NAKAJIMA Mitsunari 中島光業

… Alternative Names

中島光業ナカジマミツナリ

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Researcher Number	70311404
Other IDs
Affiliation (Current)	2025: 松山大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2017 – 2023: 松山大学, 薬学部, 教授 2018: 松山大学, 薬学部, 准教授 2007 – 2016: Matsuyama University, Dep. Of Pharmaceutical Pharmacology, Associate Professor 2006: 松山大学, 薬学部, 助教授 2005: Tokyo Metropolitan Foundation for Research on Aging and Promotion of Human Welfare, Tokyo Metropolitan Institute of Gerontology, Research Scientist in chief, 東京都老人総合研究所, 主任研究員 2004: 財団法人東京都高齢者研究, 福祉振興財団・東京都老人総合研究所, 研究員
Review Section/Research Field	Principal Investigator Basic Section 59040:Nutrition science and health science-related / Embryonic/Neonatal medicine / Pediatrics / Endocrinology Except Principal Investigator Basic Section 38050:Food sciences-related / Basic Section 59040:Nutrition science and health science-related / Eating habits / Cerebral neurosurgery / Orthopaedic surgery
Keywords	Principal Investigator アルツハイマー病 / プレセニリン1 / ドラッグリポジショニング / SIRT1 / 健康寿命延伸物質 / カロリー制限模倣物 / Alzheimer's disease / presenilin 1 / ノックアウトマウス / 自閉症 … More / 神経堤 / 長寿命遺伝子 / 健康寿命 / カロリー制限模放物 / 発達小児科学 / オキシトシン / dTgマウス / knockout mouse / skull vault / neural crest / 頭蓋骨 / congenital heart disease / morphogenesis / heart / knockout mice / 心臓神経堤細胞 / プレセニリン / 先天性心疾患 / 形態形成 / 心臓 / 社会性行動 / 性差 / モデルマウス / 成長ホルモン / 下垂体 … More Except Principal Investigator 脳卒中 / 柑橘成分 / SHRSP / ダブルコンジェニック / 脳虚血 / オーラプテン / 河内晩柑 / 抗炎症作用 / 柑橘 / 認知機能障害 / 脳神経疾患 / 脳梗塞 / 脳虚血モデルマウス / PC12細胞 / Neuro2a細胞 / BBBスコア / 柑橘化合物 / BBB スコア / 脊髄損傷モデル動物 / ヘプタメトキシフラボン / 化合物ライブラリー / in silico薬物設計 / ニューロトロフィン受容体 / ニューロトロフィン / ソーチリン / RAP(receptor-associated protein) / p75受容体 / アポトーシス / ニューロトロフィン前駆体 / 脊髄損傷修復 Less

ダブルコンジェニックSHRSP/Izmを用いた河内晩柑果皮の脳血管障害防御機構の解析
- Principal Investigator
  
  奥山聡
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38050:Food sciences-related
- Research Institution
  Matsuyama University
健康寿命延伸物質の探索　～ドラッグリポジショニングの活用～Principal Investigator
- Principal Investigator
  
  中島光業
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Matsuyama University
Protection mechanism of citrus components against brain dysfunction using double congenic SHRSP/Izm
- Principal Investigator
  
  Okuyama Satoshi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Matsuyama University
A proposed novel method for screening caloric restriction mimetics and its applicationPrincipal Investigator
- Principal Investigator
  
  Nakajima Mitsunari
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Matsuyama University
The effects of citrus-related compounds on global cerebral ischemic injury in SHRSP.
- Principal Investigator
  
  OKUYAMA SATOSHI
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Eating habits
- Research Institution
  Matsuyama University
Phenotypes Associated with Psychiatric Disorders are Sex-Specific in a Mutant Mouse LinePrincipal Investigator
- Principal Investigator
  
  Nakajima Mitsunari
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Matsuyama University
Analysis of a mouse model showing autism-related behavioral abnormalitiesPrincipal Investigator
- Principal Investigator
  
  Nakajima Mitsunari
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Matsuyama University
Effect of citrus components on the injured spinal cord
- Principal Investigator
  
  FURUKAWA Yoshiko
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Matsuyama University
Restricted growth and insulin-like growth factor-1 deficiency in mice lacking presenilin-1 in the neural crest cell lineagePrincipal Investigator
- Principal Investigator
  
  NAKAJIMA Mitsunari
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Endocrinology
- Research Institution
  Matsuyama University
脊髄損傷修復への応用をめざした新たな神経保護薬の創生
- Principal Investigator
  
  古川美子
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Matsuyama University
A causative gene for early-onset familial Alzheimer's disease, presenilin 1, and skull vault formationPrincipal Investigator
- Principal Investigator
  
  MITSUNARI Nakajima
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Embryonic/Neonatal medicine
- Research Institution
  Matsuyama University
A causative gene for early-onset familial Alzheimer's disease, presenilin 1, and cardiac morphogenesisPrincipal Investigator
- Principal Investigator
  
  NAKAJIMA Mitsunari
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Embryonic/Neonatal medicine
- Research Institution
  Tokyo Metropolitan Foundation for Research on Aging and Promotion of Human Welfare

