KINOSHITA Hiroyuki 木下浩之

Researcher Number	70291490
Affiliation (Current)	2025: 浜松医科大学, 医学部, 特任研究員 2025: 徳島大学, 大学院医歯薬学研究部(歯学域), 徳島大学専門研究員
Affiliation (based on the past Project Information) *help	2022 – 2024: 浜松医科大学, 医学部, 特任研究員 2022 – 2024: 徳島大学, 大学院医歯薬学研究部(歯学域), 徳島大学専門研究員 2018 – 2023: 徳島大学, 大学院医歯薬学研究部(医学域), 徳島大学専門研究員 2018 – 2019: 徳島大学, 大学院医歯薬学研究部(医学域), 専門研究員 2017: 愛知医科大学, 公私立大学の部局等, 客員研究員 … More 2011 – 2016: 愛知医科大学, 医学部, 教授 2007 – 2011: Wakayama Medical University, 医学部, 准教授 2005 – 2006: 和歌山県立医科大学, 医学部, 助教授 2004: 和歌山県立医科大学, 医学部, 講師 Less
Review Section/Research Field	Principal Investigator Anesthesiology/Resuscitation studies / Basic Section 55050:Anesthesiology-related / Anesthesiology Except Principal Investigator Anesthesiology/Resuscitation studies / Basic Section 55050:Anesthesiology-related / Basic Section 57060:Surgical dentistry-related / Anesthesiology / Surgical dentistry
Keywords	Principal Investigator 記憶 / 麻酔薬 / 循環障害 / 血管内皮機能 / セボフルラン / 脳 / 一酸化窒素 / 麻酔学 / スーパーオキシド / 電気刺激 … More / 不眠 / 婦人科臨床研究 / 妊産婦 / 恐怖記憶 / 精神的ストレス / オートファジー / 血管機能 / 齧歯類 / 血管収縮 / 血管内皮 / 思春期 / Carbon dioxide / Gene knockout mice / Synthase / Nitric oxide / Spinal microarterioles / カリウムチャネル / 脊髄内動脈 / 炭酸ガス / 遺伝子改変動物 / 合成酵素 / 脊髄内微小動脈 / 薬理学 / 驚愕反応 / 揮発性麻酔薬 / 一酸化窒素合成酵素 / 20HETE / NMDA / プロポフォール / 脳スライス / CD34 / 末梢血幹細胞 / 傍動脈神経膠星状細胞 / ナトリウムチャネル / 脳実質内動脈 … More Except Principal Investigator 歯周炎 / 細胞骨格 / 歯周病 / ラット / 体血管抵抗 / 歯周組織炎症 / 血管反応性 / 周術期管理 / トランスレーショナルリサーチ / 高血糖 / 全身炎症性疾患 / 酸化ストレス / 冠動脈内皮細胞 / 全身性炎症性疾患 / 体血管機能 / 術後急性痛 / ビタミンD / 麻酔薬 / プロバイオティクス / 体血管障害 / 歯周炎症 / 血管反応 / 鉄イオン / 鉄代謝 / RNA / 血管内皮細胞 / 冠動脈血管内皮細胞 / 全身疾患 / 血管内日機能 / 血管内皮機能 / IL-17 / miRNA / 内皮機能 / 体血管 / 血管 / 炎症 / 歯周組織 / F-アクチン / 周術期管理学 / イレウス / 消化管筋間神経叢 / パッチクランプ / ヒト神経芽腫細胞 / T型カルシウムチャネル / 細胞死 / ヒト神経芽細胞腫 / 局所麻酔薬 / アンギオテンシン / 高血圧 / 糖尿病 / ペルオキシソーム / 心房筋 / ショック / 頻脈性不整脈 / 全身性炎症症候群 / カリウムチャネル / カルシウムチャネル / チャネル発現 / 活動電位 / 心筋 / 全身性炎症反応症候群 / イオンチャネル / 不整脈 / 敗血症 / ATP感受性カリウムチャネル / アクチン / NADPHオキシダーゼ / 平滑筋 / ヒト血管 / 麻酔学 / 一酸化窒素 / 酸素消費量 / 脳ミトコンドリア / イソフルラン / フリーラジカル / 冠動脈 / セボフルラン / Rho-キナーゼ / 冠勁脈 Less

歯周炎症と体血管障害へのプロバイオティクス及び麻酔薬の効果と細胞骨格制御の役割
- Principal Investigator
  
  川人伸次
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  The University of Tokushima
麻酔術後急性痛におけるビタミンD欠乏の役割と痛み惹起体血管機能異常に関する研究
- Principal Investigator
  
  木村哲朗
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Hamamatsu University School of Medicine
歯周病が惹起する全身炎症性疾患の機序解明と酸化ストレス制御による予防法確立
- Principal Investigator
  
  高石和美
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  The University of Tokushima
The role of immune surveillance system in fear memory constitution and circulatory disturbance according to sleeplessness, and the effects of anestheticsPrincipal Investigator
- Principal Investigator
  
  Kinoshita Hiroyuki
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Hamamatsu University School of Medicine
  The University of Tokushima
細胞骨格およびIL-17制御を介したヒト腎血管内皮機能維持機構の解明と麻酔薬作用
- Principal Investigator
  
  川人伸次
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  The University of Tokushima
Effects of iron metabolism on periodontitis-induced oxidative stress and clinical strategies to improve systemic vascular reactivity
- Principal Investigator
  
  TAKAISHI Kazumi
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  The University of Tokushima
Circulatory derangement resulting from mental stress and the modification caused by anestheticsPrincipal Investigator
- Principal Investigator
  
  KINOSHITA Hiroyuki
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  The University of Tokushima
Elucidation of the intracellular signaling pathway with the cytoskeleton turnover control agents and the effect of anesthetics
- Principal Investigator
  
  KAWAHITO Shinji
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology
- Research Institution
  The University of Tokushima
The development of preventives and therapeutics against systemic endothelial dysfunction induced by the periodontal inflammation and the effects of anesthetics to the induced endothelial dysfunction
- Principal Investigator
  
  TAKAISHI Kazumi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  The University of Tokushima
Role of astrocyto in enteric nervous system and effect of anesthetic on enteric nervous system
- Principal Investigator
  
  Hashimoto Atsushi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology
- Research Institution
  Aichi Medical University
Elucidation of molecular mechanisms of the anesthetic action regarding fear memory constitutionPrincipal Investigator
- Principal Investigator
  
  Kinoshita Hiroyuki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Anesthesiology
- Research Institution
  Aichi Medical University
Role of astrocyte metabolism in the constitution of long-term memory and the molecular pharmacological effect of anestheticsPrincipal Investigator
- Principal Investigator
  
  KINOSHITA Hiroyuki
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Aichi Medical University
臓器血管収縮弛緩におけるペルオキシソーム増殖因子活性化受容体の役割と麻酔薬の影響
- Principal Investigator
  
  角谷哲也
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Wakayama Medical University
Mechanisms of oxidative stress in the human arteries from patients with metabolic syndrome and the treatment using a gene therapy
- Principal Investigator
  
  IRANAMI Hiroshi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Wakayama Medical University
Effects of septic condition on pacemaking cell.-Anti-arrhythmic strategy by gene-based treatments-
- Principal Investigator
  
  HATAKEYAMA Noboru
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Aichi Medical University
  University of Toyama
Analysis of cerebral microcirculatory regulation in relation to anesthetics and gene therapy using the live-cell imagingPrincipal Investigator
- Principal Investigator
  
  KINOSHITA Hiroyuki
- Project Period (FY)
  2007 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Wakayama Medical University
ヒト末梢血幹細胞による血管再生に及ぼす酸化ストレスの影響と麻酔薬作用に関する研究Principal Investigator
- Principal Investigator
  
  木下浩之
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Wakayama Medical University
The analysis of coronary arterial vasospasm using the live-cell imaging in genetically modified pigs and effects of anesthetics
- Principal Investigator
  
  HATANO Yoshio
- Project Period (FY)
  2005 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Wakayama Medical University
ミトコンドリア機能を介する脳虚血耐性の分子化学的解明と麻酔薬作用に関する研究
- Principal Investigator
  
  畑埜義雄
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Wakayama Medical University
神経シグナル伝達を介する中枢神経微小循環の電気薬理的解明と麻酔薬作用に関する研究Principal Investigator
- Principal Investigator
  
  木下浩之
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Wakayama Medical University
The research with genetic engineering regarding the circulatory regulation of spinal microvasculature and the effects of anestheticsPrincipal Investigator
- Principal Investigator
  
  KINOSHITA Hiroyuki
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Wakayama Medical University

[Book] 1. 局所麻酔薬中毒の薬理-B. 心筋と血管平滑筋- 局所麻酔薬中毒・アレルギー2008
- Author(s)
  木下浩之
- Publisher
  克誠堂出版
- Data Source
  KAKENHI-PROJECT-19390409
[Book] 1.局所麻酔薬中毒の薬理-B.心筋と血管平滑筋-局所麻酔薬中毒・アレルギー2008
- Author(s)
  木下浩之
- Publisher
  克誠堂出版
- Data Source
  KAKENHI-PROJECT-19390409
[Journal Article] QTc延長を認めたクレアチントランスポーター欠損症患者の全身麻酔経験2023
- Author(s)
  江口　覚、高田真里菜、篠島　理、西川美佳、髙田　香、藤原茂樹、高石和美、箕田直治、曽我朋宏、木下浩之、川人伸次
- Journal Title
  
  日本小児麻酔学会誌
  
  Volume: 29 Pages: 69-72
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K09219
[Journal Article] Viability of intensive insulin therapy during pediatric surgery2021
- Author(s)
  Soga T, Kawahito S, Mita N, Yagi S, Nitta K, Takata K, Tada F, Kinoshita H, Takaishi K, Kitahata H
- Journal Title
  
  Clinical Pediatric Anesthesia
  
  Volume: 27 Pages: 3-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K09219
[Journal Article] Human vascular smooth muscle function and oxidative stress induced by NADPH oxidase with the clinical implications2021
- Author(s)
  Takaishi K, Kinoshita H, Kawashima S, Kawahito S
- Journal Title
  
  Cells
  
  Volume: 10 Issue: 8 Pages: 1947-1947
- DOI
  10.3390/cells10081947
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09219, KAKENHI-PROJECT-20K10181, KAKENHI-PROJECT-21K08949
[Journal Article] The uterine contraction evaluation is still tricky in the in vivo2021
- Author(s)
  Kinoshita H, Kawahito S
- Journal Title
  
