HIROMI Yasushi 広海健

Researcher Number	70291888
Other IDs
External Links
Affiliation (based on the past Project Information) *help	1997 – 2011: 国立遺伝学研究所, 個体遺伝研究系, 教授 2007: National Institute of Genetics, 個体遣伝研究系, 教授
Review Section/Research Field	Principal Investigator Biological Sciences / Developmental biology / Developmental biology Except Principal Investigator Developmental biology / Biological Sciences
Keywords	Principal Investigator ショウジョウバエ / Seven-up / 神経幹細胞 / 転写因子 / 光受容ニューロン / 神経発生 / 核内リセプター / 転写因子スイッチング / seven-up / 神経芽細胞 … More / COUP-TF / Sprouty / 運命決定 / 複眼 / MAPKシグナル伝達経路 / cell fate decision / photoreceptor neuron / nuclear rectptor / Drosophila / 構造-機能関係 / 異所発現 / リガンド結合領域 / ニューロン運命決定 / Polycombグループ / Polyhomeotic / 核内レセプター / SAMドメイン / TFIIH / 細胞運命 / ガイダンス分子 / Netrin / Unc5 / ネトリン / 軸索誘導 / 軸索ガイダンス分子 / 細胞運命決定 / Notchシグナル / NGB / グリア / 転写因子Seven-up / ショウジョウバェ / 細胞周期 / Krupped / Hunchback / 細胞幹細胞 / 転写抑制 / Argos / Sprauty / serev-up / 転写 / 光受容細胞 / グリア細胞 / 幹細胞プログラム / rasシグナル / 神経細胞 / ets型転写因子 / ras / ニューロン / homeogenetic inductionn / 伸展受容器 / 誘導調節 / FGFシグナリング / EGFシグナリング / P-因子 / ETS蛋白 / 気管形成 / RAS / パターン形成 … More Except Principal Investigator ショウジョウバエ / 感覚器 / 卵巣 / 始原生殖細胞 / 生殖細胞 / 幹細胞ニッチ / 幹細胞 / 発生 / ボディープラン / Cut / 運命決定 / 神経系 / primordial germ cell / ovary / Drosophila / germ cells / stem cell niche / stem cells / 生殖幹細胞 / RNAi / atonal / dpp / 目 / 神経 / 進化 / 転写因子 / 位置情報 / cut遺伝子 / bHLH型転写因子 Less

Presentation and suppression of axon guidance molecules by their receptors : a new principle of axon guidancePrincipal Investigator
- Principal Investigator
  
  HIROMI Yasushi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Developmental biology
- Research Institution
  National Institute of Genetics
転写因子SEVEN-UPによる遺伝子発現プログラムのスイッチングPrincipal Investigator
- Principal Investigator
  
  広海健
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  National Institute of Genetics
Analysis of mechanisms underlying stem cell fate determination in Drosophila germline
- Principal Investigator
  
  ASAOKA Miho
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Developmental biology
- Research Institution
  National Institute of Genetics
ショウジョウバエ神経幹細胞プログラムのdecodingPrincipal Investigator
- Principal Investigator
  
  広海健
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  National Institute of Genetics
Functional analysis of genes required for germline-stem-cell niche formation in Drosophila ovary
- Principal Investigator
  
  ASAOKA Miho
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Developmental biology
- Research Institution
  National Institute of Genetics
ショウジョウバエにおける生殖幹細胞ニッチの形成機構とシグナル分子の探索
- Principal Investigator
  
  浅岡美穂
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  National Institute of Genetics
ショウジョウバエ神経幹細胞プログラムのdecodingPrincipal Investigator
- Principal Investigator
  
  広海健
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  National Institute of Genetics
感覚器特異化に関わる体節内位置情報の遺伝解析
- Principal Investigator
  
  岡部正隆
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  National Institute of Genetics
体節内のボディープランと感覚器特異化の遺伝解析
- Principal Investigator
  
  岡部正隆
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  National Institute of Genetics
感覚器特異化における転写因子ネットワークの遺伝解析
- Principal Investigator
  
  岡部正隆
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  National Institute of Genetics
神経細胞特異化の分子機構Principal Investigator
- Principal Investigator
  
  広海健
- Project Period (FY)
  2000 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  National Institute of Genetics
Cut遺伝子の発現制御に関わる転写因子の同定と感覚器特異化の遺伝解析
- Principal Investigator
  
  岡部正隆
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  National Institute of Genetics
EDLとSPROUTYによるEGF・FGFシグナル伝達経路の制御Principal Investigator
- Principal Investigator
  
  広海健
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  National Institute of Genetics
RAS/MAPKシグナル伝達経路の新しい制御因子・EDLとSPRYPrincipal Investigator
- Principal Investigator
  
  広海健
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  National Institute of Genetics
RAS/MAPKシグナル伝達経路の新しい転写調節機構Principal Investigator
- Principal Investigator
  
  広海健
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  National Institute of Genetics
Nuclear events during neuronal cell fate decisionsPrincipal Investigator
- Principal Investigator
  
  HIROMI Yasushi
- Project Period (FY)
  1997 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (A).
- Research Field
  
