HIASA Yoichi 日浅陽一

… Alternative Names

日浅陽一ビアサヨウイチ

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Researcher Number	70314961
Other IDs	https://orcid.org/0000-0003-4117-339X
Affiliation (Current)	2024: 愛媛大学, 医学系研究科, 教授
Affiliation (based on the past Project Information) *help	2024: 愛媛大学, 医学系研究科, 教授 2016 – 2022: 愛媛大学, 医学系研究科, 教授 2012 – 2015: 愛媛大学, 医学(系)研究科(研究院), 教授 2010 – 2011: 愛媛大学, 大学院・医学系研究科, 准教授 2005 – 2009: 愛媛大学, 医学部附属病院, 講師 2003 – 2004: 愛媛大学, 医学部附属病院, 助手 2000: 愛媛大学, 医学部・附属病院, 助手
Review Section/Research Field	Principal Investigator Gastroenterology / Basic Section 53010:Gastroenterology-related / Gastroenterology Except Principal Investigator Gastroenterology / Epidemiology and preventive medicine
Keywords	Principal Investigator PKR / C型肝炎ウイルス / PERK / 肝細胞癌 / hepatocellular carcinoma / eIF2-alpha / Protein kinase R / MAPK / ERストレス / c-Fos … More / c-Jun / 細胞増殖 / アポトーシス / 複製モデル / リバビリン / インターフェロン / Interleukin-8 / eIF2-γ / eIF2-β / eIF2-α / protein kinase R / eIF2B / eIF2-gamma / eIF2-beta / 肝癌 / 慢性肝障害 / MAPKシグナル / Protein kinase R (PKR) / cleaved カスパーゼ3 / Bcl-2 / long noncoding RNA / RMRP / 肝細胞がん / JNK1 / DNAメチル化 / hepatitis C virus / AP-1 / eIF2alpha / PKR-like ER kinase / DNMT / Hepatocellular carcinoma / anti-HCV therapy / T cell / Ribavirin / Interferon / HCV replication model / Hepatitis C virus / EVR / 抗HCV治療 / 持続感染 / T細胞 / IL-8 / MAP kinase / Erk / リン酸化c-Fos / リン酸化c-Jun / JNK / 細胞接着因子 / HCV粒子生成可能複製系 / Annexin V / H77 / PCRアレイ / siRNA / Caspase / interleukin-8 / WT1遺伝子 / 2'5'-OAS / 末梢血T細胞 / 末梢血リンパ球 / MxA / 内因性IFN-β / リバビリン末梢血リンパ球 / インターフェロン誘導遺伝子 / phosphorylated PKR / real-time RT-PCR / RPA / アデノウイルスベクター / T7ポリメラーゼ / 樹状細胞 / HCV … More Except Principal Investigator Dendritic cell / Vaccine / Hepatitis B Virus / 樹状細胞 / ワクチン / B型肝炎 / 睡眠時間 / 発がん / 肝細胞ガン / 睡眠時無呼吸症候群 / 肝細胞癌 / 睡眠呼吸障害 / 肝疾患 Less

Role of endoplasmic reticulum stress response proteins, PERK and eIF2, in hepatocarcinogenesis progression.Principal Investigator
- Principal Investigator
  
  日浅陽一
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Ehime University
Potential for targeted therapy of eIF2, a PKR-related molecule involved in carcinogenesis and progression of hepatocellular carcinoma.Principal Investigator
- Principal Investigator
  
  日浅陽一
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Ehime University
The role of ER stress and PERK for chronic liver injury and hepatocarcinogenesisPrincipal Investigator
- Principal Investigator
  
  Hiasa Yoichi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Ehime University
The role of protein kinase R (PKR) for hepatocarcinogenesis and progression of hepatocellular carcinoma during inflammation due to hepatitis C virus infection.Principal Investigator
- Principal Investigator
  
  Hiasa Yoichi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Ehime University
The association between sleep-disordered breathing and prognosis among patients with liver diseases:
- Principal Investigator
  
  Furukawa Shinya
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Epidemiology and preventive medicine
- Research Institution
  Ehime University
The role of PKR and its modification to the function of host cell in hepatocellular carcinomaPrincipal Investigator
- Principal Investigator
  
  HIASA Yoichi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Ehime University
Investigation about the role of WT1 and PKR for the carcinogenesis or progression of hepatocellular carcinomaPrincipal Investigator
- Principal Investigator
  
  HIASA Yoichi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Ehime University
Research about the key molecule to contribute for hepatitis C virus elimination from the aspect of liver host cell and immune cellsPrincipal Investigator
- Principal Investigator
  
  HIASA Yoichi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Ehime University
Identification of the key molecules for hepatitis C virus (HCV) replication and the translation research for the noble protocols against HCV using cell-based HCV replication model.Principal Investigator
- Principal Investigator
  
  HIASA Yoichi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Ehime University
C型肝炎ウイルス(HCV)複製モデルを用いたHCV増殖に伴う肝発癌機序の解明Principal Investigator
- Principal Investigator
  
  日浅陽一
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Ehime University
Study about mechanism of action of vaccine therapy and their antiviral potential: development of more potent and new regimen of vaccine therapy
- Principal Investigator
  
  ONJI Morikazu
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Ehime University
C型肝炎ウィルス遺伝子発現によって生じる抗原提示樹状細胞の機能異常が発生する機序Principal Investigator
- Principal Investigator
  
  日浅陽一
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Gastroenterology
- Research Institution
  Ehime University

[Book] 第31回犬山シンポジウム -B型肝炎・C型肝炎・肝癌2018
- Author(s)
  渡辺崇夫、徳本良雄、日浅陽一
- Total Pages
  4
- Publisher
  犬山シンポジウム記録刊行会
- Data Source
  KAKENHI-PROJECT-15K09006
[Book] 消化器疾患のための栄養療法の手引き2018
- Author(s)
  仙波英徳、日浅陽一
- Total Pages
  3
- Publisher
  日本消化器病学会
- Data Source
  KAKENHI-PROJECT-15K09006
[Book] 消化器疾患　最新の治療　2017-20182017
- Author(s)
  阿部雅則、日浅陽一
- Total Pages
  4
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-15K09006
[Book] 肝疾患治療マニュアル2017
- Author(s)
  徳本良雄、日浅陽一
- Total Pages
  9
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-15K09006
[Book] 1336専門家による私の治療 2017-18年度版2017
- Author(s)
  徳本良雄、日浅陽一
- Total Pages
  2
- Publisher
  日本医事新報社
- ISBN
  9784784946501
- Data Source
  KAKENHI-PROJECT-15K09006
[Book] 消化器疾患　最新の治療2017-20182017
- Author(s)
  阿部雅則、日浅陽一
- Total Pages
  4
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-15K09006
[Book] 今日の治療指針2017年度版2017
- Author(s)
  日浅陽一
- Total Pages
  2
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-15K09006
[Book] 臨牀消化器内科　10月号2016
- Author(s)
  徳本良雄、日浅陽一
- Total Pages
  9
- Publisher
  日本メディカルセンター
- Data Source
  KAKENHI-PROJECT-15K09006
[Book] Modern Physician 11月号2016
- Author(s)
  吉田理、三宅映己、日浅陽一
- Total Pages
  6
- Publisher
  株式会社　新興医学出版社
- Data Source
  KAKENHI-PROJECT-15K09006
[Book] 肝臓クリニカルアップデート vol. 22016
- Author(s)
  渡辺崇夫、日浅陽一
- Total Pages
  5
- Publisher
  医学図書出版株式会社
- Data Source
  KAKENHI-PROJECT-15K09006
[Book] 新薬展望2014「消化器疾患治療薬」2013
- Author(s)
  廣岡昌史、池田宜央、日浅陽一
- Total Pages
  7
- Publisher
  医薬ジャーナル社
- Data Source
  KAKENHI-PROJECT-24590980
[Book] Bio Clinica 「7 DAAによる治療困難例への挑戦、肝移植例　他」2013
- Author(s)
  徳本良雄、日浅陽一
- Total Pages
  6
- Publisher
  北隆館
- Data Source
  KAKENHI-PROJECT-24590980
[Book] Dendritic Cells in Autoimmune Liver Diseases.2012
- Author(s)
  Abe M, Hiasa Y, Onji M
- Total Pages
  5
- Publisher
  Curr Immunol Rev
- Data Source
  KAKENHI-PROJECT-24590980
[Book] Dendritic Cell-Based Immune Therapy in Liver Diseases.2012
- Author(s)
  Akbar SMF, Hiasa Y, Mahtab MAI, Onji M
- Total Pages
  9
- Publisher
  Curr Immunol Rev
- Data Source
  KAKENHI-PROJECT-24590980
[Book] 愛媛大学における急性肝炎症例の解析わが国における急性肝炎の現状　全国調査2008-20112012
- Author(s)
  徳本良雄、渡辺崇夫、多田藤政、上杉和寛、眞柴寿枝、重松秀一郎、阿部雅則、日浅陽一、恩地森一
- Total Pages
  11
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-24590980
[Book] 動物モデルによるHBV増殖とその応用B型肝炎ウイルス研究の進歩2011
- Author(s)
  日浅陽一、恩地森一
- Publisher
  日本臨床社
- Data Source
  KAKENHI-PROJECT-21590848
[Book] 新時代のウイルス性肝炎学III B型肝炎3)動物モデルによるHBV増殖とその応用2011
- Author(s)
  日浅陽一、恩地森一
- Publisher
  日本臨牀社
- Data Source
  KAKENHI-PROJECT-21590848
[Book] クリニカルトピックスWilms' tumor 1遺伝子と肝細胞癌2010
- Author(s)
  日浅陽一、上杉和寛、恩地森一
- Publisher
  BIO Clinica
- Data Source
  KAKENHI-PROJECT-21590848
[Book] インターフェロンを中心に合併症のある症例自己免疫性肝疾患. そこが知りたいC型肝炎のベスト治療2009
- Author(s)
  日浅陽一、恩地森一
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-19590771
[Book] HBc抗原特異的細胞傷害性T細胞を誘導しうるHBc抗原ワクチン療法の開発. 第10回学術集会記録集2008
- Author(s)
  日浅陽一
- Publisher
  Liver Forum in Kyoto
- Data Source
  KAKENHI-PROJECT-19590771
[Book] 合併症のある症例自己免疫性肝疾患そこが知りたい C型肝炎のベスト治療インターフェロンを中心に2008
- Author(s)
  日浅陽一, 恩地森一(分担執筆)
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-19590771
[Book] 消化器疾患ガイドライン-最新の診療指針-2006
- Author(s)
  日浅陽一, 恩地森一
- Publisher
  総合医学社
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590650
[Book] 消化器疾患ガイドライン -最新の診療指針-2006
- Author(s)
  日浅陽一, 恩地森一
- Publisher
  総合医学社
- Data Source
  KAKENHI-PROJECT-17590650
[Book] 肝臓フォーラム '04記録集 T7ポリメラーゼによるHCV長期発現モデルの作成と抗ウイルス薬の評価2005
- Author(s)
  日浅陽一
- Publisher
  医事出版社
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590650
[Book] 肝臓フォーラム ‘04記録集 T7ポリメラーゼによるHCV長期発現モデルの作成と抗ウイルス薬の評価2005
- Author(s)
  日浅陽一
- Publisher
  医事出版社
- Data Source
  KAKENHI-PROJECT-17590650
[Book] A型肝炎の重症化、劇症化とその機序ウイルス性肝炎(下)2004
- Author(s)
  日浅陽一, 恩地森一
- Total Pages
  5
- Publisher
  日本臨床社
- Data Source
  KAKENHI-PROJECT-15790350
[Journal Article] Glasgow prognostic score predicts survival in patients with unresectable hepatocellular carcinoma treated with lenvatinib: a multicenter analysis2022
- Author(s)
  Tada Toshifumi、Kumada Takashi、Hiraoka Atsushi、Hiasa Yoichi、et al.
- Journal Title
  
  European Journal of Gastroenterology and Hepatology
  
  Volume: 34 Issue: 8 Pages: 857-864
- DOI
  10.1097/meg.0000000000002398
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08008
[Journal Article] Atezolizumab plus bevacizumab versus lenvatinib for unresectable hepatocellular carcinoma: a large real-life worldwide population.2022
- Author(s)
  Casadei-Gardini A, Rimini M, Tada T, Suda G, Shimose S, Kudo M, Cheon J, Finkelmeier F, Lim HY, Rimassa L, Presa J, Masi G, Yoo C, Lonardi S, Tovoli F, Kumada T, Sakamoto N, Iwamoto H, Aoki T, Chon HJ, Himmelsbach V, Pressiani T, Montes M, Vivaldi C, Solda C, Piscaglia F, Hiraoka A, Nishida N, et al.
- Journal Title
  
  European journal of cancer
  
  Volume: 180 Pages: 9-20
- DOI
  10.1016/j.ejca.2022.11.017
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07184, KAKENHI-PROJECT-21K07950, KAKENHI-PROJECT-21K08008, KAKENHI-PROJECT-22K08046
[Journal Article] Early experience of atezolizumab plus bevacizumab treatment for unresectable hepatocellular carcinoma BCLC‐B stage patients classified as beyond up to seven criteria ? Multicenter analysis2022
- Author(s)
  Hiraoka A、Kumada T、Tada T、Hirooka M、Kariyama K、Tani J、Atsukawa M、Takaguchi K、Itobayashi E、Fukunishi S、Tsuji K、Ishikawa T、Tajiri K、Ochi H、Yasuda S、Toyoda H、Ogawa C、Nishimura T、Hatanaka T、Kakizaki S、Shimada N、Kawata K、Naganuma A、Tanaka T、Ohama H、Nouso K、Morishita A、Hiasa Y、Kudo M、et al.
- Journal Title
  
  Hepatology Research
  
  Volume: 52 Issue: 3 Pages: 308-316
- DOI
  10.1111/hepr.13734
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08008
[Journal Article] Comparative efficacy and safety of atezolizumab and bevacizumab between hepatocellular carcinoma patients with viral and non‐viral infection: A Japanese multicenter observational study2022
- Author(s)
  Hatanaka Takeshi、Kakizaki Satoru、Hiraoka Atsushi、Hiasa Yoichi、et al.
- Journal Title
  
  Cancer Medicine
  
  Volume: 12 Issue: 5 Pages: 5293-5303
- DOI
  10.1002/cam4.5337
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08008
[Journal Article] C-reactive protein to albumin ratio predicts survival in patients with unresectable hepatocellular carcinoma treated with lenvatinib2022
- Author(s)
  Tada Toshifumi、Kumada Takashi、Hiraoka Atsushi、Hiasa Yoichi、et al.
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 8421-8421
- DOI
  10.1038/s41598-022-12058-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08008
[Journal Article] Identification of microRNA-96-5p as a postoperative, prognostic microRNA predictor in non-viral hepatocellular carcinoma2022
- Author(s)
  Matsui T, Hamada TS, Naito Y, Nojima M, Iio E, Tamori A, Kubo S, Ide T, Kondo Y, Eguchi Y, Komori A, Morine Y, Shimada M, Utsunomiya T, Kimura K, Hiasa Y, Ochiya T, Naiki A, Takahashi S, Tanaka Y
- Journal Title
  
  Hepatol Res.
  