[Journal Article] Sulconazole induces pyroptosis promoted by interferon-γ in monocyte/macrophage lineage cells2024
- Author(s)
  Miyawaki S, Sawamoto A, Okuyama S, Nakajima M
- Journal Title
  
  J. Pharmacol. Sci.
  
  Volume: 154 Issue: 3 Pages: 166-174
- DOI
  10.1016/j.jphs.2024.01.006
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K11819
[Journal Article] Tipepidine activates AMPK and improves adipose tissue fibrosis and glucose intolerance in high‐fat diet‐induced obese mice2024
- Author(s)
  Sawamoto Atsushi、Okada Madoka、Matsuoka Nanako、Okuyama Satoshi、Nakajima Mitsunari
- Journal Title
  
  The FASEB Journal
  
  Volume: 38 Issue: 5
- DOI
  10.1096/fj.202301861rr
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K14366, KAKENHI-PROJECT-22K11819
[Journal Article] N-Caffeoyltryptophan enhances adipogenic differentiation in preadipocytes and improves glucose tolerance in mice.2023
- Author(s)
  Sawamoto A, Doi K, Amakura Y, Nakanishi M, Okuyama S, Nakajima M.
- Journal Title
  
  Biochim Biophys Acta Gen Subj
  
  Volume: 1867 Issue: 2 Pages: 130277-130277
- DOI
  10.1016/j.bbagen.2022.130277
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K11819, KAKENHI-PROJECT-20K16018
[Journal Article] Cynandione A causes a dynamic change in SIRT1 nuclear trafficking via PKA signaling and beige adipocyte differentiation in 3T3-L1 cells2021
- Author(s)
  Atsushi Sawamoto, Asami Kanazaki, Masayuki Nakanishi, Yoshiaki Amakura, Morio Yoshimura, Nahoko Uchiyama, Takashi Hakamatsuka, Satoshi Okuyama, Mitsunari Nakajima
- Journal Title
  
  Eur J Pharmacol
  
  Volume: 909 Pages: 174382-174382
- DOI
  10.1016/j.ejphar.2021.174382
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K11707
[Journal Article] T-Cell Activation-Inhibitory Assay to Screen Caloric Restriction Mimetics Drugs for Drug Repositioning2021
- Author(s)
  Ishikawa Shouma、Sawamoto Atsushi、Okuyama Satoshi、Nakajima Mitsunari
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 44 Issue: 4 Pages: 550-556
- DOI
  10.1248/bpb.b20-00889
- NAID
  130008014300
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2021-04-01
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K11707
[Journal Article] Cynandione A induces adipogenesis and beige adipocyte-related phenotype in 3T3-L1 cells2020
- Author(s)
  Sawamoto Atsushi、Kanazaki Asami、Amakura Yoshiaki、Yoshimura Morio、Masumoto Naoko、Uchiyama Nahoko、Hakamatsuka Takashi、Okuyama Satoshi、Furukawa Yoshiko、Nakajima Mitsunari
- Journal Title
  
  Phytochemistry Letters
  
  Volume: 39 Pages: 84-89
- DOI
  10.1016/j.phytol.2020.07.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K11707
[Journal Article] Identification of the characteristic components in walnut and anti-inflammatory effect of glansreginin A as an indicator for quality evaluation.2020
- Author(s)
  Haramiishi R, Okuyama S, Yoshimura M, Nakajima M, Furukawa Y, Ito H, Amakura Y.
- Journal Title
  
  Biosci Biotechnol Biochem.
  
  Volume: 84(1) Issue: 1 Pages: 187-197
- DOI
  10.1080/09168451.2019.1670046
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K11707
[Journal Article] Heptamethoxyflavone inhibits adipogenesis via enhancing PKA signaling.2019
- Author(s)
  Sawamoto A, Nakanishi M, Okuyama S, Furukawa Y, Nakajima M.
- Journal Title
  
  Eur J Pharmacol.
  
  Volume: 865 Pages: 172758-172758
- DOI
  10.1016/j.ejphar.2019.172758
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K11707
[Journal Article] T-cell activation-inhibitory assay: a proposed novel method for screening caloric restriction mimetics2019
- Author(s)
  Iura S, Ojima Y, Amakura Y, Yoshimura M, Sawamoto A, Okuyama S, Furukawa Y, Nakajima M.
- Journal Title
  
  Biomed. Res.
  
