TSUKAMOTO Hiroshi 塚本浩

Researcher Number	70304772
Other IDs
Affiliation (based on the past Project Information) *help	2016 – 2017: 九州大学, 医学研究院, 共同研究員 2013 – 2015: 九州大学, 医学(系)研究科(研究院), 准教授 2013: 九州大学, 大学院医学研究院, 准教授 2009 – 2012: Kyushu University, 大学病院, 助教 2007: Kyushu University, University Hospital, Assistant Professor … More 2003 – 2007: KYUSHU UNIVERSITY, University Hospital, Research Associate, 大学病院, 助手 2002: 九州大学, 医学部附属病院, 助手 2000 – 2001: 九州大学, 医学部・附属病院, 助手 Less
Review Section/Research Field	Principal Investigator 膠原病・アレルギー・感染症内科学 / Collagenous pathology/Allergology / 内科学一般 Except Principal Investigator 内科学一般 / 膠原病・アレルギー・感染症内科学
Keywords	Principal Investigator BAFF / APRIL / BR3 / 遺伝子多型 / 関節リウマチ / 自己免疫疾患 / polymorphism / TNF family / 疾患感受性遺伝子 / B細胞 … More / サイトカイン / TNFファミリー / 全身性エリテマトーデス / 共刺激分子 / グランザイム / 細胞障害活性 / IL-13 / CD8陽性T細胞 / 細胞傷害活性 / 全身性強皮症 / CD226 / rheumatoid arthritis / svnovial fibroblast-like cells / autoimmune disease / 共刺激 / Furin転換酵素 / 滑膜細胞 / susceptible gene / SLE / B cell / cytokine / single nucleotide polymorphisims / genetic analysis / Rheumatoid arthritis / Systemic lupus erythematosus / 慢性関節リウマチ / 一塩基多型(SNP) / 一塩基多型 / 遺伝子解析 / TACE / TNF変換酵素 / TNF / 細胞内ドメイン / SPPL / TNF-α変換酵素 / TNF-α / 膜内蛋白分解酵素 / 間葉系幹細胞 / 制御性T細胞 / 強皮症 / 遺伝子発現プロファイル / 移植 / 造血幹細胞 / 純化 / 免疫再構築 / CD34陽性細胞 / 造血幹細胞移植 … More Except Principal Investigator サイトカイン / TNF / アポトーシス / 関節リウマチ / 抗TNF療法 / TNF-α / cell-cycle arrest / apoptosis / rheumatoid arthritis / anti-TNF therapy / Cytokine / シグナル伝達 / 細胞周期 / Rheumatoid arthritis / Crohn's disease / anti-TNF-αtherapy / cytokine / クローン病 / CD4+ T cell / E-selectm / 細胞内シグナル伝達 / 炎症 / 輸送 Less

Investigation of the role of CD226+CD8+T cells in the pathogenesis of systemic sclerosis and an application to therapyPrincipal Investigator
- Principal Investigator
  
  Tsukamoto Hiroshi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Collagenous pathology/Allergology
- Research Institution
  Kyushu University
Identification of the new function of TNF induced by intramembrane proteases and the application to regulate inflammatory diseases.Principal Investigator
- Principal Investigator
  
  TSUKAMOTO Hiroshi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  Kyushu University
Clarification of the mechanisms of intracellular trafficking of TNF
- Principal Investigator
  
  HORIUCHI Takahiko
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  Kyushu University
Development of a new stem cell transplantation regimen in the treatment of refractory autoimmune diseasesPrincipal Investigator
- Principal Investigator
  
  TSUKAMOTO Hiroshi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  Kyushu University
Functional analysis of BAFF, APRIL and their receptors, and the study of their role in the pathogenesis of autoimmune diseasePrincipal Investigator
- Principal Investigator
  
  TSUKAMOTO Hiroshi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  Kyushu University
Functional analyses for transmembrane TNF-alpha
- Principal Investigator
  
  HORIUCHI Takahiko
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  KYUSHU UNIVERCITY
Functional analysis of APRIL and BAFF, and the study of their role in the pathogenesis of autoimmune diseasePrincipal Investigator
- Principal Investigator
  
  TSUKAMOTO Hiroshi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  KYUSHU UNIVERSITY
The association of the gene polymorphism of APRIL and BAFF with autoimmune diseases : Functional analysisPrincipal Investigator
- Principal Investigator
  
  TSUKAINOTO Hiroshi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  KYUSHU UNIVERSITY
Analysis of the function of membrane TNF-α
- Principal Investigator
  
  HORIUCHI Takahiko
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  Kyushu University
Functional analysis of membrane TNF-α
- Principal Investigator
  
  HORIUCHI Takahiko
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  KYUSHU UNIVERSITY

[Book] 見逃すと怖い膠原病100の質問2014
- Author(s)
  塚本　浩
- Total Pages
  230
- Publisher
  メディカルビュー社
- Data Source
  KAKENHI-PROJECT-24591465
[Book] 免疫・アレルギー疾患イラストレイテッド2013
- Author(s)
  田中良哉、渥美達也、塚本浩、他
- Total Pages
  358
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-24591465
[Book] 補体への招待2011
- Author(s)
  大井洋之、木下タロウ、松下操、塚本浩堀内孝彦、他
- Total Pages
  232
- Publisher
  メジカルレビュー社
- Data Source
  KAKENHI-PROJECT-21591266
[Book] 補体への招待2011
- Author(s)
  大井洋之, 木下タロウ, 松下操, 塚本浩, 他
- Total Pages
  232
- Publisher
  メジカルレビュー社
- Data Source
  KAKENHI-PROJECT-21591266
[Journal Article] Beneficial use of serum ferritin and heme oxygenase-1 as biomarkers in adult-onset Still's disease: A multicenter retrospective study.2018
- Author(s)
  Kirino Y, Kawaguchi Y, Tada Y, Tsukamoto H, Ota T, Iwamoto M, Takahashi H, Nagasawa K, Takei S, Horiuchi T, Ichida H, Minota S, Ueda A, Ohta A, Ishigatsubo Y.
- Journal Title
  
  Mod Rheumatol
  
  Volume: 印刷中 Issue: 5 Pages: 1-7
- DOI
  10.1080/14397595.2017.1422231
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09527, KAKENHI-PROJECT-15K15374, KAKENHI-PROJECT-26713036
[Journal Article] Shared epitope positivity is related to efficacy of abatacept in rheumatoid arthritis.2018
- Author(s)
  Oryoji K, Yoshida K, Kashiwado Y, Tanaka K, Mizuki SI, Tsukamoto H, Kamada K, Akashi K.
- Journal Title
  
  Ann Rheum Dis
  
  Volume: 印刷中 Issue: 8 Pages: 1234-1236
- DOI
  10.1136/annrheumdis-2017-211430
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09527
[Journal Article] A novel scoring system based on common laboratory tests predicts the efficacy of TNF-inhibitor and IL-6 targeted therapy in patients with rheumatoid arthritis: a retrospective, multicenter observational study.2017
- Author(s)
  Nakagawa J, Koyama Y, Kawakami A, Ueki Y, Tsukamoto H, Horiuchi T, Nagano S, Uchino A, Ota T, Akahoshi M, Akashi K.
- Journal Title
  
  Arthritis Res Ther
  
  Volume: 19 Issue: 1
- DOI
  10.1186/s13075-017-1387-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09527
[Journal Article] Functional interleukin-33 receptors are expressed in early progenitor stages of allergy-related granulocytes.2017
- Author(s)
  Tsuzuki H, Arinobu Y, Miyawaki K, Takaki A, Ota SI, Ota Y, Mitoma H, Akahoshi M, Mori Y, Iwasaki H, Niiro H, Tsukamoto H, and Akashi K.
- Journal Title
  