  Journal of Anesthesia
  
  Volume: 33 Issue: 3 Pages: 464-464
- DOI
  10.1007/s00540-021-02919-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09219
[Journal Article] 細胞骨格ターンオーバー調節物質による細胞内経路制御機構の解明と麻酔薬作用2021
- Author(s)
  川人伸次，木下浩之、高石和美、曽我朋宏、八木秀介、北畑　洋
- Journal Title
  
  Precision Medicine
  
  Volume: 4 Pages: 32-35
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K09219
[Journal Article] 細胞骨格およびIL-17制御を介した血管内皮機能維持機構の解明と麻酔薬作用2021
- Author(s)
  川人伸次，高石和美、江口　覚、藤原茂樹、西川美佳、高田真里菜、篠島　理、木下浩之
- Journal Title
  
  BIO Clinica
  
  Volume: 36 Pages: 68-71
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K09219
[Journal Article] Pathophysiology and Complications during Extracorporeal Circulation2020
- Author(s)
  Kawahito Shinji、Soga Tomohiro、Yagi Shusuke、Mita Naoji、Takaishi Kazumi、Kinoshita Hiroyuki、Kitagawa Tetsuya、Kitahata Hiroshi
- Journal Title
  
  J. Med. Invest.
  
  Volume: 67 Issue: 3.4 Pages: 229-235
- DOI
  10.2152/jmi.67.229
- NAID
  130007936865
- ISSN
  1343-1420, 1349-6867
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09219, KAKENHI-PROJECT-20K10181, KAKENHI-PROJECT-19K18245, KAKENHI-PROJECT-18H02888
[Journal Article] Cytoskeleton-disrupting agent cytochalasin B reduces oxidative stress caused by high glucose in the human arterial smooth muscle2020
- Author(s)
  Takaishi Kazumi、Kinoshita Hiroyuki、Feng Guo-Gang、Azma Toshiharu、Kawahito Shinji、Kitahata Hiroshi
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 144 Issue: 4 Pages: 197-203
- DOI
  10.1016/j.jphs.2020.08.004
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09219, KAKENHI-PROJECT-20K09234, KAKENHI-PROJECT-20K10181, KAKENHI-PROJECT-18K08841, KAKENHI-PROJECT-18K08873
[Journal Article] The Clinically Relevant Concentration of Local Anesthetics Is a Matter of Consideration in the In Vitro Study2020
- Author(s)
  Kinoshita Hiroyuki、Kawahito Shinji
- Journal Title
  
  Anesthesia & Analgesia
  
  Volume: 131 Issue: 2 Pages: e86-e86
- DOI
  10.1213/ane.0000000000004894
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09219
[Journal Article] Continuous blood glucose monitoring during pediatric cardiopulmonary bypass2019
- Author(s)
  Kakuta N, Kawahito S, Mita N, Soga T, Yagi S, Satomi S, Tada F, Kinoshita H, Takaishi K, Kitahata H
- Journal Title
  
  Clin Pediatr Anesth
  
  Volume: 25 Pages: 3-7
- NAID
  120006768427
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11082
[Journal Article] Accuracy and reliability of continuous blood glucose monitoring during pediatric cardiopulmonary bypass.2019
- Author(s)
  Kawahito S, Mita N, Soga T, Yagi S, Kakuta N, Satomi S, Kinoshita H, Takaishi K, Kitagawa T, Kitahata H
- Journal Title
  
  Journal of Artificial Organs
  
  Volume: 22 Issue: 4 Pages: 353-356
- DOI
  10.1007/s10047-019-01111-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K18245, KAKENHI-PROJECT-18H02888, KAKENHI-PROJECT-17K11082, KAKENHI-PROJECT-17K11909
[Journal Article] The nessesity to use selective NADPH oxidase inhibitors.2018
- Author(s)
  Satomi S, Kawahito S, Kinoshita H
- Journal Title
  
  J Anesth
  
  Volume: 32 Pages: 914-914
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11082
[Journal Article] Airway obstruction caused by acute transient thyroid swelling following fine needle aspiration biopsy of thyroid gland2018
- Author(s)
  橋本篤、木下浩之、磯部英男、榊原健介、藤田義人、畠山登、藤原祥裕
- Journal Title
  
  Journal of the Japanese Society of Intensive Care Medicine
  
  Volume: 25 Issue: 3 Pages: 195-196
- DOI
  10.3918/jsicm.25_195
- NAID
  130006731115
- ISSN
  1340-7988, 1882-966X
- Year and Date
  2018-05-01
- Language
  Japanese
- Data Source
  KAKENHI-PROJECT-15K10548
[Journal Article] The Unknown Mechanism of Exogenous Tetrahydrobiopterin in the Renal Protection of Sheep Ischemia and Reperfusion2018
- Author(s)
  Kinoshita Hiroyuki、Otake Kazunobu、Yamasaki Takashi
- Journal Title
  
  Anesthesia & Analgesia
  
  Volume: 126 Issue: 3 Pages: 1088-1088
- DOI
  10.1213/ane.0000000000002784
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10548
[Journal Article] The unique action of nicorandil on cerebral circulation2018
- Author(s)
  Kinoshita Hiroyuki、Kawahito Shinji、Takaishi Kazumi
- Journal Title
  
  Journal of Anesthesia
  
  Volume: 32 Issue: 3 Pages: 1-1
- DOI
  10.1007/s00540-018-2499-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10548, KAKENHI-PROJECT-17K11909, KAKENHI-PROJECT-17K11910
[Journal Article] Will stroke volume variation be a parameter to manage intraoperative bleeding in the functional endoscopic sinus surgery.2018
- Author(s)
  Kinoshita H, Kawahito S
- Journal Title
  
  Minerva Anesthesiol
  
  Volume: 84 Pages: 1235-1236
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11082
[Journal Article] The unique action of nicorandil on cerebral circulation2018
- Author(s)
  Kinoshita H, Kawahito S, Takaishi K
- Journal Title
  
  J Anesth
  
  Volume: 32 Pages: 462-462
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11082
[Journal Article] Phosphatidylinositol 3-kinase inhibition induces vasodilator effect of sevoflurane via reduction of Rho kinase activity.2017
- Author(s)
  Miyamoto Y, Feng GG, Satomi S, Tanaka K, Fujiwara Y, Kinoshita H.
- Journal Title
  
  Life Sci.
  
  Volume: 177 Pages: 20-26
- DOI
  10.1016/j.lfs.2017.04.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10998, KAKENHI-PROJECT-15K10548
[Journal Article] Tissue oxygenation index reflects changes in forearm blood flow after brief ischemia2017
- Author(s)
  Kinoshita Hiroyuki、Akahori Takahiko、Nakamura Emi、Okawa Hazuki、Kawahito Shinji、Kitahata Hiroshi、Fujiwara Yoshihiro
- Journal Title
  
  J. Med. Invest.
  
  Volume: 64 Issue: 3.4 Pages: 228-232
- DOI
  10.2152/jmi.64.228
- NAID
  130006105185
- ISSN
  1343-1420, 1349-6867
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11909, KAKENHI-PROJECT-17K11910
[Journal Article] Human serum albumin and oxidative stress in preeclamptic women and the mechanism of albumin for stress reduction2017
- Author(s)
  Kinoshita Hiroyuki、Watanabe Kazushi、Azma Toshiharu、Feng Guo-Gang、Akahori Takahiko、Hayashi Hisaki、Sato Motohiko、Fujiwara Yoshihiro、Wakatsuki Akihiko
- Journal Title
  
  Heliyon
  
  Volume: 3 Issue: 8 Pages: e00369-e00369
- DOI
  10.1016/j.heliyon.2017.e00369
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10979, KAKENHI-PROJECT-15K10548, KAKENHI-PROJECT-15K10998
[Journal Article] Successful treatment of mixed (mainly cancer) pain by tramadol preparations2017
- Author(s)
  Kawahito S, Soga T, Mita N, Satomi S, Kinoshita H, Arase T, Kondo A, Miki H, Takaishi K, Kitahata H
- Journal Title
  
  J Med Invest
  
  Volume: 64 Pages: 311-312
- NAID
  130006105167
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11082
[Journal Article] Successful treatment of mixed (mainly cancer) pain by tramadol preparations2017
- Author(s)
  Kawahito S, Soga T, Mita N, Satomi S, Kinoshita H, Arase T, Miki H, Takaishi K, Kitahata H
- Journal Title
  
  J. Med. Invest.
  
  Volume: 64 Issue: 3.4 Pages: 311-312
- DOI
  10.2152/jmi.64.311
- NAID
  130006105167
- ISSN
  1343-1420, 1349-6867
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K11910, KAKENHI-PROJECT-16K20102
[Journal Article] Involvement of superoxide generated by NADPH oxidase in the shedding of procoagulant vesicles from human monocytic cells exposed to bupivacaine2017
- Author(s)
  Azma Toshiharu、Ogawa Saori、Nishioka Akira、Kinoshita Hiroyuki、Kawahito Shinji、Nagasaka Hiroshi、Matsumoto Nobuyuki
- Journal Title
  
  Journal of Thrombosis and Thrombolysis
  
  Volume: 44 Issue: 3 Pages: 341-354
- DOI
  10.1007/s11239-017-1531-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10979, KAKENHI-PROJECT-15K10548, KAKENHI-PROJECT-16K15684
[Journal Article] Tissue oxygenation index reflects changes in forearm blood flow after brief ischemia2017
- Author(s)
  Kinoshita H, Akahori T, Nakakura E, Okawa H, Kawahito S, Kitahata H, Fujiwara Y
- Journal Title
  
  J Med Invest
  
  Volume: 64 Pages: 228-232
- NAID
  130006105185
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11082
[Journal Article] Involvement of superoxide generated by NADPH oxidase in the shedding of precoagulant vesicles from human monocytic cells exposed to bupivacaine2017
- Author(s)
  Azma T, Ogawa S, Nishioka A, Kinoshita H, Kawahito S, Nagasaka H, Matsumoto N
- Journal Title
  
  J Thromb Thrombolysis
  
  Volume: 44 Pages: 341-354
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11082
[Journal Article] Does Memory Consolidation by Anesthetics Relate to a Time Window of Age?2017
- Author(s)
  Kinoshita Hiroyuki
- Journal Title
  
  Anesthesia & Analgesia
  
  Volume: 125 Issue: 1 Pages: 357-357
- DOI
  10.1213/ane.0000000000002163
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10548, KAKENHI-PROJECT-15K15575
[Journal Article] Sevoflurane inhalation accelerates the long-term memory consolidation via small GTPase overexpression in the hippocampus of mice in adlescence.2016
- Author(s)
  Nakamura E, Kinoshita H, Feng GG, Hayashi H, Satomoto M, Fujiwara Y.
- Journal Title
  
  PloS One.
  