  Volume: 40 Issue: 6 Pages: 235-241
- DOI
  10.2220/biomedres.40.235
- NAID
  130007761174
- ISSN
  0388-6107, 1880-313X
- Year and Date
  2019-12-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K11707
[Journal Article] Phenotypes associated with psychiatric disorders are sex-specific in a mutant mouse line.2016
- Author(s)
  Nakajima M, Watanabe T, Aoki R, Shimizu R, Okuyama S, Furukawa Y.
- Journal Title
  
  Brain Research
  
  Volume: 1652 Pages: 53-61
- DOI
  10.1016/j.brainres.2016.09.037
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16K09977
[Journal Article] 精神疾患様異常行動、聴覚過敏、そして脳内オキシトシン含量の低下を示すマウスの紹介2015
- Author(s)
  中島光業、奥山聡、古川美子
- Journal Title
  
  愛媛県病薬会誌
  
  Volume: 117 Pages: 17-19
- Data Source
  KAKENHI-PROJECT-25461567
[Journal Article] Dilation of the inferior colliculus and hypersensitivity to sound in Wnt1-cre and Wnt1-GAL4 double-transgenic mice.2014
- Author(s)
  Nakajima M, Nishikawa C, Miyasaka Y, Kikkawa Y, Mori H, Tsuruta M, Okuyama S, Furukawa Y.
- Journal Title
  
  Neurosci Lett.
  
  Volume: 566 Pages: 236-240
- DOI
  10.1016/j.neulet.2014.02.061
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25290038, KAKENHI-PROJECT-25461567
[Journal Article] A comparative study of axon-surrounding cells in the two nasal nerve tracts from mouse olfactory epithelium and vomeronasal organ.2013
- Author(s)
  Nakajima M, Tsuruta M, Mori H, Nishikawa C, Okuyama S, Furukawa Y.
- Journal Title
  
  Brain Res.
  
  Volume: 1503 Pages: 16-23
- DOI
  10.1016/j.brainres.2013.01.053
- Data Source
  KAKENHI-PROJECT-23659699
[Journal Article] Psychiatric disorder-related abnormal behavior and habenulointerpeduncular pathway defects in Wnt1-cre and Wnt1-GAL4 double transgenic mice.2013
- Author(s)
  Nakajima M, Mori H, Nishikawa C, Tsuruta M, Okuyama S, Furukawa Y.
- Journal Title
  
  J. Neurochem.
  
  Volume: 124(2) Issue: 2 Pages: 241-9
- DOI
  10.1111/jnc.12085
- Data Source
  KAKENHI-PROJECT-23659699
[Journal Article] Anti-inflammatory and neuroprotective effect of auraptene, a citrus coumarin, following cerebral global ischemia in mice.2013
- Author(s)
  Okuyama S, Minami S, Shimada N, MakihataN, Nakajima M, Furukawa Y.
- Journal Title
  
  Eur.J.Pharmacol.
  
  Volume: 699 Issue: 1-3 Pages: 118-123
- DOI
  10.1016/j.ejphar.2012.11.043
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659699, KAKENHI-PROJECT-23700941
[Journal Article] Isolation and characterization of activators of ERK/MAPK from Citrus plants.2012
- Author(s)
  Furukawa Y, Okuyama S, Amakura Y, Watanabe S, Fukata T, Nakajima M, Yoshimura M, Yoshida T.
- Journal Title
  
  Int. J. Mol. Sci.
  
  Volume: 13 Issue: 2 Pages: 1832-1845
- DOI
  10.3390/ijms13021832
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659699, KAKENHI-PROJECT-23700941
[Journal Article] Effect of Citrus Polymethoxyfavones on Neuritogenesis in Neuroblastoma Cells.2012
- Author(s)
  Furukawa Y, Watanabe S, Okuyama S, Amakura Y, Yoshimura M, Yoshida T, Nakajima M.
- Journal Title
  
  Biointerface Res. Applied Chem.
  
  Volume: 2 Pages: 432-437
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659699
[Journal Article] Heptamethoxyflavone, a citrus flavonoid, enhances brain-derived neurotrophic factor production and neurogenesis in the hippocampus following cerebral global ischemia in mice.2012
- Author(s)
  Okuyama S, Shimada N, Kaji M, Morita M, Miyoshi K, Minami S, Amakura Y, Yoshimura M, Yoshida T, Watanabe S, Nakajima M, FurukawaY.
- Journal Title
  
  Neurosci. Lett.
  
  Volume: 528 Issue: 2 Pages: 190-195
- DOI
  10.1016/j.neulet.2012.08.079
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659699, KAKENHI-PROJECT-23700941
[Journal Article] Effect of citrus polymethoxyfavones on neuritogenesis in neuroblastoma cells.2012
- Author(s)
  Furukawa Y, Watanabe S, Okuyama S, Amakura Y, Yoshimura M, Yoshida T, Nakajima M.
- Journal Title
  
  Biointerface Res. Applied Chem.
  
  Volume: 2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659699
[Journal Article] Neurotrophic effect of citrus auraptene: neuritegenic activity in PC12 cells.2012
- Author(s)
  Furukawa Y, Watanabe S, Okuyama S,Nakajima M.
- Journal Title
  
  Int. J. Mol. Sci.
  
  Volume: 13 Issue: 5 Pages: 5338-5347
- DOI
  10.3390/ijms13055338
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659699, KAKENHI-PROJECT-23700941
[Journal Article] Hydrocephalus and abnormal subcommissural organ in mice lacking presenilin-1 in Wnt1 cell lineages.2011
- Author(s)
  Nakajima M, Matsuda K, Miyauchi N, Fukunaga Y, Watanabe S, Okuyama S, Perez J, Fernandez-Llebrez P, Shen J, Furukawa Y.
- Journal Title
  
  Brain Res. 1382巻
  
  Pages: 275-281
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591104
[Journal Article] Hydrocephalus and abnormal subcommissural organ in mice lacking presenilin-l in Wntl cell lineages.2011
- Author(s)
  Mitsunari Nakajima
- Journal Title
  
  Brain Res.
  
