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Sasaki Jun  佐々木 潤

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SASAKI Jun  佐々木 潤

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Researcher Number 70319268
Other IDs
Affiliation (Current) 2025: 藤田医科大学, 医学部, 講師
Affiliation (based on the past Project Information) *help 2025: 藤田医科大学, 医学部, 講師
2018 – 2023: 藤田医科大学, 医学部, 講師
2013 – 2017: 藤田保健衛生大学, 医学部, 講師
2009 – 2011: Fujita Health University, 医学部, 講師
2002 – 2007: 藤田保健衛生大学, 医学部, 講師
2000 – 2001: 藤田保健衛生大学, 医学部, 助手
Review Section/Research Field
Principal Investigator
Virology / Basic Section 49060:Virology-related / Virology
Except Principal Investigator
寄生虫学(含医用動物学) / Virology
Keywords
Principal Investigator
ピコルナウイルス / アイチウイルス / ゲノム複製 / コレステロール / ピコルナウイルス複製 / RNAウイルス / PI4P / ACBD3 / 宿主因子 / ウイルスRNAの複製 … More / 非翻訳領域 / ステム-ループ構造 / 宿主特異性 / IFITM1 / 複製オルガネラ / IFTM1 / 複製機構 / 感染症 / 脂質代謝 / コレステロール輸送 / ウイルスゲノム複製 / OSBP / PI4KB / 複製複合体 / シュードノット構造 / パッケージング / RNA replication / 2A protein / Leader protein … More
Except Principal Investigator
IL-12 / IFN-γ / Neuroglia cell / Macrophage / Malaria granuloma / Th1-mediated immunity / Osteopontin / Malaria / ノックアウトマウス / 一酸化窒素 / ネズミマラリア / IFN-gamma / RT-PCR / マラリアグラニュローマ / ベトナム / TNF-alha / 脳マラリア / 熱帯熱マラリア / グリア細胞 / マクロファージ / IL-2 / 肉芽腫 / 細胞性免疫 / マラリア / オステオポンチン / Gastroenteritis / Artificially Infectious Particle / Simian Rotavirus / VP4 gene / Reverse Genetics / Human Rotavirus / キメラウイルス / トリプシン依存性 / リアソートメント / ロタウイルス / ヒトロタルス / 胃腸炎 / 人工感染粒子 / サルロタウイルス / VP4遺伝子 / リバースジェネテックス / ヒトロタウイルス Less
  • Research Projects

    (11 results)
  • Research Products

    (30 results)
  • Co-Researchers

    (3 People)
  •  アイチウイルスの組織指向性およびインターフェロン応答抑制機構の解析Principal Investigator

    • Principal Investigator
      佐々木 潤
    • Project Period (FY)
      2025 – 2028
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49060:Virology-related
    • Research Institution
      Fujita Health University
  •  Analysis of host and viral proteins required for cholesterol accumulation at the AIchi virus genome replication site.Principal Investigator

    • Principal Investigator
      Sasaki Jun
    • Project Period (FY)
      2020 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49060:Virology-related
    • Research Institution
      Fujita Health University
  •  Analysis of host factors required for Aichi virus genome replicationPrincipal Investigator

    • Principal Investigator
      Sasaki Jun
    • Project Period (FY)
      2016 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Virology
    • Research Institution
      Fujita Health University
  •  Analysis of formation of Aichi virus replication complexesPrincipal Investigator

    • Principal Investigator
      Sasaki Jun
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Virology
    • Research Institution
      Fujita Health University
  •  Analysis of the mechanism of Aichi virus replication complex formation.Principal Investigator

    • Principal Investigator
      SASAKI Jun
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Virology
    • Research Institution
      Fujita Health University
  •  アイチウイルスの複製に関与するウイルスタンパク質および宿主タンパク質の機能解析Principal Investigator

    • Principal Investigator
      佐々木 潤
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Virology
    • Research Institution
      Fujita Health University
  •  アイチウイルスのゲノム複製とencapsidationの分子機構Principal Investigator

    • Principal Investigator
      佐々木 潤
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Virology
    • Research Institution
      Fujita Health University
  •  新規ピコルナウイルスであるアイチウイルスのゲノム非翻訳領域の機能解析Principal Investigator