  Volume: 11 Issue: 9 Pages: e0163151-e0163151
- DOI
  10.1371/journal.pone.0163151
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K10998, KAKENHI-PROJECT-16K08508, KAKENHI-PROJECT-16K08600, KAKENHI-PROJECT-15K15575
[Journal Article] Role of ion channels in sepsis-induced atrial tachyarrhythmias in guinea pigs2012
- Author(s)
  Aoki Y, Hatakeyama N, Yamamoto S, Kinoshita H, Matsuda N, Hattori Y, Yamazaki M
- Journal Title
  
  Br J Pharmacol
  
  Volume: 166 Issue: 1 Pages: 390-400
- DOI
  10.1111/j.1476-5381.2011.01769.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592001, KAKENHI-PUBLICLY-23122506
[Journal Article] 酸化ストレスからみた臓器保護:心不全と酸化ストレス2011
- Author(s)
  木下浩之
- Journal Title
  
  日本臨床麻酔学会雑誌 31
  
  Pages: 116-123
- NAID
  10027753115
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390409
[Journal Article] 酸化ストレスからみた臓器保護:心不全と酸化ストレス2011
- Author(s)
  木下浩之
- Journal Title
  
  日本臨床麻酔学会誌
  
  Volume: 31 Pages: 116-123
- NAID
  10027753115
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591985
[Journal Article] 高血糖病態が血管平滑筋機能に及ぼす影響2011
- Author(s)
  木下浩之
- Journal Title
  
  循環制御
  
  Volume: 32 Pages: 3-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591985
[Journal Article] 『静脈麻酔薬の作用機序:受容体と細胞内シグナル伝達機構』プロポフォール2011
- Author(s)
  木下浩之
- Journal Title
  
  Anesthesia 21 Century 2011 13
  
  Pages: 4-10
- Data Source
  KAKENHI-PROJECT-19390409
[Journal Article] 酸化ストレスからみた臓器保護:心不全と酸化ストレス2011
- Author(s)
  木下浩之
- Journal Title
  
  日本臨床麻酔学会雑誌
  
  Volume: 31 Pages: 116-123
- NAID
  10027753115
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591985
[Journal Article] 『静脈麻酔薬の作用機序:受容体と細胞内シグナル伝達機構』プロポフォール2011
- Author(s)
  木下浩之
- Journal Title
  
  Anesthesia 21 Century
  
  Volume: 13 Pages: 4-10
- Data Source
  KAKENHI-PROJECT-21591985
[Journal Article] The modulation of vascular ATP-sensitive K^+channel function via phosphatidylinosito 3-kinase-Akt pathway activated by phenylephrine2010
- Author(s)
  Haba M, Hatakeyama N, Kinoshita H, Teramae H, Azma T, Hatano Y, Matsuda N
- Journal Title
  
  J Pharmacol Exp Ther
  
  Volume: 334 Pages: 673-678
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591985
[Journal Article] The modulation of vascular ATP-sensitive K^+ channel function via phosphatidylinositol 3-kinase-Akt pathway activated by phenylephrine.2010
- Author(s)
  Haba M, Hatakeyama N, Kinoshita H, Teramae H, Azma T, Hatano Y, Matsuda N
- Journal Title
  
  J Pharmacol Exp Ther 334
  
  Pages: 673-678
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390409
[Journal Article] ホスファチジルイノシトール3-キナーゼ-Akt 経路と血管病態生理2010
- Author(s)
  木下浩之
- Journal Title
  
  Anesthesia 21 Century 12
  
  Pages: 2309-2316
- Data Source
  KAKENHI-PROJECT-19390409
[Journal Article] ホスファチジルイノシトール3-キナーゼ-Akt経路と血管病態生理2010
- Author(s)
  木下浩之
- Journal Title
  
  Anesthesia 21 Century
  
  Volume: 12 Pages: 2309-2316
- Data Source
  KAKENHI-PROJECT-21591985
[Journal Article] 周術期不整脈の管理と治療全身性炎症反応症候群(SIRS)と頻脈性不整脈、その治療戦略2010
- Author(s)
  畠山登, 青木優太, 木下浩之, 寺前洋生, 松田直之, 山崎光章
- Journal Title
  
  日本臨床麻酔学会誌
  
  Volume: 30巻5号 Pages: 765-770
- Data Source
  KAKENHI-PROJECT-21592001
[Journal Article] 高血糖による生体侵襲2009
- Author(s)
  木下浩之
- Journal Title
  
  救急・集中治療 20
  
  Pages: 1177-1180
- Data Source
  KAKENHI-PROJECT-21591985
[Journal Article] 血管への酸化ストレスと麻酔薬2009
- Author(s)
  木下浩之
- Journal Title
  
  麻酔
  
  Volume: 58
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591985
[Journal Article] The role of 20-hydroxyeicosatetraenoic acid in cerebral arteriolar constriction and the inhibitory effect of propofol2009
- Author(s)
  Hama-Tomioka K, Kinoshita H, Azma T, Nakahata K, Matsuda N, Hatakeyama N, Kikuchi H, Hatano Y
- Journal Title
  
  Anesth Analg 109
  
  Pages: 1935-1942
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390409
[Journal Article] Pharmacological significance of the blocking action of the intravenous general an esthetic propofol on the slow component of cardiac delayed rectifier K+ current.2009
- Author(s)
  Hatakeyama N, Sakuraya F, Matsud a N, Kimura J, Kinoshita H, Kemmotsu O, Yamazaki M, Hattori Y.
- Journal Title
  
  J Pharmacol Sci 110
  
  Pages: 334-343
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592001
[Journal Article] Pharmacological significance of the blocking action of the intravenous general anesthetic propofol on the slow component of cardiac delayed rectifier K+current2009
- Author(s)
  Hatakeyama N, Sakuraya F, Matsuda N, Kimura J, Kinoshita H, Kemmotsu O, Yamazaki M, Hattori Y
- Journal Title
  
  J Pharmacol Sci. 2009 Jul
  
  Volume: 110(3) Pages: 334-43
- NAID
  10025737753
- Data Source
  KAKENHI-PROJECT-21592001
[Journal Article] The beneficial effect of propofol on arterial adenosine triphosphate-sensitive K^+ channel function impaired by thromboxane2009
- Author(s)
  Haba M, Kinoshita H, Matsuda N, Azma T, Hama-Tomioka K, Hatakeyama N, Yamazaki M, Hatano Y
- Journal Title
  
  Anesthesiology 111
  
  Pages: 279-286
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390409
[Journal Article] The beneficial effect of propofol on arterial adenosine triphosphate-sensitive K^+channel function impaired by thromboxane2009
- Author(s)
  Haba M, Kinoshita H, Matsuda N, Azma T, Hama-Tomioka K, Hatakeyama N, Yamazaki M, Hatano Y
- Journal Title
  
  Anesthesiology
  
  Volume: 111 Pages: 279-286
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591985
[Journal Article] 血管への酸化ストレスと麻酔薬2009
- Author(s)
  木下浩之
- Journal Title
  
  麻酔 58
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390409
[Journal Article] The role of 20-hydroxyeicosatetraenoic acid in cerebral arteriolar constriction and the inhibitory effect of propofol.2009
- Author(s)
  Hama-Tomioka K, Kinoshita H, Azma T, Nakahata K, Matsuda N, Hatakeyama N, Kikuchi H, Hatano Y
- Journal Title
  
  Anesth Analg 109
  
  Pages: 1935-1942
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390409
[Journal Article] The role of 20-hydroxyeicosatetraenoic acid in cerebral arteriolar constriction and the inhibitory effect of propofol2009
- Author(s)
  Hama-Tomioka K, Kinoshita H, et al.
- Journal Title
  
  Anesth Analg 109
  
  Pages: 1935-1942
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390409
[Journal Article] The beneficial effect of propofol on arterial adenosine triphosphate-sensitive K^+ channel function impaired by thromboxane.2009
- Author(s)
  Haba M, Kinoshita H, Matsuda N, Azma T, Hama-Tomioka K, Hatakeyama N, Yamazaki M, Hatano Y
- Journal Title
  
  Anesthesiology 111
  
  Pages: 279-286
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390409
[Journal Article] Choiinesterase inhibitor donepeziJ dilates cerebral parenehymal arterioles via the activation of neuroual nitric oxide synthase2008
- Author(s)
  Nakahata K, Kinoshita H, Hama-Tomioka K, Ishida Y, Matsuda N, Haiakeyama N, Haba M. Kondo T, Hatano Y
- Journal Title
  
  Anesthesiology 109
  
  Pages: 124-129
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390432
[Journal Article] Propofol restores brain microvascular function impaired by high glucose via the decrease in oxidative stress.2008
- Author(s)
  Nakahata K, Kinoshita H, Azma T, Matsuda N, Hama-Tomioka K, Haba M, Hatano Y
- Journal Title
  
  Anesthesiology 108
  
  Pages: 269-275
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390409
[Journal Article] Cholinesterase inhibitor donepezil dilates cerebral parenchymal arterioles via the activation of neuronal nitric oxide synthase2008
- Author(s)
  Nakahata K, Kinoshita H, Hama-Tomioka K, Ishida Y, Matsuda N, Hatakeyama N, Haba M, Kondo T, Hatano Y
- Journal Title
  
  Anesthesiology 109
  
  Pages: 124-129
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390409
[Journal Article] Roles of PI3K-Akt and NADPH oxidase in ATP-sensitive K^+ channel function impaired by high glucose in the human artery.2008
- Author(s)
  Kinoshita H, Matsuda N, et al.
- Journal Title
  
  Hypertension 52
  
  Pages: 507-513
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18659462
[Journal Article] Cholinesterase inhibitor donepezil dilates cerebral parenchyma1 arterioles via the activation of neuronal nitric oxide synthase.2008
- Author(s)
  Nakahata K, Kinoshita H, et al.
- Journal Title
  