  Volume: 1382 Pages: 275-281
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591104
[Journal Article] Estrogen Stimulates Proliferation and Differentiation of Neural Stem/Progenitor Cells through Different Signal Transduction Pathways.2010
- Author(s)
  Okada M, Makino A, Nakajima M, Okuyama S, Furukawa S, Furukawa Y.
- Journal Title
  
  Int J Mol Sci. 11巻
  
  Pages: 4114-4123
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591104
[Journal Article] 4-Methylcatechol-induced heme oxygenase-1 exerts a protective effect against oxidative stress in cultured neural stem/progenitor cells via PI3 kinase/Akt pathway2010
- Author(s)
  Furukawa Y, Urano T, Minamimura M, Nakajima M, Okuyama S, Furukawa S.
- Journal Title
  
  Biomedical Research 31
  
  Pages: 45-52
- NAID
  130004903782
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591104
[Journal Article] 4-Methylcatechol-induced heme oxygenase-1 exerts a protective effect against oxidative stress in cultured neural stem/progenitor cells via PI3 kinase/Akt pathway2010
- Author(s)
  Yoshiko Furukawa, Tomomi Urano, Misato Minamimura, Mitsunari Nakajima, Satoshi Okuyama, Shoei Furukawa
- Journal Title
  
  Biomedical Research 31
  
  Pages: 45-52
- NAID
  130004903782
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20659239
[Journal Article] 4-Methylcatechol-induced heme oxygenase-1 exerts a protective effect against oxidative stress in cultured neural stem/progenitor cells via PI3 kinase/Akt pathway.2010
- Author(s)
  Furukawa Y, Urano T, Minamimura M, Nakajima M, Okuyama S, Furukawa S.
- Journal Title
  
  Biomed Res. 31巻
  
  Pages: 45-52
- NAID
  130004903782
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591104
[Journal Article] Restricted growth and insulin-like growth factor-1 deficiency in mice lacking presenilin-1 in the neural crest cell lineage2009
- Author(s)
  Mitsunari Nakajima, Sono Watanabe, Satoshi Okuyama, Jie Shen, Yoshiko Furukawa
- Journal Title
  
  International Journal of Developmental Neuroscience 27
  
  Pages: 837-843
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20659239
[Journal Article] Restricted growth and insulin-like growth factor-1 deficiency in mice lacking presenilin-1 in the neural crest cell lineage.2009
- Author(s)
  Nakajima M, Watanabe S, Okuyama S, Shen J, Furukawa Y
- Journal Title
  
  Int J Dev Neurosci. 27巻
  
  Pages: 837-843
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591104
[Journal Article] Restricted growth and insulin-like growth factor-1 deficiency in mice lacking presenilin-1 in the neural crest cell lineage2009
- Author(s)
  Nakajima M, Watanabe S, Okuyama S, Shen J, Furukawa Y.
- Journal Title
  
  International Journal of Developmental Neuroscience 27
  
  Pages: 837-843
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591104
[Journal Article] Effects of estrogens on proliferation and differentiation of neuralstem/progenitor cells.2008
- Author(s)
  Okada M, Murase K, Makino A, Nakajima M, Kaku T, Furukawa S, Furukawa Y.
- Journal Title
  
  Biomedical Research 29
  
  Pages: 163-170
- NAID
  130004470710
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20659239
[Journal Article] Effects of estrogens on proliferation and differentiation of neural stem/progenitor cells.2008
- Author(s)
  Okada M, Murase K, Makino A, Nakajima M, Kaku T, Furukawa S, Furukawa Y
- Journal Title
  
  Biomed Res. 29巻
  
  Pages: 163-170
- NAID
  130004470710
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591104
[Journal Article] Effects of estrogens on proliferation and differentiation of neural stem/progenitor cells.2008
- Author(s)
  Okada M, Murase K, Makino A, Nakajima M, Kaku T, Furukawa s, Furukawa Y.
- Journal Title
  
  Biomedical Research 29
  
  Pages: 163-170
- NAID
  130004470710
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591104
[Journal Article] Presenilin-1 controls the growth and differentiation of endothelial progenitor cells through its b-catenin-binding region.2006
- Author(s)
  Nakajima, M., Ogawa, M., Shimoda, Y., Hiraoka, S., Iida, M., Koseki, H., Shirasawa, T., Furukawa K.
- Journal Title
  
  Cell Biol.Int. 30
  
  Pages: 239-243
- Data Source
  KAKENHI-PROJECT-18591227
[Journal Article] Accelerated acquisition of permeability barrier function in the skin of presenilin-l-deficient embryos.(Concerned)2006
- Author(s)
  Nakajima M, Ogawa M, Shimoda Y, Koseki H, Shirasawa T, Furukawa K.
- Journal Title
  