    • Principal Investigator
      佐々木 潤
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Virology
    • Research Institution
      Fujita Health University
  •  Development of the system for the formation of infectious particles of rotavirus with the aid of genetic engineering

    • Principal Investigator
      TANIGUCHI Koki
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Virology
    • Research Institution
      FUJITA HEALTH UNIVERSITY
  •  Studies on osteopontin : its expression and function in Plasmodium parasites infection

    • Principal Investigator
      MAENO Yoshimasa
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      寄生虫学(含医用動物学)
    • Research Institution
      Fujita Health University
  •  新たに発見された愛知ウイルスの感染性cDNAを利用した非構造タンパク質の機能解析Principal Investigator

    • Principal Investigator
      佐々木 潤
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Virology
    • Research Institution
      Fujita Health University

All 2023 2021 2019 2018 2015 2014 2012 2011 2010 2009 2007 2005 2003

All Journal Article Presentation

  • [Journal Article] IFITM1 enhances nonenveloped viral RNA replication by facilitating cholesterol transport to the Golgi2023

    • Author(s)
      Ishikawa-Sasaki K, Murata T, Sasaki J
    • Journal Title

      Plos Pathgens

      Volume: 19 Issue: 5 Pages: e1011383-e1011383

    • DOI

      10.1371/journal.ppat.1011383

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K07529
  • [Journal Article] Bacterial Stabilization of a Panel of Picornaviruses2019

    • Author(s)
      Aguilera Elizabeth R.、Nguyen Y、Sasaki Jun、Pfeiffer Julie K.
    • Journal Title

      mSphere

      Volume: 4 Issue: 2

    • DOI

      10.1128/msphere.00183-19

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08819
  • [Journal Article] Model of OSBP-Mediated Cholesterol Supply to Aichi Virus RNA Replication Sites Involving Protein-Protein Interactions among Viral Proteins, ACBD3, OSBP, VAP-A/B, and SAC12018

    • Author(s)
      Ishikawa-Sasaki Kumiko、Nagashima Shigeo、Taniguchi Koki、Sasaki Jun
    • Journal Title

      Journal of Virology

      Volume: 92 Issue: 8

    • DOI

      10.1128/jvi.01952-17

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K08819
  • [Journal Article] A Complex Comprising Phosphatidylinositol 4-Kinase IIIβ, ACBD3, and Aichi Virus Proteins Enhances Phosphatidylinositol 4-Phosphate Synthesis and Is Critical for Formation of the Viral Replication Complex.2014

    • Author(s)
      Kumiko Ishikawa-Sasaki, Jun Sasaki, Koki Taniguchi
    • Journal Title

      J Virol

      Volume: 88 Issue: 12 Pages: 6586-6598

    • DOI

      10.1128/jvi.00208-14

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25460572
  • [Journal Article] ACBD3-mediated recruitment of PI4KB to picornavirus RNA replication sites2012

    • Author(s)
      Sasaki J, Ishikawa K, Arita M, Taniguchi K
    • Journal Title

      EMBO J

      Volume: 31 Issue: 3 Pages: 754-766

    • DOI

      10.1038/emboj.2011.429

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590514
  • [Journal Article] 3CD, but not 3C, cleaves the VP1/2A site efficiently during Ai chi virus polyprotein processing through interaction with 2A2012

    • Author(s)
      Sasaki J, Ishikawa K, Taniguchi K
    • Journal Title

      Virus Res

      Volume: 163 Pages: 592-598

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590514
  • [Journal Article] 3CD, but not 3C, cleaves the VP1/2A site efficiently during Aichi virus polyprotein processing through interaction with 2A2012

    • Author(s)
      Sasaki J, Ishikawa K, Taniguchi K
    • Journal Title

      Virus Res

      Volume: 163 Issue: 2 Pages: 592-598

    • DOI

      10.1016/j.virusres.2011.12.013

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590514
  • [Journal Article] ACBD3? mediated recruitment of PI4KB to picornavirus RNA replication sites2012

    • Author(s)
      Sasaki J, Ishikawa K, Arita M, Taniguchi K
    • Journal Title

      EMBO J

      Volume: 31 Pages: 754-766

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590514
  • [Journal Article] Overall linkage map of the nonstructural proteins of Aichi virus2010

