Ichikawa Wataru 市川度

… Alternative Names

ICHIKAWA Wataru 市川度

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Researcher Number	70282738
External Links
Affiliation (Current)	2025: 昭和大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2007: Saitama Medical University, Medicine, Associate professor 2005 – 2006: Saitama Medical School, Medicine, Associate professor, 医学部, 助教授 2004: 埼玉医科大学, 医学部, 教授 2001 – 2003: 埼玉医科大学, 医学部, 講師 2000: Tokyo Medical & Dental University, instructor, 大学院・医歯学総合研究科, 助手 1998 – 1999: 東京医科歯科大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Digestive surgery / Digestive surgery Except Principal Investigator Digestive surgery
Keywords	Principal Investigator DNA array / 5-FU / prediction / DPD / TS / LCM / gene expression / fluoronyrimidine / 副作用 / 治療効果 … More / マイクロアレイ / 遺伝子発現 / フッ化ピリミジン / DNAアレイ / northern hybridization / Cancer / real-time PCR / 胃癌 / レーザーマイクロダイセクション / 遺伝子多型 / 大腸癌 / thymidylate synthase / 抗癌剤感受性 / 癌 / gastro-intestinal cancer / nuclear matrix protein / cancer-specific antigen / 癌特異的 / モノクローナル抗体 / 化学療法 / 消化器癌 / アポトーシス / 核マトリックス蛋白 … More Except Principal Investigator E-cadherin / methylation / p14^<ARF> gene / Gastric cancer / 家族性胃癌 / MSI / genomic instability / メチル化 / p14^<ARF>遺伝子 / Eカドヘリン / 胃癌 Less

Development of new system to predict clinical outcome of anti-cancer agent using peripheral lymphocytePrincipal Investigator
- Principal Investigator
  
  ICHIKAWA Wataru
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Saitama Medical University
Development and clinical application of high-sensitive focused DNA arrayPrincipal Investigator
- Principal Investigator
  
  ICHIKAWA Wataru
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Saitama Medical School
Gene analysis in gastric cancer using with laser captured micro-dissectionPrincipal Investigator
- Principal Investigator
  
  ICHIKAWA Wataru, 代田喜典
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Saitama Medical School
  Tokyo Medical and Dental University
Studies on genomic instability of gastric cancer
- Principal Investigator
  
  NIHEI Zenro
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Tokyo Medical and Dental University
Expression of cancer-specific nuclear matrix protein in gastro-intestinal cancerPrincipal Investigator
- Principal Investigator
  
  ICHIKAWA Wataru
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Tokyo Medical and Dental University

All 2008 2007 2006 2005 2004 2003

All Journal Article Presentation

[Journal Article] The Unanswered Question:What is the Determinant of S-1 pharmacokinetics?2008
- Author(s)
  Ichikawa W, et. al.
- Journal Title
  
  Clin Pharmacol Ther. (e-pub)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591481
[Journal Article] Re:UGT1A1^*28 genotype and irinotecan-induced neutropenia:dose matters.2008
- Author(s)
  Ichikawa W, et. al.
- Journal Title
  
  J Natl Cancer Inst 100
  
  Pages: 224-225
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591481
[Journal Article] Re:UGTIAI*28 genotype and irinotecan-induced neutropenia:dose matters2008
- Author(s)
  Ichikawa W, et. al.
- Journal Title
  
  J Natl Callcer Inst 100
  
  Pages: 224-225
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591481
[Journal Article] The Unanswered Question : What Is the Determinant of S-1 Pharmacokinetics2008
- Author(s)
  Ichikawa, W, Fujita, K, Sasaki, Y
- Journal Title
  
  Clin Pharmacol Ther 26(E-pub)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591481
[Journal Article] The Unanswered Question:What is the Determinant of S-1 pharmacokinetics2008
- Author(s)
  Ichikawa W, et. al.
- Journal Title
  