  Developmental biology
- Research Institution
  National Institute of Genetics

All 2012 2011 2010 2009 2007 2006 2005 2004

All Journal Article Presentation

[Journal Article] Compartmentalization within neurites : its mechanisms and implications2011
- Author(s)
  Katsuki T., Joshi R., Ailani D., Hiromi Y.
- Journal Title
  
  Dev Neurobiol
  
  Volume: 71 Issue: 6 Pages: 458-473
- DOI
  10.1002/dneu.20859
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21370100
[Journal Article] Midline governs axon pathfinding by coordinating expression of two major guidance systems2009
- Author(s)
  Liu Q. X., Hiramoto M., Ueda H., Gojobori T., Hiromi Y., Hirose S.
- Journal Title
  
  Genes Dev
  
  Volume: 23 Issue: 10 Pages: 1165-70
- DOI
  10.1101/gad.1774209
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21370100
[Journal Article] Intra-axonal patterning : intrinsic compartmentalization of the axonal membrane in Drosophila neurons2009
- Author(s)
  Katsuki T., Ailani D., Hiramoto M., Hiromi Y.
- Journal Title
  
  Neuron
  
  Volume: 64 Issue: 2 Pages: 188-199
- DOI
  10.1016/j.neuron.2009.08.019
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21370100
[Journal Article] Interactions between Plexin-A2, Plexin-A4, and Semaphorin 6A Control Lamina-Restricted Projection of Hippocampal Mossy Fibers.2007
- Author(s)
  Suto, F., Tsuboi, M., Kamiya, H., Mizuno, H., Kiyama, Y., Komai, S., Shimizu, M., Sanbo, M., Yagi, T., Hiromi, Y., Chedotal, A., Mitchell, K.J., Manabe, T., Fujisawa, H.
- Journal Title
  
  Neuron 53
  
  Pages: 535-547
- Data Source
  KAKENHI-PROJECT-18055033
[Journal Article] DRONC coordinates cell death and compensatory proliferation.2006
- Author(s)
  Kondo, S., Senoo-Matsuda, N., Hiromi, Y., Miura, M.
- Journal Title
  
  Mol. Cell. Biol. 26
  
  Pages: 7258-7268
- Data Source
  KAKENHI-PROJECT-18055033
[Journal Article] ROBO directs axon crossing of segmental boundaries by suppressing responsiveness to relocalized Netrin.2006
- Author(s)
  M.Hiramoto, Y.Hiromi
- Journal Title
  
  Nature Neuroscience 9
  
  Pages: 58-66
- Data Source
  KAKENHI-PROJECT-17054043
[Journal Article] seven-up controls switching of transcription factors that specify temporal identities of Drosophila neuroblasts.2005
- Author(s)
  M.I.Kanai, M.Okabe, Y.Hiromi
- Journal Title
  
  Developmental Cell 8
  
  Pages: 203-213
- Data Source
  KAKENHI-PROJECT-17054043
[Journal Article] Cell-type specific utlization of multiple negative feedback loops generates developmental constancy.2005
- Author(s)
  M.Iwanami, Y.Hiromi, M.Okabe
- Journal Title
  
  Genes Cell 10
  
  Pages: 743-752
- Data Source
  KAKENHI-PROJECT-17054043
[Journal Article] Seven-up controls switching of transcription factors that specify temporal identities of Drosophilaneuroblasts2005
- Author(s)
  Kanai, MI., Okabe, M., Hiromi, Y.
- Journal Title
  
  Developmental Cell 8
  
  Pages: 203-213
- Data Source
  KAKENHI-PROJECT-12053265
[Journal Article] A conserved developmental program for sensory organformation in Drosophila melanoqaster2004
- Author(s)
  Niwa, N., Hiromi, Y., Okabe, M.
- Journal Title
  
  Nature Genetics 36
  
  Pages: 293-297
- Data Source
  KAKENHI-PROJECT-12053265
[Journal Article] Coactivator MBF1 preserves the redox-dependent AP-1 activity during oxidative stress in Drosophila2004
- Author(s)
  Jindra, M., Gaziova, I., Uhlirova, M., Okabe, M., Hiromi, Y., Hirose, S.
- Journal Title
  