  Immunology
  
  Volume: 150 Issue: 1 Pages: 64-73
- DOI
  10.1111/imm.12667
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09527, KAKENHI-PROJECT-15K15365, KAKENHI-PROJECT-15K09528
[Journal Article] Smoking history, alcohol consumption, sports activity and the risk of developing systemic lupus erythematosus in a Japanese population.2017
- Author(s)
  Nakano TW, M., Kiyohara, C,; Tsukamoto,H.; Sawabe, T.; Nishizaka, H.; Horiuchi, T .
- Journal Title
  
  Int Med J
  
  Volume: 24 Pages: 366-70
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09527
[Journal Article] Clinical and Genetic Features of Patients With TNFRSF1A Variants in Japan: Findings of a Nationwide Survey2016
- Author(s)
  Ueda, N. Ida, H. Washio, M. Miyahara, H. Tokunaga, S. Tanaka, F. Takahashi, H. Kusuhara, K. Ohmura, K. Nakayama, M. Ohara, O. Nishikomori, R. Minota, S. Takei, S. Fujii, T. Ishigatsubo, Y. Tsukamoto, H. Tahira, T. Horiuchi, T.
- Journal Title
  
  Arthritis Rheumatol
  
  Volume: 68 Issue: 11 Pages: 2760-2771
- DOI
  10.1002/art.39793
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04876, KAKENHI-PROJECT-15K09527, KAKENHI-PROJECT-16K09913
[Journal Article] Generation mechanism of RANKL(+) effector memory B cells: relevance to the pathogenesis of rheumatoid arthritis.2016
- Author(s)
  Ota Y, Niiro H, Ota S, Ueki N, Tsuzuki H, Nakayama T, Mishima K, Higashioka K, Jabbarzadeh-Tabrizi S, Mitoma H, Akahoshi M, Arinobu Y, Kukita A, Yamada H, Tsukamoto H, and Akashi K.
- Journal Title
  
  Arthritis Res Ther
  
  Volume: 18 Issue: 1 Pages: 67-67
- DOI
  10.1186/s13075-016-0957-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09527, KAKENHI-PROJECT-15K09528, KAKENHI-PROJECT-16K10908
[Journal Article] Quality of life in Japanese female patients with systemic lupus erythematosus: Evaluation using the Short Form 36 Health Survey.2016
- Author(s)
  Furukawa M, Kiyohara C, Horiuchi T, Tsukamoto H, Mitoma H, Kimoto Y, Uchino A, Nakagawa M, Oryoji K, Shimoda T, and Akashi K.
- Journal Title
  
  Mod Rheumatol
  
  Volume: 26 Issue: 2 Pages: 240-247
- DOI
  10.3109/14397595.2015.1060668
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09527
[Journal Article] Longterm Safety and Efficacy of Subcutaneous Tocilizumab Monotherapy: Results from the 2-year Open-label Extension of the MUSASHI Study.2015
- Author(s)
  Ogata A, Amano K, Dobashi H, Inoo M, Ishii T, Kasama T, Kawai S, Kawakami A, Koike T, Miyahara H, Miyamoto T, Munakata Y, Murasawa A, Nishimoto N, Ogawa N, Ojima T, Sano H, Shi K, Shono E, Suematsu E, Takahashi H, Tanaka Y, Tsukamoto H, Nomura A and Investigators MS.
- Journal Title
  
  The Journal of rheumatology
  
  Volume: 42 Issue: 5 Pages: 799-809
- DOI
  10.3899/jrheum.140665
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591465, KAKENHI-PROJECT-26461477
[Journal Article] Serum progranulin levels are elevated in dermatomyositis patients with acute interstitial lung disease, predicting prognosis.2015
- Author(s)
  Tanaka A, Tsukamoto H, Mitoma H, Kiyohara C, Ueda N, Ayano M, Ohta S, Kimoto Y, Akahoshi M, Arinobu Y, Niiro H, Tada Y, Horiuchi T and Akashi K.
- Journal Title
  
  Arthritis research & therapy
  
  Volume: 17 Issue: 1 Pages: 27-27
- DOI
  10.1186/s13075-015-0547-z
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24591465, KAKENHI-PROJECT-15K09527, KAKENHI-PROJECT-15K09528
[Journal Article] Increased CD226 Expression on CD8+ T Cells Is Associated with Upregulated Cytokine Production and Endothelial Cell Injury in Patients with Systemic Sclerosis.2015
- Author(s)
  Ayano M, Tsukamoto H, Kohno K, et al.
- Journal Title
  
  J Immunol
  
  Volume: 195 Issue: 3 Pages: 892-900
- DOI
  10.4049/jimmunol.1403046
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K09527, KAKENHI-PROJECT-15K09528, KAKENHI-PROJECT-15K15365, KAKENHI-ORGANIZER-22130001, KAKENHI-PROJECT-25253069
[Journal Article] Reduced carotid intima-media thickness in systemic lupus erythematosus patients treated with cyclosporine A2014
- Author(s)
  Oryoji K, Kiyohara C, Horiuchi T, Tsukamoto H, Niiro H, Shimoda T, Akashi K, Yanase T
- Journal Title
  
  Mod Rheumatol
  
  Volume: 24 Pages: 86-92
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591464
[Journal Article] Evaluation of the extent of ground-glass opacity on high-resolution CT in patients with interstitial pneumonia associated with systemic sclerosis: Comparison between quantitative and qualitative analysis.2014
- Author(s)
  Yabuuchi H, Matsuo Y, Tsukamoto H, Horiuchi T, Sunami S, Kamitani T, Jinnouchi M, Nagao M, Akashi K and Honda H.
- Journal Title
  
  Clinical radiology
  
  Volume: 69 Issue: 7 Pages: 758-64
- DOI
  10.1016/j.crad.2014.03.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591465
[Journal Article] Prevalence and risk factors of vertebral fracture in Japanese females with systemic lupus erythematosus2013
- Author(s)
  Furukawa M, Kiyohara C, Horiuchi T, Tsukamoto H, Mitoma H, Kimoto Y, Uchino A, Nakagawa M, Oryoji K, Shimoda T, Harada M, Akashi K
- Journal Title
  
  Mod. Rheumatol
  
  Volume: 23 Issue: 4 Pages: 765-773
- DOI
  10.1007/s10165-012-0735-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591464, KAKENHI-PROJECT-24591465
[Journal Article] Prevalence and risk factors of vertebral fracture in Japanese females with systemic lupus erythematosus2013
- Author(s)
  Furukawa M, Kiyohara C, Horiuchi T, Tsukamoto H, Mitoma H, Kimoto Y, Uchino A, Nakagawa M, Oryoji K, Shimoda T, Harada M, Akashi K
- Journal Title
  
  Mod. Rheumatol
  
  Volume: 23(4) Pages: 765-773
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591464
[Journal Article] Tumor necrosis factor receptor-associated periodic syndrome (TRAPS) in Japan: a review of the literature.2013
- Author(s)
  Washio M, Nakano T, Kawaguchi Y, Takagi K, Kiyohara C, Tsukamoto H, Tokunaga S, Horiuchi T.
- Journal Title
  
  Mod Rheumatol
  
  Volume: 23 Pages: 210-7
- DOI
  10.1007/s10165-012-0737-3
- NAID
  10031167691
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591465
[Journal Article] The cytotoxic effects of certolizumab pegol and golimumab mediated by transmembrane tumor necrosis factor α.2013
- Author(s)
  Ueda N, Tsukamoto H, Mitoma H, Ayano M, Tanaka A, Ohta S, Inoue Y, Arinobu Y, Niiro H, Akashi K, Horiuchi T.
- Journal Title
  
  Inflamm Bowel Dis.
  