  Arch. Dermatol. Res. 298
  
  Pages: 339-345
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591227
[Journal Article] Accelerated acquisition of permeability barrier function in the skin of presenilin-1-deficient embryos.2006
- Author(s)
  Nakajima M, Ogawa M, Shimoda Y, Koseki H, Shirasawa T, Furukawa K.
- Journal Title
  
  Arch.Dermatol.Res. 298
  
  Pages: 339-345
- Data Source
  KAKENHI-PROJECT-18591227
[Journal Article] Presenilin-1 controls the growth and differentiation of endothelial progenitor cells through its b-catenin-binding region.(Concerned)2006
- Author(s)
  Nakajima, M., Ogawa, M., Shimoda, Y., Hiraoka, S., Iida, M., Koseki, H., Shirasawa, T., Furukawa K.
- Journal Title
  
  Cell Biol. Int. 30
  
  Pages: 239-243
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591227
[Journal Article] Presenilin-1 controls the growth and differentiation of endothelial progenitor cells through its b-catenin-binding region2006
- Author(s)
  Nakajima, M., Ogawa, M., Shimoda, Y., Hiraoka, S., Iida, M., Koseki, H., Shirasawa, T., Furukawa K.
- Journal Title
  
  Cell Biol.Int. 30
  
  Pages: 239-243
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591227
[Journal Article] Accelerated acquisition of permeability barrier function in the skin of presenilin-1-deficient embryos2006
- Author(s)
  Nakajima M, Ogawa M, Shimoda Y, Koseki H, Shirasawa T, Furukawa K.
- Journal Title
  
  Arch.Dermatol.Res. 298
  
  Pages: 339-345
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591227
[Journal Article] Presenilin-1 controls the growth and differentiation of endothelial progenitor cells through its beta-catenin-binding region.2005
- Author(s)
  Nakajima, M.
- Journal Title
  
  Cell Biol.Int. (In press)
- Data Source
  KAKENHI-PROJECT-16591083
[Journal Article] Presenilin-1 controls the growth and differentiation of endothelial progcnitor cells through its beta-catcnin-binding region.2005
- Author(s)
  Nakajima, M.
- Journal Title
  
  Cell Biol. Int. In press
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591083
[Journal Article] Presenilin 1 is essential for cardiac morphogenesis.2004
- Author(s)
  Nakajima, M.
- Journal Title
  
  Dev. Dyn. 230
  
  Pages: 795-799
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591083
[Journal Article] Presenilin 1 is essential for cardiac morphogenesis.2004
- Author(s)
  Nakajima M., Moriizumi E., Koseki H., Shirasawa T.
- Journal Title
  
  Dev.Dyn. 230
  
  Pages: 795-799
- Data Source
  KAKENHI-PROJECT-16591083
[Journal Article] Presenilin 1 is essential for cardiac morphogenesis.2004
- Author(s)
  Nakajima, M. et al.
- Journal Title
  
  Dev.Dyn. 230(4)
  
  Pages: 795-799
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591083
[Journal Article] Presenilin-1-deficient neurons are nitroc oxide-dependently killed by hydrogen peroxide in vitro.2004
- Author(s)
  Nakajima, M.
- Journal Title
  
  Neuroscience 125
  
  Pages: 563-568
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591083
[Journal Article] Presenilin-1-deficient neurons are nitric oxide-dependently killed by hydrogen peroxide in vitro.2004
- Author(s)
  Nakajima, M, Shirasawa, T.
- Journal Title
  
  Neuroscience 125(3)
  
  Pages: 563-568
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591083
[Journal Article] Presenilin-1-deficient neurons are nitric oxide-dependently killed by hydrogen peroxide in vitro.2004
- Author(s)
  Nakajima M., Shirasawa T.
- Journal Title
  
  Neuroscience 125
  
  Pages: 563-568
- Data Source
  KAKENHI-PROJECT-16591083
[Journal Article] Presenilin-1 controls the growth and differentiation of endothelial progenitor cells through its beta- catenin-binding region.
- Author(s)
  Nakajima, M. et al.
- Journal Title
  