    • Author(s)
      Ishikawa K, Sasaki J, Taniguchi K
    • Journal Title

      Virus Res

      Volume: 147 Pages: 77-84

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590514
  • [Journal Article] The 5'-terminal region of the Aichi virus genome encodes cis-acting replication elements required for positive- and negative-strand RNA synthesis.2005

    • Author(s)
      S.Nagashima, J.Sasaki, K.Taniguchi
    • Journal Title

      Journal of Virology 79

      Pages: 6918-6931

    • Data Source
      KAKENHI-PROJECT-16790275
  • [Journal Article] The 5'-terminal region of the Aichi virus genome encodes cis-acting replication elements required for positive- and negative-strand RNA.2005

    • Author(s)
      Shigeo Nagashima, Jun Sasaki, Koki Taniguchi
    • Journal Title

      Journal of Virology (In press)

    • Data Source
      KAKENHI-PROJECT-16790275
  • [Journal Article] Osteopontin participates in Thl-mediated host resistance against nonletha malaria parasite Plasmodium chabaudi chabaudi infection in mice.2005

    • Author(s)
      Maeno Y, Nakazawa S, Yamamoto N, Shinzato M, Nagashima S, Tanaka K, Sasaki J, Uede T, Taniguchi K.
    • Journal Title

      Infect Immun (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14570225
  • [Journal Article] The 5'-end sequence of the genome of Aichi virus, a Picornavirus, contains an element critical for viral RNA encapsidation.2003

    • Author(s)
      Sasaki J, Taniguchi K
    • Journal Title

      J Virol 77(6)

      Pages: 3542-3548

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370105
  • [Journal Article] Functional analysis of the stem-loop structures at the 5' end of the Aichi virus genome.2003

    • Author(s)
      Nagashima S, Sasaki J, Taniguchi K
    • Journal Title

      Virology 39(11)

      Pages: 3969-3975

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370105
  • [Journal Article] The Aichi virus leader protein is involved in viral RNA replication and encapsidation.2003

    • Author(s)
      Sasaki J, Nagashima S, Taniguchi K
    • Journal Title

      J Virol 77(11)

      Pages: 10799-10807

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370105
  • [Journal Article] The Aichi virus leader protein is involved in viral RNA replication and encapsidation.2003

    • Author(s)
      Sasaki J et al.
    • Journal Title

      Journal of Virology 77

      Pages: 10799-10807

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14370105
  • [Journal Article] The 5'-end sequence of the genome of Aichi virus, a Picornavirus, contains an elementcritical for viral RNA encapsidation.2003

    • Author(s)
      Sasaki J, Taniguchi K
    • Journal Title

      Journal of Virology 77

      Pages: 3542-3548

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14370105
  • [Journal Article] Utility of the dried blood on filter paper as a source of cytokine mRNA for the analysis of immunoreactions in Plasmodium yoelii infection.2003

    • Author(s)
      Maeno, Y., Nakazawa, S., Nagashima, S., Sasaki, J., Higo, K.M.Taniguchi, K.
    • Journal Title

      Acta Tropica 87

      Pages: 295-300

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14570225
  • [Presentation] IFITM1はゴルジ体へのコレステロール輸送を促進することでアイチウイルスゲノムの複製を亢進する2023

    • Author(s)
      佐々木 潤 、佐々木 球美子、村田 貴之
    • Organizer
      第70回 日本ウイルス学会学術集会
    • Data Source
      KAKENHI-PROJECT-20K07529
  • [Presentation] IFITM1はアイチウイルスゲノムの複製を亢進する2021

    • Author(s)
      佐々木球美子, 村田 貴之, 佐々木 潤
    • Organizer
      第68回日本ウイルス学会学術集会
    • Data Source
      KAKENHI-PROJECT-20K07529
  • [Presentation] 脂肪酸不飽和化酵素SCD1は効率的なアイチウイルスゲノム複製に必要である。2019

    • Author(s)
      佐々木潤、村田貴之
    • Organizer
      第67回日本ウイルス学会学術集会
    • Data Source
      KAKENHI-PROJECT-16K08819
  • [Presentation] The ER proteins, VAPA and VAPB, are required for Aichi virus RNA replication2015