  Volume: 19 Issue: 6 Pages: 1224-1231
- DOI
  10.1097/mib.0b013e318280b169
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591463, KAKENHI-PROJECT-23591464, KAKENHI-PROJECT-24591450, KAKENHI-PROJECT-24591465
[Journal Article] Association of hepatitis B with antirheumatic drugs: a case-control study.2013
- Author(s)
  Oshima Y, Tojo A, et al.
- Journal Title
  
  Mod Rheumatol.
  
  Volume: 23 Issue: 4 Pages: 694-704
- DOI
  10.1007/s10165-012-0709-7
- NAID
  10031189163
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591373, KAKENHI-PROJECT-24591465
[Journal Article] The cytotoxic effects of certolizumab pegol and golimumab mediated by transmembrane tumor necrosis factorα2013
- Author(s)
  Ueda N, Tsukamoto H, Mitoma H, Ayano M, Tanaka A, Ohta S-I, Inoue Y, Arinobu Y, Niiro H, Akashi K, Horiuchi T
- Journal Title
  
  Inflamm. Bowel Dis
  
  Volume: 19(6) Pages: 1224-1231
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591464
[Journal Article] Reduced carotid intima-media thickness in systemic lupus erythematosus patients treated with cyclosporine A.2013
- Author(s)
  Oryoji K, Kiyohara C, Horiuchi T, Tsukamoto H, Niiro H, Shimoda T, Akashi K, Yanase T
- Journal Title
  
  Mod Rheumatol
  
  Volume: 24 Issue: 1 Pages: 86-92
- DOI
  10.3109/14397595.2013.852838
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591450, KAKENHI-PROJECT-24591465
[Journal Article] Serum progranulin levels are elevated in patients with systemic lupus erythematosus,reflecting disease activity2012
- Author(s)
  Tanaka A, Tsukamoto H, Mitoma H, Kiyohara C, Ueda N, Ayano M, Ohta SI, Inoue Y, Arinobu Y, Niiro H, Horiuchi T, Akashi K
- Journal Title
  
  Arthritis Res. Ther
  
  Volume: (Epub ahead of print)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591464
[Journal Article] CIN85 is required for Cbl-mediated regulation of antigen receptor signaling in human B cells2012
- Author(s)
  Niiro H,…, Tsukamoto H, et al(16名中12番目)
- Journal Title
  
  Blood
  
  Volume: 119 Issue: 10 Pages: 2263-2273
- DOI
  10.1182/blood-2011-04-351965
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591266, KAKENHI-PROJECT-24590944, KAKENHI-PROJECT-24591450, KAKENHI-PROJECT-24591465
[Journal Article] Guideline for Hereditary Angioedema (HAE) 2010 by the Japanese Association for Complement Research2012
- Author(s)
  Horiuchi T, Ohi H, Ohsawa I, Fujita T, Matsushita M, Okada N, Seya T, Yamamoto T, Endo Y, Hatanaka M, Wakamiya N, Mizuno M, Nakao M, Okada H, Tsukamoto H, Matsumoto M, Inoue N, Nonaka M, Kinoshita T
- Journal Title
  
  Allergol. Int
  
  Volume: 61(4) Pages: 559-562
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591464
[Journal Article] CIN85 is required for Cbl-mediated regulation of antigen receptor signaling in human B cells2012
- Author(s)
  Niiro H, Jabbarzadeh-Tabrizi S, Kikushige Y, Shima T, Noda K, Ota S-I, Tsuzuki H, Inoue Y, Arinobu Y, Iwasaki H, Shimoda S, Baba E, Tsukamoto H, Horiuchi T, Taniyama T, Akashi K
- Journal Title
  
  Blood
  
  Volume: 119(10) Pages: 2263-2273
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591464
[Journal Article] CIN8s is required for Cbl-mediated regulation of antigen receptor signaling in human B cells2012
- Author(s)
  Niiro H, JabbarzadehTabrizi S, Kikushige Y, Shima T, Neda K, eta S, Tsuzuki H, Inoue Y, Arinobu Y, Iwasaki H, Shimoda S, Baba E, Tsukamoto H, Horiuchi T, Taniyama T, and Akashi K.
- Journal Title
  
  Blood
  
  Volume: 119 Pages: 2263-2273
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591266
[Journal Article] Serum progranulin levels are elevated in patients with systemic lupus erythematosus, reflecting disease activity.2012
- Author(s)
  Tanaka A, Tsukamoto H, Mitoma H, Kiyohara C, Ueda N, Ayano M, Ohta SI, Inoue Y, Arinobu Y, Niiro H, Horiuchi T, Akashi K.
- Journal Title
  
  Arthritis Res Ther.
  
  Volume: 14 Issue: 6
- DOI
  10.1186/ar4087
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591463, KAKENHI-PROJECT-24591465
[Journal Article] Hereditary angioedema in Japan : Genetic analysis of 13 unrelated cases2012
- Author(s)
  Yam amoto T, Horiuchi T, Miyahara H, Yoshizawa S, Maehara J, Shono E, Takamura K, Machida H, Tsujioka K, Kaneko T, Uemura N, Suzawa K, Inagaki N, Umegaki N, Kasamatsu Y, Hara A, Arinobu Y, Inoue Y, Niiro H, Kashiwagi Y, Harashima SI, Tahira T, Tsukamoto H, Akashi K
- Journal Title
  
  Am. J. Med. Sci
  
  Volume: 343(3) Pages: 210-214
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591464
[Journal Article] Hereditary Angioedema in Japan: Genetic Analysis of 13 Unrelated Cases2012
- Author(s)
  Yamamoto, T. Horiuchi, T. Miyahara, H. Yoshizawa, S. Inagaki, N. Umegaki, N. Kasamatsu, Y. Hara, A. Arinobu, Y. Inoue, Y. Niiro, H. Tsukamoto, H. Akashi, K.
- Journal Title
  
  Am J Med Sci
  
  Volume: 343 Issue: 3 Pages: 210-214
- DOI
  10.1097/maj.0b013e31822bdb65
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591465
[Journal Article] Hereditary Angioedema in Japan : Genetic Analysis of 13 Unrelated Cases2011
- Author(s)
  Yamamoto T, Horiuchi T, Miyahara H, Yoshizawa S, Maehara J, Shono E, Takamura K, Machida H, Tsujioka K, Kaneko T, Uemura N, Suzawa K, Inagaki N, Umegaki N, Kasamatsu Y, Hara A, Arinobu Y, Inoue Y, Niiro H, Kashiwagai Y, Harashima SI, Tahira T, Tsukamoto H
- Journal Title
  
  Am J Med Sci
  
  Volume: 342 Pages: 210-214
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591266
[Journal Article] Prevalence of and risk factors for low bone mineral density in Japanese female patients with systemic lupus erythematosus2011
- Author(s)
  Furukawa M, Kiyohara C, Tsukamoto H, Mitoma H, Kimoto Y, Uchino A, Nakagawa M, Oryoji K, Shimoda T, Akashi K, Harada M, Horiuchi T.
- Journal Title
  