  Cell Biol.Int. (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591083
[Patent] 脳神経疾患治療、脳神経疾患予防または脳機能改善のための組成物2011
- Inventor(s)
  古川美子・吉田隆志・天倉吉章・奥山聡・中島光業
- Industrial Property Rights Holder
  古川美子
- Industrial Property Number
  2011-213795
- Filing Date
  2011-09-28
- Data Source
  KAKENHI-PROJECT-23659699
[Presentation] SHRSP/IzmおよびダブルコンジェニックSHRSP/Izmに対する柑橘果皮成分の作用解析2023
- Author(s)
  奥山聡、島﨑結子、奥迫優奈、大原浩貴、並河徹、大政俊樹、澤本篤志、中島光業
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-20K11523
[Presentation] SHRSPの脳血管障害に対する柑橘果皮成分の作用メカニズム解析2023
- Author(s)
  永井弘奈、奥山聡、五百木沙弥香、澤本篤志、中島光業
- Organizer
  第62回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会
- Data Source
  KAKENHI-PROJECT-23K05139
[Presentation] リポ多糖誘発敗血症モデルマウスに対するイブジラストの効果2022
- Author(s)
  中島光業、門田尚子、吉田明香里、澤本篤志、奥山聡
- Organizer
  日本薬学会　第１４２年会（名古屋）
- Data Source
  KAKENHI-PROJECT-19K11707
[Presentation] ダブルコンジェニックSHRSP/Izmに対する河内晩柑果皮成分の作用2022
- Author(s)
  奥迫優奈、奥山聡、大原浩貴、島﨑結子、大政俊樹、澤本篤志、中島光業、並河徹
- Organizer
  第61回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会
- Data Source
  KAKENHI-PROJECT-20K11523
[Presentation] 脳卒中易発症ラットの一過性全脳虚血障害に対する河内晩柑果皮成分の神経細胞保護作用2021
- Author(s)
  奥山聡、二宮風雅、大久保優、玉那覇アリサ、永井美穂子、澤本篤志、中島光業、古川美子
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-20K11523
[Presentation] 脳卒中易発症ラットの全脳虚血障害に対するナリンギンおよびヘプタメトキシフラボンの作用2019
- Author(s)
  奥山聡、玉那覇アリサ、大久保優、永井美穂子、澤本篤志、中島光業、古川美子
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-16K00932
[Presentation] SHRSPの全脳虚血障害に対するナリンギンの作用2018
- Author(s)
  玉那覇アリサ、奥山聡、大久保優、冨永知志、澤本篤志、中島光業、古川美子
- Organizer
  第57回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会
- Data Source
  KAKENHI-PROJECT-16K00932
[Presentation] Auraptene acts as an anti-inflammatory and neuroprotective agent in the mouse brain2016
- Author(s)
  S. OKUYAMA, M. MORITA, M. KAJI, K. SHIMAMOTO, Y. OOKIDO, Y. AMAKURA, M. YOSHIMURA, M. NAKAJIMA, Y. FURUKAWA
- Organizer
  Neuroscience 2016
- Place of Presentation
  San Diego, CA, USA
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K00932
[Presentation] 精神疾患様異常行動と聴覚過敏を伴うWnt1-cre, Wnt1-GAL4ダブルトランスジェニックマウスにおける脳内オキシトシン含量の低下2015
- Author(s)
  中島光業、渡部貴司、青木ルイ、清水理誠、奥山聡、古川美子
- Organizer
  日本神経科学会
- Place of Presentation
  神戸
- Year and Date
  2015-07-28
- Data Source
  KAKENHI-PROJECT-25461567
[Presentation] 精神疾患モデルマウスで認められる下丘肥大と聴覚過敏2014
- Author(s)
  中島光業、西川知沙、宮坂勇輝、吉川欣亮、森久倫、鶴田桃子、奥山聡、古川美子
- Organizer
  日本薬学会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-25461567
[Presentation] 柑橘由来成分aurapteneの神経系に及ぼす作用（２）脳虚血疾患モデルに対する脳保護効果2013
- Author(s)
  奥山聡、守田麻由、加地未来、中島光業、古川美子
- Organizer
  日本薬学会第133年会
- Place of Presentation
  神奈川県横浜市
- Data Source
  KAKENHI-PROJECT-23659699
[Presentation] 柑橘由来成分aurapteneの神経系に及ぼす作用（１）培養神経細胞およびPC12細胞に対する作用2013
- Author(s)
  古川美子、奥山聡、渡辺苑、中島光業
- Organizer
  日本薬学会第133年会
- Place of Presentation
  神奈川県横浜市
- Data Source
  KAKENHI-PROJECT-23659699
[Presentation] 柑橘果皮由来成分ヘプタメトキシフラボンの全脳虚血モデルマウスにおけるBDNF産生ならびに神経新生促進作用2013
- Author(s)
  奥山聡、島田直子、天倉吉章、好村守生、中島光業、古川美子
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡市
- Data Source
  KAKENHI-PROJECT-23659699
[Presentation] 柑橘由来成分aurapteneの神経系に及ぼす作用(2)脳虚血疾患モデルに対する脳保護効果2013
- Author(s)
  奥山聡、守田麻由、加地未来、中島光業、古川美子
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-23659699
[Presentation] 柑橘由来成分aurapteneの神経系に及ぼす作用(1)培養神経細胞およびPC12細胞に対する作用2013
- Author(s)
  古川美子、奥山聡、渡辺苑、中島光業
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-23659699
[Presentation] 柑橘果皮由来成分ヘプタメトキシフラボンの全脳虚血モデルマウスにおけるBDNF産生ならびに神経新生促進作用2013
- Author(s)
  奥山聡、島田直子、天倉吉章、好村守生、中島光業、古川美子
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡県福岡市
- Data Source
  KAKENHI-PROJECT-23659699
[Presentation] 柑橘由来脳活性化物質の探索（２）脳虚血障害におけるオーラプテンの脳保護作用2012
- Author(s)
  奥山聡、南仙雅、島田直子、巻幡奈保美、天倉吉章、好村守生、吉田隆志、中島光業、古川美子
- Organizer
  日本薬学会第１３２回年会
- Place of Presentation
  札幌市
- Data Source
  KAKENHI-PROJECT-23659699
[Presentation] 柑橘由来成分aurapteneの脳虚血疾患に対する脳保護効果2012
- Author(s)
  守田麻由、奥山聡、加地未来、中島光業、古川美子
- Organizer
  第51回日本薬学会中四国支部学術大会
- Place of Presentation
  松江市
- Data Source
  KAKENHI-PROJECT-23659699