  Anesthesiology 109
  
  Pages: 124-129
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390409
[Journal Article] Cholinesterase inhibitor donepezil dilates cerebral parenchymal arterioles via the activation of neuronal nitric oxide synthase.2008
- Author(s)
  Nakahata K, Kinoshita H, et al.
- Journal Title
  
  Anesthesiology 109
  
  Pages: 124-129
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18659462
[Journal Article] Propofol restores brain microvascular function impaired by high glucose via the decrease in oxidative stress2008
- Author(s)
  Nakahata K, Kinoshita H, Azma T, Matsuda N, Hama-Tomioka K, Haba M, Hatano Y
- Journal Title
  
  Anesthesiology 108
  
  Pages: 269-275
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390409
[Journal Article] Roles of PI3K-Akt and NADPH oxidase in ATP-sensitive F^+ channe1 function impaired by high glucose in the human artery.2008
- Author(s)
  Kinoshita H, Matsuda N, et al.
- Journal Title
  
  Hypertension 52
  
  Pages: 507-513
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390409
[Journal Article] Cholinesterase inhibitor donepezil dilates cerebral parenchymal arterioles via the activation of neuronal nitric oxide synthase.2008
- Author(s)
  Nakahata K, Kinoshita H, Hama-Tomioka K, Ishida Y, Matsuda N, Hatakeyama N, Haba M, Kondo T, Hatano Y
- Journal Title
  
  Anesthesiology 109
  
  Pages: 124-129
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390409
[Journal Article] Propofol restores brain microvascular function impaired by high glucose via the decrease in oxidative stress.2008
- Author(s)
  Nakahata K, Kinoshita H, et al.
- Journal Title
  
  Anesthesiology 108
  
  Pages: 269-275
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390409
[Journal Article] Propofol restores brain microvascular function impaired by high glucose via the decrease in oxidative stress.2008
- Author(s)
  Nakahata K, Kinoshita H, et al.
- Journal Title
  
  Anesthesiology 108
  
  Pages: 269-275
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18659462
[Journal Article] Propofol restores brain microvascular function impaired by high glucose via the decrease in oxidative stress2008
- Author(s)
  Nakahata K, Kinoshita H, Azma T, Matsuda N, Hama-Tomioka K, Haba M, Hatano Y
- Journal Title
  
  Anesthesiology 108
  
  Pages: 269-275
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390432
[Journal Article] Sevoflurane,but not propofol,prevents Rho kinase-dependent contraction induced by sphingosylphosphorylcholine in the porcine coronary artery.2007
- Author(s)
  Kinoshita H, Matsuda N, Kimoto Y, Tohyama S, Hama K, Nakahata K, Hatano Y
- Journal Title
  
  Anesthesia and Analgesia 105
  
  Pages: 325-329
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390409
[Journal Article] Sevoflurane, but not propofol, prevents Rho kinaso-depcndenl contraction induced by sphingosylphosphorylcholino in theporcine coronary artery2007
- Author(s)
  Kinoshita H, Matsuda N, Kimoto Y, Tohyama S, Hama K, Nakahata K, Hatano Y
- Journal Title
  
  Anesth Analg 105
  
  Pages: 325-329
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390432
[Journal Article] Sevoflurane,but not propofol,prevents Rho kinase-dependent contraction induced by sphingosylphosphorylcholine in the porcine coronary artery.2007
- Author(s)
  Kinoshita H, Matsuda N, Kimoto Y, Tohyama S, Hama K, Nakahata K, Hatano Y
- Journal Title
  
  Anesthesia and Analgesia 105
  
  Pages: 325-329
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390432
[Journal Article] Sevoflurane,but not propofol,prevents Rho kinase-dependent contraction induced by sphingosylphosphorylcholine in the porcine coronary artery.2007
- Author(s)
  Kinoshita H, Matsuda N, Kimoto Y, Tohyama S, Hama K, Nakahata K, Hatano Y
- Journal Title
  
  Anesthesia and Analgesia 105
  
  Pages: 325-329
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18659462
[Journal Article] Augmented activity of adenosine triphosphate-sensitive K^+ channels induced by droperidol in the rat aorta2006
- Author(s)
  Kinoshita H, Dojo M, Nakahata K, Kimoto Y, Kakutani T, Mizumoto K, Hatano Y
- Journal Title
  
  Anesthesia and Analgesia 102
  
  Pages: 786-791
- Data Source
  KAKENHI-PROJECT-18659462
[Journal Article] Vasodilation mediated by inward rectifier K^+ channels in cerebral microvessels of hypertensive and normotensive rats2006
- Author(s)
  Nakahata K, Kinoshita H, Tokinaga Y, Ishida V, Kimoto Y, Dojo M, Mizumoto K, Ogawa K, Hatano Y
- Journal Title
  
  Anesth Analg 102
  
  Pages: 571-576
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390432
[Journal Article] Vasodilation mediated by inward rectifier K^+ channels in cerebral microvessels of hypertensive and normotensive rats2006
- Author(s)
  Nakahata K, Kinoshita H, Tokinaga Y, Ishida Y, Kimoto Y, Dojo M, Mizumoto K, Ogawa K, Hatano Y
- Journal Title
  
  Anesthesia and Analgesia 102
  
  Pages: 571-576
- Data Source
  KAKENHI-PROJECT-16659426
[Journal Article] Augmented activity of adenosine triphosphate-sensitive K^+ channels induced by droperidol in the rat aorta2006
- Author(s)
  Kinoshita H, Dojo M, Nakahata K, Kimoto Y, Kakutani T, Mizumoto K, Hatano Y
- Journal Title
  
  Anesthesia and Analgesia 102
  
  Pages: 786-791
- Data Source
  KAKENHI-PROJECT-17390432
[Journal Article] Synthetic peroxisome proliferator-activated receptor-γ agonists restore impaired vasorelaxation via ATP-sensitive K^+ channels by high glucose.2006
- Author(s)
  Kinoshita H, Azma T, Iranami H, Nakahata K, Kimoto Y, Dojo M, Yuge O, Hatano Y
- Journal Title
  
  Journal of Pharmacology and Experimental Therapeutics 318
  
  Pages: 1-7
- Data Source
  KAKENHI-PROJECT-17390432
[Journal Article] Vasodilation mediated by inward rectifier K^+ channels in cerebral microvessels of hypertensive and normotensive rats2006
- Author(s)
  Nakahata K, Kinoshita H, Tokinaga Y, Ishida Y, Kimoto Y, Dojo M, Mizumoto K, Ogawa K, Hatano Y
- Journal Title
  
  Anesthesia and Analgesia 102
  
  Pages: 571-576
- Data Source
  KAKENHI-PROJECT-16390458
[Journal Article] Augumented activity of adenosine triphosphate-sensitive K^+ channels induced by droperiodol in the rat aorta2006
- Author(s)
  Kinoshita H, Dojo M, Nakahata K, Kimoto Y, Kakutani T, Misumoto K, Hatano Y
- Journal Title
  
  Anesthesia and Analgesia 102
  
  Pages: 786-791
- Data Source
  KAKENHI-PROJECT-17390432
[Journal Article] Augmented activity of adenosine triphosphate-sensitive K^+ channels induced by droperidol in the rat aorta2006
- Author(s)
  Kinoshita H, Dojo M, Nakahata K, Kimoto A, Kakutani T, Mizumoto K, Hatano Y
- Journal Title
  
  Anesthesia and Analgesia 102
  
  Pages: 786-791
- Data Source
  KAKENHI-PROJECT-17659493
[Journal Article] Synthetic peroxisome proliferator-activated receptor-γ agonists restore impaired vasorelaxation via ATP-sensitive K^+ channels by high glucose2006
- Author(s)
  Kinoshita H, Azma T, Iranami H, Nakahata K, Kimoto Y, Dojo M, Yuge O, Hatano Y
- Journal Title
  
  Journal of Pharmacology and Experimental Therapeutics 318
  
  Pages: 1-7
- Data Source
  KAKENHI-PROJECT-18659462
[Journal Article] Vasodilation mediated by inward rectifier K^+ channels in cerebral microvessels of hypertensive and normotensive rats2006
- Author(s)
  Nakahata K, Kinoshita H, Tokinaga Y, Ishida Y, Kimoto Y, Dojo M, Mizumoto K, Ogawa K, Hatano Y
- Journal Title
  
  Anesthesia and Analgesia 102
  
  Pages: 571-576
- Data Source
  KAKENHI-PROJECT-17659493
[Journal Article] Synthetic pcroxisome prolifcrator-activated rpceptptor-γ agonists retome impaired vasorlaxation via ATP sensitive K' channels by high glucose, J Pharmacol Exp Ther2006
- Author(s)
  Kinoshita H, Azma T, Iranami H, Nakahata K, Kiraoto Y, Do jo M, Yuge 0, Hatano Y
- Journal Title
  
  318
- Data Source
  KAKENHI-PROJECT-17390432
[Journal Article] Synthetic peroxisome proliferator-activated receptor-γ agonists restore impaired vasorelaxation via ATP-sensitive K^+ channels by high glucose.2006
- Author(s)
  Kinoshita H, Azma T, Iranami H, Nakahata K, Kimoto Y, Dojo M, Yuge O, Hatano Y
- Journal Title
  
  Journal of Pharmacology and Experimental Therapeutics 318
  
  Pages: 1-7
- Data Source
  KAKENHI-PROJECT-16390458
[Journal Article] Augmented activity of adenosine triphosphate-sensitive K^+ channels induced by droperidol in the rat aorta2006
- Author(s)
  Kinoshita H, Dojo M, Nakahata K, Kimoto Y, Kakutani T, Mizumoto K, Hatano Y
- Journal Title
  
  Anesthesia and Analgesia 102
  
  Pages: 786-791
- Data Source
  KAKENHI-PROJECT-16390458
[Journal Article] Vasodilation mediated by inward rectifier K^+ channels in cerebral microvessels of hypertensive and normotensive rats2006
- Author(s)
  Nakahata K, Kinoshita H, Tokinaga Y, Ishida Y, Kimoto Y, Dojo M, Mizumoto K, Ogawa K, Hatano Y
- Journal Title
  
  Anesthesia and Analgesia 102
  
  Pages: 571-576
- Data Source
  KAKENHI-PROJECT-17390432
[Journal Article] Augmented activity of adenosine triphosphate-sensitive K^+ channels induced by droperidol in the rat aorta2006
- Author(s)
  Kinoshita H, Dojo M, Nakahata K, Kimoto Y, Kakutani T, Mizumoto K, Hatano Y
- Journal Title
  