  EMBO J. 23
  
  Pages: 3538-3547
- Data Source
  KAKENHI-PROJECT-12053265
[Presentation] 極性からパターンへ:神経突起の区画化と神経回路形成2012
- Author(s)
  広海健
- Organizer
  生理学会合同シンポジウム「細胞極性化の原理と生理機能」第117回日本解剖学会総会・全国学術集会
- Place of Presentation
  甲府
- Data Source
  KAKENHI-PROJECT-21370100
[Presentation] Intra-axonal compartmentalization of axon guidance receptors : its mechanism and roles in axon guidance2011
- Author(s)
  Hiromi, Y.
- Organizer
  シンポジウム「Gradients of guidance cues in axon and dendrite patterning」第34回日本神経科学大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21370100
[Presentation] "Intra-axonal compartmentalization" of guidance receptors in drosophila neurons2011
- Author(s)
  Joshi, R., Katsuki, T., DeFalco, T., Hiromi, Y.
- Organizer
  Society for Neuroscience
- Place of Presentation
  Washington, DC
- Data Source
  KAKENHI-PROJECT-21370100
[Presentation] Intra-axonal compartmentalizationof guidance receptors in drosophila neurons2011
- Author(s)
  Joshi, R., Katsuki, T., DeFalco, T., Hiromi, Y.
- Organizer
  Society for Neuroscience
- Place of Presentation
  Washington, DC
- Data Source
  KAKENHI-PROJECT-21370100
[Presentation] "Intra-axonal compartmentalization" of guidance receptors in drosophila neurons2011
- Author(s)
  Joshi, R., Katsuki, T., DeFalco, T., Hiromi, Y.
- Organizer
  Assembly, Plasticity, Dysfunction and Repair of Neural Circuits
- Place of Presentation
  Suzhou
- Data Source
  KAKENHI-PROJECT-21370100
[Presentation] Intra-axonal patterning2011
- Author(s)
  Yasushi Hiromi
- Organizer
  JSDB-GfE Joint Meeting
- Place of Presentation
  Dresden, Germany
- Data Source
  KAKENHI-PROJECT-21370100
[Presentation] Intra-axonal compartments : novel structural units of neural circuits?2011
- Author(s)
  Yasushi Hiromi
- Organizer
  第88回日本生理学会大会第116回日本解剖学会総会・全国学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21370100
[Presentation] Intra-axonal compartmentalizationof guidance receptors in drosophila neurons2011
- Author(s)
  Joshi, R., Katsuki, T., DeFalco, T., Hiromi, Y.
- Organizer
  Assembly, Plasticity, Dysfunction and Repair of Neural Circuits
- Place of Presentation
  Suzhou
- Data Source
  KAKENHI-PROJECT-21370100
[Presentation] Intra-axonal patterning2011
- Author(s)
  Hiromi, Y.
- Organizer
  JSDB-GfE Joint Meeting
- Place of Presentation
  Dresden
- Data Source
  KAKENHI-PROJECT-21370100
[Presentation] Generation of pattern within the axonal membrane2010
- Author(s)
  Hiromi, Y.
- Organizer
  The 13th International Membrane Research Forum
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-21370100
[Presentation] Molecular addresses : motifs involved in compartment-specific localization of guidance receptors in Drosophila axons2009
- Author(s)
  Joshi, R., Katsuki, T., DeFalco, T., Hiromi, Y.
- Organizer
  The 9th Japanese Drosophila Research Conference
- Place of Presentation
  Kakegawa
- Data Source
  KAKENHI-PROJECT-21370100
[Presentation] Differential Trafficking Pathways Regulate the Localization of Axon Guidance Receptors in Drosophila neurons2009
- Author(s)
  Ailani D., Katsuki T., Hiromi Y.
- Organizer
  The 9th Japanese Drosophila Research Conference
- Place of Presentation
  Kakegawa
- Data Source
  KAKENHI-PROJECT-21370100
[Presentation] Intra-axonal patterning : intrinsic compartmentalization of the axonal membrane in Drosophila neurons2009
- Author(s)
  Katsuki, T., Ailani, D., Joshi, R., Defalco, T., Hiramoto, M., Hiromi Y.
- Organizer
  The 9th Japanese Drosophila Research Conference
- Place of Presentation
  Kakegawa
- Data Source
  KAKENHI-PROJECT-21370100

1. OKABE Masataka (10300716)

# of Collaborated Projects: 8 results

# of Collaborated Products: 3 results
2. ASAOKA Miho (40370118)

# of Collaborated Projects: 8 results

# of Collaborated Products: 0 results
3. 小瀬博之 (90314856)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

HIROMI Yasushi 広海 健

Research Projects

Research Products

Co-Researchers

Presentation and suppression of axon guidance molecules by their receptors : a new principle of axon guidancePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

転写因子SEVEN-UPによる遺伝子発現プログラムのスイッチングPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of mechanisms underlying stem cell fate determination in Drosophila germline

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ショウジョウバエ神経幹細胞プログラムのdecodingPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Functional analysis of genes required for germline-stem-cell niche formation in Drosophila ovary

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ショウジョウバエにおける生殖幹細胞ニッチの形成機構とシグナル分子の探索

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ショウジョウバエ神経幹細胞プログラムのdecodingPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

感覚器特異化に関わる体節内位置情報の遺伝解析

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

体節内のボディープランと感覚器特異化の遺伝解析

Principal Investigator

Project Period (FY)

Research Category

Research Institution

感覚器特異化における転写因子ネットワークの遺伝解析

Principal Investigator

Project Period (FY)

Research Category

Research Institution

神経細胞特異化の分子機構Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Cut遺伝子の発現制御に関わる転写因子の同定と感覚器特異化の遺伝解析

Principal Investigator

Project Period (FY)

Research Category

Research Institution

EDLとSPROUTYによるEGF・FGFシグナル伝達経路の制御Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

RAS/MAPKシグナル伝達経路の新しい制御因子・EDLとSPRYPrincipal Investigator

Principal Investigator

HIROMI Yasushi 広海健