  Volume: 52(1) Issue: 1 Pages: 93-104
- DOI
  10.1111/hepr.13674
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08374, KAKENHI-PROJECT-19K07486, KAKENHI-PROJECT-21K07990, KAKENHI-PROJECT-21K08008
[Journal Article] Clinical Usefulness of Surgical Resection Including the Complementary Use of Radiofrequency Ablation for Intermediate-Stage Hepatocellular Carcinoma2022
- Author(s)
  Ohama Hideko、Hiraoka Atsushi、Tada Fujimasa、Hiasa Yoichi、et al.
- Journal Title
  
  Cancers
  
  Volume: 15 Issue: 1 Pages: 236-236
- DOI
  10.3390/cancers15010236
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08008
[Journal Article] Prognostic impact of C-reactive protein and alpha-fetoprotein in immunotherapy score in hepatocellular carcinoma patients treated with atezolizumab plus bevacizumab: a multicenter retrospective study2022
- Author(s)
  Hatanaka Takeshi、Kakizaki Satoru、Hiraoka Atsushi、Hiasa Yoichi、et al.
- Journal Title
  
  Hepatology International
  
  Volume: 16 Issue: 5 Pages: 1150-1160
- DOI
  10.1007/s12072-022-10358-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08008
[Journal Article] Atezolizumab plus bevacizumab treatment for unresectable hepatocellular carcinoma: Early clinical experience2022
- Author(s)
  Hiraoka A、Kumada T、Tada T、Hirooka M、Kariyama K、Tani J、Atsukawa M、Takaguchi K、Itobayashi E、Fukunishi S、Tsuji K、Ishikawa T、Tajiri K、Ochi H、Yasuda S、Toyoda H、Ogawa C、Nishimura T、Hatanaka T、Ohama H、Nouso K、Morishita A、Tsutsui A、Nagano T、Itokawa N、Hiasa Y、Kudo M、et al.
- Journal Title
  
  Cancer Reports
  
  Volume: 5 Issue: 2
- DOI
  10.1002/cnr2.1464
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08008
[Journal Article] Neutrophil-lymphocyte ratio predicts early outcomes in patients with unresectable hepatocellular carcinoma treated with atezolizumab plus bevacizumab: a multicenter analysis2022
- Author(s)
  Tada Toshifumi、Kumada Takashi、Hiraoka Atsushi、Hiasa Yoichi、et al.
- Journal Title
  
  European Journal of Gastroenterology and Hepatology
  
  Volume: 34 Issue: 6 Pages: 698-706
- DOI
  10.1097/meg.0000000000002356
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08008
[Journal Article] Does first‐line treatment have prognostic impact for unresectable HCC? -Atezolizumab plus bevacizumab versus lenvatinib2022
- Author(s)
  Hiraoka Atsushi、Kumada Takashi、Tada Toshifumi、Hiasa Yoichi、et al.
- Journal Title
  
  Cancer Medicine
  
  Volume: 12 Issue: 1 Pages: 325-334
- DOI
  10.1002/cam4.4854
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08008
[Journal Article] The hepatocellular carcinoma modified Gustave Roussy Immune score (HCC-GRIm score) as a novel prognostic score for patients treated with atezolizumab and bevacizumab: A multicenter retrospective analysis2022
- Author(s)
  Hatanaka Takeshi、Naganuma Atsushi、Hiraoka Atsushi、Hiasa Yoichi、et al.
- Journal Title
  
  Cancer Medicine
  
  Volume: 12 Issue: 4 Pages: 4259-4269
- DOI
  10.1002/cam4.5294
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08008
[Journal Article] Therapeutic efficacy of atezolizumab plus bevacizumab treatment for unresectable hepatocellular carcinoma in patients with Child‐Pugh class A or B liver function in real‐world clinical practice2022
- Author(s)
  Tanaka Takaaki、Hiraoka Atsushi、Tada Toshifumi、Hiasa Yoichi、et al.
- Journal Title
  
  Hepatology Research
  
  Volume: 52 Issue: 9 Pages: 773-783
- DOI
  10.1111/hepr.13797
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08008
[Journal Article] A Novel SAVE Score to Stratify Decompensation Risk in Compensated Advanced Chronic Liver Disease (CHESS2102): An International Multicenter Cohort Study2022
- Author(s)
  Liu Chuan、Cao Zhujun、Yan Huadong、Hiasa Yoichi、et al.
- Journal Title
  
  American Journal of Gastroenterology
  
  Volume: 117 Issue: 10 Pages: 1605-1613
- DOI
  10.14309/ajg.0000000000001873
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08008
[Journal Article] New prognostic system based on inflammation and liver function predicts prognosis in patients with advanced unresectable hepatocellular carcinoma treated with atezolizumab plus bevacizumab: A validation study2022
- Author(s)
  Tada Toshifumi、Kumada Takashi、Hiraoka Atsushi、Hiasa Yoichi、et al.
- Journal Title
  
  Cancer Medicine
  
  Volume: 12 Issue: 6 Pages: 6980-6993
- DOI
  10.1002/cam4.5495
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08008
[Journal Article] Clinical Predictor of Urinary Protein as Adverse Event Associated with Atezolizumab plus Bevacizumab Treatment for Unresectable Hepatocellular Carcinoma2022
- Author(s)
  Hiraoka Atsushi、Kumada Takashi、Tada Toshifumi、Hiasa Yoichi、et al.
- Journal Title
  
  Oncology
  
  Volume: 100 Issue: 12 Pages: 645-654
- DOI
  10.1159/000526521
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08008
[Journal Article] Development and validation of a modified albumin?bilirubin grade and α-fetoprotein score (mALF score) for hepatocellular carcinoma patients receiving atezolizumab and bevacizumab2022
- Author(s)
  Hatanaka Takeshi、Kakizaki Satoru、Hiraoka Atsushi、Hiasa Yoichi、et al.
- Journal Title
  
  Hepatology International
  
  Volume: 17 Issue: 1 Pages: 86-96
- DOI
  10.1007/s12072-022-10406-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08008
[Journal Article] Association of early bevacizumab interruption with efficacy of atezolizumab plus bevacizumab for advanced hepatocellular carcinoma: A landmark analysis2022
- Author(s)
  Hatanaka Takeshi、Hiraoka Atsushi、Tada Toshifumi、Hiasa Yoichi、et al.
- Journal Title
  
  Hepatology Research
  
  Volume: 52 Issue: 5 Pages: 462-470
- DOI
  10.1111/hepr.13748
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08008
[Journal Article] Comparison of Surgical Resection and Percutaneous Ultrasonographic Guided Radiofrequency Ablation for Initial Recurrence of Hepatocellular Carcinoma in Early Stage following Curative Treatment2022
- Author(s)
  Ohama Hideko、Hiraoka Atsushi、Tada Fujimasa、Hiasa Yoichi、et al.
- Journal Title
  
  Cancers
  
  Volume: 14 Issue: 22 Pages: 5524-5524
- DOI
  10.3390/cancers14225524
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08008
[Journal Article] Nutritional Status Is Associated with Prognosis in Patients with Advanced Unresectable Hepatocellular Carcinoma Treated with Atezolizumab plus Bevacizumab2022
- Author(s)
  Tada Toshifumi、Kumada Takashi、Hiraoka Atsushi、Hiasa Yoichi、et al.
- Journal Title
  
  Oncology
  
  Volume: 101 Issue: 4 Pages: 270-282
- DOI
  10.1159/000527676
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08008
[Journal Article] Safety and efficacy of atezolizumab plus bevacizumab in elderly patients with hepatocellular carcinoma: A multicenter analysis2022
- Author(s)
  Tada Toshifumi、Kumada Takashi、Hiraoka Atsushi、Hiasa Yoichi、et al.
- Journal Title
  
  Cancer Medicine
  
  Volume: 11 Issue: 20 Pages: 3796-3808
- DOI
  10.1002/cam4.4763
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08008
[Journal Article] Efficacy of lenvatinib for unresectable hepatocellular carcinoma based on background liver disease etiology: multi-center retrospective study2021
- Author(s)
  Hiraoka A、Kumada T、Tada T、Tani J、Kariyama K、Fukunishi S、Atsukawa M、Hirooka M、Tsuji K、Ishikawa T、Takaguchi K、Itobayashi E、Tajiri K、Shimada N、Shibata H、Ochi H、Kawata K、Yasuda S、Toyoda H、Aoki T、Tanaka T、Ohama H、Hiasa Y、Kudo M、et al.
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 16663-16663
- DOI
  10.1038/s41598-021-96089-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08008
[Journal Article] Lenvatinib versus Sorafenib as first‐line treatment in hepatocellular carcinoma: A multi‐institutional matched case‐control study2021
- Author(s)
  Rimini M、Shimose S、Lonardi S、Tada T、Masi G、Iwamoto H、Lai E、Burgio V、Hiraoka A、Ishikawa T、Solda C、Shirono T、Vivaldi C、Takaguchi K、Shimada N、Astara G、Koga H、Nouso K、Joko K、Torimura T、Hiasa Y、Salani F、Scartozzi M、Cascinu S、Casadei GA.
- Journal Title
  
  Hepatology Research
  
  Volume: 51 Issue: 12 Pages: 1229-1241
- DOI
  10.1111/hepr.13718
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08008
[Journal Article] Adverse events as potential predictive factors of activity in patients with advanced hepatocellular carcinoma treated with lenvatinib2021
- Author(s)
  Rapposelli IG、Tada T、Shimose S、Burgio V、Kumada T、Iwamoto H、Hiraoka A、Niizeki T、Atsukawa M、Koga H、Hirooka M、Torimura T、Iavarone M、Tortora R、Campani C、Lonardi S、Tamburini E、Piscaglia F、Masi G、Cabibbo G、Giuseppe FF、Silletta M、Tsuji K、Ishikawa T、Hiasa Y、Casadei GA、et al.
- Journal Title
  
  Liver International
  
  Volume: 41 Issue: 12 Pages: 2997-3008
- DOI
  10.1111/liv.15014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08008
[Journal Article] Radiofrequency Ablation Covering the Entire Tumor Blood Drainage Area Improves Survival in Hepatocellular Carcinoma2021
- Author(s)
  Hirooka M、Koizumi Y、Tanaka T、Sunago K、Nakamura Y、Watanabe T、Yoshida O、Tokumoto Y、Abe M、Hiasa Y.
- Journal Title
  
  Hepatology Communications
  
  Volume: 5 Issue: 7 Pages: 1300-1309
- DOI
  10.1002/hep4.1703
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08008
[Journal Article] Impact of Early Lenvatinib Administration on Survival in Patients with Intermediate-Stage Hepatocellular Carcinoma: A Multicenter, Inverse Probability Weighting Analysis2021
- Author(s)
  Tada T、Kumada T、Hiraoka A、Michitaka K、Atsukawa M、Hirooka M、Tsuji K、Ishikawa T、Takaguchi K、Kariyama K、Itobayashi E、Tajiri K、Shimada N、Shibata H、Ochi H、Yasuda S、Toyoda H、Fukunishi S、Ohama H、Kawata K、Nakamura S、Nouso K、Tsutsui A、Nagano T、Hiasa Y、et al.
- Journal Title
  
  Oncology
  
  Volume: 99 Issue: 8 Pages: 518-527
- DOI
  10.1159/000515896
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08008
[Journal Article] The long noncoding RNA of RMRP is downregulated by PERK, which induces apoptosis in hepatocellular carcinoma cells2021
- Author(s)
  Yukimoto Atsushi、Watanabe Takao、Sunago Kotaro、Nakamura Yoshiko、Tanaka Takaaki、Koizumi Yohei、Yoshida Osamu、Tokumoto Yoshio、Hirooka Masashi、Abe Masanori、Hiasa Yoichi
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 7926-7926
- DOI
  10.1038/s41598-021-86592-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08007, KAKENHI-PROJECT-20K08388, KAKENHI-PROJECT-21K08008
[Journal Article] AFP and eGFR are related to early and late recurrence of HCC following antiviral therapy.2021
- Author(s)
  Watanabe T, Tokumoto Y, Joko K, Michitaka K, Horiike N, Tanaka Y, Tada F, Kisaka Y, Nakanishi S, Yamauchi K, Ochi H, Hiraoka A, Yagi S, Yukimoto A, Hirooka M, Abe M, Hiasa Y
- Journal Title
  
  BMC Cancer
  
  Volume: 14;21(1) Issue: 1 Pages: 699-699
- DOI
  10.1186/s12885-021-08401-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08388, KAKENHI-PROJECT-21K08008
[Journal Article] Impact of modified albumin?bilirubin grade on survival in patients with HCC who received lenvatinib2021
- Author(s)
  Tada T、Kumada T、Hiraoka A、Atsukawa M、Hirooka M、Tsuji K、Ishikawa T、Takaguchi K、Kariyama K、Itobayashi E、Tajiri K、Shimada N、Shibata H、Ochi H、Yasuda S、Toyoda H、Fukunishi S、Ohama H、Kawata K、Tani J、Nakamura S、Nouso K、Tsutsui A、Nagano T、Takaaki T、Hiasa Y、et al.
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 14474-14474
- DOI
  10.1038/s41598-021-93794-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08008
[Journal Article] Development of a method for measuring spleen stiffness by transient elastography using a new device and ultrasound-fusion method2021
- Author(s)
  Tanaka Takaaki、Hirooka Masashi、Koizumi Yohei、Watanabe Takao、Yoshida Osamu、Tokumoto Yoshio、Nakamura Yoshiko、Sunago Koutarou、Yukimoto Atsushi、Abe Masanori、Hiasa Yoichi
- Journal Title
  
  PLOS ONE
  
  Volume: 16 Issue: 2 Pages: e0246315-e0246315
- DOI
  10.1371/journal.pone.0246315
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07634, KAKENHI-PROJECT-18K08007
[Journal Article] Therapeutic efficacy of lenvatinib as third‐line treatment after regorafenib for unresectable hepatocellular carcinoma progression2021
- Author(s)
  Hiraoka A、Kumada T、Hatanaka T、Tada T、Kariyama K、Tani J、Fukunishi S、Atsukawa M、Hirooka M、Tsuji K、Ishikawa T、Takaguchi K、Itobayashi E、Tajiri K、Shimada N、Shibata H、Ochi H、Kawata K、Yasuda S、Toyoda H、Ogawa C、Tamai T、Kakizaki S、Tojima H、Hiasa Y、Kudo M、et al.
- Journal Title
  
  Hepatology Research
  
  Volume: 51 Issue: 8 Pages: 880-889
- DOI
  10.1111/hepr.13644
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08008
[Journal Article] Safety and efficacy of lenvatinib in elderly patients with unresectable hepatocellular carcinoma: A multicenter analysis with propensity score matching.2020
- Author(s)
  Tada T, Kumada T, Hiraoka A, Michitaka K, Atsukawa M, Hirooka M, Tsuji K, Ishikawa T, Takaguchi K, Kariyama K, Itobayashi E, Tajiri K, Shimada N, Shibata H, Ochi H, Toyoda H, Nouso K, Tsutsui A, Nagano T, Itokawa N, Hayama K, Imai M, Joko K, Koizumi Y, Hiasa Y.
- Journal Title
  
  Hepatol Res.
  
  Volume: 50 Issue: 1 Pages: 75-83
- DOI
  10.1111/hepr.13427
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08007
[Journal Article] Treatment on the spleen prevents the progression of secondary sarcopenia in patients with liver cirrhosis2020
- Author(s)
  Hirooka M, Koizumi Y, Tanaka T, Nakamura Y, Sunago K, Yukimoto A, Watanabe T, Yoshida O, Miyake T, Tokumoto Y, Matsuura B, Abe M, Hiasa Y
- Journal Title
  
  Hepatol Commun
  
  Volume: 4 Issue: 12 Pages: 1812-1823
- DOI
  10.1002/hep4.1604
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08333, KAKENHI-PROJECT-18K07634, KAKENHI-PROJECT-18K08007
[Journal Article] Post-Progression Treatment Eligibility of Unresectable Hepatocellular Carcinoma Patients Treated with Lenvatinib.2020
- Author(s)
  Hiraoka A, Kumada T, Fukunishi S, Atsukawa M, Hirooka M, Tsuji K, Ishikawa T, Takaguchi K, Kariyama K, Itobayashi E, Tajiri K, Shimada N, Shibata H, Ochi H, Tada T, Toyoda H, Yokohama K, Nouso K, Tsutsui A, Nagano T, Itokawa N, Hayama K, Arai T, Imai M, Joko K, Koizumi Y, Hiasa Y, Michitaka K, Kudo M.
- Journal Title
  
  Liver Cancer
  
  Volume: 9 Issue: 1 Pages: 73-83
- DOI
  10.1159/000503031
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08007
[Journal Article] Zinc deficiency as an independent prognostic factor for patients with early hepatocellular carcinoma due to hepatitis virus.2020
- Author(s)
  Hiraoka A, Nagamatsu K, Izumoto H, Adachi T, Yoshino T, Tsuruta M, Aibiki T, Okudaira T, Yamago H, Iwasaki R, Suga Y, Mori K, Miyata H, Tsubouchi E, Ninomiya T, Kawasaki H, Hirooka M, Matsuura B, Abe M, Hiasa Y, Michitaka K.
- Journal Title
  
  Hepatol Res.
  