  Clin Pharmacol Ther (印刷中)
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591481
[Journal Article] CYP2A6 and the plasma level of 5-chloro-2, 4-dihydroxypyridine are determinants of the pharmacokinetic variability of tegafur and 5-fluorouracil, respectively, in Japanese patients with cancer given S-12008
- Author(s)
  Fujita, K, Yamamoto, W, Endo, S, Endo, H, Nagashima, F, Ichikawa, W, et. al.
- Journal Title
  
  Cancer Sci 99(5)
  
  Pages: 1049-54
- NAID
  10024006554
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591481
[Journal Article] Re : UGT1A1*28 genotype and irinotecan-induced neutropenia : dose matters2008
- Author(s)
  Ichikawa, W, Araki, K, Fujita, K, et. al.
- Journal Title
  
  J Natl Cancer Inst 100(3)
  
  Pages: 224-5
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591481
[Journal Article] Orotate phosphoribosyltransferase gene polymorphism predicts toxicity in patients treated with bolus 5-fluorouracil regimen.2006
- Author(s)
  Ichikawa W, et al.
- Journal Title
  
  Clin Cancer Res 12・13
  
  Pages: 3928-34
- Data Source
  KAKENHI-PROJECT-18591481
[Journal Article] 消化器癌の外来化学療法消化器癌の外来化学療法で用いられる抗悪性腫瘍薬とその特徴2006
- Author(s)
  市川度, 加藤高晴, 平山廉三
- Journal Title
  
  消化器外科 28・10
  
  Pages: 1557-1568
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591437
[Journal Article] Gene expression of ferredoxin reductase predicts outcome in patients with metastatic colorectal cancer treated by 5-fluorouracil plus leucovorin.2006
- Author(s)
  Ichikawa W, Ooyama A, Toda E, Sugimoto Y, Oka T, Takahashi T, Shimizu M, Sasaki Y, Hirayama R.
- Journal Title
  
  Cancer Chemother Pharmacol. May (Epub ahead of print)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591437
[Journal Article] Simple combinations of 5-FU pathway genes predict the outcome of metastatic gastric cancer patients treated by S-1.2006
- Author(s)
  Ichikawa W, et al.
- Journal Title
  
  Int J Cancer 119・8
  
  Pages: 1927-33
- Data Source
  KAKENHI-PROJECT-18591481
[Journal Article] Prediction of clinical outcome of fluoropyrimidine-based chemotherapy for Gastric cancer patients, in terms of the 5-fluorouracil metabolic pathway.2006
- Author(s)
  Ichikawa, W
- Journal Title
  
  Gastric Cancer 9(3)
  
  Pages: 145-55
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591481
[Journal Article] 抗癌剤感受性予測因子研究の進歩と今後の展開2006
- Author(s)
  代田喜典, 市川度
- Journal Title
  
  G. I. Research 14・1
  
  Pages: 20-28
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591437
[Journal Article] 消化器癌の外来化学療法消化器癌の外来化学療法のための副作用対策2006
- Author(s)
  市川度, 仁瓶善郎, 平山廉三
- Journal Title
  
  消化器外科 28・11
  
  Pages: 1691-1699
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591437
[Journal Article] 【各種癌における予後因子と治療効果予測因子】転移性消化器癌における治療効果予測因子2006
- Author(s)
  市川度, 高橋威洋, 須藤謙一, 平山廉三
- Journal Title
  
  Biotherapy 19・3
  
  Pages: 248-254
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591437
[Journal Article] Gene expression of ferredoxin reductase predicts outcome in patients with metastatic colorectal cancer treated by 5-fluorouracil plus leucovorin.2006
- Author(s)
  Ichikawa W, et al.
- Journal Title
  
  Cancer Chemother Pharmacol 58・6
  
  Pages: 794-801
- Data Source
  KAKENHI-PROJECT-18591481
[Journal Article] 抗癌剤感受性予測因子研究の進歩と今後の展開2006
- Author(s)
  代田喜典, 市川度
- Journal Title
  