  Anesthesia and Analgesia 102
  
  Pages: 786-791
- Data Source
  KAKENHI-PROJECT-17659493
[Journal Article] Augmented activity of adenosine triphosphate-sensitive K^+ channels induced by droperidol in the rat aorta2006
- Author(s)
  Kinoshita H, Dojo M, Nakahata K, Kimoto Y, Kakutani T, Mizumoto K, Hatano Y
- Journal Title
  
  Anesth Analg 102
  
  Pages: 786-791
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390432
[Journal Article] Vasodi lation mediated by inward rectifier K^+ channels in cerebral microvessels of hypertensive and normotensive rats2006
- Author(s)
  Nakahata K, Kinoshita H, Tokinaga Y, Ishida Y, Kimoto Y, Dojo M, Mizumoto K, Ogawa K, Hatano Y
- Journal Title
  
  Anesthesia and Analgesia 102
  
  Pages: 571-576
- Data Source
  KAKENHI-PROJECT-16390458
[Journal Article] Synthetic peroxisome proliferator-activated receptor-γ agonists restore impaired vasorelaxation via ATP-sensitive K^+ channels by high glucose2006
- Author(s)
  Kinoshita H, Azma T, Iranami H, Nakahata K, Kimoto Y, Dojo M, Yuge O, Hatano Y
- Journal Title
  
  Journal of Pharmacology and Experimental Therapeutics 318
  
  Pages: 1-7
- Data Source
  KAKENHI-PROJECT-17659493
[Journal Article] Augmented activity of adenosine triphosphate-sensitive K^+ channels induced by droperidol in the rat aorta2006
- Author(s)
  Kinoshita H, Dojo M, Nakahata K, Kimoto Y, Kakutani T, Mizumoto K, Hatano Y
- Journal Title
  
  Anesthesia and Analgesia 102
  
  Pages: 786-791
- Data Source
  KAKENHI-PROJECT-16659426
[Journal Article] Vasodilation mediated by inward rectifier K^+ channels in cerebral microvessels of hypertensive and normotensive rats2006
- Author(s)
  Nakahata K, Kinoshita H, Tokinaga Y, Ishida Y, Kimoto Y, Dojo M, Mizumoto K, Dgawa K, Hatano Y
- Journal Title
  
  Anesthesia and Analgesia 102
  
  Pages: 571-576
- Data Source
  KAKENHI-PROJECT-17659493
[Journal Article] Vasodilation mediated by inward rectifier K^+ channels in cerebral microvessels of hypertensive and normotensive rats.2006
- Author(s)
  Nakahata K, Kinoshita H, Tokinaga Y, Ishida Y, Kimoto Y, Dojo M, Mizumoto K, Ogawa K, Hatano Y
- Journal Title
  
  Anesth Analg 102
  
  Pages: 571-576
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390458
[Journal Article] Vasodilation mediated by inward rectifier K^+ channels in cerebral microvessels of hypertensive and normotensive rats2006
- Author(s)
  Nakahata K, Kinoshita H, Tokinaga Y, Ishida Y, Kimoto Y, Dojo M, Mizumoto K, Ogawa K, Hatano Y
- Journal Title
  
  Anesthesia and Analgesia 102
  
  Pages: 571-576
- Data Source
  KAKENHI-PROJECT-18659462
[Journal Article] Augmented activity of adenosine triphosphate-sensitive K^+ channels induced by droperidol in the rat aorta.2006
- Author(s)
  Kinoshita H, Dojo M, Nakahata K, Kimoto Y, Kakutani T, Mizumoto K, Hatano Y
- Journal Title
  
  Anesth Analg 102
  
  Pages: 786-791
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390458
[Journal Article] The inhibitory effects of lidocaine and mexiletine on vasorelaxation mediated by adenosine triphosphate-sensitive K^+ channels and the role of kinases in the porcine coronary artery2005
- Author(s)
  Kimoto Y, Kinoshita H, Nakahata K, Dojo M, Hatano Y
- Journal Title
  
  Anesthesiology 102
  
  Pages: 581-587
- Data Source
  KAKENHI-PROJECT-17659493
[Journal Article] The inhibitory effects of lidocaine and mexiletine on vasorelaxation mediated by adenosine triphosphate-sensitive K^+ channels and the role of kinases in the porcine coronary artery2005
- Author(s)
  Kimoto Y, Kinoshita H, Nakahata K, Dojo M, Hatano Y
- Journal Title
  
  Anesthesiology 102
  
  Pages: 581-587
- Data Source
  KAKENHI-PROJECT-16390458
[Journal Article] The inhibitory effects of lidocaine and mexiletine on vasorelaxation mediated by adenosine triphosphate-sensitive K^+ channels and the role of kinases in the porcine coronary artery.2005
- Author(s)
  Kimoto Y, Kinoshita H, Nakahata K, Dojo M, Hatano Y
- Journal Title
  
  Anesthesiology 102
  
  Pages: 581-587
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390458
[Journal Article] The inhibitory effects of lidocaine and mexiletine on vasorelaxation mediated by adenosine triphosphate-sensitive K^+ channels and the role of kinases in the porcine coronary artery2005
- Author(s)
  Kimoto Y, Kinoshita H, Nakahata K, Dojo M, Hatano Y
- Journal Title
  
  Anesthesiology 102
  
  Pages: 581-587
- Data Source
  KAKENHI-PROJECT-16659426
[Journal Article] The inhibitory effects of lidocaine and mexiletine on vasorelaxation mediated by adenosine triphosphate-sensitive K^+ channels and the role of kinases in the porcine coronary artery2005
- Author(s)
  Kimoto Y, Kinoshita H, Nakahata K, Dojo M, Hatano Y
- Journal Title
  
  Anesthesiology 102
  
  Pages: 581-587
- Data Source
  KAKENHI-PROJECT-17390432
[Journal Article] Effects of bupivacaine enantiomers and ropivacaine on vasorelaxation mediated by adenosine triphosphate-sensitive K^+ channels in the rat aorta2004
- Author(s)
  Dojo M, Kinoshita H, Nakahata K, Kimoto Y, Hatano Y
- Journal Title
  
  Anesthesiology 101
  
  Pages: 251-254
- Data Source
  KAKENHI-PROJECT-16390458
[Journal Article] Inhibitory effect of high concentration of glucose on relaxations to activation of ATP-sensitive K^+ channels in human omental artery2004
- Author(s)
  Kinoshita H, Azma T, Nakahata K, Iranami H, Kimoto Y, Dojo M, Yuge O, Hatano Y
- Journal Title
  
  Arteriosclerosis, Thrombosis, and Vascular Biology 24
  
  Pages: 1-6
- Data Source
  KAKENHI-PROJECT-16390458
[Journal Article] Effects of bupivacaine enantiomers and ropivacaine on vasorelaxation mediated by adenosine triphosphate-sensitive K^+ channels in the rat aorta2004
- Author(s)
  Dojo M, Kinoshita H, Nakahata K, Kimoto Y, Hatano Y
- Journal Title
  
  Anesthesiology 101
  
  Pages: 251-254
- Data Source
  KAKENHI-PROJECT-16659426
[Journal Article] Inhibitory effect of high concentration of glucose on relaxations to activation of ATP-sensitive K^+ channels in human omental artery.2004
- Author(s)
  Kinoshita H, Azma T, Nakahata K, Iranami H, Kimoto Y, Dojo M, Yuge O, Hatano Y
- Journal Title
  
  Arterioscler Thromb Vasc Biol 24
  
  Pages: 1-6
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390458
[Journal Article] Lidocaine impairs vasodilation mediated by adenosine triphosphate-sensitive K^+ channels but not by inward rectifier K^+ channels in parenchymal microvessels of rat cerebral cortex2004
- Author(s)
  Kinoshita H, Nakahata K, Dojo M, Kimoto Y, Hatano Y
- Journal Title
  
  Anesthesia and Analgesia 99
  
  Pages: 904-909
- Data Source
  KAKENHI-PROJECT-16390458
[Journal Article] Lidocaine impairs vasodilation mediated by adenosine triphosphate-sensitive K^+ channels but not by inward rectifier K^+ channels in parenchymal microvessels of rat cerebral cortex.2004
- Author(s)
  Kinoshita H, Nakahata K, Dojo M, Kimoto Y, Hatano Y
- Journal Title
  
  Anesth Analg 99
  
  Pages: 904-909
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390458
[Journal Article] Effects of bupivacaine enantiomers and ropivacaine on vasorelaxation mediated by adenosine triphosphate-sensitive K^+ channels in the rat aorta.2004
- Author(s)
  Dojo M, Kinoshita H, Nakahata K, Kimoto Y, Hatano Y
- Journal Title
  
  Anesthesiology 101
  
  Pages: 251-254
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390458
[Journal Article] Vascular effects of antiarrhythmic drugs and the roles of K+ channels2004
- Author(s)
  Kinoshita H, Hatano Y
- Journal Title
  
  Current Medicinal Chemistry-Cardiovascular and Hematological Agents 2
  
  Pages: 99-106
- Data Source
  KAKENHI-PROJECT-16659426
[Journal Article] Vascular effects of antiarrhythmic drugs and the roles of K+ channels2004
- Author(s)
  Kinoshita H, Hatano Y
- Journal Title
  
  Current Medicinal Chemistry-Cardiovascular and Hematological Agents 2
  
  Pages: 99-106
- Data Source
  KAKENHI-PROJECT-16390458
[Journal Article] Inhibitory effect of high concentration of glucose on relaxations to activation of ATP-sensitive K^+ channels in human omental artery2004
- Author(s)
  Kinoshita H, Azma T, Nakahata K, Iranami H, Kimoto Y, Dojo M, Yuge O, Hatano Y
- Journal Title
  
  Arteriosclerosis, Thrombosis, and Vascular Biology 24
  
  Pages: 1-6
- Data Source
  KAKENHI-PROJECT-16659426
[Journal Article] Lidocaine impairs vasodilation mediated by adenosine triphosphate-sensitive K^+ channels but not by inward rectifier K^+ channels in parenchymal microvessels of rat cerebral cortex2004
- Author(s)
  Kinoshita H, Nakahata K, Dojo M, Kimoto Y, Hatano Y
- Journal Title
  