  Volume: 50 Issue: 1 Pages: 92-100
- DOI
  10.1111/hepr.13430
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08007
[Journal Article] Therapeutic Effects of the PKR Inhibitor C16 Suppressing Tumor Proliferation and Angiogenesis in Hepatocellular Carcinoma in Vitro and in Vivo.2020
- Author(s)
  Watanabe T, Ninomiya H, Saitou T, Takanezawa S, Yamamoto S, Imai Y, Yoshida O, Kawakami R, Hirooka M, Abe M, Imamura T, Hiasa Y.
- Journal Title
  
  Scientific Reports
  
  Volume: 20;10(1) Issue: 1 Pages: 5133-5133
- DOI
  10.1038/s41598-020-61579-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K15818, KAKENHI-PROJECT-18K08007
[Journal Article] Advanced fibrosis of non-alcoholic steatohepatitis affects the significance of lipoprotein(a) as a cardiovascular risk factor2020
- Author(s)
  Konishi K, Miyake T, Furukawa S, Senba H, Kanzaki S, Nakaguchi H, Yukimoto A, Nakamura Y, Watanabe T, Koizumi Y, Yoshida O, Tokumoto Y, Hirooka M, Kumagi T, Abe M, Matsuura B, Hiasa Y.
- Journal Title
  
  Atherosclerosis
  
  Volume: 299 Pages: 32-37
- DOI
  10.1016/j.atherosclerosis.2020.02.026
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K11743, KAKENHI-PROJECT-18K15818, KAKENHI-PROJECT-18K07469, KAKENHI-PROJECT-20K08333, KAKENHI-PROJECT-20K08388, KAKENHI-PROJECT-18K07911, KAKENHI-PROJECT-18K08007
[Journal Article] Combination of Resection and Ablative Treatment for Hepatocellular Carcinoma: Usefulness of Complementary Radiofrequency Ablation.2019
- Author(s)
  Hiraoka A, Hirooka M, Ochi H, Koizumi Y, Izumoto H, Ueki H, Tsuruta M, Ono A, Yoshino T, Aibiki T, Okudaira T, Yamago H, Suga Y, Iwasaki R, Mori K, Miyata H, Kishida M, Tsubouchi E, Abe M, Matsuura B, Ninomiya T, Joko K, Kawasaki H, Hiasa Y, Michitaka K.
- Journal Title
  
  Oncology
  
  Volume: 96 Issue: 5 Pages: 242-251
- DOI
  10.1159/000496225
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08007
[Journal Article] Early Relative Change in Hepatic Function with Lenvatinib for Unresectable Hepatocellular Carcinoma2019
- Author(s)
  Ｈｉｒａｏｋａ　Ａｔｓｕｓｈｉ、Ｈｉｒｏｏｋａ　Ｍａｓａｓｈｉ、ｅｔ　ａｌ．
- Journal Title
  
  Oncology
  
  Volume: 97 Issue: 6 Pages: 334-340
- DOI
  10.1159/000502095
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07634, KAKENHI-PROJECT-18K08007
[Journal Article] Prognostic factor of lenvatinib for unresectable hepatocellular carcinoma in real‐world conditions?Multicenter analysis2019
- Author(s)
  Ｈｉｒａｏｋａ　Ａｔｓｕｓｈｉ、Ｈｉｒｏｏｋａ　Ｍａｓａｓｈｉ、ｅｔ　ａｌ．
- Journal Title
  
  Cancer Medicine
  
  Volume: 8 Issue: 8 Pages: 3719-3728
- DOI
  10.1002/cam4.2241
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07634, KAKENHI-PROJECT-18K08007
[Journal Article] Lenvatinib-induced thyroid abnormalities in unresectable hepatocellular carcinoma2019
- Author(s)
  Koizumi Yohei、Hirooka Masashi、Hiraoka Atsushi、Ochi Hironori、Tanaka Takaaki、Yukimoto Atsushi、Imai Yuusuke、Watanabe Takao、Yoshida Osamu、Miyake Teruki、Matsuura Bunzo、Michitaka Kojiro、Joko Kouji、Abe Masanori、Hiasa Yoichi
- Journal Title
  
  Endocr J
  
  Volume: 66 Issue: 9 Pages: 787-792
- DOI
  10.1507/endocrj.EJ19-0140
- NAID
  130007719421
- ISSN
  0918-8959, 1348-4540
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07634, KAKENHI-PROJECT-18K08007
[Journal Article] Clinical features of lenvatinib for unresectable hepatocellular carcinoma in real-world conditions: Multicenter analysis.2019
- Author(s)
  Hiraoka A, Kumada T, Kariyama K, Takaguchi K, Atsukawa M, Itobayashi E, Tsuji K, Tajiri K, Hirooka M, Shimada N, Shibata H, Ishikawa T, Ochi H, Tada T, Toyoda H, Nouso K, Tsutsui A, Itokawa N, Imai M, Joko K, Hiasa Y, Michitaka K.
- Journal Title
  
  Cancer Med.
  
  Volume: 8 Issue: 1 Pages: 137-146
- DOI
  10.1002/cam4.1909
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08007
[Journal Article] Important Clinical Factors in Sequential Therapy Including Lenvatinib against Unresectable Hepatocellular Carcinoma2019
- Author(s)
  Ｈｉｒａｏｋａ　Ａｔｓｕｓｈｉ、Ｈｉｒｏｏｋａ　Ｍａｓａｓｈｉ、ｅｔ　ａｌ．
- Journal Title
  
  Oncology
  
  Volume: 97 Issue: 5 Pages: 277-285
- DOI
  10.1159/000501281
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07634, KAKENHI-PROJECT-18K08007
[Journal Article] Stimulated hepatic stellate cell promotes progression of hepatocellular carcinoma due to protein kinase R activation2019
- Author(s)
  Imai Y, Yoshida O, Watanabe T, Yukimoto A, Koizumi Y, Ikeda Y, Tokumoto Y, Hirooka M, Abe M, Hiasa Y
- Journal Title
  
  PLos One
  
  Volume: 14 Issue: 2 Pages: e0212589-e0212589
- DOI
  10.1371/journal.pone.0212589
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07911, KAKENHI-PROJECT-18K08007, KAKENHI-PROJECT-18K15818, KAKENHI-PROJECT-17K15952
[Journal Article] Roles of protein kinase R in cancer: Potential as a therapeutic target.2018
- Author(s)
  Watanabe T, Imamura T, Hiasa Y.
- Journal Title
  
  Cancer Sci.
  
  Volume: 109 Issue: 4 Pages: 919-925
- DOI
  10.1111/cas.13551
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09006, KAKENHI-PROJECT-16K19349, KAKENHI-PROJECT-18K08007, KAKENHI-PROJECT-18K15818, KAKENHI-PLANNED-15H05952, KAKENHI-PROJECT-16H06280
[Journal Article] Impact of ALBI grade on survival in patients with HCC who received sorafenib: an analysis using time‐dependent ROC2018
- Author(s)
  Tada Toshifumi、Kumada Takashi、Toyoda Hidenori、Tsuji Kunihiko、Hiraoka Atsushi、Michitaka Kojiro、Deguchi Akihiro、Ishikawa Toru、Imai Michitaka、Ochi Hironori、Joko Koji、Shimada Noritomo、Tajiri Kazuto、Hirooka Masashi、Koizumi Yohei、Hiasa Yoichi、Tanaka Junko
- Journal Title
  
  Journal of Gastroenterology and Hepatology
  
  Volume: - Issue: 6 Pages: 1066-1073
- DOI
  10.1111/jgh.14564
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H03589, KAKENHI-PROJECT-18K08007
[Journal Article] Cigarette smoking is a risk factor for the onset of fatty liver disease in nondrinkers: A longitudinal cohort study.2018
- Author(s)
  Okamoto M, Miyake T, Kitai K, Furukawa S, Yamamoto S, Senba H, Kanzaki S, Deguchi A, Koizumi M, Ishihara T, Miyaoka H, Yoshida O, Hirooka M, Kumagi T, Abe M, Matsuura B, Hiasa Y.
- Journal Title
  
  PLoS One.
  
  Volume: 13 Issue: 4 Pages: e0195147-e0195147
- DOI
  10.1371/journal.pone.0195147
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09006
[Journal Article] Transcatheter Arterial Chemoembolization With or Without Radiofrequency Ablation: Outcomes in Patients With Barcelona Clinic Liver Cancer Stage B Hepatocellular Carcinoma.2018
- Author(s)
  Hirooka M, Hiraoka A, Ochi H, Kisaka Y, Joko K, Michitaka K, Hiasa Y.
- Journal Title
  
  AJR Am J Roentgenol.
  
  Volume: 210 Issue: 4 Pages: 891-898
- DOI
  10.2214/ajr.17.18177
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09006, KAKENHI-PROJECT-18K07634
[Journal Article] Genome-wide Association Study Identifies TLL1 Variant Associated With Development of Hepatocellular Carcinoma After Eradication of Hepatitis C Virus Infection.2017
- Author(s)
  Matsuura K, Honda M, et al.
- Journal Title
  
  Gastroenterology.
  
  Volume: - Issue: 6 Pages: 1383-1394
- DOI
  10.1053/j.gastro.2017.01.041
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04809, KAKENHI-PROJECT-16H05282, KAKENHI-PROJECT-16H05285, KAKENHI-PROJECT-15K15285, KAKENHI-PROJECT-16K15426, KAKENHI-PROJECT-15K08986, KAKENHI-PROJECT-15K09006, KAKENHI-PROJECT-15K09019, KAKENHI-PROJECT-16K09335, KAKENHI-PROJECT-17K09457, KAKENHI-PROJECT-15K08077, KAKENHI-PROJECT-15K08314
[Journal Article] Predictors of treatment efficacy and ALT non-normalization with sofosbuvir/ribavirin therapy for patients with hepatitis C virus genotype 2.2017
- Author(s)
  Watanabe T, Tokumoto Y, Joko K, Michitaka K, Horiike N, Tanaka Y, Tada F, Kisaka Y, Nakanishi S, Nonaka T, Yamauchi K, Hirooka M, Abe M, Hiasa Y.
- Journal Title
  
  J Med Virol.
  
  Volume: 89 Issue: 9 Pages: 1567-1573
- DOI
  10.1002/jmv.24776
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09006, KAKENHI-PROJECT-16K19349
[Journal Article] Downregulation of ANP32B exerts anti-apoptotic effects in hepatocellular carcinoma.2017
- Author(s)
  Ohno Y, Koizumi M, Nakayama H, Watanabe T, Hirooka M, Tokumoto Y, Kuroda T, Abe M, Fukuda S, Higashiyama S, Kumagi T, Hiasa Y.
- Journal Title
  
  PLoS One.
  
  Volume: 12 Issue: 5 Pages: 0177343-0177343
- DOI
  10.1371/journal.pone.0177343
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09006, KAKENHI-PROJECT-16K19349, KAKENHI-PROJECT-16K19350, KAKENHI-PROJECT-16K20013
[Journal Article] Antiemetic Effectiveness and Cost-Saving of Aprepitant plus Granisetron Is Superior to Palonosetron in Gastrointestinal Cancer Patients Who Received Moderately Emetogenic Chemotherapy.2017
- Author(s)
  Toda H, Kawazoe H, Yano A, Yamamoto Y, Watanabe Y, Yamamoto Y, Hiasa Y, Yakushijin Y, Tanaka A, Araki H.
- Journal Title
  
  J Cancer.
  
  Volume: 8 Issue: 8 Pages: 1371-1377
- DOI
  10.7150/jca.17102
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09006
[Journal Article] Role of hepatic resection in patients with intermediate-stage hepatocellular carcinoma: A multicenter study from Japan.2017
- Author(s)
  Tada T, Kumada T, Toyoda H, Tsuji K, Hiraoka A, Itobayashi E, Nouso K, Kariyama K, Ishikawa T, Hirooka M, Hiasa Y.
- Journal Title
  
  Cancer Sci.
  
  Volume: 108 Issue: 7 Pages: 1414-1420
- DOI
  10.1111/cas.13257
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25220206, KAKENHI-PROJECT-15K09006
[Journal Article] Quantitative assessment of liver fibrosis reveals a nonlinear association with fibrosis stage in nonalcoholic fatty liver disease.2017
- Author(s)
  Masugi Y, Abe T, Tsujikawa H, Effendi K, Hashiguchi A, Abe M, Imai Y, Hino K, Hige S, Kawanaka M, Yamada G, Kage M, Korenaga M, Hiasa Y, Mizokami M, Sakamoto M
- Journal Title
  
  Hepatol Commun
  
  Volume: 27 Issue: 1 Pages: 58-68
- DOI
  10.1002/hep4.1121
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09388, KAKENHI-PROJECT-26293179, KAKENHI-PROJECT-15K09006, KAKENHI-PROJECT-15K09007
[Journal Article] Upregulated absorption of dietary palmitic acids with changes in intestinal transporters in non-alcoholic steatohepatitis (NASH)2017
- Author(s)
  Utsunomiya H, Yamamoto Y, Takeshita E, Tokumoto Y, Tada F, Miyake T, Hirooka M, Abe M, Kumagi T, Matsuura B, Ikeda Y, Hiasa Y
- Journal Title
  
  J Gastroenterol
  
  Volume: 印刷中 Issue: 8 Pages: 940-954
- DOI
  10.1007/s00535-016-1298-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460939, KAKENHI-PROJECT-15K19335, KAKENHI-PROJECT-15K09008, KAKENHI-PROJECT-17K09350, KAKENHI-PROJECT-15K09006, KAKENHI-PROJECT-15K09007
[Journal Article] Nonalcoholic fatty liver with a hepatic arterial buffer response strongly associated with future metabolic disease.2017
- Author(s)
  Hirooka M, Koizumi Y, Miyake T, Watanabe T, Yoshida O, Tokumoto Y, Yukimoto A, Nakamura Y, Imai Y, Abe M, Hiasa Y.
- Journal Title
  
  Hepatol Commun.
  
  Volume: 1 Issue: 7 Pages: 623-633
- DOI
  10.1002/hep4.1070
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09006, KAKENHI-PROJECT-15K09007, KAKENHI-PROJECT-15K09960
[Journal Article] Differences in the risk of fatty liver for onset of impaired fasting glucose according to baseline plasma glucose levels2017
- Author(s)
  Miyake T, Hirooka M, Yoshida O, Furukawa S, Kumagi T, Koizumi M, Yamamoto S, Kuroda T, Arimitsu E, Takeshita E, Abe M, Kitai K, Matsuura B, Hiasa Y
- Journal Title
  
  J Gastroenterol
  
  Volume: 52 Issue: 2 Pages: 237-244
- DOI
  10.1007/s00535-016-1234-9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460939, KAKENHI-PROJECT-26461034, KAKENHI-PROJECT-15K09006, KAKENHI-PROJECT-15K09007, KAKENHI-PROJECT-15K00874, KAKENHI-PROJECT-16K19350
[Journal Article] Clinical utility of multipolar ablation with a 3-D simulator system for patients with liver cancer.2017
- Author(s)
  Hirooka M, Koizumi Y, Imai Y, Nakamura Y, Yukimoto A, Watanabe T, Yoshida O, Tokumoto Y, Abe M, Hiasa Y.
- Journal Title
  
  J Gastroenterol Hepatol.
  