[Presentation] 柑橘由来成分aurapteneの脳虚血疾患に対する脳保護効果2012
- Author(s)
  守田麻由、奥山聡、加地未来、中島光業、古川美子
- Organizer
  第51回日本薬学会中四国支部学術大会
- Place of Presentation
  島根県松江市
- Data Source
  KAKENHI-PROJECT-23659699
[Presentation] 柑橘由来成分heptamethoxyflavoneの中枢神経系における抗炎症作用の検討2012
- Author(s)
  三好和浩、奥山聡、西川祐貴、天倉吉章、好村守生、吉田隆志、中島光業、古川美子
- Organizer
  第51回日本薬学会中四国支部学術大会
- Place of Presentation
  島根県松江市
- Data Source
  KAKENHI-PROJECT-23659699
[Presentation] 柑橘由来脳活性化物質の探索(1)2012
- Author(s)
  古川美子、奥山聡、渡辺苑、深田貴大、中島光業、天倉吉章、好村守生、吉田隆志
- Organizer
  日本薬学会第132回年会
- Place of Presentation
  札幌市
- Data Source
  KAKENHI-PROJECT-23659699
[Presentation] 「河内晩柑」果皮含有成分の脳虚血障害に対する脳保護作用2012
- Author(s)
  奥山聡、島田直子、渡辺苑、天倉吉章、好村守生、中島光業、古川美子
- Organizer
  第３回宇和島薬剤師会学術大会
- Place of Presentation
  愛媛県宇和島市
- Data Source
  KAKENHI-PROJECT-23659699
[Presentation] 柑橘由来成分heptamethoxyflavoneの中枢神経系における抗炎症作用の検討2012
- Author(s)
  三好和浩、奥山聡、西川祐貴、天倉吉章、好村守生、吉田隆志、中島光業、古川美子
- Organizer
  第51回日本薬学会中四国支部学術大会
- Place of Presentation
  松江市
- Data Source
  KAKENHI-PROJECT-23659699
[Presentation] 河内晩柑果皮含有成分の脳虚血障害に対する脳保護作用2012
- Author(s)
  奥山聡、島田直子、渡辺苑、天倉吉章、好村守生、中島光業、古川美子
- Organizer
  第3回宇和島薬剤師会学術大会(2012年12月16日)
- Place of Presentation
  宇和島市
- Year and Date
  2012-12-16
- Data Source
  KAKENHI-PROJECT-23659699
[Presentation] 柑橘由来脳活性化物質の探索(2)脳虚血障害におけるオーラプテンの脳保護作用2012
- Author(s)
  奥山聡、南仙雅、島田直子、巻幡奈保美、天倉吉章、好村守生、吉田隆志、中島光業、古川美子
- Organizer
  日本薬学会第132回年会
- Place of Presentation
  札幌市
- Data Source
  KAKENHI-PROJECT-23659699
[Presentation] 柑橘由来脳活性化物質の探索（１）2012
- Author(s)
  古川美子、奥山聡、渡辺苑、深田貴大、中島光業、天倉吉章、好村守生、吉田隆志
- Organizer
  日本薬学会第１３２回年会
- Place of Presentation
  札幌市
- Data Source
  KAKENHI-PROJECT-23659699
[Presentation] 愛媛特産柑橘果皮由来成分の脳における抗炎症作用2011
- Author(s)
  津村優一、奥山聡、天倉吉章、好村守生、吉田隆志、中島光業、古川美子
- Organizer
  第50回日本薬学会中四国支部学術大会
- Place of Presentation
  高松市
- Data Source
  KAKENHI-PROJECT-23659699
[Presentation] 愛媛特産柑橘果皮由来成分の脳における抗炎症作用2011
- Author(s)
  津村優一、奥山聡、天倉吉章、好村守生、吉田隆志、中島光業、古川美子
- Organizer
  日本薬学会中国四国支部会
- Place of Presentation
  香川県高松市
- Data Source
  KAKENHI-PROJECT-23659699
[Presentation] 4-メチルカテコールはHO-1発現誘導により神経幹/前駆細胞を酸化ストレスから保護する2010
- Author(s)
  古川美子、浦野友美、南村美里、中島光業、奥山聡、古川昭栄
- Organizer
  日本薬学会
- Place of Presentation
  岡山市
- Year and Date
  2010-03-30
- Data Source
  KAKENHI-PROJECT-20591104
[Presentation] 下垂体成長ホルモン産生細胞の成熟・維持におけるプレセニリン1の働き2009
- Author(s)
  中島光業、奥山聡、渡辺苑、古川美子
- Organizer
  日本薬理学会西南部会
- Place of Presentation
  松山市
- Year and Date
  2009-11-27
- Data Source
  KAKENHI-PROJECT-20591104
[Presentation] 神経堤細胞特異的プレセニリン1欠損による成長ホルモン分泌不全症モデルマウスの作製2008
- Author(s)
  中島光業、渡辺苑、加来鉄平、古川美子
- Organizer
  日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド
- Data Source
  KAKENHI-PROJECT-20591104
[Presentation] 皮膚のバリア機能獲得とプレセニリン12007
- Author(s)
  中島光業, 古川美子
- Organizer
  第30回日本分子生物学会
- Place of Presentation
  横浜市
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591227
[Presentation] Accelerated acquisition of permeability barrier function in the skin of presenilin-l-deficient embryos.2007
- Author(s)
  Nakajima, M., Furukawa, Y.
- Organizer
  Biochemistry and Molecular Biology 2007
- Place of Presentation
  Yokohama
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591227
[Presentation] Presenilin-1 controls the growth and differentiation of endothelial progenitor cells through its b-catenin-binding region.2006
- Author(s)
  Nakajima, M., Furukawa, Y.
- Organizer
  Annual meeting of the Pharmaceutical Society of Japan, Chuugoku-ShikokuBranch Office
- Place of Presentation
  Hiroshima
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591227
[Presentation] プレセニリン1による血管内皮前駆細胞の増殖分化制御2006
- Author(s)
  中島光業, 古川美子
- Organizer
  第45回日本薬学会・日本病院薬剤師会中国四国支部学術大会
- Place of Presentation
  広島市
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591227
[Presentation] Wnt1-cre, Wnt1-GAL4ダブルトランスジェニックマウスで認められる精神疾患様行動異常と聴覚過敏
- Author(s)
  中島光業、西川知沙、宮坂勇輝、吉川欣亮、森久倫、鶴田桃子、奥山聡、古川美子
- Organizer
  日本神経科学会
- Place of Presentation
  横浜
- Year and Date
  2014-09-11 – 2014-09-13
- Data Source
  KAKENHI-PROJECT-25461567