  G.I.Research 14・1
  
  Pages: 20-28
- Data Source
  KAKENHI-PROJECT-15591437
[Journal Article] Prediction of clinical outcome of fluoropyrimidine-based chemotherapy for gastric cancer patients, in terms of the 5-fluorouracil metabolic pathway2006
- Author(s)
  Ichikawa W
- Journal Title
  
  Gastric Cancer 9・3
  
  Pages: 145-55
- Data Source
  KAKENHI-PROJECT-18591481
[Journal Article] Gene expression of ferredoxin reductase predicts outcome in patients with metastatic colorectal cancer treated by 5-fluorouracil plus leucovorin.2006
- Author(s)
  W.Ichikawa, A.Ooyama, E.Toda, Y.Sugimoto, T.Oka, T.Takahashi, M.Shimizu, Y.Sasaki, R.Hirayama
- Journal Title
  
  Cancer Chemother Pharmacol Epub ahead of print
- Data Source
  KAKENHI-PROJECT-15591437
[Journal Article] Phase I/II study of s-1 combined with irinotecan for metastatic advanced gastric cancer.2006
- Author(s)
  Inokuchi M, Yamashita T, Yamada H, Kojima K, Ichikawa W, Nihei Z, Kawano T, Sugihara K.
- Journal Title
  
  Br J Cancer. May(Epub ahead of print)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591437
[Journal Article] 【各種癌における予後因子と治療効果予測因子】転移性消化器癌における治療効果予測因子2006
- Author(s)
  市川度, 高橋威洋, 須藤謙一, 平山廉三
- Journal Title
  
  Biotherapy 19・3
  
  Pages: 248-254
- Data Source
  KAKENHI-PROJECT-15591437
[Journal Article] Gene expression of ferredoxin reductase predicts outcome in patients with metastatic colorectal cancer treated by 5-fluorouracil plus leucovorin.2006
- Author(s)
  W.Ichikawa, A.Ooyama, E.Toda, Y.Sugimoto, T.Oka, T.Takahashi, M.Shimizu, Y.Sasaki, R.Hirayama
- Journal Title
  
  Cancer Chemother Pharmacol (Epub ahead of print)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591437
[Journal Article] Predictive profiling of 5-fluorouracil (5-FU) resistance in metastatic colorectal cancer (mCRC)2005
- Author(s)
  W.Ichikawa, T.Takahashi, K.Suto, Y.Okayama, E.Toda, T.Oka, S.Okayama, R.Hirayama
- Journal Title
  
  J Clin Oncol 22・14S
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591437
[Journal Article] Thymidylate synthase and dihyropyrimidine dehydrogenase gene expression in relation to differentiation of gastric cancer2004
- Author(s)
  Ichikawa W, Takahashi T, Suto K, Nihei Z, Shirota Y, Shimizu M, Sasaki Y, Hirayama, R.
- Journal Title
  
  International Journal of Cancer 112
  
  Pages: 967-973
- Data Source
  KAKENHI-PROJECT-15591437
[Journal Article] Thymidylate synthase and dihydropyrimidine dehydrogenase gene expression in relation to differentiation of gastric cancer.2004
- Author(s)
  Ichikawa W, Takahashi T, Suto K, Nihei Z, Shirota Y, Shimizu M, Sasaki Y, Hirayama R.
- Journal Title
  
  Int J Cancer. 20 ; 112(6)
  
  Pages: 967-973
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591437
[Journal Article] Thymidylate synthase predictive power is overcome by irinotecan combination therapy with S-1 for gastric cancer2004
- Author(s)
  Ichikawa W.Takahashi T, Suto K, Yamashita T.Nihei Z, Shirota Y, Shimizu M, Sasaki Y, Hirayama R.
- Journal Title
  
  Birtish Journal of Cancer 95
  
  Pages: 1245-1250
- Data Source
  KAKENHI-PROJECT-15591437
[Journal Article] Thymidylate synthase predictive power is overcome by irinotecan combination therapy with S-1 for gastric cancer.2004
- Author(s)
  Ichikawa W, Takahashi T, Suto K, Yamashita T, Nihei Z, Shirota Y, Shimizu M, Sasaki Y, Hirayama R.
- Journal Title
  