  Volume: 32 Issue: 11 Pages: 1852-1858
- DOI
  10.1111/jgh.13772
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09006, KAKENHI-PROJECT-15K09960
[Journal Article] Simeprevir with peginterferon/ribavirin for patients with hepatitis C virus genotype 1: high frequency of viral relapse in elderly patients.2016
- Author(s)
  Watanabe T, Joko K, Hiasa Y, et al.
- Journal Title
  
  Springerplus
  
  Volume: 26 Issue: 1 Pages: 518-518
- DOI
  10.1186/s40064-016-2190-9
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K09006
[Journal Article] Characterization of Liver Monocytic Myeloid-Derived Suppressor Cells and Their Role in a Murine Model of Non-Alcoholic Fatty Liver Disease2016
- Author(s)
  Yao L, Abe M, Kawasaki K, Akbar SM, Matsuura B, Onji M, Hiasa Y.
- Journal Title
  
  PLoS One
  
  Volume: 11 Issue: 2 Pages: e0149948-e0149948
- DOI
  10.1371/journal.pone.0149948
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09006, KAKENHI-PROJECT-15K09007, KAKENHI-PROJECT-26460939
[Journal Article] Low alcohol consumption increases the risk of impaired glucose tolerance in patients with non-alcoholic fatty liver disease2016
- Author(s)
  Miyake T, Kumagi T, Hirooka M, Furukawa S, Yoshida O, Koizumi M, Yamamoto S, Watanabe T, Yamamoto Y, Tokumoto Y, Takeshita E, Abe M, Kitai K, Matsuura B, Hiasa Y.
- Journal Title
  
  Journal of Gastroenterology
  
  Volume: Epub ahead of print
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K09006
[Journal Article] Usefulness of a New Three-Dimensional Simulator System for Radiofrequency Ablation2016
- Author(s)
  Hirooka M, Koizumi Y, Imai Y, Miyake T, Watanabe T, Yoshida O, Takeshita E, Tokumoto Y, Abe M, Hiasa Y.
- Journal Title
  
  PLoS One
  
  Volume: 11 Issue: 2 Pages: e0148298-e0148298
- DOI
  10.1371/journal.pone.0148298
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K09006, KAKENHI-PROJECT-15K09960
[Journal Article] Low alcohol consumption increases the risk of impaired glucose tolerance in patients with non-alcoholic fatty liver disease.2016
- Author(s)
  Teruki Miyake
- Journal Title
  
  Journal of Gastroenterology
  
  Volume: 印刷中 Issue: 11 Pages: 1090-1100
- DOI
  10.1007/s00535-016-1194-0
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K00874, KAKENHI-PROJECT-26460939, KAKENHI-PROJECT-26461034, KAKENHI-PROJECT-15K09006, KAKENHI-PROJECT-15K09007
[Journal Article] Interleukin-34 as a fibroblast-derived marker of liver fibrosis in patients with non-alcoholic fatty liver disease.2016
- Author(s)
  Shoji H, Yoshio S, Mano Y, Kumagai E, Sugiyama M, Korenaga M, Arai T, Itokawa N, Atsukawa M, Aikata H, Hyogo H, Chayama K, Ohashi T, Ito K, Yoneda M, Nozaki Y, Kawaguchi T, Torimura T, Abe M, Hiasa Y, Kamiyama T, Fukai M, Taketomi A, Mizokami M, Kanto T*
- Journal Title
  
  Scientific Reports
  
  Volume: 6:28814 Issue: 1 Pages: 1-10
- DOI
  10.1038/srep28814
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461028, KAKENHI-PROJECT-15K09006, KAKENHI-PROJECT-15K09007, KAKENHI-PROJECT-16K09388
[Journal Article] Effects of long-term entecavir treatment on the incidence of hepatocellular carcinoma in chronic hepatitis B patients2016
- Author(s)
  Watanabe T, Tokumoto Y, Joko K, Michitaka K, Mashiba T, Hiraoka A, Ochi H, Koizumi Y, Tada F, Hirooka M, Yoshida O, Imai Y, Abe M, Hiasa Y.
- Journal Title
  
  Hepatology International
  
  Volume: 10 Issue: 2 Pages: 320-327
- DOI
  10.1007/s12072-015-9647-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09006
[Journal Article] Significance of exercise in nonalcoholic fatty liver disease in men: a community-based large cross-sectional study.2015
- Author(s)
  Miyake T, Kumagi T, Hirooka M, Furukawa S, Kawasaki K, Koizumi M, Todo Y, Yamamoto S, Nunoi H, Tokumoto Y, Ikeda Y, Abe M, Kitai K, Matsuura B, Hiasa Y.
- Journal Title
  
  J Gastroenterol
  
  Volume: 50 Issue: 2 Pages: 230-237
- DOI
  10.1007/s00535-014-0959-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24590980, KAKENHI-PROJECT-25750045, KAKENHI-PROJECT-26460768, KAKENHI-PROJECT-26461034, KAKENHI-PROJECT-15K19334
[Journal Article] Diminished immune response to vaccinations in a murine model of obesity: Role of myeloid-derived suppressor cells.2015
- Author(s)
  Chen S, Akbar SMF, Miyake T, Abe M, Al-Mahtab M, Furukawa S, Matsuura B, Hiasa Y, Onji M.
- Journal Title
  
  Obes Res Clin Pract
  
  Volume: 9 Issue: 1 Pages: 35-44
- DOI
  10.1016/j.orcp.2013.12.006
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24590979, KAKENHI-PROJECT-26460768, KAKENHI-PROJECT-26460939
[Journal Article] Nonalcoholic fatty liver disease: portal hypertension due to outflow block in patients without cirrhosis.2015
- Author(s)
  Hirooka M, Koizumi Y, Miyake T, Ochi H, Tokumoto Y, Tada F, Matsuura B, Abe M, Hiasa Y.
- Journal Title
  
  Radiology
  
  Volume: 274 Issue: 2 Pages: 597-604
- DOI
  10.1148/radiol.14132952
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590979, KAKENHI-PROJECT-24590980
[Journal Article] Characterization of the biliary tract by virtual ultrasonography constructed by gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid-enhanced magnetic resonance imaging2015
- Author(s)
  Koizumi Y, Hirooka M, Ochi H, Tokumoto Y, Takechi M, Hiraoka A, Ikeda Y, Kumagi T, Matsuura B, Abe M, Hiasa Y.
- Journal Title
  
  Journal of Medical Ultrasonics
  
  Volume: 42 Issue: 2 Pages: 185-193
- DOI
  10.1007/s10396-014-0598-9
- NAID
  130005465200
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09006, KAKENHI-PROJECT-15K09960
[Journal Article] Interleukin 28B polymorphism predicts interferon plus ribavirin treatment outcome in patients with hepatitis C virus-related liver cirrhosis: A multicenter retrospective study in Japan.2014
- Author(s)
  Shakado S, Sakisaka S, Okanoue T, Chayama K, Izumi N, Toyoda J, Tanaka E, Ido A, Takehara T, Yoshioka K, Hiasa Y, Nomura H, Seike M, Ueno Y, Kumada H.
- Journal Title
  
  Hepatol Res
  
  Volume: 44 Issue: 9 Pages: 983-992
- DOI
  10.1111/hepr.12280
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24590980, KAKENHI-PROJECT-25670369, KAKENHI-PROJECT-26670383
[Journal Article] Short sleep duration reduces the risk of nonalcoholic fatty liver disease onset in men: a community-based longitudinal cohort study.2014
- Author(s)
  Miyake T, Kumagi T, Furukawa S, Hirooka M, Kawasaki K, Koizumi M, Todo Y, Yamamoto S, Tokumoto Y, Ikeda Y, Abe M, Kitai K, Matsuura B, Hiasa Y.
- Journal Title
  
  J Gastroenterol
  
  Volume: Epub Issue: 5 Pages: 583-9
- DOI
  10.1007/s00535-014-0989-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24590980, KAKENHI-PROJECT-26460768, KAKENHI-PROJECT-26461034
[Journal Article] 18F-FDG-PET/CT predicts the distribution of microsatellite lesions in hepatocellular carcinoma.2014
- Author(s)
  Ochi H, Hirooka M, Hiraoka A, Koizumi Y, Abe M, Sogabe I, Ishimaru Y, Furuya K, Miyagawa M, Kawasaki H, Michitaka K, Takada Y, Mochizuki T, Hiasa Y.
- Journal Title
  
  Mol Clin Oncol
  
  Volume: 2 Issue: 5 Pages: 798-804
- DOI
  10.3892/mco.2014.328
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24590980
[Journal Article] Hyperuricemia is a risk factor for the onset of impaired fasting glucose in men with a high plasma glucose level: a community-based study.2014
- Author(s)
  Miyake T, Kumagi T, Furukawa S, Hirooka M, Kawasaki K, Koizumi M, Todo Y, Yamamoto S, Abe M, Kitai K, Matsuura B, Hiasa Y.
- Journal Title
  
  PLoS ONE
  
  Volume: 9 Issue: 9 Pages: e107882-e107882
- DOI
  10.1371/journal.pone.0107882
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24590979, KAKENHI-PROJECT-24590980
[Journal Article] New susceptibility and resistance HLA-DP alleles to HBV-related diseases identified by a trans-ethnic association study in Asia.2014
- Author(s)
  Nishida N, Sawai H, Kashiwase K, Minami M, Sugiyama M, Seto WK, Yuen MF, Posuwan N, Poovorawan Y, Ahn SH, Han KH, Matsuura K, Tanaka Y, Kurosaki M, Asahina Y, Izumi N, Kang JK, （省略）, Tokunaga K, and Mizokami M
- Journal Title
  
  PLoS One
  
  Volume: 9 Issue: 2 Pages: e86449-e86449
- DOI
  10.1371/journal.pone.0086449
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22133008, KAKENHI-PROJECT-23390117, KAKENHI-PROJECT-23390201, KAKENHI-PROJECT-23590985, KAKENHI-PROJECT-24390187, KAKENHI-PROJECT-24590960, KAKENHI-PROJECT-24590980, KAKENHI-PROJECT-24790728, KAKENHI-PROJECT-25293169, KAKENHI-PROJECT-25461010, KAKENHI-PROJECT-25670366, KAKENHI-PROJECT-25860574, KAKENHI-PROJECT-25870178, KAKENHI-PROJECT-26461027, KAKENHI-PROJECT-26670378, KAKENHI-PROJECT-25291103
[Journal Article] Pancreatic congestion in liver cirrhosis correlates with impaired insulin secretion.2014
- Author(s)
  Kuroda T, Hirooka M, Koizumi M, Ochi H, Hisano Y, Bando K, Matsuura B, Kumagi T, Hiasa Y.
- Journal Title
  
  J Gastroenterol
  
  Volume: Epub Issue: 6 Pages: 583-9
- DOI
  10.1007/s00535-014-1001-8
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24590980, KAKENHI-PROJECT-26460939, KAKENHI-PROJECT-26461034, KAKENHI-PROJECT-15K19334
[Journal Article] Maximum standardized uptake value in 18F-fluoro-2-deoxyglucose positron emission tomography is associated with advanced tumor factors in esophageal cancer.2014
- Author(s)
  Kajiwara T, Hiasa Y, Nishina T, Matsumoto T, Hori S, Nadano S, Iguchi H, Takeji S, Tsubouchi E, Ikeda Y, Onji M.
- Journal Title
  
  Mol Clin Oncol
  
  Volume: 2 Issue: 2 Pages: 313-321
- DOI
  10.3892/mco.2014.238
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24590980
[Journal Article] Wilms' tumor 1 gene modulates Fas-related death signals and anti-apoptotic functions in hepatocellular carcinoma.2013
- Author(s)
  Uesugi K, Hiasa Y, Tokumoto Y, Mashiba T, Koizumi Y, Hirooka M, Abe M, Matsuura B, Onji M.
- Journal Title
  
  J Gastroenterol.
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590980
[Journal Article] FGF3/FGF4 amplification and multiple lung metastases in responders to sorafenib in hepatocellular carcinoma.2013
- Author(s)
  Arao T, Ueshima K, Matsumoto K, Nagai T, Kimura H, Hagiwara S, Sakurai T, Haji S, Kanazawa A, Hidaka H, Iso Y, Kubota K, Shimada M, Utsunomiya T, Hirooka M, Hiasa Y, Toyoki Y, Hakamada K, Yasui K, Kumada T, Toyoda H, Sato S, Hisai H, Kuzuya T, Tsuchiya K, Izumi N, Arii S, Nishio K, Kudo M.
- Journal Title
  
  Hepatology
  
  Volume: 57 Issue: 4 Pages: 1407-1415
- DOI
  10.1002/hep.25956
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590470, KAKENHI-PROJECT-23590998, KAKENHI-PROJECT-23701089, KAKENHI-PROJECT-23790820, KAKENHI-PROJECT-24590980, KAKENHI-PROJECT-24591990, KAKENHI-PROJECT-24592003
[Journal Article] Des-gamma-carboxy prothrombin identified by P-11 and P-16 antibodies reflects prognosis for patients with hepatocellular carcinoma.2013
- Author(s)
  Takeji S, Hirooka M, Koizumi Y, Tokumoto Y, Abe M, Ikeda Y, Nadano S, Hiasa Y, Onji M.
- Journal Title
  
  J Gastroenterol Hepatol
  
  Volume: 28 Issue: 4 Pages: 671-7
- DOI
  10.1111/jgh.12076
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590980
[Journal Article] Increased B cell-activating factor promotes tumor invasion and metastasis in human pancreatic cancer.2013
- Author(s)
  Koizumi M, Hiasa Y, Kumagi T, Yamanishi H, Azemoto N, Kobata T, Matsuura B, Abe M, Onji M.
- Journal Title
  
  PLoS One
  
  Volume: 8 Issue: 8 Pages: e71367-e71367
- DOI
  10.1371/journal.pone.0071367
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591014, KAKENHI-PROJECT-24590980
[Journal Article] Blockade of B-cell-activating factor signaling enhances hepatic steatosis induced by a high-fat diet and improves insulin sensitivity.2013
- Author(s)
  Kasawaki K, Abe M, Tada F, Tokumoto Y, Chen S, Miyake T, Furukawa S, Matsuura B, Hiasa Y, Onji M.
- Journal Title
  
  Laboratory Investigation
  
  Volume: 93 Issue: 3 Pages: 311-321
- DOI
  10.1038/labinvest.2012.176
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590979, KAKENHI-PROJECT-24590980
[Journal Article] Inhibition of hepatocellular carcinoma by PegIFNα2a in patients with chronic hepatitis C: a nationwide multi-center cooperative study.2013
- Author(s)
  Izumi N, Asahina Y, Kumada H et al
- Journal Title
  
  J Gastroenterol
  
  Volume: 48 Issue: 3 Pages: 382-390
- DOI
  10.1007/s00535-012-0641-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590831, KAKENHI-PROJECT-24590960, KAKENHI-PROJECT-24590980, KAKENHI-PROJECT-24659368, KAKENHI-PROJECT-24890058, KAKENHI-PROJECT-25293169, KAKENHI-PROJECT-25670366
[Journal Article] Protein kinase R modulates c-Fos and c-Jun signaling to promote proliferation of hepatocellular carcinoma with hepatitis C virus infection.2013
- Author(s)
  Watanabe T, Hiasa Y, Tokumoto Y, Hirooka M, Abe M, Ikeda Y, Matsuura B, Chung RT, Onji M.
- Journal Title
  
  PLoS One
  
  Volume: 8 Issue: 7 Pages: e67750-e67750
- DOI
  10.1371/journal.pone.0067750
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590980
[Journal Article] B cell activating factor in obesity is regulated by oxidative stress in adipocytes2013
- Author(s)
  Tada F, Abe M, Kawasaki K, Miyake T, Shiyi C, Hiasa Y, Matsuura B, Onji M.
- Journal Title
  
  Journal of Clinical Biochemistry and Nutrition
  
  Volume: 52 Issue: 2 Pages: 120-127
- DOI
  10.3164/jcbn.12-115
- NAID
  130004466705
- ISSN
  0912-0009, 1880-5086
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590980
[Journal Article] Oral administration of carbonic anhydrase I ameliorates murine experimental colitis induced by Foxp3-CD4+CD25- T cells.2013
- Author(s)
  Mori K, Yamanishi H, Ikeda Y, Kumagi T, Hiasa Y, Matsuura B, Abe M, Onji M.
- Journal Title
  
  J Leukoc Biol
  
  Volume: 93 Issue: 6 Pages: 963-972
- DOI
  10.1189/jlb.1212612
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591014, KAKENHI-PROJECT-24590980
[Journal Article] Wilms' tumor 1 gene modulates Fas-related death signals and anti-apoptotic functions in hepatocellular carcinoma.2013
- Author(s)
  Uesugi K, Hiasa Y, Tokumoto Y, Mashiba T, Koizumi Y, Hirooka M, Abe M, Matsuura B, Onji M.
- Journal Title
  
  J Gastroenterol
  
  Volume: 48 Issue: 9 Pages: 1069-80
- DOI
  10.1007/s00535-012-0708-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590980
[Journal Article] Importance of screening for synchronous malignant neoplasms in patients with hepatocellular carcinoma: impact of FDG PET/CT.2013
- Author(s)
  Hiraoka A, Hirooka M, Ochi H, Koizumi Y, Shimizu Y, Shiraishi A, Yamago H, Tanihira T, Miyata H, Ninomiya T, Kawasaki H, Ishimaru Y, Sogabe I, Inoue T, Abe M, Hiasa Y, Matsuura B, Onji M, Michitaka K.
- Journal Title
  
  Liver Int.
  