  Anesthesia and Analgesia 99
  
  Pages: 904-909
- Data Source
  KAKENHI-PROJECT-16659426
[Presentation] 複数回の再手術を要した血友病Bの1症例2022
- Author(s)
  高田真里菜、西川美佳、篠島理、藤原茂樹、高石和美、江口覚、箕田直治、高田香、曽我朋宏、木下浩之、川人伸次
- Organizer
  第43回日本循環制御医学会総会
- Data Source
  KAKENHI-PROJECT-20K09219
[Presentation] 下咽頭梨状窩瘻に対し化学的焼灼術を施行した1症例2022
- Author(s)
  篠島理、高田真里菜、西川美佳、藤原茂樹、高石和美、江口覚、箕田直治、高田香、曽我朋宏、木下浩之、川人伸次
- Organizer
  第43回日本循環制御医学会総会
- Data Source
  KAKENHI-PROJECT-20K09219
[Presentation] 心肺蘇生時におけるクアドラライト麻酔用マスクの有用性の検討2022
- Author(s)
  西川美佳、高田真里菜、篠島理、藤原茂樹、高石和美、江口覚、箕田直治、高田香、曽我朋宏、木下浩之、川人伸次
- Organizer
  第43回日本循環制御医学会総会
- Data Source
  KAKENHI-PROJECT-20K09219
[Presentation] 帝王切開術時の臨床的羊水塞栓により子宮摘出術を施行した症例2019
- Author(s)
  曽我朋宏、川人伸次、高田　香、牧野佐和、新田一仁、木下浩之、高石和美、北畑　洋
- Organizer
  第40回日本循環制御医学会総会
- Data Source
  KAKENHI-PROJECT-17K11082
[Presentation] Pleth Variability Index Predicts Hemodynamic Derangements in Patients Undergoing Oral Surgery2019
- Author(s)
  Kazumi Takaishi, Tomohiro Aoyama, Shigeki Fujiwara, Rho Otsuka, Satoru Eguchi, Yasuo M Tsutsumi, Shinji Kawahito, Hiroyuki Kinoshita, Hiroshi Kitahata
- Organizer
  2019 Annual Meeting of American Society of Anesthesiologists (ASA)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11082
[Presentation] Pleth variability index predicts hemodynamic derangements in patients undergoing oral surgery.2019
- Author(s)
  Takaishi K, Aoyama T, Fujiwara S, Otsuka R, Eguchi S, Tsutsumi Y, Kawahito S, Kinoshita H, Kitahata H
- Organizer
  The Anesthesiology 2019 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11910
[Presentation] 脱血管挿入部の逢着のため肺動脈カテーテル抜去困難となり開胸下抜去術が必要になった症例2018
- Author(s)
  箕田直治、板東悠太郎、里見志帆、曽我朋宏、富山芳信、木下浩之、川人伸次、田中克哉、高石和美、北畑　洋
- Organizer
  第39回日本循環制御医学会
- Data Source
  KAKENHI-PROJECT-17K11082
[Presentation] 臨床使用濃度のセボフルランはトロンボキサン収縮ラット血管でのプロテインキナーゼC活性化を介して内皮機能を抑制する2018
- Author(s)
  里見志帆、川人伸次、高石和美、曽我朋宏、箕田直治、北畑　洋、田中克哉、木下浩之
- Organizer
  第39回日本循環制御医学会
- Data Source
  KAKENHI-PROJECT-17K11082
[Presentation] TEEガイド下に開胸心筋生検術を施行した転移性心臓腫瘍の症例2018
- Author(s)
  箕田直治、里見志帆、木下浩之、川人伸次、北畑　洋、田中克哉
- Organizer
  第24回日本心臓血管麻酔学会
- Data Source
  KAKENHI-PROJECT-17K11082
[Presentation] The role of F-actin constitution in oxidative stress caused by high glucose in the human artery2018
- Author(s)
  Shiho Satomi, Kazumi Takaishi, Shinji Kawahito, Hiroshi Kitahata, Katsuya Tanaka, Hiroyuki Kinoshita
- Organizer
  American Society of Anesthesiologists Annual meeting 2018
- Data Source
  KAKENHI-PROJECT-17K11910
[Presentation] The role of F-actin constitution in oxidative stress caused by high glucose in the human artery2018
- Author(s)
  Shiho Satomi, Kazumi Takaishi, Shinji Kawahito, Hiroshi Kitahata, Katsuya Tanaka, Hiroyuki Kinoshita
- Organizer
  2018 Annual Meeting of American Society of Anesthesiologists (ASA)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11082
[Presentation] Rapamycin becomes the sevoflurane vasodilator effect apparent in the rat artery2018
- Author(s)
  Kazumi Takaishi, Shiho Satomi, Naoji Mita, Takeshi Yamamoto, Ryo Otsuka, Satoru Eguchi, Shigeki Joseph Luke Fujiwara, Shinji Kawahito, Hiroyuki Kinoshita, Hiroshi Kitahata
- Organizer
  The 15th International Dental Congress on Anesthesia, Sedation and Pain Control
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11910
[Presentation] 重症大動脈弁狭窄症患者の非心臓手術について2017
- Author(s)
  里見志帆、川人伸次、曽我朋宏、箕田直治、高石和美、北畑　洋、木下浩之、田中克哉
- Organizer
  第38回日本循環制御医学会
- Data Source
  KAKENHI-PROJECT-17K11082
[Presentation] Roles of clinical sevoflurane doses as both the protein kinase C activator and NADPH oxidase inhibitor upon thrombokane A2 application in the rat arteries2017
- Author(s)
  Satomi S, Takaishi K, Kawahito S, Kitahata H, Tanaka K, Kinoshita H
- Organizer
  American Society of Aneshthesiologists
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11910
[Presentation] Roles of clinical sevoflurane doses as both the protein kinase C activator and NADPH oxidase inhibitor upon thromboxane A2 application in the rat arteries2017
- Author(s)
  Shiho Satomi, Kazumi Takaishi, Shinji Kawahito, Horoshi Kitahata, Katsuya Tanaka, Hiroyuki Kinoshita
- Organizer
  2017 Annual Meeting of American Society of Anesthesiologists (ASA)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11082
[Presentation] 周術期における組織間質液中グルコース濃度連続測定システムと人工膵臓の血糖精度比較2017
- Author(s)
  常城あゆみ、木下倫子、箕田直治、曽我朋宏、角田奈美、川人伸次
- Organizer
  第54回中国・四国麻酔科学会
- Data Source
  KAKENHI-PROJECT-17K11082
[Presentation] マイクロカフ小児用気管チューブの使用経験2017
- Author(s)
  曽我朋宏、川人伸次、牧野佐和、新田一仁、木下浩之、多田文彦、川人伸次
- Organizer
  第23回日本小児麻酔学会
- Data Source
  KAKENHI-PROJECT-17K11082
[Presentation] 常温血性心筋保護液持続冠灌流による開心術の麻酔経験2017
- Author(s)
  里見志帆、笠井飛鳥、木下浩之、川人伸次、田中克哉
- Organizer
  第38回日本循環制御医学会
- Data Source
  KAKENHI-PROJECT-17K11082
[Presentation] 若年成体マウスへのセボフルラン暴露は恐怖記憶定着を促進する2015
- Author(s)
  中村絵美、橋本篤、ハロッド美佐子、椋田崇、藤原祥裕、木下浩之
- Organizer
  日本麻酔科学会第62回学術集会
- Place of Presentation
  兵庫県神戸市
- Year and Date
  2015-05-28
- Data Source
  KAKENHI-PROJECT-15K15575
[Presentation] 酸化ストレスが血管反応に及ぼす作用と麻酔薬2011
- Author(s)
  木下浩之
- Organizer
  日本麻酔科学会第58回学術集会
- Place of Presentation
  兵庫県神戸市
- Data Source
  KAKENHI-PROJECT-21591985
[Presentation] Isoflurane protects ATP-sensitive K^+channels from oxidativ e stress caused by high glucose in the human artery2011
- Author(s)
  Kinoshita H, Matsuda N, Iranami H, Azma T, Yamazaki M
- Organizer
  2011 Annual Meeting of American Society of Anesthesiologist
- Place of Presentation
  Chicago, IL, USA
- Data Source
  KAKENHI-PROJECT-21591985
[Presentation] イソフルランは高濃度ブドウ糖による酸化ストレスからヒトATP感受性カリウムチャネル機能を保護する2011
- Author(s)
  木下浩之、松田直之、東俊晴、畠山登、伊良波浩、山崎光章
- Organizer
  日本麻酔科学会第58回学術集会
- Place of Presentation
  兵庫県神戸市
- Data Source
  KAKENHI-PROJECT-21591985
[Presentation] Roles of oxidative stress and propofol in cerebral microvessel dilation via NMDA receptors.2010
- Author(s)
  Hama-Tomioka K, Kinoshita H, Nakahata K, Hatakeyama N, Hatano Y
- Organizer
  2010 Annual Meeting of American Society of Anesthesiologist
- Place of Presentation
  San Diego, CA, USA
- Data Source
  KAKENHI-PROJECT-19390409
[Presentation] 高濃度ブドウ糖で抑制されたヒト大網動脈ATP感受性カリウムチャネル機能に及ぼす細胞骨格制御の効果2010
- Author(s)
  木下浩之、松田直之、東俊晴、畠山登、中畑克俊、畑埜義雄
- Organizer
  日本麻酔科学会第57回学術集会
- Place of Presentation
  福岡県福岡市
- Data Source
  KAKENHI-PROJECT-21591985
[Presentation] Isoflurane protects human ATP-sensitive K^+channels from oxidative stress induced by high glucose2010
- Author(s)
  Kinoshita H, Matsuda N, Hatakeyama N, Iranami H, Hatano Y
- Organizer
  2010 Annual Meeting of American Society of Anesthesiologist
- Place of Presentation
  San Diego, CA, USA
- Data Source
  KAKENHI-PROJECT-21591985
[Presentation] Roles of oxidative stress and propofol in cerebral microvessel dilation via NMDA receptors2010
- Author(s)
  Hama-Tomioka K, Kinoshita H, Nakahata K, Hatakeyama N, Hatano Y
- Organizer
  2010 Annual Meeting of American Society of Anesthesiologist
- Place of Presentation
  San Diego, CA, USA
- Data Source
  KAKENHI-PROJECT-19390409
[Presentation] Isoflurane protects human ATP-sensitive K^+ channels from oxid ative stress induced by high glucose2010
- Author(s)
  Kinoshita H, Matsuda N, Hatakeyama N, Iranami H, Hatano Y
- Organizer
  2010 Annual Meeting of American Society of Anesthesiologist
- Place of Presentation
  San Diego
- Data Source
  KAKENHI-PROJECT-21591985
[Presentation] The role of NMDA receptors in rat cerebral microvessel dilation and the inhibitory effect of propofol2010
- Author(s)
  Hama-Tomioka K, Kinoshita H, Hatano H
- Organizer
  2010 Annual Meeting of the International Anesthesia Research Society
- Place of Presentation
  Honolulu, Hawaii, USA
- Data Source
  KAKENHI-PROJECT-19390409
[Presentation] The Role of Cytoskeleton in Vascular ATP-Sensitive K^+Channel Function Modified by High Glucose2009
- Author(s)
  Kinoshita H, Hatakeyama N, Hatano Y
- Organizer
  2009 Annual Meeting of American Society of Anesthesiologist
- Place of Presentation
  New Orleans, LA
- Data Source
  KAKENHI-PROJECT-21591985
[Presentation] The Role of Cytoskeleton in Vascular ATP-Sensitive K^+ Channel Function Modified by High Glucose2009
- Author(s)
  Hiroyuki Kinoshita, et al.
- Organizer
  Annual Meeting of American Society of Anesthesiologist
- Place of Presentation
  New Orleans, LA, USA
- Data Source
  KAKENHI-PROJECT-21591985
[Presentation] The Role of Superoxide in 20-HETE-Induced Vasoconstriction and the Effect of Propofol in the Brain2009
- Author(s)
  Kinoshita H, Hatakeyama N, Hatano Y
- Organizer
  Annual Meeting of American Society of Anesthesiologist
- Place of Presentation
  New Orleans, LA, USA
- Data Source
  KAKENHI-PROJECT-19390409
[Presentation] The Role of Superoxide in 20-HETE-Induced Vasoconstriction and the Effect of Propofol in the Brain2009
- Author(s)
  Kinoshita H, Hatakeyama N, Hatano Y
- Organizer
  2009 Annual Meeting of American Society of Anesthesiologist
- Place of Presentation
  New Orleans, LA, USA
- Data Source
  KAKENHI-PROJECT-19390409
[Presentation] The inhibitory effect of propofol on the cerebral microvessel function via neurovascular coupling2008
- Author(s)
  Hama-Tomioka k, Kinoshita H, Nakahata K, Hatakeyama N, Hatano Y
- Organizer
  Annual Meeting of American Society of Anesthesiologist
- Place of Presentation
  Orlando, FL, USA
- Data Source
  KAKENHI-PROJECT-19390409
[Presentation] 鳥濃度ブドウ糖はフォスソファチジルイノシトール3キナーゼを介しヒト大網動脈ATP感受性カリウムチャネルを抑制する2008
- Author(s)
  木下浩之, 松川直之, 中畑克俊, 丹下和晃, 富岡恵子, 畑埜義雄
- Organizer
  日本麻酔科学会第55回学術集会
- Place of Presentation
  神奈川県横浜市
- Data Source
