Morisada Tohru 森定徹

… Alternative Names

森定徹モリサダトオル

MORISADA TOHRU 森定徹

MORISADA Tooru 森定徹

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Researcher Number	70317923
Other IDs
Affiliation (Current)	2025: 杏林大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2022 – 2023: 杏林大学, 医学部, 准教授 2015: 慶應義塾大学, 医学部, 助教 2013: 慶應義塾大学, 医学部, 助教 2009: 慶応義塾大学, 医学部, 助教 2007: Keio University, 医学部, 助教 2005 – 2006: 慶應義塾大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Obstetrics and gynecology / Basic Section 56040:Obstetrics and gynecology-related Except Principal Investigator Biological Sciences / General surgery
Keywords	Principal Investigator リンパ管腫 / 卵巣明細胞癌 / メトホルミン / 卵巣癌 / 婦人科悪性腫瘍 / リンパ管内皮細胞 / 転移 / 悪性腫瘍 / リンパ管 Except Principal Investigator 抗体 … More / アンジオポエチン / リンパ管新生 / 転移 / アンジオポエチン様因子 / がん転移 / がん / 血管新生 / リンパ管 / Prox1 / D2-40 / Podolanin / FACS / 培養 / 転写因子 / epigenetic / HUVEC / RLGS / 不死化 / リンパ管内皮細胞 / リンパ管腫 Less

Elucidation of the molecular mechanism of the antitumor effect of metformin in refractory ovarian clear cell carcinomaPrincipal Investigator
- Principal Investigator
  
  森定徹
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Kyorin University
Analysis of molecular mechanism of lymphatic metastasis of gynecologic malignant tumorPrincipal Investigator
- Principal Investigator
  
  MORISADA TOHRU
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Keio University
悪性腫瘍のリンパ行性転移を制御する分子機構の解明Principal Investigator
- Principal Investigator
  
  森定徹
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Keio University
Identification of molecular mechanisms underlying lymphangiogenesis and angiogenesis in tumor progression and metastasis
- Principal Investigator
  
  OIKE Yui chi
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kumamoto University
  Keio University
リンパ管関連疾患攻略に向けたヒトリンパ管内皮細胞の網羅的スクリーニング
- Principal Investigator
  
  森川康英
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  General surgery
- Research Institution
  Keio University

All 2023 2022 2015 2008 2007 2006 2005

All Journal Article Presentation Book

[Book] アンジオポエチン様因子と病態(癌と血管新生の分子生物学分担)(渋谷正史編)2006
- Author(s)
  羽藤泰, 森定徹, 尾池雄一
- Total Pages
  190
- Publisher
  南山堂
- Data Source
  KAKENHI-PROJECT-17014078
[Book] 癌と血管新生の分子生物学分担:アンジオポエチン様因子と病態2006
- Author(s)
  羽藤泰, 森定徹, 尾池雄一
- Publisher
  南山堂(印刷中)
- Data Source
  KAKENHI-PROJECT-17014078
[Journal Article] 悪性腫瘍におけるリンパ管新生2015
- Author(s)
  森定徹、青木大輔
- Journal Title
  
  産科と婦人科
  
  Volume: 82(2) Pages: 147-153
- Data Source
  KAKENHI-PROJECT-25462613
[Journal Article] Angiopoietin-related growth factor enhances blood flow via activation of the ERK1/2-eNOS-NO pathway in a mouse hind-limb ischemia model.2008
- Author(s)
  Urano T., Ito Y., Akao M., Sawa T., Miyata K., Tabata M., Morisada T., Hato T., Kadomatsu T., Yano T., Yasunaga K., Shibata R., Murohara T., Akaike T., Tanihara H., Suda T., Oike Y.
- Journal Title
  
  Arterioscler Thromb Vasc Biol 28
  
  Pages: 827-834
- Data Source
  KAKENHI-PROJECT-17014078
[Journal Article] Angiogenic role of LYVE-1-positive macrophages in adipose tissue.2007
- Author(s)
  Cho CH., Jun Koh Y., Han J., Sung HK., Jong Lee H., Morisada T., Schwendener RA., Brekken RA., Kang G., Oike Y., Choi TS., Suda T., Yoo OJ., Koh GY.
- Journal Title
  
  Circ Res 100
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014078
[Journal Article] Prox1 induces lymphatic endothelial differentiation via integrin a9 and other signaling cascades.2007
- Author(s)
  Mishima K., Watabe T., Saito A., Yoshimatsu Y., Imaizumi N., Masui S., Hirashima M., Morisada T., Oike Y., Araie M., Niwa H., Kubo H., Suda T., Miyazono K.
- Journal Title
  