  Volume: 33 Issue: 7 Pages: 1085-91
- DOI
  10.1111/liv.12161
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590980
[Journal Article] Lymphotoxin β Receptor Signaling Promotes Development of Autoimmune Pancreatitis.2012
- Author(s)
  Seleznik GM, Reding T, Romrig F,…… Kumagi T, et al.
- Journal Title
  
  Gastroenterology
  
  Volume: 143 Issue: 5 Pages: 1361-1374
- DOI
  10.1053/j.gastro.2012.07.112
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591014, KAKENHI-PROJECT-24590980
[Journal Article] Phase I/II study of immunotherapy using tumor antigen-pulsed dendritic cells in patients with hepatocellular carcinoma.2012
- Author(s)
  Tada F, Abe M, Hirooka M, Ikeda Y, Hiasa Y, Lee Y, Jung NC, Lee WB, Lee HS, Bae YS, Onji M.
- Journal Title
  
  Int J Oncol.
  
  Volume: 41 Issue: 5 Pages: 1601-1609
- DOI
  10.3892/ijo.2012.1626
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590980
[Journal Article] High Serum Palmitic Acid is Associated with Low Antiviral Effects of Interferon-Based Therapy for Hepatitis C Virus.2012
- Author(s)
  Miyake T, Hiasa Y, Hirooka M, Tokumoto Y, Watanabe T, Furukawa S, Ueda T, Yamamoto S, Kumagi T, Miyaoka H, Abe M, Matsuura B, Onji M.
- Journal Title
  
  Lipids
  
  Volume: 47 Issue: 11 Pages: 1053-1062
- DOI
  10.1007/s11745-012-3716-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591014, KAKENHI-PROJECT-23700907, KAKENHI-PROJECT-24590980
[Journal Article] Ribavirin regulates hepatitis C virus replication through enhancing interferon-stimulated genes and interleukin 82012
- Author(s)
  Tokumoto Y, Hiasa Y, Uesugi K, 他7名、2番目
- Journal Title
  
  Journal of Infectious Diseases
  
  Volume: 205 Issue: 7 Pages: 1121-1130
- DOI
  10.1093/infdis/jis025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590848, KAKENHI-PROJECT-23591014, KAKENHI-PROJECT-24590980
[Journal Article] Rivabirin regulates hepatitis C virus replication through enhancing interferon-stimulated genes and interleukin 82012
- Author(s)
  Tokumoto Y, Hiasa Y, Uesugi K, 他7名
- Journal Title
  
  J Infect Dis
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590848
[Journal Article] Real-time tissue elastography for evaluation of hepatic fibrosis and portal hypertension in nonalcoholic fatty liver diseases.2012
- Author(s)
  Ochi H, Hirooka M, Koizumi Y, Miyake T, Tokumoto Y, Soga Y, Tada F, Abe M, Hiasa Y, Onji M.
- Journal Title
  
  Hepatology
  
  Volume: 56 Issue: 4 Pages: 1271-1278
- DOI
  10.1002/hep.25756
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590980
[Journal Article] Regulatory Dendritic Cells Pulsed with Carbonic Anhydrase I Protect Mice from Colitis Induced by CD4+CD25− T Cells.2012
- Author(s)
  Yamanishi H, Murakami H, Ikeda Y, Kumagi T, Hiasa Y, Abe M, Matsuura B, Onji M.
- Journal Title
  
  J Immunol
  
  Volume: 188 Issue: 5 Pages: 2164-2172
- DOI
  10.4049/jimmunol.1100559
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591014, KAKENHI-PROJECT-24590980
[Journal Article] Rapid alternative absorption of dietary long-chain fatty acids with upregulation of intestinal glycosylated CD36 in liver cirrhosis.2012
- Author(s)
  Yamamoto Y, Hiasa Y, Murakami H, Ikeda Y, Yamanishi H, Abe M, Matsuura B, Onji M.
- Journal Title
  
  Am J Clin Nutr.
  
  Volume: 96 Issue: 1 Pages: 90-101
- DOI
  10.3945/ajcn.111.033084
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590980
[Journal Article] Aerobic exercise improves insulin resistance and decreases body fat and serum levels of leptin in patients with hepatitis C virus2011
- Author(s)
  Konishi I, Hiasa Y, Tokumoto Y, 他5名
- Journal Title
  
  Hepatol Res
  
  Volume: 41巻 Pages: 928-935
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590848
[Journal Article] Factors predictive of sustained virological response following 72 weeks of combination therapy for genotype 1b hepatitis C2011
- Author(s)
  Chayama K, Hayes CN, Hiasa Y, 他14名
- Journal Title
  
  J Gastroenterol
  
  Volume: 46巻 Pages: 545-555
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590848
[Journal Article] Genome-wide association study identified ITPA/DDRGK1 variants reflecting thrombocytopenia in pegylated interferon and ribavirin therapy for chronic hepatitis C2011
- Author(s)
  Tanaka Y, Kurosaki M, Hiasa Y, 他19名
- Journal Title
  
  Hum Mol Genet
  
  Volume: 20巻 Pages: 3507-3516
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590848
[Journal Article] Splenic elasticity measured with real-time tissue elastography is a marker of portal hypertension2011
- Author(s)
  Hirooka M, Ochi H, Hiasa Y, 他6名
- Journal Title
  
  Radiology
  
  Volume: 261巻 Pages: 960-968
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590848
[Journal Article] Sustained virological response of patients with hepatitis C virus genotype 2 depends on pegylated interferon compliance2011
- Author(s)
  Watanabe T, Konishi I, Hiasa Y, 他12名
- Journal Title
  
  Hepatol Res
  
  Volume: 41巻 Pages: 720-730
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590848
[Journal Article] Hepatic elasticity in patients with ascites : evaluation with real-time tissue elastography2011
- Author(s)
  Hirooka M, Koizumi Y, Hiasa Y, 他4名, 3番目
- Journal Title
  
  AJR American Journal of Roentgenology
  
  Volume: 196 Issue: 6 Pages: W766-W771
- DOI
  10.2214/ajr.10.4867
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590848
[Journal Article] Liver Fibrosis in Patients with Chronic Hepatitis C : Noninvasive Diagnosis by Means of Real-time Tissue Elastography-Establishment of the Method for Measurement2011
- Author(s)
  Koizumi Y, Hirooka M, Hiasa Y, 他6名
- Journal Title
  
  Radiology
  
  Volume: 258巻 Pages: 610-617
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590848
[Journal Article] Hepatic elasticity in patients with ascites : evaluation with real-time tissue elastography2011
- Author(s)
  Hirooka M, Koizumi Y, Hiasa Y, 他4名
- Journal Title
  
  AJR Am J Roentgenol
  
  Volume: 196巻
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590848
[Journal Article] Association of IL28B variants with response to pegylated-interferon alpha plus ribavirin combination therapy reveals intersubgenotypic differences between genotypes 2a and 2b2011
- Author(s)
  Sakamoto N, Nakagawa M, Hiasa Y, 他17名
- Journal Title
  
  J Med Virol
  
  Volume: 83巻 Pages: 871-878
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590848
[Journal Article] Splenic elasticity measured with real-time tissue elastography is a marker of portal hypertension2011
- Author(s)
  Hirooka M, Ochi H, Hiasa Y, 他6名, 8番目
- Journal Title
  
  Radiology
  
  Volume: 261 Issue: 3 Pages: 960-968
- DOI
  10.1148/radiol.11110156
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590848
[Journal Article] Persistent expression of the full genome of hepatitis C virus in B cells induces spontaneous development of B-cell lymphomas in vivo2010
- Author(s)
  Kasama Y, Sekiguchi S, Hiasa Y, 他8名
- Journal Title
  
  Blood
  
  Volume: 116巻 Pages: 4926-4933
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590848
[Journal Article] Immune modulator and antiviral potential of dendritic cells pulsed with both hepatitis B surface antigen and core antigen for treating chronic HBV infection2010
- Author(s)
  Akbar SM, Yoshida O, Hiasa Y, 他5名
- Journal Title
  
  Antivir Ther
  
  Volume: 15巻 Pages: 887-895
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590848
[Journal Article] Accumulation of refractory factors for pegylated interferon plus ribavirin therapy in older female patients with chronic hepatitis C2010
- Author(s)
  Chayama K, Hayes CN, Hiasa Y, 他14名
- Journal Title
  
  Hepatol Res
  
  Volume: 40巻 Pages: 1155-1167
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590848
[Journal Article] Variability of the polymerase gene(NS5B) in HCV-infected women2010
- Author(s)
  Blackard JT, Ma G, Hiasa Y, 他8名
- Journal Title
  
  J Clin Microbiol
  
  Volume: 48巻 Pages: 4256-4259
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590848
[Journal Article] Liver Fibrosis in Patients with Chronic Hepatitis C : Noninvasive Diagnosis by Means of Real-time Tissue Elastography--Establishment of the Method for Measurement2010
- Author(s)
  Koizumi Y, Hirooka M, Hiasa Y, (他6名、8番目)
- Journal Title
  
  Radiology
  
  Volume: 258 Pages: 610-617
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590848
[Journal Article] Variability of the polymerase gene (NS5B) in hepatitis C virus-infected women2010
- Author(s)
  Blackard JT, Ma G, Hiasa Y, (他8名、7番目)
- Journal Title
  
  Journal of Clinical Microbiology
  
  Volume: 48 Pages: 4256-4259
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590848
[Journal Article] Mass reduction by radiofrequency ablation before hepatic arterial infusion chemotherapy improved prognosis for patients with huge hepatocellular carcinoma and portal vein thrombus2010
- Author(s)
  Hirooka M, Koizumi Y, Hiasa Y, 他5名
- Journal Title
  
  AJR Am J Roentgenol
  
  Volume: 194巻
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590848
[Journal Article] Impaired dendritic cell functions disrupt antigen-specific adaptive immune responses in mice with nonalcoholic fatty liver disease2010
- Author(s)
  Miyake T, Akbar SM, Hiasa Y, 他5名
- Journal Title
  
  J Gastroenterol
  
  Volume: 45巻 Pages: 859-867
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590848
[Journal Article] Safety and immunogenicity of hepatitis B surface antigen-pulsed dendritic cells in patients with chronic hepatitis B2010
- Author(s)
  Akbar SM, Furukawa S, Hiasa Y, 他3名
- Journal Title
  
  J Viral Hepat
  
  Volume: 18巻 Pages: 408-414
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590848
[Journal Article] Persistent expression of the full genome of hepatitis C virus in B cells induces spontaneous development of B-cell lymphomas in vivo2010
- Author(s)
  Kasama Y, Sekiguchi S, Hiasa Y, (他8名、9番目)
- Journal Title
  
  Blood
  
  Volume: 116 Pages: 4926-4933
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590848
[Journal Article] Mechanism of restoration of immune responses of patients with chronic hepatitis B during lamivudine therapy : increased antigen processing and presentation by dendritic cells2010
- Author(s)
  Akbar SM, Horiike N, Hiasa Y, 他5名
- Journal Title
  
  J Viral Hepat
  
  Volume: 18巻 Pages: 200-205
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590848
[Journal Article] Genome-wide association of IL28B with response to pegylated interferon-αand ribavirin therapy for chronic hepatitis C2009
- Author(s)
  Tanaka Y, Nishida N, Hiasa Y, 他26名
- Journal Title
  
  Nat Genet
  
  Volume: 48巻 Pages: 1647-1650
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590848
[Journal Article] Etiology of liver cirrhosis in Japan : a nationwide survey2009
- Author(s)
  Michitaka K, Nishiguchi S, Hiasa Y, 他3名
- Journal Title
  
  J Gastroenterol
  
  Volume: 45巻 Pages: 86-94
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590848
[Journal Article] Hepatocellular carcinoma for the non-specialist2009
- Author(s)
  Kumagi T, Hiasa Y, Hirschfield GM
- Journal Title
  
  BMJ
  
  Volume: 339巻 Pages: 1366-1370
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590848
[Journal Article] Diabetes pattern on the 75 g oral glucose tolerance test is a risk factor for hepatocellular carcinoma in patients with hepatitis C virus2009
- Author(s)
  Konishi I, Hiasa Y, Shigematsu S, 他7名
- Journal Title
  
  Liver Int
  
  Volume: 29巻 Pages: 1194-1201
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590848
[Journal Article] Diabetes pattern on the 75g oral glucose tolerance test is a risk factor for hepatocellular carcinoma in patients with hepatitis C virus2009
- Author(s)
  Konishi I, Hiasa Y, Shigematsu S, 他7名, 2番目
- Journal Title
  
  Liver International 29
  
  Pages: 1194-1201
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590848
[Journal Article] Genome-wide association of IL28B with response to pegylated interferon-α and ribavirin therapy for chronic hepatitis C2009
- Author(s)
  Tanaka Y, Nishida N, Hiasa Y, 他26名, 18番目
- Journal Title
  
  Nature Genetics 48
  
  Pages: 1647-1650
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590848
[Journal Article] Radiofrequency ablation therapy for hepatocellular carcinoma in elderly patients2009
- Author(s)
  Hiraoka A, Michitaka K, Hiasa Y, 他16名
- Journal Title
  
  J Gastroenterol Hepatol
  
  Volume: 25巻 Pages: 403-407
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590848
[Journal Article] Hepatocellular carcinoma for the non-specialist2009
- Author(s)
  Kumagi T, Hiasa Y, Hirschfield GM
- Journal Title
  
  BMJ 339
  
  Pages: 1366-1370
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590848
[Journal Article] Hepatitis C virus replication is inhibited by 22β-methoxyolean-12-ene-3β, 24(4β)-diol (ME3738) through enhancing IFN-β2008
- Author(s)
  Hiasa Y, Kuzuhara H, Tokumoto Y, (他6名, 1番目)
- Journal Title
  
  Hepatology 72
  
  Pages: 867-872
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590771
[Journal Article] Neuropsychiatric dysfunction in patients with chronic hepatitis and liver cirrhosis2008
- Author(s)
  Michitaka K, Tokumoto Y, Hiasa Y(他10名, 9番目)
- Journal Title
  
  Hepatology Research 38巻
  
  Pages: 1069-1075
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590771
[Journal Article] Protective role of interleukin-10-producing regulatory dendritic cells against murine autoimmune dendritic cells against murine autoimmune2008
- Author(s)
  Torisu M, Murakami H, Akbar F, Hiasa Y(他4名, 5番目)
- Journal Title
  
  Journal of Gastroenterology 43巻
  
  Pages: 100-107
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590771
[Journal Article] Impaired dendritic cell functions because of depletion of natural killer cells disrupt antigen-specific immune responses in mice2008
- Author(s)
  Yoshida O, Akbar F, Hiasa Y, (他4名, 6番目)
- Journal Title
  
  Clinical Experimental Immunology 152
  
  Pages: 174-181
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590771
[Journal Article] Liver/spleen volume ratio as a predictor of prognosis in primary biliary cirrhosis2008
- Author(s)
  Murata Y, Abe M, Hiasa Y(他7名, 3番目)
- Journal Title
  
  Journal of Gastroenterology 43巻
  
  Pages: 632-636
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590771
[Journal Article] Wilms' tumor 1 gene expression is increased in hepatocellular carcinoma and associated with poor prognosis2008
- Author(s)
  Sera T, Hiasa Y, Mashiba T(他7名, 2番目)
- Journal Title
  
  European Journal of Cancer 44巻
  
  Pages: 600-608
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590771
[Journal Article] Characteristic endoscopic features of portal hypertensive enteropathy2008
- Author(s)
  Higaki N, Matsui H, Hiasa Y(他5名, 6番目)
- Journal Title
  
  Journal of Gastroenterology 43巻
  
  Pages: 327-331
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590771
[Journal Article] Mutational analysis of predicted intracellular loop domains of human motilin receptor2008
- Author(s)
  Tokunaga H, Matsuura B, Hiasa Y(他5名, 7番目)
- Journal Title
  