    • Author(s)
      Kumiko Ishikawa-Sasaki, Jun Sasaki, Shigeo Nagashima, Yoshimasa Maeno, Kyoko Moriguchi, Satoshi Komoto, Koki Taniguchi
    • Organizer
      第63回日本ウイルス学会
    • Place of Presentation
      福岡県福岡市
    • Year and Date
      2015-11-22
    • Data Source
      KAKENHI-PROJECT-25460572
  • [Presentation] アイチウイルスゲノムの複製にはOSBP とそれを介する複製部位へのコレステロール蓄積が必須である.2014

    • Author(s)
      佐々木球美子、佐々木潤、前野芳正、守口匡子、河本聡志、谷口孝喜
    • Organizer
      第62回日本ウイルス学会学術集会
    • Place of Presentation
      横浜市 パシフィコ横浜会議センター
    • Year and Date
      2014-11-10
    • Data Source
      KAKENHI-PROJECT-25460572
  • [Presentation] A Golgi protein interacting with 2B, 2BC, 2C, 3A and 3AB is a host factor required for Ai chi virus RNA replication2011

    • Author(s)
      Ishikawa K, Sasaki J, Maeno Y, Moriguchi K, Komoto S, Taniguchi K
    • Organizer
      International Union of Microbiological Societies 2011 Congress
    • Place of Presentation
      札幌コンベンションセンター(北海道)
    • Year and Date
      2011-09-15
    • Data Source
      KAKENHI-PROJECT-21590514
  • [Presentation] A Golgi protein interacting with 2B, 2BC, 2C, 3A and 3AB is a host factor required for Aichi virus RNA replication2011

    • Author(s)
      Ishikawa K, Sasaki J, Maeno Y, Moriguchi K, Komoto S, Taniguchi K
    • Organizer
      International Union of Microbiological Societies 2011 Congress
    • Place of Presentation
      札幌コンベンションセンター(北海道)
    • Data Source
      KAKENHI-PROJECT-21590514
  • [Presentation] Cleavage at the N-terminus of 2A by 3CD of Aichi virus2009

    • Author(s)
      佐々木潤
    • Organizer
      第9回あわじしま感染症・免疫フォーラム
    • Place of Presentation
      兵庫県淡路市 兵庫県立淡路夢舞台国際会議場
    • Year and Date
      2009-09-10
    • Data Source
      KAKENHI-PROJECT-21590514
  • [Presentation] アイチウイルス3CDによる2AのN末端の切断2009

    • Author(s)
      佐々木潤、石川球美子、前野芳正、河本聡志、守口匡子、谷口孝喜
    • Organizer
      第57回日本ウイルス学会学術集会
    • Place of Presentation
      東京都都市センターホテル
    • Year and Date
      2009-10-25
    • Data Source
      KAKENHI-PROJECT-21590514
  • [Presentation] Cleavage at the N-terminus of 2A by 3CD of Aichi virus2009

    • Author(s)
      Sasaki J, Ishikawa K, Taniguchi K
    • Organizer
      第9回あわじしま感染症・免疫フォーラム
    • Place of Presentation
      兵庫県淡路市兵庫県立淡路夢舞台国際会議場
    • Year and Date
      2009-09-10
    • Data Source
      KAKENHI-PROJECT-21590514
  • [Presentation] アイチウイルス3CDによる2AのN末端の切断2009

    • Author(s)
      佐々木潤
    • Organizer
      第57回日本ウイルス学会学術集会
    • Place of Presentation
      東京都 都市センターホテル
    • Year and Date
      2009-10-25
    • Data Source
      KAKENHI-PROJECT-21590514
  • [Presentation] アイチウイルスLタンパク質がポリプロテインの細胞内局在におよぼす影響の解析2007

    • Author(s)
      佐々木 潤
    • Organizer
      第55回日本ウイルス学会学術集会
    • Place of Presentation
      札幌
    • Year and Date
      2007-10-23
    • Data Source
      KAKENHI-PROJECT-18790328
  • 1.  MAENO Yoshimasa (70131191)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 2.  TANIGUCHI Koki (40094213)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 3.  MORIGUCHI Kyoko (60298528)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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