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Yoshioka Kenichi  吉岡 研一

ORCIDConnect your ORCID iD *help
… Alternative Names

吉岡 研一  ヨシオカ ケンイチ

YOSHIOKA Ken-ichi  吉岡 研一

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Researcher Number 70321916
Other IDs
Affiliation (Current) 2022: 国立研究開発法人国立がん研究センター, 研究所, ユニット長
Affiliation (based on the past Project Information) *help 2021: 国立研究開発法人国立がん研究センター, 研究所, ユニット長
2009: Tokyo Medical and Dental University, 研究所, 主任研究官
2009: National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East, 研究所, 主任研究官
2007 – 2008: Tokyo Medical and Dental University, Medical Research Institute, Assistant Professor
Review Section/Research Field
Principal Investigator
Molecular biology / Basic Section 63020:Radiation influence-related
Except Principal Investigator
Cell biology / General surgery
Keywords
Principal Investigator
ゲノム不安定性 / ミスマッチ修復 / マイクロサテライト不安定性 / DNA複製 / クロモソーマル不安定性 / DNA複製ストレス / NDA損傷 / 発がん / ミスマッチ修復因子 / 加齢 … More / H2AX / 放射線 / UV / がん / DNA損傷 … More
Except Principal Investigator
ES細胞 / 再生医療 / DNA修復 / DNA損傷応答 / ゲノム安定化 / 霊長瀬 / DNA2重鎖切断 / 再生医学 / 霊長類 / 肝細胞 / 細胞移植 / 胆管 / 肝芽細胞 / ex utero移植法 / iPS細胞 / 肝機能障害治療 / 肝外胆管 / ES cell / Hepatocyte / Regenerative medicine / Cell transplantation / Bile duct / Hepatoblast / ex utero surgery / iPS cell Less
  • Research Projects

    (4 results)
  • Research Products

    (9 results)
  • Co-Researchers

    (13 People)
  •  放射線およびUVばく露によるゲノム不安定性リスクに対する影響の研究Principal Investigator

    • Principal Investigator
      吉岡 研一
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 63020:Radiation influence-related
    • Research Institution
      National Cancer Center Japan
  •  Regulations of mismatch repair proteins for cancer preventionPrincipal Investigator

    • Principal Investigator
      YOSHIOKA Ken-ichi
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Molecular biology
    • Research Institution
      Tokyo Medical and Dental University
  •  胚性幹(ES)細胞におけるDNA二重鎖切断修復の特徴

    • Principal Investigator
      TERAOKA Hirobumi
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Cell biology
    • Research Institution
      Tokyo Medical and Dental University
  •  Studies of regenerative medicine on differentiation into hepatic and bile duct cells for preclinical trial to surgery

    • Principal Investigator
      TERAOKA Hirobumi, 寺本 研一
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General surgery
    • Research Institution
      Tokyo Medical and Dental University

All 2021 2010 2008

All Journal Article Presentation

  • [Journal Article] Genomic Instability and Cancer Risk Associated with Erroneous DNA Repair.2021

    • Author(s)
      Yoshioka Ken-ichi、Kusumoto-Matsuo Rika、Matsuno Yusuke、Ishiai Masamichi
    • Journal Title

      Int. J. Mol. Sci.

      Volume: 22 Pages: 12254-12254

    • DOI

      10.3390/ijms222212254

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21J40157, KAKENHI-PROJECT-18K11642, KAKENHI-PROJECT-20K12159, KAKENHI-PROJECT-21K12252
  • [Journal Article] Replication-stress-associated DSBs induced by ionizing radiation risk genomic destabilization and associated clonal evolution2021

    • Author(s)
      Matsuno Y, Hyodo M, Suzuki M, Tanaka Y, Horikoshi Y, Murakami Y, Torigoe H, Mano H, Tashiro S, Yoshioka KI.
    • Journal Title

      iScience

      Volume: 24 Pages: 102313-102313

    • DOI

      10.1016/j.isci.2021.102313

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21H04927, KAKENHI-PROJECT-21J12419, KAKENHI-PROJECT-21K12252
  • [Journal Article] DNA Lesions Induced by Replication Stress Trigger Mitotic Aberration and Tetraploidy Development.2010

    • Author(s)
      Ichijima, Y., Yoshioka, K., * Yoshioka, Y., Shinohe, K., Fujimori, H., Unno, J., Takagi, M., Goto, H., Inagaki, I., Mizutani, S., Teraoka, H.
    • Journal Title

      PLoS ONE 5

    • Data Source
      KAKENHI-PROJECT-20770136
  • [Journal Article] The Mismatch Repair-Mediated Cell Cycle Checkpoint Response to Fluorodeoxyuridine2008

    • Author(s)
      Liu, A., Yoshioka, K., Salerno, V., & Hsieh, P.
    • Journal Title

      J. Cellular Biochem 105

      Pages: 245-254

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20770136
  • [Journal Article] The Mismatch Repair-Mediated Cell Cycle Checkpoint Response to Fluorodeoxyuridine.2008

    • Author(s)
      Liu, A., Yoshioka, K., Salerno, V., Hsieh, P.
    • Journal Title

      J Cellular Biochem 105

      Pages: 245-254

    • Data Source
      KAKENHI-PROJECT-20770136
  • [Presentation] ゲノム安定性制御を作用点としたがん予防への挑戦2021

    • Author(s)
      吉岡研一
    • Organizer
      日本抗加齢医学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K12252
  • [Presentation] 放射線で誘導される複製ストレスに起因したゲノム不安定性リスクとこれに伴うクローン進化2021

    • Author(s)
      吉岡研一
    • Organizer
      放射線影響学会
    • Data Source
      KAKENHI-PROJECT-21K12252
  • [Presentation] 老化細胞の形質転換は、H2AXの減少-DNA修復能の低下-DNA損傷の蓄積DNAの傷のM期への進行-ゲノム不安定化を経由して誘導される2008

    • Author(s)
      吉岡研一
    • Organizer
      日本分子生物学会
    • Place of Presentation
      神戸
    • Year and Date
      2008-12-10
    • Data Source
      KAKENHI-PROJECT-20770136
  • [Presentation] 老化細胞の形質転換は、H2AXの減少-DNA修復能の低下-DNA損傷の蓄積-DNAの傷のM期への進行-ゲノム不安定化を経由して誘導される2008

    • Author(s)
      吉岡研一
    • Organizer
      日本分子生物学会
    • Place of Presentation
      神戸
    • Year and Date
      2008-12-10
    • Data Source
      KAKENHI-PROJECT-20770136
  • 1.  TERAOKA Hirobumi (30019137)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 2.  朝比奈 欣治 (40345294)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 3.  斉藤 佳子 (50178969)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  ARII Shigeki (50151171)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  TANAKA Yujiro (70236644)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  ISEKI Sachiko (80251544)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  TAKASE Kozo (90211333)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  寺本 研一 (80197813)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  MATSUO Rika
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 10.  SUN Jying
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 11.  石合 正道
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 12.  田代 聡
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 13.  堀越 保則
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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