  Mol Biol Cell 18
  
  Pages: 1421-1429
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014078
[Journal Article] Spreds are essential for embryonic lymphangiogenesis by regulating vascular endothelial growth factor receptor-3 signaling.2007
- Author(s)
  Taniguchi K., Kohno R., Ayada T., Kato R., Morisada T., Oike Y., Yonemitsu Y., Maehara Y., Yoshimura, A.
- Journal Title
  
  Mol Cell Biol 27
  
  Pages: 4541-4550
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014078
[Journal Article] Angiopoietins and Angiopoietin-like proteins in angiogenesis2006
- Author(s)
  Morisada, T. et al.
- Journal Title
  
  Endothelium 13・2
  
  Pages: 71-79
- Data Source
  KAKENHI-PROJECT-17014078
[Journal Article] Loss of Tie2 receptor compromises embryonic stem cell-derived endothelial but not hematopoietic cell survival.2006
- Author(s)
  Hamaguchi I., Morisada T., Azuma M., Murakami K., Kuramitsu M., Mizukami T., Ohbo K., Yamaguchi K., Oike Y., Dumont DJ., Suda T.
- Journal Title
  
  Blood 107
  
  Pages: 1207-1213
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014078
[Journal Article] Angiopoietins and Angiopoietin-like proteins in angiogenesis.2006
- Author(s)
  Morisada T., Kubota Y., Urano T., Suda T., Oike Y. *
- Journal Title
  
  Endothelium 13
  
  Pages: 71-79
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014078
[Journal Article] Distribution of lymphatic vessels in mouse thymus: immunofluorescence analysis.2006
- Author(s)
  Odaka C., Morisada T., Oike Y., Suda T.
- Journal Title
  
  Cell Tissue Res 325
  
  Pages: 13-22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014078
[Journal Article] Intestinal and peri-tumoral lymphatic endothelial cells are resistant to radiation-induced apoptosis.2006
- Author(s)
  Sung HK., Morisada T., Cho CH., Oike Y., Lee J., Sung EK., Chung JH., Suda T., Koh GY.
- Journal Title
  
  Biochem Biophys Res Commun 345
  
  Pages: 545-551
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014078
[Journal Article] Angiopoietin-1 promotes LYVE-1-positive lymphatic vessel formation2005
- Author(s)
  Morisada T. et al.
- Journal Title
  
  Blood 105・12
  
  Pages: 4649-4656
- NAID
  120001129412
- Data Source
  KAKENHI-PROJECT-17014078
[Journal Article] Isolation and expression patterns of genes for three angiopoietin-like proteins, Angptl1, 2 and 6 in zebrafish.2005
- Author(s)
  Kubota Y., Oike Y, Satoh S., Tabata Y., Niikura Y., Morisada T., Akao M., Urano T., Ito Y., Miyamoto T., Watanabe S., Suda T.
- Journal Title
  
  Gene Expr Patterns 5
  
  Pages: 679-685
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014078
[Journal Article] Angiopoietin-1 promotes LYVE-1-positive lymphatic vessel formation.2005
- Author(s)
  Morisada T., Oike Y. *, Yamada Y., Urano T., Akao M., Kubota Y., Maekawa H., Kimura Y., Ohmura M., Miyamoto T., Nozawa S., Koh GY., Alitalo K., Suda T.
- Journal Title
  
  Blood 105
  
  Pages: 4649-4656
- NAID
  120001129412
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014078
[Journal Article] Angiopoietin-1 promotes lymphatic sprouting and hyperplasia.2005
- Author(s)
  Tammela T., SaaristoA., Lohela M., Morisada T., Tornberg J., Norrmen C., Oike Y., Pajusola K., Thurston G., Suda T., Yla-Herttuala S., Alitalo K.
- Journal Title
  
  Blood 105
  
  Pages: 4642-4648
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014078
[Journal Article] Cooperative interaction of Angiopoietin-like proteins 1 and 2 in zebrafish vascular development.2005
- Author(s)
  Kubota Y., Oike Y. *, Satoh S., Tabata Y., Niikura Y., Morisada T., Akao M., Urano T., Ito Y., Miyamoto T., Nagai N., Koh GY., Watanabe S., Suda T.
- Journal Title
  