  Rheumatol Int
  
  Volume: 31 Pages: 365-76
- NAID
  120004951587
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591266
[Journal Article] Analysis of immune re constitution after autologous CD34+ stem/progenitor cell transplantation for systemic sclerosis2011
- Author(s)
  Tsukamoto H, Nagafuji K, Horiuchi T, Mitoma H, Niiro H, Arinobu Y, Inoue Y, To K, Miyamoto T, Iwasaki H, Teshima T, Harada M, Akashi K.
- Journal Title
  
  predominant reconstitution of Th1 CD4+ T cells. Rheumatology
  
  Volume: 50 Pages: 944-52
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591266
[Journal Article] Immune reconstitution after PBSCT for SSc2011
- Author(s)
  Tsukamoto H, Nagafuji K, Horiuchi T, et al.
- Journal Title
  
  Rheumatology
  
  Volume: 50 Pages: 944-952
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591464
[Journal Article] Correlation between pretreatment or follow-up CT findings and therapeutic effect of autologous peripheral blood stem cell transplantation for interstitial pneumonia associated with systemic sclerosis2011
- Author(s)
  Yabuuchi H, Matsuo Y, Tsukamoto H, Sunami S, Kamitani T, Sakai S, Hatakenaka M, Nagafuji K, Horiuchi T, Harada M, Akashi K, Honda H
- Journal Title
  
  Eur. J. Radiol
  
  Volume: 79(2)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591464
[Journal Article] Analysis of immune reconstitution after autologous CD34+ stem/progenitor cell transplantation for systemic sclerosis : predominant reconstitution of Th1 CD4+ T cells2011
- Author(s)
  Tsukamoto H, Nagafuji K, Horiuchi T, et al
- Journal Title
  
  Rheumatology
  
  Volume: 50 Pages: 944-952
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591266
[Journal Article] Correlation between pretreatment or follow-up CT findings and therapeutic effect of autologous peripheral blood stem cell transplantation for interstitial pneumonia associated with systemic sclerosis2011
- Author(s)
  Yabuuchi H, Matsuo Y, Tsukamoto H, Sunami S, Kamitani T, Sakai S, Hatakenaka M, Nagafuji K, Horiuchi T, Harada M, Akashi K, Honda H.
- Journal Title
  
  Eur J Radiol
  
  Volume: 79
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591266
[Journal Article] Correlation between pretreatment or follow-up CT findings and therapeutic effect of autologous peripheral blood stem cell transplantation for interstitial pneumonia associated with systemic sclerosis2011
- Author(s)
  Yabuuchi H, Matsuo Y, Tsukamoto H, et al
- Journal Title
  
  Eur J Radiol
  
  Volume: 79 Issue: 2 Pages: e74-e79
- DOI
  10.1016/j.ejrad.2011.03.078
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591266
[Journal Article] Analysis of immune reconstitution after autologous CD34+ stem/progenitor cell transplantation for systemic sclerosis : predominant reconstitution of Th1 CD4+ T cells2011
- Author(s)
  Tsukamoto H, Nagafuji K, Horiuchi T, Mitoma H, Niiro H, Arinobu Y, Inoue Y, To K, Miyamoto T, Iwasaki H, Teshima T, Harada M, Akashi K
- Journal Title
  
  Rheumatology (Oxford)
  
  Volume: 50(5) Pages: 944-952
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591464
[Journal Article] Prevalence of and risk factors for low bone mineral density in Japanese female patients with systemic lupus erythematosus2011
- Author(s)
  Furukawa M, Kiyohara C, Tsukamoto H, Mitoma H, Kimoto Y, Uchino A, Nakagawa M, Oryoji K, Nakashima H, Akashi K, Harada M, Horiuchi T
- Journal Title
  
  Rheumatol. Int
  
  Volume: 31(3) Pages: 365-376
- NAID
  120004951587
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591464
[Journal Article] Association of killer cell immunoglobulin-like receptoi 2DL5 with systemic lupus erythematosus and accompanying infections2010
- Author(s)
  Kimoto Y, Horiuchi T, Tsukamoto H, Kiyohara C, Mitoma H, Uchino A, Furugo I, Yoshizawa S, Ueda A, Harashima S, Sawabe T, Tahira T, Hayashi K, Yoshizawa S, Shimoda T, Akashi K, Harada M.
- Journal Title
  
  Rheumatology
  
  Volume: 49 Pages: 1346-1353
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591266
[Journal Article] Tacrolimus is effective for lupus nephritis patients with persistent proteinuria.2010
- Author(s)
  Uchino A, Tsukamoto H, Nakashima H, et al.
- Journal Title
  
  Clin Exp Rheumatol
  
  Volume: 28 Pages: 6-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591266
[Journal Article] Association of killer cell immunoglobulin-like receptor 2DL5 with systemic lupus erythematosus and accompanying infections.2010
- Author(s)
  Kimoto Y, Horiuchi T, Tsukamoto H, et al.
- Journal Title
  
  Rheumatology
  
  Volume: 49 Pages: 1346-53
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591266
[Journal Article] Tacrolimus is effective for lupus nephritis patients with persistent proteinuria2010
- Author(s)
  Uchino A, Tsukamoto H, Nakashima H, Yoshizawa S, Furugo I, Mitoma H, Oryoji K, Shimoda T, Niiro H, Tada Y, Yano T, Nonaka T, Oishi R, Akashi K, Horiuchi T.
- Journal Title
  
  Clin Exp Rheumatol
  
  Volume: 28 Pages: 6-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591266
[Journal Article] Infectious complications in patients receiving autologous CD34selected hematopoietic stem cell transplantation for severe autoimmune diseases2009
- Author(s)
  Kohno K, Nagafuji K, Tsukamoto H, Horiuchi T, Takase K, Aoki K, Henzan H, Kamezaki K, Takenaka K, Miyamoto T, Teshima T, Harada M, Akashi K.
- Journal Title
  
  Transpl Infect Dis
  
  Volume: 11 Pages: 318-323
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591266
[Journal Article] Infectious complications in patients receiving autologous CD34-selectedhematopoitic stem cell transplantation for severe autoimmune diseases2009
- Author(s)
  Kohno K, Nagafuji K, Tsukamoto H, et al.
- Journal Title
  
  Transpl infect dis 11
  
  Pages: 318-323
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591266
[Journal Article] Kyushu Sapporo SLE Study Group. Combination of TNF-RII, CYP1A1 and GSTM1 polymorphisms and the risk of Japanese SLE : findings from the KYSS study2009
- Author(s)
  Horiuchi T, Washio M, Kiyohara C, Tsukamoto H, Tada Y, Asami T, Ide S, Kobashi G, Takahashi H
- Journal Title
  
  Rheumatology
  
  Volume: 48 Pages: 1045-1049
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591266
[Journal Article] Mechanism for cytotoxic effects of anti-TNF-a agents on transmembrane TNF-expressing cells:comparison among infliximab,etanercept and adalibmab2008
- Author(s)
  Mitoma H, Horiuchi T, Tsukamoto H, et. al.
- Journal Title
  
  Arthritis Rheum (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591113
[Journal Article] Mechanisms for cytotoxic effects of anti-tumor necrosis factor agents on transmembrane tumor necrosis factor alpha-expressing cells: Comparison among infliximab,etanercept,and adalimumab2008
- Author(s)
  Mitoma H, Horiuchi T, Tsukamoto H, et. al.
- Journal Title
  
  Arthritis Rheum 58
  
  Pages: 1248-57
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591113
[Journal Article] Association of polymorphisms in complement component C3 gene with susceptibility to systemic lupus erythematosus2008
- Author(s)
  Miyagawa, H, Yamai, M, Kiyohara, C, Tsukamoto, H, Kimoto, Y, Nakamura, T, Lee, J-H., Tsai, C-Y., Tsai, C-Y, Chiang, B-L, Shimoda, T, Harada, M, Tahira, T, Hayashi, K, Horiuchi, T
- Journal Title
  