  Br J Cancer. 4 ; 91(7)
  
  Pages: 1245-1250
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591437
[Journal Article] Both gene expression for orotate phosphoribosyltransferase and its ratio to dihydropyrimidine dehydrogenase influence outcome following fluoropyrimidine-based chemotherapy for metastatic colorectal cancer.2003
- Author(s)
  Ichikawa W, Uetake H, Shirota Y, Yamada H, Takahashi T, Nihei Z, Sugihara K, Sasaki Y, Hirayama R.
- Journal Title
  
  Br J Cancer 20 ; 89(8)
  
  Pages: 1486-1492
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591437
[Presentation] Pharmacogenetic profiling and clinical outcome of patients (pts) with advanced gastric cancer (AGC) treated with S-1 monotherapy2007
- Author(s)
  W., Ichikawa, T., Takahashi, Y., Sasaki
- Organizer
  ASCO Meeting Abstracts Jun
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591481

1. NIHEI Zenro (00189341)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. OSANAI Takayuki (50301164)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. HIRAYAMA Renzo (10014317)

# of Collaborated Projects: 2 results

# of Collaborated Products: 13 results
4. 代田喜典 (50322087)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 北郷邦昭 (00161472)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 飯田聡

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Ichikawa Wataru 市川 度

ICHIKAWA Wataru 市川 度

Research Projects

Research Products

Co-Researchers

Development of new system to predict clinical outcome of anti-cancer agent using peripheral lymphocytePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development and clinical application of high-sensitive focused DNA arrayPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Gene analysis in gastric cancer using with laser captured micro-dissectionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies on genomic instability of gastric cancer

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Expression of cancer-specific nuclear matrix protein in gastro-intestinal cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] The Unanswered Question:What is the Determinant of S-1 pharmacokinetics?2008

Author(s)

Journal Title

Data Source

[Journal Article] Re:UGT1A1^*28 genotype and irinotecan-induced neutropenia:dose matters.2008

Author(s)

Journal Title

Data Source

[Journal Article] Re:UGTIAI*28 genotype and irinotecan-induced neutropenia:dose matters2008

Author(s)

Journal Title

Description

Data Source

[Journal Article] The Unanswered Question : What Is the Determinant of S-1 Pharmacokinetics2008

Author(s)

Journal Title

Description

Data Source

[Journal Article] The Unanswered Question:What is the Determinant of S-1 pharmacokinetics2008

Author(s)

Journal Title

Description

Data Source

[Journal Article] CYP2A6 and the plasma level of 5-chloro-2, 4-dihydroxypyridine are determinants of the pharmacokinetic variability of tegafur and 5-fluorouracil, respectively, in Japanese patients with cancer given S-12008

Author(s)

Journal Title

NAID

Description

Data Source

[Journal Article] Re : UGT1A1*28 genotype and irinotecan-induced neutropenia : dose matters2008

Author(s)

Journal Title

Description

Data Source

[Journal Article] Orotate phosphoribosyltransferase gene polymorphism predicts toxicity in patients treated with bolus 5-fluorouracil regimen.2006

Author(s)

Journal Title

Data Source

[Journal Article] 消化器癌の外来化学療法 消化器癌の外来化学療法で用いられる抗悪性腫瘍薬とその特徴2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] Gene expression of ferredoxin reductase predicts outcome in patients with metastatic colorectal cancer treated by 5-fluorouracil plus leucovorin.2006

Author(s)

Ichikawa Wataru 市川度

ICHIKAWA Wataru 市川度

[Journal Article] 消化器癌の外来化学療法消化器癌の外来化学療法で用いられる抗悪性腫瘍薬とその特徴2006

[Journal Article] 消化器癌の外来化学療法消化器癌の外来化学療法のための副作用対策2006

[Journal Article] 【各種癌における予後因子と治療効果予測因子】転移性消化器癌における治療効果予測因子2006