  Proc Natl Acad Sci USA 102
  
  Pages: 13502-13507
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014078
[Presentation] ヒト卵巣明細胞癌細胞株を用いたメトホルミンの抗腫瘍効果の検討2023
- Author(s)
  竹森聖、森定徹ら
- Organizer
  第44回日本エンドメトリオーシス学会学術講演会
- Data Source
  KAKENHI-PROJECT-22K09603
[Presentation] 卵巣明細胞癌におけるメトホルミンの抗腫瘍効果2023
- Author(s)
  竹森聖, 森定徹, 尾坂真, 渡邉百恵, 田嶋敦, 谷垣伸治, 小林陽一
- Organizer
  第41回日本ヒト細胞学会学術集会
- Data Source
  KAKENHI-PROJECT-22K09603
[Presentation] Analysis of anti-cancer effects of metformin on ovarian clear cell carcinoma cells2022
- Author(s)
  Satoshi Takemori, Tohru Morisada et al.
- Organizer
  第74回日本産科婦人科学会学術講演会
- Data Source
  KAKENHI-PROJECT-22K09603
[Presentation] リンパ管腫由来の不死化リンパ管内皮細胞の樹立2007
- Author(s)
  森定徹
- Organizer
  第59回日本産科婦人科学会学術講演会
- Place of Presentation
  京都市
- Year and Date
  2007-04-16
- Data Source
  KAKENHI-PROJECT-18791176
[Presentation] アンジオポエチンファミリーと血管・リンパ管-血管・リンパ管標的療法を目指して-2006
- Author(s)
  尾池雄一、森定徹、羽藤泰
- Organizer
  第65回日本癌学会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-17014078
[Presentation] リンパ管形成の分子基盤解明2005
- Author(s)
  尾池雄一、森定徹、須田年生
- Organizer
  第28回日本分子生物学会
- Place of Presentation
  福岡・国立病院機構九州医療センター
- Data Source
  KAKENHI-PROJECT-17014078

1. OIKE Yui chi (90312321)

# of Collaborated Projects: 2 results

# of Collaborated Products: 16 results
2. FUJINO Akihiro (50306726)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 森川康英 (90124958)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 星野健 (70190197)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Morisada Tohru 森定 徹

森定 徹 モリサダ トオル

MORISADA TOHRU 森定 徹

MORISADA Tooru 森定 徹

Research Projects

Research Products

Co-Researchers

Elucidation of the molecular mechanism of the antitumor effect of metformin in refractory ovarian clear cell carcinomaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of molecular mechanism of lymphatic metastasis of gynecologic malignant tumorPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

悪性腫瘍のリンパ行性転移を制御する分子機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification of molecular mechanisms underlying lymphangiogenesis and angiogenesis in tumor progression and metastasis

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

リンパ管関連疾患攻略に向けたヒトリンパ管内皮細胞の網羅的スクリーニング

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] アンジオポエチン様因子と病態(癌と血管新生の分子生物学分担)(渋谷正史 編)2006

Author(s)

Total Pages

Publisher

Data Source

[Book] 癌と血管新生の分子生物学 分担:アンジオポエチン様因子と病態2006

Author(s)

Publisher

Data Source

[Journal Article] 悪性腫瘍におけるリンパ管新生2015

Author(s)

Journal Title

Data Source

[Journal Article] Angiopoietin-related growth factor enhances blood flow via activation of the ERK1/2-eNOS-NO pathway in a mouse hind-limb ischemia model.2008

Author(s)

Journal Title

Data Source

[Journal Article] Angiogenic role of LYVE-1-positive macrophages in adipose tissue.2007

Author(s)

Journal Title

Data Source

[Journal Article] Prox1 induces lymphatic endothelial differentiation via integrin a9 and other signaling cascades.2007

Author(s)

Journal Title

Data Source

[Journal Article] Spreds are essential for embryonic lymphangiogenesis by regulating vascular endothelial growth factor receptor-3 signaling.2007

Author(s)

Journal Title

Data Source

[Journal Article] Angiopoietins and Angiopoietin-like proteins in angiogenesis2006

Author(s)

Journal Title

Data Source

[Journal Article] Loss of Tie2 receptor compromises embryonic stem cell-derived endothelial but not hematopoietic cell survival.2006

Author(s)

Journal Title

Data Source

[Journal Article] Angiopoietins and Angiopoietin-like proteins in angiogenesis.2006

Author(s)

Journal Title

Data Source

[Journal Article] Distribution of lymphatic vessels in mouse thymus: immunofluorescence analysis.2006

Author(s)

Morisada Tohru 森定徹

森定徹モリサダトオル

MORISADA TOHRU 森定徹

MORISADA Tooru 森定徹

[Book] アンジオポエチン様因子と病態(癌と血管新生の分子生物学分担)(渋谷正史編)2006

[Book] 癌と血管新生の分子生物学分担:アンジオポエチン様因子と病態2006