  Rheumatology 47
  
  Pages: 158-64
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591113
[Journal Article] Mechanism for cytotoxic effects of anti-TNF-α agents on transmembrane TNF-expressing cells : comparison among infliximab, etanercept and adalibmab2008
- Author(s)
  Mitoma, H, Horiuchi, T, Tsukamoto, H, Tamimoto, Y, Kimoto, Y, Uchino, A, To, K, Harashima, S, Hatta, N, Harada, M
- Journal Title
  
  Arthritis Rheum 58
  
  Pages: 1248-57
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591113
[Journal Article] A dose-escalation study of rituximab for treatment of systemic lupus erythematosus and Evans' syndrome : Immunological analysis of B cells, T cells and cytokines2008
- Author(s)
  Tamimoto, Y, Horiuchi, T, Tsukamoto, H, Kiyohara, C, Niro, H, Miyagawa, H, Nakasone, A, Mitoma, H, Kimoto, Y, Uchino, A, Muta, K, Abe, Y, Inoue, Y, Ueda, A, Nakashima, H, Tada, Y, Nagasawa, K, Yoshizawa, S, Shimoda, T, Harada, M
- Journal Title
  
  Rheumatology (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591113
[Journal Article] A functional M196R polymorphism of TNF receptor type 2 is associated with SLE : a case control study and a meta-analysis2007
- Author(s)
  Horiuchi T, Kiyohara C, Tsukamoto H et al.
- Journal Title
  
  Ann Rheum Dis 66(3)
  
  Pages: 320-324
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591048
[Journal Article] A functional M196R polymorphism of tumor necrosis factor receptor type 2 is associated with systemic lupus erythematosus : A case-control study and a meta-analysis.2007
- Author(s)
  Horiuchi T, Kiyohara C, Tsukamoto H, et al.
- Journal Title
  
  Ann Rheum Dis 66
  
  Pages: 320-324
- Data Source
  KAKENHI-PROJECT-18591113
[Journal Article] A functional M196R polymorphism of tumor necrosis factor receptor type 2 is associated with systemic lupus erythematosus : A case-control study and a meta-analysis2007
- Author(s)
  Horiuchi, T, Kiyohara, C, Tsukamoto, H, Sawabe, T, Furugo, I, Yoshizawa, S, Ueda, A, Nakamura, Y, Tada, Y, Kimoto, Y, Mitoma, H, Harashima, SI, Yoshizawa, S, Shimoda, T, Okamura, S, Nagasawa, K, Harada, M
- Journal Title
  
  Ann Rheum Dis 66
  
  Pages: 320-324
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591113
[Journal Article] A functional M196R polymorphism of tumor necrosis factor receptortype 2 is associated with systemic lupus erythematosus:A case-control study and a meta-analysis2007
- Author(s)
  Horiuchi T, Kiyohara C, Tsukamoto H, et. al.
- Journal Title
  
  Ann Rheum Dis 66
  
  Pages: 320-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591113
[Journal Article] A functional M196R polymorphism of tumor necrosis factor receptor type 2 is associated with systemic lupus erythematosus: A case-control study and a meta-analysis2007
- Author(s)
  Horiuchi T, Kiyohara C, Tsukamoto H, et. al.
- Journal Title
  
  Ann Rheum Dis 66
  
  Pages: 320-4
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591113
[Journal Article] Increased expression of membrane TNF-alpha on activated peripheral CD8+ T cells in systemic lupus erythematosus.2006
- Author(s)
  Horiuchi T, Morita C, Tsukamoto H et al.
- Journal Title
  
  Int J Mol Med 17
  
  Pages: 875-879
- Data Source
  KAKENHI-PROJECT-18591113
[Journal Article] A Phase I-II Trial of autologous peripheral blood stem cell transplantation in the treatment of refractory autoimmune disease2006
- Author(s)
  Tsukamoto H, Nagafuji K, Horiuchi T, et al.
- Journal Title
  
  Ann Rheum Dis 65(4)
  
  Pages: 508-514
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591048
[Journal Article] A Phase I-II trial of autologous peripheral blood stem cell transplantation in the treatment of refractory autoimmune disease.2006
- Author(s)
  Tsukamoto H, Nagafuji K, Horiuchi T, Miyamoto T, Aoki K, Takase K, Henzan H, Himeji D, Koyama T, Miyake K, Inoue Y, Nakashima H, Otsuka T, Tanaka Y, Nagasawa K, Harada M
- Journal Title
  
  Ann Rheum Dis 65
  
  Pages: 508-514
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590984
[Journal Article] Increased expression of membrane TNF-alpha on activated peripheral CD8+ T cells in systemic lupus erythematosus2006
- Author(s)
  Horiuchi, T, Morita, C, Tsukamoto, H, Mitoma, H, Sawabe, T, Harashima, S, Kashiwagi, Y, Okamura, S
- Journal Title
  
  Int J Mol Med 17
  
  Pages: 875-9
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591113
[Journal Article] A Phase I-II trial of autologous peripheral blood stem cell transplantation in the treatment of refractory autoimmune disease2006
- Author(s)
  Tsukamoto, H, Nagafuji, K, Horiuchi, T, Miyamoto, T, Aoki, K, Takase, K, Henzan, H, Himeji, D, Koyama, T, Miyake, K, Inoue, Y, Nakashima, H, Otsuka, T, Tanaka, Y, Nagasawa, K, Harada, M
- Journal Title
  
  Ann Rheum Dis 65
  
  Pages: 508-14
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591113
[Journal Article] A phaseI-II trial of autologous peripheral blood stem cell transplantation in the treatment of refractory autoimmune disease2006
- Author(s)
  Tsukamoto H, Nagafuji K, Horiuchi T, et. al.
- Journal Title
  
  Ann Rheum Dis 65
  
  Pages: 508-14
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591113
[Journal Article] Increased expression of membrane TNF-alpha on activated peripheral CD8+ T cells in systemic lupus erythematosus2006
- Author(s)
  Horiuchi T, Morita C, Tsukamoto H et al.
- Journal Title
  
  Int J Mol Med 17(5)
  
  Pages: 875-879
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591048
[Journal Article] A phase I-II trial of autologous peripheral blood stem cell transplantation in the treatment of refractory autoimmune disease.2006
- Author(s)
  Tsukamoto H, Nagafuji K, Horiuchi T, et al.
- Journal Title
  
  Ann Rheum Dis 65
  
  Pages: 508-514
- Data Source
  KAKENHI-PROJECT-18591113
[Journal Article] A Phase I-II Trial of autologous peripheral blood stem cell transplantation in the treatment of refractory autoimmune disease2006
- Author(s)
  Tsukamoto H, Nagafuji K, Horiuchi T, et al.
- Journal Title
  
  Ann Rheum Dis 65 (4)
  
  Pages: 508-514
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591048
[Journal Article] A Phase I-II trial of autologous peripheral blood stem cell transplantation in the treatment of refractory autoimmune disease2006
- Author(s)
  Tsukamoto H, Nagafuji K, Horiuchi T et al.
- Journal Title
  
  Ann Rheum Dis 65
  
  Pages: 508-514
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590984
[Journal Article] Decreased expression of interleukin-21 receptor on peripheral B lymphocytes in systemic lupus erythematosus.2005
- Author(s)
  Mitoma H, Horiuchi T, Kimoto Y, Tsukamoto H, Uchino A, Tamimoto Y, Miyagi Y, Harada M
- Journal Title
  