1. OKUYAMA Satoshi (40550380)

# of Collaborated Projects: 9 results

# of Collaborated Products: 53 results
2. FURUKAWA Yoshiko (20219108)

# of Collaborated Projects: 6 results

# of Collaborated Products: 48 results
3. AMAKURA Yoshiaki (50321857)

# of Collaborated Projects: 2 results

# of Collaborated Products: 19 results
4. 加来鉄平 (20435077)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
5. 並河徹 (50180534)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
6. 澤本篤志 (70760388)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
7. YOSHIDA Takashi (20025696)

# of Collaborated Projects: 1 results

# of Collaborated Products: 12 results
8. YOSHIMURA Morio (80454891)

# of Collaborated Projects: 1 results

# of Collaborated Products: 16 results
9. FURUKAWA Shoei (90159129)

# of Collaborated Projects: 1 results

# of Collaborated Products: 26 results
10. FUKUMITSU Hidemitsu (00308280)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 畑晶之 (50241972)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 岩村樹憲 (70184900)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 波多江典之 (30449912)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 中西雅之 (00281048)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 大原浩貴 (10609225)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 吉川欣亮

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

NAKAJIMA Mitsunari 中島 光業

中島 光業 ナカジマ ミツナリ

Research Projects

Research Products

Co-Researchers

ダブルコンジェニックSHRSP/Izmを用いた河内晩柑果皮の脳血管障害防御機構の解析

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

健康寿命延伸物質の探索 ～ドラッグリポジショニングの活用～Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Protection mechanism of citrus components against brain dysfunction using double congenic SHRSP/Izm

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

A proposed novel method for screening caloric restriction mimetics and its applicationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The effects of citrus-related compounds on global cerebral ischemic injury in SHRSP.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Phenotypes Associated with Psychiatric Disorders are Sex-Specific in a Mutant Mouse LinePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

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Analysis of a mouse model showing autism-related behavioral abnormalitiesPrincipal Investigator

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Effect of citrus components on the injured spinal cord

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Restricted growth and insulin-like growth factor-1 deficiency in mice lacking presenilin-1 in the neural crest cell lineagePrincipal Investigator

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脊髄損傷修復への応用をめざした新たな神経保護薬の創生

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A causative gene for early-onset familial Alzheimer's disease, presenilin 1, and skull vault formationPrincipal Investigator

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A causative gene for early-onset familial Alzheimer's disease, presenilin 1, and cardiac morphogenesisPrincipal Investigator

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[Journal Article] Sulconazole induces pyroptosis promoted by interferon-γ in monocyte/macrophage lineage cells2024

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NAKAJIMA Mitsunari 中島光業

中島光業ナカジマミツナリ

健康寿命延伸物質の探索　～ドラッグリポジショニングの活用～Principal Investigator