  KAKENHI-PROJECT-17390432
[Presentation] 電気刺激で引き起こされるラット脳実質内細動脈の収縮及び拡張反応2008
- Author(s)
  富岡恵子, 木下浩之, 中畑克俊, 中田亮子, 畑埜義雄
- Organizer
  日本麻酔科学会第55回学術集会
- Place of Presentation
  神奈川県横浜市
- Data Source
  KAKENHI-PROJECT-17390432
[Presentation] ヒト血管平滑筋における高血糖のNADPH oxidaseの活性訓節作用2008
- Author(s)
  松田直之, 蒲ひかり, 内御堂亮, 木下浩之, 畑埜義雌
- Organizer
  日本麻酔科学会第55回学術集会
- Place of Presentation
  神奈川県横浜市
- Data Source
  KAKENHI-PROJECT-17390432
[Presentation] The role of 20-HETE in the cerebral microvessel function as consequences of neurovascular coupling2008
- Author(s)
  Hama-Tomioka K, Kinoshita H, Nakahata K, Hatakeyama N, Hatano Y
- Organizer
  Annual Meeting of American Society of Anesthesiologist
- Place of Presentation
  Orlando, FL, USA
- Data Source
  KAKENHI-PROJECT-19390409
[Presentation] The role of PI3K-Akt in human vascular ATP-sensi tive K^+ channel function modified by high glucose.2008
- Author(s)
  Kinoshita H, et al
- Organizer
  Annual Meeting of American Society of Anest hesiologist
- Place of Presentation
  Orlando, FL, USA
- Data Source
  KAKENHI-PROJECT-19390409
[Presentation] The role of PI3K-Akt in human vascular ATP-sensitive K^+ channel function modified by high glucose.2008
- Author(s)
  Kinoshita H, et al
- Organizer
  Annual Meeting of American Society of Anest hesiologist
- Place of Presentation
  Orlando, FL, USA
- Data Source
  KAKENHI-PROJECT-18659462
[Presentation] 電気刺激で引き起こされるラット脳実質内細動脈の収縮及び拡張反応2008
- Author(s)
  富岡恵子, 木下浩之, 畑埜義雄
- Organizer
  第29回日本循環制御医学会総会
- Place of Presentation
  神奈川県横浜市
- Year and Date
  2008-05-11
- Data Source
  KAKENHI-PROJECT-17390432
[Presentation] 血管平滑筋ATP感受性カリウムチャネル機能に及ぼすホスファチジルイノシトール3キナーゼ活性の影響2008
- Author(s)
  羽場政法, 木下浩之, 畠山登, 根来孝明, 畑埜義雄
- Organizer
  第29回日本循環制御医学会総会
- Place of Presentation
  神奈川県横浜市
- Year and Date
  2008-05-01
- Data Source
  KAKENHI-PROJECT-17390432
[Presentation] コリンエステラ一ゼ阻害薬ドネベジルによる神経型一駿化窒素合成酵素を介したラット脳細動脈拡帳反応2008
- Author(s)
  中畑克俊, 羽場政法, 濱恵子, 堂城真友了, 木下浩之, 畑埜義雌
- Organizer
  日本麻酔科学会第55回学術集会
- Place of Presentation
  神奈川県横浜市
- Data Source
  KAKENHI-PROJECT-17390432
[Presentation] The role of 20-HETE in the cerebral microvessel function as consequences of neurovascular coupling2008
- Author(s)
  Hama-Tomioka K, Kinoshita H, Nakahata K, Hatakeyama N, Hatano Y
- Organizer
  2008 Annual Meeting of American Society of Anesthesiologist
- Place of Presentation
  Orlando, FL, USA
- Data Source
  KAKENHI-PROJECT-19390409
[Presentation] 血管平滑筋ATP感受性カリウムチャネル機能に及ぼすホスファチジルイノシトー3キナーゼ活性の影響2008
- Author(s)
  羽場政法, 濱恵子, 中畑克俊, 畠山登, 木下浩之, 畑埜義雄
- Place of Presentation
  神奈川県横浜市
- Data Source
  KAKENHI-PROJECT-17390432
[Presentation] The inhibitory effect of propofol on the cerebral microvessel function via neurovascular coupling2008
- Author(s)
  Hama-Tomioka k, Kinoshita H, Nakahata K, Hatakeyama N, Hatano Y
- Organizer
  2008 Annual Meeting of American Society of Anesthesiologist
- Place of Presentation
  Orlando, FL, USA
- Data Source
  KAKENHI-PROJECT-19390409
[Presentation] べルオキシゾーム増殖剤応答性受容体作用薬の抗酸化作用とヒト大網動脈のATP感受性カリウムチャネル活性2007
- Author(s)
  木下浩之, 東俊晴, 伊良波浩, 中畑克俊, 堂城真友子, 畑埜義雄
- Organizer
  日本麻酔科学会第54回学術集会
- Place of Presentation
  北海道札幌市
- Data Source
  KAKENHI-PROJECT-17390432
[Presentation] Constriction Followed by Dilation of Cerebral Microvessels as Consequences of Neurovascular Coupling2007
- Author(s)
  Hama-Tomioka K, Kinoshita H, Nakahata K, Nakata R, Hatano Y
- Organizer
  Annual Meeting of American Society of Anesthesiologist
- Place of Presentation
  San Francisco, CA, USA
- Data Source
  KAKENHI-PROJECT-19390409
[Presentation] ブロボフォ一ルは高濃度ブドウ糖で抑制されたラット脳微小動脈拡張反応を回復させる2007
- Author(s)
  中畑克俊, 木下浩之, 長谷川愛, 澤恵子, 畑埜義雄
- Organizer
  日本麻酔科学会第54回学術集会
- Place of Presentation
  北海道札幌市
- Data Source
  KAKENHI-PROJECT-17390432
[Presentation] Donepezil Dukates Cercgral Parenchymal Arterioles Via Activation of Neuronal Nitric Oxide Synthase2007
- Author(s)
  Katsutoshi Nakahata, Hiroyuki Kinoshita, Ai Ishikawa, You Sakanaka, Yoshio Hatano
- Organizer
  Annual Meeting of American Society of Anesthesiologist
- Place of Presentation
  San Francisco, CA, TSA
- Data Source
  KAKENHI-PROJECT-17390432
[Presentation] 電気刺激で引き起こされるラット脳実質内細動脈の収縮及び拡張反応2007
- Author(s)
  濱恵子, 木下浩之, 吉村聖子, 阪中容, 畑埜義雄
- Organizer
  日本麻酔科学会第54回大会
- Place of Presentation
  北海道札幌市
- Data Source
  KAKENHI-PROJECT-17390432
[Presentation] Propofol Ameliorates Brain Microvaeclar Function Impaired by High Glucoswed Via Anti OxidativeEffect2007
- Author(s)
  Katsutoshi Nakahara, Hiroyuki Kinoshita, Yoko Setou, Tetsuya Kakutani, Yoshio Hatano
- Organizer
  Annual Meeting of American Society of Anesthesiologist
- Place of Presentation
  San Francisco, CA, USA
- Data Source
  KAKENHI-PROJECT-17390432
[Presentation] Constriction Followed by Dilation of Cerebral Microvessels as Consequences of Neurovascular Coupling2007
- Author(s)
  Hama-Tomioka K, Kinoshita H, Nakahata K, Nakata R, Hatano Y
- Organizer
  2007 Annual Meeting of American Society of Anesthesiologist
- Place of Presentation
  San Francisco, CA, USA
- Data Source
  KAKENHI-PROJECT-19390409
[Presentation] セボフルランはRhoキナーゼ活性化を介するブタ冠動脈収縮を抑制するがプロポフォールは抑制しない2006
- Author(s)
  木本吉紀, 木下浩之, 堂城真友子, 中畑克俊, 畑埜義雄
- Organizer
  日本麻酔科学会第53回大会
- Place of Presentation
  兵庫県神戸市
- Year and Date
  2006-06-13
- Data Source
  KAKENHI-PROJECT-17390432
[Presentation] 温度変化がATP感受性カリウムチャネルを介するラット大動脈の弛緩反応に及ぼす影響2006
- Author(s)
  堂城真友子, 木下浩之, 平野勇生, 濱恵子, 畑埜義雄
- Organizer
  日本麻酔科学会第53同大会
- Place of Presentation
  兵庫県神戸市
- Data Source
  KAKENHI-PROJECT-17390432
[Presentation] 高濃度ブドウ糖で抑制されたヒト大網動脈のATP感受性カリウムチャネル活性に及ぼすペルオキシゾーム増殖剤応答性受容体リガンドの効果2006
- Author(s)
  木下浩之, 中畑克俊, 堂城真友子, 木本古紀, 畑埜義雄
- Organizer
  第27回日本循環制御医学会総会
- Place of Presentation
  東京都港区
- Data Source
  KAKENHI-PROJECT-17390432
[Presentation] プロポフォールは高濃度ブドウ糖で抑制されたラット脳微小血管拡張反応を回復させる2006
- Author(s)
  中畑克俊, 木下浩之, 堂城真友子, 丹下和晃, 畑埜義雄
- Organizer
  日本麻酔科学会第53回大会
- Place of Presentation
  兵庫県神戸市
- Year and Date
  2006-06-13
- Data Source
  KAKENHI-PROJECT-17390432
[Presentation] 高濃度ブドウ糖がATP感受性カリウムチャネルを介するヒト動脈弛緩に及ぼす作用とスーパーオキシドの関与2006
- Author(s)
  木下浩之, 中畑克俊, 畑埜義雄
- Organizer
  第33回日本集中治療医学会学術集会
- Place of Presentation
  大阪府大阪市
- Year and Date
  2006-03-24
- Data Source
  KAKENHI-PROJECT-17390432
[Presentation] 温度変化がATP感受性カリウムチャネルを介するラット大動脈の弛緩反応に及ぼす影響2006
- Author(s)
  堂城真友子, 木下浩之, 木本吉紀, 中畑克俊, 畑埜義雄
- Organizer
  第27回日本循環制御医学会総会
- Place of Presentation
  東京都港区
- Data Source
  KAKENHI-PROJECT-17390432
[Presentation] 高濃度ブドウ糖で抑制されたヒト大網動脈のATP感受性カリウムチャネル活性に及ぼすペルオキシゾーム増殖剤応答性受容体リガンドの効果2006
- Author(s)
  木下浩之, 中畑克俊, 木本吉紀, 堂城真友子, 伊良波浩, 畑埜義雄
- Organizer
  日本麻酔科学会第53回大会
- Place of Presentation
  兵庫県神戸市
- Data Source
  KAKENHI-PROJECT-17390432
[Presentation] プロポフォールは高濃度グルコースによるラット脳微小血管拡張の抑制作用を改善する2006
- Author(s)
  中畑克俊, 木下浩之, 堂城真友子, 木本吉紀, 畑埜義雄
- Organizer
  第27回日本循環制御医学会総会
- Place of Presentation
  東京都港区
- Data Source
  KAKENHI-PROJECT-17390432
[Presentation] 高濃度にブドウ糖がATP感受性カリウムチャネルを介するヒト動脈弛緩反応に及ぼす作用とスーパーオキシドの関与2006
- Author(s)
  木下浩之, 木本吉紀, 畑埜義雄, 東俊晴,伊良波浩, 弓削孟文
- Organizer
  日本麻酔科学会第52回学術集会
- Place of Presentation
  兵庫県神戸市
- Data Source
  KAKENHI-PROJECT-17390432
[Presentation] アルツハイマー治療薬ドネペジルによる一酸化窒素合成酵素を介したラット脳実質内細動脈拡張反応2006
- Author(s)
  中畑克俊, 大森亜紀, 伊良波浩, 木下浩之, 畑埜義雄, 前田浩
- Organizer
  日本麻酔科学会第52回学術集会
- Place of Presentation
  兵庫県神戸市
- Data Source
  KAKENHI-PROJECT-17390432
[Presentation] ドロペリドールがATP感受性カリウムチャネルを介するラット大動脈弛緩反応に及ぼす作用2006
- Author(s)
  堂城貞友子, 木下浩之木木吉紀, 岩橋静江,畑埜義雄
- Organizer
  日本麻酔科学会第52回学術集会
- Place of Presentation
  兵庫県神戸市
- Data Source
  KAKENHI-PROJECT-17390432
[Presentation] アミオダロンがATP感受性カリウムチャネルを介するヒト大網動脈の弛緩反応に及ぼす作用2005
- Author(s)
  木下浩之, 中畑克俊, 畑埜義雄
- Organizer
  第32回日本集中治療医学会学術集会
- Place of Presentation
  東京都新宿区
- Data Source
  KAKENHI-PROJECT-17390432
[Presentation] 高濃度ブドウ糖がATP感受性カリウムチャネルを介するヒト大綱動脈弛緩反応に及ぼす作用とPKCの関与2005
- Author(s)
  木下浩之, 中畑克俊, 畑埜義雄
- Organizer
  第32回日本集中治療医学会学術集会
- Data Source
  KAKENHI-PROJECT-17390432
[Presentation] 箕西利之, 畑埜義雄,Rhoキナーゼ活性薬によるブタ冠動脈収縮反応に対するセボンルランの抑制効果2005
- Author(s)
  木本吉紀, 木下浩之, 堂城真友了,箕西利之, 畑埜義雄
- Organizer
  日本麻酔科学会第52回学術集会
- Place of Presentation
  兵庫県神戸市
- Data Source
  KAKENHI-PROJECT-17390432
[Presentation] 若年成体マウスへのセボフルラン暴露は恐怖記憶定着を促進する
- Author(s)
  中村絵美、橋本篤、ハロッド美佐子、椋田崇、藤原祥裕、木下浩之
- Organizer
  日本麻酔科学会第62回学術集会
- Place of Presentation
  兵庫県神戸市
- Year and Date
  2015-05-28 – 2015-05-30
- Data Source
  KAKENHI-PROJECT-24659703
[Presentation] P13K-Dependent Reduction od ATP-Sensitive K^+ Channel Function by High Glucose in the Human Arterym
- Author(s)
  Hiroyuki Kinoshita, Naoyuki Matsuda, Hikari Kaba, Katsutoshi Nakahata, Yoshio Hatano
- Organizer
  Annual Meeting of American Society of Anesthesiologist
- Place of Presentation
  San Francisco, CA, USA
- Data Source
  KAKENHI-PROJECT-17390432
[Presentation] Constriction Followed by Dilation of Cerebral Microvessels as Consequonres of Neurovascular Coupling
- Author(s)
  Keiko Hama-Tomioka, Hiroyuki Kinoshita, Katsutoshi Nakahata, Ryoko Nakata, Yoshio Hatano
- Organizer
  Annual Meeting of American Society of Anesthesiologist
- Place of Presentation
  San Francisco, CA, USA
- Data Source
  KAKENHI-PROJECT-17390432
[Presentation] Sevoflurane inhalation accelerates the long-term horror learning ability in young adult mice.
- Author(s)
  Kinoshita H, Nakamura E, Feng G-G, MD, Li J, Jiang J, Sakakibara K, Fujiwara Y
- Organizer
  Annual Meeting of American Society of Anesthesiologist
- Place of Presentation
  New Orleans, LA, USA
- Year and Date
  2014-10-11 – 2014-10-15
- Data Source
  KAKENHI-PROJECT-24659703