  Int J Mol Med 16
  
  Pages: 609-615
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590984
[Journal Article] Infliximab induces potent anti-inflammatory responses by outside-to-inside signals through transmembrane TNF-alpha.2005
- Author(s)
  Mitoma H, Horiuchi T, Hatta N, Tsukamoto H, Harashima S, Kikuchi Y, Otsuka J, Okamura S, Fujita S, Harada M
- Journal Title
  
  Gastroenterology 128
  
  Pages: 376-392
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590984
[Journal Article] Decreased expression of interleukin-21 receptor on peripheral B lymphocytes in systemic lupus erythematosus2005
- Author(s)
  Mitoma H, Horiuchi T, Kimoto Y, Tsukamoto H et al.
- Journal Title
  
  Int J Mol Med 16
  
  Pages: 609-615
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590984
[Journal Article] Molecular analysis of a novel hereditary C3 deficienc with systemic lupus erythematosus2005
- Author(s)
  Tsukamoto H, Horiuchi T et al.
- Journal Title
  
  Biochem Biophys Res Commun 330
  
  Pages: 298-304
- Data Source
  KAKENHI-PROJECT-17591048
[Journal Article] Association of MBL gene polymorphisms with major bacterial infection in patients treated with high-dose chemotherapy and autologous PBSCT.2005
- Author(s)
  Horiuchi T, Gondo H, Miyagawa H, Otsuka J, Inaba S, Nagafuji K, Takase K, Tsukamoto H, Koyama T, Mitoma H, Tamimoto Y, Miyagi Y, Tahira T, Hayashi K, Hashimura C, Okamura S, Harada M
- Journal Title
  
  Genes Immun 6
  
  Pages: 162-166
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590984
[Journal Article] Raised serum APRIL levels in patients with systemic lupus erythematosus.2005
- Author(s)
  Koyama T, Tsukamoto H, Miyagi Y, et al.
- Journal Title
  
  Ann Rheum Dis 64
  
  Pages: 1065-1067
- Data Source
  KAKENHI-PROJECT-16590984
[Journal Article] Molecular analysis of a novel hereditary C3 deficiency with systemic lupus erythematosus.2005
- Author(s)
  Tsukamoto H, Horiuchi T, Kokubo H et al.
- Journal Title
  
  Biochem Biophys Res Commun 330
  
  Pages: 298-304
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590984
[Journal Article] Elevated serum APRIL levels in patients with systemic lupus erythematosus.2005
- Author(s)
  Koyama T, Tsukamoto H, Miyagi Y, Himeji D, Otsuka J, Miyagawa H, Harada M, Horiushi T
- Journal Title
  
  Ann Rheum Dis 64
  
  Pages: 1065-1067
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590984
[Journal Article] Decreased expression of interleukin-21 receptor on peripheral B lymphocytes in systemic lupus erythematosus2005
- Author(s)
  Mitoma H, Horiuchi T, Kimoto Y, Tsukamoto H, et al.
- Journal Title
  
  Int J Mol Med 16
  
  Pages: 609-615
- Data Source
  KAKENHI-PROJECT-16590984
[Journal Article] Raised serum APRIL levels in patients with systemic lupus erythematosus2005
- Author(s)
  Koyama T tsukamoto H, et al.
- Journal Title
  
  Ann Rheum Dis 64
  
  Pages: 1065-1067
- Data Source
  KAKENHI-PROJECT-17591048
[Journal Article] Molecular Analysis of A Novel Hereditary C3 Deficiency with Systemic Lupus Erythematosus.2005
- Author(s)
  Tsukamoto H, Horiuchi T, Kokuba H, Nagae S, Nishizaka H, Sawabe T, Harashima S, Himeji D, Koyama T, Otsuka J, Mitoma H, Kimoto Y, Hashimura C, Kitano E, Kitamura H, Furue H, Harada M
- Journal Title
  
  Biochem.Biophys.Res.Commun 330
  
  Pages: 298-304
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590984
[Journal Article] Infliximab induces potent anti-inflammatory responses by outside-to-inside signals through transmembrane TNF-alpha2005
- Author(s)
  Mitoma H, Horiuchi T, Hatta N, Tsukamoto H, et al.
- Journal Title
  
  Gastroenterology 128
  
  Pages: 376-392
- Data Source
  KAKENHI-PROJECT-16590984
[Journal Article] Raised serum APRIL levels in patients with systemic lupus erythematosus.2005
- Author(s)
  Koyama T, Tsukamoto H, Miyagi Y et al.
- Journal Title
  
  Ann Rheum Dis 64
  
  Pages: 1065-7
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590984
[Journal Article] Infliximab induces potent anti-inflammatory responses by outside-to-inside signals through transmembrane TNF-alpha2005
- Author(s)
  Mitoma H, Horiuchi T, Hatta N, Tsukamoto H et al.
- Journal Title
  
  Gastroenterology 128
  
  Pages: 376-92
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590984
[Journal Article] Molecular analysis of a novel hereditary C3 deficiency with systemic lupus erythematosus.2005
- Author(s)
  Tsukamoto H, Horiuchi T, Kokuba H et al.
- Journal Title
  
  Biochem Biophys Res Commun 330
  
  Pages: 298-304
- Data Source
  KAKENHI-PROJECT-16590984
[Journal Article] Association of a four-amino acid residue insertion polymorphism of the HS1 gene with systemic lupus erythematosus : molecular and functional analysis.2004
- Author(s)
  Otsuka J, Horiuchi T, Yoshizawa S, Tsukamoto H, Sawabe T, Kikuchi Y, Himeji D, Koyama T, Mitoma H, Watanabe T, Harada M
- Journal Title
  
  Arthritis Rheum 50
  
  Pages: 871-881
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590984
[Journal Article] Binding activities of infliximab and etanercept to transmembrane tumor necrosis factor-alpha2004
- Author(s)
  Mitoma H, Horiuchi T, Tsukamoto H et al.
- Journal Title
  
  Gastroenterology 126
  
  Pages: 934-935
- Data Source
  KAKENHI-PROJECT-16590984
[Journal Article] Novel mutations in TNFRSF1A in patients with typical tumor necrosis factor receptor-associated periodic syndrome and with systemic lupus erythematosus in Japanese.2004
- Author(s)
  Horiuchi T, Tsukamoto H, Mitoma H, Miyagawa H, Tamimoto Y, Yoshizawa S, Harada M, Hayashi K, Hashimura C, Oribe M, Okamura S
- Journal Title
  
  Int J Mol Med 14
  
  Pages: 813-818
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590984
[Journal Article] Novel mutations in TNFRSF1A in patients with typical tumor necrosis factor receptor-associated periodic syndrome and with systemic lupus erythematosus in Japanese2004
- Author(s)
  Horiuchi T, Tsukamoto H, Mitoma H et al.
- Journal Title
  
  Int J Mol Med 14
  
  Pages: 813-818
- Data Source
  KAKENHI-PROJECT-16590984
[Journal Article] Association of a four-amino acid residue insertion polymorphism of the HS1 gene with systemic lupus erythematosus : molecular and functional analysis2004
- Author(s)
  Otsuka J, Horiuchi T, Yoshizawa S, Tsukamoto H et al.
- Journal Title
  
  Arthritis Rheum 50
  
  Pages: 871-881
- Data Source
  KAKENHI-PROJECT-16590984
[Journal Article] Elevated serum APRIL levels in patients with systemic lupus erythematosus.
- Author(s)
  Koyama T, Tsukamoto H, Miyagi Y, et al.
- Journal Title
  
  Ann Rheum Dis (in press)
- Data Source
  KAKENHI-PROJECT-16590984
[Journal Article] Molecular analysis of a novel hereditary C3 deficiency with systemic lupus erythematosus.
- Author(s)
  Tsukamoto H, Horiuchi T, Kokuba H et al.
- Journal Title
  
