentation
      パシフィコ横浜ヨコハマグランドインターコンチネンタルホテル
    • Year and Date
      2007-12-13
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18570168
  • [Presentation] 単離ミトコンドリア解析で明されたROSによるmtDNAコピー数制御機構2007

    • Author(s)
      堀 晶子、凌 楓、柴田武彦、吉田 稔
    • Organizer
      ミトコンドリア学会第7回年会
    • Place of Presentation
      南日本新聞社南ホール鹿児島
    • Year and Date
      2007-12-20
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18570168
  • [Presentation] A homologous DNA pairing-promoting Mhrlp functions to prevent mtDNA instability caused by overproducing Din7p, an exo-Dnase in yeast2007

    • Author(s)
      Feng Ling, Takehiko Shibata, Akiko Hori, Minoru Yoshida
    • Organizer
      Biochemistry and Molecular Biology, Yokohama(Pacifico Yakohama, InterContinental Yokohama Grand)
    • Place of Presentation
      Japan
    • Year and Date
      2007-12-14
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18570168
  • [Presentation] 健全なiPS細胞樹立に向けたミトコンドリア病患者細胞のmtDNAホモプラスミー化促進法の開発

    • Author(s)
      凌楓、牛栄、柴田武彦、吉田稔、畠山英之、後藤雄一
    • Organizer
      CREST/さきがけ/JST-CIRM 合同シンポジウム
    • Place of Presentation
      東京都江東区青海2-3-6 日本科学未来館
    • Data Source
      KAKENHI-PROJECT-23510237
  • [Presentation] 出芽酵母のミトコンドリアDNAの複製開始領域に起きる二重鎖切断導入機構

    • Author(s)
      堀晶子、柴田武彦、吉田稔、凌楓
    • Organizer
      第31回日本分子生物学会年会・第81回日本生化学会大会 合同大会(BMB2008)
    • Data Source
      KAKENHI-PROJECT-20570171
  • [Presentation] Role of Recombination-mediated Replication in Mitochondrial Inheritance

    • Author(s)
      Feng Ling
    • Organizer
      The Glycobiology Forum at Jiang Nan University, School of Biotechnology, Jiangnan University,
    • Place of Presentation
      No. 188800 Lihu Avenue, Wuxi, Jiangsu, P.C. 214122, China
    • Invited
    • Data Source
      KAKENHI-PROJECT-23510237
  • [Presentation] A Novel Mechanism for Mitochondrial DNA Inheritance and its Medical Significanc

    • Author(s)
      Feng Ling
    • Organizer
      Mitochondrial Genetics Forum at Peking University
    • Place of Presentation
      Peking University First Hospital, Xi-shi-ku St, Beijing 100034, China
    • Invited
    • Data Source
      KAKENHI-PROJECT-23510237
  • [Presentation] 健全なiPS細胞樹立に向けたミトコンドリア病患者細胞のmtDNAホモプラスミー化機構の解析

    • Author(s)
      凌楓、牛栄、小林大貴、吉田稔、畠山英之、後藤雄一
    • Organizer
      CREST 「iPS細胞」領域 研究領域ミーティング
    • Place of Presentation
      兵庫県立淡路夢舞台国際会議場
    • Year and Date
      2014-10-28 – 2014-10-29
    • Data Source
      KAKENHI-PROJECT-26440013
  • 1.  INOUE Jin (10469893)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 2.  SHIBATA Takehiko (70087550)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 3.  KUSANO Kohji (70336098)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  ARAI Naoto (70297795)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 5.  KAGAWA Wataru (70415123)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 6.  KIKAWA Tsutomu (20321820)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results

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