  American Journal of Physiology Gastrointestinal and Liver Physiology 294巻
  
  Pages: 460-466
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590771
[Journal Article] Impaired dendritic cell functions because of depletion of natural killer cells disrupt antigen-specific immune responses in mice2008
- Author(s)
  Yoshida O, Akbar F, Hiasa Y(他4名, 6番目)
- Journal Title
  
  Clinical Experimental Immunology 152巻
  
  Pages: 174-181
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590771
[Journal Article] Efficacy of splenectomy for hypersplenic patients with advanced hepatocellular carcinoma2008
- Author(s)
  Hirooka M, Ishida K, Hiasa Y(他5名, 6番目)
- Journal Title
  
  Hepatology Research 38巻
  
  Pages: 1172-1177
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590771
[Journal Article] Wilms' tumour 1 gene expression is increased in hepatocellular carcinoma and associated with poor prognosis2008
- Author(s)
  Sera T, Hiasa Y, Mashiba T, Tokumoto Y, Hirooka M, et. al.
- Journal Title
  
  European Journal of Cancer 44
  
  Pages: 600-608
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590771
[Journal Article] Hepatitis C virus replication is inhibited by 22β-methoxyolean-12-ene -3β, 24(4β)-diol(ME3738) through enhancing IFN-β2008
- Author(s)
  Hiasa Y, Kuzuhara H, Tokumoto Y(他6名, 1番目)
- Journal Title
  
  Hepatology 72巻
  
  Pages: 867-872
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590771
[Journal Article] Mutational analysis of predicted intracellular loop domains of human motilin receptor2008
- Author(s)
  Tokunaga H, Matsuura B, Hiasa Y, (他5名, 7番目)
- Journal Title
  
  American Journal of Physiology Gastrointestinal and Liver Physiology 294
  
  Pages: 460-466
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590771
[Journal Article] Induction of anti-HBs in HB vaccine nonresponders in vivo by hepatitis B surface antigen-pulsed blood dendritic cells2007
- Author(s)
  Akbar SMF, Furukawa S, Hiasa Y(他3名, 4番目)
- Journal Title
  
  Journal of Hepatology 47巻
  
  Pages: 60-66
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590771
[Journal Article] Percutaneous ultrasound-guided radiofrequency ablation of hepatocellular carcinoma with artificially induced pleural effusion and ascites2007
- Author(s)
  Uehara T, Hirooka M, Hiasa Y(他5名, 3番目)
- Journal Title
  
  Journal of Gastroenterology 42巻
  
  Pages: 306-311
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590771
[Journal Article] Heterogeneity of hepatitis B virus genotype D in Japan2007
- Author(s)
  Michitaka K, Horiike N, Hiasa Y(他8名, 10番目)
- Journal Title
  
  Intervirology 50巻
  
  Pages: 150-155
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590771
[Journal Article] Hepatitis C virus expression and interferon antiviral action is dependent on PKR expression2007
- Author(s)
  Tokumoto Y, Hiasa Y, Horiike N, Michitaka K, et. al.
- Journal Title
  
  Journal of Medical Virology 79
  
  Pages: 1120-1127
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590771
[Journal Article] Engineering immune therapy against hepatitis B virus2007
- Author(s)
  Akbar F, Yoshida O, Hiasa Y(他2名, 4番目)
- Journal Title
  
  Hepatology Research 37巻
  
  Pages: 351-356
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590771
[Journal Article] Impaired dendritic cell function resulting from chronic undernutrition disrupts the antigen-specific immune response in mice2007
- Author(s)
  Niiya T, Akbar SMF, Hiasa Y(他6名, 8番目)
- Journal Title
  
  Journal of Nutrition 137巻
  
  Pages: 671-675
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590771
[Journal Article] Characteristics of geographic distributions and route of infection for hepatitis B virus genotype D in Ehime area in western Japan2007
- Author(s)
  Matsuura K, Michitaka K, Hiasa Y(他6名, 7番目)
- Journal Title
  
  Hepatology Research 37巻
  
  Pages: 255-262
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590771
[Journal Article] Characteristics of lamivudine-resistant hepatitis B virus(HBV) strains with and without breakthrough hepatitis in patients with chronic hepatitis B evaluated by serial HBV full-genome sequences2007
- Author(s)
  Horiike N, Duong TN, Hiasa Y(他5名, 5番目)
- Journal Title
  
  Journal of Medical Virology 79巻
  
  Pages: 911-918
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590771
[Journal Article] Diabetes mellitus reduces the therapeutic effectiveness of interferon-alpha2b plus ribavirin therapy in patients with chronic hepatitis C2007
- Author(s)
  Konishi I, Horiike N, Hiasa Y(他8名, 3番目)
- Journal Title
  
  Hepatology Research 37巻
  
  Pages: 331-336
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590771
[Journal Article] Identification of CIL epitopes in hepatitis C virus by a genome-wide computational scanning and a rational design of peptide vaccine.2007
- Author(s)
  Mashiba T, Udaka K, Hirachi Y, Hiasa Y, Miyakawa T, et al.
- Journal Title
  
  Immunogenetics 59
  
  Pages: 197-209
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590650
[Journal Article] Impaired dendritic cell function resulting from chronic undernutrition disrupts the antigen-specific immune response in mice.2007
- Author(s)
  Niiiya T, Akbar SM, Yoshida 0, Miyake T, Hiasa Y, Onji M, et a1.
- Journal Title
  
  Journal of Nutrition 137
  
  Pages: 671-675
- Data Source
  KAKENHI-PROJECT-17590650
[Journal Article] identification of CTL epitopes in hepatitis C virus by a genome-wide computational scanning and a rational design of peptide vaccine.2007
- Author(s)
  Mashiba T, Udaka K, Hirachi Y, Hiasa Y, Miyakawa T, et a1.
- Journal Title
  
  Immunogenetics 59
  
  Pages: 197-209
- Data Source
  KAKENHI-PROJECT-17590650
[Journal Article] Impaired dendritic cell function resulting from chronic undernutri t ion disrupts the antigen-specific immune response in mice.2007
- Author(s)
  Niiya T, Akbar SM, Yoshida 0, Miyake T, Matsuura B, Murakami H, Abe M, Hiasa Y, Onji M.
- Journal Title
  
  Journal of Nutrition 137
  
  Pages: 671-5
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590650
[Journal Article] Hepatitis C virus expression and interferon antiviral action is dependent on PKR expression2007
- Author(s)
  Tokumoto Y, Hiasa Y, Horiike N(他4名, 2番目)
- Journal Title
  
  Journal of Medical Virology 79巻
  
  Pages: 1120-1127
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590771
[Journal Article] Significance of laparoscopic splenectomy in patients with hypersplenism2007
- Author(s)
  Watanabe Y, Horiuchi A, Hiasa Y(他5名, 7番目)
- Journal Title
  
  World Journal of Surgery 31巻
  
  Pages: 549-555
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590771
[Journal Article] Prevalence of hepatitis E virus among wild boar in the Ehime area of western Japan2007
- Author(s)
  Michitaka K, Takahashi K, Hiasa Y(他6名, 5番目)
- Journal Title
  
  Hepatology Research 37巻
  
  Pages: 214-220
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590771
[Journal Article] Compartmentalization of hepatitis C virus (HCV) during HCV/HIV coinfection2007
- Author(s)
  Blackard JT, Hiasa Y, Smeaton L, Jamieson DJ, et. al.
- Journal Title
  
  Journal of Infectious Disease 195
  
  Pages: 1765-1773
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590771
[Journal Article] Heterogeneity of hepatitis B virus genotype D in Japan.2007
- Author(s)
  Michitaka K, Horiike N, Duong TN, Yagura M, Hiasa Y, Onji M, et al.
- Journal Title
  
  Intervirology 50
  
  Pages: 150-155
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590650
[Journal Article] Identification of CTL epitopes in hepatitis C virus by a genome-wide computational scanning and a rational design of peptide vaccine.2007
- Author(s)
  Mashiba T, Udaka K, Hirachi Y, Hiasa Y, Miyakawa T, Satta Y, Osoda T, Kataoka S, Kohara M, Onji M.
- Journal Title
  
  Immunogenetics 59
  
  Pages: 197-209
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590650
[Journal Article] Dietary habits and nutrient intake in non-alcoholic steatohepatitis.2007
- Author(s)
  Toshimitsu K, Matsuura B, Ohkubo I, Niiya T, Hiasa Y, Onji M, et al.
- Journal Title
  
  Nutrition 23
  
  Pages: 46-52
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590650
[Journal Article] Compartmentalization of hepatitis C virus(HCV) during HCV/HIV coinfection2007
- Author(s)
  Blackard JT, Hiasa Y, Smeaton L(他4名, 2番目)
- Journal Title
  
  Journal of Infectious Disease 195巻
  
  Pages: 1765-1773
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590771
[Journal Article] Recurrence of autoimmune hepatitis after liver transplantation without elevation of alanine aminotransferase2007
- Author(s)
  Yao H, Michitaka K, Hiasa Y(他6名, 7番目)
- Journal Title
  
  World Journal of Gastroenterology 13巻
  
  Pages: 1618-1621
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590771
[Journal Article] Impaired dendritic cell function resulting from chronic undernutrition disrupts the antigen-specific immune response in mice.2007
- Author(s)
  Niiya T, Akbar SM, Yoshida O, Miyake T, Hiasa Y, Onji M, et al.
- Journal Title
  
  Journal of Nutrition 137
  
  Pages: 671-675
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590650
[Journal Article] Dietary habits and nutrient intake in non-alcoholic steatohepatitis.2007
- Author(s)
  Toshimitsu K, Matsuura B, Ohkubo I, Niiya T, Furukawa S, Hiasa Y, Kawamura M, Ebihara K, Onji M.
- Journal Title
  
  Nutrition 23
  
  Pages: 46-52
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590650
[Journal Article] Identification of CTL epitopes in hepatitis C virus by a genome-wide computational scanning and a rational design of peptide vaccine2007
- Author(s)
  Mashiba T, Udaka K, Hiasa Y(他7名, 4番目)
- Journal Title
  
  Immunogenetics 59巻
  
  Pages: 197-209
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590771
[Journal Article] Dietary habits and nutrient intake in non-alcoholic steatohepatitis2007
- Author(s)
  Toshimitsu K, Matsuura B, Hiasa Y(他6名, 6番目)
- Journal Title
  
  Nutrition 23巻
  
  Pages: 46-52
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590771
[Journal Article] Heterogeneity of hepatitis B virus genotype D in Japan.2007
- Author(s)
  Michitaka K, Horiike N, Duong TN, Yagura M, Harada H, Shibayama T, Inui A, Fujisawa T, Matsuura K, Hiasa Y, Onji M.
- Journal Title
  
  Intervirology 50
  
  Pages: 150-5
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590650
[Journal Article] Cell-based models of sustained, interferon-sensitive hepatitis C virus genotype 1 replication.2006
- Author(s)
  Hiasa Y, Blackard JT, Lin W, Kamegaya Y, et al.
- Journal Title
  
  Journal of Virological Methods 132
  
  Pages: 195-203
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590650
[Journal Article] Tracing the history of hepatitis B virus genotype D in western Japan.2006
- Author(s)
  Michitaka K, Tanaka Y, Horiike N, Duong TN, Chen Y, Matsuura K, Hiasa Y, Mizokami M, Onji M.
- Journal Title
  
  Journal of Medical Virology 78
  
  Pages: 44-52
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590650
[Journal Article] Prognosis following transcatheter arterial embolization for 121 patients with unresectable hepatocellular carcinoma with or without a history of treatment.2006
- Author(s)
  Hiraoka A, Kumagi T, Hirooka M, Uehara T, Hiasa Y, Onji M, et al.
- Journal Title
  
  World Journal of Gastroenterology 12
  
  Pages: 2075-2079
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590650
[Journal Article] Prognosis following transcatheter arterial embolization for 121 patients with unresectable hepatocellular carcinoma with or without a history of treatment.2006
- Author(s)
  Hiraoka A, Kumagi T, Hirooka M, Uehara T, Kurose K, Iuchi H, Hiasa Y, Matsuura B, Michitaka K, Kumano S, Tanaka H, Yamashita Y, Horiike N, Mochizuki T, Onji M.
- Journal Title
  
  World Journal of Gastroenterology 12
  
  Pages: 2075-9
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590650
[Journal Article] Understanding the precise function of interferon regulatory factor 3 in hepatitis C virus replication will lead to a new strategy for therapy.2006
- Author(s)
  Hiasa Y, Onji M
- Journal Title
  
  Journal of Gastroenterology 41
  
  Pages: 814-815
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590650
[Journal Article] Clinical features of symptomatic primary biliary cirrhosis initially complicated with esophageal varices.2006
- Author(s)
  Murata Y, Abe M, Furukawa S, Kumagi T, Matsui H, Matsuura B, Hiasa Y, Onji M.
- Journal Title
  
  Journal of Gastroenterology 41
  
  Pages: 1220-6
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590650
[Journal Article] Tracing the history of hepatitis B virus genotype D in western Japan.2006
- Author(s)
  Michitaka K, Tanaka Y, Horiike N, Duong TN, Hiasa Y, et al.
- Journal Title
  
  Journal of Medical Virology 78
  
  Pages: 44-52
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590650
[Journal Article] Clinical features of symptomatic primary biliary cirrhosis initially complicated with esophageal varices.2006
- Author(s)
  Murata Y, Abe M, Furukawa S, Kumagi T, Matsui H, Hiasa Y, Onji M, et al.
- Journal Title
  
  Journal of Gastroenterology 41
  
  Pages: 1220-1226
- Data Source
  KAKENHI-PROJECT-17590650
[Journal Article] Cell-based models of sustained, interferon-sensitive hepatitis C virus genotype 1 replication.2006
- Author(s)
  Hiasa Y, Blackard JT, Lin W, Kamegaya Y, Horiike N, Onji M, Schmidt EV, Chung RT.
- Journal Title
  
  Journal of Virological Methods 132
  
  Pages: 195-203
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590650
[Journal Article] Clinical features of symptomatic primary biliary cirrhosis initially complicated with esophageal varices.2006
- Author(s)
  Murata Y, Abe M, Furukawa S, Kumagi T, Hiasa Y, Onji M, et al.
- Journal Title
  
  Journal of Gastroenterology 41
  
  Pages: 1220-1226
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590650
[Journal Article] Understanding the precise function of interferon regulatory factor 3 in hepatitis C virus replication will lead to a new strategy for therapy.2006
- Author(s)
  Hiasa Y, Onji M.
- Journal Title
  
  Journal of Gastroenterology 41
  
  Pages: 814-5
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590650
[Journal Article] In vivo immunization by vaccine therapy following virus suppression by lamivudine : a novel approach for treating patients with chronic hepatitis B.2005
- Author(s)
  Horiike N, Akbar SMF, Michitaka K, Joukou K, Yamamoto K, Kojima N, Hiasa Y, Abe M, Onji M.
- Journal Title
  
  Journal of Clinical Virology 32
  
  Pages: 156-161
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590650
[Journal Article] In vivo immunization by vaccine therapy following virus suppression by lamivudine : a novel approach for treating patients with chronic hepatitis B.2005
- Author(s)
  Horiike N, Akbar SMF, Michitaka K, Joukou K, Yamamoto K, Hiasa Y, et al.
- Journal Title
  
  Journal of Clinical Virology 32
  
  Pages: 156-161
- Data Source
  KAKENHI-PROJECT-15790350
[Journal Article] Detection of hepatitis C virus (HCV) in serum and peripheral-blood mononuclear cells from HCV-monoinfected and HIV/HCV-coinfected persons.2005
- Author(s)
  Blackard JT, Smeaton L, Hiasa Y, Horiike N, Onji M, et al.
- Journal Title
  
  Journal of Infectious Diseases 192
  
  Pages: 258-265
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590650
[Journal Article] Detection of hepatitis C virus (HCV) in serum and peripheral-blood mononuclear cells from HCV-monoinfected and HIV/HCV-coinfected persons.2005
- Author(s)
  Blackard JT, Smeaton L, Hiasa Y, Horiike N, Onji M, Jamieson DJ, Rodriguez I, Mayer KH, Chung RT.
- Journal Title
  
  Journal of Infectious Diseases 192
  
  Pages: 258-265
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590650
[Journal Article] Hepatitis C virus acts as a tumor accelerator by blocking apoptosis in a mouse model of hepatocarcinogenesis.2005
- Author(s)
  Kamegaya Y, Hiasa Y, Zukerberg L, Fowler N, Blackard JT, Lin W, et al.
- Journal Title
  