  Biochem Biophys Res Commun (in press)
- Data Source
  KAKENHI-PROJECT-16590984
[Journal Article] A Phase I-II trial of autologous peripheral blood stem cell transplantation in the treatment of refractory autoimmune disease
- Author(s)
  Tsukamoto H, Nagafuji K, Horiuchi T, et al.
- Journal Title
  
  Ann Rheum Dis (印刷中)
- Data Source
  KAKENHI-PROJECT-16590984
[Journal Article] Analysis of immune reconstitution after autologous CD34+ stem/progenitor cell transplantation for systemic sclerosis : predominant reconstitution of Th1 CD4+ T cells.
- Author(s)
  Tsukamoto H, Nagafuji K, Horiuchi T, et al
- Journal Title
  
  Rheumatology
  
  Volume: (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591266
[Presentation] 関節リウマチの治療　病理・病態・バイオマーカー一般血液検査値による関節リウマチに対する生物製剤治療効果予測の可能性2017
- Author(s)
  中川仁, 小山芳伸, 川上純, 植木幸孝, 塚本浩, 永野修司, 内野愛弓, 大田俊行, 赤星光輝, 綾野雅宏, 三苫弘喜, 木本泰孝, 有信洋二郎, 赤司浩一, 堀内孝彦, 新納宏昭
- Organizer
  第61回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-15K09527
[Presentation] 関節リウマチ患者のリンパ球サブセットに対するアバタセプトの経時的作用2017
- Author(s)
  三嶋耕司, 大田俊一郎, 井上靖, 吉澤誠司, 吉澤滋, 永野修司, 西坂浩明, 澤部琢哉, 押領司健介, 多田芳史, 小山芳伸, 綾野雅宏, 木本泰孝, 三苫弘喜, 赤星光輝, 有信洋二郎, 大塚毅, 上田章, 大田俊行, 中島衡, 塚本浩, 赤司浩一, 堀内孝彦, 新納宏昭
- Organizer
  第61回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-15K09527
[Presentation] リウマチ性疾患の動物モデルコラーゲン誘導関節炎モデルマウスにおける自然リンパ球の分化と機能に関する検討2017
- Author(s)
  Author：高木綾子, 有信洋二郎, 大塚恭子, 入野健佑, 押領司大助, 大田友里, 久本仁美, 綾野雅宏, 木本泰孝, 三苫弘喜, 赤星光輝, 塚本浩, 赤司浩一, 堀内孝彦, 新納宏昭
- Organizer
  第61回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-15K09527
[Presentation] 膠原病の難治性病態びまん皮膚硬化型全身性強皮症に対する造血幹細胞移植療法の理論的根拠と実際.2016
- Author(s)
  塚本浩
- Organizer
  第60回日本リウマチ学会総会・学術集会
- Place of Presentation
  横浜
- Year and Date
  2016-04-21
- Data Source
  KAKENHI-PROJECT-15K09527
[Presentation] 膠原病・リウマチ治療の最近の進歩2016
- Author(s)
  塚本浩
- Organizer
  第65回共済医学会
- Place of Presentation
  横浜
- Year and Date
  2016-10-19
- Data Source
  KAKENHI-PROJECT-15K09527
[Presentation] 難治性皮膚筋炎に対する自己造血幹細胞移植の長期成績2015
- Author(s)
  塚本　浩、綾野雅宏、新納宏昭、有信洋二郎、赤星光輝、三苫弘喜、田中淳、大田俊一郎、植木尚子、久本仁美、上田　彰、廣崎友里、押領司大助、赤司浩一
- Organizer
  第59回日本リウマチ学会
- Place of Presentation
  名古屋市
- Year and Date
  2015-04-23
- Data Source
  KAKENHI-PROJECT-15K09527
[Presentation] 難治性自己免疫疾患に対する造血幹細胞移植療法ーその基礎と臨床ー2013
- Author(s)
  塚本　浩、堀内孝彦
- Organizer
  第41回日本臨床免疫学会
- Place of Presentation
  下関
- Data Source
  KAKENHI-PROJECT-24591465
[Presentation] 難治性自己免疫疾患に対する造血幹細胞移植療法-その基礎と臨床-2013
- Author(s)
  塚本浩、堀内孝彦
- Organizer
  第41回日本臨床免疫学会総会
- Place of Presentation
  下関
- Year and Date
  2013-11-29
- Data Source
  KAKENHI-PROJECT-23591464
[Presentation] 全身性硬化症に対するCD34陽性細胞純化及び非純化自己造血幹細胞移植：4年間の比較2013
- Author(s)
  塚本　浩、堀内孝彦、綾野雅宏、新納宏昭、有信洋二郎1、赤星光輝、上田尚靖、田中淳、大田俊一郎、植木尚子、久本仁美、上田　彰、廣崎友里、押領司大助、赤司浩一
- Organizer
  第58回日本リウマチ学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24591465
[Presentation] Seven-year follow-up of autologous hematopoietic stem cell transplantation for severe systemic sclerosis2013
- Author(s)
  Tsukamoto H, Horiuchi H, Miyamoto T, Niiro H, Arinobu Y, Akahosh Mi, Masahiro Ayano, Atsushi Tanaka, Naoyasu Ueda, Koichi Akashi
- Organizer
  Annual European Congress of Rheumatology 2013
- Place of Presentation
  Madrid, Spain
- Data Source
  KAKENHI-PROJECT-24591465
[Presentation] 全身性硬化症に対する自己造血幹細胞移植の長期成績2012
- Author(s)
  塚本　浩、堀内孝彦、綾野雅宏、新納宏昭、有信洋二郎1、井上　靖、上田尚靖、田中淳、大田俊一郎、植木尚子、久本仁美、上田　彰、古川牧緒、原田実根2、赤司浩一
- Organizer
  第57回日本リウマチ学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24591465
[Presentation] Long-term follow-up of autologous hematopoietic stem cell transplantation for severe systemic sclerosis2012
- Author(s)
  Hiroshi Tsukamoto, Takahiko Horiuchi, Toshihiro Miyamoto, Hiroaki Niiro, Yojiro Arinobu, Yasushi Inoue, Masahiro Ayano, Atsushi Tanaka, Naoyasu Ueda, Mine Harada1, Koichi Akashi
- Organizer
  Annual European Congress of Rheumatology 2012
- Place of Presentation
  Berlin, Germany
- Data Source
  KAKENHI-PROJECT-24591465
[Presentation] 全身性硬化症に対するCD34陽性細胞純化及び非純化自己造血幹細胞移植2011
- Author(s)
  塚本浩、堀内孝彦、新納宏昭、他
- Organizer
  第55回日本リウマチ学会総会
- Place of Presentation
  神戸市
- Year and Date
  2011-07-20
- Data Source
  KAKENHI-PROJECT-21591266
[Presentation] CD34-selected and unmanipulated autologous hematopoietic stem cell transplantation for severe systemic sclerosis2011
- Author(s)
  Tsukamoto H, Horiuchi T, Miyamoto T, et al
- Organizer
  Annual European Congress of Rheumatology
- Place of Presentation
  London, UK
- Year and Date
  2011-05-27
- Data Source
  KAKENHI-PROJECT-21591266
[Presentation] CD34-selected and unmanipulated autologous hematopoietic stem cell transplantation for severe systemic sclerosis2011
- Author(s)
  Tsukamoto H, et al
- Organizer
  Annual European Congress of Rheumatology 2011
- Place of Presentation
  London,英国
- Year and Date
  2011-05-27
- Data Source
  KAKENHI-PROJECT-21591266
[Presentation] 全身性硬化症に対する大量免疫抑制療法と自己造血幹細胞移植2010
- Author(s)
  塚本浩、堀内孝彦、三苫弘喜、他
- Organizer
  第54回日本リウマチ学会総会
- Place of Presentation
  神戸市
- Year and Date
  2010-04-24
- Data Source
  KAKENHI-PROJECT-21591266
[Presentation] Autologous hematopoietic stem cell transplantation for severe systemic sclerosis2010
- Author(s)
  Tsukamoto H, Horiuchi T, Miyamoto T, et al
- Organizer
  long-term follow-up analysis of immune reconstitution. Annual European Congress of Rheumatology
- Place of Presentation
  Rome. Italy
- Year and Date
  2010-06-18
- Data Source
  KAKENHI-PROJECT-21591266
[Presentation] 全身性硬化症に対する大量免疫抑制療法と自己末梢血純化CD34陽性細胞移植:術後5年間の臨床成績と免疫学的検討2009
- Author(s)
  塚本浩, 他
- Organizer
  日本リウマチ学会総会
- Place of Presentation
  東京
- Year and Date
  2009-04-24
- Data Source
  KAKENHI-PROJECT-21591266
[Presentation] 全身性硬化症に対する大量免疫抑制療法と自己末梢血純化CD34陽性細胞移植:術後5年間の臨床成績と免疫学的検討2009
- Author(s)
  塚本浩、堀内孝彦、三苫弘喜、他
- Organizer
  第53回日本リウマチ学会総会
- Place of Presentation
  東京
- Year and Date
  2009-04-24
- Data Source
  KAKENHI-PROJECT-21591266
[Presentation] 全身性硬化症に対する大量免疫抑制療法と非純化自己末梢血細胞移植の短期成績2009
- Author(s)
  塚本浩、堀内孝彦、三苫弘喜、他
- Organizer
  第53回日本リウマチ学会総会
- Place of Presentation
  東京
- Year and Date
  2009-04-24
- Data Source
  KAKENHI-PROJECT-21591266
[Presentation] 滑膜線維芽細胞におけるAPRIL発現2007
- Author(s)
  高橋美聡、塚本浩、堀内孝彦, 他
- Organizer
  第51回日本リウマチ学会総会
- Place of Presentation
  東京
- Year and Date
  2007-04-26
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591113
[Presentation] 滑膜線維芽細胞におけるAPRIL発現2007
- Author(s)
  高橋美聡, 塚本浩, 堀内孝彦, 他
- Organizer
  第51回日本リウマチ学会
- Place of Presentation
  横浜
- Year and Date
  2007-04-26
- Data Source
  KAKENHI-PROJECT-18591113
[Presentation] High-dose immune suppressive therapy and autologous peripheral blood stem cell transplantation in systemic sclerosis : analysis of immune reconstitution2006
- Author(s)
  Tsukamoto, H, Nagafuji, K, Horiuchi, T, Nakashima, H, Harada, M
- Organizer
  Annual meeting of American college of rheumatology
- Place of Presentation
  Washington, DC
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591113
[Presentation] Comparison of CD34-selected and unmanipulated autologous hematopoietic stem cell transplantation for systemic sclerosis: Four-year follow-up results
- Author(s)
  Tsukamoto H, Ayano M, Miyamoto T, Niiro H, Arinobu Y, Akahoshi M, Akashi K
- Organizer
  Annual European Congress of Rheumatology 2014
- Place of Presentation
  Paris, France
- Year and Date
  2014-06-11 – 2014-06-14
- Data Source
  KAKENHI-PROJECT-24591465
[Presentation] 難治性自己免疫疾患に対する造血幹細胞移植療法　－その基礎と臨床－
- Author(s)
  塚本浩、堀内孝彦
- Organizer
  第41回日本臨床免疫学会シンポジウム
- Place of Presentation
  下関
- Invited
- Data Source
  KAKENHI-PROJECT-23591464
[Presentation] Role of BAFF and APRIL in differentiation to plasmablast from human peripheral B cells
- Author(s)
  Uchino, A, Tsukamoto, H, Horiuchi, T, Mitoma, H, Taminoto, Y, Kimoto, Y, Oryoji, K, Furukawa, M, To, K, Harada, M
- Organizer
  The 51th Annual meeting of Japan college of rheumatology
- Place of Presentation
  Tokyo
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591113
[Presentation] 感染を繰り返した先天性補体C3欠損症の遺伝子解析
- Author(s)
  塚本　浩、藤健太郎、三苫弘喜、新納宏昭、有信洋二郎、赤星光輝、赤司浩一、北野悦子、畑中道代、北村　肇、堀内孝彦
- Organizer
  第51回補体シンポジウム
- Place of Presentation
  神戸
- Year and Date
  2014-08-21 – 2014-08-22
- Data Source
  KAKENHI-PROJECT-24591465
[Presentation] High-dose cyclophosphamide and autologous peripheral blood stem cell transplantation for severe scleroderma clinical results and analysis of immune reconstitution
- Author(s)
  Tsukamoto, H, Nagafuji, K, Horiuchi, T, Harada, M
- Organizer
  International workshop on scleroderma
- Place of Presentation
  Tokyo
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591113
[Presentation] 造血幹細胞移植による全身性強皮症の治療
- Author(s)
  塚本　浩
- Organizer
  第58回日本リウマチ学会学術集会
- Place of Presentation
  東京
- Year and Date
  2014-04-24 – 2014-04-26
- Data Source
  KAKENHI-PROJECT-24591465
[Presentation] Expression of APRIL in svnovial fibroblast-like cells
- Author(s)
  Takahashi, M, Tsukamoto, H, Horiuchi, T, Mitoma, H, Uchino, A, Kimoto, Y, Oryoji, K, Furukawa, M, To, K, Harada, M
- Organizer
  The 51th Annual meeting of Japan college of rheumatology
- Place of Presentation
  Tokyo
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591113