1. KAWAHITO Shinji (60284296)

# of Collaborated Projects: 8 results

# of Collaborated Products: 33 results
2. HATANO Yoshio (70115913)

# of Collaborated Projects: 6 results

# of Collaborated Products: 93 results
3. TAKAISHI Kazumi (20325286)

# of Collaborated Projects: 6 results

# of Collaborated Products: 23 results
4. 北畑洋 (60161486)

# of Collaborated Projects: 5 results

# of Collaborated Products: 18 results
5. 渡辺員支 (80281187)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
6. 水本弘 (50239258)

# of Collaborated Projects: 3 results

# of Collaborated Products: 10 results
7. HATAKEYAMA Noboru (70251907)

# of Collaborated Projects: 3 results

# of Collaborated Products: 11 results
8. 工藤保誠 (50314753)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
9. NAKAHATA Katsutoshi (70332971)

# of Collaborated Projects: 2 results

# of Collaborated Products: 34 results
10. MATSUDA Naoyuki (50332466)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
11. IRANAMI Hiroshi (30193692)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
12. AZMA Toshiharu (60284197)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
13. AOKI Yuta (10621667)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
14. YAMAMOTO Seiji (10456361)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
15. NARITA Minoru (40318613)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. Hashimoto Atsushi (00378035)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. Feng Guo-Gang (70351111)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
18. 中畑克俊 (00405416)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 角谷哲也 (00264896)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 田中克哉 (30263841)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 中島芳樹 (00252198)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 江口覚 (20263866)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 藤原茂樹 (90434505)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 木村哲朗 (00467250)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 湯本浩通 (60284303)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 毛利安宏 (80464353)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. Nishioka Akira

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
28. 箕田直治

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KINOSHITA Hiroyuki 木下 浩之

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The role of immune surveillance system in fear memory constitution and circulatory disturbance according to sleeplessness, and the effects of anestheticsPrincipal Investigator

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Circulatory derangement resulting from mental stress and the modification caused by anestheticsPrincipal Investigator

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Elucidation of molecular mechanisms of the anesthetic action regarding fear memory constitutionPrincipal Investigator

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Role of astrocyte metabolism in the constitution of long-term memory and the molecular pharmacological effect of anestheticsPrincipal Investigator

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KINOSHITA Hiroyuki 木下浩之