  Hepatology 41
  
  Pages: 660-667
- Data Source
  KAKENHI-PROJECT-15790350
[Journal Article] Hepatitis C virus expression suppresses interferon signaling by degrading STAT1.2005
- Author(s)
  Lin W, Choe WH, HIasa Y, Kamegaya Y, Blackaro JT, Schmidt EV, Chung RT.
- Journal Title
  
  Gastroenterology 128
  
  Pages: 1034-1041
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590650
[Journal Article] Co-infection with hepatitis B virus genotype D and other genotypes in Western Japan.2005
- Author(s)
  Michitaka K, Horiike N, Chen Y, Duong TN, Matsuura K, Hiasa Y, et al.
- Journal Title
  
  Intervirology 48
  
  Pages: 262-267
- Data Source
  KAKENHI-PROJECT-17590650
[Journal Article] Hepatitis C virus acts as a tumor accelerator by blocking apoptosis in a mouse model of hepatocarcinogenesis.2005
- Author(s)
  Kamegaya Y, Hiasa Y, Zukerberg L, Fowler N, Blackard JT, Lin W, Choe WH, Schmidt EV, Chung RT.
- Journal Title
  
  Hepatology 41
  
  Pages: 660-667
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590650
[Journal Article] The quantification of cytochrome P-450 (CYP 3A4) mRNA in the blood of patients with viral liver diseases.2005
- Author(s)
  Horiike N, Abe M, Kumagi T, Hiasa Y, Akbar SM, Michitaka K, Onji M.
- Journal Title
  
  Clinical Biochemistry 38
  
  Pages: 531-534
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590650
[Journal Article] Hepatitis C virus expression suppresses interferon signaling by degrading STAT1.2005
- Author(s)
  Lin W, Choe WH, Hiasa Y, Kamegaya Y, Blackard JT, Schmidt EV, Chung RT.
- Journal Title
  
  Gastroenterology 128
  
  Pages: 1034-1041
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590650
[Journal Article] In vivo immunization by vaccine therapy following virus suppression by lamivudine : a novel approach for treating patients with chronic hepatitis B.2005
- Author(s)
  Horiike N, Akbar SMF, Michitaka K, Joukou K, Yamamoto K, Hiasa Y, et al.
- Journal Title
  
  Journal of Clinical Virology 32
  
  Pages: 156-161
- Data Source
  KAKENHI-PROJECT-17590650
[Journal Article] Hepatisis C virus acts as a tumor accelerator by blocking apoptosis in a mouse model of hepatocarcinogenesis.2005
- Author(s)
  Kamegaya Y, Hiasa Y, Zukerberg L, Fowler N, Blackard JT, et al.
- Journal Title
  
  Hepatology 41
  
  Pages: 660-667
- Data Source
  KAKENHI-PROJECT-17590650
[Journal Article] Administration of dendritic cells in cancer nodules in hepatocellular carcinoma.2005
- Author(s)
  Kumagi T, Akbar SM, Horiike N, Kurose K, Hiasa Y, et al.
- Journal Title
  
  Oncology Reports 14
  
  Pages: 969-973
- Data Source
  KAKENHI-PROJECT-17590650
[Journal Article] Hepatisis C virus acts as a tumor accelerator by blocking apoptosis in a mouse model of hepatocarcinogenesis.2005
- Author(s)
  Kamegaya Y, Hiasa Y, Zukerberg L., Fowler N, Blackard JT, et al.
- Journal Title
  
  Hepatology 41
  
  Pages: 660-667
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590650
[Journal Article] Major histocompatibility complex class-I presentation impaired in transgenic mice expressing hepatitis C virus structural proteins during dendritic cell maturation.2004
- Author(s)
  Hiasa Y, Takahashi H, Shimizu M, Nuriya H, Tsukiyama-Kohara K, et al.
- Journal Title
  
  Journal of Medical Virology 74
  
  Pages: 253-261
- Data Source
  KAKENHI-PROJECT-15790350
[Journal Article] CCR5 promotor polymorphism influences the interferon response of patients with chronic hepatitis C in Japan.2004
- Author(s)
  Konishi I, Horiike N, Hiasa, Y, Michitaka K, Onji M.
- Journal Title
  