1. HORIUCHI TAKAHIKO (90219212)

# of Collaborated Projects: 9 results

# of Collaborated Products: 87 results
2. TAHIRA Tomoko (50155230)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. OHARA Osamu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. TANAKA Takayuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. ARINOBU Yojiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
6. NIIRO Hiroaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 西小森隆太

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 藤田尚志

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 赤司浩一

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
10. 東條有伸

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

TSUKAMOTO Hiroshi 塚本 浩

Research Projects

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Co-Researchers

Investigation of the role of CD226+CD8+T cells in the pathogenesis of systemic sclerosis and an application to therapyPrincipal Investigator

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Identification of the new function of TNF induced by intramembrane proteases and the application to regulate inflammatory diseases.Principal Investigator

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Clarification of the mechanisms of intracellular trafficking of TNF

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Development of a new stem cell transplantation regimen in the treatment of refractory autoimmune diseasesPrincipal Investigator

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Functional analysis of BAFF, APRIL and their receptors, and the study of their role in the pathogenesis of autoimmune diseasePrincipal Investigator

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Functional analyses for transmembrane TNF-alpha

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Functional analysis of APRIL and BAFF, and the study of their role in the pathogenesis of autoimmune diseasePrincipal Investigator

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The association of the gene polymorphism of APRIL and BAFF with autoimmune diseases : Functional analysisPrincipal Investigator

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Analysis of the function of membrane TNF-α

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Functional analysis of membrane TNF-α

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[Book] 見逃すと怖い膠原病100の質問2014

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[Book] 免疫・アレルギー疾患イラストレイテッド2013

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[Book] 補体への招待2011

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[Book] 補体への招待2011

TSUKAMOTO Hiroshi 塚本浩