  Intervirology 47
  
  Pages: 114-120
- Data Source
  KAKENHI-PROJECT-15790350
[Patent] B型肝炎ワクチン2017
- Inventor(s)
  小原道法、真田崇弘、日浅陽一、小原恭子、郷保正、織田康則
- Industrial Property Rights Holder
  小原道法、真田崇弘、日浅陽一、小原恭子、郷保正、織田康則
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2017-138047
- Filing Date
  2017
- Data Source
  KAKENHI-PROJECT-15K09006
[Patent] 体内での針先端を画像上に表示する針先端画像表示装置、それを用いたがん治療装置および体内での針先端を画像上に表示する針先端画像表示方法2014
- Inventor(s)
  廣岡昌史、日浅陽一
- Industrial Property Rights Holder
  廣岡昌史、日浅陽一
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2014-086806
- Filing Date
  2014-04-18
- Data Source
  KAKENHI-PROJECT-24590980
[Patent] ROMスコア及び肝細胞癌患者の客観的な予後予測方法2012
- Inventor(s)
  竹治智、日浅陽一、廣岡昌史、恩地森一
- Industrial Property Rights Holder
  竹治智、日浅陽一、廣岡昌史、恩地森一
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2012-273601
- Filing Date
  2012-12-14
- Data Source
  KAKENHI-PROJECT-24590980
[Patent] SEP(splenic elasticity for portal hypertension) score2011
- Inventor(s)
  日浅陽一、廣岡昌史、恩地森一
- Industrial Property Rights Holder
  日浅陽一、廣岡昌史、恩地森一
- Industrial Property Number
  2011-130701
- Filing Date
  2011-06-01
- Data Source
  KAKENHI-PROJECT-21590848
[Patent] SEP (splenic elasticity for portal hypertension) score2011
- Inventor(s)
  日浅陽一、廣岡昌史、恩地森一
- Industrial Property Rights Holder
  日浅陽一、廣岡昌史、恩地森一
- Industrial Property Number
  2011-130701
- Filing Date
  2011-06-01
- Data Source
  KAKENHI-PROJECT-21590848
[Presentation] 肝細胞癌進展における小胞体ストレス関連遺伝子PERKの役割2020
- Author(s)
  行本敦、渡辺崇夫、日浅陽一
- Organizer
  第56回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-18K08007
[Presentation] 肝細胞癌における Protein kinase R (PKR)の役割と、治療標的としての可能性2020
- Author(s)
  渡辺崇夫、今村健志、日浅陽一
- Organizer
  第24回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-18K08007
[Presentation] 肝細胞癌におけるprotein kinase R (PKR)の治療標的としての可能性2020
- Author(s)
  渡辺崇夫、二宮寛子、日浅陽一
- Organizer
  第79回日本癌学会学術集会
- Data Source
  KAKENHI-PROJECT-18K08007
[Presentation] 肝細胞癌におけるProtein kinase R (PKR)の組織バイオマーカーとしての役割と標的治療の可能性2020
- Author(s)
  渡辺崇夫、徳本良雄、日浅陽一
- Organizer
  第56回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-18K08007
[Presentation] The long noncoding RNA of RMRP induces apoptosis via PERK by ER stress in hepatocellular carcinoma.2020
- Author(s)
  Yukimoto Atsushi, Watanabe Takao, Sunago Kotaro, Tanaka Takaaki, Nakamura Yoshiko, Koizumi Yohei, Yoshida Osamu, Tokumoto Yoshio, Hirooka Masashi, Abe Masanori, Hiasa Yoichi.
- Organizer
  The Liver Meeting of American Association for the Study of Liver disease
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08007
[Presentation] Patients with HBV and HCV chronic liver disease under surveillance for HCC have a favorable long-term outcome for pancreatic cancer due to early diagnosis and high resection rate.2017
- Author(s)
  Kumagi T, Terao T, Hiasa Y, et al.
- Organizer
  American Association for the Study of Liver Diseases (AASLD)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09006
[Presentation] Validation of the GLOBE score and the UK-PBC risk score in Japanese patients.2017
- Author(s)
  Yoshida O, Abe M, Hiasa Y, et al.
- Organizer
  American Association for the Study of Liver Diseases (AASLD)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09006
[Presentation] Increased frequency of myeloid-derived suppressor cells in patients with non-alcoholic fatty liver disease.2017
- Author(s)
  Abe M, Nakamura Y, Hiasa Y, et al.
- Organizer
  American Association for the Study of Liver Diseases (AASLD)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09006
[Presentation] No-touch radio frequency ablation is an ideal method to prevent intrahepatic metastasis of hepatocellular carcinoma.2017
- Author(s)
  Hiraoka m, Hiraoka A, Hiasa Y, et al.
- Organizer
  American Association for the Study of Liver Diseases (AASLD)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09006
[Presentation] Comparison with Child-Pugh, liver damage and newly proposed ALBI-grade for assessment of hepatic function and predicting prognosis of Japanese patients with hepatocellular carcinoma.2017
- Author(s)
  Hiraoka A, Kumada T, Hiasa Y, et al.
- Organizer
  American Association for the Study of Liver Diseases (AASLD)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09006
[Presentation] Increase of serum chylomicron triglyceride concentration associated with intestinal overproduction of chylomicron triglyceride in nonobese, nondiabetic and normolipidemic NASH patients.2017
- Author(s)
  Utsunomiya H, Hanayama M, Hiasa Y, et al.
- Organizer
  American Association for the Study of Liver Diseases (AASLD)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09006
[Presentation] Protein kinase R modulates DNA methylation in hepatocellular carcinoma with HCV infection2016
- Author(s)
  Takao Watanabe, Yoshio Tokumoto, Masashi Hirooka, Osamu Yoshida, Yohei Koizumi, Yusuke Imai, Yoshiko Nakamura, Masanori Abe, Yoichi Hiasa
- Organizer
  25th Conference of the Asian pacific association for the study of the liver
- Place of Presentation
  グランドプリンスホテル新高輪、東京都港区
- Year and Date
  2016-02-20
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09006
[Presentation] Down-regulated acidic leucine-rich nuclear phosphoprotein 32 family member B (ANP32B) has a role in suppression of apoptosis, and is associated with poor prognosis in patients with hepatocellular carcinoma.2016
- Author(s)
  Ohio Y, Koizumi M, Hiasa Y, et al.
- Organizer
  The Liver Meeting of American Association for the Study of Liver Diseases
- Place of Presentation
  Boston, MA, USA
- Year and Date
  2016-11-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09006
[Presentation] Unregulated palmitic acid absorption with altered intestinal transporters in non-alcoholic steatohepatitis (NASH).2016
- Author(s)
  Utsunomiya H, Yamamoto Y, Hiasa Y, et al.
- Organizer
  The Liver Meeting of American Association for the Study of Liver Diseases
- Place of Presentation
  Boston, MA, USA
- Year and Date
  2016-11-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09006
[Presentation] The efficacy of radio frequency ablation combined with trans catheter hepatic chemoembolization for patients with BCLC stage B hepatocellular carcinoma.2016
- Author(s)
  Hirooka M, Hiraoka A, Hiasa Y, et al.
- Organizer
  The Liver Meeting of American Association for the Study of Liver Diseases
- Place of Presentation
  Boston, MA, USA
- Year and Date
  2016-11-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09006
[Presentation] The roles of protein kinase R and its possibility as a therapeutic target in hepatocellular carcinoma with hepatitis C virus infection.2016
- Author(s)
  Watanabe T, Tokumoto Y, Hiasa Y, et al.
- Organizer
  The Liver Meeting of American Association for the Study of Liver Diseases
- Place of Presentation
  Boston, MA, USA
- Year and Date
  2016-11-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09006
[Presentation] Patients with HBV and HCV chronic liver disease under surveillance for HCC are diagnosed with pancreatic cancer at early stages.2016
- Author(s)
  Kumagi T, Terao T, Hiasa Y, et al.
- Organizer
  The Liver Meeting of American Association for the Study of Liver Diseases
- Place of Presentation
  Boston, MA, USA
- Year and Date
  2016-11-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09006
[Presentation] HCV関連肝細胞癌におけるProtein kinase Rの役割2015
- Author(s)
  渡辺崇夫、日浅陽一
- Organizer
  第25回抗ウイルス療法学会総会
- Place of Presentation
  国立感染症研究所、東京都新宿区
- Year and Date
  2015-05-22
- Data Source
  KAKENHI-PROJECT-15K09006
[Presentation] C型肝細胞癌におけるProtein kinase Rの役割-c-Fos, c-Jun活性化を介した細胞増殖促進作用2015
- Author(s)
  渡辺崇夫、小泉光仁、日浅陽一
- Organizer
  日本がん分子標的治療学会第19回学術集会
- Place of Presentation
  松山全日空ホテル、愛媛県松山市
- Year and Date
  2015-06-10
- Data Source
  KAKENHI-PROJECT-15K09006
[Presentation] Nature of pathogenic and protective immunity in chronic hepatitis B virus infection2013
- Author(s)
  Sheikh Mohammad Fazle Akbar, Mamun A. Mahtab, Yoichi Hiasa, Julio Cesar Aguilar
- Organizer
  The 64th Annual Meeting of the American Association for the Study of Liver Diseases
- Place of Presentation
  Washington DC, USA
- Data Source
  KAKENHI-PROJECT-24590980
[Presentation] IgG4関連疾患診断における巻組織検査の有用性2013
- Author(s)
  熊木天児、日浅陽一、恩地森一
- Organizer
  第49回日本肝臓学会総会
- Place of Presentation
  東京　京王プラザホテル
- Data Source
  KAKENHI-PROJECT-24590980
[Presentation] Composition of serum fatty acids may be associated with the antiviral effects of interferon-based therapy in patients with hepatitis C virus infection2013
- Author(s)
  Teruki Miyake, Masashi Hirooka, Yoshio Tokumoto, Takao Watanabe, Teru Kumagi, Masanori Abe, Shinya Furukawa, Morikazu Onji, Bunzo Matsuura, Yoichi Hiasa
- Organizer
  The 64th Annual Meeting of the American Association for the Study of Liver Diseases
- Place of Presentation
  Washington DC, USA
- Data Source
  KAKENHI-PROJECT-24590980
[Presentation] Protein kinase R modulates c-Fos and c-Jun signaling to promote proliferation of hepatocellular carcinoma with hepatitis C virus infection2013
- Author(s)
  Takao Watanabe, Yoshio Tokumoto, Masashi Hirooka, Masanori Abe, Morikazu Onji, Raymond T. Chung, Yoichi Hiasa
- Organizer
  The 64th Annual Meeting of the American Association for the Study of Liver Diseases
- Place of Presentation
  Washington DC, USA
- Data Source
  KAKENHI-PROJECT-24590980
[Presentation] A phase III clinical trial with a therapeutic vaccine containing both HBsAg and HBcAg administered via both mucosal and parenteral routes in patients with chronic hepatitis B2013
- Author(s)
  Sheikh Mohammad Fazle Akbar, Mamun A. Mahtab, Salimur Rahman, Julio Cesar Aguilar, Yoichi Hiasa, Shunji Mishiro
- Organizer
  The 64th Annual Meeting of the American Association for the Study of Liver Diseases
- Place of Presentation
  Washington DC, USA
- Data Source
  KAKENHI-PROJECT-24590980
[Presentation] 新しいPIVKA-II分画(NX-PVKA)の肝細胞癌患者予後との関連2013
- Author(s)
  竹治智、廣岡昌史、日浅陽一
- Organizer
  第99回　日本消化器病学会総会
- Place of Presentation
  鹿児島県鹿児島市
- Data Source
  KAKENHI-PROJECT-24590980
[Presentation] Insertion of LINE-1 retrotranspozon in SLCO1B3 gene causes Rotor syndrome in Japanese patients2013
- Author(s)
  Tatehiro Kagawa, Kazuya Anzai, Kota Tsuruya, Yoshitaka Arase, Shunji Hirose, Koichi Shiraishi, Tsuneo Kitamura, Yoshinao Kobayashi, Yoichi Hiasa, Tetsuya Mine
- Organizer
  The 64th Annual Meeting of the American Association for the Study of Liver Diseases
- Place of Presentation
  Washington DC, USA
- Data Source
  KAKENHI-PROJECT-24590980
[Presentation] Virtual ultrasonography constructed by Gd-EOB- DTPA-enhanced magnetic resonance imaging is useful to avoid bile duct injury during radiofrequency ablatio2013
- Author(s)
  Yohei Koizumi, Masashi Hirooka, Hironori Ochi, Yoshio Tokumoto, Masanori Abe, Fujimasa Tada, Atsushi Hiraoka, Hiroaki Tanaka, Takaharu Tsuda, Teruhito Mochizuki, Yoichi Hiasa
- Organizer
  The 64th Annual Meeting of the American Association for the Study of Liver Diseases
- Place of Presentation
  Washington DC, USA
- Data Source
  KAKENHI-PROJECT-24590980
[Presentation] 治療前CTHA後期相を用いたfusion CTによる肝細胞癌局所療法治療効果判定2013
- Author(s)
  廣岡昌史、小泉洋平、日浅陽一
- Organizer
  第49回日本肝臓学会総会
- Place of Presentation
  東京　京王プラザホテル
- Data Source
  KAKENHI-PROJECT-24590980
[Presentation] 新たなPIVKA-II分画(NX-PVKA)の肝癌患者予後予測における臨床的有用性2013
- Author(s)
  竹治智、廣岡昌史、日浅陽一
- Organizer
  第17回日本肝臓学会大会
- Place of Presentation
  東京　グランドプリンス新高輪
- Data Source
  KAKENHI-PROJECT-24590980
[Presentation] Rapid absorption of dietary long-chain fatty acids with changes to intestinal fatty acid transporters in liver cirrhosis2013
- Author(s)
  Yasunori Yamamoto, Yoshio Ikeda, Eiji Tsubouchi, Hiroki Utsunomiya, Miyake Teruki, Hiroaki Nunoi, Morikazu Onji, Bunzo Matsuura, Yoichi Hiasa
- Organizer
  The 64th Annual Meeting of the American Association for the Study of Liver Diseases
- Place of Presentation
  Washington DC, USA
- Data Source
  KAKENHI-PROJECT-24590980
[Presentation] Trans-ethnic analyses of HLA-DPA1, DPB1 haplotypes to be associated with hepatitis B virus infection2013
- Author(s)
  Nao Nishida, Hiromi Sawai, Kouichi Kashiwase, Mutsuhiko Minami, Yoichi Hiasa, et al.
- Organizer
  The 64th Annual Meeting of the American Association for the Study of Liver Diseases
- Place of Presentation
  Washington DC, USA
- Data Source
  KAKENHI-PROJECT-24590980
[Presentation] An isoform of des-gamma-carboxy prothrombin (NX-PVKA) is a prognostic marker of hepatocellular carcinoma2013
- Author(s)
  Satoru Takeji, Masashi Hirooka, Yohei Koizumi, Hironori Ochi, Yoshio Tokumoto, Fujimasa Tada, Masanori Abe, Morikazu Onji, Yoichi Hiasa
- Organizer
  The 64th Annual Meeting of the American Association for the Study of Liver Diseases
- Place of Presentation
  Washington DC, USA
- Data Source
  KAKENHI-PROJECT-24590980
[Presentation] 薬物性肝障害の実態2012
- Author(s)
  堀池典生、上杉和寛、日浅陽一
- Organizer
  第16回　日本肝臓学会大会
- Place of Presentation
  兵庫県神戸市
- Data Source
  KAKENHI-PROJECT-24590980
[Presentation] 肝硬変患者における脂肪酸吸収変化とglycosylated CD36の役割2012
- Author(s)
  山本安則、池田宜央、日浅陽一
- Organizer
  第98回　日本消化器病学会総会
- Place of Presentation
  東京都新宿区
- Data Source
  KAKENHI-PROJECT-24590980
[Presentation] 肝細胞癌に対する抗原パルス樹状細胞を用いた免疫療法の第I/II相臨床試験2012
- Author(s)
  阿部雅則、多田藤政、廣岡昌史、小泉洋平、日浅陽一、恩地森一
- Organizer
  第48回　日本肝臓学会総会
- Place of Presentation
  石川県金沢市
- Data Source
  KAKENHI-PROJECT-24590980
[Presentation] NAFLDの肝線維化診断におけるReal-time tissue elastographyの有用性の検討2012
- Author(s)
  越智裕紀、廣岡昌史、日浅陽一
- Organizer
  第54回　日本消化器病学会大会
- Place of Presentation
  兵庫県神戸市
- Data Source
  KAKENHI-PROJECT-24590980
[Presentation] Characterization of ZNF689 in Human Hepatocellular Carcinoma as a Novel Target for Chemotherapy2011
- Author(s)
  Shigematsu S, Hiasa Y, Fukuda S, 他3名
- Organizer
  The 62th AASLD
- Place of Presentation
  San Francisco, USA
- Year and Date
  2011-11-04
- Data Source
  KAKENHI-PROJECT-21590848
[Presentation] Characterization of ZNF689 in Human Hepatocellular Carcinoma as a Novel Target for Chemotherapy2011
- Author(s)
  Shigematsu S, Hiasa Y, Fukuda S, 他3名、2番目
- Organizer
  The 62th American association for the study of liver disease
- Place of Presentation
  アメリカ合衆国、サンフランシスコ
- Year and Date
  2011-11-04
- Data Source
  KAKENHI-PROJECT-21590848
[Presentation] Up-regulated Wilms' tumor 1 gene functions in anti-apoptosis : potential therapeutic target for hepatocellular carcinoma2010
- Author(s)
  Uesugi K, Koizumi Y, Hiasa Y, (他8名、3番目)
- Organizer
  The 61th American association for the study of liver disease
- Place of Presentation
  アメリカ合衆国、ボストン
- Year and Date
  2010-11-01
- Data Source
  KAKENHI-PROJECT-21590848
[Presentation] Up-regulated Wilms' tumor 1 gene functions in anti-apoptosis : potential therapeutic target for hepatocellular carcinoma2010
- Author(s)
  Uesugi K, Koizumi Y, Hiasa Y, 他8名
- Organizer
  The 61th AASLD
- Place of Presentation
  Boston, USA
- Year and Date
  2010-11-01
- Data Source
  KAKENHI-PROJECT-21590848
[Presentation] Decrease of SOCS-3 by ME3738 contributes to its synergistic anti-HCV effects when combined with type I interferon2009
- Author(s)
  Hiasa Y, Tokumoto Y, Konishi I, 他4名
- Organizer
  The 60th AASLD
- Place of Presentation
  Boston, USA
- Year and Date
  2009-11-03
- Data Source
  KAKENHI-PROJECT-21590848
[Presentation] Decrease of SOCS-3 by ME3738 contributes to its synergistic anti-HCV effects when combined with type I interferon2009
- Author(s)
  Hiasa Y, Tokumoto Y, Konishi I, 他4名, 1番目
- Organizer
  The 60th American association for the study of liver disease
- Place of Presentation
  アメリカ合衆国、ボストン
- Year and Date
  2009-11-03
- Data Source
  KAKENHI-PROJECT-21590848
[Presentation] HepG2細胞におけるME3738による内因性IFN-βの増加とその抗HCV 効果2008
- Author(s)
  日浅陽一、徳本良雄、小西一郎(他2名, 1番目)
- Organizer
  第50回日本消化器病学会大会
- Place of Presentation
  東京
- Year and Date
  2008-10-01
- Data Source
  KAKENHI-PROJECT-19590771
[Presentation] リバビリンによるインターフェロン誘導遺伝子の修飾と治療効果への役割2008
- Author(s)
  徳本良雄、日浅陽一、恩地森一
- Organizer
  第44回日本肝臓学会総会
- Place of Presentation
  松山
- Year and Date
  2008-06-05
- Data Source
  KAKENHI-PROJECT-19590771
[Presentation] Ribavirin upregulates autocrine interferon-β and interferon stimulated genes in the early phase of the combination treatment with interferon-α2008
- Author(s)
  Tokumoto Y, Hiasa Y, Konishi I(他4名, 2番目)
- Organizer
  第59回米国肝臓学会
- Place of Presentation
  San Francisco, CA, USA
- Year and Date
  2008-11-03
- Data Source
  KAKENHI-PROJECT-19590771
[Presentation] The enhancement of autocrine interferon-beta and the decrease of SOCS-3 by ME3738 would contribute the synergistic anti-HCV effects combined with interferon-alpha2008
- Author(s)
  Hiasa Y, Tokumoto Y, Konishi I, (他2名, 1番目).
- Organizer
  The 59^<th> Annual Meeting of the American Association for the Study of Liver Diseases
- Place of Presentation
  San Francisco, CA, USA
- Year and Date
  2008-11-04
- Data Source
  KAKENHI-PROJECT-19590771
[Presentation] The enhancement of autocrine interferon-beta and the decrease of SOCS-3 by ME3738 would contribute the synergistic anti-HCV effects combined with interferon-alpha2008
- Author(s)
  Hiasa Y, Tokumoto Y, Konishi I(他2名, 1番目)
- Organizer
  第59回米国肝臓学会
- Place of Presentation
  San Francisco, CA, USA
- Year and Date
  2008-11-04
- Data Source
  KAKENHI-PROJECT-19590771
[Presentation] ME3738とインターフェロン併用による抗HCV効果の基礎的検討2007
- Author(s)
  日浅陽一、徳本良雄、小西一郎(他5名, 1番目)
- Organizer
  第11回日本肝臓学会大会
- Place of Presentation
  神戸
- Year and Date
  2007-10-18
- Data Source
  KAKENHI-PROJECT-19590771
[Presentation] ME3738 inhibits hepatitis C virus replication by enhancing interferon-beta2007
- Author(s)
  Hiasa Y, Tokumoto Y, Konishi I(他4名, 1番目)
- Organizer
  第58回米国肝臓学会
- Place of Presentation
  Boston, MA, USA
- Year and Date
  2007-11-06
- Data Source
  KAKENHI-PROJECT-19590771
[Presentation] ME3738 inhibits hepatitis C virus replication by enhancing interferon-beta2007
- Author(s)
  Hiasa Y, Tokumoto Y, Konishi I, Matsuura B, et. al.
- Organizer
  The 58^<th> Annual Meeting of the American Association for the Study of Liver Diseases
- Place of Presentation
  Boston,MA,USA
- Year and Date
  2007-11-06
- Data Source
  KAKENHI-PROJECT-19590771
[Presentation] 高齢者(65歳以上)のC型慢性肝炎患者における抗ウイルス治療効果2007
- Author(s)
  日浅陽一、小西一郎、世良俊樹(他4名, 1番目)
- Organizer
  第37回日本肝臓学会西部会
- Place of Presentation
  長崎
- Year and Date
  2007-12-08
- Data Source
  KAKENHI-PROJECT-19590771
[Presentation] C型肝炎に対する免疫療法2007
- Author(s)
  日浅陽一、眞柴寿枝、恩地森一
- Organizer
  第43回日本肝臓学会総会
- Place of Presentation
  東京
- Year and Date
  2007-05-31
- Data Source
  KAKENHI-PROJECT-19590771
[Presentation] Branched-chain amino acids improve intestinal malabsorption of dietary long-chain fatty acids and preserve intestinal fatty acid transporters in liver cirrhosis.
- Author(s)
  Yamamoto Y, Utsunomiya H, Hiasa Y, et al.
- Organizer
  The 65th Annual Meeting of the American Association for the Study of Liver Diseases
- Place of Presentation
  Boston, USA
- Year and Date
  2014-11-07 – 2014-11-11
- Data Source
  KAKENHI-PROJECT-24590980
[Presentation] Wisteria floribunda agglutinin-positive Mac-2 binding protein as a predictor of liver fibrosis in patients with non-alcoholic fatty liver disease.
- Author(s)
  Abe M, Miyake T, Hiasa Y, et al.
- Organizer
  The 65th Annual Meeting of the American Association for the Study of Liver Diseases
- Place of Presentation
  Boston, USA
- Year and Date
  2014-11-07 – 2014-11-11
- Data Source
  KAKENHI-PROJECT-24590980
[Presentation] Oral glucose tolerance test predicts hepatic fibrosis in nonalcoholic fatty liver disease patients without overt diabetes mellitus.
- Author(s)
  Nishina S, Hyogo H, Hiasa Y, et al.
- Organizer
  The 65th Annual Meeting of the American Association for the Study of Liver Diseases
- Place of Presentation
  Boston, USA
- Year and Date
  2014-11-07 – 2014-11-11
- Data Source
  KAKENHI-PROJECT-24590980
[Presentation] Pancreatic congestion in liver cirrhosis correlates with impaired insulin secretion.
- Author(s)
  Kuroda T, Hirooka M, Hiasa Y, et al.
- Organizer
  The 65th Annual Meeting of the American Association for the Study of Liver Diseases
- Place of Presentation
  Boston, USA
- Year and Date
  2014-11-07 – 2014-11-11
- Data Source
  KAKENHI-PROJECT-24590980
[Presentation] Portal hypertension due to outflow block in non-cirrhotic patients with nonalcoholic fatty liver disease.
- Author(s)
  Koizumi Y, Hirooka M, Hiasa Y, et al.
- Organizer
  The 65th Annual Meeting of the American Association for the Study of Liver Diseases
- Place of Presentation
  Boston, USA
- Year and Date
  2014-11-07 – 2014-11-11
- Data Source
  KAKENHI-PROJECT-24590980

1. Furukawa Shinya (60444733)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. ONJI Morikazu (10112260)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 廣岡昌史 (30432785)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. 谷川武 (80227214)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. MATSUURA Bunzo

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
6. KONDO Yasuteru

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. ASAHINA Yasuhiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. NOUSO Kazuhiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. KORENAGA Masaaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
10. ITO Yuri

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. KANTO Tatsuya

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 熊木天児

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results
13. 安居幸一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 西田直生志

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 本多政夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 阿部雅則

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results
17. 徳永勝士

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 田中純子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 田中詩織

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 三宅映己

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
21. 渡辺崇夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
22. 溝上雅史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

HIASA Yoichi 日浅 陽一

日浅 陽一 ビアサ ヨウイチ

Research Projects

Research Products

Co-Researchers

Role of endoplasmic reticulum stress response proteins, PERK and eIF2, in hepatocarcinogenesis progression.Principal Investigator

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Potential for targeted therapy of eIF2, a PKR-related molecule involved in carcinogenesis and progression of hepatocellular carcinoma.Principal Investigator

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The role of ER stress and PERK for chronic liver injury and hepatocarcinogenesisPrincipal Investigator

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Review Section

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The role of protein kinase R (PKR) for hepatocarcinogenesis and progression of hepatocellular carcinoma during inflammation due to hepatitis C virus infection.Principal Investigator

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The association between sleep-disordered breathing and prognosis among patients with liver diseases:

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The role of PKR and its modification to the function of host cell in hepatocellular carcinomaPrincipal Investigator

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Investigation about the role of WT1 and PKR for the carcinogenesis or progression of hepatocellular carcinomaPrincipal Investigator

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Research about the key molecule to contribute for hepatitis C virus elimination from the aspect of liver host cell and immune cellsPrincipal Investigator

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Identification of the key molecules for hepatitis C virus (HCV) replication and the translation research for the noble protocols against HCV using cell-based HCV replication model.Principal Investigator

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C型肝炎ウイルス(HCV)複製モデルを用いたHCV増殖に伴う肝発癌機序の解明Principal Investigator

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Study about mechanism of action of vaccine therapy and their antiviral potential: development of more potent and new regimen of vaccine therapy

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C型肝炎ウィルス遺伝子発現によって生じる抗原提示樹状細胞の機能異常が発生する機序Principal Investigator

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[Book] 第31回犬山シンポジウム -B型肝炎・C型肝炎・肝癌2018

Author(s)

Total Pages

HIASA Yoichi 日浅陽一

日浅陽一ビアサヨウイチ

[Book] 消化器疾患　最新の治療　2017-20182017

[Book] 消化器疾患　最新の治療2017-20182017

[Book] 臨牀消化器内科　10月号2016

[Book] Bio Clinica 「7 DAAによる治療困難例への挑戦、肝移植例　他」2013

[Book] 愛媛大学における急性肝炎症例の解析わが国における急性肝炎の現状　全国調査2008-20112012